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Information on EC 5.4.99.12 - tRNA pseudouridine38-40 synthase

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EC Tree
     5 Isomerases
         5.4 Intramolecular transferases
             5.4.99 Transferring other groups
                5.4.99.12 tRNA pseudouridine38-40 synthase
IUBMB Comments
The uridylate residues at positions 38, 39 and 40 of nearly all tRNAs are isomerized to pseudouridine. TruA specifically modifies uridines at positions 38, 39, and/or 40 in the anticodon stem loop of tRNAs with highly divergent sequences and structures .
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Word Map
The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Reaction Schemes
tRNA uridine38-40
=
tRNA pseudouridine38-40
Synonyms
trna pseudouridine synthase i, mpus3p, pus3p, deg1p, pseudouridine synthase 3, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
tRNA uridine38-40 = tRNA pseudouridine38-40
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