Ligand cyanate

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Basic Ligand Information

Molecular Structure
Picture of cyanate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
CHNO
cyanate
XLJMAIOERFSOGZ-UHFFFAOYSA-M
Synonyms:
cyanate (NCO-), NCO-, OCN-


Show all pahtways known for Show all BRENDA pathways known for cyanate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cyanate + dithioerythritol = ?
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
stimulates
-

Inhibitor in Enzyme-catalyzed Reactions (37 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
50 mM, complete loss of activity
-
formate oxidation is inhibited strongly and competitively whereas CO2 reduction is inhibited weakly and not competitively; strongly inhibits the oxidation of formate, whereas CO2 reduction is inhibited only weakly and not competitively
-
27% inhibition at 2 mM
-
500 mM, 15% inhibition
-
Ki of strain AI3 is 1.1 mM, Ki of strain AIU1N is 1.8 mM and Ki of strain OUCH4 is 50 mM; reversible inhibition, pH 7.2 and 37°C
-
significant inhibition
-
2 mM ibuprofen and its major metabolites protect by up to 26%. Ibuprofen and the metabolites do not bind to fumarase
-
competitively inhibits nitrite transport
-

3D Structure of Enzyme-Ligand-Complex (PDB) (3 results)

Enzyme Kinetic Parameters

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (16 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
TABLE ID
0.2
-
-
34359

IC50 Value (2 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE

References & Links

Links to other databases for cyanate

ChEBI
PubChem
ChEBI
PubChem