Reference on EC 5.1.99.1 - methylmalonyl-CoA epimerase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Stabler, S.P.; Marcell, P.D.; Allen, R.H.
Isolation and characterization of DL-methylmalonyl-coenzyme A racemase from rat liver
Arch. Biochem. Biophys.
241
252-264
1985
Rattus norvegicus
Fuller, J.Q.; Leadlay, P.F.
Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii
Biochem. J.
213
643-650
1983
Homo sapiens, Propionibacterium freudenreichii subsp. shermanii
Leadlay, P.F.; Fuller, J.Q.
Proton transfer in methylmalonyl-CoA epimerase from Propionibacterium shermanii
Biochem. J.
213
635-642
1983
Propionibacterium freudenreichii subsp. shermanii
Leadlay, P.F.
Purification and characterization of methylmalonyl-CoA epimerase from Propionibacterium shermanii
Biochem. J.
197
413-419
1981
Propionibacterium freudenreichii subsp. shermanii
Allen, S.H.G.; Kellermeyer, R.W.; Wood, H.G.
Methylmalonyl-CoA racemase from Propionibacterium shermanii
Methods Enzymol.
13
194-198
1969
Propionibacterium freudenreichii subsp. shermanii
-
Mazumder, R.
Methylmalonyl-CoA racemase from sheep liver
Methods Enzymol.
13
190-194
1969
Ovis aries
-
Overath, P.; Kellerman, G.M.; Lynen, F.; Fritz, H.P.; Keller, H.J.
Zum Mechanismus der Umlagerung von Methylmalonyl-CoA in Succinyl-CoA. II. Versuche zur Wirkungsweise von Methylmalonyl-CoA Isomerase und Methylmalonyl-CoA-Racemase
Biochem. Z.
335
500-518
1962
Propionibacterium freudenreichii subsp. shermanii
-
Mazumder, R.; Sasakawa, T.; Kaziro, Y.; Ochoa, S.
Metabolism of propionic acid in animal tissues
J. Biol. Chem.
237
3065-3068
1962
Ovis aries
Stabler, S.P.; Allen, R.H.
DL-Methylmalonyl-CoA racemase from rat liver
Methods Enzymol.
166
400-406
1988
Rattus norvegicus
McCarthy, A.A.; Baker, H.M.; Shewry, S.C.; Kagawa, T.F.; Saafi, E.; Patchett, M.L.; Baker, E.N.
Expression, crystallization and preliminary characterization of methylmalonyl coenzyme A epimerase from Propionibacterium shermanii
Acta Crystallogr. Sect. D
57
706-708
2001
Propionibacterium freudenreichii subsp. shermanii
Bobik, T.A.; Rasche, M.E.
Purification and partial characterization of the Pyrococcus horikoshii methylmalonyl-CoA epimerase
Appl. Microbiol. Biotechnol.
63
682-685
2004
Pyrococcus horikoshii
McCarthy, A.A.; Baker, H.M.; Shewry, S.C.; Patchett, M.L.; Baker, E.N.
Crystal structure of methylmalonyl-coenzyme A epimerase from P. shermanii: a novel enzymatic function on an ancient metal binding scaffold
Structure
9
637-646
2001
Propionibacterium freudenreichii subsp. shermanii
Khnl, J.; Bobik, T.; Procter, J.B.; Burmeister, C.; Hoppner, J.; Wilde, I.; Luersen, K.; Torda, A.E.; Walter, R.D.; Liebau, E.
Functional analysis of the methylmalonyl-CoA epimerase from Caenorhabditis elegans
FEBS J.
272
1465-1477
2005
Caenorhabditis elegans
Gross, F.; Ring, M.W.; Perlova, O.; Fu, J.; Schneider, S.; Gerth, K.; Kuhlmann, S.; Stewart, A.F.; Zhang, Y.; Mueller, R.
Metabolic engineering of Pseudomonas putida for methylmalonyl-CoA biosynthesis to enable complex heterologous secondary metabolite formation
Chem. Biol.
13
1253-1264
2006
Sorangium cellulosum (A1IVX2)
Bikker, H.; Bakker, H.D.; Abeling, N.G.; Poll-The, B.T.; Kleijer, W.J.; Rosenblatt, D.S.; Waterham, H.R.; Wanders, R.J.; Duran, M.
A homozygous nonsense mutation in the methylmalonyl-CoA epimerase gene (MCEE) results in mild methylmalonic aciduria
Hum. Mutat.
27
640-643
2006
Homo sapiens (Q96PE7), Homo sapiens
Dobson, C.M.; Gradinger, A.; Longo, N.; Wu, X.; Leclerc, D.; Lerner-Ellis, J.; Lemieux, M.; Belair, C.; Watkins, D.; Rosenblatt, D.S.; Gravel, R.A.
Homozygous nonsense mutation in the MCEE gene and siRNA suppression of methylmalonyl-CoA epimerase expression: a novel cause of mild methylmalonic aciduria
Mol. Genet. Metab.
88
327-333
2006
Homo sapiens (Q96PE7), Homo sapiens
Chandler, R.J.; Aswani, V.; Tsai, M.S.; Falk, M.; Wehrli, N.; Stabler, S.; Allen, R.; Sedensky, M.; Kazazian, H.H.; Venditti, C.P.
Propionyl-CoA and adenosylcobalamin metabolism in Caenorhabditis elegans: evidence for a role of methylmalonyl-CoA epimerase in intermediary metabolism
Mol. Genet. Metab.
89
64-73
2006
Caenorhabditis elegans
Erb, T.J.; Retey, J.; Fuchs, G.; Alber, B.E.
Ethylmalonyl-CoA mutase from Rhodobacter sphaeroides defines a new subclade of coenzyme B12-dependent acyl-CoA mutases
J. Biol. Chem.
283
32283-32293
2008
Cereibacter sphaeroides (Q3IZP4)
Shi, L.; Gao, P.; Yan, X.; Liang, D.
Crystal structure of a putative methylmalonyl-coenzyme a epimerase from Thermoanaerobacter tengcongensis at 2.0 resolution
Proteins
77
994-999
2009
Caldanaerobacter subterraneus subsp. tengcongensis (Q8RCQ6), Caldanaerobacter subterraneus subsp. tengcongensis
Boghigian, B.; Zhang, H.; Pfeifer, B.
Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions
Biotechnol. Bioeng.
108
1360-1371
2011
Streptomyces coelicolor, Streptomyces coelicolor A3(2)
Han, Y.; Hawkins, A.S.; Adams, M.W.; Kelly, R.M.
Epimerase (Msed_0639) and mutase (Msed_0638 and Msed_2055) convert (S)-methylmalonyl-coenzyme A (CoA) to succinyl-CoA in the Metallosphaera sedula 3-hydroxypropionate/4-hydroxybutyrate cycle
Appl. Environ. Microbiol.
78
6194-6202
2012
Metallosphaera sedula (A4YEG2), Metallosphaera sedula DSM 5348 (A4YEG2)
Yang, S.; Ren, J.; Shang, G.
Construction of an engineered strain of Pseudomonas producing 2S-methylmalonyl-CoA
Chin. J. Antibiot.
36
191-196
2011
Streptomyces coelicolor
-
Hamed, R.B.; Gomez-Castellanos, J.R.; Sean Froese, D.; Krysztofinska, E.; Yue, W.W.; Schofield, C.J.
Use of methylmalonyl-CoA epimerase in enhancing crotonase stereoselectivity
ChemBioChem
17
471-473
2016
Homo sapiens (Q96PE7)
Gonzalez-Garcia, R.; McCubbin, T.; Wille, A.; Plan, M.; Nielsen, L.; Marcellin, E.
Awakening sleeping beauty Production of propionic acid in Escherichia coli through the sbm operon requires the activity of a methylmalonyl-CoA epimerase
Microb. Cell Fact.
16
121
2017
Acidipropionibacterium acidipropionici (K7SKA8), Acidipropionibacterium acidipropionici, Acidipropionibacterium acidipropionici DSM 20272 (K7SKA8)
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