Reference on EC 5.1.1.13 - aspartate racemase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Adams, E.
Amino acid racemases and epimerases
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
6
479-507
1972
Limosilactobacillus fermentum, Pseudomonas sp.
-
Lamont, H.C.; Staudenbauer, W.L.; Strominger, J.L.
Partial purification and characterization of an aspartate racemase from Streptococcus faecalis
J. Biol. Chem.
247
5103-5106
1972
Enterococcus faecalis
Yamaguchi, T.; Choi, S.Y.; Okada, H.; Yohda, M.; Kumagai, H.; Esaki, N.; Soda, K.
Properties of aspartate racemase, a pyridoxal 5'-phosphate-independent amino acid racemase
J. Biol. Chem.
267
18361-18364
1992
Streptococcus thermophilus
Okada, H.; Yohda, M.; Giga-Hama, Y.; Ueno, Y.; Ohdo, S.; Kumagai, H.
Distribution and purification of asparate racemase in lactic acid bacteria
Biochim. Biophys. Acta
1078
377-382
1991
Enterococcus faecalis, Enterococcus faecium, Levilactobacillus brevis, Lactobacillus delbrueckii subsp. bulgaricus, Lacticaseibacillus casei, Lactobacillus delbrueckii, Lactococcus lactis, no activity in Bifidobacterium bifidum, no activity in Leuconostoc mesenteroides, no activity in Pediococcus pentosaceus, Streptococcus thermophilus
Soda, K.
PLP-dependent and independent amino acid racemase
Enzymes Depend. Pyridoxal Phosphate Other Carbonyl Comp. Cofactors (Proc. Int. Symp. Vitam. B6 Carbonyl Catal. , Meeting Date 1990, Fukui T. , ed. ) Pergamon, Oxford
8
29-34
1991
Enterococcus faecalis, Streptococcus thermophilus
-
Yohda, M.; Endo, I.; Abe, Y.; Ohta, T.; Iida, T.; Maruyama, T.; Kagawa, Y.
Gene for aspartate racemase from the sulfur-dependent hyperthermophilic archaeum, Desulfurococcus strain SY
J. Biol. Chem.
271
22017-22021
1996
Desulfurococcus sp., Desulfurococcus sp. SY
Yohda, M.; Okada, H.; Kumagai, H.
Molecular cloning and nucleotide sequencing of the aspartate racemase gene from lactic acid bacteria Streptococcus thermophilus
Biochim. Biophys. Acta
1089
234-240
1991
Streptococcus thermophilus
Ohtani, S.
Estimation of age from dentin by using the racemization reaction of aspartic acid
Am. J. Forensic Med. Pathol.
16
158-161
1995
Bacteria
Liu, L.; Iwata, K.; Kawarabayasi, Y.; Kikuchi, H.; Kita, A.; Yohda, M.; Miki, K.
Crystallization and preliminary X-ray analysis of aspartate racemase from Pyrococcus horikoshii OT3
Acta Crystallogr. Sect. D
57
1674-1676
2001
Pyrococcus horikoshii OT3
Sielaff, H.; Dittmann, E.; Tandeau De Marsac, N.; Bouchier, C.; Von Dohren, H.; Borner, T.; Schwecke, T.
The mcyF gene of the microcystin biosynthetic gene cluster from Microcystis aeruginosa encodes an aspartate racemase
Biochem. J.
373
909-916
2003
Microcystis aeruginosa
Shibata, K.; Watanabe, T.; Yoshikawa, H.; Abe, K.; Takahashi, S.; Kera, Y.; Yamada, R.H.
Purification and characterization of aspartate racemase from the bivalve mollusk Scapharca broughtonii
Comp. Biochem. Physiol. B
134
307-314
2003
Anadara broughtonii
Shibata, K.; Watanabe, T.; Yoshikawa, H.; Abe, K.; Takahashi, S.; Kera, Y.; Yamada, R.H.
Nucleotides modulate the activity of aspartate racemase of Scapharca broughtonii
Comp. Biochem. Physiol. B
134
713-719
2003
Anadara broughtonii
Liu, L.; Iwata, K.; Kita, A.; Kawarabayasi, Y.; Yohda, M.; Miki, K.
Crystal structure of aspartate racemase from Pyrococcus horikoshii OT3 and its implications for molecular mechanism of PLP-independent racemization
J. Mol. Biol.
319
479-489
2002
Pyrococcus horikoshii OT3
D'Aniello, S.; Spinelli, P.; Ferrandino, G.; Peterson, K.; Tsesarskia, M.; Fisher, G.; D'Aniello, A.
Cephalopod vision involves dicarboxylic amino acids: D-aspartate, L-aspartate and L-glutamate
Biochem. J.
386
331-340
2005
Sepia officinalis
Yamashita, T.; Ashiuchi, M.; Ohnishi, K.; Kato, S.; Nagata, S.; Misono, H.
Molecular identification of monomeric aspartate racemase from Bifidobacterium bifidum
Eur. J. Biochem.
271
4798-4803
2004
Bifidobacterium bifidum, Bifidobacterium bifidum NBRC 14252
Raucci, F.; Santillo, A.; D'Aniello, A.; Chieffi, P.; Baccari, G.C.
D-Aspartate modulates transcriptional activity in Harderian gland of frog, Rana esculenta: Morphological and molecular evidence
J. Cell. Physiol.
204
445-454
2005
Pelophylax lessonae
Spinelli, P.; Brown, E.R.; Ferrandino, G.; Branno, M.; Montarolo, P.G.; D'Aniello, E.; Rastogi, R.K.; D'Aniello, B.; Baccari, G.C.; Fisher, G.; D'Aniello, A.
D-aspartic acid in the nervous system of Aplysia limacina: Possible role in neurotransmission
J. Cell. Physiol.
206
672-681
2006
Aplysia limacina
Abe, K.; Takahashi, S.; Muroki, Y.; Kera, Y.; Yamada, R.
Cloning and expression of the pyridoxal 5-phosphate-dependent aspartate racemase gene from the bivalve mollusk Scapharca broughtonii and characterization of the recombinant enzyme
J. Biochem.
139
235-244
2006
Anadara broughtonii
Ohtaki, A.; Nakano, Y.; Iizuka, R.; Arakawa, T.; Yamada, K.; Odaka, M.; Yohda, M.
Structure of aspartate racemase complexed with a dual substrate analogue, citric acid, and implications for the reaction mechanism
Proteins Struct. Funct. Bioinform.
70
1167-1174
2008
Pyrococcus horikoshii (O58403), Pyrococcus horikoshii OT-3 (O58403)
Kim, P.M.; Duan, X.; Huang, A.S.; Liu, C.Y.; Ming, G.L.; Song, H.; Snyder, S.H.
Aspartate racemase, generating neuronal D-aspartate, regulates adult neurogenesis
Proc. Natl. Acad. Sci. USA
107
3175-3179
2010
Mus musculus
Topo, E.; Soricelli, A.; DAniello, A.; Ronsini, S.; DAniello, G.
The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats
Reprod. Biol. Endocrinol.
7
120-130
2009
Rattus norvegicus
Zhang, C.; Guo, Y.; Xue, Y.
QM/MM study on catalytic mechanism of aspartate racemase from Pyrococcus horikoshii OT3
Theoret. Chem. Accounts
129
781-791
2011
Pyrococcus horikoshii, Pyrococcus horikoshii OT-3
-
Long, Z.; Lee, J.A.; Okamoto, T.; Sekine, M.; Nimura, N.; Imai, K.; Yohda, M.; Maruyama, T.; Sumi, M.; Kamo, N.; Yamagishi, A.; Oshima, T.; Homma, H.
Occurrence of D-amino acids and a pyridoxal 5'-phosphate-dependent aspartate racemase in the acidothermophilic archaeon, Thermoplasma acidophilum
Biochem. Biophys. Res. Commun.
281
317-321
2001
Thermoplasma acidophilum, Thermoplasma acidophilum HO-62
Ohide, H.; Miyoshi, Y.; Maruyama, R.; Hamase, K.; Konno, R.
D-Amino acid metabolism in mammals: biosynthesis, degradation and analytical aspects of the metabolic study
J. Chromatogr. B
879
3162-3168
2011
Mus musculus, Rattus norvegicus
Fujii, T.; Yamauchi, T.; Ishiyama, M.; Gogami, Y.; Oikawa, T.; Hata, Y.
Crystallographic studies of aspartate racemase from Lactobacillus sakei NBRC 15893
Acta Crystallogr. Sect. F
71
1012-1016
2015
Latilactobacillus sakei, Latilactobacillus sakei NBRC 15893
Mizobuchi, T.; Nonaka, R.; Yoshimura, M.; Abe, K.; Takahashi, S.; Kera, Y.; Goto, M.
Crystal structure of a pyridoxal 5'-phosphate-dependent aspartate racemase derived from the bivalve mollusc Scapharca broughtonii
Acta Crystallogr. Sect. F
73
651-656
2017
Anadara broughtonii
Tanaka-Hayashi, A.; Hayashi, S.; Inoue, R.; Ito, T.; Konno, K.; Yoshida, T.; Watanabe, M.; Yoshimura, T.; Mori, H.
Is D-aspartate produced by glutamic-oxaloacetic transaminase-1 like 1 (Got1l1) a putative aspartate racemase?
Amino Acids
47
79-86
2015
Mus musculus (Q7TSV6), Mus musculus
Matsuda, S.; Katane, M.; Maeda, K.; Kaneko, Y.; Saitoh, Y.; Miyamoto, T.; Sekine, M.; Homma, H.
Biosynthesis of D-aspartate in mammals the rat and human homologs of mouse aspartate racemase are not responsible for the biosynthesis of D-aspartate
Amino Acids
47
975-985
2015
Homo sapiens, Rattus norvegicus
Uda, K.; Abe, K.; Dehara, Y.; Mizobata, K.; Edashige, Y.; Nishimura, R.; Radkov, A.D.; Moe, L.A.
Triple serine loop region regulates the aspartate racemase activity of the serine/aspartate racemase family
Amino Acids
49
1743-1754
2017
Penaeus monodon (A0A0U5A554), Acropora millepora (JT020910), Crassostrea gigas (K1QH67)
Aihara, T.; Ito, T.; Yamanaka, Y.; Noguchi, K.; Odaka, M.; Sekine, M.; Homma, H.; Yohda, M.
Structural and functional characterization of aspartate racemase from the acidothermophilic archaeon Picrophilus torridus
Extremophiles
20
385-393
2016
Picrophilus torridus (Q6L2R8), Picrophilus torridus, Picrophilus torridus ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828 (Q6L2R8)
Washio, T.; Kato, S.; Oikawa, T.
Molecular cloning and enzymological characterization of pyridoxal 5'-phosphate independent aspartate racemase from hyperthermophilic archaeon Thermococcus litoralis DSM 5473
Extremophiles
20
711-721
2016
Thermococcus litoralis (H3ZNI2), Thermococcus litoralis, Thermococcus litoralis ATCC 51850 / DSM 5473 / JCM 8560 / NS-C (H3ZNI2)
Katane, M.; Nakayama, K.; Kawata, T.; Yokoyama, Y.; Matsui, Y.; Kaneko, Y.; Matsuda, S.; Saitoh, Y.; Miyamoto, T.; Sekine, M.; Homma, H.
A sensitive assay for measuring aspartate-specific amino acid racemase activity
J. Pharm. Biomed. Anal.
116
109-115
2015
Streptococcus thermophilus
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