Ligand linoleoyl-CoA

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Basic Ligand Information

Molecular Structure
Picture of linoleoyl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C39H66N7O17P3S
linoleoyl-CoA
YECLLIMZHNYFCK-RRNJGNTNSA-N
Synonyms:
(9Z,12Z)-octadecadienoyl-CoA, linoleoyl-[CoA]

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-palmitoyl-2-lysophosphatidylcholine + linoleoyl-CoA = 1-palmitoyl-2-linoleoylphosphatidylcholine + CoA
show the reaction diagram
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linoleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine = CoA + 1-alkenyl-2-linoleoyl-glycero-3-phosphorylcholine
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
oleoyl-[CoA] + ferrocytochrome b5 + O2 + H+ = linoleoyl-[CoA] + ferricytochrome b5 + H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (49 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
linoleoyl-CoA + NADPH = cis-9,12-octadecadienal + NADP+ + CoA
show the reaction diagram
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linoleoyl-CoA + O2 = 2-trans-9-trans-12-trans-octadecatrienoyl-CoA + H2O2
show the reaction diagram
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linoleoyl-CoA + oxidized electron transfer flavoprotein = ? + reduced electron transfer flavoprotein
show the reaction diagram
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linoleoyl-CoA + 1-alkenylglycerophosphoethanolamine = CoA + 1-alkenyl-2-linoleoylglycerophosphoethanolamine
show the reaction diagram
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linoleoyl-CoA + 1-O-hexadecyl-2-acetyl-sn-glycerol = CoA + 1-O-hexadecyl-2-acetyl-3-linoleoyl-sn-glycerol
show the reaction diagram
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linoleoyl-CoA + L-carnitine = CoA + L-linoleoylcarnitine
show the reaction diagram
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linoleoyl-CoA + sn-2-monooleoylglycerol = CoA + 1-linoleoyl-2-oleoylglycerol
show the reaction diagram
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linoleoyl-CoA + 1-alkenyl-glycero-3-phosphorylcholine = CoA + 1-alkenyl-2-linoleoyl-glycero-3-phosphorylcholine
show the reaction diagram
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linoleoyl-CoA + cholesterol = CoA + cholesteryl linoleate
show the reaction diagram
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linoleoyl-CoA + 2-acyl-sn-glycerol 3-phosphate = CoA + 1-linoleoyl-2-acyl-sn-glycerol 3-phosphate
show the reaction diagram
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linoleoyl-CoA + 1-alkyl-sn-glycero-3-phosphocholine = CoA + 2-linoleoyl-1-alkyl-sn-glycero-3-phosphocholine
show the reaction diagram
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linoleoyl-CoA + glycerophosphocholine = CoA + 1-linoleoyl-sn-glycero-3-phosphocholine
show the reaction diagram
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linoleoyl-CoA = (10Z,12Z)-octadeca-10,12-dienoyl-CoA
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
oleoyl-[CoA] + ferrocytochrome b5 + O2 + H+ = linoleoyl-[CoA] + ferricytochrome b5 + H2O
show the reaction diagram
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Enzyme Cofactor/Cosubstrate (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
absolutely essential for DELTA6-desaturation
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Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (17 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.045
-
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0.00021
-
-
0.0085
-
-
0.047
-
-
0.0028
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References & Links

Links to other databases for linoleoyl-CoA

ChEBI
PubChem
ChEBI
PubChem