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Disease on EC 4.1.99.3 - deoxyribodipyrimidine photo-lyase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Acquired Immunodeficiency Syndrome
A novel role for DNA photolyase: binding to DNA damaged by drugs is associated with enhanced cytotoxicity in Saccharomyces cerevisiae.
Dynamics of RecA filaments on single-stranded DNA.
The other function of DNA photolyase: stimulation of excision repair of chemical damage to DNA.
Adenocarcinoma
Dietary supplementation with silymarin inhibits 3,2'-dimethyl-4-aminobiphenyl-induced prostate carcinogenesis in male F344 rats.
Adenoma
Evaluation of apoptosis as a factor affecting the growth of non-polypoid colorectal adenomas.
Adenoviridae Infections
Release of viruses and viral DNA from nucleus to cytoplasm of HeLa cells at late stages of productive adenovirus infection as revealed by electron microscope in situ hybridization.
African Swine Fever
Interactions of the DNA polymerase X from African Swine Fever Virus with the ssDNA. Properties of the total DNA-binding site and the strong DNA-binding subsite.
Kinetic mechanism of the ssDNA recognition by the polymerase X from African Swine Fever Virus. Dynamics and energetics of intermediate formations.
Ameloblastoma
Immunohistochemical analysis of apoptosis-related factors (Fas, Fas ligand, caspase-3 and single-stranded DNA) in ameloblastomas.
Anemia
Beak and feather disease virus and porcine circovirus genomes: intermediates between the geminiviruses and plant circoviruses.
Anemia, Hemolytic
Single?strained DNA aptamers mask RhD antigenic epitopes on human RhD+ red blood cells to escape alloanti?RhD immunological recognition.
Anthrax
Gel green fluorescence ssDNA aptasensor based on carbon nanotubes for detection of anthrax protective antigen.
Inhibition of anthrax lethal factor by ssDNA aptamers.
Nano aptasensor for protective antigen toxin of anthrax.
Screening and characterization of high-affinity ssDNA aptamers against anthrax protective antigen.
Synergic TiO2 photocatalysis and guanine photoreduction for silver deposition amplification: an ultrasensitive and high-throughput visualized colorimetric analysis strategy for anthrax DNAs in blood using a wettable microwells array.
Arthritis
Common serological features in rheumatoid arthritis and yersinia arthritis. Demonstration of rheumatoid factors and antibodies against ssDNA and Yersinia enterocolitica Lipopolysaccharide by ELISA.
New approaches to targeting arthritis with radiopharmaceuticals.
Arthritis, Juvenile
Antibody reactivity against single stranded DNA of various species in normal children and in children with diffuse connective tissue diseases.
Autoantibody profiles in juvenile arthritis.
Arthritis, Rheumatoid
A ssDNA Aptamer That Blocks the Function of the Anti-FLAG M2 Antibody.
Common serological features in rheumatoid arthritis and yersinia arthritis. Demonstration of rheumatoid factors and antibodies against ssDNA and Yersinia enterocolitica Lipopolysaccharide by ELISA.
Cross-reactive rheumatoid factors in rheumatoid arthritis with extra-articular disease.
Ataxia Telangiectasia
DNA End Resection: Facts and Mechanisms.
RPA and POT1: Friends or foes at telomeres?
TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA.
Autoimmune Diseases
A comparison of three methods for production of human hybridomas secreting autoantibodies.
A ssDNA Aptamer That Blocks the Function of the Anti-FLAG M2 Antibody.
Characteristics of antibodies adsorbed on the DNA immunoadsorbent, agarose poly-L-lysine-DNA.
Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease.
Brain Diseases
Evidence that homologous ssDNA is present in scrapie, Creutzfeldt-Jakob disease, and bovine spongiform encephalopathy.
Brain Injuries
Single-stranded DNA as an immunohistochemical marker of neuronal damage in human brain: an analysis of autopsy material with regard to the cause of death.
Brain Ischemia
Alterations of oxidative stress markers and apoptosis markers in the striatum after transient focal cerebral ischemia in rats.
Breast Neoplasms
A label-free genosensor for BRCA1 related sequence based on impedance spectroscopy.
An Aptamer-Based Probe for Molecular Subtyping of Breast Cancer.
Correlation between ER, PR, HER-2, Bcl-2, p53, proliferative and apoptotic indexes with HER-2 gene amplification and TOP2A gene amplification and deletion in four molecular subtypes of breast cancer.
Detection of novel infiltrating ductal carcinoma-associated BReast CAncer gene 2 mutations which alter the deoxyribonucleic acid-binding ability of BReast CAncer gene 2 protein.
Differentiating breast cancer molecular subtypes using a DNA aptamer selected against MCF-7 cells.
Expression of phosphodiesterase 6 (PDE6) in human breast cancer cells.
Identification of an aptamer targeting hnRNP A1 by tissue slide-based SELEX.
The importance of codon context for understanding the Ig-like somatic hypermutation strand-biased patterns in TP53 mutations in breast cancer.
Carcinogenesis
Powerful skin cancer protection by a CPD-photolyase transgene.
Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity.
Topical Application of Preparations Containing DNA Repair Enzymes Prevents Ultraviolet-Induced Telomere Shortening and c-FOS Proto-Oncogene Hyperexpression in Human Skin: An Experimental Pilot Study.
Carcinoma
Evolution of a gastric carcinoma cell-specific DNA aptamer by live cell-SELEX.
Prognostic significance of apoptotic cell death in bladder cancer: a tissue microarray study on 179 urothelial carcinomas from cystectomy specimens.
Carcinoma, Ductal
Identification of an aptamer targeting hnRNP A1 by tissue slide-based SELEX.
Carcinoma, Ehrlich Tumor
[Binding of SSB-protein from Ehrlich ascites carcinoma cells with DNA and polyribonucleotides]
[The effect of SSB-protein from Ehrlich ascites carcinoma cells on activity of various enzymes of DNA replication and repair]
Carcinoma, Hepatocellular
Alpha actin gene exist in an active structural configuration in the proliferating myoblasts as well as in differentiated myotubes of the L6 line.
Fluorescent quantum dot-labeled aptamer bioprobes specifically targeting mouse liver cancer cells.
Growth index, assessed with Ki-67 and ssDNA labeling; a significant prognosticator for patients undergoing curative resection for hepatocellular carcinoma.
Over expression of glutamate cysteine ligase increases cellular resistance to H2O2-induced DNA single-strand breaks.
Role of ssDNA as a Noninvasive Indicator for the Diagnosis and Prognosis of Hepatocellular Carcinoma: An Exploratory Study.
Screening and verification of ssDNA aptamers targeting human hepatocellular carcinoma.
Single-stranded DNA condensed with poly-L-lysine results in nanometric particles that are significantly smaller, more stable in physiological ionic strength fluids and afford higher efficiency of gene delivery than their double-stranded counterparts.
Carcinoma, Intraductal, Noninfiltrating
Immunohistochemical expression of uPA, PAI-1, cathepsin D and apoptotic cells in ductal carcinoma in situ of the breast.
Cardiomyopathy, Dilated
Non-specific autoantibodies in cardiomyopathies and myocardial infarction.
Cardiomyopathy, Hypertrophic
Non-specific autoantibodies in cardiomyopathies and myocardial infarction.
Cataract
Localization of cell apoptosis in the opaque portion of anterior polar cataract and anterior capsulotomy margin.
Cholesteatoma
Overexpression of ErbB-2 protein in human middle ear cholesteatomas.
Cholesteatoma, Middle Ear
Overexpression of ErbB-2 protein in human middle ear cholesteatomas.
Cluster Headache
The molecular clock gene cryptochrome 1 (CRY1) and its role in cluster headache.
Cockayne Syndrome
Fine-tuning of the replisome: Mcm10 regulates fork progression and regression.
Coinfection
Ecology and evolution of viruses infecting uncultivated SUP05 bacteria as revealed by single-cell- and meta-genomics.
Epidemiology and evolutionary analysis of Torque teno sus virus.
Colonic Neoplasms
Ortho-Stabilized (18) F-Azido Click Agents and their Application in PET Imaging with Single-Stranded DNA Aptamers.
Color Vision Defects
Mouse Models of Achromatopsia in Addressing Temporal "Point of No Return" in Gene-Therapy.
Colorectal Neoplasms
Cryptochrome 1 overexpression correlates with tumor progression and poor prognosis in patients with colorectal cancer.
Detection of apoptotic cells in human colorectal cancer by two different in situ methods: antibody against single-stranded DNA and terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end-labeling (TUNEL) methods.
Coma
Formation of single-stranded DNA during DNA transformation of Neisseria gonorrhoeae.
Connective Tissue Diseases
Antibody reactivity against single stranded DNA of various species in normal children and in children with diffuse connective tissue diseases.
Evaluation of the simultaneous estimation of anti-dsDNA and anti-ssDNA antibodies for clinical purposes.
[Antinuclear antibody screening by an enzyme-linked immunosorbent assay using multiple nuclear antigens]
[What are IgG antibodies to single-stranded DNA measured by enzyme immunoassay--re-evaluation of their clinical significance]
COVID-19
Genetic Risk Factors for the Development of COVID-19 Coronavirus Infection.
Creutzfeldt-Jakob Syndrome
Evidence that homologous ssDNA is present in scrapie, Creutzfeldt-Jakob disease, and bovine spongiform encephalopathy.
Cystic Fibrosis
Biochip data normalization using multifunctional probes.
Cysts
Comparative Immunohistochemical Analyses on the Modes of Cell Death/Keratinization in Epidermal Cyst, Trichilemmal Cyst, and Pilomatricoma.
Decompression Sickness
Impediment of E. coli UvrD by DNA-destabilizing force reveals a strained-inchworm mechanism of DNA unwinding.
Dengue
Comparative clinical sample preparation of DNA and RNA viral nucleic acids for a commercial deep sequencing system (Illumina MiSeq(®)).
Dental Caries
Identification of ssDNA aptamers specific to clinical isolates of Streptococcus mutans strains with different cariogenicity.
deoxyribodipyrimidine photo-lyase deficiency
Active DNA photolyase encoded by a baculovirus from the insect Chrysodeixis chalcites.
Cloning and characterization of a class II DNA photolyase from Chlamydomonas.
Multiple initiation mechanisms adapt phage T4 DNA replication to physiological changes during T4's development.
Two new early bacteriophage T4 genes, repEA and repEB, that are important for DNA replication initiated from origin E.
Dermatomyositis
Antibody reactivity against single stranded DNA of various species in normal children and in children with diffuse connective tissue diseases.
Diabetes Mellitus, Type 2
ssDNA Aptamer-Based Surface Plasmon Resonance Biosensor for the Detection of Retinol Binding Protein 4 for the Early Diagnosis of Type 2 Diabetes.
Distemper
Comparative clinical sample preparation of DNA and RNA viral nucleic acids for a commercial deep sequencing system (Illumina MiSeq(®)).
DNA Repair-Deficiency Disorders
PARPi Triggers the STING-Dependent Immune Response and Enhances the Therapeutic Efficacy of Immune Checkpoint Blockade Independent of BRCAness.
UV radiation-sensitive norin 1 rice contains defective cyclobutane pyrimidine dimer photolyase.
dna topoisomerase (atp-hydrolysing) deficiency
Double-strand break repair and genetic recombination in topoisomerase and primase mutants of bacteriophage T4.
Down Syndrome
Single-Stranded DNA Library Preparation Preferentially Enriches Short Maternal DNA in Maternal Plasma.
Encephalopathy, Bovine Spongiform
Evidence that homologous ssDNA is present in scrapie, Creutzfeldt-Jakob disease, and bovine spongiform encephalopathy.
Eosinophilia
Macrophages are involved in hexachlorobenzene-induced adverse immune effects.
Erythema
A new quantitative PCR for human parvovirus B19 genotypes.
Familial Mediterranean Fever
Determination of autoantibodies in patients with familial Mediterranean fever and their first degree relatives.
Fanconi Anemia
HPV-16 E7 reveals a link between DNA replication stress, fanconi anemia D2 protein, and alternative lengthening of telomere-associated promyelocytic leukemia bodies.
Fetal Death
A new quantitative PCR for human parvovirus B19 genotypes.
Fowlpox
Fowlpox virus encodes a novel DNA repair enzyme, CPD-photolyase, that restores infectivity of UV light-damaged virus.
The DNA repair enzyme, CPD-photolyase restores the infectivity of UV-damaged fowlpox virus isolated from infected scabs of chickens.
Gastroenteritis
A diverse group of small circular ssDNA viral genomes in human and non-human primate stools.
Glioblastoma
Target-specific delivery of doxorubicin to human glioblastoma cell line via ssDNA aptamer.
Glioma
Retinoic acid?incorporated glycol chitosan nanoparticles inhibit the expression of Ezh2 in U118 and U138 human glioma cells.
The anti-tumor effects of calorie restriction are correlated with reduced oxidative stress in ENU-induced gliomas.
Glomerulonephritis
A murine nephritogenic monoclonal antibody binds to both single-stranded deoxyribonucleic acid and glomerulus.
Histones have high affinity for the glomerular basement membrane. Relevance for immune complex formation in lupus nephritis.
Specificity and immunochemical properties of antibodies to bacterial DNA.
Glomerulonephritis, IGA
IgA affinity to ssDNA or endothelial cells and its deposition in glomerular capillary walls in IgA nephropathy.
Glucose Intolerance
Cryptochromes mediate rhythmic repression of the glucocorticoid receptor.
Graves Disease
Antideoxyribonucleic acid antibodies in Graves' disease.
Guillain-Barre Syndrome
Autoantibodies to phospholipids and brain extract in patients with the Guillain-Barre syndrome: cross-reactive or pathogenic?
Hashimoto Disease
Probing the normal and autoimmune B cell repertoire with Epstein-Barr virus. Frequency of B cells producing monoreactive high affinity autoantibodies in patients with Hashimoto's disease and systemic lupus erythematosus.
Heart Failure
Dysregulated IER3 Expression is Associated with Enhanced Apoptosis in Titin-Based Dilated Cardiomyopathy.
Hepatitis B
Bovine thrombin enhances the efficiency and specificity of polymerase chain reaction.
Electrochemical detection of hepatitis B and papilloma virus DNAs using SWCNT array coated with gold nanoparticles.
Reprogrammable Gel Electrophoresis Detection Assay Using CRISPR-Cas12a and Hybridization Chain Reaction.
Rolling cycle amplification based single-color quantum dots-ruthenium complex assembling dyads for homogeneous and highly selective detection of DNA.
Sensitive DNA biosensor improved by Luteolin copper(II) as indicator based on silver nanoparticles and carbon nanotubes modified electrode.
Silica nanoparticles coated by poly(acrylic acid) brushes via host-guest interactions for detecting DNA sequence of Hepatitis B virus.
Snow goose hepatitis B virus (SGHBV) envelope and capsid proteins independently contribute to the ability of SGHBV to package capsids containing single-stranded DNA in virions.
Hepatitis C
CS-SELEX generates high-affinity ssDNA aptamers as molecular probes for hepatitis C virus envelope glycoprotein E2.
Effects of free patchy ends in ssDNA and dsDNA on gold nanoparticles in a colorimetric gene sensor for Hepatitis C virus RNA.
Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe.
Microwave-accelerated surface plasmon-coupled directional luminescence 2: a platform technology for ultra fast and sensitive target DNA detection in whole blood.
Specific ssDNA concentration in liver tissue as an index of apoptosis in hepatitis C virus-infected patients.
Hepatitis, Chronic
Role of ssDNA as a Noninvasive Indicator for the Diagnosis and Prognosis of Hepatocellular Carcinoma: An Exploratory Study.
Herpes Simplex
A mutation in the human herpes simplex virus type 1 UL52 zinc finger motif results in defective primase activity but can recruit viral polymerase and support viral replication efficiently.
A paramagnetic-reporter two-particle system for amplification-free detection of DNA in serum.
An intertypic herpes simplex virus helicase-primase complex associated with a defect in neurovirulence has reduced primase activity.
Association of DNA helicase and primase activities with a subassembly of the herpes simplex virus 1 helicase-primase composed of the UL5 and UL52 gene products.
Equilibrium binding of single-stranded DNA with herpes simplex virus type I-coded single-stranded DNA-binding protein, ICP8.
Helicase primase: targeting the Achilles heel of herpes simplex viruses.
Helicase-primase complex of herpes simplex virus type 1: a mutation in the UL52 subunit abolishes primase activity.
Herpes simplex virus 1 primase employs watson-crick hydrogen bonding to identify cognate nucleoside triphosphates.
Herpes simplex virus type 1 helicase-primase: DNA binding and consequent protein oligomerization and primase activation.
Herpes Simplex Virus-1 DNA Primase: A Remarkably Inaccurate yet Selective Polymerase.
Herpes simplex virus-1 primase: a polymerase with extraordinarily low fidelity.
Identification of conserved amino acids in the Herpes simplex virus type 1 UL8 protein required for DNA synthesis and UL52 primase interaction in the virus replisome.
Identification of the primase active site of the herpes simplex virus type 1 helicase-primase.
Interactions of a subassembly of the herpes simplex virus type 1 helicase-primase with DNA.
Key role of template sequence for primer synthesis by the herpes simplex virus 1 helicase-primase.
New antiviral drugs that target herpesvirus helicase primase enzymes.
Recruitment of polymerase to herpes simplex virus type 1 replication foci in cells expressing mutant primase (UL52) proteins.
RNA binding and R-loop formation by the herpes simplex virus type-1 single-stranded DNA-binding protein (ICP8).
The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1.
trans-acting requirements for replication of Epstein-Barr virus ori-Lyt.
UL52 primase interactions in the herpes simplex virus 1 helicase-primase are affected by antiviral compounds and mutations causing drug resistance.
HIV Infections
Concentrations of ssDNA in liver tissue and its correlation with sFas and sFasL in serum of patients infected with HBV, HCV, HCV and HIV.
Hodgkin Disease
Autoantibodies in the sera of patients with lymphoma.
Biostable ssDNA aptamers specific for Hodgkin lymphoma.
Hyperaldosteronism
Development of monoclonal antibodies against the human 3?-hydroxysteroid dehydrogenase/isomerase isozymes.
Hypergammaglobulinemia
A comparison of serologic reactivity among SLE patients with or without anti-Ro (SS-A) antibodies.
Induction of lupus-related specific autoantibodies by non-specific inflammation caused by an intraperitoneal injection of n-hexadecane in BALB/c mice.
Hypersensitivity
Ca2+-Stimulated AMPK-Dependent Phosphorylation of Exo1 Protects Stressed Replication Forks from Aberrant Resection.
Replication Gaps Underlie BRCA Deficiency and Therapy Response.
Hypertension
Development of monoclonal antibodies against the human 3?-hydroxysteroid dehydrogenase/isomerase isozymes.
Infections
A meta-analysis reveals the commonalities and differences in Arabidopsis thaliana response to different viral pathogens.
A novel primase-free form of murine DNA polymerase alpha induced by infection with minute virus of mice.
A phage single-stranded DNA (ssDNA) binding protein complements ssDNA accumulation of a geminivirus and interferes with viral movement.
Anti-ssDNA and antinuclear antibodies in human malaria.
DANCING WITH CHEMICAL FORMULAE OF ANTIVIRALS: A PANORAMIC VIEW (part 2).
Designing anti-influenza aptamers: novel quantitative structure activity relationship approach gives insights into aptamer-virus interaction.
Double-Stranded RNA Is Detected by Immunofluorescence Analysis in RNA and DNA Virus Infections, Including Those by Negative-Stranded RNA Viruses.
Emerging therapies for herpes viral infections (types 1 - 8).
Genetic Risk Factors for the Development of COVID-19 Coronavirus Infection.
In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins.
Induction of ssDNA-binding autoantibody secreting B cell immunity during murine malaria infection is a critical part of the protective immune responses.
Innate Inflammatory Responses of Pediatric Cystic Fibrosis Airway Epithelial Cells: Effects of Non-Viral and Viral Stimulation.
Insect Transmission of Plant Single-Stranded DNA Viruses.
Isolation and characterization of a new class of DNA aptamers specific binding to Singapore grouper iridovirus (SGIV) with antiviral activities.
Manipulation of the Plant Host by the Geminivirus AC2/C2 Protein, a Central Player in the Infection Cycle.
New bacteriophages that infect the phytopathogen Ralstonia solanacearum.
Plasmid pFCE4: a new system of Escherichia coli expression-modification vectors.
Pseudomonas aeruginosa-induced human mast cell apoptosis is associated with up-regulation of endogenous Bcl-xS and down-regulation of Bcl-xL.
Quantitative real-time PCR for titration of infectious recombinant AAV-2 particles.
Recent Progress in the Identification of Aptamers Against Bacterial Origins and Their Diagnostic Applications.
Secretion of Chromosomal DNA by the Neisseria gonorrhoeae Type IV Secretion System.
Single-stranded DNA binding protein encoded by the filamentous bacteriophage M13: structural and functional characteristics.
Specific growth rate and multiplicity of infection affect high-cell-density fermentation with bacteriophage M13 for ssDNA production.
SspABCD-SspFGH Constitutes a New Type of DNA Phosphorothioate-Based Bacterial Defense System.
The "Neglected Viruses" of Taihu: Abundant Transcripts for Viruses Infecting Eukaryotes and Their Potential Role in Phytoplankton Succession.
The capsid protein of tomato yellow leaf curl virus binds cooperatively to single-stranded DNA.
The first strand transfer reaction of HIV-1 reverse transcription is more efficient in infected cells than in cell-free natural endogenous reverse transcription reactions.
Trans-sialidase recombinant protein mixed with CpG motif-containing oligodeoxynucleotide induces protective mucosal and systemic trypanosoma cruzi immunity involving CD8+ CTL and B cell-mediated cross-priming.
Typhoid toxin exhausts the RPA response to DNA replication stress driving senescence and Salmonella infection.
Yellow mosaic symptom caused by the nuclear shuttle protein gene of mungbean yellow mosaic virus is associated with single-stranded DNA accumulation and mesophyll spread of the virus.
Influenza in Birds
Development of ssDNA Aptamers for Diagnosis and Inhibition of the Highly Pathogenic Avian Influenza Virus Subtype H5N1.
Hydrogel based QCM aptasensor for detection of avian influenza virus.
Influenza, Human
A DNA Aptamer Against Influenza A Virus: An Effective Inhibitor to the Hemagglutinin-Glycan Interactions.
B lymphocyte hyperactivity in families of patients with systemic lupus erythematosus.
Combining RNA-DNA swapping and quantitative polymerase chain reaction for the detection of influenza A nucleoprotein.
DANCING WITH CHEMICAL FORMULAE OF ANTIVIRALS: A PANORAMIC VIEW (part 2).
Designing anti-influenza aptamers: novel quantitative structure activity relationship approach gives insights into aptamer-virus interaction.
Detection of genetic markers related to high pathogenicity in influenza by SERS.
Electrochemical DNA Biosensor Based on a Tetrahedral Nanostructure Probe for the Detection of Avian Influenza A (H7N9) Virus.
Identification of virulence determinants in influenza viruses.
Insulin Resistance
Correlation between vitamin D levels and apoptosis in geriatric patients infected with hepatitis C virus genotype 4.
Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance.
Ischemic Stroke
Particulate Air Pollution, Clock Gene Methylation, and Stroke: Effects on Stroke Severity and Disability.
Keratosis, Actinic
A 9-month, randomized, assessor-blinded parallel-group study to evaluate clinical effects of a film-forming medical devices containing photolyase and sun-filters in the treatment of cancerization field in comparison with sunscreen in patients after successful PDT for Actinic Keratosis.
Efficacy of a photolyase-based device in the treatment of cancerization field in patients with actinic keratosis and non-melanoma skin cancer.
Review of Clinical Evidence over 10 Years on Prevention and Treatment of a Film-Forming Medical Device Containing Photolyase in the Management of Field Cancerization in Actinic Keratosis.
Kidney Diseases
A monoclonal DNA-binding autoantibody causes a deterioration in renal function in MRL mice with lupus disease.
Leukemia
Genetic studies in NZB mice. VI. Association of autoimmune traits in recombinant inbred lines.
Murine APOBEC1 is a powerful mutator of retroviral and cellular RNA in vitro and in vivo.
Nontemplated base addition by HIV-1 RT can induce nonspecific strand transfer in vitro.
The 10-23 DNA enzyme generated by a novel expression vector mediate inhibition of taco expression in macrophage.
Leukemia, Lymphocytic, Chronic, B-Cell
Epigenetic silencing of the circadian clock gene CRY1 is associated with an indolent clinical course in chronic lymphocytic leukemia.
Leukemia, T-Cell
Nontemplated base addition by HIV-1 RT can induce nonspecific strand transfer in vitro.
Liver Cirrhosis, Biliary
Acetylcholine receptor antibodies in primary biliary cirrhosis: characterization of antigen and idiotypic specificity.
Liver Diseases
Role of ssDNA as a Noninvasive Indicator for the Diagnosis and Prognosis of Hepatocellular Carcinoma: An Exploratory Study.
Liver Neoplasms, Experimental
Stimulation of calf thymus DNA polymerase alpha activity by nucleolar protein B23.
Lung Neoplasms
APOBEC1 cytosine deaminase activity on single-stranded DNA is suppressed by replication protein A.
Evaluation of inhibition of miRNA expression induced by anti-miRNA oligonucleotides.
Lupus Erythematosus, Discoid
Serologic and clinical features of patients with discoid lupus erythematosus: relationship of antibodies to single-stranded deoxyribonucleic acid and of other antinuclear antibody subsets to clinical manifestations.
Lupus Erythematosus, Systemic
A comparison of three methods for production of human hybridomas secreting autoantibodies.
A ssDNA Aptamer That Blocks the Function of the Anti-FLAG M2 Antibody.
Autoantibodies to phospholipids and brain extract in patients with the Guillain-Barre syndrome: cross-reactive or pathogenic?
Fixation of complement by anti-F(ab')2 antibodies or ssDNA when added to systemic lupus erythematosus sera.
High titers of antibodies to single-stranded DNA in linear scleroderma.
High-affinity antibodies to ssDNA are produced by CD-B cells in systemic lupus erythematosus patients.
Selective recognition of DNA antigenic determinants by murine monoclonal anti-DNA antibodies.
Serologic and clinical features of patients with discoid lupus erythematosus: relationship of antibodies to single-stranded deoxyribonucleic acid and of other antinuclear antibody subsets to clinical manifestations.
[Measurement of antibodies to double-stranded and single-stranded DNA using bacteriophage lambda DNA as the antigen--avidity of antibodies to DNA in patients with lupus nephritis]
[What are IgG antibodies to single-stranded DNA measured by enzyme immunoassay--re-evaluation of their clinical significance]
Lupus Nephritis
A monoclonal DNA-binding autoantibody causes a deterioration in renal function in MRL mice with lupus disease.
[Measurement of antibodies to double-stranded and single-stranded DNA using bacteriophage lambda DNA as the antigen--avidity of antibodies to DNA in patients with lupus nephritis]
Lymphadenitis
Apoptosis- and cell cycle-associated gene expression profiling of histiocytic necrotising lymphadenitis.
Lymphoma
Aptamer Internalization via Endocytosis Inducing S-Phase Arrest and Priming Maver-1 Lymphoma Cells for Cytarabine Chemotherapy.
CD30 aptamer-functionalized PEG-PLGA nanoparticles for the superior delivery of doxorubicin to anaplastic large cell lymphoma cells.
Immunohistochemical analysis of cleaved caspase-3 detects high level of apoptosis frequently in diffuse large B-cell lymphomas of the central nervous system.
Immunotherapy of CD30-expressing lymphoma using a highly stable ssDNA aptamer.
Nucleoprotein complexes released from lymphoma nuclei that contain the abl oncogene and RNA and DNA polymerase and RNA primase activities.
Lymphoma, Large-Cell, Anaplastic
CD30 aptamer-functionalized PEG-PLGA nanoparticles for the superior delivery of doxorubicin to anaplastic large cell lymphoma cells.
Lymphoma, Non-Hodgkin
Autoantibodies in the sera of patients with lymphoma.
Manifold expression of new cellular genes in human lymphoid neoplasia.
Malaria
Anti-ssDNA and antinuclear antibodies in human malaria.
Enhanced UV Resistance and Improved Killing of Malaria Mosquitoes by Photolyase Transgenic Entomopathogenic Fungi.
Induction of ssDNA-binding autoantibody secreting B cell immunity during murine malaria infection is a critical part of the protective immune responses.
Melanoma
A UVR-Induced G2-Phase Checkpoint Response to ssDNA Gaps Produced by Replication Fork Bypass of Unrepaired Lesions Is Defective in Melanoma.
The value of fluorimetry (Qubit) and spectrophotometry (NanoDrop) in the quantification of cell-free DNA (cfDNA) in malignant melanoma and prostate cancer patients.
Metrorrhagia
Optimization of an electrochemical DNA assay by using a 48-electrode array and redox amplification studies by means of scanning electrochemical microscopy.
Myasthenia Gravis
Acetylcholine receptor antibodies in primary biliary cirrhosis: characterization of antigen and idiotypic specificity.
Myocardial Infarction
Mitochondrial autophagy and cell survival is regulated by the circadian Clock gene in cardiac myocytes during ischemic stress.
Non-specific autoantibodies in cardiomyopathies and myocardial infarction.
Neoplasm Metastasis
Evading immune surveillance via tyrosine phosphorylation of nuclear PCNA.
Generating lung-metastatic osteosarcoma targeting aptamers for in vivo and clinical tissue imaging.
Neoplasm Micrometastasis
[Clinicopathological and biological features of micrometastasis in early gastric cancers]
Neoplasms
A 3D hydrogel based on chitosan and carbon dots for sensitive fluorescence detection of microRNA-21 in breast cancer cells.
A multiple aptasensor for ultrasensitive detection of miRNAs by using covalent-organic framework nanowire as platform and shell-encoded gold nanoparticles as signal labels.
A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1.
Advantages of Single-Stranded DNA Over Double-Stranded DNA Library Preparation for Capturing Cell-Free Tumor DNA in Plasma.
Anti-VCAM-1 and Anti-IL4R? Aptamer-Conjugated Super Paramagnetic Iron Oxide Nanoparticles for Enhanced Breast Cancer Diagnosis and Therapy.
APOBEC-induced mutations in human cancers are strongly enriched on the lagging DNA strand during replication.
APOBEC3 cytidine deaminases in double-strand DNA break repair and cancer promotion.
APOBEC3A and APOBEC3B Preferentially Deaminate the Lagging Strand Template during DNA Replication.
Aptamer-T Cell Targeted Therapy for Tumor Treatment Using Sugar Metabolism and Click Chemistry.
Avoidance of APOBEC3B-induced mutation by error-free lesion bypass.
Cancer-Specific Synthetic Lethality between ATR and CHK1 Kinase Activities.
Carbon nanotube decorated magnetic microspheres as an affinity matrix for biomolecules.
Cell cycle arrest triggered by conjugated eicosapentaenoic acid occurs through several mechanisms including G1 checkpoint activation by induced RPA and ATR expression.
Circadian molecular clocks and cancer.
Controlled-release system of single-stranded DNA triggered by the photothermal effect of gold nanorods and its in vivo application.
Correlation between ER, PR, HER-2, Bcl-2, p53, proliferative and apoptotic indexes with HER-2 gene amplification and TOP2A gene amplification and deletion in four molecular subtypes of breast cancer.
Correlation of enhanced cell turnover with prognosis of gastrointestinal stromal tumors of the stomach: relevance of cellularity and p27kip1.
Cry 1 Regulates the Clock Gene Network and Promotes Proliferation and Migration Via the Akt/P53/P21 Pathway in Human Osteosarcoma Cells.
Cryptochrome 1 overexpression correlates with tumor progression and poor prognosis in patients with colorectal cancer.
Decreased expression of the melatonin receptor 1 in human colorectal adenocarcinomas.
Derepression of co-silenced tumor suppressor genes by nanoparticle-loaded circular ssDNA reduces tumor malignancy.
Detection of apoptotic cells in human colorectal cancer by two different in situ methods: antibody against single-stranded DNA and terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end-labeling (TUNEL) methods.
Detection of novel infiltrating ductal carcinoma-associated BReast CAncer gene 2 mutations which alter the deoxyribonucleic acid-binding ability of BReast CAncer gene 2 protein.
Differences in clinicopathological findings, cell kinetics and p53 expression between early gastric cancers with and without Helicobacter pylori infection.
Distinct but Concerted Roles of ATR, DNA-PK, and Chk1 in Countering Replication Stress during S Phase.
DNA binding and unwinding activities associated with intracytoplasmic a particles isolated from mouse mammary tumors.
Drug release system controlled by near infrared light.
Evading immune surveillance via tyrosine phosphorylation of nuclear PCNA.
Evaluation of APOBEC3B Recognition Motifs by NMR Reveals Preferred Substrates.
Experimental study of antiangiogenic gene therapy targeting VEGF in oral cancer.
From RNA World to SARS-CoV-2: The Edited Story of RNA Viral Evolution.
From RPA to BRCA2: lessons from single-stranded DNA binding by the OB-fold.
High Ki67, Bax, and thymidylate synthase expression well correlates with response to chemoradiation therapy in locally advanced rectal cancers: proposal of a logistic model for prediction.
Highly parallel single-molecule amplification approach based on agarose droplet polymerase chain reaction for efficient and cost-effective aptamer selection.
Histopathological and immunohistochemical evaluations of breast cancer treated with radiofrequency ablation.
Human papillomavirus mediated inhibition of DNA damage sensing and repair drives skin carcinogenesis.
In vivo fluorescence imaging of hepatocellular carcinoma using a novel GPC3-specific aptamer probe.
Induction of cytotoxicity and ssDNA breaks by 9-bromo-5-morpholino-tetrazolo[1,5-c]quinazoline in tumor cells cultured in vitro.
Long-term outcome of breast cancer patients treated with radiofrequency ablation.
Manifold expression of new cellular genes in human lymphoid neoplasia.
Mechanisms shaping the mutational landscape of the FRA3B/FHIT-deficient cancer genome.
Mouse APOBEC1 cytidine deaminase can induce somatic mutations in chromosomal DNA.
Mucosal high apoptotic activity and low p21WAF1/CIP1 expression and submucosal low proliferative activity in superficially spreading early gastric cancers: comparison with the penetrating growth type.
Novel Ratiometric Fluorescent Nanothermometers Based on Fluorophores-Labeled Short Single-Stranded DNA.
Nucleic Acid-Gated Covalent Organic Frameworks for Cancer-Specific Imaging and Drug Release.
Overexpression of p8 is inversely correlated with apoptosis in pancreatic cancer.
PARPi Triggers the STING-Dependent Immune Response and Enhances the Therapeutic Efficacy of Immune Checkpoint Blockade Independent of BRCAness.
Precise and label-free tumour cell recognition based on a black phosphorus nanoquenching platform.
Prognostic significance of apoptotic cell death in bladder cancer: a tissue microarray study on 179 urothelial carcinomas from cystectomy specimens.
Promotion of BRCA2-Dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry.
Quadruplex DNA: A Promising Drug Target For The Medicinal Inorganic Chemist.
Radiosensitization by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide under oxia and hypoxia in human colon cancer cells.
Recent advances of aptasensors for exosomes detection.
Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation.
Repair-specific functions of replication protein A.
Replication Gaps Underlie BRCA Deficiency and Therapy Response.
REV1-Pol? maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps.
Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity.
Rolling circle amplification and graphene-based sensor-on-a-chip for sensitive detection of serum circulating miRNAs.
RPA shields inherited DNA lesions for post-mitotic DNA synthesis.
Selective delivery of doxorubicin to EGFR+ cancer cells by Cetuximab-DNA conjugates.
Sensitive detection of p53 tumor suppressor gene using an enzyme-based solid-state electrochemiluminescence sensing platform.
Signal Amplified Gold Nanoparticles for Cancer Diagnosis on Paper-Based Analytical Devices.
Studies on the initiation and elongation reactions in the simian virus 40 DNA replication system.
Telomere Trimming and DNA Damage as Signatures of High Risk Neuroblastoma.
The ?-isoform of BCCIP promotes ADP release from the RAD51 presynaptic filament and enhances homologous DNA pairing.
The anti-tumor effects of calorie restriction are correlated with reduced oxidative stress in ENU-induced gliomas.
The application of capillary electrophoresis for assisting whole-cell aptamers selection by characterizing complete ssDNA distribution.
Uniform palladium nanosheets for fluorimetric detection of circulating tumor DNA.
Unraveling a connection between DNA demethylation repair and cancer.
Which Holds the Key to BRCAness: Inability to Repair the Break, Protect the Fork, or Prevent the Gap?
[Binding of SSB-protein from Ehrlich ascites carcinoma cells with DNA and polyribonucleotides]
[The effect of SSB-protein from Ehrlich ascites carcinoma cells on activity of various enzymes of DNA replication and repair]
Nephritis
Anti-DNA antibodies of IgA class in patients with systemic lupus erythematosus.
Significance of enzyme linked immunosorbent assay (ELISA) for antibodies to double stranded and single stranded DNA in patients with lupus nephritis: correlation with severity of renal histology.
Nephrotic Syndrome
[Measurement of antibodies to double-stranded and single-stranded DNA using bacteriophage lambda DNA as the antigen--avidity of antibodies to DNA in patients with lupus nephritis]
Nervous System Diseases
High prevalence of cyclovirus Vietnam (CyCV-VN) in plasma samples from Madagascan healthy blood donors.
Neuroblastoma
Flow cytometry analysis of single-strand DNA damage in neuroblastoma cell lines using the F7-26 monoclonal antibody.
Stimulation of human neuroblastoma DNA polymerase alpha and primase activities by a protein factor isolated from rat liver chromatin.
Telomere Trimming and DNA Damage as Signatures of High Risk Neuroblastoma.
Newcastle Disease
Generation of ssDNA aptamers as diagnostic tool for Newcastle avian virus.
Obesity
Mice deficient in cryptochrome 1 (cry1 (-/-)) exhibit resistance to obesity induced by a high-fat diet.
Obesity, Abdominal
Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance.
Odontogenic Cysts
Evaluation of collagen in connective tissue walls of odontogenic cysts -A histochemical study.
Orthomyxoviridae Infections
Investigating porcine parvoviruses genogroup 2 infection using in situ polymerase chain reaction.
Ovarian Neoplasms
Active DNA end processing in micronuclei of ovarian cancer cells.
Novel ssDNA Ligand Against Ovarian Cancer Biomarker CA125 With Promising Diagnostic Potential.
Pancreatic Neoplasms
Elucidation and Structural Modeling of CD71 as a Molecular Target for Cell-Specific Aptamer Binding.
Papilloma
Electrochemical detection of hepatitis B and papilloma virus DNAs using SWCNT array coated with gold nanoparticles.
Paramyxoviridae Infections
Screening and Identification of ssDNA Aptamers against HN Protein for Detection of Bovine Parainfluenza Virus Type 3 Antibodies in Serum.
Parasitemia
Induction of ssDNA-binding autoantibody secreting B cell immunity during murine malaria infection is a critical part of the protective immune responses.
Photosensitivity Disorders
Further characterization of monoclonal antibody indicates specificity for (6-4)-dipyrimidine photoproducts.
Pilomatrixoma
Comparative Immunohistochemical Analyses on the Modes of Cell Death/Keratinization in Epidermal Cyst, Trichilemmal Cyst, and Pilomatricoma.
Plant Diseases
A geminivirus-related DNA mycovirus that confers hypovirulence to a plant pathogenic fungus.
Pneumonia
Alicaforsen. Isis Pharmaceuticals.
Porcine Reproductive and Respiratory Syndrome
Investigating porcine parvoviruses genogroup 2 infection using in situ polymerase chain reaction.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Manifold expression of new cellular genes in human lymphoid neoplasia.
Prostatic Neoplasms
Doxorubicin Loaded DNA Aptamer Linked Myristilated Chitosan Nanogel for Targeted Drug Delivery to Prostate Cancer.
The value of fluorimetry (Qubit) and spectrophotometry (NanoDrop) in the quantification of cell-free DNA (cfDNA) in malignant melanoma and prostate cancer patients.
Proteinuria
Extracorporeal immunoadsorption: initial experience in human systemic lupus erythematosus.
Rabies
Isolation of ssDNA aptamers that inhibit rabies virus.
Retinoblastoma
Stimulation of DNA polymerase alpha activity by cdk2-phosphorylated Rb protein.
Ultrashort ssDNA in Retinoblastoma Patients Blood Plasma Detected by a Novel High Resolution HPLC Technique: a Preliminary Report.
Rheumatic Diseases
Cross-reactive rheumatoid factors in rheumatoid arthritis with extra-articular disease.
Salmonella Infections
Development of ssDNA aptamers for the sensitive detection of Salmonella typhimurium and Salmonella enteritidis.
Scleroderma, Localized
Antinuclear and anti-single-stranded DNA antibodies in morphea and generalized morphea.
Morphea in Adults and Children Cohort III: Nested Case-Control Study-The Clinical Significance of Autoantibodies in Morphea.
Scrapie
Evidence that homologous ssDNA is present in scrapie, Creutzfeldt-Jakob disease, and bovine spongiform encephalopathy.
Evidence that single-stranded DNA wrapped around the tubulofilamentous particles termed "nemaviruses" is the genome of the scrapie agent.
Molecular cloning of single-stranded DNA purified from scrapie-infected hamster brain.
Severe Acute Respiratory Syndrome
An efficient method for recovery of target ssDNA based on amino-modified silica-coated magnetic nanoparticles.
MCE-electrochemical detection for following interactions of ssDNA and dsDNA with methylene blue.
Shock, Septic
Mice with the xid B cell defect are less susceptible to developing Staphylococcus aureus-induced arthritis.
Skin Diseases
Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA.
Skin Neoplasms
Development of liquid chromatography tandem mass spectrometry method to quantify cyclobutane pyrimidine dimer photolyase activity by detection of 15mer oligonucleotide as reaction product.
Efficacy of a photolyase-based device in the treatment of cancerization field in patients with actinic keratosis and non-melanoma skin cancer.
Powerful skin cancer protection by a CPD-photolyase transgene.
Sleep Deprivation
Overexpression of circadian clock protein cryptochrome (CRY) 1 alleviates sleep deprivation-induced vascular inflammation in a mouse model.
Sleep Initiation and Maintenance Disorders
Human CRY1 variants associate with attention deficit/hyperactivity disorder.
Spinal Cord Injuries
Oligonucleotide-functionalized hydrogels for sustained release of small molecule (aptamer) therapeutics.
Starvation
Nutritional control of elongation of DNA replication by (p)ppGpp.
Stomach Neoplasms
An ssDNA aptamer selected by Cell-SELEX for the targeted imaging of poorly differentiated gastric cancer tissue.
Cryptochrome 1 Alleviates the Antiproliferative Effect of Isoproterenol on Human Gastric Cancer Cells.
The Ratio of ssDNA to dsDNA in Circulating Cell-Free DNA Extract is a Stable Indicator for Diagnosis of Gastric Cancer.
[Clinicopathological and biological features of micrometastasis in early gastric cancers]
Subacute Sclerosing Panencephalitis
SspABCD-SspFGH Constitutes a New Type of DNA Phosphorothioate-Based Bacterial Defense System.
Superinfection
RexAB proteins of bacteriophage lambda enhance the effect of photolyase-dimer complexes on lacZ gene expression in Escherichia coli.
Single-stranded DNA 'blue' T7 promoter plasmids: a versatile tandem promoter system for cloning and protein engineering.
The ori of filamentous phage phi Lf is located within the gene encoding the replication initiation protein.
Telangiectasis
A UVR-Induced G2-Phase Checkpoint Response to ssDNA Gaps Produced by Replication Fork Bypass of Unrepaired Lesions Is Defective in Melanoma.
Biochemical properties of mammalian TREX1 and its association with DNA replication and inherited inflammatory disease.
Tetanus
Clonidine inhibits anti-non-Gal IgM xenoantibody elicited in multiple pig-to-primate models.
High-affinity antibodies to ssDNA are produced by CD-B cells in systemic lupus erythematosus patients.
Human monoclonal rheumatoid factor-like antibodies from CD5 (Leu-1)+ B cells are polyreactive.
Polyreactivity and antigen specificity of human xenoreactive monoclonal and serum natural antibodies.
Probing the normal and autoimmune B cell repertoire with Epstein-Barr virus. Frequency of B cells producing monoreactive high affinity autoantibodies in patients with Hashimoto's disease and systemic lupus erythematosus.
Production of heterohybridomas secreting autoreactive and polyreactive human monoclonal antibodies.
Quantitative immunoassays for type II collagen and its cyanogen bromide peptides.
Rheumatoid factor specificity of a VH3-encoded antibody is dependent on the heavy chain CDR3 region and is independent of protein A binding.
Transfusion Reaction
Single-stranded DNA aptamer targeting and neutralization of anti-D alloantibody: a potential therapeutic strategy for haemolytic diseases caused by Rhesus alloantibody.
Tuberculosis
A homogeneous signal-on strategy for the detection of rpoB genes of Mycobacterium tuberculosis based on electrochemiluminescent graphene oxide and ferrocene quenching.
A Single ssDNA Aptamer Binding to Mannose-Capped Lipoarabinomannan of Bacillus Calmette-Guérin Enhances Immunoprotective Effect against Tuberculosis.
Development of ssDNA aptamers as potent inhibitors of Mycobacterium tuberculosis acetohydroxyacid synthase.
Evaluation of DNA primase DnaG as a potential target for antibiotics.
Function of ssDNA aptamer and aptamer pool against Mycobacterium tuberculosis in a mouse model.
Generation and application of ssDNA aptamers against glycolipid antigen ManLAM of Mycobacterium tuberculosis for TB diagnosis.
Identification and application of ssDNA aptamers against H??Rv in the detection of Mycobacterium tuberculosis.
Investigating mycobacterial topoisomerase I mechanism from the analysis of metal and DNA substrate interactions at the active site.
Mycobacterial Ku and ligase proteins constitute a two-component NHEJ repair machine.
Mycobacterium tuberculosis DinG is a structure-specific helicase that unwinds G4 DNA: implications for targeting G4 DNA as a novel therapeutic approach.
Rolling circle amplification and graphene-based sensor-on-a-chip for sensitive detection of serum circulating miRNAs.
Selection of a new Mycobacterium tuberculosis H37Rv aptamer and its application in the construction of a SWCNT/aptamer/Au-IDE MSPQC H37Rv sensor.
Selection of Nucleic Acid Aptamers Specific for Mycobacterium tuberculosis.
Structural insights into the interaction of helicase and primase in Mycobacterium tuberculosis.
The selection and application of ssDNA aptamers against MPT64 protein in Mycobacterium tuberculosis.
Vaccinia
Comparison of the genome sequence of FP9, an attenuated, tissue culture-adapted European strain of Fowlpox virus, with those of virulent American and European viruses.
Stimulation of vaccinia virion DNA helicase I8R, but not A18R, by a vaccinia core protein L4R, an ssDNA binding protein.
Vaccinia virus G8R protein: a structural ortholog of proliferating cell nuclear antigen (PCNA).
Varicocele
Alkaline and neutral Comet assay profiles of sperm DNA damage in clinical groups.
Vesicular Stomatitis
The first strand transfer reaction of HIV-1 reverse transcription is more efficient in infected cells than in cell-free natural endogenous reverse transcription reactions.
Virus Diseases
Functional analysis of a novel ?V1 gene identified in a geminivirus betasatellite.
Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies.
Porcine circovirus type 2 stimulates plasmacytoid dendritic cells in the presence of IFN-gamma.
Single cell ecogenomics reveals mating types of individual cells and ssDNA viral infections in the smallest photosynthetic eukaryotes.
Tomato yellow leaf curl virus intergenic siRNAs target a host long noncoding RNA to modulate disease symptoms.
Werner Syndrome
Checkpoint Defects Elicit a WRNIP1-Mediated Response to Counteract R-Loop-Associated Genomic Instability.
Mechanistic analysis of Xenopus EXO1's function in 5'-strand resection at DNA double-strand breaks.
Wiskott-Aldrich Syndrome
Molecular and cellular impact of Psoriasin (S100A7) on the healing of human wounds.
Xeroderma Pigmentosum
An in vivo analysis of MMC-induced DNA damage and its repair.
Evidence that xeroderma pigmentosum cells from complementation group E are deficient in a homolog of yeast photolyase.
Expression of a mammalian DNA photolyase confers light-dependent repair activity and reduces mutations of UV-irradiated shuttle vectors in xeroderma pigmentosum cells.
Replication independent ATR signalling leads to G2/M arrest requiring Nbs1, 53BP1 and MDC1.