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Information on EC 4.6.1.17 - cyclic pyranopterin monophosphate synthase

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IUBMB Comments
The enzyme catalyses an early step in the biosynthesis of the molybdenum cofactor (MoCo). In bacteria and plants the reaction is catalysed by MoaC and Cnx3, respectively. In mammals the reaction is catalysed by the MOCS1B domain of the bifuctional MOCS1 protein, which also catalyses EC 4.1.99.22, GTP 3',8-cyclase.
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The expected taxonomic range for this enzyme is: Bacteria, Eukaryota, Archaea
Synonyms
moac2, st0472, molybdenum cofactor biosynthesis protein c, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate
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GTP = cyclic pyranopterin phosphate + diphosphate
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PATHWAY SOURCE
PATHWAYS
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