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Disease on EC 5.4.99.5 - chorismate mutase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma
[CR of All Target Lesions in a Patient with Metastatic Esophageal Cancer and Generalized Weakness Treated with Systemic Chemotherapy after Nutritional Support].
Alzheimer Disease
[Inhibition of neuronal death by promoting degradation of intracellular amyloid beta-protein]
Borna Disease
Borna disease virus P-protein is phosphorylated by protein kinase Cepsilon and casein kinase II.
Communicable Diseases
Crystal structure of chorismate mutase from Burkholderia thailandensis.
Cysts
A chorismate mutase from the soybean cyst nematode Heterodera glycines shows polymorphisms that correlate with virulence.
Alternative splicing: A novel mechanism of regulation identified in the chorismate mutase gene of the potato cyst nematode Globodera rostochiensis.
Characterization of a chorismate mutase from the potato cyst nematode Globodera pallida.
Structural and functional investigation of a secreted chorismate mutase from the plant-parasitic nematode Heterodera schachtii in the context of related enzymes from diverse origins.
Distemper
Comparison of messenger RNAs induced in cells infected with each member of the morbillivirus group.
Spot synthesis of overlapping peptides on paper membrane supports enables the identification of linear monoclonal antibody binding determinants on morbillivirus phosphoproteins.
Esophageal Neoplasms
PSMD4 regulates the malignancy of esophageal cancer cells by suppressing endoplasmic reticulum stress.
Glycogen Storage Disease Type II
Specific induction by glycine of the gene for the P-subunit of glycine decarboxylase from Saccharomyces cerevisiae.
Hepatitis B
Expression of the P-protein of the human hepatitis B virus in a vaccinia virus system and detection of the nucleocapsid-associated P-gene product by radiolabelling at newly introduced phosphorylation sites.
Hyperglycinemia, Nonketotic
Enzymatic diagnosis of nonketotic hyperglycinemia with lymphoblasts.
Glycine cleavage system: reaction mechanism, physiological significance, and hyperglycinemia.
Ketogenic diet in early myoclonic encephalopathy due to non ketotic hyperglycinemia.
Molecular genetic and potential biochemical characteristics of patients with T-protein deficiency as a cause of glycine encephalopathy (NKH).
Nonketotic hyperglycinemia: two patients with primary defects of P-protein and T-protein, respectively, in the glycine cleavage system.
Structural and expression analyses of normal and mutant mRNA encoding glycine decarboxylase: three-base deletion in mRNA causes nonketotic hyperglycinemia.
Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia.
Infections
Antibody response to P-protein in patients with Branhamella catarrhalis infections.
Nuclear Trafficking of the Rabies Virus Interferon Antagonist P-Protein Is Regulated by an Importin-Binding Nuclear Localization Sequence in the C-Terminal Domain.
Plant hormones in defense response of Brassica napus to Sclerotinia sclerotiorum - reassessing the role of salicylic acid in the interaction with a necrotroph.
Insulin Resistance
Dehydroepiandrosterone protects against hepatic glycolipid metabolic disorder and insulin resistance induced by high fat via activation of AMPK-PGC-1?-NRF-1 and IRS1-AKT-GLUT2 signaling pathways.
Leiomyoma
Transcervical microwave ablation in type 2 uterine fibroids via a hysteroscopic approach: analysis of ablation profiles.
Lung Neoplasms
Interaction between epidermal growth factor receptor and interleukin-6 receptor in NSCLC progression.
Sodium Danshensu inhibits the progression of lung cancer by regulating PI3K/Akt signaling pathway.
Lupus Erythematosus, Systemic
Anti-ribosomal P-protein and its role in psychiatric manifestations of systemic lupus erythematosus: myth or reality?
Lymphoma, B-Cell
HIF-?/PKM2 and PI3K-AKT pathways involved in the protection by dexmedetomidine against isoflurane or bupivacaine-induced apoptosis in hippocampal neuronal HT22 cells.
I157172, a novel inhibitor of cystathionine ?-lyase, inhibits growth and migration of breast cancer cells via SIRT1-mediated deacetylation of STAT3.
Malaria
Plasmodium berghei glycine cleavage system T-protein is non-essential for parasite survival in vertebrate and invertebrate hosts.
Melanoma
Unrevealing the role of P-protein on melanosome biology and structure, using siRNA-mediated down regulation of OCA2.
Neoplasm Metastasis
[A Case of Neuroendocrine Carcinoma Treated with Salvage Surgery after Systemic Chemotherapy].
Neoplasms
Advanced gastric neuroendocrine carcinoma with an adenocarcinoma component.
Synergistic Activation upon MET and ALK Coamplification Sustains Targeted Therapy in Sarcomatoid Carcinoma, a Deadly Subtype of Lung Cancer.
[A Case of Neuroendocrine Carcinoma Treated with Salvage Surgery after Systemic Chemotherapy].
[A case of primary small intestinal cancer accompanied by virchow lymph node metastasis undergoing TS-1 treatment]
Ovarian Neoplasms
Effect of MicroRNA-210 on the Growth of Ovarian Cancer Cells and the Efficacy of Radiotherapy.
Pneumonia
Antibody response to P-protein in patients with Branhamella catarrhalis infections.
Prostatic Neoplasms
Gold-chrysophanol nanoparticles suppress human prostate cancer progression through inactivating AKT expression and inducing apoptosis and ROS generation in vitro and in vivo.
Pulmonary Atelectasis
Arnold-Chiari Malformation and Scoliosis: A Chronic Lung Collapse Mimicking Sepsis.
Rabies
Dual modes of rabies P-protein association with microtubules: a novel strategy to suppress the antiviral response.
Dynein light chain association sequences can facilitate nuclear protein import.
Interaction of Rabies Virus P-Protein With STAT Proteins is Critical to Lethal Rabies Disease.
Nuclear Trafficking of the Rabies Virus Interferon Antagonist P-Protein Is Regulated by an Importin-Binding Nuclear Localization Sequence in the C-Terminal Domain.
Nucleocytoplasmic distribution of rabies virus p-protein is regulated by phosphorylation adjacent to C-terminal nuclear import and export signals.
Rectocele
Rectoanal inhibition and rectocele: physiology versus categorization.
Respiratory Tract Infections
Antibody response to P-protein in patients with Branhamella catarrhalis infections.
Scoliosis
Arnold-Chiari Malformation and Scoliosis: A Chronic Lung Collapse Mimicking Sepsis.
Tuberculosis
1.6 A crystal structure of the secreted chorismate mutase from Mycobacterium tuberculosis: novel fold topology revealed.
A comparative biochemical and structural analysis of the intracellular chorismate mutase (Rv0948c) from Mycobacterium tuberculosis H(37)R(v) and the secreted chorismate mutase (y2828) from Yersinia pestis.
A novel noncovalent complex of chorismate mutase and DAHP synthase from Mycobacterium tuberculosis: protein purification, crystallization and X-ray diffraction analysis.
A Pd-mediated new strategy to functionalized 2-aminochromenes: their in vitro evaluation as potential anti tuberculosis agents.
AlCl(3) mediated unexpected migration of sulfonyl groups: regioselective synthesis of 7-sulfonyl indoles of potential pharmacological interest.
Biochemical and structural characterization of the secreted chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv: an *AroQ enzyme not regulated by the aromatic amino acids.
Characterization of the secreted chorismate mutase from the pathogen Mycobacterium tuberculosis.
Crystallization and preliminary X-ray crystallographic studies of Mycobacterium tuberculosis chorismate mutase.
Diagnostic Potential of IgG and IgA Responses to Mycobacterium tuberculosis Antigens for Discrimination among Active Tuberculosis, Latent Tuberculosis Infection, and Non-Infected Individuals.
Discovery and Structure Optimization of a Series of Isatin Derivatives as Mycobacterium tuberculosis Chorismate Mutase Inhibitors.
Evolving the naturally compromised chorismate mutase from Mycobacterium tuberculosis to top performance.
Functional mapping of protein-protein interactions in an enzyme complex by directed evolution.
Identification and structure-activity relationship study of carvacrol derivatives as Mycobacterium tuberculosis chorismate mutase inhibitors.
Interaction between DAHP synthase and chorismate mutase endows new regulation on DAHP synthase activity in Corynebacterium glutamicum.
Ligand based virtual screening and biological evaluation of inhibitors of chorismate mutase (Rv1885c) from Mycobacterium tuberculosis H37Rv.
Molecular dynamics simulation of the last step of a catalytic cycle: Product release from the active site of the enzyme chorismate mutase from Mycobacterium tuberculosis.
Mycobacterium tuberculosis chorismate mutase: A potential target for TB.
pheA (Rv3838c) of Mycobacterium tuberculosis encodes an allosterically regulated monofunctional prephenate dehydratase that requires both catalytic and regulatory domains for optimum activity.
Preliminary X-ray crystallographic analysis of the secreted chorismate mutase from Mycobacterium tuberculosis: a tricky crystallization problem solved.
Purification and characterization of a functionally active Mycobacterium tuberculosis prephenate dehydrogenase.
Purified recombinant hypothetical protein coded by open reading frame Rv1885c of Mycobacterium tuberculosis exhibits a monofunctional AroQ class of periplasmic chorismate mutase activity.
Remote Control by Inter-Enzyme Allostery: A Novel Paradigm for Regulation of the Shikimate Pathway.
Structure and function of a complex between chorismate mutase and DAHP synthase: efficiency boost for the junior partner.
The 2.15 A crystal structure of Mycobacterium tuberculosis chorismate mutase reveals an unexpected gene duplication and suggests a role in host-pathogen interactions.
Understanding the different activities of highly promiscuous MbtI by computational methods.
When inhibitors do not inhibit: critical evaluation of rational drug design targeting chorismate mutase from Mycobacterium tuberculosis.
Vaccinia
Expression of the P-protein of the human hepatitis B virus in a vaccinia virus system and detection of the nucleocapsid-associated P-gene product by radiolabelling at newly introduced phosphorylation sites.