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Information on EC 5.3.1.28 - D-sedoheptulose 7-phosphate isomerase

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IUBMB Comments
In Gram-negative bacteria the enzyme is involved in biosynthesis of ADP-L-glycero-beta-D-manno-heptose, which is utilized for assembly of the lipopolysaccharide inner core. In Gram-positive bacteria the enzyme is involved in biosynthesis of GDP-D-glycero-alpha-D-manno-heptose, which is required for assembly of S-layer glycoprotein.
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The enzyme appears in viruses and cellular organisms
Synonyms
phosphoheptose isomerase, sedoheptulose-7-phosphate isomerase, sedoheptulose 7-phosphate isomerase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
D-sedoheptulose 7-phosphate = D-glycero-D-manno-heptose 7-phosphate
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