Any feedback?
Please rate this page
(enzyme.php)
(0/150)

BRENDA support

Disease on EC 4.6.1.24 - ribonuclease T1

Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma
[Bacillus pumilus Ribonuclease Inhibits Migration of Human Duodenum Adenocarcinoma HuTu 80 Cells].
Adenocarcinoma of Lung
Nano-Scaled Zeolitic Imidazole Framework-8 as an Efficient Carrier for the Intracellular Delivery of RNase A in Cancer Treatment.
[Combined action of binase and bleomycin toward human lung adenocarcinoma cells].
[Identification of 2',3'-cGMP as an intermediate of RNA catalytic cleavage by binase and evaluation of its biological action].
Adenocarcinoma, Bronchiolo-Alveolar
Internalization of Bacillus intermedius ribonuclease (BINASE) induces human alveolar adenocarcinoma cell death.
Adenoma
Mutational analysis of the extracellular Ca(2+)-sensing receptor gene in human parathyroid tumors.
Amyotrophic Lateral Sclerosis
A new role for angiogenin in neurite growth and pathfinding: implications for amyotrophic lateral sclerosis.
Structural and functional implications of positive selection at the primate angiogenin gene.
Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons.
Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis.
Asthma
"The (1)H, (13)C, (15)N resonance assignment, solution structure and residue level stability of eosinophil cationic protein/rnase 3 determined by NMR spectroscopy"
Bluetongue
Expression and functional characterization of bluetongue virus VP2 protein: role in cell entry.
Oligonucleotide fingerprint analysis of the genomes of two variants of bluetongue virus serotype 2 isolated in the U.S.A.
Brain Neoplasms
Differential expression in glioblastoma multiforme and cerebral hemangioblastoma of cytoplasmic proteins that bind two different domains within the 3'-untranslated region of the human glucose transporter 1 (GLUT1) messenger RNA.
Breast Neoplasms
High-performance hydrophobic interaction chromatography as a means of identifying estrogen receptors expressing different binding domains.
Hypoxia-sensitive supramolecular nanogels for the cytosolic delivery of ribonuclease A as a breast cancer therapeutic.
Luteinizing hormone releasing hormone-RNase A conjugates specifically inhibit the proliferation of LHRH-receptor-positive human prostate and breast tumor cells.
Carcinoma
Barnase as a new therapeutic agent triggering apoptosis in human cancer cells.
Binase treatment increases interferon sensitivity and apoptosis in SiHa cervical carcinoma cells by downregulating E6 and E7 human papilloma virus oncoproteins.
Folic acid conjugated and Ag-carrying organoclay nanoparticles and their response to L929 fibroblast and DLD-1 cancer cells.
Lipo-Oligomer Nanoformulations for Targeted Intracellular Protein Delivery.
MicroRNA drop in the bloodstream and microRNA boost in the tumour caused by treatment with ribonuclease A leads to an attenuation of tumour malignancy.
Modification of ribonucleic acid by vitamin B6. 1. Specific interaction of pyridoxal 5'-phosphate with transfer ribonucleic acid.
Mutational analysis of the extracellular Ca(2+)-sensing receptor gene in human parathyroid tumors.
Ribonuclease binase decreases destructive changes of the liver and restores its regeneration potential in mouse lung carcinoma model.
Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells.
The systemic tumor response to RNase A treatment affects the expression of genes involved in maintaining cell malignancy.
Tumoricidal Activity of RNase A and DNase I.
Carcinoma, Hepatocellular
Effect of dimerized ribonuclease A on the intracellular localization of exogenous proteins taken up from the culture medium by hepatoma cells [proceedings]
Effects of cross-linked dimers of ribonuclease A or of lysozyme on the processing of endocytosed peroxidase by hepatoma cells.
Inhibition of protein degradation induced by dimeric ribonuclease A in hepatoma cells [proceedings]
Inhibition of the discharge of endocytosed protein from phagosomes into lysosomes in hepatoma cells exposed to dimerized ribonuclease A.
Tumoricidal Activity of RNase A and DNase I.
Carcinoma, Lewis Lung
MicroRNA drop in the bloodstream and microRNA boost in the tumour caused by treatment with ribonuclease A leads to an attenuation of tumour malignancy.
Ribonuclease binase decreases destructive changes of the liver and restores its regeneration potential in mouse lung carcinoma model.
Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells.
The systemic tumor response to RNase A treatment affects the expression of genes involved in maintaining cell malignancy.
Tumoricidal Activity of RNase A and DNase I.
Carcinoma, Squamous Cell
Cross-linked trimers of bovine ribonuclease A: activity on double-stranded RNA and antitumor action.
Mesoporous carbon hollow spheres: carbonisation-temperature-dependent delivery of therapeutic proteins.
Colonic Neoplasms
Binase Immobilized on Halloysite Nanotubes Exerts Enhanced Cytotoxicity toward Human Colon Adenocarcinoma Cells.
Production and characterization of scFvA33T1, an immunoRNase targeting colon cancer cells.
Water-soluble Ru(II)- and Ru(III)-halide-PTA complexes (PTA=1,3,5-triaza-7-phosphaadamantane): Chemical and biological properties.
Conjunctivitis
Oligonucleotide fingerprint analysis of enterovirus 70 isolates from the 1980 to 1981 pandemic of acute hemorrhagic conjunctivitis: evidence for a close genetic relationship among Asian and American strains.
Conjunctivitis, Acute Hemorrhagic
Oligonucleotide fingerprint analysis of enterovirus 70 isolates from the 1980 to 1981 pandemic of acute hemorrhagic conjunctivitis: evidence for a close genetic relationship among Asian and American strains.
Dehydration
Fast-painting of human metaphase spreads using a chromosome-specific, repeat-depleted DNA library probe.
Modeling formalin fixation and histological processing with ribonuclease A: effects of ethanol dehydration on reversal of formaldehyde cross-links.
Dengue
Characterization of the viral RNA species of prototype dengue viruses.
Genetic and epidemiological studies of dengue type 2 viruses by hybridization using synthetic deoxyoligonucleotides as probes.
Diphtheria
Exploiting the Intron-splicing Mechanism of Insect Cells to Produce Viral Vectors Harboring Toxic Genes for Suicide Gene Therapy.
Production of Viral Vectors with Suicide Genes by Utilizing the Intron-Splicing Mechanism of Insect Cells.
The second intron of AGAMOUS drives carpel- and stamen-specific expression sufficient to induce complete sterility in Arabidopsis.
Encephalitis
A comparison of Saint Louis encephalitis and Sindbis virus RNA.
Genetic variation of Murray Valley encephalitis virus.
Encephalomyelitis
Proteins induced in tissue culture by four isolates of Theiler's murine encephalomyelitis virus.
Theiler's murine encephalomyelitis virus group includes two distinct genetic subgroups that differ pathologically and biologically.
Encephalomyelitis, Venezuelan Equine
Genetic variation of Venezuelan equine encephalitis virus strains of the ID variety in Colombia.
Immunochemical and oligonucleotide fingerprint analyses of Venezuelan equine encephalomyelitis complex viruses.
Food Hypersensitivity
Evaluation of Bar, Barnase, and Barstar recombinant proteins expressed in genetically engineered Brassica juncea (Indian mustard) for potential risks of food allergy using bioinformatics and literature searches.
Foot-and-Mouth Disease
Application of RNase T1 one- and two-dimensional analyses to the rapid identification of foot-and-mouth disease viruses.
Detection of T1-oligonucleotides of the foot-and-mouth disease virus RNA [correction of DNA] by silver staining.
Variation in foot-and-mouth disease virus isolates in Kenya: an examination of field isolates by T1 oligonucleotide fingerprinting.
Fragile X Syndrome
Denaturing polyacrylamide gel electrophoresis.
Genetic Diseases, Inborn
Detection of point mutations associated with genetic diseases by an exon scanning technique.
Glioblastoma
Cytotoxic ribonuclease chimeras. Targeted tumoricidal activity in vitro and in vivo.
Glioma
Characterization of the epidermal growth factor receptor in human glioma cell lines and xenografts.
Cis-element/cytoplasmic protein interaction within the 3'-untranslated region of the GLUT1 glucose transporter mRNA.
Hepatitis
Cloning and sequencing of 5' terminal sequences from avian infectious bronchitis virus genomic RNA.
DNA- and RNA-hydrolyzing antibodies from the blood of patients with various forms of viral hepatitis.
Metal ions: supporting actors in the playbook of small ribozymes.
Multiscale methods for computational RNA enzymology.
Hepatitis A
Variation among hepatitis A virus strains. I. Genomic variation detected by T1 oligonucleotide mapping.
Hepatitis B
Sensitive Detection of RNase A Activity and Collaborative Drug Screening Based on rGO and Fluorescence Probe.
Herpes Simplex
Comparative study of the genetic variability in thymidine kinase and glycoprotein B genes of herpes simplex viruses by the RNase A mismatch cleavage method.
Genetic analysis of herpes simplex virus type 1 isolates from recurrent lesions and clinical reinfections.
The virion host shutoff protein (UL41) of herpes simplex virus 1 is an endoribonuclease with a substrate specificity similar to that of RNase A.
HIV Infections
Inhibition of HIV-1 infection by small interfering RNA-mediated RNA interference.
Hypercalcemia
Mutational analysis of the extracellular Ca(2+)-sensing receptor gene in human parathyroid tumors.
Hyperglycemia
Polysaccharides of a fermented food, natto, suppress sucrose-induced hyperglycemia in an in vivo evaluation system and inhibit glucose uptake by human intestinal cells.
Hyperparathyroidism, Secondary
No evidence for mutations in the calcium-sensing receptor gene in sporadic parathyroid adenomas.
Hypersensitivity
"The (1)H, (13)C, (15)N resonance assignment, solution structure and residue level stability of eosinophil cationic protein/rnase 3 determined by NMR spectroscopy"
Isolation of Saccharomyces cerevisiae RNase T1 hypersensitive (rns) mutants and genetic analysis of the RNS1/DSL1 gene.
Infections
A new strategy for generating geminivirus resistant plants using a DNA betasatellite/split barnase construct.
Anti-Influenza Activity of the Ribonuclease Binase: Cellular Targets Detected by Quantitative Proteomics.
Baculovirus-mediated gene transfer into mammalian cells.
Crystal Structures of the Nicotiana glutinosa Ribonuclease NT in Complex with Nucleoside Monophosphates.
Enzymatic activities and effects of mycovirus infection on the virulence of Metarhizium anisopliae in Rhipicephalus microplus.
Exploring the mechanisms of action of human secretory RNase 3 and RNase 7 against Candida albicans.
Formation of bacteriophage MS2 infectious units in a cell-free translation system.
Genetic variation of foot-and-mouth disease virus during persistent infection in cattle.
Heterogeneity of the polyribocytidilic acid tract in aphthovirus: changes in the size of the poly(C) of viruses recovered from persistently infected cattle.
Host transfer RNA cleavage and reunion in T4-infected Escherichia coli CTr5x.
Inhibition of Human Papillomavirus Type 16 Infection Using an RNA Aptamer.
Magnetite Nanoparticles Functionalized with RNases against Intracellular Infection of Pseudomonas aeruginosa.
Noncanonical Transmission of a Measles Virus Vaccine Strain from Neurons to Astrocytes.
Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes.
Ribonuclease from Bacillus Acts as an Antiviral Agent against Negative- and Positive-Sense Single Stranded Human Respiratory RNA Viruses.
Sensitive Detection of RNase A Activity and Collaborative Drug Screening Based on rGO and Fluorescence Probe.
The 5' end of poliovirus mRNA is not capped with m7G(5')ppp(5')Np.
The Responses of the Ribonuclease A Superfamily to Urinary Tract Infection.
The Ribonuclease A Superfamily in Humans: Canonical RNases as the Buttress of Innate Immunity.
Infertility
Application of Arabidopsis AGAMOUS second intron for the engineered ablation of flower development in transgenic tobacco.
Barnase and Binase: Twins with Distinct Fates.
Bisexual sterility conferred by the differential expression of barnase and barstar: a simple and efficient method of transgene containment.
Creating Completely Both Male and Female Sterile Plants by Specifically Ablating Microspore and Megaspore Mother Cells.
Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract.
Testing a Human Antimicrobial RNase Chimera Against Bacterial Resistance.
The second intron of AGAMOUS drives carpel- and stamen-specific expression sufficient to induce complete sterility in Arabidopsis.
Infertility, Male
A novel, two-component system for cell lethality and its use in engineering nuclear male-sterility in plants.
Development and characterization of transgenic dominant male sterile rice toward an outcross-based breeding system.
Identification of two highly specific pollen promoters using transcriptomic data.
RTS, a rice anther-specific gene is required for male fertility and its promoter sequence directs tissue-specific gene expression in different plant species.
Split-gene system for hybrid wheat seed production.
The development of a nuclear male sterility system in wheat. Expression of the barnase gene under the control of tapetum specific promoters.
The production of male-sterile wheat plants through split barnase expression is promoted by the insertion of introns and flexible peptide linkers.
Influenza, Human
Analysis of genetic variability and mapping of point mutations in influenza virus by the RNase A mismatch cleavage method.
Anti-Influenza Activity of the Ribonuclease Binase: Cellular Targets Detected by Quantitative Proteomics.
Antiviral Activity of Binase against the Pandemic Influenza A (H1N1) Virus.
Bacterial ribonuclease binase exerts an intra-cellular anti-viral mode of action targeting viral RNAs in influenza a virus-infected MDCK-II cells.
Estimates by computer simulation of genetic distances from comparisons of RNAse A mismatch cleavage patterns.
Influenza virus messenger RNAs are incomplete transcripts of the genome RNAs.
Ribonuclease from Bacillus Acts as an Antiviral Agent against Negative- and Positive-Sense Single Stranded Human Respiratory RNA Viruses.
Screening of influenza mutations using base-specific cleavage and MALDI mass spectrometry.
The use of T1 oligonucleotide mapping to determine that the emergence of Canadian 1973-like and 1974-like H3N2 strains in 1984 was the result of laboratory contamination.
[Action of hydrolytic enzymes on influenza virus A ribonucleoprotein]
Lesch-Nyhan Syndrome
Identification and localization of mutations at the Lesch-Nyhan locus by ribonuclease A cleavage.
Leukemia
Barnase as a new therapeutic agent triggering apoptosis in human cancer cells.
Class II polytropic murine leukemia viruses (MuLVs) of AKR/J mice: possible role in the generation of class I oncogenic polytropic MuLVs.
Construction and use of retroviral vectors encoding the toxic gene barnase.
Effect of the replacement of aspartic acid/glutamic acid residues with asparagine/glutamine residues in RNase He1 from Hericium erinaceus on inhibition of human leukemia cell line proliferation.
Genetic structure and transforming sequence of avian sarcoma virus UR2.
Mechanism of RNA primer removal by the RNase H activity of avian myeloblastosis virus reverse transcriptase.
RNase inhibition of human immunodeficiency virus infection of H9 cells.
Structure of the genome of Moloney murine leukemia virus: a terminally redundant sequence.
T1 oligonucleotide maps of N-, B-, and B leads to NB-tropic murine leukemia viruses derived from BALB/c.
The inhibition of human tumor cell proliferation by RNase Pol, a member of the RNase T1 family, from Pleurotus ostreatus.
[Detection of minimal residual disease in acute lymphoblastic leukemia using PCR-molecule hybridization of RNA transcripts]
Leukemia, Erythroblastic, Acute
X-ray structure of two crystalline forms of a streptomycete ribonuclease with cytotoxic activity.
Leukemia, Myeloid
Water-soluble Ru(II)- and Ru(III)-halide-PTA complexes (PTA=1,3,5-triaza-7-phosphaadamantane): Chemical and biological properties.
Leukemia, Myeloid, Acute
Cytotoxicity of RNase Sa to the acute myeloid leukemia Kasumi-1 cells depends on the net charge.
Sensitivity of acute myeloid leukemia Kasumi-1 cells to binase toxic action depends on the expression of KIT and ?ML1-ETO oncogenes.
Liver Neoplasms
Stability analysis of liver cancer-related microRNAs.
Liver Neoplasms, Experimental
Comparison of RNase T1 fingerprints of U1, U2, and U3 small nuclear RNA's of HeLa cells, human normal fibroblasts, and Novikoff hepatoma cells.
Lung Neoplasms
The systemic tumor response to RNase A treatment affects the expression of genes involved in maintaining cell malignancy.
Lymphoma
Differential expression of the normal and mutated K-ras alleles in chemically induced thymic lymphomas.
Intranuclear network of 3-5 nm and 8-10 nm fibers in EL-4 lymphoma cells.
Lymphoma, B-Cell
Potent and specific antitumor effects of an anti-CD22-targeted cytotoxic ribonuclease: potential for the treatment of non-Hodgkin lymphoma.
Lymphoma, Non-Hodgkin
Anti-CD22 Onconase: preparation and characterization.
Antitumour Activity of the Ribonuclease Binase from Bacillus pumilus in the RLS40 Tumour Model Is Associated with the Reorganisation of the miRNA Network and Reversion of Cancer-Related Cascades to Normal Functioning.
Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells.
Melanoma
Antitumor activity and other biological actions of oligomers of ribonuclease A.
Cationic poly(amidoamine) promotes cytosolic delivery of bovine RNase A in melanoma cells, while maintaining its cellular toxicity.
Chromosomal assignment of three human melanocyte-specific genes.
Effect of hyaluronidase and PEG chain conjugation on the biologic and antitumor activity of RNase A.
Effect of Ribonuclease A and Deoxyribonuclease I on Immunostaining of Ki-67 in Cultured Melanoma Cells.
mPEG-PAMAM-G4 nucleic acid nanocomplexes: enhanced stability, rnase protection, and activity of splice switching oligomer and poly I:C RNA.
PEG chains increase aspermatogenic and antitumor activity of RNase A and BS-RNase enzymes.
Polymer-conjugated bovine pancreatic and seminal ribonucleases inhibit growth of human tumors in nude mice.
Poly[N-(2-hydroxypropyl)methacrylamide] conjugates of bovine pancreatic ribonuclease (RNase A) inhibit growth of human melanoma in nude mice.
Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells.
Melanoma, Amelanotic
Some biological actions of PEG-conjugated RNase A oligomers.
Mesothelioma
Three-state thermal unfolding of onconase.
Mesothelioma, Malignant
Cytotoxicity of bovine seminal ribonuclease: monomer versus dimer.
Neoplasm Metastasis
Antitumour Activity of the Ribonuclease Binase from Bacillus pumilus in the RLS40 Tumour Model Is Associated with the Reorganisation of the miRNA Network and Reversion of Cancer-Related Cascades to Normal Functioning.
Dual Targeting of Cancer Cells with DARPin-Based Toxins for Overcoming Tumor Escape.
Inhibition of metastasis development by daily administration of ultralow doses of RNase A and DNase I.
Ribonuclease binase decreases destructive changes of the liver and restores its regeneration potential in mouse lung carcinoma model.
Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells.
The systemic tumor response to RNase A treatment affects the expression of genes involved in maintaining cell malignancy.
Tumoricidal Activity of RNase A and DNase I.
Neoplasms
"Zero-length" dimers of ribonuclease A: further characterization and no evidence of cytotoxicity.
A ribonuclease A variant with low catalytic activity but high cytotoxicity.
A synapomorphic disulfide bond is critical for the conformational stability and cytotoxicity of an amphibian ribonuclease.
Analysis of ribonuclease activity in sub-nanoliter droplets by label-free fluorescence measurements.
Angiogenin promotes colorectal cancer metastasis via tiRNA production.
Angiogenin promotes tumoral growth and angiogenesis by regulating matrix metallopeptidase-2 expression via the ERK1/2 pathway.
Antibody fusion proteins with human ribonucleases 1 to 8.
Antitumor activity and toxicity of anti-HER2 immunoRNase scFv 4D5-dibarnase in mice bearing human breast cancer xenografts.
Antitumor Macrophage Response to Bacillus pumilus Ribonuclease (Binase).
Antitumour Activity of the Ribonuclease Binase from Bacillus pumilus in the RLS40 Tumour Model Is Associated with the Reorganisation of the miRNA Network and Reversion of Cancer-Related Cascades to Normal Functioning.
Attempts to Detect Agrobacterium tumefaciens DNA in Crown-Gall Tumor Tissue.
Bacillus intermedius ribonuclease (BINASE) induces apoptosis in human ovarian cancer cells.
Barnase as a new therapeutic agent triggering apoptosis in human cancer cells.
Binase induces apoptosis of transformed myeloid cells and does not induce T-cell immune response.
Bovine seminal ribonuclease triggers Beclin1-mediated autophagic cell death in pancreatic cancer cells.
Changes of telomerase and telomere lengths in paired normal and cancer tissues of breast.
Chaperonin-Dendrimer Conjugates for siRNA Delivery.
Charge designable and tunable GFP as a target pH-responsive carrier for intracellular functional protein delivery and tracing.
Conformational stability is a determinant of ribonuclease A cytotoxicity.
Contribution of active-site residues to the function of onconase, a ribonuclease with antitumoral activity.
Crystal structure of human angiogenin with an engineered loop exhibits conformational flexibility at the functional regions of the molecule.
Cytoplasmic localization of transcripts of a complex G+C-rich crab satellite DNA.
Cytosolic Delivery of Proteins Using Amphiphilic Polymers with 2-Pyridinecarboxaldehyde Groups for Site-Selective Attachment.
Cytotoxic ribonuclease chimeras. Targeted tumoricidal activity in vitro and in vivo.
Cytotoxicity of bovine seminal ribonuclease: monomer versus dimer.
Detection of high incidence of K-ras oncogenes during human colon tumorigenesis.
Developing chemically modified redox-responsive proteins as smart therapeutics.
Differential expression in glioblastoma multiforme and cerebral hemangioblastoma of cytoplasmic proteins that bind two different domains within the 3'-untranslated region of the human glucose transporter 1 (GLUT1) messenger RNA.
Disruption of shape-complementarity markers to create cytotoxic variants of ribonuclease A.
DNA ploidy and S-phase fraction analysis in peritoneal carcinomatosis from ovarian cancer: correlation with clinical pathological factors and response to chemotherapy.
Dual Targeting of Cancer Cells with DARPin-Based Toxins for Overcoming Tumor Escape.
Effect of the replacement of aspartic acid/glutamic acid residues with asparagine/glutamine residues in RNase He1 from Hericium erinaceus on inhibition of human leukemia cell line proliferation.
Effect of wheat leaf ribonuclease on tumor cells and tissues.
Effective expression and purification of recombinant onconase, an antitumor protein.
Efficient Intracellular Delivery of RNase A Using DNA Origami Carriers.
Evaluation of interstitial protein delivery in multicellular layers model.
Fluorescence assay for the binding of ribonuclease A to the ribonuclease inhibitor protein.
G1 arrest of U937 cells by onconase is associated with suppression of cyclin D3 expression, induction of p16INK4A, p21WAF1/CIP1 and p27KIP and decreased pRb phosphorylation.
Gene amplification of ESR1 in breast cancers-fact or fiction? A fluorescence in situ hybridization and multiplex ligation-dependent probe amplification study.
Hierarchical Nanoassemblies-Assisted Combinational Delivery of Cytotoxic Protein and Antibiotic for Cancer Treatment.
Homogeneous Electrochemiluminescence Biosensor for the Detection of RNase A Activity and Its Inhibitor.
Hyaluronic acid modification of RNase A and its intracellular delivery using lipid-like nanoparticles.
In situ hybridization analysis of chromogranin A and B mRNAs in neuroendocrine tumors with digoxigenin-labeled oligonucleotide probe cocktails.
Inclusion of a Furin Cleavage Site Enhances Antitumor Efficacy against Colorectal Cancer Cells of Ribotoxin ?-Sarcin- or RNase T1-Based Immunotoxins.
Inhibition of metastasis development by daily administration of ultralow doses of RNase A and DNase I.
Interaction of ribonuclease A with estrogen receptor from rat mammary tumor MTW9.
Interferon-gamma activates the cleavage of double-stranded RNA by bovine seminal ribonuclease.
Internalization of Bacillus intermedius ribonuclease (BINASE) induces human alveolar adenocarcinoma cell death.
KFERQ sequence in ribonuclease A-mediated cytotoxicity.
Landes Highlights.
Langmuir-Blodgett (LB)-based Nanobiocrystallography at the Frontiers of Cancer Proteomics.
Mesoporous polydopamine with built-in plasmonic core: Traceable and NIR triggered delivery of functional proteins.
MicroRNA drop in the bloodstream and microRNA boost in the tumour caused by treatment with ribonuclease A leads to an attenuation of tumour malignancy.
Modelling of electrokinetic phenomena for capture of PEGylated ribonuclease A in a microdevice with insulating structures.
Morpholino, Piperidino, and Pyrrolidino Derivatives of Pyrimidine Nucleosides as Inhibitors of Ribonuclease A: Synthesis, Biochemical, and Crystallographic Evaluation (#) (,) (dagger).
Mutational analysis of the extracellular Ca(2+)-sensing receptor gene in human parathyroid tumors.
Nano-Scaled Zeolitic Imidazole Framework-8 as an Efficient Carrier for the Intracellular Delivery of RNase A in Cancer Treatment.
Nanoscale ATP-Responsive Zeolitic Imidazole Framework-90 as a General Platform for Cytosolic Protein Delivery and Genome Editing.
Noncytotoxic ribonuclease, RNase T1, induces tumor cell death via hemagglutinating virus of Japan envelope vector.
On the inhibition of tumor inception in the crown-gall disease with the use of ribonuclease A.
Onconase cytotoxicity relies on the distribution of its positive charge.
Onconase: an unusually stable protein.
PEGylated gold nanoparticles-ribonuclease induced oxidative stress and apoptosis in colorectal cancer cells.
pH-Reversible Cationic RNase A Conjugates for Enhanced Cellular Delivery and Tumor Cell Killing.
Polymer-conjugated bovine pancreatic and seminal ribonucleases inhibit growth of human tumors in nude mice.
Poly[N-(2-hydroxypropyl)methacrylamide] conjugates of bovine pancreatic ribonuclease (RNase A) inhibit growth of human melanoma in nude mice.
Preparation, structural analysis and bioactivity of ribonuclease A-albumin conjugate: tetra-conjugation or PEG as the linker.
Production of Viral Vectors with Suicide Genes by Utilizing the Intron-Splicing Mechanism of Insect Cells.
Protein@Inorganic Nanodumpling System for High-Loading Protein Delivery with Activatable Fluorescence and Magnetic Resonance Bimodal Imaging Capabilities.
Recent Trends in the Design, Synthesis and Biological Exploration of ?-Lactams.
Redox-Responsive Polymeric Nanocomplex for Delivery of Cytotoxic Protein and Chemotherapeutics.
Residues involved in the catalysis, base specificity, and cytotoxicity of ribonuclease from Rana catesbeiana based upon mutagenesis and X-ray crystallography.
Ribonuclease activity of sialic acid-binding lectin from Rana catesbeiana eggs.
Ribonuclease binase decreases destructive changes of the liver and restores its regeneration potential in mouse lung carcinoma model.
Ribonuclease binase inhibits primary tumor growth and metastases via apoptosis induction in tumor cells.
Ribonuclease inhibitor as an intracellular sentry.
Sensitive Detection of RNase A Activity and Collaborative Drug Screening Based on rGO and Fluorescence Probe.
Site-specific RNase A activity was dramatically reduced in serum from multiple types of cancer patients.
Structural and functional implications of positive selection at the primate angiogenin gene.
Structure of endogenous retroviruses expressed in radiation-induced and spontaneous murine bone tumours.
The Cytotoxicity of RNase-Derived Peptides.
The importance of dynamic effects on the enzyme activity: X-ray structure and molecular dynamics of onconase mutants.
The inhibition of human tumor cell proliferation by RNase Pol, a member of the RNase T1 family, from Pleurotus ostreatus.
The Native Monomer of Bacillus Pumilus Ribonuclease Does Not Exist Extracellularly.
The systemic tumor response to RNase A treatment affects the expression of genes involved in maintaining cell malignancy.
Toward Artificial Immunotoxins: Traceless Reversible Conjugation of RNase A with Receptor Targeting and Endosomal Escape Domains.
Tumoricidal Activity of RNase A and DNase I.
X-Ray Crystallographic Structure of Hericium erinaceus Ribonuclease, RNase He1 in Complex with Zinc.
X-ray crystallographic structure of RNase Po1 that exhibits anti-tumor activity.
X-ray structure of two crystalline forms of a streptomycete ribonuclease with cytotoxic activity.
[Bacillus pumilus Ribonuclease Inhibits Migration of Human Duodenum Adenocarcinoma HuTu 80 Cells].
[Binase penetration into alveolar epithelial cells does not induce cell death].
[Effect of Bacillus pumilus ribonuclease on the paramagnetic centers of microbial cells].
[Exogenous Bacillus pumilus RNase (binase) suppresses the reproduction of reovirus serotype 1].
[Induction of apoptosis of tumor cells by binase]
[Ribonuclease binase induces death in T-cell acute lymphoblastic leukemia cells by apoptosis].
[Targeted Delivery of Quantum Dots to HER2-Expressing Tumor Using Recombinant Antibodies].
Neuroblastoma
Polymer-conjugated bovine pancreatic and seminal ribonucleases inhibit growth of human tumors in nude mice.
The inhibition of human tumor cell proliferation by RNase Pol, a member of the RNase T1 family, from Pleurotus ostreatus.
Neurodegenerative Diseases
A new role for angiogenin in neurite growth and pathfinding: implications for amyotrophic lateral sclerosis.
Structural basis of substrate specificity in porcine RNase 4.
Obesity
Subcutaneous or visceral adipose tissue expression of the PPARgamma gene is not altered in the fatty (fa/fa) Zucker rat.
Osteogenesis Imperfecta
A single amino acid deletion in the alpha 2(I) chain of type I collagen produces osteogenesis imperfecta type III.
Ovarian Neoplasms
Bacillus intermedius ribonuclease (BINASE) induces apoptosis in human ovarian cancer cells.
Plasma ribonuclease: a marker for the detection of ovarian cancer.
Papilloma
Binase treatment increases interferon sensitivity and apoptosis in SiHa cervical carcinoma cells by downregulating E6 and E7 human papilloma virus oncoproteins.
Parkinson Disease
Structural and molecular insights into the mechanism of action of human angiogenin-ALS variants in neurons.
Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis.
Pre-Eclampsia
Placental angiogenin inhibitor (ribonuclease inhibitor), a novel gene in pre-eclampsia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Ribonuclease binase induces death in T-cell acute lymphoblastic leukemia cells by apoptosis].
Rhinitis
Picornavirus RNA is protected from cleavage by ribonuclease during virion uncoating and transfer across cellular and model membranes.
ribonuclease e deficiency
Nutrient Dependence of RNase E Essentiality in Escherichia coli.
Sarcoma
Low frequency of (5'-3') -C-G- connection in 70S RNA from simian sarcoma virus.
Sarcoma, Avian
Bacillus intermedius ribonuclease as inhibitor of cell proliferation and membrane current.
Genetic structure and transforming sequence of avian sarcoma virus UR2.
Genetic variation and host markers in the src gene of recovered avian sarcoma viruses.
Terminally repeated sequences in the avian sarcoma virus RNA genome.
Scrapie
Effects of different methods of purification on aggregation of scrapie infectivity.
Inactivation of the scrapie agent by pronase.
Reduction of prion infectivity and levels of scrapie prion protein by lithium aluminum hydride: implications for RNA in prion diseases.
Starvation
A novel secreted ribonuclease from Bacillus intermedius: gene structure and regulatory control.
Activation of a selective pathway of lysosomal proteolysis in rat liver by prolonged starvation.
Altered degradation of proteins microinjected into senescent human fibroblasts.
Barnase and Binase: Twins with Distinct Fates.
Protein NO52--a constitutive nucleolar component sharing high sequence homologies to protein NO66.
Stomach Neoplasms
HER2 monoclonal antibody conjugated RNase-A-associated CdTe quantum dots for targeted imaging and therapy of gastric cancer.
Identification of genes differentially expressed between gastric cancers and normal gastric mucosa with cDNA microarrays.
Subacute Sclerosing Panencephalitis
Common buffers, media, and stock solutions.
Thrombosis
My 65 years in protein chemistry.
Thymoma
Structure of retroviral RNAs produced by cell lines derived from spontaneous lymphomas of AKR mice.
Thyroid Neoplasms
Analysis of ribonuclease activity in sub-nanoliter droplets by label-free fluorescence measurements.
Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis.
Tuberculosis
Liquid chromatography-mass spectrometry structural characterization of neo glycoproteins aiding the rational design and synthesis of a novel glycovaccine for protection against tuberculosis.
Quaternary structure and biochemical properties of mycobacterial RNase E/G.
The first small-molecule inhibitors of members of the ribonuclease E family.
Urinary Tract Infections
The Responses of the Ribonuclease A Superfamily to Urinary Tract Infection.
Vesicular Stomatitis
Assignment of the large oligonucleotides of vesicular stomatitis virus to the N, NS, M, G, and L genes and oligonucleotide gene ordering within the L gene.
Bovine coronavirus genome.
Comparison of ribonucleotide sequences from the genome of vesicular stomatitis virus and two of its defective interfering particles.
Sequential synthesis of 5'-proximal vesicular stomatitis virus mRNA sequences.
Virus Diseases
Baculovirus-mediated gene transfer into mammalian cells.
Herpes Simplex Virus 1 Tegument Protein UL41 Counteracts IFIT3 Antiviral Innate Immunity.