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Disease on EC 6.3.1.1 - aspartate-ammonia ligase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma
Asparagine Synthetase Expression and Phase I Study With L-Asparaginase Encapsulated in Red Blood Cells in Patients With Pancreatic Adenocarcinoma.
arylsulfatase (type i) deficiency
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
aspartate-ammonia ligase deficiency
A novel compound heterozygous missense mutation in ASNS broadens the spectrum of asparagine synthetase deficiency.
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Asparagine Synthetase Deficiency causes reduced proliferation of cells under conditions of limited asparagine.
Asparagine synthetase deficiency detected by whole exome sequencing causes congenital microcephaly, epileptic encephalopathy and psychomotor delay.
Asparagine Synthetase Deficiency with Intracranial Hemorrhage Can Mimic Molybdenum Cofactor Deficiency.
Asparagine Synthetase deficiency-report of a novel mutation and review of literature.
Asparagine synthetase deficiency: A novel case with an unusual molecular mechanism.
Asparagine Synthetase Deficiency: New Inborn Errors of Metabolism.
Characterization of a novel variant in siblings with Asparagine Synthetase Deficiency.
Clinical outcomes of two patients with a novel pathogenic variant in ASNS: response to asparagine supplementation and review of the literature.
Clinical whole exome sequencing from dried blood spot identifies novel genetic defect underlying asparagine synthetase deficiency.
Clinical, molecular, and biochemical delineation of asparagine synthetase deficiency in Saudi cohort.
Congenital microcephaly with early onset epileptic encephalopathy caused by ASNS gene mutation: A case report.
Cyst-Peritoneal Shunt for the Treatment of a Progressive Intracerebral Cyst Associated with ASNS Mutation: Case Report and Literature Review.
Diaphragmatic Eventration in Sisters with Asparagine Synthetase Deficiency: A Novel Homozygous ASNS Mutation and Expanded Phenotype.
Effects of A6E Mutation on Protein Expression and Supramolecular Assembly of Yeast Asparagine Synthetase.
Epileptic encephalopathy with microcephaly in a patient with asparagine synthetase deficiency: a video-EEG report.
Fetal MRI and ultrasound findings of a confirmed asparagine synthetase deficiency case.
Generation of four induced pluripotent stem cell lines, GZWWTi001-A, GZWTZi001-A, GZWXYi001-A, and GZWXDi001-A, derived from peripheral blood mononuclear cells from a family with asparagine synthetase deficiency.
Hyperekplexia, microcephaly and simplified gyral pattern caused by novel ASNS mutations, case report.
In vitro functional analysis of four variants of human asparagine synthetase.
Report of four novel variants in ASNS causing asparagine synthetase deficiency and review of literature.
The first report of Japanese patients with asparagine synthetase deficiency.
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Brain Diseases
Asparagine synthetase deficiency detected by whole exome sequencing causes congenital microcephaly, epileptic encephalopathy and psychomotor delay.
Asparagine synthetase deficiency: A novel case with an unusual molecular mechanism.
Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy.
Diaphragmatic Eventration in Sisters with Asparagine Synthetase Deficiency: A Novel Homozygous ASNS Mutation and Expanded Phenotype.
Epileptic encephalopathy with microcephaly in a patient with asparagine synthetase deficiency: a video-EEG report.
Brain Edema
Asparagine Synthetase Deficiency with Intracranial Hemorrhage Can Mimic Molybdenum Cofactor Deficiency.
Breast Neoplasms
Down-Regulation of Asparagine Synthetase Induces Cell Cycle Arrest and Inhibits Cell Proliferation of Breast Cancer.
High Expression of Asparagine Synthetase Is Associated with Poor Prognosis of Breast Cancer in Chinese Population.
High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity.
Carcinoma
Enhanced expression of asparagine synthetase under glucose-deprived conditions promotes esophageal squamous cell carcinoma development.
Carcinoma, Hepatocellular
Alignment of the Transcription Start Site Coincides with Increased Transcriptional Activity from the Human Asparagine Synthetase Gene Following Amino Acid Deprivation of HepG2 Cells.
Asparagine synthetase is an independent predictor of surgical survival and a potential therapeutic target in hepatocellular carcinoma.
Hepatoblastoma: glutamine depletion hinders cell viability in the embryonal subtype but high GLUL expression is associated with better overall survival.
Polymorphism in asparagine synthetase is associated with overall survival of hepatocellular carcinoma patients.
Regulation of asparagine synthetase gene transcription by the basic region leucine zipper transcription factors ATF5 and CHOP.
Carcinoma, Non-Small-Cell Lung
Suppression of asparagine synthetase enhances the antitumor potency of ART and artemalogue SOMCL-14-221 in non-small cell lung cancer.
Carcinoma, Squamous Cell
Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.
Chordoma
Proteomics Analysis Identified ASNS as a Novel Biomarker for Predicting Recurrence of Skull Base Chordoma.
Colorectal Neoplasms
Metabolic Alterations Caused by KRAS Mutations in Colorectal Cancer Contribute to Cell Adaptation to Glutamine Depletion by Upregulation of Asparagine Synthetase.
Congenital Disorders of Glycosylation
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
A novel compound heterozygous missense mutation in ASNS broadens the spectrum of asparagine synthetase deficiency.
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Diaphragmatic Eventration
Diaphragmatic Eventration in Sisters with Asparagine Synthetase Deficiency: A Novel Homozygous ASNS Mutation and Expanded Phenotype.
Drug Resistant Epilepsy
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Epilepsy
Asparagine Synthetase Deficiency causes reduced proliferation of cells under conditions of limited asparagine.
Asparagine Synthetase Deficiency: New Inborn Errors of Metabolism.
Esophageal Squamous Cell Carcinoma
Enhanced expression of asparagine synthetase under glucose-deprived conditions promotes esophageal squamous cell carcinoma development.
Glioblastoma
Elevated Asparagine Biosynthesis Drives Brain Tumor Stem Cell Metabolic Plasticity and Resistance to Oxidative Stress.
Glioma
Clinical aggressiveness of malignant gliomas is linked to augmented metabolism of amino acids.
Metabolic plasticity of IDH1-mutant glioma cell lines is responsible for low sensitivity to glutaminase inhibition.
Glycogen Storage Disease
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Hepatoblastoma
Hepatoblastoma: glutamine depletion hinders cell viability in the embryonal subtype but high GLUL expression is associated with better overall survival.
Hyperekplexia
Hyperekplexia, microcephaly and simplified gyral pattern caused by novel ASNS mutations, case report.
Hyperglycinemia, Nonketotic
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Hypersensitivity
Polymorphisms of asparaginase pathway and asparaginase-related complications in children with acute lymphoblastic leukemia.
Hypophosphatasia
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Infections
Alterations in metabolic pathways in gastric epithelial cells infected with Helicobacter pylori.
Modulating plant primary amino acid metabolism as a necrotrophic virulence strategy: The immune-regulatory role of asparagine synthetase in Botrytis cinerea-tomato interaction.
Intellectual Disability
Asparagine Synthetase Deficiency causes reduced proliferation of cells under conditions of limited asparagine.
Intracranial Hemorrhages
Asparagine Synthetase Deficiency with Intracranial Hemorrhage Can Mimic Molybdenum Cofactor Deficiency.
Leukemia
A sulfoximine-based inhibitor of human asparagine synthetase kills l-asparaginase-resistant leukemia cells.
Amino acid control of asparagine synthetase: relation to asparaginase resistance in human leukemia cells.
Aminomalonic acid and its congeners as potential in vivo inhibitors of L-asparagine synthetase.
An inhibitor of human asparagine synthetase suppresses proliferation of an L-asparaginase-resistant leukemia cell line.
An investigation into the mechanism ofL-asparaginase resistance in L5178Y murine leukemia cells.
Asparagine synthetase activity of mouse leukemias.
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.
Asparagine synthetase expression is associated with the sensitivity to asparaginase in extranodal natural killer/T-cell lymphoma in vivo and in vitro.
Association of allele-specific methylation of the ASNS gene with asparaginase sensitivity and prognosis in T-ALL.
ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia.
Declined asparagine synthetase mRNA expression and enhanced sensitivity to asparaginase in HL-60 cells committed to monocytic differentiation.
Decrease in asparagine synthetase activity during cell differentiation of mouse and human leukemia cell lines.
Enzymatic and nutritional evidence for two-stage exression of the asparagine synthetase locus in L5178y murine leukemia mutants.
Evaluation of the asparagine synthetase level in leukemia cells by monoclonal antibodies.
Inhibitors of L-asparagine synthetase, in vitro.
L-Asparagine synthetase in serum as a marker for neoplasia.
Mass spectrometric quantification of asparagine synthetase in circulating leukemia cells from acute lymphoblastic leukemia patients.
Sequential high-dose ara-C and asparaginase versus high-dose ara-C alone in the treatment of patients with relapsed and refractory acute leukemias.
Triazolo[4,5-d]pyrimidines as Validated General Control Nonderepressible 2 (GCN2) Protein Kinase Inhibitors Reduce Growth of Leukemia Cells.
[Asparagine synthetase activity of leukocytes in acute leukemia]
Leukemia, Myeloid
Decrease in asparagine synthetase activity during cell differentiation of mouse and human leukemia cell lines.
Leukemia, Myeloid, Acute
Red blood cell-encapsulated L-asparaginase: potential therapy of patients with asparagine synthetase deficient acute myeloid leukemia.
Liver Neoplasms, Experimental
5-Carboxamido-4-amino-3-isoxazolidone, and asparagine analogue.
Potential inhibitors of L-asparagine biosynthesis. 2. Chemistry and biological activity of beta-hydroxyaspartic acid and its derivatives.
Potential inhibitors of L-asparagine biosynthesis. 5. Electrophilic amide analogues of (S)-2,3-diaminopropionic acid.
Purification and properties of asparagine synthetase from rat liver.
Lung Neoplasms
Loss of asparagine synthetase suppresses the growth of human lung cancer cells by arresting cell cycle at G0/G1 phase.
Suppression of asparagine synthetase enhances the antitumor potency of ART and artemalogue SOMCL-14-221 in non-small cell lung cancer.
Lymphoma
Asparagine synthetase expression and its potential prognostic value in patients with NK/T cell lymphoma.
Asparagine synthetase expression is associated with the sensitivity to asparaginase in extranodal natural killer/T-cell lymphoma in vivo and in vitro.
Asparagine synthetase in asparaginase resistant and susceptible mouse lymphomas.
Hypermethylation of CpG islands in the mouse asparagine synthetase gene: relationship to asparaginase sensitivity in lymphoma cells. Partial methylation in normal cells.
L-asparaginyl-tRNA synthetase and L-asparagine synthetase activities of L-asparaginase-sensitive and -resistant forms of the mouse Gardner lymphoma 6C3HED.
Selective apoptosis of natural killer-cell tumours by l-asparaginase.
Some properties of L-asparagine synthetase of the L-asparaginase-resistant mouse lymphoma 6C3HED [proceedings]
[Expression of asparagine synthetase in relapsed or refractory extranodal NK/T cell lymphoma].
Lysosomal Storage Diseases
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Melanoma
Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.
Translational reprogramming marks adaptation to asparagine restriction in cancer.
Metabolism, Inborn Errors
Asparagine Synthetase Deficiency: New Inborn Errors of Metabolism.
Microcephaly
A novel compound heterozygous missense mutation in ASNS broadens the spectrum of asparagine synthetase deficiency.
Asparagine synthetase deficiency detected by whole exome sequencing causes congenital microcephaly, epileptic encephalopathy and psychomotor delay.
Asparagine Synthetase Deficiency with Intracranial Hemorrhage Can Mimic Molybdenum Cofactor Deficiency.
Asparagine synthetase deficiency: A novel case with an unusual molecular mechanism.
Asparagine Synthetase Deficiency: New Inborn Errors of Metabolism.
Deficiency of asparagine synthetase causes congenital microcephaly and a progressive form of encephalopathy.
Diaphragmatic Eventration in Sisters with Asparagine Synthetase Deficiency: A Novel Homozygous ASNS Mutation and Expanded Phenotype.
Epileptic encephalopathy with microcephaly in a patient with asparagine synthetase deficiency: a video-EEG report.
Hyperekplexia, microcephaly and simplified gyral pattern caused by novel ASNS mutations, case report.
Novel Mutations in the Asparagine Synthetase Gene (ASNS) Associated With Microcephaly.
The first report of Japanese patients with asparagine synthetase deficiency.
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Muscle Spasticity
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Muscular Atrophy
Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury.
Muscular Diseases
Progressive Degenerative Myopathy and Myosteatosis in ASNSD1-Deficient Mice.
Nasopharyngeal Carcinoma
Overexpression of Asparagine Synthetase and Matrix Metalloproteinase 19 Confers Cisplatin Sensitivity in Nasopharyngeal Carcinoma Cells.
Neoplasm Metastasis
Asparagine bioavailability governs metastasis in a model of breast cancer.
Asparagine Synthetase Expression and Phase I Study With L-Asparaginase Encapsulated in Red Blood Cells in Patients With Pancreatic Adenocarcinoma.
L-Asparagine synthetase: a marker for metastases.
Neoplasms
Amino acids signatures of distance-related surgical margins of oral squamous cell carcinoma.
Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction.
Asparagine bioavailability governs metastasis in a model of breast cancer.
Asparagine Depletion Potentiates the Cytotoxic Effect of Chemotherapy Against Brain Tumors.
Asparagine plays a critical role in regulating cellular adaptation to glutamine depletion.
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.
Asparagine synthetase expression and its potential prognostic value in patients with NK/T cell lymphoma.
Asparagine Synthetase Expression and Phase I Study With L-Asparaginase Encapsulated in Red Blood Cells in Patients With Pancreatic Adenocarcinoma.
Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia.
Asparagine synthetase in normal and malignant tissues: correlation with tumor sensitivity to asparaginase.
Asparagine Synthetase: Regulation by Cell Stress and Involvement in Tumor Biology.
Canagliflozin Improves Liver Function in Rats by Upregulating Asparagine Synthetase.
Consumption of meat containing ractopamine might enhance tumor growth through induction of asparagine synthetase.
Discovery of why acute lymphoblastic leukaemia cells are killed by asparaginase: Adventures of a young post-doctoral student, Bertha K Madras.
Down-Regulation of Asparagine Synthetase Induces Cell Cycle Arrest and Inhibits Cell Proliferation of Breast Cancer.
Effects of asparagine synthetase inhibitors on asparaginase resistant tumors.
Glutamine-dependent asparagine synthetase in fetal, adult and neoplastic rat tissues.
High-resolution crystal structure of human asparagine synthetase enables analysis of inhibitor binding and selectivity.
Human asparagine synthetase associates with the mitotic spindle.
Incorporation of monoclonal antibodies into cells by osmotic permeabilization. Effect on cellular metabolism.
Inhibition of GCN2 sensitizes ASNS-low cancer cells to asparaginase by disrupting the amino acid response.
Inhibitors of L-asparagine synthetase, in vitro.
Interaction of the eucaryotic peptide chain initiation factor eIF-4A with the specific elements at the 5'-untranslated sequence of human asparagine synthetase mRNA.
Knockdown of asparagine synthetase (ASNS) suppresses cell proliferation and inhibits tumor growth in gastric cancer cells.
Knockdown of asparagine synthetase by RNAi suppresses cell growth in human melanoma cells and epidermoid carcinoma cells.
L-Asparagine synthetase in serum as a marker for neoplasia.
Microarray analysis uncovers retinoid targets in human bronchial epithelial cells.
Purification and properties of asparagine synthetase from rat liver.
Role of pancreatic L-asparagine synthetase in homeostasis of L-asparagine.
Sex Differences in Colon Cancer Metabolism Reveal A Novel Subphenotype.
Successful treatment with Erwinia L-asparaginase for recurrent natural killer/T cell lymphoma.
The glutaminase activity of L-asparaginase is not required for anticancer activity against ASNS-negative cells.
Transfer of monoclonal antibodies into mammalian cells by electroporation.
Translational reprogramming marks adaptation to asparagine restriction in cancer.
Ovarian Neoplasms
Asparagine Synthetase and Filamin A Have Different Roles in Ovarian Cancer.
Asparagine synthetase as a causal, predictive biomarker for L-asparaginase activity in ovarian cancer cells.
Asparagine synthetase is a predictive biomarker of L-asparaginase activity in ovarian cancer cell lines.
Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel.
Searching for pharmacogenomic markers: the synergy between omic and hypothesis-driven research.
Pancreatic Diseases
The role of asparagine synthetase on nutrient metabolism in pancreatic disease.
Pancreatic Neoplasms
Enhanced expression of asparagine synthetase under glucose-deprived conditions protects pancreatic cancer cells from apoptosis induced by glucose deprivation and cisplatin.
Pancreatitis
Polymorphisms of asparaginase pathway and asparaginase-related complications in children with acute lymphoblastic leukemia.
Paralysis
Cystathionine gamma-Lyase-deficient mice require dietary cysteine to protect against acute lethal myopathy and oxidative injury.
Peroxisomal Disorders
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Persistent Vegetative State
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Asparagine synthetase (ASNS) gene polymorphism is associated with the outcome of childhood acute lymphoblastic leukemia by affecting early response to treatment.
Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia.
Asparagine Synthetase in Cancer: Beyond Acute Lymphoblastic Leukemia.
Correlation between asparaginase sensitivity and asparagine synthetase protein content, but not mRNA, in acute lymphoblastic leukemia cell lines.
Efficient expression, purification, and characterization of C-terminally tagged, recombinant human asparagine synthetase.
Evaluation of the asparagine synthetase level in leukemia cells by monoclonal antibodies.
Functional analysis of a novel DNA polymorphism of a tandem repeated sequence in the asparagine synthetase gene in acute lymphoblastic leukemia cells.
Human asparagine synthetase associates with the mitotic spindle.
Hypomethylation and reactivation of the asparagine synthetase gene induced by L-asparaginase and ethyl methanesulfonate.
Mapping the aspartic acid binding site of Escherichia coli asparagine synthetase B using substrate analogs.
Mass spectrometric quantification of asparagine synthetase in circulating leukemia cells from acute lymphoblastic leukemia patients.
Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase.
Methylation analysis of asparagine synthetase gene in acute lymphoblastic leukemia cells.
Up-regulation of asparagine synthetase expression is not linked to the clinical response L-asparaginase in pediatric acute lymphoblastic leukemia.
[Asparagine synthetase activity in pediatric acute lymphoblastic leukemia]
[Study of the correlation between the expression level of asparagine synthetase and the outcome of children with acute lymphocytic leukemia]
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Epigenetic Silencing Affects l-Asparaginase Sensitivity and Predicts Outcome in T-ALL.
[Asparagine synthetase activity in pediatric acute lymphoblastic leukemia]
Prostatic Neoplasms
Integrative molecular profiling reveals asparagine synthetase is a target in castration-resistant prostate cancer.
pyruvate carboxylase deficiency
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Pyruvate Carboxylase Deficiency Disease
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
pyruvate dehydrogenase (nadp+) deficiency
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Pyruvate Dehydrogenase Complex Deficiency Disease
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.
Quadriplegia
A novel compound heterozygous missense mutation in ASNS broadens the spectrum of asparagine synthetase deficiency.
Asparagine Synthetase Deficiency: New Inborn Errors of Metabolism.
The first report of Japanese patients with asparagine synthetase deficiency.
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Rectal Neoplasms
Deficiency in asparagine synthetase expression in rectal cancers receiving concurrent chemoradiotherapy: negative prognostic impact and therapeutic relevance.
Sarcoma
Functional genomic screening reveals asparagine dependence as a metabolic vulnerability in sarcoma.
Isolation of human cDNAs for asparagine synthetase and expression in Jensen rat sarcoma cells.
Properties of asparagine synthetase in asparagine-independent variants of Jensen rat sarcoma cells induced by 5-azacytidine.
Sarcopenia
Progressive Degenerative Myopathy and Myosteatosis in ASNSD1-Deficient Mice.
Seizures
A novel compound heterozygous missense mutation in ASNS broadens the spectrum of asparagine synthetase deficiency.
Hyperekplexia, microcephaly and simplified gyral pattern caused by novel ASNS mutations, case report.
The first report of Japanese patients with asparagine synthetase deficiency.
Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency.
Starvation
Amino acids as regulators of gene expression: molecular mechanisms.
Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction.
Asparagine metabolism and nitrogen distribution during protein degradation in sugar-starved maize root tips.
Decrease in asparagine synthetase activity during cell differentiation of mouse and human leukemia cell lines.
EVI1 triggers metabolic reprogramming associated with leukemogenesis and increases sensitivity to L-asparaginase.
Expression of CsSEF1 gene encoding putative CCCH zinc finger protein is induced by defoliation and prolonged darkness in cucumber fruit.
Pancreatic tumor sensitivity to plasma L-asparagine starvation.
Regulation of asparagine synthetase gene expression by amino acid starvation.
The synergism of 6-mercaptopurine plus cytosine arabinoside followed by PEG-asparaginase in human leukemia cell lines (CCRF/CEM/0 and (CCRF/CEM/ara-C/7A) is due to increased cellular apoptosis.
TRB3 inhibits the transcriptional activation of stress-regulated genes by a negative feedback on the ATF4 pathway.
Stomach Neoplasms
Knockdown of asparagine synthetase (ASNS) suppresses cell proliferation and inhibits tumor growth in gastric cancer cells.
transaldolase deficiency
Antenatal manifestations of inborn errors of metabolism: autopsy findings suggestive of a metabolic disorder.