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Information on EC 5.5.1.8 - (+)-bornyl diphosphate synthase

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EC Tree
IUBMB Comments
Requires Mg2+. The enzyme from Salvia officinalis (sage) can also use (3R)-linalyl diphosphate or more slowly neryl diphosphate in vitro . The reaction proceeds via isomeration of geranyl diphosphate to (3R)-linalyl diphosphate. The oxygen and phosphorus originally linked to C-1 of geranyl diphosphate end up linked to C-2 of (+)-bornyl diphosphate . cf. EC 5.5.1.22 [(-)-bornyl diphosphate synthase].
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
bornyl diphosphate synthase, (+)-bornyl diphosphate synthase, (di)terpene synthase, geranyl pyrophosphate:(+)-bornyl pyrophosphate cyclase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
geranyl diphosphate = (+)-bornyl diphosphate
show the reaction diagram
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