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Disease on EC 7.2.2.3 - P-type Na+ transporter

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acidosis
Alterations in cell function with ischemia and shock and their correction.
An immunocytochemical study of H+ ATPase in kidney transplant rejection.
Environmental distal renal tubular acidosis in Thailand: an enigma.
Enzymatic and functional evidence for adaptation of the vacuolar H(+)-ATPase in proximal tubule apical membranes from rats with chronic metabolic acidosis.
Lactic acidosis progressively impairs dopamine uptake in rat striatal synaptosomes by a mechanism partially independent of the Na+/K+-ATPase dysfunction.
Magnesium role in cardiovascular diseases.
The acute effects of glycemic control on nerve conduction in human diabetics.
[Effect of acidosis on membrane potential and calcium transport in rat brain synaptosomes]
Acidosis, Lactic
Lactic acidosis progressively impairs dopamine uptake in rat striatal synaptosomes by a mechanism partially independent of the Na+/K+-ATPase dysfunction.
Acidosis, Renal Tubular
An immunocytochemical study of H+ ATPase in kidney transplant rejection.
Environmental distal renal tubular acidosis in Thailand: an enigma.
Acquired Immunodeficiency Syndrome
Cytochemical localization of Na+/K+-ATPase activity in cochlear strial marginal cells after various catecholamine administrations.
Acromegaly
Basal metabolic rate in adults with growth hormone deficiency and in patients with acromegaly: relationship with lean body mass, plasma insulin level and leucocyte sodium pump activity.
Evidence of an endogenous digitalis-like factor in the plasma of patients with acromegaly.
Increased activity of digoxin-like substance in low-renin hypertension in acromegaly.
Leucocyte sodium transport in acromegaly.
Acute Kidney Injury
Effects of acute and chronic uremia on active cation transport in rat myocardium.
The pathophysiology of septic shock: acute renal failure in rats following live E coli injection. A histochemical study of the proximal tubules.
Adenocarcinoma
Comparison of adenosine triphosphatase activity of nuclei and mitochondria from mouse mammary adenocarcinoma.
Identification of Proteins Whose Interaction with Na+,K+-ATPase Is Triggered by Ouabain.
Immunohistochemical localization of sodium-potassium-stimulated adenosine triphosphatase and carbonic anhydrase in human colon and colonic neoplasms.
Oxidative Stress and Apoptotic Responses Elicited by Nostoc-Synthesized Silver Nanoparticles against Different Cancer Cell Lines.
[Na+,K+ -ATPase activity characteristics in human colon adenocarcinoma]
Adenocarcinoma of Lung
[Expression of Copper-Transporting P-Type Adenosine Triphosphatase (ATP7B) Correlates with Cisplatin-Resistance in Human Lung Adenocarcinoma Cell Line A549.]
Adenocarcinoma, Papillary
Immunohistochemical and histochemical markers of primary lung cancer, lung metastases, and pleural mesotheliomas.
Adenoma
Gene mutations that promote adrenal aldosterone production, sodium retention, and hypertension.
Immunohistochemical localization of sodium-potassium-stimulated adenosine triphosphatase and carbonic anhydrase in human colon and colonic neoplasms.
[Enzymatic activity of adenosine triphosphatase and acid phosphatase in adenoma of the tongue]
Adenoma, Oxyphilic
Mitochondrial adenosine triphosphatase in the oxyphil cells of a renal oncocytoma.
Adenoma, Pleomorphic
A cytochemical study on the salivary gland pleomorphic adenoma (mixed tumor) and the fetal and adult salivary gland.
Adrenal Insufficiency
The human leucocyte sodium pump in adrenocortical insufficiency.
Albuminuria
Hyperaldosteronemia and activation of the epithelial sodium channel are not required for sodium retention in puromycin-induced nephrosis.
Alkalosis
Is the alkaline tide a signal to activate metabolic or ionoregulatory enzymes in the dogfish shark (Squalus acanthias)?
Recovery from blood alkalosis in the Pacific hagfish (Eptatretus stoutii): involvement of gill V-H+-ATPase and Na+/K+-ATPase.
Altitude Sickness
Transport ATPases in the erythrocytes of rats acclimatized to intermittent altitude hypoxia.
Alzheimer Disease
Alzheimer A? Assemblies Accumulate in Excitatory Neurons upon Proteasome Inhibition and Kill Nearby NAK?3 Neurons by Secretion.
Effect of a purine derivative containing selenium to improve memory decline and anxiety through modulation of the cholinergic system and Na+/K+-ATPase in an Alzheimer's disease model.
Genetic variability in copper-transporting P-type adenosine triphosphatase (ATP7B) is associated with Alzheimer's disease in a Chinese population.
Phosphatidylinositol and PI-4-monophosphate recover amyloid beta protein-induced inhibition of Cl- -ATPase activity.
Regulation of the frontocortical sodium pump by Na+ in Alzheimer's disease: difference from the age-matched control but similarity to the rat model.
Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders--Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy.
Amyotrophic Lateral Sclerosis
Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks.
Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders--Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy.
Anemia
Abnormalities in adenosine triphosphatase of the erythrocyte membrane in iron deficiency anaemia.
[Some data on the activity of adenosine triphosphatase and acetylcholinesterase in the erythrocytes of patients with various forms of anemia]
[Studies on renal anemias. 3. The behavior of the phosphoric esters of adenosine and adenosine triphosphatase of the erythrocytes in hyperazotemic states]
Anemia, Hemolytic
A new mutation of Wilson's disease P-type ATPase gene in a patient with cirrhosis and coombs-positive hemolytic anemia.
Congenital non-spherocytic haemolytic anaemia variants with primary and secondary pyruvate kinase deficiency. II. Enzymatic studies.
[Adenosine triphosphatase (ATP-ase) deficiency in a family with nonspherocytic hemolytic anemia]
[Adenosine triphosphatase activity in normal persons and patients with hemolytic anemia]
[Experimental hemolytic anemia induced by hetero-antisera. I. Behavior of the adenosine triphosphatase activity of erythrocytes.]
Anemia, Iron-Deficiency
Abnormalities in adenosine triphosphatase of the erythrocyte membrane in iron deficiency anaemia.
Anemia, Pernicious
Fas/CD95 is required for gastric mucosal damage in autoimmune gastritis.
Monoclonal antibodies specific for the core protein of the beta-subunit of the gastric proton pump (H+/K+ ATPase). An autoantigen targetted in pernicious anaemia.
Aneurysm
A Novel ATP1A2 Gene Variant Associated With Pure Sporadic Hemiplegic Migraine Improved After Patent Foramen Ovale Closure: A Case Report.
Apnea
2B.03: URIC ACID LEVELS RELATED TO OBSTRUCTIVE SLEEP APNEA SYNDROME IN PATIENTS WITH HYPERTENSION FROM XINJIANG OF CHINA.
Arrhythmias, Cardiac
Angiotensin receptor-neprilysin inhibitior (thiorphan/irbesartan) decreased ischemia-reperfusion induced ventricular arrhythmias in rat; in vivo study.
Beneficial effect of eplerenone on cardiac remodelling and electrical properties of the failing heart.
Cardenolides: Insights from chemical structure and pharmacological utility.
Digitalis toxicity: lack of marked effect on brain na+,k+-adenosine triphosphatase in the cat.
Evidence against an involvement of Na+, K+-ATPase in antiarrhythmic mechanism of phenytoin.
Exposure to low-level metalaxyl impacts the cardiac development and function of zebrafish embryos.
Investigation of cardiac glycosides from oleander in a human induced pluripotent stem cells derived cardiomyocyte model.
The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction.
Arteriosclerosis
[Studies on arteriosclerosis and endangitis obliterans. VIII. Hexokinase and adenosine triphosphatase in skeletal muscles in peripheral vascular disorders.]
Arteritis
Coronavirus interactions with the cellular autophagy machinery.
Arthritis, Rheumatoid
Adenosine triphosphatase activity in blood in rheumatoid arthritis.
Decreased NA+, K+-ATPase activity in erythrocyte membrane from rheumatoid arthritis patients.
Arthrogryposis
ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.
Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations.
Asthma
Decreased sodium-potassium and calcium adenosine triphosphatase activity in asthma: modulation by inhaled and oral corticosteroids.
Increased intracellular calcium and decreased activities of leucocyte Na+,K+-ATPase and Ca2+-ATPase in asthma.
Leukocyte adenosine triphosphatase activity in human bronchial asthma.
[Increase of serum adenosine triphosphatase in bronchial asthma states]
Astrocytoma
Sodium-potassium adenosine triphosphatase activity in N-nitrosomethylurea-induced rat astrocytoma cells.
Ataxia
A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients.
High mitochondrial DNA T8993G mutation (<90%) without typical features of Leigh's and NARP syndromes.
Migrainous vertigo: mutation analysis of the candidate genes CACNA1A, ATP1A2, SCN1A, and CACNB4.
Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures.
Atrial Fibrillation
Cardenolides: Insights from chemical structure and pharmacological utility.
Down-regulation of L-type calcium channel and sarcoplasmic reticular Ca(2+)-ATPase mRNA in human atrial fibrillation without significant change in the mRNA of ryanodine receptor, calsequestrin and phospholamban: an insight into the mechanism of atrial electrical remodeling.
Bacteremia
The pathophysiology of septic shock: acute renal failure in rats following live E coli injection. A histochemical study of the proximal tubules.
Bartter Syndrome
The effect of long-term treatment with spironolactone on sodium pump abnormalities in the red blood cells of patients with Bartter's syndrome.
Bone Resorption
Comparative analysis of the effects of a novel vacuolar adenosine 5'-triphosphatase inhibitor, FR202126, and doxycycline on bone loss caused by experimental periodontitis in rats.
Metabolic activation stimulates acid secretion and expression of matrix degrading proteases in human osteoblasts.
Proton pumping V-ATPase inhibitor bafilomycin A1 affects Rab7 lysosomal localization and abolishes anterograde trafficking of osteoclast secretory lysosomes.
Bradycardia
Mechanism in bradycardia induced by Trimethyltin chloride: Inhibition activity and expression of Na+/K+-ATPase and apoptosis in myocardia.
Mutation of the Na+/K+-ATPase Atp1a1a.1 causes QT interval prolongation and bradycardia in zebrafish.
Brain Diseases
Acute encephalopathy in familial hemiplegic migraine with ATP1A2 mutation.
ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.
Early onset severe ATP1A2 epileptic encephalopathy: Clinical characteristics and underlying mutations.
Early Treatment in Acute Severe Encephalopathy Caused by ATP1A2 Mutation of Familial Hemiplegic Migraine Type 2: Case Report and Literature Review.
Familial Hemiplegic Migraine With Asymmetric Encephalopathy Secondary to ATP1A2 Mutation: A Case Series.
Na+/K+-ATPase activity and GABA uptake in astroglial cell-enriched fractions and synaptosomes derived from rats in the early stage of experimental hepatogenic encephalopathy.
Brain Edema
Brain damage related to hemorrhagic transformation following cerebral ischemia and the role of K ATP channels.
Effects of repeated brain ischemia induced by rapid lower body negative pressure on brain water and Na+,K+-ATPase activity in rats.
Inhibition of rat brain Na+,K+-ATPase activity by serum from patients with fulminant hepatic failure.
Neurologic manifestations of diabetic comas: correlation with biochemical alterations in the brain.
Potassium Aspartate Attenuates Brain Injury Induced by Controlled Cortical Impact in Rats Through Increasing Adenosine Triphosphate (ATP) Levels, Na+/K+-ATPase Activity and Reducing Brain Edema.
The endogenous ouabain-like sodium pump inhibitor in cold injury-induced brain edema.
Brain Injuries
Down-regulated Na(+)/K(+)-ATPase activity in ischemic penumbra after focal cerebral ischemia/reperfusion in rats.
Na+,K+-ATPase activity impairment after experimental traumatic brain injury: relationship to spatial learning deficits and oxidative stress.
Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study.
Potassium Aspartate Attenuates Brain Injury Induced by Controlled Cortical Impact in Rats Through Increasing Adenosine Triphosphate (ATP) Levels, Na+/K+-ATPase Activity and Reducing Brain Edema.
[Study on regulation of tanshinone II(A) on GFAP and ATPase and PDI of cerebral ischemia reperfusion injury in rats].
Brain Injuries, Traumatic
Na+,K+-ATPase activity impairment after experimental traumatic brain injury: relationship to spatial learning deficits and oxidative stress.
Brain Ischemia
Combined actions of Na/K-ATPase, NCX1 and glutamate dependent NMDA receptors in ischemic rat brain penumbra.
Effect of deferoxamine on Na+K+ATPase activity after cerebral ischemia in rabbits.
Effects of repeated brain ischemia induced by rapid lower body negative pressure on brain water and Na+,K+-ATPase activity in rats.
Insights into the neuropathology of cerebral ischemia and its mechanisms.
Preconditioning prevents the inhibition of Na+,K+-ATPase activity after brain ischemia.
The influence of MK-801 on the hippocampal free arachidonic acid level and Na+,K+-ATPase activity in global cerebral ischemia-exposed rats.
[Study on regulation of tanshinone II(A) on GFAP and ATPase and PDI of cerebral ischemia reperfusion injury in rats].
Brain Neoplasms
Present and potential future adjuvant issues in high-grade astrocytic glioma treatment.
Spider venom components decrease glioblastoma cell migration and invasion through RhoA-ROCK and Na+/K+-ATPase ?2: potential molecular entities to treat invasive brain cancer.
Breast Neoplasms
Abnormal expression of ATP1A1 and ATP1A2 in breast cancer.
An easy and fast adenosine 5'-diphosphate quantification procedure based on hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry for determination of the in vitro adenosine 5'-triphosphatase activity of the human breast cancer resistance protein ABCG2.
BRIP1 inhibits the tumorigenic properties of cervical cancer by regulating RhoA GTPase activity.
Copper-transporting P-type adenosine triphosphatase (ATP7B) is expressed in human breast carcinoma.
Digitalis-induced signaling by Na+/K+-ATPase in human breast cancer cells.
Glyceraldehyde-3-phosphate dehydrogenase as a surface associated antigen on human breast cancer cell lines MACL-1 and MGSO-3.
Identification of a sodium pump Na+/K+ ATPase ?1-targeted peptide for PET imaging of breast cancer.
Inner Blood-Retinal Barrier Dominantly Expresses Breast Cancer Resistance Protein: Comparative Quantitative Targeted Absolute Proteomics Study of CNS Barriers in Pig.
Oleandrin, a cardiac glycoside, induces immunogenic cell death via the PERK/elF2?/ATF4/CHOP pathway in breast cancer.
On the importance and mechanism of amplification of digitalis signal through Na+/K+-ATPase.
Oxidative Stress and Apoptotic Responses Elicited by Nostoc-Synthesized Silver Nanoparticles against Different Cancer Cell Lines.
Pentoxifylline and its major oxidative metabolites exhibit different pharmacological properties.
[A Simple Medical Research Microdevice for Analyzing Three-dimensional Migration of Tumor Cells in Vitro].
Bronchitis
Coronavirus interactions with the cellular autophagy machinery.
Carcinogenesis
ATP6AP2 is Overexpressed in Breast Cancer and Promotes Breast Cancer Progression.
BRIP1 inhibits the tumorigenic properties of cervical cancer by regulating RhoA GTPase activity.
Bufalin inhibits glioblastoma growth by promoting proteasomal degradation of the Na+/K+-ATPase ?1 subunit.
Integrative Transcriptomic, Proteomic and Functional Analysis Reveals ATP1B3 as a Diagnostic and Potential Therapeutic Target in Hepatocellular Carcinoma.
Carcinoma
A moving new role for the sodium pump in epithelial cells and carcinomas.
Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways.
Changes of enzyme activities recognized in lymphocytes from patients with carcinoma of the gastrointestinal tract.
Copper-transporting P-type adenosine triphosphatase (ATP7B) as a cisplatin based chemoresistance marker in ovarian carcinoma: comparative analysis with expression of MDR1, MRP1, MRP2, LRP and BCRP.
Copper-transporting P-type adenosine triphosphatase (ATP7B) is expressed in human gastric carcinoma.
Distribution of adenosine triphosphatase in infiltrating ductal carcinoma and non-neoplastic breast.
Effects of SLC31A1 and ATP7B polymorphisms on platinum resistance in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiotherapy.
Elevated lymphocyte adenosine triphosphatase activity in patients with gastrointestinal carcinoma.
Emergency Use of Targeted Osmotic Lysis for the Treatment of a Patient with Aggressive Late-Stage Squamous Cell Carcinoma of the Cervix.
Enzymatic responses of transplanted tumour cells towards estrogen, progesterone and testosterone.
Enzyme histochemistry and thyroid neoplasia.
Expression and cisplatin sensitivity of copper-transporting P-type adenosine triphosphatase (ATP7B) in human solid carcinoma cell lines.
Expression of ATP7A in esophageal squamous cell carcinoma (ESCC) and its clinical significance.
Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a chemoresistance marker in human oral squamous cell carcinoma treated with cisplatin.
Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a chemoresistance marker in human solid carcinomas.
Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) correlates with cisplatin resistance in human non-small cell lung cancer xenografts.
Expression of copper-transporting P-type adenosine triphosphatase in human esophageal carcinoma.
Immunohistochemical localization of Na+, K+-ATPase in human normal and malignant pancreatic tissues.
Inhibition of Na+,K+-ATPase by cisplatin and its recovery by 2-mercaptoethanol in human squamous cell carcinoma cells.
Interaction of asterriquinone with deoxyribonucleic acid in vitro.
Is ATP7B a predictive marker in patients with ovarian carcinoma treated with platinum-taxane combination chemotherapy?
Mutation analysis of copper-transporting P-type adenosine triphosphatase (ATP7B) in human solid carcinomas.
Novel progesterone target genes identified by an improved differential display technique suggest that progestin-induced growth inhibition of breast cancer cells coincides with enhancement of differentiation.
Carcinoma in Situ
Polarization of the vacuolar adenosine triphosphatase delineates a transition to high-grade pancreatic intraepithelial neoplasm lesions.
Carcinoma, Ductal
Distribution of adenosine triphosphatase in infiltrating ductal carcinoma and non-neoplastic breast.
Carcinoma, Ehrlich Tumor
A Mg2+- and Ca2+-stimulated adenosine triphosphatase at the outer surface of Ehrlich ascites tumor cells.
Increase in adenosine triphosphatase activity of Ehrlich ascites tumor cells following serial cultivation in media with increased (hypertonic) NaCl content.
Inhibition of tumor growth by an alkylation of the plasma membrane.
Quercetin inhibition of the induction and function of cytotoxic T lymphocytes.
Carcinoma, Hepatocellular
Adenosine triphosphatase pontin is overexpressed in hepatocellular carcinoma and coregulated with reptin through a new posttranslational mechanism.
Cinobufagin Triggers Defects in Spindle Formation and Cap-Dependent Translation in Liver Cancer Cells by Inhibiting the AURKA-mTOR-eIF4E Axis.
Cytochemical studies of acid phosphatase, adenosine triphosphatase and lactic dehydrogenase activity in thioacetamide-induced hepatoma.
Deficiency of uncoupler-stimulated adenosine triphosphatase activity in tightly coupled hepatoma mitochondria.
Effects of db-cAMP and theophylline on cell surface adenosine triphosphatase activity in cultured hepatoma cells.
Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) in human hepatocellular carcinoma.
Mitochondrial adenosine triphosphatase of Zajdela hepatoma. III. Effect of uncouplers on the hydrolysis of intramitochondrial ATP.
Mitochondrial ATPase of Zajdela hepatoma. II. Mitochondria of Zajdela hepatoma contain less adenosine triphosphatase than mitochondria of rat liver.
Na+/K+-ATPase ?1 subunit, a novel therapeutic target for hepatocellular carcinoma.
Na+/K+-ATPase ?3 mediates sensitivity of hepatocellular carcinoma cells to bufalin.
Sodium orthovanadate overcomes sorafenib resistance of hepatocellular carcinoma cells by inhibiting Na+/K+-ATPase activity and hypoxia-inducible pathways.
Uncoupler-stimulated adenosine triphosphatase activity. Deficiency in intact mitochondria from Morris hepatomas and ascites tumor cells.
Carcinoma, Non-Small-Cell Lung
Clinical outcome of cisplatin-based chemotherapy is associated with the polymorphisms of GSTP1 and XRCC1 in advanced non-small cell lung cancer patients.
Copper-transporting P-type adenosine triphosphatase (ATP7A) is associated with platinum-resistance in non-small cell lung cancer (NSCLC).
Evaluation of the relationship of erythrocyte membrane Na+/K+-ATPase enzyme activity and tumor response to chemoradiotherapy in patients diagnosed with locally advanced nonsmall cell lung cancer and glioblastoma multiforme.
Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) correlates with cisplatin resistance in human non-small cell lung cancer xenografts.
MiR-495 enhances the sensitivity of non-small cell lung cancer cells to platinum by modulation of copper-transporting P-type adenosine triphosphatase A (ATP7A).
Role of sodium pump systems to determine sensitivity to mitomycin C in non-small cell lung cancer cell lines.
Carcinoma, Renal Cell
Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways.
Carcinoma, Squamous Cell
Cisplatin sensitivity of oral squamous carcinoma cells is regulated by Na+,K+-ATPase activity rather than copper-transporting P-type ATPases, ATP7A and ATP7B.
Inhibition of Na+,K+-ATPase by cisplatin and its recovery by 2-mercaptoethanol in human squamous cell carcinoma cells.
Cardiomegaly
Angiotensin type 1 receptor antagonism with irbesartan inhibits ventricular hypertrophy and improves diastolic function in the remodeling post-myocardial infarction ventricle.
Changes in sarcolemmal adenosine triphosphatase activity and in ouabain sensitivity of rat myocardium in isoproterenol-induced cardiac hypertrophy.
Multiple signal transduction pathways link Na+/K+-ATPase to growth-related genes in cardiac myocytes. The roles of Ras and mitogen-activated protein kinases.
Na+/K+-ATPase alpha isoforms expression in stroke-prone spontaneously hypertensive rat heart ventricles: effect of salt loading and lacidipine treatment.
Pressure-induced cardiac hypertrophy: changes in Na+,K+-ATPase and glycoside actions in cats.
Ral-GTPase interacts with the beta1 subunit of Na+/K+-ATPase and is activated upon inhibition of the Na+/K+ pump.
Regulation of sarco(endo)plasmic reticulum Ca2+ adenosine triphosphatase by phospholamban and sarcolipin: implication for cardiac hypertrophy and failure.
Studies on adenosine triphosphatase activity of rat cardiac myosin in isoproterenol-induced cardiac hypertrophy.
Cardiomyopathies
Cardiomyopathic etiology and SERCA2a reverse remodeling during mechanical support of the failing human heart.
Effects of acute and chronic uremia on active cation transport in rat myocardium.
Effects of chronic, rapid right atrial pacing on cardiac hemodynamics and myofibrillar ATPase activity in piglets.
Safety and efficacy of high-dose adeno-associated virus 9 encoding sarcoplasmic reticulum Ca(2+) adenosine triphosphatase delivered by molecular cardiac surgery with recirculating delivery in ovine ischemic cardiomyopathy.
Sarcoplasmic reticulum adenosine triphosphatase overexpression in the L-type Ca2+ channel mouse results in cardiomyopathy and Ca2+ -induced arrhythmogenesis.
Sodium potassium adenosine triphosphatase (Na/K-ATPase) as a therapeutic target for uremic cardiomyopathy.
Sodium pump and calcium channel modulation of Mg-deficiency cardiomyopathy.
Cardiomyopathy, Dilated
Human myocardial adenosine triphosphatase activities in health and heart failure.
Structure and function of contractile proteins in human dilated cardiomyopathy.
Cardiomyopathy, Hypertrophic
Altered adenosine triphosphatase activities in pigs with naturally occurring hypertrophic cardiomyopathy.
Cardiotoxicity
Cardiotonic Steroids-Mediated Targeting of the Na(+)/K(+)-ATPase to Combat Chemoresistant Cancers.
Comparison of adriamycin- and ouabain-induced cytotoxicity and inhibition of 86rubidium transport in wild-type and ouabain-resistant C3H/10T1/2 mouse fibroblasts.
Molecular mechanisms of bufadienolides and their novel strategies for cancer treatment.
Pharmacological characterization of the activity of endogenous inotropic factor from porcine left ventricle.
Protective effects of dietary selenium and vitamin C in barium-induced cardiotoxicity.
Cardiovascular Diseases
Effects of obesity and estradiol on Na+/K+-ATPase and their relevance to cardiovascular diseases.
Lanatoside C Induces G2/M Cell Cycle Arrest and Suppresses Cancer Cell Growth by Attenuating MAPK, Wnt, JAK-STAT, and PI3K/AKT/mTOR Signaling Pathways.
Recessive inheritance of a high number of sodium pump sites.
Regulation of Na+/K+-ATPase by Estradiol and IGF-1 in Cardio-Metabolic Diseases.
Cataract
AKT activation promotes PTEN hamartoma tumor syndrome-associated cataract development.
Aldose reductase and its inhibition in the control of diabetic complications.
Extracellular matrix and Na+,K+-ATPase in human corneas following cataract surgery: comparison with bullous keratopathy and Fuchs' dystrophy corneas.
In vitro production of steroid cataract in bovine lens. Part II: measurement of sodium-potassium adenosine triphosphatase activity.
Lenticular rubidium uptake and plasma renin activity in weanling cataract-prone salt-sensitive rats.
Oxidation and cataract.
Prevention of tubulin/aldose reductase association delays the development of pathological complications in diabetic rats.
Sodium pump inhibition and regional expression of sodium pump alpha-isoforms in lens.
Studies on cataractogenesis in humans and in rats with alloxan-induced diabetes. I. Cation transport and sodium-potassium-dependent ATPase.
The effects of digitalis-like compounds on rat lenses.
Topical nerve growth factor attenuates streptozotocin-induced diabetic cataracts via polyol pathway inhibition and Na+/K+-ATPase upregulation.
Cerebellar Ataxia
Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation.
ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.
Functional consequences of the CAPOS mutation E818K of Na+,K+-ATPase.
The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management.
The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence.
Cerebral Hemorrhage
Analysis of amplicon-based NGS data from neurological disease gene panels: a new method for allele drop-out management.
Cerebral Infarction
Brain damage related to hemorrhagic transformation following cerebral ischemia and the role of K ATP channels.
Chemical and Drug Induced Liver Injury
[Biochemical mechanisms of the effect of prostaglandin E2 on the effect of parenteral nitrogenous nutrition]
[Effect of Arnica montana tincture on some hydrolytic enzyme activities of rat liver in experimental toxic hepatitis]
Cholecystitis
[Comparative characteristics of adenosine triphosphatase activity in the erythrocytes of patients with acute and chronic liver diseases, chronic cholecystitis and in HBs antigen carriers]
Cholera
Angiotensin II AT1 receptor/signaling mechanisms in the biphasic effect of the peptide on proximal tubular Na+,K+-ATPase.
Cholera toxin increases Na+/K+-ATPase activity in the RN22 Schwann cell line.
Experimental cholera in the rabbit intestinal loop: fluid accumulation and sodium pump inhibition.
Gangliosides modulate sodium transport in cultured toad kidney epithelia.
Sodium-potassium stimulated adenosine triphosphatase of the small intestine of man: studies in cholera and other diarrheal diseases.
The activation of rabbit intestinal adenylate cyclase by cholera toxin.
Cholestasis
A gene encoding a P-type ATPase mutated in two forms of hereditary cholestasis.
Assessment of Adenosine Triphosphatase Phospholipid Transporting 8B1 (ATP8B1) Function in Patients With Cholestasis With ATP8B1 Deficiency by Using Peripheral Blood Monocyte-Derived Macrophages.
Effect of alpha-asarone and a derivative on lipids, bile flow and Na+/K+-ATPase in ethinyl estradiol-induced cholestasis in the rat.
Intravenous fish oil emulsion attenuates total parenteral nutrition-induced cholestasis in newborn piglets.
Modulation by S-adenosyl-L-methionine of hepatic Na+,K+-ATPase, membrane fluidity, and bile flow in rats with ethinyl estradiol-induced cholestasis.
Role of Na+/K(+)-ATPase in Natriuretic Effect of Prolactin in a Model of Cholestasis of Pregnancy.
Significant increase of Kuppfer cells associated with loss of Na+,K+-ATPase activity in rat hepatic allograft rejection.
The respective roles of membrane cholesterol and of sodium potassium adenosine triphosphatase in the pathogenesis of lithocholate-induced cholestasis.
Cholestasis, Intrahepatic
Assessment of Adenosine Triphosphatase Phospholipid Transporting 8B1 (ATP8B1) Function in Patients With Cholestasis With ATP8B1 Deficiency by Using Peripheral Blood Monocyte-Derived Macrophages.
Autoimmune BSEP Disease: Disease Recurrence After Liver Transplantation for Progressive Familial Intrahepatic Cholestasis.
Indel in the FIC1/ATP8B1 gene-a novel rare type of mutation associated with benign recurrent intrahepatic cholestasis.
Mutation Analysis and Disease Features at Presentation in a Multi-Center Cohort of Children With Monogenic Cholestasis.
The Drosophila melanogaster Phospholipid Flippase dATP8B Is Required for Odorant Receptor Function.
The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease.
Chondroma
Enzyme histochemical study on bone tumors.
Chondrosarcoma
Contribution to the knowledge of the fine structure of chondrosarcoma of bone. With a note on the localization of alkaline phosphatase and "ATPase".
Enzyme histochemical study on bone tumors.
Chorea
A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients.
Colitis
Regional intestinal adaptations in Na+,K+-ATPase in experimental colitis and the contrasting effects of interferon-gamma.
Colonic Neoplasms
Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways.
Cardiotonic Steroids-Mediated Targeting of the Na(+)/K(+)-ATPase to Combat Chemoresistant Cancers.
Immunohistochemical localization of sodium-potassium-stimulated adenosine triphosphatase and carbonic anhydrase in human colon and colonic neoplasms.
Polyamines secreted by cancer cells possibly account for the impairment of the human erythrocyte sodium pump activity.
Colorectal Neoplasms
FXYD6 Regulates Chemosensitivity by Mediating the Expression of Na+/K+-ATPase ?1 and Affecting Cell Autophagy and Apoptosis in Colorectal Cancer.
Interaction of Mat-8 (FXYD-3) with Na+/K+-ATPase in colorectal cancer cells.
Coma
Inhibition of rat brain Na+,K+-ATPase activity by serum from patients with fulminant hepatic failure.
Recurrent coma and fever in familial hemiplegic migraine type 2. A prospective 15-year follow-up of a large family with a novel ATP1A2 mutation.
Thermal acclimation alters Na+/K+-ATPase activity in a tissue-specific manner in Drosophila melanogaster.
Confusion
Acute encephalopathy in familial hemiplegic migraine with ATP1A2 mutation.
Early Treatment in Acute Severe Encephalopathy Caused by ATP1A2 Mutation of Familial Hemiplegic Migraine Type 2: Case Report and Literature Review.
Erythrocyte sodium pump activity in human obesity.
Contracture
Calpain-mediated impairment of Na+/K+-ATPase activity during early reperfusion contributes to cell death after myocardial ischemia.
Enhancement of cardiac actions of ouabain and its binding to Na+, K+-adenosine triphosphatase by increased sodium influx in isolated guinea-pig heart.
Relationship between the potentiation of potassium-induced contracture of cardiac muscle by four cardenolides and their inhibitory effects on the sodium potassium activated adenosine triphosphatase of brain.
Role of the sodium-calcium exchange mechanism and the effect of magnesium on sodium-free and high-potassium contractures in pregnant human myometrium.
Corneal Diseases
Human corneal endothelial cell expression of Na+,K+-adenosine triphosphatase isoforms.
Corneal Edema
Human corneal endothelial cell expression of Na+,K+-adenosine triphosphatase isoforms.
Coronary Artery Disease
Decreased Na+/K+-ATPase Activity and Altered Susceptibility to Peroxidation and Lipid Composition in the Erythrocytes of Metabolic Syndrome Patients with Coronary Artery Disease.
Increased membrane lipid peroxidation and decreased Na+/K+-ATPase activity in erythrocytes of patients with stable coronary artery disease.
Coronavirus Infections
Coronavirus interactions with the cellular autophagy machinery.
Cough
Regulation of cough by neuronal Na(+)-K(+) ATPases.
Selective expression of a sodium pump isozyme by cough receptors and evidence for its essential role in regulating cough.
COVID-19
Coronavirus interactions with the cellular autophagy machinery.
Hypotheses about sub-optimal hydration in the weeks before coronavirus disease (COVID-19) as a risk factor for dying from COVID-19.
Na+/K+-ATPase as a Target of Cardiac Glycosides for the Treatment of SARS-CoV-2 Infection.
Craniocerebral Trauma
Exploring Neuronal Vulnerability to Head Trauma Using a Whole Exome Approach.
Severe episodic neurological deficits and permanent mental retardation in a child with a novel FHM2 ATP1A2 mutation.
The prognostic value of the brain sodium-potassium ATPase enzyme concentration in head injury.
Cushing Syndrome
The human leucocyte sodium pump in Cushing's syndrome.
Cystic Fibrosis
Chloride turnover and ion-transporting activities of yolk-sac preparations (yolk balls) separated from Mozambique tilapia embryos and incubated in freshwater and seawater.
Cortisol regulates insulin-like growth-factor binding protein (igfbp) gene expression in Atlantic salmon parr.
Dynamics of Gene Expression Responses for Ion Transport Proteins and Aquaporins in the Gill of a Euryhaline Pupfish during Freshwater and High-Salinity Acclimation.
Functional classification of mitochondrion-rich cells in euryhaline Mozambique tilapia (Oreochromis mossambicus) embryos, by means of triple immunofluorescence staining for Na+/K+-ATPase, Na+/K+/2Cl- cotransporter and CFTR anion channel.
Gene expression after freshwater transfer in gills and opercular epithelia of killifish: insight into divergent mechanisms of ion transport.
Genome-wide analysis of MicroRNA-messenger RNA interactome in ex-vivo gill filaments, Anguilla japonica.
Influence of salinity on the localization of Na+/K+-ATPase, Na+/K+/2Cl- cotransporter (NKCC) and CFTR anion channel in chloride cells of the Hawaiian goby (Stenogobius hawaiiensis).
Regulation of Cl- Electrolyte Permeability in Epithelia by Active Traditional Chinese Medicine Monomers for Diarrhea.
Short- and long-term low-salinity acclimation effects on the branchial and intestinal gene expression in the European seabass (Dicentrarchus labrax).
Systemic versus tissue-level prolactin signaling in a teleost during a tidal cycle.
The effect of environmental salinity on the protein expression of Na+/K+-ATPase, Na+/K+/2Cl- cotransporter, cystic fibrosis transmembrane conductance regulator, anion exchanger 1, and chloride channel 3 in gills of a euryhaline teleost, Tetraodon nigroviridis.
The effects of transfer from steady-state to tidally-changing salinities on plasma and branchial osmoregulatory variables in adult Mozambique tilapia.
Transepithelial Fluid and Salt Re-Absorption Regulated by cGK2 Signals.
Cysts
A role for Na/K adenosine triphosphatase in the pathogenesis of cyst formation in experimental polycystic kidney disease.
Congenital murine polycystic kidney disease. II. Pathogenesis of tubular cyst formation.
Effect of antihydatid drugs on carbohydrate metabolism of metacestode of echinococcus granulosus.
Effects of mebendazole, albendazole, and praziquantel on alkaline phosphatase, acid phosphatase, and adenosine triphosphatase of Echinococcus granulosus cysts harbored in mice.
Sarcocystis fusiformis: some Krebs cycle enzymes in various fractions of sarcocysts of buffalo (Bubalus bubalis).
Triiodothyronine-induced cyst formation in metanephric organ culture: the role of increased Na-K-adenosine triphosphatase activity.
[Seasonal changes in the adenosine triphosphatase activity in the germinal cysts of the testis of the common frog Rana temporaria. An enzyme histochemical study]
[Ultrastructural localization of alkaline phosphatase and ATP-ase in cyst stages of Sarcocystis tenella (Sporozoa, Coccidia) parasitic in the esophagus of sheep (author's transl)]
Cytochrome-c Oxidase Deficiency
Mitochondrial DNA mutations in Leigh syndrome and their phylogenetic implications.
Deficiency Diseases
Menkes disease diagnosed by a novel ATP7A frameshift mutation in a patient with infantile spasms-a case report.
Dehydration
An hypothesis on the consolidation and PGE1-induced deconsolidation of a platelet plug.
Solute effects on the sodium pump. An evaluation of the osmotic dehydration hypothesis.
Dementia
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase.
Demyelinating Diseases
Potential implications of Helicobacter pylori-related neutrophil-activating protein.
Quercetin treatment regulates the Na+,K+-ATPase activity, peripheral cholinergic enzymes, and oxidative stress in a rat model of demyelination.
Dengue
NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication.
Dermatitis, Contact
Langerhans cells in contact dermatitis of the guinea pig.
Diabetes Complications
Aldose reductase and its inhibition in the control of diabetic complications.
Modifications induced by diabetes on the physicochemical and functional properties of erythrocyte plasma membrane.
NO levels in diabetes mellitus: Effects of l-NAME and insulin on LCAT, Na(+)/K(+) ATPase activity and lipid profile.
Diabetes Mellitus
Effect of streptozotocin-induced diabetes on rat liver Na+/K+-ATPase.
Effects of proinsulin C-peptide on nitric oxide, microvascular blood flow and erythrocyte Na+,K+-ATPase activity in diabetes mellitus type I.
Endogenous sodium pump inhibitors, diabetes mellitus and preeclampsia Preliminary observations and a hypothesis.
Impairment of sodium pump and Na/H exchanger in erythrocytes from non-insulin dependent diabetes mellitus patients: effect of tea catechins.
NO levels in diabetes mellitus: Effects of l-NAME and insulin on LCAT, Na(+)/K(+) ATPase activity and lipid profile.
Prevention of tubulin/aldose reductase association delays the development of pathological complications in diabetic rats.
Small intestinal Na+,K+-adenosine triphosphatase activity and gene expression in experimental diabetes mellitus.
Sorbitol, myo-inositol and sodium-potassium ATPase in diabetic peripheral nerve.
[Tian-shou liquor on activity of cell membrane and energy metabolism in diabetes mellitus]
Diabetes Mellitus, Experimental
Abnormal membrane fluidity and acetylcholinesterase activity in erythrocytes from insulin-dependent diabetic patients.
Effects of streptozotocin diabetes and insulin treatment on myocardial sodium pump and contractility of the rat heart.
Impaired rat sciatic nerve sodium-potassium adenosine triphosphatase in acute streptozocin diabetes and its correction by dietary myo-inositol supplementation.
Na+,K+-ATPase and Mg2+-ATPase activities in different regions of rat brain during alloxan diabetes.
Reduced glomerular sodium/potassium adenosine triphosphatase activity in acute streptozocin diabetes and its prevention by oral sorbinil.
Diabetes Mellitus, Type 1
A study on human umbilical cord endothelial cells: functional modifications induced by plasma from insulin-dependent diabetes mellitus patients.
Influence of low density lipoprotein from insulin-dependent diabetic patients on platelet functions.
Modifications induced by insulin-dependent diabetes mellitus on human placental Na+/K+-adenosine triphosphatase.
Regulation of the inducible nitric oxide synthase and sodium pump in type 1 diabetes.
Sialic acid, diabetes, and aging: a study on the erythrocyte membrane.
Diabetes Mellitus, Type 2
Association of sick sinus syndrome with hyperinsulinemia and insulin resistance in patients with non-insulin-dependent diabetes mellitus: report of four cases.
Reduction of erythrocyte (Na(+)-K+) ATPase activities in non-insulin-dependent diabetic patients with hyperkalemia.
Sialic acid, diabetes, and aging: a study on the erythrocyte membrane.
Diabetic Neuropathies
Accumulation of sorbitol in the sciatic nerve modulates circadian properties of diabetes-induced neuropathic pain hypersensitivity in a diabetic mouse model.
Effect of pre-germinated brown rice intake on diabetic neuropathy in streptozotocin-induced diabetic rats.
Endoneurial ATPase activity in Tangier disease and other peripheral neuropathies.
Erythropoietin: A potential drug in the management of diabetic neuropathy.
Genetic and environmental regulation of Na/K adenosine triphosphatase activity in diabetic patients.
Metabolic correction in the management of diabetic peripheral neuropathy: improving clinical results beyond symptom control.
Platelet sodium and potassium ATPase [corrected] activity and noradrenaline efflux rate in relation to autonomic and peripheral nerve function in insulin-dependent diabetic patients.
Down Syndrome
Erythrocyte membrane cation carrier in Down syndrome.
Drug Resistant Epilepsy
A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients.
Duodenal Ulcer
[Prognostic factors of the speed of cicatrization in duodenal ulcer. Controlled trial of omeprazole versus ranitidine]
Dystonia
A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients.
Abnormal high-frequency burst firing of cerebellar neurons in rapid-onset dystonia-parkinsonism.
Cellular function and pathological role of ATP13A2 and related P-type transport ATPases in Parkinson's disease and other neurological disorders.
Genome-wide screen for modifiers of Na + /K + ATPase alleles identifies critical genetic loci.
Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump.
Mutations Phe785Leu and Thr618Met in Na+,K+-ATPase, associated with familial rapid-onset dystonia parkinsonism, interfere with Na+ interaction by distinct mechanisms.
Rescue of Na+ Affinity in Aspartate-928 Mutants of Na+,K+-ATPase by Secondary Mutation of Glutamate-314.
The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations.
Dystonic Disorders
Alternative Approaches to Modeling Hereditary Dystonias.
Striatal dopaminergic dysregulation and dystonia-like movements induced by sensorimotor stress in a pharmacological mouse model of rapid-onset dystonia-parkinsonism.
Eczema
[Adenosine triphosphoric acid content and adenosine triphosphatase activity in eczema]
Embolism
Microsphere embolism-induced changes in noradrenaline uptake of the cerebral cortex in rats.
Encephalitis, Tick-Borne
[Change in Na+,K+-ATPase activity during reproduction of the tick-borne encephalitis virus in SPEV cell culture]
Encephalomyelitis, Autoimmune, Experimental
Localization of adenosine triphosphatase activity of the endothelia in chronic relapsing experimental allergic encephalomyelitis.
Endolymphatic Hydrops
Na+,K+-ATPase and Ca2+-ATPase activities in the cochlear lateral wall following surgical induction of hydrops.
Endometrial Neoplasms
Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a prognostic factor in human endometrial carcinoma.
Eosinophilic Granuloma
Langerhans' cells and macrophages in eosinophilic granuloma. An enzyme-histochemical, enzyme-cytochemical, and ultrastructural study.
Epilepsies, Partial
Astroglial contribution in human temporal lobe epilepsy: K+ activation of Na+,K+-ATPase in bulk isolated glial cells and synaptosomes.
Contribution of Na+,K(+)-ATPase to focal epilepsy: a brief review.
Epilepsy
A novel ATP1A2 gene mutation in familial hemiplegic migraine and epilepsy.
A Novel ATP1A2 Gene Variant Associated With Pure Sporadic Hemiplegic Migraine Improved After Patent Foramen Ovale Closure: A Case Report.
A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients.
A Wide Clinical Phenotype Spectrum in Patients With ATP1A2 Mutations.
An Infant With Epilepsy and Recurrent Hemiplegia due to Compound Heterozygous Variants in ATP1A2.
Analysis of chromosome 1 microsatellite markers and the FHM2-ATP1A2 gene mutations in migraine pedigrees.
Astroglial contribution in human temporal lobe epilepsy: K+ activation of Na+,K+-ATPase in bulk isolated glial cells and synaptosomes.
Biphasic neurovascular changes in prolonged migraine aura in familial hemiplegic migraine type 2.
Characteristics of cortical spreading depression and c-Fos expression in transgenic mice having a mutation associated with familial hemiplegic migraine 2.
Early onset severe ATP1A2 epileptic encephalopathy: Clinical characteristics and underlying mutations.
Epilepsy as part of the phenotype associated with ATP1A2 mutations.
Epilepsy in hemiplegic migraine: Genetic mutations and clinical implications.
Epilepsy in patients with familial hemiplegic migraine.
Familial hemiplegic migraine mutations affect Na,K-ATPase domain interactions.
Familial Hemiplegic Migraine With Asymmetric Encephalopathy Secondary to ATP1A2 Mutation: A Case Series.
Functional characterization of a novel C-terminal ATP1A2 mutation causing hemiplegic migraine and epilepsy.
Functional correlation of ATP1A2 mutations with phenotypic spectrum: from pure hemiplegic migraine to its variant forms.
Functional effects of Na+,K+-ATPase gene mutations.
Genetic effects of ATP1A2 in familial hemiplegic migraine type II and animal models.
Haplotype-based systematic association studies of ATP1A2 in migraine with aura.
In vitro studies of the influence of glutamatergic agonists on the Na+,K+-ATPase and K+-p-nitrophenylphosphatase activities in the hippocampus and frontal cortex of rats.
Kinetic alterations due to a missense mutation in the Na,K-ATPase alpha2 subunit cause familial hemiplegic migraine type 2.
Migraine and epilepsy: A focus on overlapping clinical, pathophysiological, molecular, and therapeutic aspects.
Migraine in the era of precision medicine.
Mitochondrial disorders.
Na+,K+-ATPase: structure, function, and interactions with drugs.
Neural dysfunction and neurodegeneration in Drosophila Na+/K+ ATPase alpha subunit mutants.
Neurovascular changes in prolonged migraine aura in FHM with a novel ATP1A2 gene mutation.
New CACNA1A deletions are associated to migraine phenotypes.
Novel and de novo mutations in pediatric refractory epilepsy.
Opening of the blood-brain barrier preceding cortical edema in a severe attack of FHM type II.
Prophylactically administered phenytoin. Effects on the development of chronic cobalt-induced epilepsy in the cat.
Regional distributions of hippocampal Na+,K(+)-ATPase, cytochrome oxidase, and total protein in temporal lobe epilepsy.
Relationship between susceptibility to DMCM-induced generalized motor convulsions and low-affinity [3H]-ouabain binding in membranes in rat brain.
Severe attacks of familial hemiplegic migraine, childhood epilepsy and ATP1A2 mutation.
Shared mechanisms of epilepsy, migraine and affective disorders.
Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks.
The CACNA1A and ATP1A2 genes are not involved in dominantly inherited migraine with aura.
The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine: A clinical and genetic study in Finnish migraine families.
The genetic relationship between epilepsy and hemiplegic migraine.
The kinetics of non-synaptically triggered acute excitotoxic responses in the central nervous system observed using intrinsic optical signals.
Update on the genetics of migraine.
[Genetics of migraine]
Epilepsy, Benign Neonatal
Genetics of the epilepsies.
Novel mutations in the Na+, K+-ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions.
Epilepsy, Generalized
Common variants of ATP1A3 but not ATP1A2 are associated with Chinese genetic generalized epilepsies.
Epilepsy, Temporal Lobe
Astroglial contribution in human temporal lobe epilepsy: K+ activation of Na+,K+-ATPase in bulk isolated glial cells and synaptosomes.
Regional distributions of hippocampal Na+,K(+)-ATPase, cytochrome oxidase, and total protein in temporal lobe epilepsy.
Esophageal Squamous Cell Carcinoma
Effects of SLC31A1 and ATP7B polymorphisms on platinum resistance in patients with esophageal squamous cell carcinoma receiving neoadjuvant chemoradiotherapy.
Expression of ATP7A in esophageal squamous cell carcinoma (ESCC) and its clinical significance.
Esophagitis
Regulation of Na/H exchanger-1 in gastroesophageal reflux disease: possible interaction of histamine receptor.
Esophagitis, Peptic
Fulminant hepatic failure related to omeprazole.
Essential Hypertension
A plasma inhibitor of sodium and potassium activated adenosine triphosphatase in patients with essential hypertension.
Abnormal leucocyte sodium transport in Chinese patients with essential hypertension and their normotensive offsprings.
An increase in a circulating inhibitor of Na+,K+-dependent ATPase: a possible link between salt intake and the development of essential hypertension.
Assay of a circulating sodium pump inhibitor in patients with essential hypertension and normotensive subjects.
Blood pressure in essential hypertension correlates with the concentration of a circulating inhibitor of the sodium pump.
Digibind Reverses Inhibition of Cellular rb+ Uptake Caused by Endogenous Sodium Pump Inhibitors Present in Serum and Placenta of Women With Preeclampsia.
Digitalis-like factor and digoxin-like immunoreactive factor in diabetic women with preeclampsia, transient hypertension of pregnancy, and normotensive pregnancy.
Effect of the calcium antagonist verapamil on human leucocyte sodium transport in vitro.
Effects of changes in dietary sodium intake on normotensive subjects with and without a genetic predisposition to essential hypertension.
Effects of lead and a low-molecular-weight endogenous plasma inhibitor on the kinetics of sodium-potassium-activated adenosine triphosphatase and potassium-activated p-nitrophenylphosphatase.
Endogenous digitalis-like factors.
Erythrocyte and plasma Ca2+, Mg2+ and cell membrane adenosine triphosphatase activity in patients with essential hypertension.
Erythrocyte calcium-stimulated, magnesium-activated adenosine 5'-triphosphatase activity in essential hypertension.
Erythrocyte membrane ouabain-sensitive Na+, K(+)-ATPase of hypertensive Nigerians.
Forearm vasoconstrictor response to ouabain: studies in patients with mild and moderate essential hypertension.
Genetic and ethnic influences on the distribution of sodium and potassium in normotensive and hypertensive subjects.
Humoral sodium transport inhibitor in acute volume expansion and low renin hypertension.
Increased concentrations of a circulating sodium pump inhibitor in essential hypertension and uraemia and its partial purification from haemofiltrate.
Kinetics of the human leucocyte Na(+)-H+ antiport in essential hypertension.
Low-concentration ouabain does not inhibit noradrenaline-induced contraction of human resistance arteries.
Maximum binding of ouabain to erythrocytes in relation to a family history of essential hypertension, sodium balance and body weight in normotensive children.
Measurement by bioluminescence technique of erythrocyte membrane Na+,K+-ATPase activity in hypertensive patients.
Observations on the "cascade" of Na-K-ATPase inhibitory and digoxin-like immunoreactive material in human urine: possible relevance to essential hypertension.
Ouabain-like and non-ouabain-like factors in plasma of patients with essential hypertension.
Ouabainlike Na+,K+-ATPase inhibitor in the plasma of normotensive and hypertensive humans and rats.
Partial purification and properties of a plasma ouabain-like inhibitor of Na+, K+-ATPase in patients with essential hypertension.
Plasma endogenous sodium pump inhibitor in essential hypertension.
Plasma sodium pump inhibitor in essential hypertension and normotensive subjects with hypertensive heredity.
Platelet and erythrocyte Mg2+, Ca2+, Na+, K+ and cell membrane adenosine triphosphatase activity in essential hypertension in blacks.
Predominance of high molecular weight plasma Na(+)-K(+)-ATPase inhibitor in essential hypertension.
Raised sodium pump activity and a circulating sodium transport inhibitor demonstrated on red blood cells of patients with untreated essential hypertension: correlation of pump activity with potassium permeability.
Red blood cell Na+,K+-ATPase in men with newly diagnosed or previously treated essential hypertension.
Reduced number of erythrocyte sodium pump units in essential hypertension.
Regulation of sodium/potassium ATPase activity: impact on salt balance and vascular contractility.
Relation of sodium-potassium adenosine triphosphatase inhibitor to sympathetic nervous system during salt-loading in essential hypertension.
Relationship between the sympathetic nervous system and sodium potassium adenosine triphosphatase inhibitor in salt-sensitive patients with essential hypertension.
Role of a natriuretic factor in essential hypertension: an hypothesis.
Sodium pump inhibitor in the serum of patients with essential hypertension and its partial purification from hemofiltrate.
The effect of ouabain on pressor responses to infused noradrenaline in patients with essential hypertension.
The role of a humoral Na+,K+-ATPase inhibitor in regulating precapillary vessel tone.
The sodium pump and energy regulation: some new aspects for essential hypertension, diabetes II and severe overweight.
The sodium pump in hypertension.
[(NA++K+)-ATPase inhibitor from bovine hypothalamus]
[Association of the polymorphisms of sodium transport related genes with essential hypertension]
[Comparison of extra renal potassium management in hypertensive, diabetic and normal subjects]
Facial Paralysis
Impaired Ranvier node sodium-potassium adenosine triphosphatase may induce facial palsy.
Fibroma
Enzyme histochemical study on bone tumors.
Foramen Ovale, Patent
A Novel ATP1A2 Gene Variant Associated With Pure Sporadic Hemiplegic Migraine Improved After Patent Foramen Ovale Closure: A Case Report.
Friedreich Ataxia
Mitochondria and degenerative disorders.
Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders--Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy.
galactokinase deficiency
Suckling rat brain regional distribution of Na+,K+-atpase activity in the in vitro galactosaemia: the effect of L-cysteine and glutathione.
Galactosemias
Suckling rat brain regional distribution of Na+,K+-atpase activity in the in vitro galactosaemia: the effect of L-cysteine and glutathione.
Gallstones
Evidence for oxidative stress in the gall bladder mucosa of gall stone patients.
Gangliosidoses
Fluorescence polarization analysis, lipid composition, and Na+, K+-ATPase kinetics of synaptosomal membranes in feline GM1 and GM2 gangliosidosis.
Gangliosidosis, GM1
Fluorescence polarization analysis, lipid composition, and Na+, K+-ATPase kinetics of synaptosomal membranes in feline GM1 and GM2 gangliosidosis.
Gastritis
Analysis of mononuclear cell infiltrate and cytokine production in murine autoimmune gastritis.
Fas/CD95 is required for gastric mucosal damage in autoimmune gastritis.
Interleukin 27 Protects From Gastric Atrophy and Metaplasia During Chronic Autoimmune Gastritis.
Monoclonal antibodies specific for the core protein of the beta-subunit of the gastric proton pump (H+/K+ ATPase). An autoantigen targetted in pernicious anaemia.
Gastritis, Atrophic
Variations of energy metabolism and adenosine triphosphatase activity in gastric mucosa in chronic atrophic gastritis rats with Qi deficiency and blood stasis syndrome and effect of zhiweifangbian capsule.
Gastroenteritis
Natural cardenolides suppress coronaviral replication by downregulating JAK1 via a Na+/K+-ATPase independent proteolysise.
The cardenolide ouabain suppresses coronaviral replication via augmenting a Na+/K+-ATPase-dependent PI3K_PDK1 axis signaling.
Gastroesophageal Reflux
Improving on PPI-based therapy of GORD.
Regulation of Na/H exchanger-1 in gastroesophageal reflux disease: possible interaction of histamine receptor.
Genetic Diseases, Inborn
Mitochondrial G8292A and C8794T mutations in patients with Niemann-Pick disease type C.
Giant Cell Tumors
Enzyme histochemical study on bone tumors.
Glioblastoma
Bufalin inhibits glioblastoma growth by promoting proteasomal degradation of the Na+/K+-ATPase ?1 subunit.
Cardiotonic Steroids-Mediated Targeting of the Na(+)/K(+)-ATPase to Combat Chemoresistant Cancers.
Editorial: on the road to multi-modal and pluri-disciplinary treatment of glioblastomas.
Epi-reevesioside F inhibits Na+/K+-ATPase, causing cytosolic acidification, Bak activation and apoptosis in glioblastoma.
Evaluation of the relationship of erythrocyte membrane Na+/K+-ATPase enzyme activity and tumor response to chemoradiotherapy in patients diagnosed with locally advanced nonsmall cell lung cancer and glioblastoma multiforme.
Inhibition of Na+/K+-ATPase induces hybrid cell death and enhanced sensitivity to chemotherapy in human glioblastoma cells.
Present and potential future adjuvant issues in high-grade astrocytic glioma treatment.
Response of sodium pump to ouabain challenge in human glioblastoma cells in culture.
Spider venom components decrease glioblastoma cell migration and invasion through RhoA-ROCK and Na+/K+-ATPase ?2: potential molecular entities to treat invasive brain cancer.
Targeting ?2 subunit of Na+/K+-ATPase induces glioblastoma cell apoptosis through elevation of intracellular Ca2.
Targeting the alpha 1 subunit of the sodium pump to combat glioblastoma cells.
The sodium pump ?1 subunit regulates bufalin sensitivity of human glioblastoma cells through the p53 signaling pathway.
The sodium pump alpha1 subunit as a potential target to combat apoptosis-resistant glioblastomas.
Update on the effects of the sodium pump ?1 subunit on human glioblastoma: from the laboratory to the clinic.
[The sodium pump could constitute a new target to combat glioblastomas]
Glioma
Alterations of membrane integrity and cellular constituents by arachidonic acid in neuroblastoma and glioma cells.
ATP1A1 Integrates AKT and ERK Signaling via Potential Interaction With Src to Promote Growth and Survival in Glioma Stem Cells.
Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways.
Lithium normalizes elevated intracellular sodium.
Marinobufagenin inhibits glioma growth through sodium pump ?1 subunit and ERK signaling-mediated mitochondrial apoptotic pathway.
Present and potential future adjuvant issues in high-grade astrocytic glioma treatment.
The sodium pump ?1 subunit regulates bufalin sensitivity of human glioblastoma cells through the p53 signaling pathway.
The sodium pump alpha1 subunit as a potential target to combat apoptosis-resistant glioblastomas.
[Distribution of adenosine triphosphatase activity in the culture of cerebral gliomas]
[The sodium pump could constitute a new target to combat glioblastomas]
Glomerulonephritis
Glomerulonephritis and sodium retention: enhancement of Na+/K+-ATPase activity in the collecting duct is shared by rats with puromycin induced nephrotic syndrome and mice with spontaneous lupus-like glomerulonephritis.
[Adenosine triphosphatase activity of erythrocytes in diffuse glomerulonephritis in children]
glucose-6-phosphatase deficiency
Induction of altered hepatic foci in rats by the administration of hypolipidemic peroxisome proliferators alone or following a single dose of diethylnitrosamine.
Glycogen Storage Disease Type I
Induction of altered hepatic foci in rats by the administration of hypolipidemic peroxisome proliferators alone or following a single dose of diethylnitrosamine.
Granuloma
Susceptibility of desert sheep to infection with Schistosoma mansoni of Northern Sudan.
Graves Disease
Enzyme histochemistry and thyroid neoplasia.
[Therapeutic effect and its mechanism exploration on mainly using traditional Chinese medicine of replenishing qi and nourishing yin in treating Graves disease]
Head and Neck Neoplasms
[The cytochemical determination of alpha-glycerophosphate dehydrogenase and adenosine triphosphatase in the peripheral blood lymphocytes of patients with hepatobiliary system pathology]
Hearing Loss
A missense variant of the ATP1A2 gene is associated with a novel phenotype of progressive sensorineural hearing loss associated with migraine.
The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management.
The Drosophila melanogaster Phospholipid Flippase dATP8B Is Required for Odorant Receptor Function.
The Endocannabinoid/Cannabinoid Receptor 2 System Protects Against Cisplatin-Induced Hearing Loss.
Hearing Loss, Sensorineural
A missense variant of the ATP1A2 gene is associated with a novel phenotype of progressive sensorineural hearing loss associated with migraine.
Functional consequences of the CAPOS mutation E818K of Na+,K+-ATPase.
Inhibition of Na+,K+-stimulated ATPase in the cochlea of the guinea pig. A potential cause of disturbed inner ear function in terminal renal failure.
The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence.
Heart Defects, Congenital
Sodium pump reduction correlates with aortic clamp time in pediatric heart surgery.
Heart Diseases
Cardiac Glycosides as Immune System Modulators.
Insect Collections as an Untapped Source of Bioactive Compounds-Fireflies (Coleoptera: Lampyridae) and Cardiotonic Steroids as a Proof of Concept.
Heart Failure
Altered diastolic [Ca2+]i handling in human ventricular myocytes from patients with terminal heart failure.
Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase {alpha}2-isoform in heart failure.
Altered sarco(endo)plasmic reticulum calcium adenosine triphosphatase 2a content: Targets for heart failure therapy.
Antiherpes activity of glucoevatromonoside, a cardenolide isolated from a Brazilian cultivar of Digitalis lanata.
Assist devices fail to reverse patterns of fetal gene expression despite beta-blockers.
Association of chronic congestive heart failure in humans with an intrinsic upregulation in skeletal muscle sarcoplasmic reticulum calcium ion adenosine triphosphatase activity.
Association of depressed myofibrillar adenosine triphosphatase and reduced contractility in experimental heart failure.
Cardenolides: Insights from chemical structure and pharmacological utility.
Cardiac glycoside bufalin blocks cancer cell growth by inhibition of Aurora A and Aurora B activation via PI3K-Akt pathway.
Cardiac Glycosides Activate the Tumor Suppressor and Viral Restriction Factor Promyelocytic Leukemia Protein (PML).
Cardiac Resynchronization and Circulating Markers of Sarcoplasmic Reticulum Calcium Handling and Sudden Death Risk.
Cardiotonic steroid ouabain stimulates steroidogenesis in Leydig cells via the ?3 isoform of the sodium pump.
Cardiotonic steroids on the road to anti-cancer therapy.
Comparison of heart sarcolemmal enzyme activities in normal and cardiomyopathic (UM-X7.1) hamsters.
Digitoxin-induced cytotoxicity in cancer cells is mediated through distinct kinase and interferon signalling networks.
Distribution of sodium and potassium in chronic obstructive pulmonary disease.
Effects of digoxin on cardiac iron content in rat model of iron overload.
Human myocardial adenosine triphosphatase activities in health and heart failure.
Isoform-specific alterations in cardiac and erythrocyte Na+,K+-ATPase activity induced by norepinephrine.
Istaroxime, a stimulator of sarcoplasmic reticulum calcium adenosine triphosphatase isoform 2a activity, as a novel therapeutic approach to heart failure.
Istaroxime: a new luso-inotropic agent for heart failure.
Magnesium treatment of diuretic-induced hyponatremia with a preliminary report of a new aldosterone-antagonist.
Mammalian cardenolides as biomarkers in congestive heart failure.
Marinobufagenin, an endogenous ligand of alpha-1 sodium pump, is a marker of congestive heart failure severity.
Mitigation of myocardial fibrosis by molecular cardiac surgery-mediated gene overexpression.
Myofibrillar adenosine triphosphatase activity in congestive heart failure.
Ouabain potentiates the antimicrobial activity of aminoglycosides against Staphylococcus aureus.
Reduced sodium pump alpha1, alpha3, and beta1-isoform protein levels and Na+,K+-ATPase activity but unchanged Na+-Ca2+ exchanger protein levels in human heart failure.
Regulation of Na+/K+-ATPase by Estradiol and IGF-1 in Cardio-Metabolic Diseases.
Regulation of the cardiac sodium pump.
Role of inositol 1,4,5-trisphosphate receptors in regulating apoptotic signaling and heart failure.
Significance of sodium pump isoforms in digitalis therapy.
Sodium pump isoform expression in heart failure: implication for treatment.
The ?2-isoform of the Na+/K+-ATPase protects against pathological remodeling and ?-adrenergic desensitization after myocardial infarction.
The amino acid composition of actin and myosin and Ca2+-activated myosin adenosine triphosphatase in chronic canine congestive heart failure.
The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction.
[Cancer cell-specific functional relation between Na+,K+-ATPase and volume-regulated anion channel].
Hemiplegia
'Absence of T378N mutation of ATP1A2 gene in five patients with alternating hemiplegia of childhood'.
A long-term follow-up study of 18 patients with sporadic hemiplegic migraine.
A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients.
A novel lethal recognizable polymicrogyric syndrome caused by ATP1A2 homozygous truncating variants.
A novel mutation in the ATP1A2 gene causes alternating hemiplegia of childhood.
A Wide Clinical Phenotype Spectrum in Patients With ATP1A2 Mutations.
Alternating hemiplegia of childhood and a pathogenic variant of ATP1A3: a case report and pathophysiological considerations.
Alternating hemiplegia of childhood or familial hemiplegic migraine? A novel ATP1A2 mutation.
Alternating hemiplegia of childhood: no mutations in the second familial hemiplegic migraine gene ATP1A2.
An Infant With Epilepsy and Recurrent Hemiplegia due to Compound Heterozygous Variants in ATP1A2.
ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.
Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations.
CACNA1A-Linked Hemiplegic Migraine in GLUT 1 Deficiency Syndrome: A Case Report.
Characterization of cognitive deficits in mice with an alternating hemiplegia-linked mutation.
Comparative analysis of alternating hemiplegia of childhood and rapid-onset dystonia-parkinsonism ATP1A3 mutations reveals functional deficits, which do not correlate with disease severity.
De novo ATP1A2 variants in two Chinese children with alternating hemiplegia of childhood upgraded the gene-disease relationship and variant classification: a case report.
Genome-wide screen for modifiers of Na + /K + ATPase alleles identifies critical genetic loci.
Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump.
Knock-in mouse model of alternating hemiplegia of childhood: behavioral and electrophysiologic characterization.
Novel E815K knock-in mouse model of alternating hemiplegia of childhood.
Prolonged hemiplegic episodes in children due to mutations in ATP1A2.
Rescue of Na+ Affinity in Aspartate-928 Mutants of Na+,K+-ATPase by Secondary Mutation of Glutamate-314.
The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence.
Hemoglobinuria
[Activity of adenosine triphosphatase of the erythrocytic membrane in paroxysmal nacturnal hemoglobinuria]
Hepatic Encephalopathy
Inhibition of rat brain Na+,K+-ATPase activity by serum from patients with fulminant hepatic failure.
Hepatitis
Coronavirus interactions with the cellular autophagy machinery.
Sodium transport in red cells of patients with acute viral hepatitis.
[Histochemical studies of the effect of Meritschleri mineral water on the activity of lipase, cytochrome oxidase and adenosine triphosphatase enzymes in the liver in experimental hepatitis]
[Lactate dehydrogenase, glucosephosphate dehydrogenase, glutathione reductase and adenosine triphosphatase activities in the erythrocytes of patients with acute viral hepatitis]
[The activities of acid phosphatase (ACP) and Mg++ adenosine triphosphatase in acute hepatitis with submassive necrosis]
[The cytochemical determination of alpha-glycerophosphate dehydrogenase and adenosine triphosphatase in the peripheral blood lymphocytes of patients with hepatobiliary system pathology]
Hepatitis B
Immune and enzyme histochemical studies of a human hepatocellular carcinoma cell line producing hepatitis B surface antigen.
Hepatitis C
Antigenicity of a recombinant NS3 protein representative of ATPase/helicase domain from hepatitis C virus.
Hepatolenticular Degeneration
A new mutation of Wilson's disease P-type ATPase gene in a patient with cirrhosis and coombs-positive hemolytic anemia.
Adenosine triphosphate-dependent copper transport in human liver.
Adenosine triphosphate-dependent copper transport in isolated rat liver plasma membranes.
Ceruloplasmin in neurodegenerative diseases.
Concordance rates of Wilson's disease phenotype among siblings.
Copper-dependent interaction of dynactin subunit p62 with the N terminus of ATP7B but not ATP7A.
Copper-induced apical trafficking of ATP7B in polarized hepatoma cells provides a mechanism for biliary copper excretion.
Developmental expression of Commd1 in the liver of the Jackson toxic milk mouse.
Diagnosis and phenotypic classification of Wilson disease.
Direct sequencing of mutations in the copper-transporting P-type adenosine triphosphate (ATP7B) gene for diagnosis and pathogenesis of Wilson's disease.
Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B.
Disturbed copper transport in humans. Part 2: mutations of the ATP7B gene lead to Wilson disease (WD).
Diverse Functional Properties of Wilson Disease ATP7B Variants.
Efficacy of zinc supplementation in preventing acute hepatitis in Long-Evans Cinnamon rats.
Gene mutations in Wilson disease in Egyptian children: report on two novel mutations.
Genetic analysis of BIRC4/XIAP as a putative modifier gene of Wilson disease.
Genetically confirmed Wilson disease in a 9-month old boy with elevations of aminotransferases.
High yield heterologous expression of wild-type and mutant Cu+-ATPase (ATP7B, Wilson disease protein) for functional characterization of catalytic activity and serine residues undergoing copper-dependent phosphorylation.
Identification of three novel mutations and a high frequency of the Arg778Leu mutation in Korean patients with Wilson disease.
Isolation and characterization of a human liver cDNA as a candidate gene for Wilson disease.
Late neurological presentations of Wilson disease patients in French population and identification of 8 novel mutations in the ATP7B gene.
Localization of the Wilson's disease protein in human liver.
Mitochondria and degenerative disorders.
Molecular analysis of Wilson disease in Taiwan: identification of one novel mutation and evidence of haplotype-mutation association.
Monozygotic female twins discordant for phenotype of Wilson's disease.
Mutation analysis and characterization of alternative splice variants of the Wilson disease gene ATP7B.
Mutation analysis and the correlation between genotype and phenotype of Arg778Leu mutation in chinese patients with Wilson disease.
Mutational analysis of ATP7B and genotype-phenotype correlation in Japanese with Wilson's disease.
Mutational analysis of ATP7B in Chinese Wilson disease patients.
NMR Characterization of Copper-Binding Domains 4-6 of ATP7B .
Oxidative-phosphorylation defects in liver of patients with Wilson's disease.
P-type ATPase from the cyanobacterium Synechococcus 7942 related to the human Menkes and Wilson disease gene products.
Role of the copper-binding domain in the copper transport function of ATP7B, the P-type ATPase defective in Wilson disease.
Sequence, mapping and disruption of CCC2, a gene that cross-complements the Ca(2+)-sensitive phenotype of csg1 mutants and encodes a P-type ATPase belonging to the Cu(2+)-ATPase subfamily.
Wilson disease and Menkes disease: new handles on heavy-metal transport.
Wilson disease: identification of two novel mutations and clinical correlation in Eastern Chinese patients.
Wilson disease: novel mutations in the ATP7B gene and clinical correlation in Brazilian patients.
[Copper metabolism and genetic disorders].
[Haplotype analysis and possible founder effect at the R778L mutation of the ATP7B gene in Korean patients with Wilson's disease.]
[The onset of psychiatric disorders and Wilson's disease]
Herpes Simplex
Coronavirus interactions with the cellular autophagy machinery.
Solubilization of adenosine triphosphatase associated with herpes simplex virus.
Some properties of the adenosine triphosphatase associated with herpes simplex virus and nuclear membrane of host cells.
The herpes simplex virus type 1 origin-binding protein. sequence-specific activation of adenosine triphosphatase activity by a double-stranded DNA containing box I.
Herpes Zoster
Mesothelial cells: a cellular surrogate for tissue engineering of corneal endothelium.
Ouabain chronic infusion enhances the growth and steroidogenic capacity of rat adrenal zona glomerulosa: the possible involvement of the endothelin system.
Transplanting embryonic stem cells onto damaged human corneal endothelium.
Histiocytoma, Malignant Fibrous
Enzyme histochemical study on bone tumors.
Histiocytosis, Langerhans-Cell
Histiocytosis X cells and Langerhans cells: enzyme histochemical and immunologic similarities.
Homocystinuria
In vitro homocysteine inhibits platelet Na+,K+-ATPase and serum butyrylcholinesterase activities of young rats.
In vivo and in vitro effects of homocysteine on Na+, K+-ATPase activity in parietal, prefrontal and cingulate cortex of young rats.
Huntington Disease
Increased sodium plus potassium adenosine triphosphatase activity in erythrocyte membranes in Huntington's disease.
Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders--Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy.
Hydrops Fetalis
ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.
Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations.
Hyperaldosteronism
Does a digoxin-like substance participate in vascular and pressure control during dietary sodium changes in patients with primary aldosteronism?
Intracellular sodium and potassium concentrations in erythrocytes of patients with primary aldosteronism.
Sodium transport parameters in erythrocytes of patients with primary aldosteronism.
Hypercholesterolemia
Influence of sterols and phospholipids on sarcolemmal and sarcoplasmic reticular cation transporters.
Hyperemia
Na+/K+-ATPase plays a major role in mediating cutaneous thermal hyperemia achieved by local skin heating to 39 ºC.
Reactive Hyperemia Occurs Via Activation of Inwardly Rectifying Potassium Channels and Na+/K+-ATPase in Humans.
Hyperhomocysteinemia
Concurrent folate treatment prevents Na+,K+-ATPase activity inhibition and memory impairments caused by chronic hyperhomocysteinemia during rat development.
Hyperinsulinism
Association of sick sinus syndrome with hyperinsulinemia and insulin resistance in patients with non-insulin-dependent diabetes mellitus: report of four cases.
Criteria for choosing amino acid therapy in acute renal failure.
Diabetes mellitus and hypertension.
Hyperkalemia
Altered fluid, electrolyte and mineral status in tropical disease, with an emphasis on malaria and leptospirosis.
Digoxin-like immunoreactive substance in nonoliguric hyperkalemia of the premature infant.
Frontiers: skeletal muscle sodium pump regulation: a translocation paradigm.
Reduction of erythrocyte (Na(+)-K+) ATPase activities in non-insulin-dependent diabetic patients with hyperkalemia.
The role of a humoral Na+,K+-ATPase inhibitor in regulating precapillary vessel tone.
Hyperlactatemia
Lactate production and measurement in critically ill horses.
Hyperprolactinemia
Role of Na+/K(+)-ATPase in Natriuretic Effect of Prolactin in a Model of Cholestasis of Pregnancy.
Hypersensitivity
A circulating inhibitor of the platelet Na+,K+ adenosine triphosphatase (ATPase) enzyme in allergy.
Antiarrhythmic drug amiodarone displays antifungal activity, induces irregular calcium response and intracellular acidification of Aspergillus niger - Amiodarone targets calcium and pH homeostasis of A. niger.
Familial hemiplegic migraine type 2 does not share hypersensitivity to nitric oxide with common types of migraine.
The relationship between airway hyperreactivity (AHR) and sodium, potassium adenosine triphosphatase (Na+,K+ ATPase) enzyme inhibition.
[Activity of acid and alkaline phosphatases and adenosine triphosphatase in secondary allergy before and after treatment with hydrocortisone]
Hypertension
Abnormalities in the sodium transport as the causative factor for enhanced norepinephrine overflow in the spontaneously hypertensive rat.
Abnormalities of membrane transport in hypertension.
Abnormalities of sodium pump function in hypertension and the role of endogenous cardiotonic steroids.
Acute Na+,K+-ATPase inhibition with bufalin impairs pressure natriuresis in the rat.
Alterations in phenylephrine-induced contractions and the vascular expression of Na+,K+-ATPase in ouabain-induced hypertension.
Altered erythrocyte cation transport related to hypertension or oral contraception.
Altered sodium pump alpha and gamma subunit gene expression in nephron segments from hypertensive rats.
Altered subcellular distribution of Na+,K+-ATPase in proximal tubules in young spontaneously hypertensive rats.
Brain Na+,K+-ATPase isozyme activity and protein expression in ouabain-induced hypertension.
Calcium antagonists in hypertension: relation to abnormal sodium transport.
Cardenolide and bufadienolide ligands of the sodium pump. How they work together in NaCl sensitive hypertension.
Characterization of a Na+/K+-ATPase inhibitor from human plasma: preliminary data.
Chloride in smooth muscle.
Cicletanine reverses vasoconstriction induced by the endogenous sodium pump ligand, marinobufagenin, via a protein kinase C dependent mechanism.
Circulating bufodienolide and cardenolide sodium pump inhibitors in preeclampsia.
Commentary. The sodium pump in cardiovascular muscle in hypertension: whose hypothesis?
Demonstration of a ouabainlike plasma compound in hypertension prone and hypertension resistant rats.
Dietary salt, intracellular ion homeostasis and hypertension secondary to early-stage kidney disease.
Dietary Sodium Restriction and Association with Urinary Marinobufagenin, Blood Pressure, and Aortic Stiffness.
Differential regulation of the sodium pump alpha-subunit isoform gene by ouabain and digoxin in tissues of rats.
Digitalis-like factor response to hyperinsulinemia accompanying a euglycemic hyperinsulinemic clamp or oral glucose tolerance test.
Digitalis-like factor response to hyperinsulinemia in human pregnancy, a model of insulin resistance.
Does a digoxin-like substance participate in vascular and pressure control during dietary sodium changes in patients with primary aldosteronism?
Downstream shift in sodium pump activity along the nephron during acute hypertension.
Dual effect of polyphenolic compounds on cardiac Na+/K+-ATPase during development and persistence of hypertension in rats.
Effect of ageing and hypertension on endothelial modulation of ouabain-induced contraction and sodium pump activity in the rat aorta.
Effect of dietary sodium on the Na-K ATPase inhibitor in patients with essential hypertension.
Effect of local infusion of ouabain on human forearm vascular resistance and on response to potassium, verapamil and sodium nitroprusside.
Effect of maturation on renal Na+/K+-atpase and its susceptibility to nitric oxide-deficient hypertension in rats.
Effect of mechanical strain on expression of Na+,K+-ATPase alpha subunits in rat aortic smooth muscle cells.
Effect of ouabain on the pathogenesis of hypertension in rats.
Effects of changes in sodium balance on leucocyte sodium transport: qualitative differences in normotensive offspring of hypertensives and matched controls.
Effects of lead and natriuretic hormone on kinetics of sodium-potassium-activated adenosine triphosphatase: possible relevance to hypertension.
Effects of manipulation of sodium balance on erythrocyte sodium transport.
Effects of ouabain on adrenergic neurotransmission in spontaneously hypertensive rats.
Endogenous cardiac glycosidelike compounds.
Endogenous cardiac glycosides: hormones using the sodium pump as signal transducer.
Endogenous cardiotonic steroids and differential patterns of sodium pump inhibition in NaCl-loaded salt-sensitive and normotensive rats.
Endogenous cardiotonic steroids.
Endogenous digitalislike substance in an adult population in Japan.
Endogenous ligand of alpha(1) sodium pump, marinobufagenin, is a novel mediator of sodium chloride--dependent hypertension.
Endogenous sodium pump inhibition: current status and therapeutic opportunities.
Epidemiological evidence associating dietary calcium and calcium metabolism with blood pressure.
Erythrocyte ghost Na+,K+-ATPase and blood pressure.
Erythrocyte sodium transport and blood pressure in white subjects.
Erythrocyte sodium transport and the probability of having hypertension.
Evidence for a circulating endogenous Na+-K+ pump inhibitor in low-renin hypertension.
Expression of sodium pump isoforms and other sodium or calcium ion transporters in the heart of hypertensive patients.
Facilitatory effects of ouabain and digitalis-like substance on adrenergic transmission in hypertension.
Function of the sodium pump in arterial smooth muscle in experimental hypertension: role of pressure.
Functional differences in blood vessels determined from studies with calcium-channel blockers. Functional changes in forearm resistance vessels of men with primary hypertension.
Further biochemical characterization of an Na+ pump inhibitor purified from human urine.
Genetic and genomic evidence for an important role of the Na+/H+ exchanger 3 in blood pressure regulation and angiotensin II-induced hypertension.
Genetic determinants of emotionality and stress response in AcB/BcA recombinant congenic mice and in silico evidence of convergence with cardiovascular candidate genes.
Humoral sodium transport inhibitor in acute volume expansion and low renin hypertension.
Hypertension and inhibition of the sodium pump: a strong link but in which chain?
Hypertension-linked mutation in the adducin alpha-subunit leads to higher AP2-mu2 phosphorylation and impaired Na+,K+-ATPase trafficking in response to GPCR signals and intracellular sodium.
Hypothetical mechanism of sodium pump regulation by estradiol under primary hypertension.
In ability of Na+,K+-ATPase inhibitor to cause hypertension in sodium-loaded or deoxycorticosterone-treated one kidney rats.
Increased activity of digoxin-like substance in low-renin hypertension in acromegaly.
Inhibitors of Na-K-ATPase in human urine: effects of ouabain-like factors and of vanadium-diascorbate on calcium mobilization in rat vascular smooth muscle cells: comparison with the effects of ouabain, angiotensin II, and arginine-vasopressin.
Intracellular sodium and potassium concentrations in erythrocytes of patients with primary aldosteronism.
Isolation and characterization of a specific endogenous Na+,K+-ATPase inhibitor from bovine adrenal.
Lack of effect of acute alcohol ingestion on erythrocyte Na+, K+ -ATPase activity or passive sodium uptake in vivo in man.
Lenticular rubidium uptake and plasma renin activity in weanling cataract-prone salt-sensitive rats.
Leucocyte electrolytes and sodium efflux rate constants in the hypertension of pre-eclampsia.
Leucocyte membrane sodium transport in normotensive populations: dissociation of abnormalities of sodium efflux from raised blood-pressure.
Leucocyte sodium content and sodium pump activity in overweight and lean hypertensives.
Low-concentration ouabain does not inhibit noradrenaline-induced contraction of human resistance arteries.
Magnesium supplementation prevents the development of alcohol-induced hypertension.
Main results of the ouabain and adducin for Specific Intervention on Sodium in Hypertension Trial (OASIS-HT): a randomized placebo-controlled phase-2 dose-finding study of rostafuroxin.
Marinobufagenin impairs first trimester cytotrophoblast differentiation.
Marinobufagenin may mediate the impact of salty diets on left ventricular hypertrophy by disrupting the protective function of coronary microvascular endothelium.
Measurement by bioluminescence technique of erythrocyte membrane Na+,K+-ATPase activity in hypertensive patients.
Mechanism of garlic (Allium sativum) induced reduction of hypertension in 2K-1C rats: a possible mediation of Na/H exchanger isoform-1.
Membrane transport, sodium balance, and blood pressure regulation.
Na+,K+-ATPase activity and responsiveness of vascular smooth muscle to norepinephrine, angiotensin II and calcium ionophore A23187 in guinea pig aortic strips.
Na+/K+-ATPase alpha isoforms expression in stroke-prone spontaneously hypertensive rat heart ventricles: effect of salt loading and lacidipine treatment.
Na+/K+-ATPase regulation in Dahl salt-sensitive and salt-resistant rats.
Natriuretic hormones in low renin hypertension.
New ouabain-conjugated peptide found from phage displayed peptide library.
Observations on the "cascade" of Na-K-ATPase inhibitory and digoxin-like immunoreactive material in human urine: possible relevance to essential hypertension.
Oleic and linoleic acids are active principles in Nigella sativa and stabilize an E(2)P conformation of the Na,K-ATPase. Fatty acids differentially regulate cardiac glycoside interaction with the pump.
Ouabain stimulates endothelin release and expression in human endothelial cells without inhibiting the sodium pump.
Ouabain vasoconstricts human forearm arterioles through alpha-adrenergic stimulation.
Ouabainlike Na+,K+-ATPase inhibitor in the plasma of normotensive and hypertensive humans and rats.
Pharmacologic agents for the in vivo detection of vascular sodium transport defects in hypertension.
Phasic vascular sodium pump changes in deoxycorticosterone-hypertensive rats.
Plasma Na+-K+ ATPase inhibitory activity in normal and hypertensive subjects: relationship to intracellular electrolytes and blood pressure.
Plasma sodium pump inhibitor in essential hypertension and normotensive subjects with hypertensive heredity.
Platelet sodium kinetics, blood pressure and serum urate: aberrations in non-obese men at risk for type 2 diabetes mellitus.
Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study.
Potassium in skeletal muscle in untreated primary hypertension and in chronic renal failure, studied by X-ray fluorescence technique.
Potassium, Na+-K+ pump inhibitor and low-renin hypertension.
PP089. Analytical aspects of marinobufagenin and its applications in the diagnosis of preeclampsia.
Pregnancy induced hypertension and sodium pump function in erythrocytes.
Problems and pitfalls in the isolation of an endogenous Na+, K+-ATPase inhibitor.
Proximal tubule Na transporter responses are the same during acute and chronic hypertension.
Pulmonary arterial hypertension in familial hemiplegic migraine with ATP1A2 channelopathy.
Race, sex, and family history of hypertension and erythrocyte sodium pump [3H]ouabain binding.
Raised sodium pump activity and a circulating sodium transport inhibitor demonstrated on red blood cells of patients with untreated essential hypertension: correlation of pump activity with potassium permeability.
Regulation of blood pressure during long-term ouabain infusion in Long-Evans rats.
Regulation of Na+,K+-ATPase alpha-subunit expression by mechanical strain in aortic smooth muscle cells.
Regulation of Na+/K+-ATPase by Estradiol and IGF-1 in Cardio-Metabolic Diseases.
Regulation of sodium/potassium ATPase activity: impact on salt balance and vascular contractility.
Regulation of the sodium pump in pregnancy-related tissues in preeclampsia.
Relationship of Na-K-ATPase inhibitors to blood-pressure regulation in continuous ambulatory peritoneal dialysis and hemodialysis.
Renal sodium pump regulation in deoxycorticosterone salt hypertension in the rat.
Revealing of endogenous Marinobufagin by an ultra-specific and sensitive UHPLC-MS/MS assay in pregnant women.
Reversal of sodium pump inhibitor induced vascular smooth muscle contraction with digibind. Stoichiometry and its implications.
Reversible inhibition of leucocyte sodium pumps by a circulating serum factor in essential hypertension.
Role of ouabain-like factors and Na-K-ATPase inhibitors in hypertension--some old and recent findings.
Salt and gene expression: evidence for [Na(+)] i/[K (+)] i-mediated signaling pathways.
Salt and hypertension: recent advances and perspectives.
Salt sensitivity in normotensives with family history of hypertension: studies of membrane transport, intracellular electrolytes and alpha 2-adrenergic receptors.
Salt, Na+,K+-ATPase and hypertension.
Sodium pump activity and norepinephrine responsiveness of femoral arterial smooth muscle from DOCA-salt rats.
Sodium pump activity in arteries of Dahl salt-sensitive rats.
Sodium pump activity in arteries of rats with Goldblatt hypertension.
Sodium pump activity in young and adult salt hypertensive Dahl rats.
Sodium pump and Na+/H+ activities in uremic erythrocytes. A microcalorimetric and pH-metric study.
Sodium pump inhibition and regional expression of sodium pump alpha-isoforms in lens.
Sodium transport in erythrocytes: differences between normal children and children with primary and secondary hypertension.
Sodium-potassium pump in low-renin hypertension.
Sodium-potassium-adenosine triphosphatase in nephron segments of spontaneously hypertensive rats.
Species sensitivity of the sodium pump to a circulating ouabain-like inhibitor in acute hypervolemia and DOCA hypertension: comparison with ouabain.
Structure-activity relationships for the hypertensinogenic activity of ouabain: role of the sugar and lactone ring.
Studies on the role of sodium- and potassium-activated adenosine triphosphatase inhibition in the pathogenesis of human hypertension. Changes in vascular and cardiac function following inhibition of the sodium pump in normotensive subjects and effects of calcium entry blockade.
Sustained volume expansion and [Na,K]ATPase inhibition in chronic renal failure.
Sympathetic vasoconstriction as a mechanism of action of ouabain in forearm arterioles of hypertensive patients.
The dilator response to K+ is reduced in the forearm resistance vessels of men with primary hypertension.
The Pressure of Aging.
The role of a humoral Na+,K+-ATPase inhibitor in regulating precapillary vessel tone.
The role of a humoral sodium-potassium pump inhibitor in low-renin hypertension.
The role of chloride on deoxycorticosterone acetate-salt hypertension.
The role of endogenous inhibition of Na-K-ATPase in human hypertension--sodium pump activity as a determinant of peripheral vascular resistance.
The role of sodium-potassium adenosine triphosphatase in the regulation of membrane fluidity of erythrocytes in spontaneously hypertensive rats: an electron paramagnetic resonance investigation.
The role of vascular Na,K-ATPase activity in salt induced hypertension in Dahl rats.
The sodium pump and hypertension: a physiological role for the cardiac glycoside binding site of the Na,K-ATPase.
The sodium pump in hypertension.
Three red cell sodium transport systems in hypertensive and normotensive Utah adults.
Tissue-specific regulation of the sodium pump in DOCA-salt hypertension.
Transactivation of epidermal growth factor receptor in vascular and renal systems in rats with experimental hyperleptinemia: role in leptin-induced hypertension.
Transgenic overexpression of translationally controlled tumor protein induces systemic hypertension via repression of Na+,K+-ATPase.
Two-dimensional, sex-specific autosomal linkage scan of the number of sodium pump sites.
Vascular endothelium as a target for endogenous ouabain: studies on the effect of ouabain on human endothelial cells.
Vascular muscle membrane cation mechanisms and total peripheral resistance.
Vascular smooth muscle membrane potentials in rats with one-kidney, one clip and reduced renal mass-saline hypertension: the influence of a humoral sodium pump inhibitor.
Vascular sodium pump activity kinetics in early and advanced stages of deoxycorticosterone-salt hypertension in rats.
Wistar rats resistant to the hypertensive effects of ouabain exhibit enhanced cardiac vagal activity and elevated plasma levels of calcitonin gene-related peptide.
[(Na + --K + )-dependent adenosine triphosphatase in the renal medulla and cortex of rabbits with ischemic cerebral hypertension]
[A novel hormone found in circulation--endogenous ouabain]
[Changes in the glycolytic pathway in patients with essential arterial hypertension]
[Effect of ouabain on intracellular Ca(2+) concentration in rat vascular smooth muscle cells in vitro].
[Genetic hypertension in the SHR rat and circulating digitalis compounds]
[Hereditary salt sensitivity as a cause of essential hypertension: studies of membrane transport and intracellular electrolytes]
[Is there a relation between the presence in the serum of patients with arterial hypertension of a protein component with molecular weight of 15 kD and the inhibitory effect of the serum on Na,K-ATPase?]
[Physiologic role of the sodium pump. Implications for the study of arterial hypertension]
[Preparation and characterization of polyclonal antibodies against rat sodium pump alpha 2 subunit M1-M2 extra membrane fragment].
Hypertension, Pregnancy-Induced
Endogenous digitalis-like factors.
Modifications induced by plasma of gestational hypertensive women on the Na+/K+-ATPase obtained from human placenta.
Platelet sodium pump and sodium potassium cotransport activity in nonpregnant, normotensive, and hypertensive pregnant women.
Pregnancy induced hypertension and sodium pump function in erythrocytes.
Sodium pump numbers and cation transport of lymphocytes in pregnancy-induced hypertension.
[Ganoderma spores may regulate the levels of mitochondria-related molecular substances in hippocampus of young rats birthed by rats with gestational hypertension]
Hypertension, Renal
Dietary salt, intracellular ion homeostasis and hypertension secondary to early-stage kidney disease.
Hypertension, Renovascular
Measurement by bioluminescence technique of erythrocyte membrane Na+,K+-ATPase activity in hypertensive patients.
Sodium pump activity in arteries of rats with Goldblatt hypertension.
Sodium pump activity in thymocytes of rats with Goldblatt hypertension.
Hyperthyroidism
Abnormalities in the sodium pump of erythrocytes from patients with hyperthyroidism.
Catecholamine and thyroid hormone influence on brown fat Na+, K+-ATPase activity and thermogenesis in the rat.
Changes in acetylcholinesterase, Na+,K+-ATPase, and Mg2+-ATPase activities in the frontal cortex and the hippocampus of hyper- and hypothyroid adult rats.
Effect of thyroid status on the development of the different molecular forms of Na+,K+-ATPase in rat brain.
Effects of oxidative stress on the erythrocyte Na+,K+ ATPase activity in female hyperthyroid patients.
Effects of thyroid hormone on sodium pump sites, sodium content, and contractile responses to cardiac glycosides in cultured chick ventricular cells.
Erythrocyte ouabain binding in patients receiving thyroxine.
Erythrocyte sodium fluxes, ouabain binding sites, and Na+,K(+)-ATPase activity in hyperthyroidism.
Induction of the ATP-dependent proteolytic system in guinea pig reticulocyte lysates by triiodothyronine.
Ion flux and Na+,K+-ATPase activity of erythrocytes and leucocytes in thyroid disease.
Na+K+ATPase activity and ouabain binding sites in erythrocytes in hyperthyroidism before and after treatment.
No major thermogenic role for (Na+ + K+)-dependent adenosine triphosphatase apparent in hepatocytes from hyperthyroid rats.
Ouabain-binding sites of reticulocytes from guinea pigs treated with triiodothyronine.
Stimulation of the Na+,K(+)-ATPase activity of K562 human erythroleukemia cells by triiodothyronine.
The contribution of ATP turnover by the Na+/K+-ATPase to the rate of respiration of hepatocytes. Effects of thyroid status and fatty acids.
The effect of hyperthyroidism on in vivo aging of erythrocyte ouabain-binding sites and intracellular sodium and potassium.
[A histochemical study of gastric adenosine triphosphatase, alkaline and acid phosphatase in experimental hypo- and hyperthyroidism]
[Adenosine triphosphatase activity of the liver and micro- and macroelement levels in the organism of white rats in experimental hyperthyroidism]
[THE ADENOSINE TRIPHOSPHATASE ACTIVITY OF LEUKOCYTE HOMOGENATES IN HYPERTHYROIDISM.]
Hypoglycemia
The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease.
Hypokalemia
Distal renal tubular acidosis and the potassium enigma.
Effects of digitalis on cell biochemistry: sodium pump inhibition.
Effects of hypokalemia on the cardiotropic actions of digoxin in dogs. Correlation with inhibition of cardiac Na+,K+-adenosine triphosphatase.
Epinephrine-induced hypokalemia: the role of beta adrenoceptors.
Expression of Na(+)-K(+)-ATPase alpha- and beta-subunits along rat nephron: isoform specificity and response to hypokalemia.
Hypokalemia and anesthetic implications.
Significance of sodium pump isoforms in digitalis therapy.
The role of a humoral Na+,K+-ATPase inhibitor in regulating precapillary vessel tone.
Hypoparathyroidism
X-linked hypoparathyroidism region on Xq27 is evolutionarily conserved with regions on 3q26 and 13q34 and contains a novel P-type ATPase.
Hypotension
Modulation of Cardiovascular Function in Primary Hypertension in Rat by SKA-31, an Activator of KCa2.x and KCa3.1 Channels.
Hypothyroidism
Effect of thyroid status on the development of the different molecular forms of Na+,K+-ATPase in rat brain.
Ion flux and Na+,K+-ATPase activity of erythrocytes and leucocytes in thyroid disease.
Modulation of glutamate levels and Na+,K+-ATPase activity contributes to the chrysin memory recovery in hypothyroidism mice.
The Effects of Altered Membrane Cholesterol Levels on Sodium Pump Activity in Subclinical Hypothyroidism.
Infections
Adenosine triphosphatase activity associated with bovine erythrocyte membranes during infection with Anaplasma marginale.
Altered expression of sodium pump isoforms in the inflamed intestine of Trichinella spiralis-infected rats.
Changes in Na,K-ATPase, sodium ion, and glucose transport in isolated enterocytes in an experimental model of malabsorption.
Effects of Cryptocaryon irritans infection on the survival, feeding, respiratory rate and ionic regulation of the marbled rockfish Sebastiscus marmoratus.
Effects of glycyrrhizin on the growth cycle and ATPase activity of PRRSV-2-infected MARC-145 cells.
Hypotheses about sub-optimal hydration in the weeks before coronavirus disease (COVID-19) as a risk factor for dying from COVID-19.
Induction of a Na+/K+-ATPase-dependent form of autophagy triggers preferential cell death of human immunodeficiency virus type-1-infected macrophages.
Localization of H(+)-ATPases in soybean root nodules.
Multiplex PCR for the diagnosis of red sea bream iridoviruses isolated in Korea.
PDE1 encodes a P-type ATPase involved in appressorium-mediated plant infection by the rice blast fungus Magnaporthe grisea.
Schistosoma mansoni: fine structural localization of tegumental adenosine triphosphatases.
Screening of Natural Extracts for Inhibitors against Japanese Encephalitis Virus Infection.
Selective cell death of latently HIV-infected CD4+ T cells mediated by autosis inducing nanopeptides.
Stress effects of amyloodiniosis in gilthead sea bream Sparus aurata.
The antidiarrhoeal evaluation of Psidium guajava L. against enteropathogenic Escherichia coli induced infectious diarrhoea.
The Vacuolar Ca2+ ATPase Pump Pmc1p Is Required for Candida albicans Pathogenesis.
Thyroid status and adenosine triphosphatase activity in experimental Trypanosoma congolense infection in rabbits.
Influenza, Human
Glycolytic control of vacuolar-type ATPase activity: A mechanism to regulate influenza viral infection.
Na+/K+-ATPase as a Target of Cardiac Glycosides for the Treatment of SARS-CoV-2 Infection.
Pathogenesis of influenza-induced acute respiratory distress syndrome.
Insulin Resistance
Altered expression and insulin-induced trafficking of Na+, K+-ATPase in rat skeletal muscle: effects of high fat diet and exercise.
Association of sick sinus syndrome with hyperinsulinemia and insulin resistance in patients with non-insulin-dependent diabetes mellitus: report of four cases.
DR-region of Na+/K+-ATPase is a target to ameliorate hepatic insulin resistance in obese diabetic mice.
Expression and Cellular Distribution of Glucose Transporters and Alpha Subunits of Na+/K+-ATPase in the Heart of Fructose-fed Female Rats: The Role of Estradiol.
Insulin sensitivity of rat muscle sodium pump.
Role of muscle in regulating extracellular [K+].
Short-term K(+) deprivation provokes insulin resistance of cellular K(+) uptake revealed with the K(+) clamp.
The effect of oral glucose on the leucocyte sodium pump in normal and obese subjects.
Intellectual Disability
Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation.
Early Treatment in Acute Severe Encephalopathy Caused by ATP1A2 Mutation of Familial Hemiplegic Migraine Type 2: Case Report and Literature Review.
Functional correlation of ATP1A2 mutations with phenotypic spectrum: from pure hemiplegic migraine to its variant forms.
Severe episodic neurological deficits and permanent mental retardation in a child with a novel FHM2 ATP1A2 mutation.
Intermittent Claudication
Histochemical changes in striated muscle in patients with intermittent claudication.
Intestinal Volvulus
Ivermectin: concentration-dependent effects on adenosine triphosphatases in adult worms of Onchocerca volvulus.
Intraabdominal Infections
Increased hepatic microsomal adenosine triphosphatase activity secondary to intra-abdominal infection.
Intracranial Embolism
Microsphere embolism-induced changes in noradrenaline uptake of the cerebral cortex in rats.
Iron Deficiencies
Changes in the cochlear iron enzymes and adenosine triphosphatase in experimental iron deficiency.
Ischemic Stroke
Magnesium lithospermate B possesses inhibitory activity on Na+,K+-ATPase and neuroprotective effects against ischemic stroke.
Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study.
Kidney Diseases
Maximum binding of ouabain to erythrocytes in relation to a family history of essential hypertension, sodium balance and body weight in normotensive children.
Kidney Failure, Chronic
Abnormal cation transport in uremia. Mechanisms in adipocytes and skeletal muscle from uremic rats.
Biochemical abnormalities of platelets in renal failure. Evidence for decreased platelet serotonin, adenosine diphosphate and Mg-dependent adenosine triphosphatase.
Effects of acute and chronic uremia on active cation transport in rat myocardium.
Endogenous cardiac glycosidelike compounds.
Garlic (Allium sativum) exhibits a cardioprotective effect in experimental chronic renal failure rat model by reducing oxidative stress and controlling cardiac Na+/K+-ATPase activity and Ca2+ levels.
Inhibition of Na+,K+-stimulated ATPase in the cochlea of the guinea pig. A potential cause of disturbed inner ear function in terminal renal failure.
Marinobufagenin impairs first trimester cytotrophoblast differentiation.
Potassium in skeletal muscle in untreated primary hypertension and in chronic renal failure, studied by X-ray fluorescence technique.
Red blood cell calcium level in chronic renal failure: effect of continuous ambulatory peritoneal dialysis.
Reversal of sodium pump inhibitor induced vascular smooth muscle contraction with digibind. Stoichiometry and its implications.
Specificity of the volume-sensitive sodium pump inhibitor isolated from human peritoneal dialysate in chronic renal failure.
[Effect of hemodialysis on the erythrocyte sodium, potassium adenosine triphosphatase activity in children with chronic renal failure]
Kidney Neoplasms
Cardiotonic Steroids-Mediated Targeting of the Na(+)/K(+)-ATPase to Combat Chemoresistant Cancers.
Kwashiorkor
Erythrocyte membrane Na+ and K+ activated adenosine triphosphatase in protein-calorie malnutrition.
Lecithin Cholesterol Acyltransferase Deficiency
Study of erythrocytes in a hereditary hemolytic syndrome (HHS): comparison with erythrocytes in lecithin:cholesterol acyltransferase (LCAT) deficiency.
Leigh Disease
A novel mitochondrial ATPase 6 point mutation in familial bilateral striatal necrosis.
Mitochondrial disorders.
Mitochondrial DNA point mutation T9176C in Leigh syndrome.
Leiomyosarcoma
Copper ions are novel therapeutic agents for uterine leiomyosarcoma.
Lesch-Nyhan Syndrome
Effect of hypoxanthine on Na+,K+-ATPase activity and some parameters of oxidative stress in rat striatum.
Leukemia
Electron microscopic observations on the adenosine triphosphatase activity of a murine (Rauscher) and a canine leukemia virus.
Expression of multiple Na+,K+-adenosine triphosphatase isoform genes in human hematopoietic cells. Behavior of the novel A3 isoform during induced maturation of HL60 cells.
Leucocyte sodium-potassium adenosine triphosphatase and leukemia.
Membrane transport changes in an adriamycin-resistant murine leukemia cell line and in its sensitive parental cell line.
[Demonstration of adenosine triphosphatase in blood smears of acute leukemias and comparison with other enzyme-cytochemical reactions]
[Stereological characteristics and enzymatic activity of myocardial capillaries in different variants of pathology and death (data from immediate autopsies)]
Leukemia, Erythroblastic, Acute
Characterization of a Ca2+-stimulated Mg2+-dependent adenosine triphosphatase in Friend murine erythroleukemia cell plasma membranes.
The program of Friend cell erythroid differentiation: early changes in Na+/K+ ATPase function.
Leukemia, Lymphoid
[Effects of ouabain at low concentrations on growth of leukemia cells]
Leukemia, Megakaryoblastic, Acute
[Effects of ouabain at low concentrations on growth of leukemia cells]
Leukemia, Myeloid, Acute
Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor.
Lichen Planus, Oral
Assessment of langerhans cells in oral lichen planus by ATPase histochemistry: a clinicopathologic correlation.
Liver Diseases
Assessment of Adenosine Triphosphatase Phospholipid Transporting 8B1 (ATP8B1) Function in Patients With Cholestasis With ATP8B1 Deficiency by Using Peripheral Blood Monocyte-Derived Macrophages.
Evidence that adenosine triphosphatase is one of the mitochondrial antigens of autoimmune liver disease [proceedings]
FIC1, a P-type ATPase linked to cholestatic liver disease, has homologues (ATP8B2 and ATP8B3) expressed throughout the body.
Inhibition of rat brain Na+,K+-ATPase activity by serum from patients with fulminant hepatic failure.
[Adenosine triphosphatase activity of erythrocytes in liver diseases in children]
[Comparative characteristics of adenosine triphosphatase activity in the erythrocytes of patients with acute and chronic liver diseases, chronic cholecystitis and in HBs antigen carriers]
Liver Failure, Acute
A study in vitro of the sodium pump in fulminant hepatic failure.
Inhibition of rat brain Na+,K+-ATPase activity by serum from patients with fulminant hepatic failure.
Liver Neoplasms
Oxidative Stress and Apoptotic Responses Elicited by Nostoc-Synthesized Silver Nanoparticles against Different Cancer Cell Lines.
Liver Neoplasms, Experimental
Membranous effects on adenosine triphosphatase activities of mitochondria from rat liver and Morris hepatoma 3924A.
Lung Injury
Electroporation-mediated in vivo gene delivery of the Na+/K+-ATPase pump reduced lung injury in a mouse model of lung contusion.
Improving survival by increasing lung edema clearance: is airspace delivery of dopamine a solution?
Omega-9 Oleic Acid Induces Fatty Acid Oxidation and Decreases Organ Dysfunction and Mortality in Experimental Sepsis.
Lung Neoplasms
Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways.
Clinical outcome of cisplatin-based chemotherapy is associated with the polymorphisms of GSTP1 and XRCC1 in advanced non-small cell lung cancer patients.
Copper-transporting P-type adenosine triphosphatase (ATP7A) is associated with platinum-resistance in non-small cell lung cancer (NSCLC).
Cytotoxic and non-cytotoxic cardiac glycosides isolated from the combined flowers, leaves, and twigs of Streblus asper.
Cytotoxicity of glucoevatromonoside alone and in combination with chemotherapy drugs and their effects on Na+,K+-ATPase and ion channels on lung cancer cells.
Evaluation of the relationship of erythrocyte membrane Na+/K+-ATPase enzyme activity and tumor response to chemoradiotherapy in patients diagnosed with locally advanced nonsmall cell lung cancer and glioblastoma multiforme.
Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) correlates with cisplatin resistance in human non-small cell lung cancer xenografts.
MiR-495 enhances the sensitivity of non-small cell lung cancer cells to platinum by modulation of copper-transporting P-type adenosine triphosphatase A (ATP7A).
New 99mTc-Labeled Digitoxigenin Derivative for Cancer Cell Identification.
Role of sodium pump systems to determine sensitivity to mitomycin C in non-small cell lung cancer cell lines.
The alpha1 subunit of the sodium pump could represent a novel target to combat non-small cell lung cancers.
Lymphoma
Malignant lymphomas in the acquired immunodeficiency syndrome. Additional evidence for a B-cell origin.
Mg2+-dependent adenosine triphosphatase as an enzyme histochemical marker for the lymphomas of B-cell origin.
Lymphoma, B-Cell
Activation of novel estrogen receptor GPER results in inhibition of cardiocyte apoptosis and cardioprotection.
Oxidative Stress and Apoptotic Responses Elicited by Nostoc-Synthesized Silver Nanoparticles against Different Cancer Cell Lines.
Lymphoma, Non-Hodgkin
An enzyme histochemical study of non-Hodgkin's lymphoma and allied disease.
[Circadian rhythm of adenosine triphosphatase activity and 32P content in Pliss lymphosarcoma]
Malaria
PbGCbeta is essential for Plasmodium ookinete motility to invade midgut cell and for successful completion of parasite life cycle in mosquitoes.
Malnutrition
Death during recovery from severe malnutrition and its possible relationship to sodium pump activity in the leucocyte.
Na+,K+-ATPase in developing rat brain during undernutrition.
Oedema in protein energy malnutrition: the role of the sodium pump.
Reduction in vitro of red cell glutathione reproduces defects of cellular sodium transport seen in oedematous malnutrition.
[Subcellular distribution of the activity of the adenosine triphosphatase system during postnatal maturation of rat brain: influence of malnutrition]
Mania
Cognitive flexibility impairment and reduced frontal cortex BDNF expression in the ouabain model of mania.
Effect of ouabain on sodium pump alpha-isoform expression in an animal model of mania.
Efficacy of olanzapine and haloperidol in an animal model of mania.
Endogenous digoxin-like immunoreactive factor (DLIF) serum concentrations are decreased in manic bipolar patients compared to normal controls.
Evaluation of neuroprotection by lithium and valproic acid against ouabain-induced cell damage.
Intracerebroventricular administration of ouabain as a model of mania in rats.
Lithium prevents ouabain-induced behavioral changes. Toward an animal model for manic depression.
Mimicking human bipolar ion dysregulation models mania in rats.
Na+,K+-ATPase activity in an animal model of mania.
Massive Hepatic Necrosis
Preventive effect of zinc compounds, polaprezinc and zinc acetate against the onset of hepatitis in Long-Evans Cinnamon rat.
Mastitis
Polymorphisms of the ATP1A1 gene associated with mastitis in dairy cattle.
Mastocytoma
Effect of D-glucosamine on growth and several functions of cultured mastocytoma P-815 cells.
Medulloblastoma
Immunohistochemical analyses of alpha1 and alpha3 Na+/K+-ATPase subunit expression in medulloblastomas.
Melanoma
Activity of BK(Ca) channel is modulated by membrane cholesterol content and association with Na+/K+-ATPase in human melanoma IGR39 cells.
Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways.
Cardiotonic Steroids-Mediated Targeting of the Na(+)/K(+)-ATPase to Combat Chemoresistant Cancers.
Identification and cloning of genes displaying elevated expression as a consequence of metastatic progression in human melanoma cells by rapid subtraction hybridization.
The Sodium Pump alpha1 Subunit: a Disease Progression-Related Target for Metastatic Melanoma Treatment.
Memory Disorders
Modulation of glutamate levels and Na+,K+-ATPase activity contributes to the chrysin memory recovery in hypothyroidism mice.
Multitarget Effect of 2-(4-(Methylthio)phenyl)-3-(3-(piperidin-1-yl)propyl)thiazolidin-4-one in a Scopolamine-Induced Amnesic Rat Model.
The neuroprotective role of melatonin in a gestational hypermethioninemia model.
Meniere Disease
Possible functional roles of Na+,K+-ATPase in the inner ear and their relevance to Ménière's disease.
Meningitis
Increased Na+,K+-ATPase activity in the rat brain after meningitis induction by Streptococcus pneumoniae.
Menkes Kinky Hair Syndrome
13 novel putative mutations in ATP7A found in a cohort of 25 Italian families.
Adipocyte-specific disruption of ATPase copper transporting ? in mice accelerates lipoatrophy.
ATP7A (Menkes protein) functions in axonal targeting and synaptogenesis.
ATP7A gene addition to the choroid plexus results in long-term rescue of the lethal copper transport defect in a Menkes disease mouse model.
ATP7A transgenic and nontransgenic mice are resistant to high copper exposure.
Characterization of the exon structure of the Menkes disease gene using vectorette PCR.
Copper homeostasis in the CNS: a novel link between the NMDA receptor and copper homeostasis in the hippocampus.
Direct interactions of adaptor protein complexes 1 and 2 with the copper transporter ATP7A mediate its anterograde and retrograde trafficking.
Functional expression of the menkes disease protein reveals common biochemical mechanisms among the copper-transporting P-type ATPases.
Genomic organization of ATOX1, a human copper chaperone.
L-Threo-Dihydroxyphenylserine corrects neurochemical abnormalities in a menkes disease mouse model.
Menkes disease diagnosed by a novel ATP7A frameshift mutation in a patient with infantile spasms-a case report.
Molecular basis of the brindled mouse mutant (Mo(br)): a murine model of Menkes disease.
Mutational analysis of ATP7B and genotype-phenotype correlation in Japanese with Wilson's disease.
Safety of intracerebroventricular copper histidine in adult rats.
Sequence, mapping and disruption of CCC2, a gene that cross-complements the Ca(2+)-sensitive phenotype of csg1 mutants and encodes a P-type ATPase belonging to the Cu(2+)-ATPase subfamily.
Wilson disease and Menkes disease: new handles on heavy-metal transport.
Wilson's disease: a new gene and an animal model for an old disease.
[Copper metabolism and genetic disorders].
Mesothelioma
Immunohistochemical and histochemical markers of primary lung cancer, lung metastases, and pleural mesotheliomas.
Metabolic Syndrome
Decreased Na+/K+-ATPase Activity and Altered Susceptibility to Peroxidation and Lipid Composition in the Erythrocytes of Metabolic Syndrome Patients with Coronary Artery Disease.
Regulation of the Na,K-ATPase: Special implications for cardiovascular complications of metabolic syndrome.
Transactivation of epidermal growth factor receptor in vascular and renal systems in rats with experimental hyperleptinemia: role in leptin-induced hypertension.
Microcephaly
ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.
Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations.
Migraine Disorders
A case of familial hemiplegic migraine associated with a novel ATP1A2 gene mutation.
A Chinese family with familial hemiplegic migraine type 2 due to a novel missense mutation in ATP1A2.
A genome-wide linkage scan provides evidence for both new and previously reported loci influencing common migraine.
A missense variant of the ATP1A2 gene is associated with a novel phenotype of progressive sensorineural hearing loss associated with migraine.
A novel ATP1A2 gene mutation in an Irish familial hemiplegic migraine kindred.
A novel ATP1A2 gene mutation in familial hemiplegic migraine and epilepsy.
A Novel ATP1A2 Gene Variant Associated With Pure Sporadic Hemiplegic Migraine Improved After Patent Foramen Ovale Closure: A Case Report.
A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients.
A novel de novo nonsense mutation in ATP1A2 associated with sporadic hemiplegic migraine and epileptic seizures.
A novel lethal recognizable polymicrogyric syndrome caused by ATP1A2 homozygous truncating variants.
A novel missense ATP1A2 mutation in a Finnish family with familial hemiplegic migraine type 2.
A Wide Clinical Phenotype Spectrum in Patients With ATP1A2 Mutations.
Acute encephalopathy in familial hemiplegic migraine with ATP1A2 mutation.
Advances in genetics of migraine.
Alternating hemiplegia of childhood and a pathogenic variant of ATP1A3: a case report and pathophysiological considerations.
Alternating hemiplegia of childhood: no mutations in the second familial hemiplegic migraine gene ATP1A2.
Amino acid changes in the amino terminus of the Na,K-adenosine triphosphatase alpha-2 subunit associated to familial and sporadic hemiplegic migraine.
An Infant With Epilepsy and Recurrent Hemiplegia due to Compound Heterozygous Variants in ATP1A2.
Analysis of amplicon-based NGS data from neurological disease gene panels: a new method for allele drop-out management.
Analysis of chromosome 1 microsatellite markers and the FHM2-ATP1A2 gene mutations in migraine pedigrees.
Astrocytes in Atp1a2-deficient heterozygous mice exhibit hyperactivity after induction of cortical spreading depression.
ATP1A2 gene mutations are not present in two sisters with basilar-type migraine associated with menses.
ATP1A2 mutations in 11 families with familial hemiplegic migraine.
ATP1A2 Mutations in Migraine: Seeing through the Facets of an Ion Pump onto the Neurobiology of Disease.
ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.
Basilar-type migraine: clinical, epidemiologic, and genetic features.
Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations.
Biphasic neurovascular changes in prolonged migraine aura in familial hemiplegic migraine type 2.
CACNA1A-Linked Hemiplegic Migraine in GLUT 1 Deficiency Syndrome: A Case Report.
CACNA1A-p.Thr501Met mutation associated with familial hemiplegic migraine: a family report.
Characteristics of cortical spreading depression and c-Fos expression in transgenic mice having a mutation associated with familial hemiplegic migraine 2.
Clinical spectrum in three families with familial hemiplegic migraine type 2 including a novel mutation in the ATP1A2 gene.
Coexistence of CACNA1A, ATP1A2, and KCNN3 gene mutation in migraine patients with human platelet polymorphism.
De novo exonic duplication of ATP1A2 in Italian patient with hemiplegic migraine: a case report.
De novo mutations in ATP1A2 and CACNA1A are frequent in early-onset sporadic hemiplegic migraine.
Differential effect of FHM2 mutation on synaptic plasticity in distinct hippocampal regions.
Diverse functional consequences of mutations in the Na+/K+-ATPase alpha2-subunit causing familial hemiplegic migraine type 2.
Early onset severe ATP1A2 epileptic encephalopathy: Clinical characteristics and underlying mutations.
Early Treatment in Acute Severe Encephalopathy Caused by ATP1A2 Mutation of Familial Hemiplegic Migraine Type 2: Case Report and Literature Review.
Elicited repetitive daily blindness: a new phenotype associated with hemiplegic migraine and SCN1A mutations.
Enhanced susceptibility to cortical spreading depression in two types of Na
Epilepsy as part of the phenotype associated with ATP1A2 mutations.
Epilepsy in hemiplegic migraine: Genetic mutations and clinical implications.
Erratum to: De novo exonic duplication of ATP1A2 in Italian patient with hemiplegic migraine: a case report.
Exploring Neuronal Vulnerability to Head Trauma Using a Whole Exome Approach.
Exploring the Hereditary Nature of Migraine.
Familial hemiplegic migraine is associated with febrile seizures in an FHM2 family with a novel de novo ATP1A2 mutation.
Familial hemiplegic migraine mutations affect Na,K-ATPase domain interactions.
Familial hemiplegic migraine presenting as recurrent encephalopathy in a Native Indian family.
Familial hemiplegic migraine type 2 due to a novel missense mutation in ATP1A2.
Familial Hemiplegic Migraine Type 3 (FHM3) With an SCN1A Mutation in a Chinese Family: A Case Report.
Familial Hemiplegic Migraine with an ATP1A4 Mutation: Clinical Spectrum and Carbamazepine Efficacy.
Familial Hemiplegic Migraine With Asymmetric Encephalopathy Secondary to ATP1A2 Mutation: A Case Series.
Familial Hemiplegic Migraine with Severe Attacks: A New Report with ATP1A2 Mutation.
Familial hemiplegic migraine.
First case of compound heterozygosity in Na,K-ATPase gene ATP1A2 in familial hemiplegic migraine.
Functional analysis of human Na(+)/K(+)-ATPase familial or sporadic hemiplegic migraine mutations expressed in Xenopus oocytes.
Functional characterization of a novel C-terminal ATP1A2 mutation causing hemiplegic migraine and epilepsy.
Functional correlation of ATP1A2 mutations with phenotypic spectrum: from pure hemiplegic migraine to its variant forms.
Functional effects of Na+,K+-ATPase gene mutations.
Genetic effects of ATP1A2 in familial hemiplegic migraine type II and animal models.
Genetic studies of Polish migraine patients: screening for causative mutations in four migraine-associated genes.
Genetics of migraine: an update with special attention to genetic comorbidity.
Genetics of the epilepsies.
Genome-wide screen for modifiers of Na + /K + ATPase alleles identifies critical genetic loci.
Genomewide significant linkage to migrainous headache on chromosome 5q21.
Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump alpha2 subunit associated with familial hemiplegic migraine type 2.
Haplotype-based systematic association studies of ATP1A2 in migraine with aura.
Hemiplegic migraine type 2 caused by a novel variant within the P-type ATPase motif in ATP1A2 concomitant with a CACNA1A variant.
Hemiplegic migraine with reversible cerebral vasoconstriction caused by ATP1A2 mutations.
Identification of novel genes involved in migraine.
Impaired plasma membrane targeting or protein stability by certain ATP1A2 mutations identified in sporadic or familial hemiplegic migraine.
Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2.
Inhibition of phosphorylation of na+,k+-ATPase by mutations causing familial hemiplegic migraine.
Insights into the Pathology of the ?2-Na(+)/K(+)-ATPase in Neurological Disorders; Lessons from Animal Models.
Intravenous Nimodipine Treatment for Severe Episode of ATP1A2 Hemiplegic Migraine.
Kinetic alterations due to a missense mutation in the Na,K-ATPase alpha2 subunit cause familial hemiplegic migraine type 2.
Linkage analysis and disease models in benign familial infantile seizures: a study of 16 families.
Migraine and epilepsy: A focus on overlapping clinical, pathophysiological, molecular, and therapeutic aspects.
Migraine in the era of precision medicine.
Migraine: Genetic Variants and Clinical Phenotypes.
Migraine: Role of the TRESK two-pore potassium channel.
Migrainous vertigo: mutation analysis of the candidate genes CACNA1A, ATP1A2, SCN1A, and CACNB4.
Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures.
Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine.
Na+/K+-ATPase ? isoform deficiency results in distinct spreading depolarization phenotypes.
Neurovascular changes in prolonged migraine aura in FHM with a novel ATP1A2 gene mutation.
New CACNA1A deletions are associated to migraine phenotypes.
New discoveries about the second gene for familial hemiplegic migraine, ATP1A2.
No mutations in CACNA1A and ATP1A2 in probands with common types of migraine.
Novel missense mutation in the ATP1A2 gene associated with atypical sporapedic hemiplegic migraine.
Novel mutations in the Na+, K+-ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions.
Opening of the blood-brain barrier preceding cortical edema in a severe attack of FHM type II.
Partially Reversible Cortical Metabolic Dysfunction in Familial Hemiplegic Migraine With Prolonged Aura.
Physical mapping and characterization of the human Na,K-ATPase isoform, ATP1A4.
Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study.
Prolonged Hyperperfusion in a Child With ATP1A2 Defect-Related Hemiplegic Migraine.
Prolonged sporadic hemiplegic migraine associated with a novel de novo missense ATP1A2 gene mutation.
Pulmonary arterial hypertension in familial hemiplegic migraine with ATP1A2 channelopathy.
Rare missense variants in ATP1A2 in families with clustering of common forms of migraine.
Recent findings in headache genetics.
Recurrent ATP1A2 mutations in Portuguese families with familial hemiplegic migraine.
Recurrent coma and fever in familial hemiplegic migraine type 2. A prospective 15-year follow-up of a large family with a novel ATP1A2 mutation.
Screen for CACNA1A and ATP1A2 mutations in sporadic hemiplegic migraine patients.
Screening of CACNA1A and ATP1A2 genes in hemiplegic migraine: clinical, genetic, and functional studies.
Serial magnetic resonance imaging findings during severe attacks of familial hemiplegic migraine type 2: a case report.
Severe attacks of familial hemiplegic migraine, childhood epilepsy and ATP1A2 mutation.
Shared mechanisms of epilepsy, migraine and affective disorders.
Significant linkage to migraine with aura on chromosome 11q24.
Single-fiber EMG in familial hemiplegic migraine.
Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks.
Sporadic Hemiplegic Migraine with ATP1A2 and Prothrombin Gene Mutations.
The CACNA1A and ATP1A2 genes are not involved in dominantly inherited migraine with aura.
The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine: A clinical and genetic study in Finnish migraine families.
The genetic relationship between epilepsy and hemiplegic migraine.
The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence.
The kinetics of non-synaptically triggered acute excitotoxic responses in the central nervous system observed using intrinsic optical signals.
The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations.
Toward a molecular genetic classification of familial hemiplegic migraine.
Two de novo mutations in the Na,K-ATPase gene ATP1A2 associated with pure familial hemiplegic migraine.
Two novel functional mutations in the Na+,K+-ATPase alpha2-subunit ATP1A2 gene in patients with familial hemiplegic migraine and associated neurological phenotypes.
Update on the genetics of migraine.
Variability of familial hemiplegic migraine with novel A1A2 Na+/K+-ATPase variants.
Variable manifestations of familial hemiplegic migraine associated with reversible cerebral edema in children.
[ATP1A2 : a key player in familial hemiplegic migraine.]
[Genetics of migraines: from ionic channels to single nucleotide polymorphisms?]
[Genetics of migraine]
[The Na+,K+ pump continues to cause surprise]
Migraine with Aura
A case of familial hemiplegic migraine associated with a novel ATP1A2 gene mutation.
A Chinese family with familial hemiplegic migraine type 2 due to a novel missense mutation in ATP1A2.
A genome-wide linkage scan provides evidence for both new and previously reported loci influencing common migraine.
A novel ATP1A2 gene mutation in an Irish familial hemiplegic migraine kindred.
A novel ATP1A2 gene mutation in familial hemiplegic migraine and epilepsy.
A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients.
A novel lethal recognizable polymicrogyric syndrome caused by ATP1A2 homozygous truncating variants.
A novel missense ATP1A2 mutation in a Finnish family with familial hemiplegic migraine type 2.
A Wide Clinical Phenotype Spectrum in Patients With ATP1A2 Mutations.
Acute encephalopathy in familial hemiplegic migraine with ATP1A2 mutation.
Alternating hemiplegia of childhood and a pathogenic variant of ATP1A3: a case report and pathophysiological considerations.
Alternating hemiplegia of childhood: no mutations in the second familial hemiplegic migraine gene ATP1A2.
An Infant With Epilepsy and Recurrent Hemiplegia due to Compound Heterozygous Variants in ATP1A2.
Analysis of amplicon-based NGS data from neurological disease gene panels: a new method for allele drop-out management.
Analysis of chromosome 1 microsatellite markers and the FHM2-ATP1A2 gene mutations in migraine pedigrees.
Astrocytes in Atp1a2-deficient heterozygous mice exhibit hyperactivity after induction of cortical spreading depression.
ATP1A2 gene mutations are not present in two sisters with basilar-type migraine associated with menses.
ATP1A2 mutations in 11 families with familial hemiplegic migraine.
ATP1A2 Mutations in Migraine: Seeing through the Facets of an Ion Pump onto the Neurobiology of Disease.
ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.
Basilar-type migraine: clinical, epidemiologic, and genetic features.
Biallelic loss of function variants in ATP1A2 cause hydrops fetalis, microcephaly, arthrogryposis and extensive cortical malformations.
Biphasic neurovascular changes in prolonged migraine aura in familial hemiplegic migraine type 2.
CACNA1A-p.Thr501Met mutation associated with familial hemiplegic migraine: a family report.
Characteristics of cortical spreading depression and c-Fos expression in transgenic mice having a mutation associated with familial hemiplegic migraine 2.
Clinical spectrum in three families with familial hemiplegic migraine type 2 including a novel mutation in the ATP1A2 gene.
Differential effect of FHM2 mutation on synaptic plasticity in distinct hippocampal regions.
Diverse functional consequences of mutations in the Na+/K+-ATPase alpha2-subunit causing familial hemiplegic migraine type 2.
Early Treatment in Acute Severe Encephalopathy Caused by ATP1A2 Mutation of Familial Hemiplegic Migraine Type 2: Case Report and Literature Review.
Elicited repetitive daily blindness: a new phenotype associated with hemiplegic migraine and SCN1A mutations.
Enhanced susceptibility to cortical spreading depression in two types of Na
Epilepsy as part of the phenotype associated with ATP1A2 mutations.
Exploring the Hereditary Nature of Migraine.
Familial basilar migraine associated with a new mutation in the ATP1A2 gene.
Familial hemiplegic migraine is associated with febrile seizures in an FHM2 family with a novel de novo ATP1A2 mutation.
Familial hemiplegic migraine presenting as recurrent encephalopathy in a Native Indian family.
Familial hemiplegic migraine type 2 due to a novel missense mutation in ATP1A2.
Familial Hemiplegic Migraine Type 3 (FHM3) With an SCN1A Mutation in a Chinese Family: A Case Report.
Familial Hemiplegic Migraine with an ATP1A4 Mutation: Clinical Spectrum and Carbamazepine Efficacy.
Familial Hemiplegic Migraine With Asymmetric Encephalopathy Secondary to ATP1A2 Mutation: A Case Series.
Familial Hemiplegic Migraine with Severe Attacks: A New Report with ATP1A2 Mutation.
First case of compound heterozygosity in Na,K-ATPase gene ATP1A2 in familial hemiplegic migraine.
Functional characterization of a novel C-terminal ATP1A2 mutation causing hemiplegic migraine and epilepsy.
Functional correlation of ATP1A2 mutations with phenotypic spectrum: from pure hemiplegic migraine to its variant forms.
Functional effects of Na+,K+-ATPase gene mutations.
Genetic effects of ATP1A2 in familial hemiplegic migraine type II and animal models.
Genetic studies of Polish migraine patients: screening for causative mutations in four migraine-associated genes.
Genetics of migraine: an update with special attention to genetic comorbidity.
Genetics of the epilepsies.
Genome-wide screen for modifiers of Na + /K + ATPase alleles identifies critical genetic loci.
Genomewide significant linkage to migrainous headache on chromosome 5q21.
Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump alpha2 subunit associated with familial hemiplegic migraine type 2.
Haplotype-based systematic association studies of ATP1A2 in migraine with aura.
Identification of novel genes involved in migraine.
Impaired plasma membrane targeting or protein stability by certain ATP1A2 mutations identified in sporadic or familial hemiplegic migraine.
Increased susceptibility to cortical spreading depression and epileptiform activity in a mouse model for FHM2.
Inhibition of phosphorylation of na+,k+-ATPase by mutations causing familial hemiplegic migraine.
Insights into the Pathology of the ?2-Na(+)/K(+)-ATPase in Neurological Disorders; Lessons from Animal Models.
Kinetic alterations due to a missense mutation in the Na,K-ATPase alpha2 subunit cause familial hemiplegic migraine type 2.
Linkage analysis and disease models in benign familial infantile seizures: a study of 16 families.
Migraine in the era of precision medicine.
Migraine: Role of the TRESK two-pore potassium channel.
Migrainous vertigo: mutation analysis of the candidate genes CACNA1A, ATP1A2, SCN1A, and CACNB4.
Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine.
Na+/K+-ATPase ? isoform deficiency results in distinct spreading depolarization phenotypes.
New CACNA1A deletions are associated to migraine phenotypes.
New discoveries about the second gene for familial hemiplegic migraine, ATP1A2.
Novel mutations in the Na+, K+-ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions.
Partially Reversible Cortical Metabolic Dysfunction in Familial Hemiplegic Migraine With Prolonged Aura.
Physical mapping and characterization of the human Na,K-ATPase isoform, ATP1A4.
Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study.
Pulmonary arterial hypertension in familial hemiplegic migraine with ATP1A2 channelopathy.
Rare missense variants in ATP1A2 in families with clustering of common forms of migraine.
Recent findings in headache genetics.
Recurrent ATP1A2 mutations in Portuguese families with familial hemiplegic migraine.
Recurrent coma and fever in familial hemiplegic migraine type 2. A prospective 15-year follow-up of a large family with a novel ATP1A2 mutation.
Severe attacks of familial hemiplegic migraine, childhood epilepsy and ATP1A2 mutation.
Shared mechanisms of epilepsy, migraine and affective disorders.
Significant linkage to migraine with aura on chromosome 11q24.
Single-fiber EMG in familial hemiplegic migraine.
The CACNA1A and ATP1A2 genes are not involved in dominantly inherited migraine with aura.
The contribution of CACNA1A, ATP1A2 and SCN1A mutations in hemiplegic migraine: A clinical and genetic study in Finnish migraine families.
The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence.
The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations.
Toward a molecular genetic classification of familial hemiplegic migraine.
Two de novo mutations in the Na,K-ATPase gene ATP1A2 associated with pure familial hemiplegic migraine.
Two novel functional mutations in the Na+,K+-ATPase alpha2-subunit ATP1A2 gene in patients with familial hemiplegic migraine and associated neurological phenotypes.
Update on the genetics of migraine.
Variability of familial hemiplegic migraine with novel A1A2 Na+/K+-ATPase variants.
Variable manifestations of familial hemiplegic migraine associated with reversible cerebral edema in children.
[ATP1A2 : a key player in familial hemiplegic migraine.]
[Genetics of migraines: from ionic channels to single nucleotide polymorphisms?]
[Genetics of migraine]
[The Na+,K+ pump continues to cause surprise]
Migraine without Aura
Analysis of chromosome 1 microsatellite markers and the FHM2-ATP1A2 gene mutations in migraine pedigrees.
Familial hemiplegic migraine mutations affect Na,K-ATPase domain interactions.
Mitochondrial Diseases
A De Novo Mutation in the Adenosine Triphosphatase (ATPase) 8 Gene in a Patient With Mitochondrial Disorder.
Monoclonal Gammopathy of Undetermined Significance
[The significance of the cytochemical adenosine triphosphatase reaction for the diagnosis of benign monoclonal gammopathy (author's transl)]
Mononeuropathies
Endoneurial ATPase activity in Tangier disease and other peripheral neuropathies.
Mouth Neoplasms
Modulatory Action of ?-Tocopherol on Erythrocyte Membrane Adenosine Triphosphatase against Radiation Damage in Oral Cancer.
Movement Disorders
A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients.
Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump.
Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia.
Multiple Sclerosis
A novel mitochondrial DNA deletion producing progressive external ophthalmoplegia associated with multiple sclerosis.
Na+- and K+-dependent adenosine triphosphatase and multiple sclerosis.
Na+- and K+-dependent adenosine triphosphatase changes in multiple sclerosis plaques.
Muscle Hypotonia
Ocular Hypotonia and Transient Decrease of Vision as a Consequence of Exposure to a Common Toad Poison.
Muscle Spasticity
Diamphenethide--a reassessment of its pharmacological action.
Mitochondria and degenerative disorders.
Muscular Atrophy
Aerobic Exercise Recovers Disuse-induced Atrophy Through the Stimulus of the LRP130/PGC-1? Complex in Aged Rats.
[Effects of Ligustrazine and Radix Astragali on activities of myosin adenosine triphosphatase of soleus muscle and muscle atrophy in tail-suspended rats]
[The preventive effects of one herbal compound on activities of myosin adenosine triphosphatase of muscle fibers and muscle atrophy in tail-suspended rat].
Muscular Diseases
A novel mitochondrial DNA deletion producing progressive external ophthalmoplegia associated with multiple sclerosis.
Adenosine triphosphatase and myopathy.
Crooked calf disease: a histological and histochemical examination of eight affected calves.
Gene-related protein surplus myopathies.
Muscular Dystrophies
Ouabain and erythrocyte-ghost adenosine triphosphatase. Effects in human muscular dystrophies.
Sodium channel and sodium pump in normal and pathological muscles from patients with myotonic muscular dystrophy and lower motor neuron impairment.
[Adenosine triphosphatase activities of the erythrocyte membrane in Duchenne's myodystrophy]
[Sodium- and potassium-dependent adenosine triphosphatase of erythrocyte shadows in patients with Duchenne's myodystrophy]
Muscular Dystrophy, Duchenne
Effect of ouabain upon erythrocyte membrane adenosine triphosphatase in Duchenne muscular dystrophy.
Erythrocyte cation-activated adenosine triphosphatases in Duchenne muscular dystrophy.
Erythrocyte membrane (Ca/+ + Mg/+)-activated adenosine triphosphatase in Duchenne muscular dystrophy.
Erythrocyte-ghost Ca2+-stimulated Mg2+-dependent adenosine triphosphatase in Duchenne muscular dystrophy.
Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders--Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy.
Superprecipitation and adenosine triphosphatase activity of myosin B in Duchenne muscular dystrophy.
The effect of ouabain on erythrocyte adenosine triphosphatase activity in relation to cell age in vivo and Duchenne muscular dystrophy.
The sodium pump of erythrocytes from patients with Duchenne muscular dystrophy: effect of ouabain on the active sodium flux and on (Na+, K+)ATPase.
Myalgia
Investigation of the relationships between different enzymes and postmortem duck muscle tenderization.
Myocardial Infarction
Characterization of a urinary bufodienolide Na+,K+-ATPase inhibitor in patients after acute myocardial infarction.
Immunofluorescent microscopy for the identification of human necrotic myocardium.
Noninvasive quantification of total sodium concentrations in acute reperfused myocardial infarction using 23Na MRI.
Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study.
Pretreatment with morin, a flavonoid, ameliorates adenosine triphosphatases and glycoproteins in isoproterenol-induced myocardial infarction in rats.
Preventive effect of naringin on isoproterenol-induced cardiotoxicity in Wistar rats: an in vivo and in vitro study.
Preventive effect of S-allylcysteine on membrane-bound enzymes and glycoproteins in normal and isoproterenol-induced cardiac toxicity in male Wistar rats.
Protective effect of Lagenaria siceraria (Mol) against membrane-bound enzyme alterations in isoproterenol-induced cardiac damage in rats.
The ?2-isoform of the Na+/K+-ATPase protects against pathological remodeling and ?-adrenergic desensitization after myocardial infarction.
Myocardial Ischemia
Alleviation of isoprenaline hydrochloride induced myocardial ischemia injury by brucine through the inhibition of Na+/K+-ATPase.
Benzodiazepine-based selective inhibitors of mitochondrial F1F0 ATP hydrolase.
Calpain-mediated impairment of Na+/K+-ATPase activity during early reperfusion contributes to cell death after myocardial ischemia.
Pharmacological profile of the selective mitochondrial F1F0 ATP hydrolase inhibitor BMS-199264 in myocardial ischemia.
[Study of the calmodulin-dependent regulation of calcium adenosine triphosphatase of erythrocyte membranes in patients with ischemic heart disease]
[The effect of laser irradiation of the blood on the adenosine triphosphatase activity of the erythrocyte membranes and on the cardiac activity indices in patients with ischemic heart disease]
Myocardial Reperfusion Injury
Antidigoxin antiserum prevents endogenous digitalis-like compound-mediated reperfusion injury via modulating sodium pump isoform gene expression.
Myocardial Stunning
Lack of the effect of superoxide dismutase and catalase on Na+,K+-ATPase activity in stunned rabbit hearts.
Myocarditis
[The catecholamine concentration and adenosine triphosphatase activity of the myocardium in experimental myocarditis]
Myopia
Disrupted potassium ion homeostasis in ciliary muscle in negative lens-induced myopia in Guinea pigs.
Myotonia
Diazacholesterol myotonia: accumulation of desmosterol and increased adenosine triphosphatase activity of sarcolemma.
Membrane desmosterol and the kinetics of the sarcolemmal Na+,K+-ATPase in myotonia induced by 20,25-diazacholesterol.
Myotonic Dystrophy
Localization of a human Na+,K+-ATPase alpha subunit gene to chromosome 19q12----q13.2 and linkage to the myotonic dystrophy locus.
Neoplasm Metastasis
Identification and cloning of genes displaying elevated expression as a consequence of metastatic progression in human melanoma cells by rapid subtraction hybridization.
Side population cells and drug resistance in breast cancer.
Neoplasms
(3H)ouabain binding to leukaemic cells and intralymphocytic sodium content in chronic lymphocytic leukaemia; no evidence for alterations of the Na+/K+-pump.
2.3 Å resolution cryo-EM structure of human p97 and mechanism of allosteric inhibition.
A comparative study of inner membrane enzymes and transport systems in mitochondria from R3230AC mammary tumor and normal rat mammary gland.
A cytochemical study on the salivary gland pleomorphic adenoma (mixed tumor) and the fetal and adult salivary gland.
A distinctive cutaneous malignant neoplasm expressing the Langerhans cell phenotype. Synchronous occurrence with B-chronic lymphocytic leukemia.
A Mg2+- and Ca2+-stimulated adenosine triphosphatase at the outer surface of Ehrlich ascites tumor cells.
A near-infrared light-controlled, ultrasensitive one-step photoelectrochemical detection of dual cell apoptosis indicators in living cancer cells.
A new water-soluble polythiophene derivative as a probe for real-time monitoring adenosine 5'-triphosphatase activity in lysosome of living cells.
Activation and proliferation signals in murine macrophages: stimulation of Na+,K+-ATPase activity by hemopoietic growth factors and other agents.
Activation of novel estrogen receptor GPER results in inhibition of cardiocyte apoptosis and cardioprotection.
Alteration by phenobarbital of membrane-associated enzymes including gamma glutamyl transpeptidase in mouse liver neoplasms.
An electron cytochemical demonstration and biochemical analysis of adenosine triphosphatase activity in cancer cell plasma membrane.
An evaluation of enzyme histochemistry in the diagnosis of childhood rhabdomyosarcoma.
Anti-inflammatory effects induced by pharmaceutical substances on inflammatory active brain astrocytes-promising treatment of neuroinflammation.
Anticancer ruthenium(III) complex KP1019 interferes with ATP-dependent Ca2+ translocation by sarco-endoplasmic reticulum Ca2+-ATPase (SERCA).
ARID1A immunohistochemistry improves outcome prediction in invasive urothelial carcinoma of urinary bladder.
Association of ATP7A expression and in vitro sensitivity to cisplatin in non-small cell lung cancer.
ATP6AP2 is Overexpressed in Breast Cancer and Promotes Breast Cancer Progression.
ATP7B expression is associated with in vitro sensitivity to cisplatin in non-small cell lung cancer.
ATPase inhibitory factor 1 is a potential prognostic marker for the migration and invasion of glioma.
Bilirubin attenuates bufadienolide-induced ventricular arrhythmias and cardiac dysfunction in Guinea-pigs by reducing elevated intracellular na(+) levels.
Bone marrow-infiltrating human neuroblastoma cells express high levels of calprotectin and HLA-G proteins.
BRIP1 inhibits the tumorigenic properties of cervical cancer by regulating RhoA GTPase activity.
Cancer mortality does not differ by antiarrhythmic drug use: A population-based cohort of Finnish men.
Cardenolide-induced lysosomal membrane permeabilization demonstrates therapeutic benefits in experimental human non-small cell lung cancers.
Cardiac glycoside bufalin blocks cancer cell growth by inhibition of Aurora A and Aurora B activation via PI3K-Akt pathway.
Cardiac Glycoside Ouabain Exerts Anticancer Activity via Downregulation of STAT3.
Cardiac glycosides block cancer growth through HIF-1?- and NF-?B-mediated Plk1.
Cardiotonic steroids on the road to anti-cancer therapy.
Cardiotonic Steroids-Mediated Na+/K+-ATPase Targeting Could Circumvent Various Chemoresistance Pathways.
Cardiotonic Steroids-Mediated Targeting of the Na(+)/K(+)-ATPase to Combat Chemoresistant Cancers.
Cinobufagin Triggers Defects in Spindle Formation and Cap-Dependent Translation in Liver Cancer Cells by Inhibiting the AURKA-mTOR-eIF4E Axis.
Correlation of ouabain-sensitive ion movements with cell-cycle activation.
Crosstalk between Na+,K+-ATPase and a volume-regulated anion channel in membrane microdomains of human cancer cells.
Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na+/K+-ATPase inhibition.
Different roles of proteolipids and 70-kDa subunits of V-ATPase in growth and death of cultured human cells.
Differential sensitivity of human gastric cancer ATPase and normal gastric mucosa ATPase to the synthetic mammalian lignan analogue 2,3-dibenzylbutane-1,4-diol (hattalin).
Digitalis, a targeted therapy for cancer?
Downregulation of RUVBL1 inhibits proliferation of lung adenocarcinoma cells by G1/S phase cell cycle arrest via multiple mechanisms.
Early uptake and continuous accumulation of thallium-201 chloride in a benign mixed tumor of soft tissue: Case Report.
Ecto-enzymes of mammary gland and its tumours. Ca2+- or Mg2+-stimulated adenosine triphosphatase and its perturbation by concanavalin A.
Editorial: on the road to multi-modal and pluri-disciplinary treatment of glioblastomas.
Effect of Ginkgo biloba extract 50 on immunity and antioxidant enzyme activities in ischemia reperfusion rats.
Engineering a prostate-specific membrane antigen-activated tumor endothelial cell prodrug for cancer therapy.
Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization.
Enzyme histochemical study on bone tumors.
Enzyme histochemistry and thyroid neoplasia.
Epithelioid sarcoma. Enzyme histochemical and ultrastructural study.
Evaluation of the relationship of erythrocyte membrane Na+/K+-ATPase enzyme activity and tumor response to chemoradiotherapy in patients diagnosed with locally advanced nonsmall cell lung cancer and glioblastoma multiforme.
Experimental evaluation of the usefulness of 201Tl-chloride scintigraphy for monitoring radiotherapeutic effects.
Expression of ATP7A in esophageal squamous cell carcinoma (ESCC) and its clinical significance.
Expression of the copper transporters hCtr1, ATP7A and ATP7B is associated with the response to chemotherapy and survival time in patients with resected non-small cell lung cancer.
Family of Na+,K+-ATPase genes. Intra-individual tissue-specific restriction fragment length polymorphism.
From Na+/K+-ATpase and Cardiac Glycosides to Cytotoxicity and Cancer Treatment.
Hellebrin and its aglycone form hellebrigenin display similar in vitro growth inhibitory effects in cancer cells and binding profiles to the alpha subunits of the Na+/K+-ATPase.
Hepatoprotective effect of Caesalpinia gilliesii and Cajanus cajan proteins against acetoaminophen overdose-induced hepatic damage.
Hepatoprotective potential of standardized Ficus species in intrahepatic cholestasis rat model: Involvement of nuclear factor-?B, and Farnesoid X receptor signaling pathways.
Histogenesis of Kaposi's sarcoma and angiosarcoma of the face and the scalp.
Histopathological and Immunohistochemical Characterization of Methyl Eugenol-induced Nonneoplastic and Neoplastic Neuroendocrine Cell Lesions in Glandular Stomach of Rats.
Hypotheses about sub-optimal hydration in the weeks before coronavirus disease (COVID-19) as a risk factor for dying from COVID-19.
Identification of a sodium pump Na+/K+ ATPase ?1-targeted peptide for PET imaging of breast cancer.
Immune and enzyme histochemical studies of a human hepatocellular carcinoma cell line producing hepatitis B surface antigen.
Impairment of sodium pump and Na+/H+ antiport in erythrocytes isolated from cancer patients.
Increase in adenosine triphosphatase activity of Ehrlich ascites tumor cells following serial cultivation in media with increased (hypertonic) NaCl content.
Inhibition of the sodium potassium adenosine triphosphatase pump sensitizes cancer cells to anoikis and prevents distant tumor formation.
Inhibition of tumor growth by an alkylation of the plasma membrane.
Intracellular accumulation of thallium as a marker of cisplatin cytotoxicity in nonsmall cell lung carcinoma: an application of inductively coupled plasma mass spectrometry.
Investigation of dose-dependent effects of berberine against renal ischemia/reperfusion injury in experimental diabetic rats.
Lymph node interdigitating cell sarcoma. A case report.
Malignant fibrous histiocytoma tumor cells resemble fibroblasts.
Mitophagy Induced by Mitochondrial Function Damage in Chicken Kidney Exposed to Cr(VI).
Morphologic and cytochemical properties of mouse liver neoplasms induced by diethylnitrosamine and promoted by 4,4'-dichlorodiphenyltrichloroethane, chlordane, or heptachlor.
Na+/K+-ATPase alpha subunits as new targets in anticancer therapy.
Na+/K+-ATPase and cancer.
Na+/K+-ATPase Revisited: On Its Mechanism of Action, Role in Cancer, and Activity Modulation.
Na+/K+-ATPase-Targeted Cytotoxicity of (+)-Digoxin and Several Semisynthetic Derivatives.
New 99mTc-Labeled Digitoxigenin Derivative for Cancer Cell Identification.
Nonspecifically enhanced therapeutic effects of vincristine on multidrug-resistant cancers when coencapsulated with quinine in liposomes.
One-megabase yeast artificial chromosome and 400-kilobase cosmid-phage contigs containing the von Hippel-Lindau tumor suppressor and Ca(2+)-transporting adenosine triphosphatase isoform 2 genes.
Ouabain induces apoptosis and autophagy in Burkitt's lymphoma Raji cells.
Oxidative Stress and Apoptotic Responses Elicited by Nostoc-Synthesized Silver Nanoparticles against Different Cancer Cell Lines.
Plumbagin-induced oxidative stress leads to inhibition of Na+/K+-ATPase (NKA) in canine cancer cells.
Polyamines secreted by cancer cells possibly account for the impairment of the human erythrocyte sodium pump activity.
Primary rhabdomyosarcoma of the cerebellum--a light, electron microscopic, and immunohistochemical study.
Quantification of ATP-producing and consuming processes of Ehrlich ascites tumour cells.
Quercetin inhibition of the induction and function of cytotoxic T lymphocytes.
Rabeprazole exhibits antiproliferative effects on human gastric cancer cell lines.
Sarcoma arising from interdigitating cells. Cytology and cytochemistry.
Serum and hepatic enzyme activity in rats treated with diethylnitrosamine.
Side population cells and drug resistance in breast cancer.
Sodium pump and Na+/H+ antiport restoration in erythrocytes from cancer patients in remission.
Steroid Glycosides Hyrcanoside and Deglucohyrcanoside: On Isolation, Structural Identification, and Anticancer Activity.
Structural Insights into the Interactions of Digoxin and Na+/K+-ATPase and Other Targets for the Inhibition of Cancer Cell Proliferation.
Suppressor cell activation and enhanced skin allograft survival after tumor promotor but not initiator induced depletion of cutaneous Langerhans cells.
Survival of detached cancer cells is regulated by movement of intracellular Na+,K+-ATPase.
Targeting FXYD2 by cardiac glycosides potently blocks tumor growth in ovarian clear cell carcinoma.
Thallium-201 chloride (Tl-201) accumulation and Na+/K+-ATPase expression in tumours of the head and neck.
The Effect of Curcumin Nanoparticles on Cisplatin-Induced Cardiotoxicity in Male Wistar Albino Rats.
The expression of the alpha1 subunit of Na+/K+-ATPase is related to tumor development and clinical outcomes in gastric cancer.
The fine structural localisation of thiamine pyrophosphatase and adenosine triphosphatase in neural tumours induced by N-ethyl-N-nitrosourea in rats.
The Sodium Pump alpha1 Subunit: a Disease Progression-Related Target for Metastatic Melanoma Treatment.
The vacuolar-type ATPase inhibitor archazolid increases tumor cell adhesion to endothelial cells by accumulating extracellular collagen.
Transgenic overexpression of translationally controlled tumor protein induces systemic hypertension via repression of Na+,K+-ATPase.
Treatment of ras-induced cancers by the F-actin-bundling drug MKT-077.
Tumor-associated a2 vacuolar ATPase acts as a key mediator of cancer-related inflammation by inducing pro-tumorigenic properties in monocytes.
Tumour blood flow for prediction of human prostate cancer aggressiveness: a study with Rubidium-82 PET, MRI and Na+/K+-ATPase-density.
Ultrastructural and cytochemical studies on hyperbasophilic foci with special reference to the demonstration of cell surface alterations in hepatocarcinogenesis.
Ultrastructural localization of membrane phosphatases in teratocarcinoma and early embryos.
UNBS1450 from Calotropis procera as a regulator of signaling pathways involved in proliferation and cell death.
Uncoupler-stimulated adenosine triphosphatase activity. Deficiency in intact mitochondria from Morris hepatomas and ascites tumor cells.
Update on the effects of the sodium pump ?1 subunit on human glioblastoma: from the laboratory to the clinic.
Vascular tumors of the mammary gland. A histochemical and ultrastructural study.
[A Simple Medical Research Microdevice for Analyzing Three-dimensional Migration of Tumor Cells in Vitro].
[Action of thymic lipid extract B on adenosine triphosphatase and succinate dehydrogenase of the liver of rats with Guerin tumors]
[Adenosine triphosphatase activity in the plasmatic membranes of cancer cells]
[Cancer cell-specific functional relation between Na+,K+-ATPase and volume-regulated anion channel].
[Cytomorphological and enzyme histological studies of bilaterally inoculated Dibromdulcit-sensitive and-resistent Yoshida tumors]
[Differential expression of 2 genes of the Na+,K+-AtPase subunit in normal and tumor tissues in humans]
[HCO3-stimulated adenosine triphosphatase in rat ovarian tumor cells]
[Histochemical and ultrastructural investigations on organ culture of malignant tumors (author's transl)]
[HISTOCHEMICAL DEMONSTRATION OF ADENOSINE TRIPHOSPHATASE ACTIVITY IN TRANSPLANTABLE TUMORS AND CORRESPONDING NORMAL TISSUES.]
[Na+,K+ -ATPase activity characteristics in human colon adenocarcinoma]
[Na+,K+-ATPase and Ca2+-ATPase isozymes in malignant neoplasms]
[Photodynamic effect of a hematoporphyrin derivative on the sodium pump activity and aerobic glycolysis in tumor cells]
[Significance of the inhibition of adenosine triphosphatase of the red splenic pulp during the development of tumor transplants in rats]
[The sodium pump could constitute a new target to combat glioblastomas]
[Ultracytochemical study of the nucleoside phosphatase activity of nuclei of epithelial cells of the gastric mucosa and of stomach cancer cells in humans]
Nephritis
Glomerulonephritis and sodium retention: enhancement of Na+/K+-ATPase activity in the collecting duct is shared by rats with puromycin induced nephrotic syndrome and mice with spontaneous lupus-like glomerulonephritis.
Nephrosis
Hyperaldosteronemia and activation of the epithelial sodium channel are not required for sodium retention in puromycin-induced nephrosis.
OBSERVATIONS OF RAT KIDNEY MITOCHONDRIAL ADENOSINE TRIPHOSPHATASE ACTIVITY DURING INDUCTION OF AMINONUCLEOSIDE NEPHROSIS.
Nephrotic Syndrome
Glomerulonephritis and sodium retention: enhancement of Na+/K+-ATPase activity in the collecting duct is shared by rats with puromycin induced nephrotic syndrome and mice with spontaneous lupus-like glomerulonephritis.
Hyperaldosteronemia and activation of the epithelial sodium channel are not required for sodium retention in puromycin-induced nephrosis.
Nephrotic syndrome: new concepts in the pathophysiology of sodium retention.
[Cellular and molecular mechanisms of sodium pump activation in experimental models of nephrotic syndrome]
Nervous System Diseases
A novel mitochondrial ATPase 6 point mutation in familial bilateral striatal necrosis.
Asparagine-905 of the mammalian phospholipid flippase ATP8A2 is essential for lipid substrate-induced activation of ATP8A2 dephosphorylation.
Decreased content of ascorbic acid (vitamin C) in the brain of knockout mouse models of Na+,K+-ATPase-related neurologic disorders.
Insights into the Pathology of the ?2-Na(+)/K(+)-ATPase in Neurological Disorders; Lessons from Animal Models.
Short-term block of Na+/K+-ATPase in neuro-glial cell cultures of cerebellum induces glutamate dependent damage of granule cells.
Specificity of biophysical and biochemical alterations in erythrocyte membranes in neurological disorders--Huntington's disease, Friedreich's ataxia, Alzheimer's disease, amyotrophic lateral sclerosis, and myotonic and duchenne muscular dystrophy.
The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence.
[The Na+,K+ pump continues to cause surprise]
Neuroblastoma
Acute changes in myo-inositol uptake and 22Na+ flux in murine neuroblastoma cells (N1E-115) following insulin.
Alterations of membrane integrity and cellular constituents by arachidonic acid in neuroblastoma and glioma cells.
Cilostazol, a cyclic AMP phosphodiesterase inhibitor, stimulates nitric oxide production and sodium potassium adenosine triphosphatase activity in SH-SY5Y human neuroblastoma cells.
Membrane regulation of the Na+,K+-ATPase during the neuroblastoma cell cycle: correlation with protein lateral mobility.
Ostreocin-D impact on globular actin of intact cells.
Reversal of hyperglycemic-induced defects in myo-inositol metabolism and Na+/K+ pump activity in cultured neuroblastoma cells by normalizing glucose levels.
Sodium pump alpha1 and alpha3 subunit isoforms mediate distinct responses to ouabain and are both essential for survival of human neuroblastoma.
Stimulation of the membrane-bound, magnesium-dependent adenosine triphosphatase of mouse neuroblastoma by concanavalin A and wheat germ agglutinin.
The chronic and acute effects of ethanol on adenosine triphosphatase activity in cultured astroblast and neuroblastoma cells.
[Rapid simultaneous isolation of microsomes and plasma membranes from neuroblastoma C 1300 N 18 cells]
Neurodegenerative Diseases
ATP7A (Menkes protein) functions in axonal targeting and synaptogenesis.
ATP7A gene addition to the choroid plexus results in long-term rescue of the lethal copper transport defect in a Menkes disease mouse model.
Copper homeostasis in the CNS: a novel link between the NMDA receptor and copper homeostasis in the hippocampus.
Functional expression of the menkes disease protein reveals common biochemical mechanisms among the copper-transporting P-type ATPases.
In vitro studies of the influence of glutamatergic agonists on the Na+,K+-ATPase and K+-p-nitrophenylphosphatase activities in the hippocampus and frontal cortex of rats.
Kynurenines impair energy metabolism in rat cerebral cortex.
L-Threo-Dihydroxyphenylserine corrects neurochemical abnormalities in a menkes disease mouse model.
Multi-angle development of therapeutic methods for Alzheimer's disease.
Possible involvement of membrane lipids peroxidation and oxidation of catalytically essential thiols of the cerebral transmembrane sodium pump as component mechanisms of iron-mediated oxidative stress-linked dysfunction of the pump's activity.
Safety of intracerebroventricular copper histidine in adult rats.
Neuroinflammatory Diseases
The ?2 Na+/K+-ATPase isoform mediates LPS-induced neuroinflammation.
Neuronal Ceroid-Lipofuscinoses
Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited ?-synuclein accumulation and age-dependent sensorimotor deficits.
Newcastle Disease
Adenosine triphosphatase associated with Newcastle disease virus. Conditions for its optimum activity.
Non-alcoholic Fatty Liver Disease
Phenotypic Alteration of Hepatocytes in Non-Alcoholic Fatty Liver Disease.
Obesity
A reproducible procedure for measuring sodium transport in cultured human fibroblasts from normal and obese donors.
Effects of obesity and estradiol on Na+/K+-ATPase and their relevance to cardiovascular diseases.
Endogenous digitalislike substance in an adult population in Japan.
Erythrocyte sodium pump activity in human obesity.
Erythrocyte sodium-potassium-stimulated adenosine triphosphatase activity is not related to obesity.
Hyperphagia and obesity in Na,K-ATPase alpha2 subunit-defective mice.
Is the erythrocyte sodium pump altered in human obesity?
Na+,K+-ATPase enzyme units in lean and obese (ob/ob) thyroxine-injected mice.
Obesity, thermogenesis and the sodium pump.
Reduced activity of the red-cell sodium-potassium pump in human obesity.
Reduced Na+, K+ -ATPase activity in intact red cells and isolated membranes from obese man.
Regulation of Na+/K+-ATPase by Estradiol and IGF-1 in Cardio-Metabolic Diseases.
The Cardiotonic Steroid Marinobufagenin Is a Predictor of Increased Left Ventricular Mass in Obesity: The African-PREDICT Study.
The effect of oral glucose on the leucocyte sodium pump in normal and obese subjects.
Transactivation of epidermal growth factor receptor in vascular and renal systems in rats with experimental hyperleptinemia: role in leptin-induced hypertension.
Two-dimensional, sex-specific autosomal linkage scan of the number of sodium pump sites.
Obstetric Labor, Premature
Alterations in uterine sodium pump abundance may contribute to the onset and progression of term and preterm labor in mice.
Oligospermia
Reduced activity of Mg2+- and Ca2+-dependent adenosine triphosphatase in seminal fluid of patients with oligozoospermia.
Ophthalmoplegia, Chronic Progressive External
A novel mitochondrial DNA deletion producing progressive external ophthalmoplegia associated with multiple sclerosis.
Optic Atrophy
ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.
Functional consequences of the CAPOS mutation E818K of Na+,K+-ATPase.
The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management.
The Influence of Na(+), K(+)-ATPase on Glutamate Signaling in Neurodegenerative Diseases and Senescence.
Osteoarthritis
Decreased NA+, K+-ATPase activity in erythrocyte membrane from rheumatoid arthritis patients.
The effects of osteoarthritis and age on skeletal muscle strength, Na+,K+-ATPase content, gene and isoform expression.
Osteosarcoma
Human osteogenic sarcoma: fine structural localization of adenosine triphosphatase.
Overweight
Leucocyte sodium content and sodium pump activity in overweight and lean hypertensives.
Peculiarities of the effects of bile acids on atpase activity of the colon mucosa in patients with overweight and irritable bowel syndrome.
The sodium pump and energy regulation: some new aspects for essential hypertension, diabetes II and severe overweight.
p-type na+ transporter deficiency
Exertional rhabdomyolysis in a patient with calcium adenosine triphosphatase deficiency.
Physiological suppression of a transport defect in Escherichia coli mutants deficient in Ca2+, Mg2+-stimulated adenosine triphosphatase.
Renal sodium- and potassium-activated adenosine triphosphatase deficiency during post-obstructive diuresis in the rat.
Sarcoplasmic reticulum adenosine triphosphatase deficiency with probable autosomal dominant inheritance.
p-type phospholipid transporter deficiency
Assessment of Adenosine Triphosphatase Phospholipid Transporting 8B1 (ATP8B1) Function in Patients With Cholestasis With ATP8B1 Deficiency by Using Peripheral Blood Monocyte-Derived Macrophages.
Folding defects in P-type ATP 8B1 associated with hereditary cholestasis are ameliorated by 4-phenylbutyrate.
In-silico Evaluation of Rare Codons and their Positions in the Structure of ATP8b1 Gene.
Pancreatitis, Chronic
Immunohistochemical localization of Na+, K+-ATPase in human normal and malignant pancreatic tissues.
Paralysis
A mutation of the Drosophila sodium pump alpha subunit gene results in bang-sensitive paralysis.
A novel ATP1A2 mutation in a patient with hypokalaemic periodic paralysis and CNS symptoms.
Arg16Gly polymorphism in beta2-adrenergic receptor gene is not associated with thyrotoxic periodic paralysis in Korean male patients with Graves' disease.
Diamphenethide--a reassessment of its pharmacological action.
Genistein: is the multifarious botanical a natural anthelmintic too?
In vivo and in vitro sodium pump activity in subjects with thyrotoxic periodic paralysis.
Intratympanic steroid injection as a first-line therapy in uremia patients with sudden sensorineural hearing loss.
Paramyxoviridae Infections
Na+/K+-ATPase as a Target of Cardiac Glycosides for the Treatment of SARS-CoV-2 Infection.
Parkinson Disease
Analysis of amplicon-based NGS data from neurological disease gene panels: a new method for allele drop-out management.
Genetic association study of the P-type ATPase ATP13A2 in late-onset Parkinson's disease.
Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.
Multi-angle development of therapeutic methods for Alzheimer's disease.
Parkinson's disease-associated human ATP13A2 (PARK9) deficiency causes zinc dyshomeostasis and mitochondrial dysfunction.
Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2.
Quinone and oxyradical scavenging properties of N-acetylcysteine prevent dopamine mediated inhibition of Na+, K+-ATPase and mitochondrial electron transport chain activity in rat brain: implications in the neuroprotective therapy of Parkinson's disease.
The human tongue slows down to speak: muscle fibers of the human tongue.
The strategic function of the P5-ATPase ATP13A2 in toxic waste disposal.
Parkinsonian Disorders
ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons.
ATP13A2 regulates mitochondrial bioenergetics through macroautophagy.
Characterization of cellular protective effects of ATP13A2/PARK9 expression and alterations resulting from pathogenic mutants.
Common pathogenic effects of missense mutations in the P-type ATPase ATP13A2 (PARK9) associated with early-onset parkinsonism.
Genome-wide screen for modifiers of Na + /K + ATPase alleles identifies critical genetic loci.
Hereditary parkinsonism with dementia is caused by mutations in ATP13A2, encoding a lysosomal type 5 P-type ATPase.
Hypothermia-induced dystonia and abnormal cerebellar activity in a mouse model with a single disease-mutation in the sodium-potassium pump.
Loss of P-type ATPase ATP13A2/PARK9 function induces general lysosomal deficiency and leads to Parkinson disease neurodegeneration.
Mutations Phe785Leu and Thr618Met in Na+,K+-ATPase, associated with familial rapid-onset dystonia parkinsonism, interfere with Na+ interaction by distinct mechanisms.
Pathogenic effects of novel mutations in the P-type ATPase ATP13A2 (PARK9) causing Kufor-Rakeb syndrome, a form of early-onset parkinsonism.
Protection against Mitochondrial and Metal Toxicity Depends on Functional Lipid Binding Sites in ATP13A2.
Rescue of Na+ Affinity in Aspartate-928 Mutants of Na+,K+-ATPase by Secondary Mutation of Glutamate-314.
Sodium Pumps Mediate Activity-Dependent Changes in Mammalian Motor Networks.
The structure of the Na+,K+-ATPase and mapping of isoform differences and disease-related mutations.
Pemphigus
[Adenosine triphosphatase activity in human skin under normal conditions and in chronic pemphigus]
Peptic Ulcer
Treatment of refractory peptic ulcer with omeprazole or continued H2 receptor antagonists: a controlled clinical trial.
Periapical Periodontitis
Apical periodontitis induces changes on oxidative stress parameters and increases Na+/K+-ATPase activity in adult rats.
Periodontitis
Comparative analysis of the effects of a novel vacuolar adenosine 5'-triphosphatase inhibitor, FR202126, and doxycycline on bone loss caused by experimental periodontitis in rats.
Peripheral Nervous System Diseases
Endoneurial ATPase activity in Tangier disease and other peripheral neuropathies.
Phenylketonurias
Alanine prevents the decrease of Na+,K+-ATPase activity in experimental phenylketonuria.
Effects of L-phenylalanine on acetylcholinesterase and Na+,K+-ATPase activities in suckling rat frontal cortex, hippocampus and hypothalamus.
Effects of phenylalanine and its deaminated metabolites on Na+,K+-ATPase activity in synaptosomes from rat brain.
In vivo effects of high phenylalanine blood levels on Na+,K+-ATPase, Mg2+-ATPase activities and biogenic amine concentrations in phenylketonuria.
Pheochromocytoma
Nerve growth factor induces Na+,K+-ATPase in a nerve cell line.
Photosensitivity Disorders
The effect of hypericin and hypocrellin-A on lipid membranes and membrane potential of 3T3 fibroblasts.
Placental Insufficiency
Complex, coordinated and highly regulated changes in placental signaling and nutrient transport capacity in IUGR.
Plasmacytoma
Specific involvement of calmodulin and non-specific effect of tropomyosin in the sensitivity to ouabain of Na+,K+-ATPase in murine plasmocytoma cells.
[Diagnosis of plasmocytoma using the adenosine triphosphatase reaction on bone marrow smears]
[The cutologic diagnosis of a plasmacytoma of a bone marrow smear by means of the adenosine triphosphatase reaction]
Pneumonia
Dynamic regulation of cardiolipin by the lipid pump Atp8b1 determines the severity of lung injury in experimental pneumonia.
Pulmonary inflammation and edema induced by phospholipase A2: global gene analysis and effects on aquaporins and Na+/K+-ATPase.
Pneumoperitoneum
The effects of sevoflurane and propofol anesthesia on renal sodium-potassium adenosine triphosphatase activity during pneumoperitoneum in rats.
Polycystic Kidney Diseases
A role for Na/K adenosine triphosphatase in the pathogenesis of cyst formation in experimental polycystic kidney disease.
Abnormal sodium pump distribution during renal tubulogenesis in congenital murine polycystic kidney disease.
Sodium pump distribution is not reversed in the DBA/2FG-pcy, polycystic kidney disease model mouse.
[Progressive reduction of alkaline phosphatase and of Mg-dependent adenosine triphosphatase (Mg-ATPase) in congenital polycystic kidney in PM/Se mice]
Polymicrogyria
ATP1A2- and ATP1A3-associated early profound epileptic encephalopathy and polymicrogyria.
Polyuria
The pathophysiology of septic shock: acute renal failure in rats following live E coli injection. A histochemical study of the proximal tubules.
Porcine Reproductive and Respiratory Syndrome
The effect of porcine reproductive and respiratory syndrome virus and porcine epidemic diarrhea virus challenge on growing pigs II: Intestinal integrity and function.
Potassium Deficiency
Adaptation of the cardiac muscle sodium pump to chronic potassium deficiency.
Pre-Eclampsia
Circulating bufodienolide and cardenolide sodium pump inhibitors in preeclampsia.
Digibind Reverses Inhibition of Cellular rb+ Uptake Caused by Endogenous Sodium Pump Inhibitors Present in Serum and Placenta of Women With Preeclampsia.
Digoxin Immune Fab Protects Endothelial Cells from Ouabain-Induced Barrier Injury.
Endogenous sodium pump inhibitors, diabetes mellitus and preeclampsia Preliminary observations and a hypothesis.
Erythrocyte sodium/potassium ATPase activity in severe preeclampsia.
Leucocyte electrolytes and sodium efflux rate constants in the hypertension of pre-eclampsia.
Marinobufagenin impairs first trimester cytotrophoblast differentiation.
Preeclampsia and calcium adenosine triphosphatase activity of red blood cell ghosts.
Preeclampsia, lipid peroxidation, and calcium adenosine triphosphatase activity of red blood cell ghosts.
Regulation of the sodium pump in pregnancy-related tissues in preeclampsia.
Sodium regulation, sodium pump function and sodium pump inhibitors in uncomplicated pregnancy and preeclampsia.
[Activities of respiratory chain enzymes in the etiology of preeclampsia]
Pregnancy, Prolonged
[Accumulation of actomyosin and its adenosine triphosphatase activity in the muscle of cervix uteri in prolonged pregnancy]
Pressure Ulcer
[Activity of adenosine triphosphatase and the expression of ryanodine receptor 1 mRNA in local tissue of pressure ulcer at early stage in gracilis of rats].
Prostatic Hyperplasia
[Enzymatic activities in human prostatic adenoma (leucine aminopeptidase, 5-nucleotidase, adenosine triphosphatase, lactic dehydrogenase, phosphohexoisomerase).]
Prostatic Neoplasms
Cytotoxicity of AMANTADIG - a semisynthetic digitoxigenin derivative - alone and in combination with docetaxel in human hormone-refractory prostate cancer cells and its effect on Na+/K+-ATPase inhibition.
Regulation of expression of Na+,K+-ATPase in androgen-dependent and androgen-independent prostate cancer.
Protein-Energy Malnutrition
Erythrocyte membrane Na+ and K+ activated adenosine triphosphatase in protein-calorie malnutrition.
Erythrocyte osmotic fragility in protein-energy malnutrition: cholesterol, phospholipid, and CA2+, Mg2+ adenosine triphosphatase.
Modified kinetics of erythrocyte membrane Na+-K+ adenosine triphosphatase in protein-energy malnutrition.
Oedema in protein energy malnutrition: the role of the sodium pump.
Pseudohypoaldosteronism
Erythrocyte Na+,K+-ATPase and nasal potential in pseudohypoaldosteronism.
Psoriasis
[Adenosine triphosphatase activity and Langerhans cells in psoriasis]
Pulmonary Arterial Hypertension
Pulmonary arterial hypertension in familial hemiplegic migraine with ATP1A2 channelopathy.
Pulmonary Disease, Chronic Obstructive
The heavy metal tolerant soil bacterium Achromobacter sp. AO22 contains a unique copper homeostasis locus and two mer operons.
[Reduced expression of the sarcoplasmic calcium pump SERCA2 in skeletal muscle from patients with chronic obstructive pulmonary disease and low body weight]
Pulmonary Edema
Modulation of pulmonary NA+ pump gene expression during cold storage and reperfusion.
Pulmonary edema clearance: juicing up the sodium pump.
Single dexamethasone injection increases alveolar fluid clearance in adult rats.
Upregulation of rat lung Na-K-ATPase during hyperoxic injury.
Pulmonary Sclerosing Hemangioma
Sclerosing hemangioma of the lung. An immunohistochemical study of intermediate filaments and endothelial markers.
Pyelonephritis
[Membrane-destabilizing processes as the universal basis of inflammation]
Renal Insufficiency
A labile sodium pump inhibitor from the peritoneal dialysate of hypertensive renal failure patients: estimates of potency.
Application of supercritical fluid chromatography to characterize a labile digitalis-like factor.
Biochemical abnormalities of platelets in renal failure. Evidence for decreased platelet serotonin, adenosine diphosphate and Mg-dependent adenosine triphosphatase.
Digoxin in the elderly and in renal failure. Contribution of erythrocyte 86-rubidium uptake tests.
Digoxin-like immunoreacting substance(s) in the serum of patients with chronic uremia.
Effects of acute and chronic uremia on active cation transport in rat myocardium.
Reduction of erythrocyte (Na(+)-K+) ATPase activities in non-insulin-dependent diabetic patients with hyperkalemia.
Sodium pump isoform specificity for the digitalis-like factor isolated from human peritoneal dialysate.
Renal Insufficiency, Chronic
Ca2+-Mg2+-dependent ATP-ase activity and calcium homeostasis in children with chronic kidney disease.
Decreased ouabain-sensitive adenosine triphosphatase activity in the erythrocyte membrame of patients with chronic renal disease.
Further biochemical characterization of an Na+ pump inhibitor purified from human urine.
Inhibition of Na+,K+-stimulated ATPase in the cochlea of the guinea pig. A potential cause of disturbed inner ear function in terminal renal failure.
[Effect of hemodialysis on erythrocyte acetylcholinesterase and adenosine triphosphatase activity in chronic renal insufficiency]
Reperfusion Injury
Antidigoxin antiserum prevents endogenous digitalis-like compound-mediated reperfusion injury via modulating sodium pump isoform gene expression.
Modulation of pulmonary NA+ pump gene expression during cold storage and reperfusion.
[Activity of ectoenzymes of the heart breaking up ATP in the period of myocardial reperfusion after ischemia]
Respiratory Distress Syndrome
Electroporation Mediated Gene Delivery of Na+,K+-ATPase and ENaC Subunits to the Lung Attenuates Acute Respiratory Distress Syndrome in a Two-Hit Porcine Model.
Regulation of alveolar epithelial function by hypoxia.
Retinitis Pigmentosa
High mitochondrial DNA T8993G mutation (<90%) without typical features of Leigh's and NARP syndromes.
Rhabdomyolysis
Altered fluid, electrolyte and mineral status in tropical disease, with an emphasis on malaria and leptospirosis.
Exertional rhabdomyolysis in a patient with calcium adenosine triphosphatase deficiency.
Rhabdomyosarcoma
Cholinergic stimulation of the Na+/K+ adenosine triphosphatase as revealed by microphysiometry.
Rhabdomyosarcoma, Alveolar
An evaluation of enzyme histochemistry in the diagnosis of childhood rhabdomyosarcoma.
Rheumatoid Nodule
A combined immunohistological and histochemical analysis of lymphocyte and macrophage subpopulations in the rheumatoid nodule.
Rhinitis, Allergic
Inhibition of the sodium, potassium adenosine triphosphatase enzyme in peripheral blood mononuclear cells of subjects with allergic rhinitis.
Rhinitis, Allergic, Seasonal
Quercetin inhibition of the induction and function of cytotoxic T lymphocytes.
Sarcoma
Adenosine triphosphatase activity of crystalline inclusions in alveolar soft part sarcoma. An ultrahistochemical study of a case.
An enzyme histochemical study of non-Hodgkin's lymphoma and allied disease.
Essential Oils, Pituranthos chloranthus and Teucrium ramosissimum, Chemosensitize Resistant Human Uterine Sarcoma MES-SA/Dx5 Cells to Doxorubicin by Inducing Apoptosis and Targeting P-Glycoprotein.
[Effect of dipin on the activity of water soluble adenosine triphosphatase in rats with sarcoma 45]
Sarcoma 180
CYTOCHEMICAL LOCALIZATION OF ADENOSINE TRIPHOSPHATASE IN THE MITOTIC APPARATUS OF HELA AND SARCOMA 180 TISSUE CULTURE CELLS.
Enzymatic responses of transplanted tumour cells towards estrogen, progesterone and testosterone.
Sarcoma, Alveolar Soft Part
Adenosine triphosphatase activity of crystalline inclusions in alveolar soft part sarcoma. An ultrahistochemical study of a case.
Sarcoma, Avian
Increased glucose uptake capacity of Rous-transformed cells and the relevance of deprivation derepression.
Sarcoma, Kaposi
HISTOCHEMISTRY OF KAPOSI'S SARCOMA. II. CHOLINESTERASES, MONOAMINE OXIDASE, AND ADENOSINE TRIPHOSPHATASE.
Sarcoma, Synovial
Cellular differentiation of epithelioid sarcoma. An electron-microscopic, enzyme-histochemical, and immunohistochemical study.
Sarcoma, Yoshida
Increase of adenosine triphosphatase activity of Yoshida sarcoma cells in the process of acquiring resistance to alkylating agents.
Scoliosis
Muscle spindles in the paraspinal musculature of patients with adolescent idiopathic scoliosis.
Seizures
A novel ATP1A2 variant associated with severe stepwise regression, hemiplegia, epilepsy and movement disorders in two unrelated patients.
A novel de novo nonsense mutation in ATP1A2 associated with sporadic hemiplegic migraine and epileptic seizures.
A Wide Clinical Phenotype Spectrum in Patients With ATP1A2 Mutations.
Assessment of neuropharmacological potential of low molecular weight components extracted from Rhinella schneideri toad poison.
Cortical Na+,K+-ATPase of immature rats following bicuculline-induced seizures.
Diphenyl diselenide-induced seizures in rat pups: possible interaction with glutamatergic system.
Early Treatment in Acute Severe Encephalopathy Caused by ATP1A2 Mutation of Familial Hemiplegic Migraine Type 2: Case Report and Literature Review.
Genetics of the epilepsies.
Genome-wide screen for modifiers of Na + /K + ATPase alleles identifies critical genetic loci.
GM1 ganglioside prevents seizures, Na+,K+-ATPase activity inhibition and oxidative stress induced by glutaric acid and pentylenetetrazole.
Increased activity of the sodium-plus-potassium ion-stimulated adenosine triphosphatase in rat brain during electrically induced convulsions.
Intrastriatal methylmalonic acid administration induces convulsions and TBARS production, and alters Na+,K+-ATPase activity in the rat striatum and cerebral cortex.
Knock-in mouse model of alternating hemiplegia of childhood: behavioral and electrophysiologic characterization.
Knockout of sodium pump ?3 subunit gene (Atp1a3(-/-)) results in perinatal seizure and defective respiratory rhythm generation.
Linkage analysis and disease models in benign familial infantile seizures: a study of 16 families.
Lipoic Acid Alters delta-Aminolevulinic Dehydratase, Glutathione Peroxidase and Na+,K+-ATPase Activities and Glutathione-Reduced Levels in Rat Hippocampus After Pilocarpine-Induced Seizures.
Mutation in the glutamate transporter EAAT1 causes episodic ataxia, hemiplegia, and seizures.
No evidence of ATP1A2 involvement in 12 multiplex Italian families with benign familial infantile seizures.
Novel mutations in the Na+, K+-ATPase pump gene ATP1A2 associated with familial hemiplegic migraine and benign familial infantile convulsions.
Reduced ouabain binding to erythrocytes in epilepsy--evidence for a membrane abnormality.
Relationship between susceptibility to DMCM-induced generalized motor convulsions and low-affinity [3H]-ouabain binding in membranes in rat brain.
Sulfur - Containing Amino Acids Homocysteine And Taurine In Seizures: Current State Of The Art.
The effect of vanadate on Na+,K+-ATPase activity of mouse cerebral cortex during bicuculline-induced seizures.
Treadmill exercise protects against pentylenetetrazol-induced seizures and oxidative stress after traumatic brain injury.
Seizures, Febrile
Familial hemiplegic migraine is associated with febrile seizures in an FHM2 family with a novel de novo ATP1A2 mutation.
Shared mechanisms of epilepsy, migraine and affective disorders.
Sepsis
Glucocorticoid receptor antagonism by mifepristone alters phosphocreatine breakdown during sepsis.
Sepsis increases the plasma membrane content of alpha1 and alpha2 isoforms of Na+-K+ adenosine triphosphatase in rat skeletal muscle.
SERCA1 attenuates diaphragm relaxation and uptake rate of SERCA in rats with acute sepsis.
Severe Acute Respiratory Syndrome
Coronavirus interactions with the cellular autophagy machinery.
Shock, Septic
Myocardial sodium pump activity in endotoxin shock.
Sjogren's Syndrome
An immunocytochemical study of H+ ATPase in kidney transplant rejection.
Sleep Apnea, Obstructive
2B.03: URIC ACID LEVELS RELATED TO OBSTRUCTIVE SLEEP APNEA SYNDROME IN PATIENTS WITH HYPERTENSION FROM XINJIANG OF CHINA.
Association between uric acid levels and obstructive sleep apnea syndrome in a large epidemiological sample.
Muscle type of palatopharyngeal muscle in children with severe obstructive sleep apnea.
Sleep Deprivation
Glial-specific gene alterations associated with manic behaviors.
Na+/K+-ATPase and lipid peroxidation in forebrain cortex and hippocampus of sleep-deprived rats treated with therapeutic lithium concentration for different periods of time.
Norepinephrine-stimulated increase in Na+, K+-ATPase activity in the rat brain is mediated through alpha1A-adrenoceptor possibly by dephosphorylation of the enzyme.
Spastic Paraplegia, Hereditary
Linking axonal degeneration to microtubule remodeling by Spastin-mediated microtubule severing.
Three novel mutations of the spastin gene in Chinese patients with hereditary spastic paraplegia.
Spinal Cord Injuries
Influence of chronic and acute spinal cord injury on skeletal muscle Na+/K+-ATPase and phospholemman expression in humans.
Na+,K+-ATPase concentration and fiber type distribution after spinal cord injury.
The loss-of-function disease-mutation G301R in the Na(+)/K(+)-ATPase ?2 isoform decreases lesion volume and improves functional outcome after acute spinal cord injury in mice.
Squamous Cell Carcinoma of Head and Neck
Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a chemoresistance marker in human oral squamous cell carcinoma treated with cisplatin.
Starvation
A chimeric Anabaena/ Escherichia coli KdpD protein (Anacoli KdpD) functionally interacts with E. coli KdpE and activates kdp expression in E. coli.
Effects of starvation, feeding, and time of day on the activity of proton transport adenosine triphosphatase in the parietal cells of the mouse gastric glands.
Functional analysis of McSnRK1 (SNF1-related protein kinase 1) in regulating Na/K homeostasis in transgenic cultured cells and roots of halophyte Mesembryanthemum crystallinum.
Increased glucose uptake capacity of Rous-transformed cells and the relevance of deprivation derepression.
Interaction between the autophagy protein Beclin 1 and Na+,K+-ATPase during starvation, exercise, and ischemia.
Mg2+ deprivation elicits rapid Ca2+ uptake and activates Ca2+/calcineurin signaling in Saccharomyces cerevisiae.
Pma1 is an alkali/alkaline earth metal cation ATPase that preferentially transports Na(+) and K(+) across the Mycobacterium smegmatis plasma membrane.
Sodium chloride-induced volume changes of freshwater cyanobacterium Synechococcus sp. PCC 7942 cells can be probed by chlorophyll a fluorescence.
[Na,K-ATPase activity of erythrocytes of rats during prolonged starvation].
Status Epilepticus
Enzyme histochemistry of the rat hippocampus during experimental status epilepticus.
Long-term decrease in Na+,K+-ATPase activity after pilocarpine-induced status epilepticus is associated with nitration of its alpha subunit.
The role of spreading depression, spreading depolarization and spreading ischemia in neurological disease.
Stomach Neoplasms
Differential sensitivity of human gastric cancer ATPase and normal gastric mucosa ATPase to the synthetic mammalian lignan analogue 2,3-dibenzylbutane-1,4-diol (hattalin).
Rabeprazole exhibits antiproliferative effects on human gastric cancer cell lines.
The expression of the alpha1 subunit of Na+/K+-ATPase is related to tumor development and clinical outcomes in gastric cancer.
Stomach Ulcer
Potassium bromate cytotoxicity in the Wister rat model of chronic gastric ulcers: Possible reversal by protocatechuic acid.
Stroke
Bone Marrow Mononuclear Cells Transplantation and Training Increased Transplantation of Energy Source Transporters in Chronic Stroke.
Marinobufagenin may mediate the impact of salty diets on left ventricular hypertrophy by disrupting the protective function of coronary microvascular endothelium.
Polymorphisms in migraine-associated gene, atp1a2, and ischemic stroke risk in a biracial population: the genetics of early onset stroke study.
Sporadic Hemiplegic Migraine with ATP1A2 and Prothrombin Gene Mutations.
Tachycardia
[Cancer cell-specific functional relation between Na+,K+-ATPase and volume-regulated anion channel].
Talipes Cavus
Functional consequences of the CAPOS mutation E818K of Na+,K+-ATPase.
The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management.
Tangier Disease
Endoneurial ATPase activity in Tangier disease and other peripheral neuropathies.
Teratocarcinoma
Cloning, expression, and chromosomal mapping of a human ATPase II gene, member of the third subfamily of P-type ATPases and orthologous to the presumed bovine and murine aminophospholipid translocase.
Ultrastructural localization of membrane phosphatases in teratocarcinoma and early embryos.
Tetanus
Inhibition of vacuolar adenosine triphosphatase antagonizes the effects of clostridial neurotoxins but not phospholipase A2 neurotoxins.
Muscle and serum adenosine triphosphatase in patients suffering from tetanus.
Post-tetanic spontaneous spike activity in rat sympathetic neurons exposed to low potassium ion concentration.
Thyroid Diseases
Erythrocyte sodium/potassium adenosine triphosphatase in thyroid disease and nonthyroidal illness.
Ion flux and Na+,K+-ATPase activity of erythrocytes and leucocytes in thyroid disease.
Thyrotoxicosis
Stimulation of cardiac myosin adenosine triphosphatase in thyrotoxicosis.
Trauma, Nervous System
The Na, K-ATPase alpha3-isoform specifically localizes in the Schmidt-Lanterman incisures of human nerve.
Tremor
Effects of L-phenylalanine on acetylcholinesterase and Na+,K+-ATPase activities in suckling rat frontal cortex, hippocampus and hypothalamus.
Tuberculosis
CtpA, a putative Mycobacterium tuberculosis P-type ATPase, is stimulated by copper (I) in the mycobacterial plasma membrane.
CtpB is a plasma membrane copper (I) transporting P-type ATPase of Mycobacterium tuberculosis.
Mycobacterium tuberculosis expresses a novel pH-dependent divalent cation transporter belonging to the Nramp family.
Pma1 is an alkali/alkaline earth metal cation ATPase that preferentially transports Na(+) and K(+) across the Mycobacterium smegmatis plasma membrane.
The P-type ATPase CtpF is a plasma membrane transporter mediating calcium efflux in Mycobacterium tuberculosis cells.
Uremia
An Na, K ATPase inhibitor from ultrafiltrate obtained by hemodialysis of patients with uremia.
Arginase activity of human erythrocyte ghosts in uremia.
Effect of chronic renal failure on Na,K-ATPase alpha 1 and alpha 2 mRNA transcription in rat skeletal muscle.
Effects of acute and chronic uremia on active cation transport in rat myocardium.
Intratympanic steroid injection as a first-line therapy in uremia patients with sudden sensorineural hearing loss.
Zinc and the sodium pump in uremia.
Urinary Bladder Neck Obstruction
Enhanced force generation by corpus cavernosum smooth muscle in rabbits with partial bladder outlet obstruction.
Urinary Bladder Neoplasms
Bufalin induced apoptosis of bladder carcinoma cells through the inactivation of Na+K+-ATPase.
Uterine Cervical Neoplasms
[Histoenzymatic studies on the behavior of succinic acid dehydrogenase, NADH-2-tetrazolium reductase, adenosine triphosphatase and alkaline phosphatase in cases of uterine cervix cancer]
Vascular System Injuries
Perivascular Delivery of Blebbistatin Reduces Neointimal Hyperplasia Following Carotid Injury in the Mouse.
Ventricular Fibrillation
Digitalis toxicity: lack of marked effect on brain na+,k+-adenosine triphosphatase in the cat.
Vertigo
Migrainous vertigo: mutation analysis of the candidate genes CACNA1A, ATP1A2, SCN1A, and CACNB4.
Vibrio Infections
Evidence for disruption of Na(+)-K(+)-ATPase and hsp70 during vibriosis of sea bream, Sparus (=Rhabdosargus) sarba Forsskål.
Virus Diseases
Alterations in monovalent cation transport in Sindbis virus-infected chick cells.
Glycolytic control of vacuolar-type ATPase activity: A mechanism to regulate influenza viral infection.
Visna
Adenosine triphosphatase activity during fusion of cultured sheep choroid plexus cells induced by either visna virus or polyethylene glycol.
Werner Syndrome
Diverse dealings of the Werner helicase/nuclease.
Whooping Cough
Angiotensin II AT1 receptor/signaling mechanisms in the biphasic effect of the peptide on proximal tubular Na+,K+-ATPase.
Colony-stimulating factor 1-induced Na+ influx into human monocytes involves activation of a pertussis toxin-sensitive GTP-binding protein.
Salt intake and intestinal dopaminergic activity in adult and old Fischer 344 rats.
Seminal fluid factor increases the resistance of the tight junctional complex of cultured human cervical epithelium CaSki cells.
The use of the potential-sensitive fluorescent probe bisoxonol in mast cells.
Wolfram Syndrome
Sodium-potassium ATPase 1 subunit is a molecular partner of Wolframin, an endoplasmic reticulum protein involved in ER stress.
Wound Infection
Changes in erythrocyte membranes in burned rabbits.
Yellow Fever
Strong alkalinization in the anterior midgut of larval yellow fever mosquitoes (Aedes aegypti): involvement of luminal Na+/K+-ATPase.
Zenker Diverticulum
Morphology of the cricopharyngeal muscle in Zenker and control specimens.
Zika Virus Infection
Inhibition of Na+/K+ ATPase blocks Zika virus infection in mice.
Zollinger-Ellison Syndrome
Fulminant hepatic failure related to omeprazole.