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Information on EC 6.5.1.B3 - 2'-5' RNA ligase (GTP-activated)

for references in articles please use BRENDA:EC6.5.1.B3
preliminary BRENDA-supplied EC number
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The expected taxonomic range for this enzyme is: Pyrococcus
Reaction Schemes
a 3'-half-tRNA molecule with a 5'-oH end
+
a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end
=
a mature tRNA molecule containing a 2'-5'-phosphodiester bond
Synonyms
pf0027, ph0099, gtp-dependent rna ligase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
a 3'-half-tRNA molecule with a 5'-oH end + a 5'-half-tRNA molecule with a 2',3'-cyclic phosphate end = a mature tRNA molecule containing a 2'-5'-phosphodiester bond
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