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Information on EC 4.4.1.21 - S-ribosylhomocysteine lyase

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IUBMB Comments
Contains Fe2+. The 4,5-dihydroxypentan-2,3-dione formed spontaneously cyclizes and combines with borate to form an autoinducer (AI-2) in the bacterial quorum-sensing mechanism, which is used by many bacteria to control gene expression in response to cell density .
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The enzyme appears in viruses and cellular organisms
Synonyms
luxs protein, ai-2 synthase, s-ribosylhomocysteinase, autoinducer-2 synthase, s-ribosylhomocysteinelyase, s-ribosyl homocysteinase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = L-homocysteine + (4S)-4,5-dihydroxypentan-2,3-dione
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