Reference on EC 6.1.1.20 - phenylalanine-tRNA ligase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Goldgur, Y.; Safro, M.
Aminoacyl-tRNA synthetases from Haloarcula marismortui: an evidence for a multienzyme complex in a procaryotic system
Biochem. Mol. Biol. Int.
32
1075-1083
1994
Haloarcula marismortui
Airas, R.K.
Differences in the magnesium dependences of the class I and class II aminoacyl-tRNA synthetases from Escherichia coli
Eur. J. Biochem.
240
223-231
1996
Escherichia coli
Zakharova, O.D.; Kotenko, I.; Lavrik, O.I.
Phenylalanyl-tRNA-synthetase from human placenta: isolation and characteristics
Biokhimiia
55
1025-1031
1990
Homo sapiens
Bobkova, E.V.; Volfson, A.D.; Ankilova, V.N.; Lavrik, O.I.
Separation and comparative characteristics of subunits of phenylalanyl-tRNA synthetase from Escherichia coli MRE-600 and Thermus thermophilus HB8
Biokhimiia
55
525-533
1990
Escherichia coli, Thermus thermophilus, Escherichia coli MRE 600, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Goldgur, Y.; Mosyak, L.; Reshetnikova, L.; Ankilova, V.; Lavrik, O.; Khodyreva, S.; Safro, M.
The crystal structure of phenylalanyl-tRNA synthetase from Thermus thermophilus complexed with tRNAPhe
Structure
5
59-68
1997
Thermus thermophilus
Vartanian, O.A.; Mashanov-Golikov, A.V.; Vol'fson, A.D.; Zakharova, O.D.; Lavrik, O.I.; Filonenko, V.V.; Beresten, S.F.
Express method of isolation of mammalian phenylalanine-tRNA synthetase and preparation of monoclonal antibodies against this enzyme
Mol. Biol. (Mosk.)
24
788-794
1990
Bos taurus
Ankilova, V.N.; Reshetnikova, L.S.; Chernaya, M.M.; Lavrik, O.I.
Phenylalanyl-tRNA synthetase from Thermus thermophilus HB8. Purification and properties of the crystallizing enzyme
FEBS Lett.
227
9-13
1988
Thermus thermophilus
-
Mosyak, L.; Reshetnikova, L.; Goldgur, Y.; Delarue, M.; Safro, M.G.
Structure of phenylalanyl-tRNA synthetase from Thermus thermophilus
Nat. Struct. Biol.
2
537-547
1995
Thermus thermophilus
Chernaya, M.M.; Korolev, S.V.; Reshetnikova, L.S.; Safro, M.G.
Preliminary crystallographic study of the phenylalanyl-tRNA synthetase from Thermus thermophilus HB8
J. Mol. Biol.
198
555-556
1987
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Fasiolo, F.; Sanni, A.; Potier, S.; Ebel, J.P.; Boulanger, Y.
Identification of the major tRNAPhe binding domain in the tetrameric structure of cytoplasmic phenylalanyl-tRNA synthetase from baker's yeast
FEBS Lett.
242
351-356
1989
Saccharomyces cerevisiae
Mosyak, L.; Safro, M.
Phenylalanyl-tRNA synthetase from Thermus thermophilus has four antiparallel folds of which only two are catalytically functional
Biochimie
75
1091-1098
1993
Thermus thermophilus
Roth, A.; Eriani, G.; Dirheimer, G.; Gangloff, J.
Kinetic properties of pure overproduced Bacillus subtilis phenylalanyl-tRNA synthetase do not favour in vivo inhibition by ochratoxin A
FEBS Lett.
326
87-91
1993
Bacillus subtilis
Stepanov, V.G.; Moor, N.A.; Ankilova, V.N.; Lavrik, O.I.
Phenylalanyl-tRNA synthetase from Thermus thermophilus can attach two molecules of phenylalanine to tRNAPhe
FEBS Lett.
311
192-194
1992
Thermus thermophilus
Khvorova, A.M.; Motorin, Y.A.; Wolfson, A.D.
Crucial role of pyrophosphate in the aminoacylation of E. coli tRNAPhe by yeast phenylalanyl-tRNA synthetase
FEBS Lett.
311
139-142
1992
Saccharomyces cerevisiae
Moor, N.A.; Ankilova, V.N.; Lavrik, O.I.
Recognition of tRNAPhe by phenylalanyl-tRNA synthetase of Thermus thermophilus
Eur. J. Biochem.
234
897-902
1995
Thermus thermophilus
Bobkova, E.V.; Mashanov-Golikov, A.V.; Wolfson, A.; Ankilova, V.N.; Lavrik, O.I.
Comparative study of subunits of phenylalanyl-tRNA synthetase from Escherichia coli and Thermus thermophilus
FEBS Lett.
290
95-98
1991
Escherichia coli, Thermus thermophilus
Bobkova, E.V.; Stepanov, V.G.; Lavrik, O.I.
A comparative study of the relationship between thermostability and function of phenylalanyl-tRNA synthetase from Escherichia coli and Thermus thermophilus
FEBS Lett.
302
54-56
1992
Escherichia coli, Thermus thermophilus
Reshetnikova, L.; Chernaya, M.; Ankilova, V.; Lavrik, O.; Delarue, M.; Thierry, J.C.; Moras, D.; Safro, M.
Glycyl-tRNA synthetase: Three-dimensional structure of phenylalanyl-transfer RNA synthetase from Thermus thermophilus HB8 at 0.6-nm resolution
Eur. J. Biochem.
208
411-417
1992
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Kast, P.; Hennecke, H.
Amino acid substrate specificity of Escherichia coli phenylalanyl-tRNA synthetase altered by distinct mutations
J. Mol. Biol.
222
99-124
1991
Escherichia coli
Peterson, E.T.; Pan, T.; Coleman, J.; Uhlenbeck, O.C.
In vito selection of small RNAs that bind to Escherichia coli phenylalanyl-tRNA synthetase
J. Mol. Biol.
242
186-192
1994
Escherichia coli
Nazarenko, I.A.; Peterson, E.T.; Zakharova, O.D.; Lavrik, O.I.; Uhlenbeck, O.C.
Recognition nucleotides for human phenylalanyl-tRNA synthetase
Nucleic Acids Res.
20
475-478
1992
Homo sapiens
Sampson, J.R.; Behlen, L.S.; DiRenzo, A.B.; Uhlenbeck, O.C.
Recognition of yeast tRNAPhe by its cognate yeast phenylalanyl-tRNA synthetase: An analysis of specificity
Biochemistry
31
4161-4167
1992
Saccharomyces cerevisiae
Freist, W.; Sternbach, H.; Cramer, F.
Phenylalanyl-tRNA synthetase from yeast and its discrimination of 19 amino acids in aminoacylation of tRNAPhe-C-C-A and tRNAPhe-C-C-A(3'NH2)
Eur. J. Biochem.
240
526-531
1996
Saccharomyces cerevisiae
Hanke, T.; Bartmann, P.; Hennecke, H.; Kosakowski, H.M.; Jaenicke, R.; Holler, E.; Bck, A.
L-Phenylalanyl-tRNA synthetase of Escherichia coli K-10. A reinvestigation of molecular weight and subunit structure
Eur. J. Biochem.
43
601-607
1974
Escherichia coli, Escherichia coli K-10
Schiller, P.W.; Schechter, A.N.
Phenylalanyl-tRNA synthetase
Methods Enzymol.
34
513-516
1974
Salmonella enterica subsp. enterica serovar Typhimurium
Hossain, A.
Purification and properties of phenylalanyl-tRNA synthetase from baker's yeast
Can. J. Biochem.
53
1316-1322
1975
Saccharomyces cerevisiae
Pimmer, J.; Holler, E.
Mechanism of phenylalanyl-tRNA synthetase of Escherichia coli K 10. Modulation of catalytic properties by magnesium
Biochemistry
18
3714-3723
1979
Escherichia coli
Diatewa, M.; Stahl, A.J.C.
Purification and subunit structure of mitochondrial phenylalanyl-tRNA synthetase from yeast
Biochem. Biophys. Res. Commun.
94
189-198
1980
Saccharomyces cerevisiae
Swamy, G.S.; Pillay, D.T.N.
Purification and some properties of phenylalanyl-tRNA synthetase from soybean (Glycine max L.)
Plant Sci. Lett.
20
99-107
1980
Glycine max
-
Mayaux, J.F.; Blanquet, S.
Binding of zinc to Escherichia coli phenylalanyl transfer ribonucleic acid synthetase. Comparison with other aminoacyl transfer ribonucleic acid synthetases
Biochemistry
20
4647-4654
1981
Escherichia coli
Plateau, P.; Mayaux, J.F.; Blanquet, S.
Zinc(II)-dependent synthesis of diadenosine 5',5'''-P1,P4-tetraphosphate by Escherichia coli and yeast phenylalanyl transfer ribonucleic acid synthetases
Biochemistry
20
4654-4662
1981
Saccharomyces cerevisiae, Escherichia coli
Gabius, H.J.; Cramer, F.
Purification and subunit structure of phenylalanyl-tRNA synthetase from hen liver mitochondria
Biochem. Biophys. Res. Commun.
106
325-330
1982
Gallus gallus
Brevet, A.; Plateau, A.; Cirakoglu, B.; Pailliez, J.P.; Blanquet, S.
Zinc-dependent synthesis of 5',5'-diadenosine tetraphosphate by sheep liver lysyl- and phenylalanyl-tRNA synthetases
J. Biol. Chem.
257
14613-14615
1982
Ovis aries
Gabius, H.J.; Freist, W.; Cramer, F.
Phenylalanyl-tRNA synthetases from hen liver cytoplasm and mitochondria, yeast cytoplasm and mitochondria, and from Escherichia coli: substrate specificity relationship with regard to ATP analogs
Hoppe-Seyler's Z. Physiol. Chem.
363
1241-1246
1982
Saccharomyces cerevisiae, Gallus gallus, Escherichia coli
Gabius, H.J.; Cramer, F.
Phenylalanyl-tRNA synthetases from cytoplasm and mitochondria of yeast and hen liver: comparison of their structural and catalytic properties
Hoppe-Seyler's Z. Physiol. Chem.
363
1473-1481
1982
Saccharomyces cerevisiae, Gallus gallus
Gabius, H-J.; von der Haar, F.; Cramer, F.
Evolutionary aspects of accuracy of phenylalanyl-tRNA synthetase. A comparative study with enzymes from Escherichia coli, Saccharomyces cerevisiae, Neurospora crassa, and turkey liver using phenylalanine
Biochemistry
22
2331-2339
1983
Saccharomyces cerevisiae, Escherichia coli, Meleagris gallopavo, Neurospora crassa
Gabius, H.J.; Engelhardt, R.; Piel, N.; Sternbach, H.; Cramer, F.
Phenylalanyl-tRNA synthetase from yeast cytoplasm and mitochondria. The presence of a carbohydrate moiety in the mitochondrial enzyme and immunological evidence for structural relationship
Biochim. Biophys. Acta
743
451-454
1983
Saccharomyces cerevisiae
Goerlich, O.; Holler, E.
Phenylalanyl-tRNA synthetase of Escherichia coli K10. Effects of zinc(II) on partial reactions of diadenosine 5',5'''-P1,P4-tetraphosphate synthesis. Conformation, and protein aggregation
Biochemistry
23
182-190
1984
Escherichia coli, Escherichia coli K-10
Ducruix, A.; Hounwanou, N.; Reinbolt, J.; Boulanger, Y.; Blanquet, S.
Purification and reversible subunit dissociation of overproduced Escherichia coli phenylalanyl-tRNA synthetase
Biochim. Biophys. Acta
741
244-250
1983
Escherichia coli
Rauhut, R.; Gabius, H.J.; Cramer, F.
Purification and properties of phenylalanyl-tRNA synthetase from a higher plant (Phaseolus vulgaris)
Hoppe-Seyler's Z. Physiol. Chem.
365
289-296
1984
Phaseolus vulgaris
Rauhut, R.; Gabius, H.J.; Kuhn, W.; Cramer, F.
Phenylalanyl-tRNA synthetase from the archaebacterium Methanosarcina barkeri
J. Biol. Chem.
259
6340-6345
1984
Methanosarcina barkeri
Rauhut, R.; Gabius, H.J.; Engelhard, R.; Cramer, F.
Archaebacterial phenylalanyl-tRNA synthetase. Accuracy of the phenylalanyl-tRNA synthetase from the archaebacterium Methanosarcina barkeri. Zn(II)-dependent synthesis of diadenosine 5',5'''-tetraphosphate, and immunological relationship of phenylalanyl-tRNA synthetases from different urkingdoms
J. Biol. Chem.
260
182-187
1985
Methanosarcina barkeri
Rauhut, R.; Gabius, H.J.; Cramer, F.
Striking differences of physical properties for two different phenylalanyl-tRNA synthetases in Cyanophora paradoxa
FEMS Microbiol. Lett.
27
175-177
1985
Cyanophora paradoxa
-
Rauhut, R.; Gabius, H.J.; Cramer, F.
Evolutionary aspects of accuracy of phenylalanyl-tRNA synthetase. Accuracy of the cytoplasmic and chloroplastic enzymes of a higher plant (Phaseulos vulgaris)
Biochemistry
24
4052-4057
1985
Phaseolus vulgaris
Khodyreva, S.N.; Moor, N.A.; Ankilova, V.N.; Lavrik, O.I.
Phenylalanyl-tRNA synthetase from E. coli MRE-600: analysis of the active site distribution on the enzyme subunit by affinity labelling
Biochim. Biophys. Acta
830
206-212
1985
Escherichia coli, Escherichia coli MRE 600
Rauhut, R.; Gabius, H.J.; Cramer, F.
Phenylalanyl-tRNA synthetase from chloroplast of a higher plant (Phaseolus vulgaris). Purification and comparison of its structural, functional, and immunological properties with those of the enzymes from the corresponding cytoplasm, the cyanobacterium Anacystis nidulans, and the photosynthetic green sulfur bacterium Chlorobium limicola
J. Biol. Chem.
261
2799-2803
1986
Synechococcus elongatus PCC 7942 = FACHB-805, Chlorobium limicola, Phaseolus vulgaris
Konrad, I.; Rschenthaler, R.
Inhibition of phenylalanine tRNA synthetase from Bacillus subtilis by ochratoxin A
FEBS Lett.
83
341-347
1977
Bacillus subtilis
Fishman, R.; Ankilova, V.; Moor, N.; Safro, M.
Structure at 2.6 A resolution of phenylalanyl-tRNA synthetase complexed with phenylalanyl-adenylate in the presence of manganese
Acta Crystallogr. Sect. D
57
1534-1544
2001
Thermus thermophilus
Beyer, D.; Kroll, H.P.; Endermann, R.; Schiffer, G.; Siegel, S.; Bauser, M.; Pohlmann, J.; Brands, M.; Ziegelbauer, K.; Haebich, D.; Eymann, C.; Brotz-Oesterhelt, H.
New class of bacterial phenylalanyl-tRNA synthetase inhibitors with high potency and broad-spectrum activity
Antimicrob. Agents Chemother.
48
525-532
2004
Escherichia coli, Haemophilus influenzae, Haemophilus influenzae Spain 7, Moraxella catarrhalis, Moraxella catarrhalis 489, Staphylococcus aureus, Staphylococcus aureus 133, Streptococcus pneumoniae, Streptococcus pneumoniae G9A
Rodova, M.; Ankilova, V.; Safro, M.G.
Human phenylalanyl-tRNA synthetase: cloning, characterization of the deduced amino acid sequences in terms of the structural domains and coordinately regulated expression of the alpha and beta subunits in chronic myeloid leukemia cells
Biochem. Biophys. Res. Commun.
255
765-773
1999
Homo sapiens (Q9NSD9), Homo sapiens (Q9Y285), Homo sapiens
Moor, N.; Lavrik, O.; Favre, A.; Safro, M.
Prokaryotic and eukaryotic tetrameric phenylalanyl-tRNA synthetases display conservation of the binding mode of the tRNAPhe CCA end
Biochemistry
42
10697-10708
2003
Homo sapiens
Vasil'eva, I.A.; Ankilova, V.N.; Lavrik, O.I.; Moor, N.A.
Interaction of T. thermophilus phenylalanyl-tRNA synthetase with the 3'-terminal nucleotide of tRNAPhe
Biochemistry
65
1157-1166
2000
Thermus thermophilus
Ivanov, K.A.; Moor, N.A.; Ankilova, V.N.; Lavrik, O.I.
Phenylalanyl-tRNA synthetase interacts with DNA: studies on activity using deoxyribooligonucleotides
Biochemistry (Moscow)
65
436-441
2000
Thermus thermophilus
Stepanov, V.G.; Moor, N.A.; Ankilova, V.N.; Vasil'eva, I.A.; Sukhanova, M.V.; Lavrik, O.I.
A peculiarity of the reaction of tRNA aminoacylation catalyzed by phenylalanyl-tRNA synthetase from the extreme thermophile Thermus thermophilus
Biochim. Biophys. Acta
1386
1-15
1998
Thermus thermophilus, Thermus thermophilus HB8 / ATCC 27634 / DSM 579
Lombardo, B.; Raimo, G.; Bocchini, V.
Molecular and functional properties of an archaeal phenylalanyl-tRNA synthetase from the hyperthermophile Sulfolobus solfataricus
Biochim. Biophys. Acta
1596
246-252
2002
Saccharolobus solfataricus
Das, R.; Vothknecht, U.C.
Phenylalanyl-tRNA synthetase from the archaeon Methanobacterium thermoautotrophicum is an (alphabeta)2 heterotetrameric protein
Biochimie
81
1037-1039
1999
Methanobacterium thermoautotrophicus
Page, W.J.; Mehrotra, M.; Vande Woestyne, M.; Tindale, A.E.; Kujat Choy, S.L.; Macyk, A.S.; Leskiw, B.K.
Iron-regulated phenylalanyl-tRNA synthetase activity in Azotobacter vinelandii
FEMS Microbiol. Lett.
218
15-21
2003
Azotobacter vinelandii (Q8RPZ8), Azotobacter vinelandii
Datta, D.; Wang, P.; Carrico, I.S.; Mayo, S.L.; Tirrell, D.A.
A designed phenylalanyl-tRNA synthetase variant allows efficient in vivo incorporation of aryl ketone functionality into proteins
J. Am. Chem. Soc.
124
5652-5653
2002
Escherichia coli
Shiraki, K.; Tsuji, M.; Hashimoto, Y.; Fujimoto, K.; Fujiwara, S.; Takagi, M.; Imanaka, T.
Genetic, enzymatic, and structural analyses of phenylalanyl-tRNA synthetase from Thermococcus kodakaraensis KOD1
J. Biochem.
134
567-574
2003
Thermococcus kodakarensis (Q76KA8 and Q76KA8)
Lechler, A.; Kreutzer, R.
The phenylalanyl-tRNA synthetase specifically binds DNA
J. Mol. Biol.
278
897-901
1998
Thermus thermophilus (Q5SGX2 and Q5SGX1), Thermus thermophilus
Reshetnikova, L.; Moor, N.; Lavrik, O.; Vassylyev, D.G.
Crystal structures of phenylalanyl-tRNA synthetase complexed with phenylalanine and a phenylalanyl-adenylate analogue
J. Mol. Biol.
287
555-568
1999
Thermus thermophilus
Bullard, J.M.; Cai, Y.C.; Demeler, B.; Spremulli, L.L.
Expression and characterization of a human mitochondrial phenylalanyl-tRNA synthetase
J. Mol. Biol.
288
567-577
1999
Homo sapiens (O95363), Homo sapiens
Kekenes-Huskey, P.M.; Vaidehi, N.; Floriano, W.B.; Goddard, W.A.
Fidelity of Phenylalanyl-tRNA Synthetase in Binding the Natural Amino Acids
J. Phys. Chem. B
107
11549-11557
2003
Thermus thermophilus
-
Savopoulos, J.W.; Hibbs, M.; Jones, E.J.; Mensah, L.; Richardson, C.; Fosberry, A.; Downes, R.; Fox, S.G.; Brown, J.R.; Jenkins, O.
Identification, cloning, and expression of a functional phenylalanyl-tRNA synthetase (pheRS) from Staphylococcus aureus
Protein Expr. Purif.
21
470-484
2001
Staphylococcus aureus
Moor, N.; Linshiz, G.; Safro, M.
Cloning and expression of human phenylalanyl-tRNA synthetase in Escherichia coli: comparative study of purified recombinant enzymes
Protein Expr. Purif.
24
260-267
2002
Homo sapiens
Vasil'eva, I.A.; Favre, A.; Lavrik, O.I.; Moor, N.A.
Effect of nucleotide replacement in tRNAPhe on positioning of the acceptor end in the complex with phenylalanine-tRNA synthetase
Biochemistry
69
154-163
2004
Thermus thermophilus
Yu, X.Y.; Finn, J.; Hill, J.M.; Wang, Z.G.; Keith, D.; Silverman, J.; Oliver, N.
A series of spirocyclic analogues as potent inhibitors of bacterial phenylalanyl-tRNA synthetase
Bioorg. Med. Chem. Lett.
14
1339-1342
2004
Enterococcus faecalis, Staphylococcus aureus
Yu, X.Y.; Finn, J.; Hill, J.M.; Wang, Z.G.; Keith, D.; Silverman, J.; OLiver, N.
A series of heterocyclic inhibitors of phenylalanyl-tRNA synthetases with antibacterial activity
Bioorg. Med. Chem. Lett.
14
1343-1346
2004
Enterococcus faecalis
Jarvest, R.L.; Erskine, S.G.; et.al.
Discovery and optimisation of potent, selective, ethanolamine inhibitors of bacterial phenylalanyl tRNA synthetase
Bioorg. Med. Chem. Lett.
15
2305-2309
2005
Staphylococcus aureus
Pohlmann, J.
Phenylalanyl-tRNA synthetase as a target for potential new antibacterial agents
Drugs Future
29
243-251
2004
Streptococcus pneumoniae, Escherichia coli, Enterococcus faecalis, Haemophilus influenzae, Staphylococcus aureus
-
Roy, H.; Ling, J.; Irnov, M.; Ibba, M.
Post-transfer editing in vitro and in vivo by the beta subunit of phenylalanyl-tRNA synthetase
EMBO J.
23
4639-4648
2004
Escherichia coli
Bentin, T.; Hamzavi, R.; Salomonsson, J.; Roy, H.; Ibba, M.; Nielsen, P.E.
Photoreactive bicyclic amino acids as substrates for mutant Escherichia coli coli phenylalanyl-tRNA synthetase
J. Biol. Chem.
279
19839-19845
2004
Escherichia coli
Roy, H.; Ling, J.; Alfonzo, J.; Ibba, M.
Loss of editing activity during the evolution of mitochondrial phenylalanyl-tRNA synthetase
J. Biol. Chem.
280
38186-18192
2005
Saccharomyces cerevisiae
Kotik-Kogan, O.; Moor, N.; Tworowski, D.; Safro, M.
Structural basis for discrimination of L-phenylalanine from L-tyrosine by phenylalanyl-tRNA synthetase
Structure
13
1799-1807
2005
Thermus thermophilus
Levin, I.; Kessler, N.; Moor, N.; Klipcan, L.; Koc, E.; Templeton, P.; Spremulli, L.; Safro, M.
Purification, crystallization and preliminary X-ray characterization of a human mitochondrial phenylalanyl-tRNA synthetase
Acta Crystallogr. Sect. F
63
761-764
2007
Homo sapiens
Moor, N.; Kotik-Kogan, O.; Tworowski, D.; Sukhanova, M.; Safro, M.
The crystal structure of the ternary complex of phenylalanyl-tRNA synthetase with tRNAPhe and a phenylalanyl-adenylate analogue reveals a conformational switch of the CCA end
Biochemistry
45
10572-10583
2006
Thermus thermophilus
Roy, H.; Ibba, M.
Phenylalanyl-tRNA synthetase contains a dispensable RNA-binding domain that contributes to the editing of noncognate aminoacyl-tRNA
Biochemistry
45
9156-9162
2006
Escherichia coli, Escherichia coli NP37
Kodama, K.; Fukuzawa, S.; Sakamoto, K.; Nakayama, H.; Kigawa, T.; Yabuki, T.; Matsuda, N.; Shirouzu, M.; Takio, K.; Tachibana, K.; Yokoyama, S.
A new protein engineering approach combining chemistry and biology, part I; site-specific incorporation of 4-iodo-L-phenylalanine in vitro by using misacylated suppressor tRNAPhe
Chembiochem
7
1577-1581
2006
Escherichia coli, Escherichia coli NP37
Sasaki, H.M.; Sekine, S.; Sengoku, T.; Fukunaga, R.; Hattori, M.; Utsunomiya, Y.; Kuroishi, C.; Kuramitsu, S.; Shirouzu, M.; Yokoyama, S.
Structural and mutational studies of the amino acid-editing domain from archaeal/eukaryal phenylalanyl-tRNA synthetase
Proc. Natl. Acad. Sci. USA
103
14744-14749
2006
Pyrococcus horikoshii (O73984), Pyrococcus horikoshii
Ling, J.; Yadavalli, S.S.; Ibba, M.
Phenylalanyl-tRNA synthetase editing defects result in efficient mistranslation of phenylalanine codons as tyrosine
RNA
13
1881-1886
2007
Escherichia coli
Barrett, A.R.; Kang, Y.; Inamasu, K.S.; Son, M.S.; Vukovich, J.M.; Hoang, T.T.
Genetic tools for allelic replacement in Burkholderia species
Appl. Environ. Microbiol.
74
4498-4508
2008
Burkholderia pseudomallei
Targoff, I.N.
Autoantibodies and their significance in myositis
Curr. Rheumatol. Rep.
10
333-340
2008
Homo sapiens
Jakava-Viljanen, M.; Murros, A.; Palva, A.; Bjoerkroth, K.J.
Lactobacillus sobrius Konstantinov et al. 2006 is a later synonym of Lactobacillus amylovorus Nakamura 1981
Int. J. Syst. Evol. Microbiol.
58
910-913
2008
Lactobacillus amylovorus
Evdokimov, A.G.; Mekel, M.; Hutchings, K.; Narasimhan, L.; Holler, T.; McGrath, T.; Beattie, B.; Fauman, E.; Yan, C.; Heaslet, H.; Walter, R.; Finzel, B.; Ohren, J.; McConnell, P.; Braden, T.; Sun, F.; Spessard, C.; Banotai, C.; Al-Kassim, L.; Ma, W.; Wengender, P.; Kole, D.; Garceau, N.; Toogood, P.; Liu, J.
Rational protein engineering in action: The first crystal structure of a phenylalanine tRNA synthetase from Staphylococcus haemolyticus
J. Struct. Biol.
162
152-169
2008
Staphylococcus haemolyticus
Oki, K.; Sakamoto, K.; Kobayashi, T.; Sasaki, H.M.; Yokoyama, S.
Transplantation of a tyrosine editing domain into a tyrosyl-tRNA synthetase variant enhances its specificity for a tyrosine analog
Proc. Natl. Acad. Sci. USA
105
13298-13303
2008
Escherichia coli, Pyrococcus horikoshii, Thermus thermophilus
Klipcan, L.; Levin, I.; Kessler, N.; Moor, N.; Finarov, I.; Safro, M.
The tRNA-induced conformational activation of human mitochondrial phenylalanyl-tRNA synthetase
Structure
16
1095-1104
2008
Homo sapiens
Finarov, I.; Moor, N.; Kessler, N.; Safro, M.
Crystallization and X-ray analysis of human cytoplasmic phenylalanyl-tRNA synthetase
Acta Crystallogr. Sect. F
65
93-97
2009
Homo sapiens (O95363), Homo sapiens
Vasileva, I.A.; Semenova, E.A.; Moor, N.A.
Interaction of human phenylalanyl-tRNA synthetase with specific tRNA according to thiophosphate footprinting
Biochemistry (Moscow)
74
175-185
2009
Homo sapiens
Montgomery, J.I.; Toogood, P.L.; Hutchings, K.M.; Liu, J.; Narasimhan, L.; Braden, T.; Dermyer, M.R.; Kulynych, A.D.; Smith, Y.D.; Warmus, J.S.; Taylor, C.
Discovery and SAR of benzyl phenyl ethers as inhibitors of bacterial phenylalanyl-tRNA synthetase
Bioorg. Med. Chem. Lett.
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Streptococcus pneumoniae, Haemophilus influenzae
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Homo sapiens (O95363), Homo sapiens
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Cell-specific differences in the requirements for translation quality control
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Saccharomyces cerevisiae, Escherichia coli, Homo sapiens
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Structure of human cytosolic phenylalanyl-tRNA synthetase: evidence for kingdom-specific design of the active sites and tRNA binding patterns
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Homo sapiens (Q9NSD9), Homo sapiens (Q9Y285), Homo sapiens
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Bombyx mori
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Banerjee, R.; Reynolds, N.M.; Yadavalli, S.S.; Rice, C.; Roy, H.; Banerjee, P.; Alexander, R.W.; Ibba, M.
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Escherichia coli (P08312), Escherichia coli
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Mutation of the human mitochondrial phenylalanine-tRNA synthetase causes infantile-onset epilepsy and cytochrome c oxidase deficiency
Biochim. Biophys. Acta
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Homo sapiens
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Bacterial and eukaryotic phenylalanyl-tRNA synthetases catalyze misaminoacylation of tRNAPhe with 3,4-dihydroxy-L-phenylalanine
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Thermus thermophilus, Homo sapiens, Homo sapiens (O95363)
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Determination of phenylalanine tRNA recognition sites by phenylalanyl-tRNA synthetase from hyperthermophilic archaeon, Aeropyrum pernix K1
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Aeropyrum pernix (Q9Y9I6 and Q9Y9I3), Aeropyrum pernix, Aeropyrum pernix DSM 11879 (Q9Y9I6 and Q9Y9I3)
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Saccharomyces cerevisiae
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Molecular polygamy The promiscuity of L-phenylalanyl-tRNA-synthetase triggers misincorporation of meta- and ortho-tyrosine in monoclonal antibodies expressed by Chinese hamster ovary cells
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Cricetulus griseus
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Translation system engineering in Escherichia coli enhances non-canonical amino acid incorporation into proteins
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High throughput screen identifies natural product inhibitor of phenylalanyl-tRNA synthetase from Pseudomonas aeruginosa and Streptococcus pneumoniae
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Escherichia coli, Pseudomonas aeruginosa, Pseudomonas aeruginosa PAO01
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Saccharomyces cerevisiae
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Inhibitory effects on silk fibroin production by the expression of phenylalanyl-tRNA synthetase mutants in posterior silk glands of Bombyx mori
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Bombyx mori
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Chimeric human mitochondrial PheRS exhibits editing activity to discriminate nonprotein amino acids
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Homo sapiens (O95363), Homo sapiens
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