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Information on EC 7.6.2.4 - ABC-type fatty-acyl-CoA transporter

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IUBMB Comments
An ATP-binding cassette (ABC) type transporter, characterized by the presence of two similar ATP-binding domains/proteins and two integral membrane domains/proteins. Does not undergo phosphorylation during the transport process. An animal and yeast enzyme that transports fatty acyl CoA into and out of peroxisomes. In humans, it is associated with Zellweger's syndrome.
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
+
+
fatty acyl CoA[side 1]
=
+
+
fatty acyl CoA[side 2]
Synonyms
70-kDa peroxisomal membrane protein, ABC half transporter, ABCD1, ABCD2, ABCD3, ABCD4, adrenoleukodystrophy protein, adrenoleukodystrophy-related protein, ALD-related protein, ALDP, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + H2O + fatty acyl CoA[side 1] = ADP + phosphate + fatty acyl CoA[side 2]
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