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Information on EC 5.1.3.24 - N-acetylneuraminate epimerase

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EC Tree
     5 Isomerases
         5.1 Racemases and epimerases
             5.1.3 Acting on carbohydrates and derivatives
                5.1.3.24 N-acetylneuraminate epimerase
IUBMB Comments
Sialoglycoconjugates present in vertebrates are linked exclusively by alpha-linkages and are released in alpha form during degradation. This enzyme accelerates maturotation to the beta form (which also occurs as a slow spontaneous reaction), which is necessary for further metabolism by the bacteria.
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The expected taxonomic range for this enzyme is: Escherichia coli
Synonyms
N-acetylneuraminate mutarotase, sialic acid epimerase, YjhT, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
N-acetyl-alpha-neuraminate = N-acetyl-beta-neuraminate
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