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Information on EC 5.3.99.12 - lachrymatory-factor synthase

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EC Tree
IUBMB Comments
The enzyme is responsible for production of the irritating lachrymatory factor that is released by onions and related species when they are chopped. It acts of the product of EC 4.4.1.4, alliin lyase. The enzyme from Allium cepa (onion) acts on (E)-prop-1-en-1-SO-peroxol and produces (Z)-propanethial oxide, while the enzyme from Allium siculum (honey garlic) acts on (E)-but-1-en-1-SO-peroxol and produces (Z)-butanethial oxide.
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Word Map
The enzyme appears in viruses and cellular organisms
Synonyms
lachrymatory factor synthase, lachrymatory-factor synthase, lf synthase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(E)-alk-1-en-1-SO-peroxol = (Z)-alkanethial oxide
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PATHWAY SOURCE
PATHWAYS
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