Information on EC 18.104.22.168 - phosphopantothenate-cysteine ligase (ATP)for references in articles please use BRENDA:EC22.214.171.124
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A key enzyme in the production of coenzyme A. The eukaryotic enzyme requires ATP, in contrast to the bacterial enzyme, EC 126.96.36.199, phosphopantothenate---cysteine ligase, which requires CTP.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
4'-phosphopantothenoylcysteine synthetase, more
ATP + (R)-4'-phosphopantothenate + L-cysteine = AMP + diphosphate + N-[(R)-4'-phosphopantothenoyl]-L-cysteine
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