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Information on EC 6.3.2.51 - phosphopantothenate-cysteine ligase (ATP)

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IUBMB Comments
A key enzyme in the production of coenzyme A. The eukaryotic enzyme requires ATP, in contrast to the bacterial enzyme, EC 6.3.2.5, phosphopantothenate---cysteine ligase, which requires CTP.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
4'-phosphopantothenoylcysteine synthetase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + (R)-4'-phosphopantothenate + L-cysteine = AMP + diphosphate + N-[(R)-4'-phosphopantothenoyl]-L-cysteine
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