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Information on EC 4.1.3.24 - malyl-CoA lyase

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EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.3 Oxo-acid-lyases
                4.1.3.24 malyl-CoA lyase
IUBMB Comments
The enzymes from Rhodobacter species catalyse a step in the ethylmalonyl-CoA pathway for acetate assimilation [3,5]. The enzyme from halophilic bacteria participate in the methylaspartate cycle and catalyse the reaction in the direction of malyl-CoA formation . The enzyme from the bacterium Chloroflexus aurantiacus, which participates in the 3-hydroxypropanoate cycle for carbon assimilation, also has the activity of EC 4.1.3.25, (3S)-citramalyl-CoA lyase [2,4].
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The enzyme appears in viruses and cellular organisms
Synonyms
(3S)-malyl-CoA lyase, (3S)-malyl-coenzyme A lyase, L-malyl-CoA lyase/beta-methylmalyl-CoA lyase, L-malyl-CoA/beta-methylmalyl-CoA lyase, L-malyl-coenzyme A/beta-methylmalyl-coenzyme A lyase, lyase, malyl coenzyme A, malyl coenzyme A lyase, malyl-CoA lyase, malyl-CoA/beta-methylmalyl-CoA lyase, malyl-CoA/beta-methylmalyl-CoA/citramalyl-CoA lyase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2R,3S)-2-methylmalyl-CoA = propanoyl-CoA + glyoxylate
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(2)
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(S)-malyl-CoA = acetyl-CoA + glyoxylate
show the reaction diagram
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