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(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate
linoleic acid = (10E,12Z)-octadeca-10,12-dienoic acid
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(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate
double bond isomerization
(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate
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(6Z,9Z,12Z)-octadecatrienoic acid
(6Z,10E,12Z)-octadecatrienoic acid
linolenic acid
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?
(9Z,12Z)-octadecadienoic acid
(10E,12Z)-octadecadienoic acid
9-cis,12-cis-linoleic acid
10-trans,12-cis-linoleic acid
linoleic acid
(10E,12Z)-octadeca-10,12-dienoic acid
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?
(9Z,12Z)-octadecadienoic acid
(10E,12Z)-octadecadienoic acid
linoleic acid
conjugated linoleic acid, double bond isomerization
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?
(9Z,12Z)-octadecadienoic acid
(10E,12Z)-octadecadienoic acid
linoleic acid
conjugated linoleic acid, double bound isomerization
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?
9-cis,12-cis-linoleic acid
10-trans,12-cis-linoleic acid
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?
9-cis,12-cis-linoleic acid
10-trans,12-cis-linoleic acid
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the produced conjugated linoleic acid has anti-carcinogenic and anti-atherosclerosis activity, and modulatory effects on the immune system and lipid metabolism, produced by transgenic Oryza sativa rice grains also as trans-10, cis-12 conjugated linoleic acid methyl ester, overview
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?
9-cis,12-cis-linoleic acid
10-trans,12-cis-linoleic acid
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the product, produced by recombinant Lactococcus lactis and Escherichia coli strains, shows anti-proliferative activities in the human SW480 colon cancer cell line, overview
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?
9-cis,12-cis-linoleic acid
10-trans,12-cis-linoleic acid
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?
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9-cis,12-cis-linoleic acid
10-trans,12-cis-linoleic acid
linoleic acid
(10E,12Z)-octadeca-10,12-dienoic acid
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?
9-cis,12-cis-linoleic acid
10-trans,12-cis-linoleic acid
-
-
the produced conjugated linoleic acid has anti-carcinogenic and anti-atherosclerosis activity, and modulatory effects on the immune system and lipid metabolism, produced by transgenic Oryza sativa rice grains also as trans-10, cis-12 conjugated linoleic acid methyl ester, overview
-
?
9-cis,12-cis-linoleic acid
10-trans,12-cis-linoleic acid
-
-
the product, produced by recombinant Lactococcus lactis and Escherichia coli strains, shows anti-proliferative activities in the human SW480 colon cancer cell line, overview
-
?
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DNA and amino acid sequence determination and analysis, functional overexpression in Lactococcus lactis strain NZ9800 and Escherichia coli strain DH5alpha, which produce 10-trans,12-cis-linoleic acid, overview
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expressed in Yarrowia lipolytica
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expression in Escherichia coli, in Saccharomyces cerevisiae and in transgenic tabacco cells
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expression in transgenic Oryza sativa plants by Agrobacterium tumefaciens-mediated transformation under the control of seed-specific promoters from the oleosin and globulin genes, analysis of oil composition in transgenic seeds, overview
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overexpression in Escherichia coli as a GST-fusion protein
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Hornung, E.; Krueger, C.; Pernstich, C.; Gipmans, M.; Porzel, A.; Feussner, I.
Production of (10E,12Z)-conjugated linoleic acid in yeast and tobacco seeds
Biochim. Biophys. Acta
1738
105-114
2005
Cutibacterium acnes
brenda
Liavonchanka, A.; Hornung, E.; Feussner, I.; Rudolph, M.
In-house SIRAS phasing of the polyunsaturated fatty-acid isomerase from Propionibacterium acnes
Acta Crystallogr. Sect. F
62
153-156
2006
Cutibacterium acnes (Q6A8X5)
brenda
Liavonchanka, A.; Hornung, E.; Feussner, I.; Rudolph, M.G.
Structure and mechanism of the Propionibacterium acnes polyunsaturated fatty acid isomerase
Proc. Natl. Acad. Sci. USA
103
2576-2581
2006
Cutibacterium acnes (Q6A8X5)
brenda
Rosberg-Cody, E.; Johnson, M.C.; Fitzgerald, G.F.; Ross, P.R.; Stanton, C.
Heterologous expression of linoleic acid isomerase from Propionibacterium acnes and anti-proliferative activity of recombinant trans-10, cis-12 conjugated linoleic acid
Microbiology
153
2483-2490
2007
Cutibacterium acnes
brenda
Kohno-Murase, J.; Iwabuchi, M.; Endo-Kasahara, S.; Sugita, K.; Ebinuma, H.; Imamura, J.
Production of trans-10, cis-12 conjugated linoleic acid in rice
Transgenic Res.
15
95-100
2006
Cutibacterium acnes
brenda
Liavonchanka, A.; Feussner, I.
Biochemistry of PUFA double bond isomerases producing conjugated linoleic acid
ChemBioChem
9
1867-1872
2008
Cutibacterium acnes
brenda
Rosberg-Cody, E.; Stanton, C.; OMahony, L.; Wall, R.; Shanahan, F.; Quigley, E.M.; Fitzgerald, G.F.; Ross, R.P.
Recombinant lactobacilli expressing linoleic acid isomerase can modulate the fatty acid composition of host adipose tissue in mice
Microbiology
157
609-615
2011
Cutibacterium acnes, Cutibacterium acnes NFBC 338 (Lb338)
brenda
Zhang, B.; Rong, C.; Chen, H.; Song, Y.; Zhang, H.; Chen, W.
De novo synthesis of trans-10, cis-12 conjugated linoleic acid in oleaginous yeast Yarrowia lipolytica
Microb. Cell Fact.
11
51
2012
Cutibacterium acnes
brenda
Zhang, B.; Chen, H.; Li, M.; Gu, Z.; Song, Y.; Ratledge, C.; Chen, Y.Q.; Zhang, H.; Chen, W.
Genetic engineering of Yarrowia lipolytica for enhanced production of trans-10, cis-12 conjugated linoleic acid
Microb. Cell Fact.
12
70
2013
Cutibacterium acnes
brenda
5.3.3.B2 linoleate (10E,12Z)-isomerase
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