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Information on EC 5.4.99.25 - tRNA pseudouridine55 synthase

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EC Tree
     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.25 tRNA pseudouridine55 synthase
IUBMB Comments
Pseudouridine synthase TruB from Escherichia coli specifically modifies uridine55 in tRNA molecules . The bifunctional archaeal enzyme also catalyses the pseudouridylation of uridine54 . It is not known whether the enzyme from Escherichia coli can also act on position 54 in vitro, since this position is occupied in Escherichia coli tRNAs by thymine.
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Reaction Schemes
tRNA uridine55
=
tRNA pseudouridine55
Synonyms
pus10, acbf5, pseudouridine 55 synthase, pseudouridine synthase trub, trna pseudouridine synthase, psi55s, ynl292w, trna:pseudouridine-55 synthase, trna:psi55-synthase, rna pseudouridine synthase trub, more
REACTION
REACTION DIAGRAM
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ORGANISM
UNIPROT
LITERATURE
tRNA uridine55 = tRNA pseudouridine55
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