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Disease on EC 7.2.2.1 - Na+-transporting two-sector ATPase

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DISEASE
TITLE OF PUBLICATION
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Acidosis
Lactic acidosis transiently increases metabolic rate of turtle myocytes.
Monkey cerebral arterial relaxation caused by hypercapnic acidosis and hypertonic bicarbonate.
Protection of reoxygenated cardiomyocytes against hypercontracture by inhibition of Na+/H+ exchange.
Atherosclerosis
Functional and histological changes in mesenteric arteries and aortas from monkeys fed a high cholesterol diet.
Cardiomegaly
Down-regulation of Na+ pump alpha 2 isoform in isoprenaline-induced cardiac hypertrophy in rat: evidence for increased receptor binding affinity but reduced inotropic potency of digoxin.
Modulation by chronic nifedipine of plasma atrial natriuretic peptide, cell Na+ transport and plasma volume in rats with renal hypertension.
Cholera
Adenosine reverses the stimulatory effect of angiotensin II on the renal Na+-ATPase activity through the A2 receptor.
Angiotensin II activates the ouabain-insensitive Na+-ATPase from renal proximal tubules through a G-protein.
Effect of adenosine on the ouabain-insensitive Na+-ATPase activity from basolateral membrane of the proximal tubule.
PKA-mediated effect of MAS receptor in counteracting angiotensin II-stimulated renal Na+-ATPase.
Stimulation of the proximal tubule Na+-ATPase activity by adenosine A(2A) receptor.
Contracture
Effects of angiotensin II on intracellular calcium and contracture in metabolically inhibited cardiomyocytes.
Cystic Fibrosis
Inhibition of Na+,K+-ATPase by interferon gamma down-regulates intestinal epithelial transport and barrier function.
Dehydration
Resistance of mTAL Na+-dependent transporters and collecting duct aquaporins to dehydration in 7-month-old rats.
Essential Hypertension
Na+ transport in hypertension.
Heart Failure
Sarcolemmal Na(+)-K(+)-ATPase activity in congestive heart failure due to myocardial infarction.
Hyperglycemia
Differential stimulation of Na+ pump activity by insulin and nitric oxide in rabbit aorta.
Hypersensitivity
Effect of Na+ pump suppression on reactivity of rat trachealis to cooling.
Hypertension
A low concentration of ouabain (0.18 microg/kg) enhances hypertension in spontaneously hypertensive rats by inhibiting the Na+ pump and activating the renin-angiotensin system.
Chronic treatment with nifedipine prevents development of hypertension and abnormal red cell Na+ transport in Dahl-S-rats.
Effects of small doses of ouabain on the arterial blood pressure of anesthetized hypertensive and normotensive rats.
How does salt retention raise blood pressure?
Modulation by chronic nifedipine of plasma atrial natriuretic peptide, cell Na+ transport and plasma volume in rats with renal hypertension.
Myocardial Na+-K+-ATPase activity and [3H]ouabain binding sites in hypertensive rats.
Regulation of renal ouabain-resistant Na+-ATPase by leptin, nitric oxide, reactive oxygen species, and cyclic nucleotides: implications for obesity-associated hypertension.
Renal molecular mechanisms underlying altered Na+ handling and genesis of hypertension during adulthood in prenatally undernourished rats.
Sodium pump activity and contraction of renal artery from spontaneously hypertensive rats.
[Na+/Ca2+ exchanger(NCX1) and salt-sensitive hypertension]
Hypertension, Renal
Investigations on the Na+, K+-pump in erythrocytes of patients with renal hypertension.
Hypotension
Flow thresholds for cerebral energy disturbance and Na+ pump failure as studied by in vivo 31P and 23Na nuclear magnetic resonance spectroscopy.
Hypothyroidism
Permissive effect of thyroid hormones on induction of rat colonic Na+ transport by aldosterone is not localised at the level of Na+ channel transcription.
Leishmaniasis, Cutaneous
Anti-parasitic effect of the diuretic and Na+-ATPAse inhibitor furosemide in cutaneous leishmaniasis.
Microvascular Angina
Decreased activity of the red blood cell ATPase-dependent Na+ pump in patients with cardiac syndrome X.
Myocardial Infarction
Sarcolemmal Na(+)-K(+)-ATPase activity in congestive heart failure due to myocardial infarction.
Neoplasms
Equilibrium and steady-state models of the coupling between the amino acid gradient and the sodium electrochemical gradient in mouse ascites- tumour cells.
Phosphorylation of the beta subunit of Na+K+-ATPase in Ehrlich ascites tumor by a membrane-bound protein kinase.
Neuroblastoma
Inhibition of Na+, K+-ATPase activates swelling-induced taurine efflux in a human neuroblastoma cell line.
Paralysis
[3H]ouabain binding in skeletal muscle from horses with hyperkalemic periodic paralysis.
Paralysis, Hyperkalemic Periodic
[3H]ouabain binding in skeletal muscle from horses with hyperkalemic periodic paralysis.
Pneumonia
The sodium ion translocating oxaloacetate decarboxylase of Klebsiella pneumoniae. Sequence of the integral membrane-bound subunits beta and gamma.
Renal Insufficiency, Chronic
Investigations on the Na+, K+-pump in erythrocytes of patients with renal hypertension.
Tuberculosis, Multidrug-Resistant
Bio-layer interferometry for measuring kinetics of protein-protein interactions and allosteric ligand effects.
Vaccinia
Translational regulation of Na,K-ATPase alpha1 and beta1 polypeptide expression in epithelial cells.
Virus Diseases
Inhibition of Na+K+ATPase activity in membranes of Sindbis virus-infected chick cells.