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Information on EC 6.3.2.37 - UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-D-lysine ligase

for references in articles please use BRENDA:EC6.3.2.37
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IUBMB Comments
Involved in the synthesis of cell-wall peptidoglycan. The D-lysine is attached to the peptide chain at the N6 position. The enzyme from Thermotoga maritima also performs the reaction of EC 6.3.2.7, UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---L-lysine ligase.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota
Synonyms
D-lysine-adding enzyme, MurE, MurE synthetase, UDP-MurNAc-L-Ala-D-Glu:D-Lys ligase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate + D-lysine = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-Nepsilon-D-lysine
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