Reference on EC 5.1.3.2 - UDP-glucose 4-epimerase
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Arabshahi, A.; Flentke, G.R.; Frey, P.A.
Uridine diphosphate galactose 4-epimerase. pH-Dependence of the reduction of NAD+ by a substrate analog
J. Biol. Chem.
263
2638-2643
1988
Escherichia coli
Mukherji, S.; Bhaduri, A.
UDP-glucose 4-epimerase from Saccharomyces fragilis. Presence of an essential arginine residue at the substrate-binding site of the enzyme
J. Biol. Chem.
261
4519-4524
1986
Saccharomyces fragilis
Thomson, K.S.; Jung, C.; Kauss, H.
UDP-glucose-4-epimerase from Poterioochromonas malhamensis
Phytochemistry
23
979-981
1984
Poterioochromonas malhamensis
-
Dey, P.M.
UDP-galactose 4'-epimerase from Vicia faba seeds
Phytochemistry
23
729-732
1984
Vicia faba
-
Fukasawa, T.; Segawa, T.; Nogi, Y.
Uridine diphosphate glucose-4-epimerase and galactose-1-phosphate uridylyltransferase from Saccharomyces cerevisiae
Methods Enzymol.
89
584-592
1982
Saccharomyces cerevisiae
Bilisics, L.; Karacsonyi, S.; Kubackova, M.
IDP-D-glucose 4-epimerase activity of the tissue culture of white poplars (Populus alba L-var. pyramidalis)
Collect. Czech. Chem. Commun.
47
1530-1536
1982
Populus alba
-
Fukasawa, T.; Obonai, K.; Segawa, T.; Nogi, Y.
The enzymes of the galactose cluster in Saccharomyces cerevisiae. II. Purification and characterization of uridine diphosphoglucose 4-epimerase
J. Biol. Chem.
255
2705-2707
1980
Saccharomyces cerevisiae
Clermont, S.; Percheron, F.
Uridine diphosphogalactose-4 epimerase de fenugrec: essais de purification et quelques proprietes
Phytochemistry
18
1963-1965
1979
Trigonella sp.
-
Ray, M.; Bhaduri, A.
UDPglucose 4-epimerase from Saccharomyces fragilis: asymmetry in allosteric properties leads to unidirectional catalysis
Biochem. Biophys. Res. Commun.
85
242-248
1978
Saccharomyces fragilis
Ray, M.; Kar, K.; Bhaduri, A.
UDP-glucose 4-epimerase from Saccharomyces fragilis. Involvement of sulfhydryl group(s) at the active site
Biochim. Biophys. Acta
526
635-639
1978
Saccharomyces fragilis
Lee, L.J.; Kimura, A.; Tochikura, T.
Purification and properties of UDP-galactose 4-epimerase from Bifidobacterium bifidum
Agric. Biol. Chem.
42
731-737
1978
Bifidobacterium bifidum
-
Geren, C.R.; Geren, L.M.; Ebner, K.E.
Inhibition and inactivation of bovine mammary and liver UDP-galactose-4-epimerase
J. Biol. Chem.
252
2089-2094
1977
Bos taurus
Geren, C.R.; Ebner, K.E.
Purification and characterization of UDP-galactose-4-epimerase from bovine tissues
J. Biol. Chem.
252
2082-2088
1977
Bos taurus
Blackburn, P.; Ferdinand, W.
The concerted inactivation of Escherichia coli uridine diphosphate galactose 4-epimerase by sugar nucleotide together with a free sugar
Biochem. J.
155
225-229
1976
Escherichia coli
Ray, M.; Bhaduri, A.
Uridine-diphosphate-glucose 4-epimerase from Saccharomyces fragilis
Eur. J. Biochem.
70
319-323
1976
Saccharomyces fragilis
Gabrial, O.; Kalckar, H.M.; Darrow, R.A.
UDP-galactose-4-epimerase
ubunit enzymes: biochemistry and function
(Ebner, K. B., ed.)
2
85-135
1975
Bos taurus, Kluyveromyces marxianus, Escherichia coli, Vigna radiata var. radiata, Saccharomyces fragilis, Torulopsis candida
-
Ray, M.; Bhaduri, A.
UDPglucose 4-epimerase from Saccharomyces fragilis: desensitization with heat
Biochem. Biophys. Res. Commun.
67
877-882
1975
Saccharomyces fragilis
Ray, M.; Bhaduri, A.
UDPglucose 4-epimerase from Saccharomyces fragilis. Allosteric kinetics with UDP-glucose as substrate
J. Biol. Chem.
250
4373-4375
1975
Saccharomyces fragilis
Bergren, W.R.; Ng, W.G.; Donnell, G.N.
Uridine diphosphate galactose 4-epimerase in human and other mammalian hemolysates
Biochim. Biophys. Acta
315
464-472
1973
Felis catus, Homo sapiens, Mus musculus
-
Adair, W.L.; Gabriel, O.; Ullrey, D.; Kalckar, H.M.
4-Uloses as intermediates in enzyme-nicotinamide adenine dinucleotide-mediated oxidoreductase mechanisms
J. Biol. Chem.
248
4635-4639
1973
Escherichia coli
Ray, M.; Bhaduri, A.
Two forms of UDPglucose-4-epimerase from mammalian liver
Biochim. Biophys. Acta
302
129-134
1973
Bos taurus, Capra hircus
Spencer, M.; Blackburn, P.; Ferdinand, W.; Blackburn, G.M.
Competitive inhibition and substrate activity of uridine diphosphate 6-deoxygalactose for Escherichia coli uridine diphosphate galactose 4-epimerase
Biochem. J.
131
421-423
1973
Escherichia coli
Wilson, D.B.; Hogness, D.S.
The enzymes of the galactose operon in Escherichia coli. I. Purification and characterization of uridine diphosphogalactose 4-epimerase
J. Biol. Chem.
239
2469-2481
1964
Escherichia coli
Vorgias, C.E.; Lemaire, H.G.; Wilson, K.S.
Overexpression and purification of the galactose operon enzymes from Escherichia coli
Protein Expr. Purif.
2
330-338
1991
Escherichia coli
Bauer, A.J.; Rayment, I.; Frey, P.A.; Holden, H.M.
The isolation, purification, and preliminary crystallographic characterization of UDP-galactose-4-epimerase from Escherichia coli
Proteins Struct. Funct. Genet.
9
135-142
1991
Escherichia coli
Ray, S.; Ali, E.; Bhaduri, A.
Microenvironment at the substrate subsite of the active site of UDPglucose 4-epimerase from Kluyveromyces fragilis using a fluorescent analog of UMP
Indian J. Biochem. Biophys.
29
209-213
1992
Kluyveromyces marxianus
Bhattacharyya, D.
Reversible folding of UDP-galactose-4-epimerase from yeast Kluyveromyces fragilis
Biochemistry
32
9726-9734
1993
Kluyveromyces marxianus
Vanhooke, J.L.; Frey, P.A.
Characterization and activation of naturally occuring abortive complexes of UDP-galactose 4-epimerase from Escherichia coli
J. Biol. Chem.
269
31596-31504
1994
Escherichia coli
-
Skrzypek, M.; Maleszka, R.
A gene homologous to that encoding UDP galactose-4-epimerase is inducible by xylose in the yeast Pachysolen tannophilus
Gene
140
127-129
1994
Pachysolen tannophilus (P40801), Pachysolen tannophilus
De Troch, P.; Keijers, V.; Vanderleyden, J.
Sequence analysis of the Azospirillum brasiliense exoB gene, encoding UDP-glucose 4'-epimerase
Gene
144
143-144
1994
Azospirillum brasilense
Tamada, Y.; Swanson, B.A.; Arabshahi, A.; Frey, P.A.
Preparation and characterization of a bifunctional fusion enzyme composed of UDP-galactose 4-epimerase and galactose-1-P uridylyltransferase
Bioconjug. Chem.
5
660-665
1994
Escherichia coli
Daude, N.; Gallaher, T.K.; Zeschnigk, M.; Starzinski-Powitz, A.; Petry, K.G.; Haworth, I.S.; Reichhardt, J.K.V.
Molecular cloning, characterization, and mapping of a full-length cDNA encoding human UDP-galactose 4'-epimerase
Biochem. Mol. Med.
56
1-7
1995
Homo sapiens
Liu, Y.; Vanhooke, J.L.; Frey, P.A.
UDP-galactose 4-epimerase: NAD+ content and a charge-transfer band associated with the substrate-induced conformational transition
Biochemistry
35
7615-7620
1996
Escherichia coli
Drmann, P.; Benning, C.
Functional expression of uridine 5'-diphospho-glucose 4-epimerase (EC 5.1.3.2) from Arabidopsis thaliana in Saccharomyces cerevisiae and Escherichia coli
Arch. Biochem. Biophys.
327
27-34
1996
Arabidopsis thaliana
Prosselkov, P.V.; Gross, W.; Igamberdiev, A.U.; Scharrenberger, C.
Purification and characterization of UDP-D-galactose 4-epimerase from the red alga Galdieria sulphuraria
Physiol. Plant.
98
753-758
1996
Galdieria sulphuraria
-
Scupham, A.J.; Triplett, E.W.
Isolation and characterization of the UDP-glucose 4'-epimerase-encoding gene, galE, from Brucella abortus 2308
Gene
202
53-59
1997
Brucella abortus
Liu, Y.; Thoden, J.B.; Kim, J.; Berger, E.; Gulick, A.M.; Ruzicka, F.J.; Holden, H.M.; Frey, P.A.
Mechanistic roles of tyrosine 149 and serine 124 in UDP-galactose 4-epimerase from Escherichia coli
Biochemistry
36
10675-10684
1997
Escherichia coli
Nayar, S.; Bhattacharyya, D.
UDP-galactose 4-epimerase from Escherichia coli: existence of a catalytic monomer
FEBS Lett.
409
449-451
1997
Escherichia coli
Dutta, S.; Maiti, N.R.; Bhattacharyya, D.
Reversible folding of UDP-galactose 4-epimerase from Escherichia coli
Eur. J. Biochem.
244
407-413
1997
Escherichia coli
Carmenes, R.S.; Gascon, S.; Moreno, F.
Mechanism of inactivation of UDP-glucose 4-epimerase from Saccharomyces cerevisiae by D-xylose and L-arabinose
Yeast
2
101-108
1986
Saccharomyces cerevisiae
Flentke, G.R.; Frey, P.A.
Reaction of uridine diphosphate galactose 4-epimerase with a suicide inactivator
Biochemistry
29
2430-2436
1990
Escherichia coli
Thoden, J.B.; Gulick, A.M.; Holden, H.M.
Molecular structures of the S124A, S124T, and S124V site-directed mutants of UDP-galactose 4-epimerase from Escherichia coli
Biochemistry
36
10685-10695
1997
Escherichia coli (P09147), Escherichia coli
Thoden, J.B.; Frey, P.A.; Holden, H.M.
High-resolution X-ray structure of UDP-galactose 4-epimerase complexed with UDP-phenol
Protein Sci.
5
2149-2161
1996
Escherichia coli
Thoden, J.B.; Frey, P.A.; Holden, H.M.
Molecular structure of the NADH/UDP-glucose abortive complex of UDP-galactose 4-epimerase from Escherichia coli: implications for the catalytic mechanism
Biochemistry
35
5137-5144
1996
Escherichia coli (P09147), Escherichia coli
Thoden, J.B.; Frey, P.A.; Holden, H.M.
Crystal structures of the oxidized and reduced forms of UDP-galactose 4-epimerase isolated from Escherichia coli
Biochemistry
35
2557-2566
1996
Escherichia coli (P09147), Escherichia coli
Swanson, B.A.; Frey, P.A.
Identification of lysine 153 as a functionally important residue in UDP-galactose 4-epimerase from Escherichia coli
Biochemistry
32
13231-13236
1993
Escherichia coli
Mukherji, S.; Bhaduri, A.
An essential histidine residue for the activity of UDPglucose 4-epimerase from Kluyveromyces fragilis
J. Biol. Chem.
267
11709-11713
1992
Kluyveromyces marxianus
Bauer, A.J.; Rayment, I.; Frey, P.A.; Holden, H.M.
The molecular structure of UDP-galactose 4-epimerase from Escherichia coli determined at 2.5 A resolution
Proteins
12
372-381
1992
Escherichia coli
Poolman, B.; Royer, T.J.; Mainzer, S.E.; Schmidt, B.F.
Carbohydrate utilization in Streptococcus thermophilus: characterization of the genes for aldose 1-epimerase (mutarotase) and UDPglucose 4-epimerase
J. Bacteriol.
172
4037-4047
1990
Streptomyces thermophilus
Oguiza, J.A.; Marcos, A.T.; Malumbres, M.; Martin J.F.
The galE gene encoding the UDP-galactose 4-epimerase of Brevibacterium lactofermentum is coupled transcriptionally to the dmdR gene
Gene
177
103-107
1996
Corynebacterium glutamicum
Barat, B.; Bhattacharyya, D.
UDP-galactose 4-epimerase from Escherichia coli: formation of catalytic site during reversible folding
Arch. Biochem. Biophys.
391
188-196
2001
Escherichia coli
Thoden, J.B.; Wohlers, T.M.; Fridovich-Keil, J.L.; Holden, H.M.
Crystallographic evidence for Tyr 157 functioning as the active site base in human UDP-galactose 4-epimerase
Biochemistry
39
5691-5701
2000
Homo sapiens
Wei, Y.; Lin, J.; Frey, P.A.
13C NMR analysis of electrostatic interactions between NAD+ and active site residues of UDP-galactose 4-epimerase: implications for the activation induced by uridine nucleotides
Biochemistry
40
11279-11287
2001
Escherichia coli (P09147)
Berger, E.; Arabshahi, A.; Wei, Y.; Schilling, J.F.; Frey, P.A.
Acid-base catalysis by UDP-galactose 4-epimerase: correlations of kinetically measured acid dissociation constants with thermodynamic values for tyrosine 149
Biochemistry
40
6699-6705
2001
Escherichia coli
Liu, Y.; Arabshahi, A.; Frey, P.A.
Rate enhancements brought about by uridine nucleotides in the reduction of NAD+ at the active site of UDP-galactose 4-epimerase
Bioorg. Chem.
28
29-37
2000
Escherichia coli
-
Chen, X.; Kowal, P.; Hamad, S.; Fan, H.; Wang, P.G.
Cloning, expression and characterization of a UDP-galactose 4-epimerase from Escherichia coli
Biotechnol. Lett.
21
1131-1135
1999
Escherichia coli
-
Majumdar, S.; Bhattacharjee, H.; Bhattacharyya, D.; Bhaduri, A.
UDP-galactose 4-epimerase from Kluyveromyces fragilis: reconstitution of holoenzyme structure after dissociation with parachloromercuribenzoate
Eur. J. Biochem.
257
427-433
1998
Kluyveromyces marxianus
Brahma, A.; Bhattacharyya, D.
UDP-galactose 4-epimerase from Kluyveromyces fragilis. Evidence for independent mutarotation site
Eur. J. Biochem.
271
58-68
2004
Kluyveromyces marxianus
Majumdar, S.; Ghatak, J.; Mukherji, S.; Bhattacharjee, H.; Bhaduri, A.
UDPgalactose 4-epimerase from Saccharomyces cerevisiae. A bifunctional enzyme with aldose 1-epimerase activity
Eur. J. Biochem.
271
753-759
2004
Saccharomyces cerevisiae
Mozzi, F.; Savoy de Giori, G.; Font de Valdez, G.
UDP-galactose 4-epimerase: a key enzyme in exopolysaccharide formation by Lactobacillus casei CRL 87 in controlled pH batch cultures
J. Appl. Microbiol.
94
175-183
2003
Lacticaseibacillus casei, Lacticaseibacillus casei CL 87
Bhattacharyya, U.; Dhar, G.; Bhaduri, A.
An arginine residue is essential for stretching and binding of the substrate on UDP-glucose-4-epimerase from Escherichia coli. Use of a stacked and quenched uridine nucleotide fluorophore as probe
J. Biol. Chem.
274
14573-14578
1999
Escherichia coli
Thoden, J.B.; Wohlers, T.M.; Fridovich-Keil, J.L.; Holden, H.M.
Human UDP-galactose 4-epimerase. Accommodation of UDP-N-acetylglucosamine within the active site
J. Biol. Chem.
276
15131-15136
2001
Homo sapiens (Q14376), Homo sapiens
Holden, H.M.; Rayment, I.; Thoden, J.B.
Structure and function of enzymes of the Leloir pathway for galactose metabolism
J. Biol. Chem.
278
43885-43888
2003
Escherichia coli, Homo sapiens
Lake, M.R.; Williamson, C.L.; Slocum, R.D.
Molecular cloning and characterization of a UDP-glucose-4-epimerase gene (galE) and its expression in pea tissues
Plant Physiol. Biochem.
36
555-562
1998
Pisum sativum
-
Zhang, Q.; Hrmova, M.; Shirley, N.J.; Lahnstein, J.; Fincher, G.B.
Gene expression patterns and catalytic properties of UDP-D-glucose 4-epimerases from barley (Hordeum vulgare L.)
Biochem. J.
394
115-124
2005
Hordeum vulgare, Hordeum vulgare (Q58IJ6), Hordeum vulgare L.
Nayar, S.; Brahma, A.; Barat, B.; Bhattacharyya, D.
UDP-galactose 4-epimerase from Kluyveromyces fragilis: analysis of its hysteretic behavior during catalysis
Biochemistry
43
10212-10223
2004
Kluyveromyces marxianus
Timson, D.J.
Functional analysis of disease-causing mutations in human UDP-galactose 4-epimerase
FEBS J.
272
6170-6177
2005
Homo sapiens
Santhanagopalan, V.; Coker, C.; Radulovic, S.
Characterization of RP 333, a gene encoding CapD of Rickettsia prowazekii with UDP-glucose 4-epimerase activity
Gene
369
119-125
2005
Rickettsia prowazekii
Frirdich, E.; Whitfield, C.
Characterization of Gla(KP), a UDP-galacturonic acid C4-epimerase from Klebsiella pneumoniae with extended substrate specificity
J. Bacteriol.
187
4104-4115
2005
Klebsiella pneumoniae
Schulz, J.M.; Watson, A.L.; Sanders, R.; Ross, K.L.; Thoden, J.B.; Holden, H.M.; Fridovich-Keil, J.L.
Determinants of function and substrate specificity in human UDP-galactose 4'-epimerase
J. Biol. Chem.
279
32796-32803
2004
Homo sapiens
Schulz, J.M.; Ross, K.L.; Malmstrom, K.; Krieger, M.; Fridovich-Keil, J.L.
Mediators of galactose sensitivity in UDP-galactose 4'-epimerase-impaired mammalian cells
J. Biol. Chem.
280
13493-13502
2005
Escherichia coli, Homo sapiens
Thoden, J.B.; Holden, H.M.
The molecular architecture of galactose mutarotase/UDP-galactose 4-epimerase from Saccharomyces cerevisiae
J. Biol. Chem.
280
21900-21907
2005
Saccharomyces cerevisiae
Bernatchez, S.; Szymanski, C.M.; Ishiyama, N.; Li, J.; Jarrell, H.C.; Lau, P.C.; Berghuis, A.M.; Young, N.M.; Wakarchuk, W.W.
A single bifunctional UDP-GlcNAc/Glc 4-epimerase supports the synthesis of three cell surface glycoconjugates in Campylobacter jejuni
J. Biol. Chem.
280
4792-4802
2005
Campylobacter jejuni
Wubben, M.J.2nd.; Rodermel, S.R.; Baum, T.J.
Mutation of a UDP-glucose-4-epimerase alters nematode susceptibility and ethylene responses in Arabidopsis roots
Plant J.
40
712-724
2004
Arabidopsis thaliana
Oomen, R.J.F.J.; Dao-Thi, B.; Tzitzikas, E.N.; Bakx, E.J.; Schols, H.A.; Visser, R.G.F.; Vincken, J.P.
Overexpression of two different potato UDP-Glc 4-epimerases can increase the galactose content of potato tuber cell walls
Plant Sci.
166
1097-1104
2004
Solanum tuberosum
Alphey, M.S.; Burton, A.; Urbaniak, M.D.; Boons, G.J.; Ferguson, M.A.; Hunter, W.N.
Trypanosoma brucei UDP-galactose-4-epimerase in ternary complex with NAD+ and the substrate analog UDP-4-deoxy-4-fluoro-alpha -D-galactose
Acta Crystallogr. Sect. F
F62
829-834
2006
Trypanosoma brucei
Guo, H.; Yi, W.; Li, L.; Wang, P.G.
Three UDP-hexose 4-epimerases with overlapping substrate specificity coexist in E. coli O86:B7
Biochem. Biophys. Res. Commun.
356
604-609
2007
Escherichia coli
Guo, H.; Li, L.; Wang, P.G.
Biochemical characterization of UDP-GlcNAc/Glc 4-epimerase from Escherichia coli O86:B7
Biochemistry
45
13760-13768
2006
Escherichia coli, Escherichia coli O86:B7
Agarwal, S.; Gopal, K.; Upadhyaya, T.; Dixit, A.
Biochemical and functional characterization of UDP-galactose 4-epimerase from Aeromonas hydrophila
Biochim. Biophys. Acta
1774
828-837
2007
Aeromonas hydrophila
Urbaniak, M.D.; Tabudravu, J.N.; Msaki, A.; Matera, K.M.; Brenk, R.; Jaspars, M.; Ferguson, M.A.
Identification of novel inhibitors of UDP-Glc 4-epimerase, a validated drug target for african sleeping sickness
Bioorg. Med. Chem. Lett.
16
5744-5747
2006
Homo sapiens, Trypanosoma brucei, Homo sapiens CHO-K1
Zhang, H.C.; Bi, J.Y.; Chen, C.; Huang, G.L.; Qi, Q.S.; Xiao, M.; Wang, P.G.
Immobilization of UDP-galactose 4-epimerase from Escherichia coli on the yeast cell surface
Biosci. Biotechnol. Biochem.
70
2303-2306
2006
Escherichia coli
Roodt, Y.; Bragg, R.; Albertyn, J.
The cloning and sequencing of the UDP-galactose 4-epimerase gene (galE) from Avibacterium paragallinarum
DNA Seq.
18
265-268
2007
Avibacterium paragallinarum
Urbaniak, M.D.; Turnock, D.C.; Ferguson, M.A.
Galactose starvation in a bloodstream form Trypanosoma brucei UDP-glucose 4-epimerase conditional null mutant
Eukaryot. Cell
5
1906-1913
2006
Trypanosoma brucei
Scott, A.; Timson, D.J.
Characterization of the Saccharomyces cerevisiae galactose mutarotase/UDP-galactose 4-epimerase protein, Gal10p
FEMS Yeast Res.
7
366-371
2007
Saccharomyces cerevisiae
Singh, V.; Satheesh, S.V.; Raghavendra, M.L.; Sadhale, P.P.
The key enzyme in galactose metabolism, UDP-galactose-4-epimerase, affects cell-wall integrity and morphology in Candida albicans even in the absence of galactose
Fungal Genet. Biol.
44
563-574
2007
Candida albicans, Schizosaccharomyces pombe (Q9HDU3)
Barber, C.; Roesti, J.; Rawat, A.; Findlay, K.; Roberts, K.; Seifert, G.J.
Distinct properties of the five UDP-D-glucose/UDP-D-galactose 4-epimerase isoforms of Arabidopsis thaliana
J. Biol. Chem.
281
17276-17285
2006
Arabidopsis thaliana
Wasilenko, J.; Fridovich-Keil, J.L.
Relationship between UDP-galactose 4-epimerase activity and galactose sensitivity in yeast
J. Biol. Chem.
281
8443-8449
2006
Saccharomyces cerevisiae
Ban, Y.; Honda, C.; Bessho, H.; Pang, X.M.; Moriguchi, T.
Suppression subtractive hybridization identifies genes induced in response to UV-B irradiation in apple skin: isolation of a putative UDP-glucose 4-epimerase
J. Exp. Bot.
58
1825-1834
2007
Malus domestica
Roesti, J.; Barton, C.J.; Albrecht, S.; Dupree, P.; Pauly, M.; Findlay, K.; Roberts, K.; Seifert, G.J.
UDP-glucose 4-epimerase isoforms UGE2 and UGE4 cooperate in providing UDP-galactose for cell wall biosynthesis and growth of Arabidopsis thaliana
Plant Cell
19
1565-1579
2007
Arabidopsis thaliana
Siddique, S.; Endres, S.; Atkins, J.M.; Szakasits, D.; Wieczorek, K.; Hofmann, J.; Blaukopf, C.; Urwin, P.E.; Tenhaken, R.; Grundler, F.M.; Kreil, D.P.; Bohlmann, H.
Myo-inositol oxygenase genes are involved in the development of syncytia induced by Heterodera schachtii in Arabidopsis roots
New Phytol.
184
457-472
2009
Arabidopsis thaliana (Q42605), Arabidopsis thaliana (Q8LDN8), Arabidopsis thaliana (Q9C7W7), Arabidopsis thaliana (Q9SN58), Arabidopsis thaliana (Q9T0A7)
Niou, Y.K.; Wu, W.L.; Lin, L.C.; Yu, M.S.; Shu, H.Y.; Yang, H.H.; Lin, G.H.
Role of galE on biofilm formation by Thermus spp.
Biochem. Biophys. Res. Commun.
390
313-318
2009
Thermus thermophilus, Thermus aquaticus
Kotake, T.; Takata, R.; Verma, R.; Takaba, M.; Yamaguchi, D.; Orita, T.; Kaneko, S.; Matsuoka, K.; Koyama, T.; Reiter, W.D.; Tsumuraya, Y.
Bifunctional cytosolic UDP-glucose 4-epimerases catalyse the interconversion between UDP-D-xylose and UDP-L-arabinose in plants
Biochem. J.
424
169-177
2009
Pisum sativum (B0M3E8), Pisum sativum, Arabidopsis thaliana (Q42605), Arabidopsis thaliana (Q8LDN8), Arabidopsis thaliana (Q9C7W7), Arabidopsis thaliana (Q9SN58), Arabidopsis thaliana (Q9T0A7)
Prodan-Zitnik, I.; Karas-Kuzelicki, N.; Lukac-Bajalo, J.
Positive correlation between galactose-1-phosphate uridyltransferase (GALT) and UDP-galactose-4-epimerase (GALE) activities
Clin. Biochem.
42
1561-1564
2009
Homo sapiens
Bang, Y.L.; Nguyen, T.T.; Trinh, T.T.; Kim, Y.J.; Song, J.; Song, Y.H.
Functional analysis of mutations in UDP-galactose-4-epimerase (GALE) associated with galactosemia in Korean patients using mammalian GALE-null cells
FEBS J.
276
1952-1961
2009
Homo sapiens (Q14376), Homo sapiens
Brahma, A.; Banerjee, N.; Bhattacharyya, D.
UDP-galactose 4-epimerase from Kluyveromyces fragilis - catalytic sites of the homodimeric enzyme are functional and regulated
FEBS J.
276
6725-6740
2009
Kluyveromyces marxianus
El-Ganiny, A.M.; Sheoran, I.; Sanders, D.A.; Kaminskyj, S.G.
Aspergillus nidulans UDP-glucose-4-epimerase UgeA has multiple roles in wall architecture, hyphal morphogenesis, and asexual development
Fungal Genet. Biol.
47
629-635
2010
Aspergillus nidulans
Dong, S.; Chesnokova, O.N.; Turnbough, C.L.; Pritchard, D.G.
Identification of the UDP-N-acetylglucosamine 4-epimerase involved in exosporium protein glycosylation in Bacillus anthracis
J. Bacteriol.
191
7094-7101
2009
Bacillus anthracis (Q81JK4), Bacillus anthracis (Q81K34), Bacillus anthracis
Suzuki, S.; Matsuzawa, T.; Nukigi, Y.; Takegawa, K.; Tanaka, N.
Characterization of two different types of UDP-glucose/-galactose 4-epimerase involved in galactosylation in fission yeast
Microbiology
156
708-718
2010
Schizosaccharomyces pombe (Q9Y7X5), Schizosaccharomyces pombe, Schizosaccharomyces pombe ARC039 (Q9Y7X5)
Ban, Y.; Kondo, S.; Ubi, B.E.; Honda, C.; Bessho, H.; Moriguchi, T.
UDP-sugar biosynthetic pathway: contribution to cyanidin 3-galactoside biosynthesis in apple skin
Planta
230
871-881
2009
Malus domestica
Kim, H.J.; Kang, S.Y.; Park, J.J.; Kim, P.
Novel activity of UDP-galactose-4-epimerase for free monosaccharide and activity improvement by active site-saturation mutagenesis
Appl. Biochem. Biotechnol.
163
444-451
2011
Escherichia coli (P09147), Escherichia coli
Sakuraba, H.; Kawai, T.; Yoneda, K.; Ohshima, T.
Crystal structure of UDP-galactose 4-epimerase from the hyperthermophilic archaeon Pyrobaculum calidifontis
Arch. Biochem. Biophys.
51
126-134
2011
Pyrobaculum calidifontis (A3MUJ4), Pyrobaculum calidifontis
McCorvie, T.J.; Wasilenko, J.; Liu, Y.; Fridovich-Keil, J.L.; Timson, D.J.
In vivo and in vitro function of human UDP-galactose 4-epimerase variants
Biochimie
93
1747-1754
2011
Homo sapiens
Agarwal, S.; Mishra, N.; Agarwal, S.; Dixit, A.
Characterization of the active site and coenzyme binding pocket of the monomeric UDP-galactose 4'-epimerase of Aeromonas hydrophila
BMB Rep.
43
419-426
2010
Aeromonas hydrophila
Chung, S.K.; Ryu, S.I.; Lee, S.B.
Characterization of UDP-glucose 4-epimerase from Pyrococcus horikoshii: regeneration of UDP to produce UDP-galactose using two-enzyme system with trehalose
Biores. Technol.
110
423-429
2012
Pyrococcus horikoshii (O73960), Pyrococcus horikoshii, Pyrococcus horikoshii OT-3 (O73960)
Frey, P.A.; Hegeman, A.D.
Chemical and stereochemical actions of UDP-galactose 4-epimerase
Acc. Chem. Res.
46
1417-1426
2013
Escherichia coli
Dalrymple, S.A.; Sheoran, I.; Kaminskyj, S.G.; Sanders, D.A.
Preliminary X-ray crystallographic studies of UDP-glucose-4-epimerase from Aspergillus nidulans
Acta Crystallogr. Sect. F
67
885-887
2011
Aspergillus nidulans (C8VAU8), Aspergillus nidulans
Beerens, K.; Soetaert, W.; Desmet, T.
Characterization and mutational analysis of the UDP-Glc(NAc) 4-epimerase from Marinithermus hydrothermalis
Appl. Microbiol. Biotechnol.
97
7733-7740
2013
Marinithermus hydrothermalis
Lee, M.J.; Gravelat, F.N.; Cerone, R.P.; Baptista, S.D.; Campoli, P.V.; Choe, S.I.; Kravtsov, I.; Vinogradov, E.; Creuzenet, C.; Liu, H.; Berghuis, A.M.; Latge, J.P.; Filler, S.G.; Fontaine, T.; Sheppard, D.C.
Overlapping and distinct roles of Aspergillus fumigatus UDP-glucose 4-epimerases in galactose metabolism and the synthesis of galactose-containing cell wall polysaccharides
J. Biol. Chem.
289
1243-1256
2014
Aspergillus fumigatus, Aspergillus fumigatus Af293
Li, C.T.; Liao, C.T.; Du, S.C.; Hsiao, Y.P.; Lo, H.H.; Hsiao, Y.M.
Functional characterization and transcriptional analysis of galE gene encoding a UDP-galactose 4-epimerase in Xanthomonas campestris pv. campestris
Microbiol. Res.
169
441-452
2013
Xanthomonas campestris, Xanthomonas campestris Xc17
Liu, P.; Shi, Y.; Yang, Y.; Cao, Y.; Shi, Y.; Li, H.; Liu, J.; Lin, J.; Jin, Y.
Schistosoma japonicum UDP-glucose 4-epimerase protein is located on the tegument and induces moderate protection against challenge infection
PLoS ONE
7
e42050
2012
Schistosoma japonicum (Q5D9E1), Schistosoma japonicum
Dalrymple, S.A.; Ko, J.; Sheoran, I.; Kaminskyj, S.G.; Sanders, D.A.
Elucidation of substrate specificity in Aspergillus nidulans UDP-galactose-4-epimerase
PLoS ONE
8
e76803
2013
Aspergillus nidulans (C8VAU8), Aspergillus nidulans
Shin, S.; Choi, J.; Di Luccio, E.; Lee, Y.; Lee, S.; Lee, S.; Lee, S.; Lee, D.
The structural basis of substrate promiscuity in UDP-hexose 4-epimerase from the hyperthermophilic Eubacterium Thermotoga maritima
Arch. Biochem. Biophys.
585
39-51
2015
Thermotoga maritima (Q9WYX9), Thermotoga maritima, Thermotoga maritima DSM 3109 (Q9WYX9), Thermotoga maritima ATCC 43589 / MSB8 / DSM 3109 / JCM 10099 (Q9WYX9)
Wen, Y.; Qin, J.; Deng, Y.; Wang, H.; Magdalou, J.; Chen, L.
The critical role of UDP-galactose-4-epimerase in osteoarthritis modulating proteoglycans synthesis of the articular chondrocytes
Biochem. Biophys. Res. Commun.
452
906-911
2014
Homo sapiens (Q14376), Homo sapiens
Chen, L.L.; Han, D.L.; Zhai, Y.F.; Wang, J.H.; Wang, Y.F.; Chen, M.
Characterization and mutational analysis of two UDP-galactose 4-epimerases in Streptococcus pneumoniae TIGR4
Biochemistry (Moscow)
83
37-44
2018
Streptococcus pneumoniae (A0A0H2UQY4), Streptococcus pneumoniae (A0A0H2URG4), Streptococcus pneumoniae, Streptococcus pneumoniae ATCC BAA-334 / TIGR4 (A0A0H2UQY4), Streptococcus pneumoniae ATCC BAA-334 / TIGR4 (A0A0H2URG4)
Beerens, K.; Soetaert, W.; Desmet, T.
UDP-hexose 4-epimerases a view on structure, mechanism and substrate specificity
Carbohydr. Res.
414
8-14
2015
Marinithermus hydrothermalis (F2NQX6), Thermus thermophilus (F6DEY6), Saccharomyces cerevisiae (P04397), Escherichia coli (P09147), Streptococcus thermophilus (P21977), Homo sapiens (Q14376), Homo sapiens, Drosophila melanogaster (Q9W0P5), Saccharomyces cerevisiae ATCC 204508 / S288c (P04397), Thermus thermophilus SG0.5JP17-16 (F6DEY6), Marinithermus hydrothermalis DSM 14884 / JCM 11576 / T1 (F2NQX6)
Park, J.; Tefsen, B.; Arentshorst, M.; Lagendijk, E.; van den Hondel, C.A.; van Die, I.; Ram, A.F.
Identification of the UDP-glucose-4-epimerase required for galactofuranose biosynthesis and galactose metabolism in A. niger
Fungal Biol. Biotechnol.
1
6
2014
Aspergillus niger (A2R3C7), Aspergillus niger CBS 513.88 / FGSC A1513 (A2R3C7)
Wang, S.; Ito, T.; Uehara, M.; Naito, S.; Takano, J.
UDP-D-galactose synthesis by UDP-glucose 4-epimerase 4 is required for organization of the trans-Golgi network/early endosome in Arabidopsis thaliana root epidermal cells
J. Plant Res.
128
863-873
2015
Arabidopsis thaliana (Q9C7W7), Arabidopsis thaliana, Arabidopsis thaliana Col-0 (Q9C7W7)
Pardeshi, P.; Rao, K.K.; Balaji, P.V.
Rv3634c from Mycobacterium tuberculosis H37Rv encodes an enzyme with UDP-Gal/Glc and UDP-GalNAc 4-epimerase activities
PLoS ONE
12
e0175193
2017
Mycobacterium tuberculosis (P9WN67), Mycobacterium tuberculosis H37Rv (P9WN67), Mycobacterium tuberculosis H37Rv
Guevara, D.R.; El-Kereamy, A.; Yaish, M.W.; Mei-Bi, Y.; Rothstein, S.J.
Functional characterization of the rice UDP-glucose 4-epimerase 1, OsUGE1 a potential role in cell wall carbohydrate partitioning during limiting nitrogen conditions
PLoS ONE
9
e96158
2014
Oryza sativa Japonica Group (Q8LNZ3)
Yin, S.; Kong, J.
Transcriptome-guided discovery and functional characterization of two UDP-sugar 4-epimerase families involved in the biosynthesis of anti-tumor polysaccharides in Ornithogalum caudatum
RSC Adv.
6
37370-37384
2016
Albuca bracteata (A0A168GPL0), Albuca bracteata (A0A168GPR3)
-
Shah, B.; Ashwood, H.; Harrop, S.; Farrugia, D.; Paulsen, I.; Mabbutt, B.
Crystal structure of a UDP-GlcNAc epimerase for surface polysaccharide biosynthesis in Acinetobacter baumannii
PLoS ONE
13
e0191610
2018
Acinetobacter baumannii (V5RBP5), Acinetobacter baumannii, Acinetobacter baumannii Dl279779 (V5RBP5)
html completed
