Information on EC 4.1.3.24 - malyl-CoA lyase

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EC Tree
     4 Lyases
         4.1 Carbon-carbon lyases
             4.1.3 Oxo-acid-lyases
                4.1.3.24 malyl-CoA lyase
IUBMB Comments
The enzymes from Rhodobacter species catalyse a step in the ethylmalonyl-CoA pathway for acetate assimilation [3,5]. The enzyme from halophilic bacteria participate in the methylaspartate cycle and catalyse the reaction in the direction of malyl-CoA formation . The enzyme from the bacterium Chloroflexus aurantiacus, which participates in the 3-hydroxypropanoate cycle for carbon assimilation, also has the activity of EC 4.1.3.25, (3S)-citramalyl-CoA lyase [2,4].
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
malyl-coa lyase, l-malyl-coa lyase/beta-methylmalyl-coa lyase, malyl coenzyme a lyase, malyl-coa/beta-methylmalyl-coa lyase, (3s)-malyl-coa lyase, l-malyl-coa/beta-methylmalyl-coa lyase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(S)-malyl-CoA = acetyl-CoA + glyoxylate
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(2R,3S)-2-methylmalyl-CoA = propanoyl-CoA + glyoxylate
show the reaction diagram
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