Information on EC 5.6.1.1 - microtubule-severing ATPase

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EC Tree
IUBMB Comments
A member of the AAA-ATPase family, active in splitting microtubules into tubulin dimers in the centrosome.
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria, Archaea
Synonyms
spastin, katanin, scinderin, kinesin spindle protein, mei-1, adseverin, katanin p60, microtubule-severing protein, microtubule-stimulated atpase, p60-katanin, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
n ATP + n H2O + a microtubule = n ADP + n phosphate + (n+1) alpha/beta tubulin heterodimers
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