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Information on EC 4.3.2.4 - purine imidazole-ring cyclase

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EC Tree
     4 Lyases
         4.3 Carbon-nitrogen lyases
             4.3.2 Amidine-lyases
                4.3.2.4 purine imidazole-ring cyclase
IUBMB Comments
Also acts on 2,6-diamino-5-formamido-3,4-dihydro-4-oxopyrimidine residues. Brings about the reclosure of the imidazole rings of purine residues damaged by gamma-rays.
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The expected taxonomic range for this enzyme is: Eukaryota, Bacteria
Synonyms
cyclase, purine imidazole ring, PurIR cyclase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O
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