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Information on EC 5.6.1.1 - microtubule-severing ATPase

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IUBMB Comments
Another member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome.
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
n
+
n
+
a microtubule
=
n
+
n
+
(n+1)
alpha/beta tubulin heterodimers
Synonyms
spastin, katanin, scinderin, mei-1, kinesin spindle protein, adseverin, katanin p60, microtubule-severing protein, microtubule-stimulated atpase, p60-katanin, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers
show the reaction diagram
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