Ligand 4-chlorobenzoyl-CoA

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Basic Ligand Information

Molecular Structure
Picture of 4-chlorobenzoyl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C28H39ClN7O17P3S
4-chlorobenzoyl-CoA
DEPSOKCZMQPCBI-TYHXJLICSA-N
Synonyms:
4-chlorobenzoyl-coenzyme A

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl-CoA + chloride
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,4-dichlorobenzoyl-CoA + NADPH = 4-chlorobenzoyl-CoA + NADP+ + chloride
show the reaction diagram
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4-Chlorobenzoate + CoA + ATP = 4-Chlorobenzoyl-CoA + AMP + diphosphate
show the reaction diagram
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-

Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-chlorobenzoyl-CoA + H2O = CoA + 4-chlorobenzoate
show the reaction diagram
-
4-Chlorobenzoyl-CoA + H2O = 4-Chlorobenzoate + CoA
show the reaction diagram
-
4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl-CoA + chloride
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2,4-dichlorobenzoyl-CoA + NADPH = 4-chlorobenzoyl-CoA + NADP+ + chloride
show the reaction diagram
-
ATP + 4-chlorobenzoate + CoA = AMP + diphosphate + 4-chlorobenzoyl-CoA
show the reaction diagram
-
ATP + 4-chlorobenzoate + CoA = AMP + diphosphate + 4-chlorobenzoyl-CoA
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (29 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.0032
-
wild-type protein, pH7.5, 25°C
1.1
-
pH 7.5, 25°C

KM Value (25 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.13
-
wild-type protein, pH7.5, 25°C

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
TABLE ID
0.055
-
wild-type enzyme, pH 7.5, 25°C
34907

References & Links

Links to other databases for 4-chlorobenzoyl-CoA

ChEBI
PubChem
ChEBI
PubChem