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Reference on EC 4.1.2.13 - fructose-bisphosphate aldolase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Misset, O.; Opperdoes, F.R.
Simultaneous purification of hexokinase, class-I fructose-bisphosphate aldolase, triosephosphate isomerase and phosphoglycerate kinase from Trypanosoma brucei
Eur. J. Biochem.
144
475-483
1984
Trypanosoma brucei
Manually annotated by BRENDA team
Morse, D.E.; Horecker, B.L.
The mechanism of action of aldolases
Adv. Enzymol. Relat. Areas Mol. Biol.
31
125-181
1968
Anacystis sp., Aspergillus sp., Bacillus sp. (in: Bacteria), Brucella sp., Candida sp. (in: Saccharomycetales), Chlamydomonas sp., Clostridium sp., Corynebacterium sp., Oryctolagus cuniculus, Escherichia coli, Erwinia sp., Euglena sp., Penicillium sp., Lactobacillus sp., Mycobacterium sp., Pseudomonas sp., Saccharomyces sp., Veillonella sp.
Manually annotated by BRENDA team
Vimard, C.; Orsini, G.; Goldberg, M.E.
Renaturation of acid-denatured rabbit muscle aldolase
Eur. J. Biochem.
51
521-527
1975
Oryctolagus cuniculus
Manually annotated by BRENDA team
Guha, A.
Fructose-diphosphate aldolase from lobster muscle
Methods Enzymol.
42C
223-228
1975
Lobster
Manually annotated by BRENDA team
Willard, J.M.; Gibbs, M.
Fructose-diphosphate aldolase from blue-green algae
Methods Enzymol.
42C
228-234
1975
Synechococcus elongatus PCC 7942 = FACHB-805
-
Manually annotated by BRENDA team
Horecker, B.L.
Fructose bisphosphate aldolase from spinach
Methods Enzymol.
42C
234-239
1975
Spinacia oleracea
-
Manually annotated by BRENDA team
Penhoet, E.E.; Rutter, W.J.
Detection and isolation of mammalian fructose-diphosphate aldolases
Methods Enzymol.
42C
240-249
1975
Oryctolagus cuniculus
Manually annotated by BRENDA team
Lebherz, H.G.; Rutter, W.J.
The class I (Schiff base) fructose-diphosphate aldolase of Peptococcus aerogenes
Methods Enzymol.
42C
249-258
1975
Peptoniphilus asaccharolyticus, Peptoniphilus asaccharolyticus 228
Manually annotated by BRENDA team
Anderson, L.E.; Heinrikson, R.L.; Noyes, C.
Chloroplast and cytoplasmic enzymes
Arch. Biochem. Biophys.
169
262-268
1975
Pisum sativum
Manually annotated by BRENDA team
El-Dorry, H.A.; Bacila, M.
Purification and properties of rabbit heart muscle aldolase
Biochim. Biophys. Acta
480
305-314
1977
Oryctolagus cuniculus
Manually annotated by BRENDA team
Pasha, S.T.; Salahuddin, A.
Isolation of buffalo muscle aldolase and comparison of its properties with those of rabbit muscle aldolase
Biochim. Biophys. Acta
483
435-442
1977
Bos taurus, Oryctolagus cuniculus
Manually annotated by BRENDA team
Yeltman, D.R.; Harris, B.G.
Purification and characterization of aldolase from human erythrocytes
Biochim. Biophys. Acta
484
188-198
1977
Homo sapiens
Manually annotated by BRENDA team
Baldwin, S.A.; Perham, R.N.; Stribling, D.
Purification and characterization of the class-II D-fructose 1,6-bisphosphate aldolase from Escherichia coli (Crookes' strain)
Biochem. J.
169
633-641
1978
Escherichia coli, Escherichia coli Crookes
Manually annotated by BRENDA team
Baldwin, S.A.; Perham, R.N.
Novel kinetic and structural properties of the class-I D-fructose 1,6-bisphosphate aldolase from Escherichia coli (Crookes' strain)
Biochem. J.
169
643-652
1978
Escherichia coli, Escherichia coli Crookes
Manually annotated by BRENDA team
Fernandez-Sousa, J.M.; Gavilanes, F.G.; Gavilanes, J.G.; Paredes, J.A.
D-Fructose 1,6-bisphosphate aldolase from the dipteran Ceratitis capitata
Arch. Biochem. Biophys.
188
456-465
1978
Ceratitis capitata
Manually annotated by BRENDA team
Bang, S.S.; Baumann, P.
Properties of fructose-1,6-diphosphate phosphatase and fructose-1,6-diphosphate aldolase from Pseudomonas putida
Curr. Microbiol.
1
5-9
1978
Pseudomonas putida
-
Manually annotated by BRENDA team
Chappel, A.; Hoogenraad, N.J.; Holmes, R.S.
Purification and properties of native form of rabbit liver aldolase
Biochem. J.
175
377-382
1978
Oryctolagus cuniculus
Manually annotated by BRENDA team
Jones, L.P.; Morita, R.Y.; Becker, R.R.
Fructoser-1,6-bisphosphate aldolase from Vibrio marinus. A psychrophilic marine bacterium
Z. Allg. Mikrobiol.
19
97-106
1979
Moritella marina
Manually annotated by BRENDA team
Brenner-Holzach, O.
Properties of fructose 1,6-diphosphate aldolase from Drosophila melanogaster
Arch. Biochem. Biophys.
194
321-327
1979
Drosophila melanogaster
Manually annotated by BRENDA team
Gtz, F.; Fischer, S.; Schleifer, K.H.
Purification and characterisation of an unusually heat-stable and acid/base-stable class I fructose-1,6-bisphosphate aldolase from Staphylococcus aureus
Eur. J. Biochem.
108
295-301
1980
Staphylococcus aureus
Manually annotated by BRENDA team
Schettino, C.M.; Lima, D.F.; Leyton, J.F.; ElDorry, H.A.; Bacila, M.
Studies on the structure of aldolase A from chicken muscle
Biochim. Biophys. Acta
667
411-420
1981
Gallus gallus
Manually annotated by BRENDA team
Murphy, D.J.; Walker, D.A.
Aldolase from wheat leaves - its properties and subcellular distribution
FEBS Lett.
134
163-166
1981
Triticum aestivum
-
Manually annotated by BRENDA team
Ujita, S.; Kimura, K.
Fructose-1,6-bisphosphate aldolase from Bacillus subtilis
Methods Enzymol.
90
235-241
1982
Bacillus subtilis
Manually annotated by BRENDA team
Jayanthi Bai, N.; Ramachandra Pai, M.; Suryanarayana Murthy, P.; Venkitasubramanian, T.A.
Fructose-bisphosphate aldolases from Mycobacteria
Methods Enzymol.
90
241-250
1982
Mycobacterium tuberculosis, Mycolicibacterium smegmatis
Manually annotated by BRENDA team
Yeltman, D.R.; Harris, B.G.
Fructose-bisphosphate aldolase from human erythrocytes
Methods Enzymol.
90
251-254
1982
Homo sapiens
Manually annotated by BRENDA team
Kochman, M.; Kwiatowska, D.
Fructose-bisphosphate aldolase from Ascaris suum
Methods Enzymol.
90
254-258
1982
Ascaris suum
Manually annotated by BRENDA team
Kochman, M.; Hargrave, P.A.; Buczylko, J.
Fructose-bisphosphate aldolase from Helix pomatia
Methods Enzymol.
90
259-263
1982
Helix pomatia
Manually annotated by BRENDA team
Gasperini, C.; Pupillo, P.
Aldolase isoenzymes of maize leaves
Plant Sci. Lett.
28
163-171
1983
Zea mays
-
Manually annotated by BRENDA team
Krueger, I.; Schnarrenberger, C.
Purification, subunit structure and immunological comparison of fructose-bisphosphate aldolases from spinach and corn leaves
Eur. J. Biochem.
136
101-106
1983
Spinacia oleracea, Zea mays
Manually annotated by BRENDA team
Lebherz, H.G.; Leadbetter, M.M.; Bradshaw, R.A.
Isolation and characterization of the cytosolic and chloroplast forms of spinach leaf fructose diphosphate aldolase
J. Biol. Chem.
259
1011-1017
1984
Spinacia oleracea
Manually annotated by BRENDA team
Abraham, M.; Horvath, L.; Simon, M.; Szajani, B.; Boross, L.
Characterization and comparison of soluble and immobilized pig muscle aldolases
Appl. Biochem. Biotechnol.
11
91-100
1985
Sus scrofa
Manually annotated by BRENDA team
Bais, R.; James, H.M.; Rofe, A.M.; Conyers, A.J.
The purification and properties of human liver ketohexokinase. A role for ketohexokinase and fructose-bisphosphate aldolase in the metabolic production of oxalate from xylitol
Biochem. J.
230
53-60
1985
Homo sapiens
Manually annotated by BRENDA team
Schnarrenberger, C.; Kruger, I.
Distinction between cytosol and chloroplast fructose-bisphosphate aldolases from pea, wheat, and corn leaves
Plant Physiol.
80
301-304
1986
Pisum sativum, Spinacia oleracea, Triticum aestivum, Zea mays
Manually annotated by BRENDA team
Jacobshagen, S.; Schnarrenberger, C.
Two class I aldolases in the green alga Chara foetida (Charophyceae)
Plant Physiol.
87
78-82
1988
Chara vulgaris
Manually annotated by BRENDA team
Pagliaro, L.; Taylor, D.L.
Aldolase exists in both the fluid and solid phases of cytoplasm
J. Cell Biol.
107
981-991
1988
Oryctolagus cuniculus
Manually annotated by BRENDA team
Gross, W.; Lenze, D.; Nowitzki, U.; Weiske, J.; Schnarrenberger, C.
Characterization, cloning, and evolutionary history of the chloroplast and cytosolic class I aldolases of the red alga Galdieria sulphuraria
Gene
230
7-14
1999
Galdieria sulphuraria
Manually annotated by BRENDA team
Blonski, C.; de Moissac, D.; Perie, J.; Sygusch, J.
Inhibition of rabbit muscle aldolase by phosphorylated aromatic compounds
Biochem. J.
323
71-77
1997
Oryctolagus cuniculus
Manually annotated by BRENDA team
Holden, C.P.; Storey, K.B.
Purification and characterization of aldolase from the cold hardy insect Epiblema scudderiana: enzyme role in glycerol biosynthesis
Insect Biochem. Mol. Biol.
24
265-270
1994
Epiblema scudderiana
-
Manually annotated by BRENDA team
Botha, F.C.; O'Kennedy, M.M.
Characterization of the cytosolic aldolase from germinating Phaseolus vulgaris seed
J. Plant Physiol.
135
433-438
1989
Phaseolus vulgaris
-
Manually annotated by BRENDA team
Gefflaut, T.; Blonski, C.; Perie, J.; Willson, M.
Class I aldolases: substrate specificity, mechanism, inhibitors and structural aspects
Prog. Biophys. Mol. Biol.
63
301-340
1995
Bacteria, Mammalia
Manually annotated by BRENDA team
Berthiaume, L.; Beaudry, D.; Lazure, C.; Tolan, D.R.; Sygusch, J.
Recombinant anaerobic maize aldolase: overexpression, characterization, and metabolic implications
Arch. Biochem. Biophys.
272
281-289
1989
Zea mays
Manually annotated by BRENDA team
Szwergold, B.S.; Ugurbil, K.; Brown, T.R.
Properties of fructose-1,6-bisphosphate aldolase from Escherichia coli: an NMR analysis
Arch. Biochem. Biophys.
317
244-252
1995
Escherichia coli
Manually annotated by BRENDA team
Kai, T.; Sugimoto, Y.; Kusakabe, T.; Zhang, R.; Koga, K.; Hori, K.
Gene structure and multiple mRNA species of Drosophila melanogaster aldolase generating three isoenzymes with different enzymatic properties
J. Biochem.
112
677-688
1992
Drosophila melanogaster
Manually annotated by BRENDA team
Kusakabe, T.; Motoki, K.; Hori, K.
Human aldolase C: characterization of the recombinant enzyme expressed in Escherichia coli
J. Biochem.
115
1172-1177
1994
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Zhang, R.; Kusakabe, T.; Iwanaga, N.; Sugimoto, Y.; Kondo, K.; Takasaki, Y.; Imai, T.; Yoshida, M.; Hori, K.
Lamprey fructose-1,6-bisphosphate aldolase: characterization of the muscle-type and non-muscle-type isozymes
Arch. Biochem. Biophys.
341
170-176
1997
Lethenteron camtschaticum
Manually annotated by BRENDA team
Hodgson, R.J.; Plaxton, W.C.
Purification and characterization of cytosolic fructose-1,6-bisphosphate aldolase from endosperm of germinated castor oil seeds
Arch. Biochem. Biophys.
355
189-196
1998
Ricinus communis
Manually annotated by BRENDA team
Nicholas, P.C.
Fructose-1,6-bisphosphate aldolases from guinea-pig cerebral cortex: is the kinetic behaviour a technical artefact
Biochem. Soc. Trans.
17
574-575
1989
Cavia porcellus
-
Manually annotated by BRENDA team
Doyle, S.A.; Tolan, D.R.
Characterization of recombinant human aldolase B and purification by metal chelate chromatography
Biochem. Biophys. Res. Commun.
206
902-908
1995
Homo sapiens
Manually annotated by BRENDA team
Ferroni, E.L.
Slow reversible inhibition of rabbit muscle aldolase by D-erythrulose 1-phosphate
Biochem. Biophys. Res. Commun.
176
511-516
1991
Oryctolagus cuniculus
Manually annotated by BRENDA team
Nakagawa, T.; Nagayama, F.
Enzymatic properties of fish muscle aldolase
Comp. Biochem. Physiol. B
92
405-410
1989
Cyprinus carpio, Pagrus major, Scomber japonicus
Manually annotated by BRENDA team
Hall, D.R.; Leonard, G.A.; Reed, C.D.; Watt, C.I.; Berry, A.; Hunter, W.N.
The crystal structure of Escherichia coli class II fructose-1,6-bisphosphate aldolase in complex with phosphoglycolohydroxamate reveals details of mechanism and specificity
J. Mol. Biol.
287
383-394
1999
Escherichia coli (P0AB71), Escherichia coli
Manually annotated by BRENDA team
Pelzer-Reith, B.; Wiegand, S.; Scharrenberger, C.
Plastid class I and cytosol class II aldolase of Euglena gracilis
Plant Physiol.
106
1137-1144
1994
Euglena gracilis
Manually annotated by BRENDA team
El-Dabaa, E.; El-Sayed, A.; Karim, A.M.; Eldesoky, H.M.; Fahim, F.A.; LoVerde, P.T.; Saber, M.A.
Cloning and characterization of Schistosoma mansoni fructose-1,6-bisphosphate aldolase isoenzyme
J. Parasitol.
84
954-960
1998
Schistosoma mansoni
Manually annotated by BRENDA team
Callens, M.; Kuntz, D.A.; Opperdoes, F.R.
Kinetic properties of fructose bisphosphate aldolase from rabbit muscle and Staphylococcus aureus
Mol. Biochem. Parasitol.
47
1-10
1991
Oryctolagus cuniculus, Staphylococcus aureus, Trypanosoma brucei
Manually annotated by BRENDA team
Dbeli, H.; Trzeciak, A.; Gillessen, A.; Matile, H.; Srivastava, I.K.; Perrin, L.H.; Jakob, P.E.; Certa, U.
Expression, purification, biochemical characterization and inhibition of recombinant Plasmodium falciparum aldolase
Mol. Biochem. Parasitol.
41
259-268
1990
Plasmodium falciparum
Manually annotated by BRENDA team
Kusakabe, T.; Motoki, K.; Sugimoto, Y.; Takasaki, Y.; Hori, K.
Human aldolase B: liver-specific properties of the isoenzyme depend on type B isozyme group-specific sequences
Protein Eng.
7
1387-1393
1994
Homo sapiens
Manually annotated by BRENDA team
Chevalier, N.; Callens, M.; Michels, P.A.M.
High-level expression of Trypanosoma brucei fructose 1,6-bisphosphate aldolase in Escherichia coli and purification of the enzyme
Protein Expr. Purif.
6
39-44
1995
Trypanosoma brucei
Manually annotated by BRENDA team
Keaton, A.; Gunasekaran, M.
Purification and properties of fructose 1,6-biphosphate aldolase from Nocardia asteroides
Biomed. Lett.
48
247-254
1993
Nocardia asteroides
-
Manually annotated by BRENDA team
Brockamp, H.P.; Kula, M.R.
Purification and characterization of a class I fructose 1,6-bisphosphate aldolase from Staphylococcus carnosus
Appl. Microbiol.
34
287-291
1990
Staphylococcus carnosus
-
Manually annotated by BRENDA team
Moorhead, G.B.G.; Plaxton, W.C.
Purification and characterization of cytosolic aldolase from carrot storage root
Biochem. J.
269
133-139
1990
Daucus carota
Manually annotated by BRENDA team
De Montigny, C.; Sygusch, J.
Functional characterization of an extreme thermophilic class II fructose-1,6-bisphosphate aldolase
Eur. J. Biochem.
241
243-248
1996
Thermus aquaticus
Manually annotated by BRENDA team
Kwiatkowska, D.; Modrzycka, T.; Sidorowicz, A.
Inhibition of fructose diphosphate aldolase by phosphatidylserine liposomes
Gen. Physiol. Biophys.
13
425-431
1994
Oryctolagus cuniculus
Manually annotated by BRENDA team
Dalby, A.; Dauter, Z.; Littlechild, J.A.
Crystal structure of human muscle aldolase complexed with fructose 1,6-bisphosphate: mechanistic implications
Protein Sci.
8
291-297
1999
Homo sapiens
Manually annotated by BRENDA team
Dalby, A.R.; Tolan, D.R.; Littlechild, J.A.
The structure of human liver fructose-1,6-bisphosphate aldolase
Acta Crystallogr. Sect. D
57
1526-1533
2001
Homo sapiens
Manually annotated by BRENDA team
Sauve, V.; Sygusch, J.
Crystallization and preliminary X-ray analysis of native and selenomethionine fructose-1,6-bisphosphate aldolase from Thermus aquaticus
Acta Crystallogr. Sect. D
57
310-313
2001
Thermus aquaticus
Manually annotated by BRENDA team
Hall, D.R.; Kemp, L.E.; Leonard, G.A.; Marshall, K.; Berry, A.; Hunter, W.N.
The organization of divalent cations in the active site of cadmium Escherichia coli fructose-1,6-bisphosphate aldolase
Acta Crystallogr. Sect. D
59
611-614
2003
Escherichia coli
Manually annotated by BRENDA team
MacDonald, J.A.; Storey, K.B.
Purification and characterization of fructose bisphosphate aldolase from the ground squirrel, Spermophilus lateralis: enzyme role in mammalian hibernation
Arch. Biochem. Biophys.
408
279-285
2002
Oryctolagus cuniculus, Callospermophilus lateralis
Manually annotated by BRENDA team
Malay, A.D.; Procious, S.L.; Tolan, D.R.
The temperature dependence of activity and structure for the most prevalent mutant aldolase B associated with hereditary fructose intolerance
Arch. Biochem. Biophys.
408
295-304
2002
Homo sapiens
Manually annotated by BRENDA team
Choi, K.H.; Mazurkie, A.S.; Morris, A.J.; Utheza, D.; Tolan, D.R.; Allen, K.N.
Structure of a fructose-1,6-bis(phosphate) aldolase liganded to its natural substrate in a cleavage-defective mutant at 2.3 Ang
Biochemistry
38
12655-12664
1999
Oryctolagus cuniculus (P00883), Oryctolagus cuniculus
Manually annotated by BRENDA team
Choi, K.H.; Shi, J.; Hopkins, C.E.; Tolan, D.R.; Allen, K.N.
Snapshots of catalysis: the structure of fructose-1,6-(bis)phosphate aldolase covalently bound to the substrate dihydroxyacetone phosphate
Biochemistry
40
13868-13875
2001
Homo sapiens
Manually annotated by BRENDA team
Zannetti, M.T.; Walter, C.; Knorst, M.; Fessner, W.D.
Enzymes in organic synthesis. Part 14. Fructose 1,6-bisphosphate aldolase from Staphylococcus carnosus: overexpression, structure prediction, stereoselectivity, and application in the synthesis of bicyclic sugars
Chem. Eur. J.
5
1882-1890
1999
Staphylococcus carnosus
-
Manually annotated by BRENDA team
Zgiby, S.M.; Thomson, G.J.; Qamar, S.; Berry, A.
Exploring substrate binding and discrimination in fructose1, 6-bisphosphate and tagatose 1,6-bisphosphate aldolases
Eur. J. Biochem.
267
1858-1868
2000
Escherichia coli
Manually annotated by BRENDA team
Esposito, G.; Vitagliano, L.; Santamaria, R.; Viola, A.; Zagari, A.; Salvatore, F.
Structural and functional analysis of aldolase B mutants related to hereditary fructose intolerance
FEBS Lett.
531
152-156
2002
Homo sapiens (P05062), Homo sapiens
Manually annotated by BRENDA team
McCarthy, J.S.; Wieseman, M.; Tropea, J.; Kaslow, D.; Abraham, D.; Lustigman, S.; Tuan, R.; Guderian, R.H.; Nutman, T.B.
Onchocerca volvulus glycolytic enzyme fructose-1,6-bisphosphate aldolase as a target for a protective immune response in humans
Infect. Immun.
70
851-858
2002
Onchocerca volvulus (Q9U9R9), Onchocerca volvulus
Manually annotated by BRENDA team
Choi, K.H.; Tolan, D.R.
Presteady-state kinetic evidence for a ring-opening activity in fructose-1,6-(bis)phosphate aldolase
J. Am. Chem. Soc.
126
3402-3403
2004
Homo sapiens
Manually annotated by BRENDA team
Ta, T.V.; Takano, R.; Kamei, K.; Xu, X.Y.; Kariya, Y.; Yoshida, K.; Hara, S.
Fructose 1,6-bisphosphate aldolase is a heparin-binding protein
J. Biochem.
125
554-559
1999
Bos taurus
Manually annotated by BRENDA team
Rellos, P.; Sygusch, J.; Cox, T.M.
Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis
J. Biol. Chem.
275
1145-1151
2000
Homo sapiens
Manually annotated by BRENDA team
Siebers, B.; Brinkmann, H.; Dorr, C.; Tjaden, B.; Lilie, H.; van der Oost, J.; Verhees, C.H.
Archaeal fructose-1,6-bisphosphate aldolases constitute a new family of archaeal type class I aldolase
J. Biol. Chem.
276
28710-28718
2001
Pyrococcus furiosus (P58314), Pyrococcus furiosus, Thermoproteus tenax (P58315), Thermoproteus tenax
Manually annotated by BRENDA team
Maurady, A.; Zdanov, A.; De Moissac, D.; Beaudry, D.; Sygusch, J.
A conserved glutamate residue exhibits multifunctional catalytic roles in D-fructose-1,6-bisphosphate aldolases
J. Biol. Chem.
277
9474-9483
2002
Oryctolagus cuniculus (P00883)
Manually annotated by BRENDA team
Pezza, J.A.; Choi, K.H.; Berardini, T.Z.; Beernink, P.T.; Allen, K.N.; Tolan, D.R.
Spatial clustering of isozyme-specific residues reveals unlikely determinants of isozyme specificity in fructose-1,6-bisphosphate aldolase
J. Biol. Chem.
278
17307-17313
2003
Oryctolagus cuniculus (P00883)
Manually annotated by BRENDA team
Plater, A.R.; Zgiby, S.M.; Thomson, G.J.; Qamar, S.; Wharton, C.W.; Berry, A.
Conserved residues in the mechanism of the E. coli Class II FBP-aldolase
J. Mol. Biol.
285
843-855
1999
Escherichia coli (P0AB71), Escherichia coli
Manually annotated by BRENDA team
Zgiby, S.; Plater, A.R.; Bates, M.A.; Thomson, G.J.; Berry, A.
A functional role for a flexible loop containing Glu182 in the class II fructose-1,6-bisphosphate aldolase from Escherichia coli
J. Mol. Biol.
315
131-140
2002
Escherichia coli
Manually annotated by BRENDA team
de Walque, S.; Opperdoes, F.R.; Michels, P.A.M.
Cloning and characterization of Leishmania mexicana fructose-1,6-bisphosphate aldolase
Mol. Biochem. Parasitol.
103
279-283
1999
Leishmania mexicana (Q9U5N6), Leishmania mexicana
Manually annotated by BRENDA team
Nakahara, K.; Yamamoto, H.; Miyake, C.; Yokota, A.
Purification and characterization of class-I and class-II fructose-1,6-bisphosphate aldolases from the cyanobacterium Synechocystis sp. PCC 6803
Plant Cell Physiol.
44
326-333
2003
Synechocystis sp.
Manually annotated by BRENDA team
Michelis, R.; Gepstein, S.
Identification and characterization of a heat-induced isoform of aldolase in oat chloroplast
Plant Mol. Biol.
44
487-498
2000
Avena sativa
Manually annotated by BRENDA team
Sauve, V.; Sygusch, J.
Molecular cloning, expression, purification, and characterization of fructose-1,6-bisphosphate aldolase from Thermus aquaticus
Protein Expr. Purif.
21
293-302
2001
Thermus aquaticus (Q9RHA2), Thermus aquaticus
Manually annotated by BRENDA team
Schoevaart, R.; Van Rantwijk, F.; Sheldon, R.A.
Class I fructose-1,6-bisphosphate aldolases as catalysts for asymmetric aldol reactions
Tetrahedron
10
705-711
1999
Staphylococcus carnosus
-
Manually annotated by BRENDA team
Esposito, G.; Vitagliano, L.; Costanzo, P.; Borrelli, L.; Barone, R.; Pavone, L.; Izzo, P.; Zagari, A.; Salvatore, F.
Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function
Biochem. J.
380
51-56
2004
Homo sapiens (P04075), Homo sapiens
Manually annotated by BRENDA team
Lorentzen, E.; Siebers, B.; Hensel, R.; Pohl, E.
Structure, function and evolution of the Archaeal class I fructose-1,6-bisphosphate aldolase
Biochem. Soc. Trans.
32
259-263
2004
Thermoproteus tenax
Manually annotated by BRENDA team
Lorentzen, E.; Siebers, B.; Hensel, R.; Pohl, E.
Mechanism of the Schiff base forming fructose-1,6-bisphosphate aldolase: structural analysis of reaction intermediates
Biochemistry
44
4222-4229
2005
Thermoproteus tenax (P58315), Thermoproteus tenax
Manually annotated by BRENDA team
Dax, C.; Coincon, M.; Sygusch, J.; Blonski, C.
Hydroxynaphthaldehyde phosphate derivatives as potent covalent Schiff base inhibitors of fructose-1,6-bisphosphate aldolase
Biochemistry
44
5430-5443
2005
Oryctolagus cuniculus (P00883), Oryctolagus cuniculus
Manually annotated by BRENDA team
Gavalda, S.; Braga, R.; Dax, C.; Vigroux, A.; Blonski, C.
N-Sulfonyl hydroxamate derivatives as inhibitors of class II fructose-1,6-diphosphate aldolase
Bioorg. Med. Chem.
15
5375-5377
2005
Oryctolagus cuniculus, Escherichia coli
Manually annotated by BRENDA team
Fonvielle, M.; Weber, P.; Dabkowska, K.; Therisod, M.
New highly selective inhibitors of class II fructose-1,6-bisphosphate aldolases
Bioorg. Med. Chem. Lett.
14
2923-2926
2004
Bacillus subtilis, Saccharomyces cerevisiae, Oryctolagus cuniculus
Manually annotated by BRENDA team
Dziewulska-Szwajkowska, D.; Zmojdzian, M.; Dobryszycki, P.; Kochman, M.; Dzugaj, A.
The interaction of FBPase with aldolase: a kinetic and fluorescence investigation on chicken muscle enzymes
Comp. Biochem. Physiol. B
137
115-129
2004
Gallus gallus
Manually annotated by BRENDA team
Kroth, P.G.; Schroers, Y.; Kilian, O.
The peculiar distribution of class I and class II aldolases in diatoms and in red algae
Curr. Genet.
48
389-400
2005
Trieres chinensis, Phaeodactylum tricornutum, Thalassiosira pseudonana
Manually annotated by BRENDA team
Mamczur, P.; Rakus, D.; Gizak, A.; Dus, D.; Dzugaj, A.
The effect of calcium ions on subcellular localization of aldolase-FBPase complex in skeletal muscle
FEBS Lett.
579
1607-1612
2005
Oryctolagus cuniculus
Manually annotated by BRENDA team
Banerjee, P.C.; Vanags, R.I.; Chakrabarty, A.M.; Maitra, P.K.
Fructose 1,6-bisphosphate aldolase activity is essential for synthesis of alginate from glucose by Pseudomonas aeruginosa
J. Bacteriol.
161
458-460
1985
Pseudomonas aeruginosa
Manually annotated by BRENDA team
Elshafei, A.M.; Elsayed, M.A.; Abdel-Fatah, O.M.; Ali, N.H.; Mohamed, L.A.
Some properties of two aldolases in extracts of Aspergillus oryzae
J. Basic Microbiol.
45
31-40
2005
Aspergillus oryzae
Manually annotated by BRENDA team
Izard, T.; Sygusch, J.
Induced fit movements and metal cofactor selectivity of class II aldolases: structure of Thermus aquaticus fructose-1,6-bisphosphate aldolase
J. Biol. Chem.
279
11825-11833
2004
Thermus aquaticus
Manually annotated by BRENDA team
St-Jean, M.; Lafrance-Vanasse, J.; Liotard, B.; Sygusch, J.
High resolution reaction intermediates of rabbit muscle fructose-1,6-bisphosphate aldolase: substrate cleavage and induced fit
J. Biol. Chem.
280
27262-27270
2005
Oryctolagus cuniculus (P00883), Oryctolagus cuniculus
Manually annotated by BRENDA team
Yanez, A.J.; Ludwig, H.C.; Bertinat, R.; Spichiger, C.; Gatica, R.; Berlien, G.; Leon, O.; Brito, M.; Concha, II; Slebe, J.C.
Different involvement for aldolase isoenzymes in kidney glucose metabolism: aldolase B but not aldolase A colocalizes and forms a complex with FBPase
J. Cell. Physiol.
202
743-753
2005
Rattus norvegicus
Manually annotated by BRENDA team
Koeck, T.; Levison, B.; Hazen, S.L.; Crabb, J.W.; Stuehr, D.J.; Aulak, K.S.
Tyrosine nitration impairs mammalian aldolase A activity
Mol. Cell. Proteomics
3
548-557
2004
Oryctolagus cuniculus (P00883)
Manually annotated by BRENDA team
Lal, A.; Plaxton, W.C.; Kayastha, A.M.
Purification and characterization of an allosteric fructose-1,6-bisphosphate aldolase from germinating mung beans (Vigna radiata)
Phytochemistry
66
968-974
2005
Vigna radiata
Manually annotated by BRENDA team
Konishi, H.; Yamane, H.; Maeshima, M.; Komatsu, S.
Characterization of fructose-bisphosphate aldolase regulated by gibberellin in roots of rice seedling
Plant Mol. Biol.
56
839-848
2004
Oryza sativa
Manually annotated by BRENDA team
Hao, J.; Berry, A.
A thermostable variant of fructose bisphosphate aldolase constructed by directed evolution also shows increased stability in organic solvents
Protein Eng. Des. Sel.
17
689-697
2004
Edwardsiella ictaluri, Escherichia coli (P0AB71), Escherichia coli
Manually annotated by BRENDA team
Ramsaywak, P.C.; Labbe, G.; Siemann, S.; Dmitrienko, G.I.; Guillemette, J.G.
Molecular cloning, expression, purification, and characterization of fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis--a novel class II A tetramer
Protein Expr. Purif.
37
220-228
2004
Mycobacterium tuberculosis (P9WQA3), Mycobacterium tuberculosis H37Rv (P9WQA3), Mycobacterium tuberculosis H37Rv
Manually annotated by BRENDA team
Arakaki, T.L.; Pezza, J.A.; Cronin, M.A.; Hopkins, C.E.; Zimmer, D.B.; Tolan, D.R.; Allen, K.N.
Structure of human brain fructose 1,6-(bis)phosphate aldolase: linking isozyme structure with function
Protein Sci.
13
3077-3084
2004
Homo sapiens
Manually annotated by BRENDA team
Anderson, L.E.; Ringenberg, M.R.; Brown, V.K.; Carol, A.A.
Both chloroplastic and cytosolic phosphofructoaldolase isozymes are present in the pea leaf nucleus
Protoplasma
225
235-242
2005
Pisum sativum
Manually annotated by BRENDA team
Lee, J.H.; Bae, J.; Kim, D.; Choi, Y.; Im, Y.J.; Koh, S.; Kim, J.S.; Kim, M.K.; Kang, G.B.; Hong, S.I.; Lee, D.S.; Eom, S.H.
Stereoselectivity of fructose-1,6-bisphosphate aldolase in Thermus caldophilus
Biochem. Biophys. Res. Commun.
347
616-625
2006
Thermus caldophilus (Q703I2), Thermus caldophilus, Thermus caldophilus GK24 (Q703I2), Thermus caldophilus GK24
Manually annotated by BRENDA team
Nandan, D.; Tran, T.; Trinh, E.; Silverman, J.M.; Lopez, M.
Identification of leishmania fructose-1,6-bisphosphate aldolase as a novel activator of host macrophage Src homology 2 domain containing protein tyrosine phosphatase SHP-1
Biochem. Biophys. Res. Commun.
364
601-607
2007
Oryctolagus cuniculus, Leishmania donovani, Leishmania donovani 2S
Manually annotated by BRENDA team
Pezza, J.A.; Stopa, J.D.; Brunyak, E.M.; Allen, K.N.; Tolan, D.R.
Thermodynamic analysis shows conformational coupling and dynamics confer substrate specificity in fructose-1,6-bisphosphate aldolase
Biochemistry
46
13010-13018
2007
Oryctolagus cuniculus (P00883)
Manually annotated by BRENDA team
Lafrance-Vanasse, J.; Sygusch, J.
Carboxy-terminus recruitment induced by substrate binding in eukaryotic fructose bis-phosphate aldolases
Biochemistry
46
9533-9540
2007
Leishmania mexicana (Q9U5N6), Leishmania mexicana
Manually annotated by BRENDA team
Zhang, Y.M.; Liu, J.K.; Shouri, M.R.; Wong, T.Y.
Characterization of a Mn-dependent fructose-1,6-bisphosphate aldolase in Deinococcus radiodurans
Biometals
19
31-37
2006
Deinococcus radiodurans
Manually annotated by BRENDA team
Kakita, H.; Kamishima, H.; Inouye, K.
Purification and some properties of a D-fructose-1,6-bisphosphate aldolase from the red alga, Gracilaria chorda Holmes
Bot. Mar.
49
174-181
2006
Gracilariopsis chorda
-
Manually annotated by BRENDA team
Palop, A.; Rutherford, G.C.; Marquis, R.E.
Inactivation of enzymes within spores of Bacillus megaterium ATCC 19213 by hydroperoxides
Can. J. Microbiol.
44
465-470
1998
Priestia megaterium
Manually annotated by BRENDA team
Rodaki, A.; Young, T.; Brown, A.J.
Effects of depleting the essential central metabolic enzyme fructose-1,6-bisphosphate aldolase on the growth and viability of Candida albicans: implications for antifungal drug target discovery
Eukaryot. Cell
5
1371-1377
2006
Candida albicans
Manually annotated by BRENDA team
Ma, W.; Wei, L.; Wang, Q.; Shi, D.; Chen, H.
Increased activity of the non-regulated enzymes fructose-1,6-bisphosphate aldolase and triosephosphate isomerase in Anabaena sp. strain PCC 7120 increases photosynthetic yield
J. Appl. Phycol.
19
207-213
2007
Oryza sativa
-
Manually annotated by BRENDA team
Ertunga, N.; Colak, A.; Belduz, A.O.; Canakei, S.; Karaoglu, H.; Sandalli, C.
Cloning, expression, purification and characterization of fructose-1,6-bisphosphate aldolase from Anoxybacillus gonensis G2
J. Biochem.
141
817-825
2007
Anoxybacillus gonensis (A1YZ23), Anoxybacillus gonensis G2 (A1YZ23), Anoxybacillus gonensis G2
Manually annotated by BRENDA team
St-Jean, M.; Sygusch, J.
Stereospecific proton transfer by a mobile catalyst in mammalian fructose-1,6-bisphosphate aldolase
J. Biol. Chem.
282
31028-31037
2007
Oryctolagus cuniculus (P00883)
Manually annotated by BRENDA team
Galkin, A.; Kulakova, L.; Melamud, E.; Li, L.; Wu, C.; Mariano, P.; Dunaway-Mariano, D.; Nash, T.E.; Herzberg, O.
Characterization, kinetics, and crystal structures of fructose-1,6-bisphosphate aldolase from the human parasite, Giardia lamblia
J. Biol. Chem.
282
4859-4867
2007
Giardia intestinalis
Manually annotated by BRENDA team
Dax, C.; Duffieux, F.; Chabot, N.; Coincon, M.; Sygusch, J.; Michels, P.A.; Blonski, C.
Selective irreversible inhibition of fructose 1,6-bisphosphate aldolase from Trypanosoma brucei
J. Med. Chem.
49
1499-1502
2006
Oryctolagus cuniculus, Trypanosoma brucei
Manually annotated by BRENDA team
Linke, S.; Goertz, P.; Baader, S.L.; Gieselmann, V.; Siebler, M.; Junghans, U.; Kappler, J.
Aldolase C/zebrin II is released to the extracellular space after stroke and inhibits the network activity of cortical neurons
Neurochem. Res.
31
1297-1303
2006
Homo sapiens, Rattus norvegicus
Manually annotated by BRENDA team
Labbe, G.; Bezaire, J.; de Groot, S.; How, C.; Rasmusson, T.; Yaeck, J.; Jervis, E.; Dmitrienko, G.I.; Guillemette, J.G.
High level production of the Magnaporthe grisea fructose 1,6-bisphosphate aldolase enzyme in Escherichia coli using a small volume bench-top fermentor
Protein Expr. Purif.
51
110-119
2007
Pyricularia grisea
Manually annotated by BRENDA team
De-Simone, S.G.; de Salles, C.M.; Batista e Silva, C.M.; Hasson-Voloch, A.
Purification and amino acid sequence of fructose-1,6-bisphosphate aldolase from the electric organ of Electrophorus electricus (L.)
Z. Naturforsch. C
61
884-888
2007
Electrophorus electricus
Manually annotated by BRENDA team
Sherawat, M.; Tolan, D.R.; Allen, K.N.
Structure of a rabbit muscle fructose-1,6-bisphosphate aldolase A dimer variant
Acta Crystallogr. Sect. D
64
543-550
2008
Oryctolagus cuniculus (P00883), Oryctolagus cuniculus
Manually annotated by BRENDA team
Paez-Valencia, J.; Valencia-Mayoral, P.; Sanchez-Gomez, C.; Contreras-Ramos, A.; Hernandez-Lucas, I.; Martinez-Barajas, E.; Gamboa-DeBuen, A.
Identification of fructose-1,6-bisphosphate aldolase cytosolic class I as an NMH7 MADS domain associated protein
Biochem. Biophys. Res. Commun.
376
700-705
2008
Medicago sativa
Manually annotated by BRENDA team
Mabiala-Bassiloua, C.G.; Zwolinska, M.; Therisod, H.; Sygusch, J.; Therisod, M.
Separate synthesis and evaluation of D-glucitol 1,6-bisphosphate and mannitol bis-phosphate, as competitive inhibitors of fructose bis-phosphate aldolases
Bioorg. Med. Chem. Lett.
18
1735-1737
2008
Oryctolagus cuniculus (P00883), Saccharomyces cerevisiae (P14540), Helicobacter pylori (P56109)
Manually annotated by BRENDA team
Fonvielle, M.; Coincon, M.; Daher, R.; Desbenoit, N.; Kosieradzka, K.; Barilone, N.; Gicquel, B.; Sygusch, J.; Jackson, M.; Therisod, M.
Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics
Chemistry
14
8521-8529
2008
Oryctolagus cuniculus (P00883), Saccharomyces cerevisiae (P14540), Helicobacter pylori (P56109), Mycobacterium tuberculosis (P9WQA3), Mycobacterium tuberculosis H37Rv (P9WQA3)
Manually annotated by BRENDA team
Rukseree, K.; Thammarongtham, C.; Palittapongarnpim, P.
One-step purification and characterization of a fully active histidine-tagged Class II fructose-1,6-bisphosphate aldolase from Mycobacterium tuberculosis
Enzyme Microb. Technol.
43
500-506
2008
Mycobacterium tuberculosis (P9WQA3), Mycobacterium tuberculosis H37Rv (P9WQA3)
-
Manually annotated by BRENDA team
Tabei, Y.; Okada, K.; Makita, N.; Tsuzuki, M.
Light-induced gene expression of fructose 1,6-bisphosphate aldolase during heterotrophic growth in a cyanobacterium, Synechocystis sp. PCC 6803
FEBS J.
276
187-198
2009
Synechocystis sp. PCC 6803 (Q55664)
Manually annotated by BRENDA team
Samland, A.K.; Wang, M.; Sprenger, G.A.
MJ0400 from Methanocaldococcus jannaschii exhibits fructose-1,6-bisphosphate aldolase activity
FEMS Microbiol. Lett.
281
36-41
2008
Methanocaldococcus jannaschii
Manually annotated by BRENDA team
Marques, H.H.; Zouain, C.S.; Torres, C.B.; Oliveira, J.S.; Alves, J.B.; Goes, A.M.
Protective effect and granuloma down-modulation promoted by RP44 antigen a fructose 1,6 bisphosphate aldolase of Schistosoma mansoni
Immunobiology
213
437-446
2008
Schistosoma mansoni (P53442), Schistosoma mansoni
Manually annotated by BRENDA team
Peng, S.Y.; Tsaihong, J.C.; Fan, P.C.; Lee, K.M.
Diagnosis of schistosomiasis using recombinant fructose-1,6-bisphosphate aldolase from a Formosan strain of Schistosoma japonicum
J. Helminthol.
16
1-8
2008
Schistosoma japonicum (Q1HDV3), Schistosoma japonicum, Schistosoma japonicum Formosan (Q1HDV3)
Manually annotated by BRENDA team
Pegan, S.D.; Rukseree, K.; Franzblau, S.G.; Mesecar, A.D.
Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis
J. Mol. Biol.
386
1038-1053
2009
Mycobacterium tuberculosis (P9WQA3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WQA3)
Manually annotated by BRENDA team
Gehring, A.G.; Ezzell, J.L.; Lebherz, H.G.
A selective reaction of fructose bisphosphate aldolase with fluorescein isothiocyanate in chicken muscle extracts
J. Mol. Recognit.
21
137-147
2008
Gallus gallus, Gallus gallus (P53449), Homarus americanus, Lithobates pipiens, Squalus acanthias, Crotalus oreganus helleri, Morone saxatilis, Triticum aestivum (C1J959), Spinacia oleracea (P16096)
Manually annotated by BRENDA team
Peng, S.Y.; Lee, K.M.; Tsaihong, J.C.; Cheng, P.C.; Fan, P.C.
Evaluation of recombinant fructose-1,6-bisphosphate aldolase ELISA test for the diagnosis of Schistosoma japonicum in water buffaloes
Res. Vet. Sci.
85
527-533
2008
Schistosoma japonicum (Q1HDV2), Schistosoma japonicum
Manually annotated by BRENDA team
Kramerova, I.; Kudryashova, E.; Wu, B.; Ottenheijm, C.; Granzier, H.; Spencer, M.J.
Novel role of calpain-3 in the triad-associated protein complex regulating calcium release in skeletal muscle
Hum. Mol. Genet.
17
3271-3280
2008
Mus musculus
Manually annotated by BRENDA team
Galkin, A.; Li, Z.; Li, L.; Kulakova, L.; Pal, L.R.; Dunaway-Mariano, D.; Herzberg, O.
Structural insights into the substrate binding and stereoselectivity of Giardia fructose-1,6-bisphosphate aldolase
Biochemistry
48
3186-3196
2009
Giardia intestinalis (O97447), Giardia intestinalis
Manually annotated by BRENDA team
St-Jean, M.; Blonski, C.; Sygusch, J.
Charge stabilization and entropy reduction of central lysine residues in fructose-bisphosphate aldolase
Biochemistry
48
4528-4537
2009
Oryctolagus cuniculus (P00883)
Manually annotated by BRENDA team
Deng, H.; Cross, S.M.; McGlinchey, R.P.; Hamilton, J.T.; OHagan, D.
In vitro reconstituted biotransformation of 4-fluorothreonine from fluoride ion: application of the fluorinase
Chem. Biol.
15
1268-1276
2008
Streptomyces coelicolor
Manually annotated by BRENDA team
Lowkam, C.; Liotard, B.; Sygusch, J.
Structure of a class I tagatose-1,6-biphosphate aldolase: Study into an apparent loss of stereospecificity
J. Biol. Chem.
285
21143-21152
2010
Oryctolagus cuniculus (P00883)
Manually annotated by BRENDA team
Tochio, T.; Tanaka, H.; Nakata, S.; Hosoya, H.
Fructose-1,6-bisphosphate aldolase A is involved in HaCaT cell migration by inducing lamellipodia formation
J. Dermatol. Sci.
58
123-129
2010
Homo sapiens
Manually annotated by BRENDA team
Tunio, S.A.; Oldfield, N.J.; Berry, A.; Alaaldeen, D.A.; Wooldridge, K.G.; Turner, D.P.
The moonlighting protein fructose-1, 6-bisphosphate aldolase of Neisseria meningitidis: surface localization and role in host cell adhesion
Mol. Microbiol.
76
605-615
2010
Neisseria meningitidis
Manually annotated by BRENDA team
Say, R.F.; Fuchs, G.
Fructose 1,6-bisphosphate aldolase/phosphatase may be an ancestral gluconeogenic enzyme
Nature
464
1077-1081
2010
Cenarchaeum symbiosum, Pyrobaculum neutrophilum, Metallosphaera sedula, Ignicoccus hospitalis
Manually annotated by BRENDA team
Fan, W.; Zhang, Z.; Zhang, Y.
Cloning and molecular characterization of fructose-1,6-bisphosphate aldolase gene regulated by high-salinity and drought in Sesuvium portulacastrum
Plant Cell Rep.
28
975-984
2009
Sesuvium portulacastrum (B5B3T4), Sesuvium portulacastrum
Manually annotated by BRENDA team
Rozova, O.N.; Khmelenina, V.N.; Mustakhimov, I.I.; Reshetnikov, A.S.; Trotsenko, Y.A.
Characterization of recombinant fructose-1,6-bisphosphate aldolase from Methylococcus capsulatus Bath
Biochemistry
75
892-898
2010
Methylococcus capsulatus (Q602L6)
Manually annotated by BRENDA team
Iturrate, L.; Sanchez-Moreno, I.; Oroz-Guinea, I.; Perez-Gil, J.; Garcia-Junceda, E.
Preparation and characterization of a bifunctional aldolase/kinase enzyme: a more efficient biocatalyst for C-C bond formation
Chemistry
16
4018-4030
2010
Staphylococcus carnosus, Staphylococcus carnosus CECT 4491
Manually annotated by BRENDA team
Li, Z.; Liu, Z.; Cho, D.W.; Zou, J.; Gong, M.; Breece, R.M.; Galkin, A.; Li, L.; Zhao, H.; Maestas, G.D.; Tierney, D.L.; Herzberg, O.; Dunaway-Mariano, D.; Mariano, P.S.
Rational design, synthesis and evaluation of first generation inhibitors of the Giardia lamblia fructose-1,6-biphosphate aldolase
J. Inorg. Biochem.
105
509-517
2011
Giardia intestinalis
Manually annotated by BRENDA team
Daher, R.; Coincon, M.; Fonvielle, M.; Gest, P.M.; Guerin, M.E.; Jackson, M.; Sygusch, J.; Therisod, M.
Rational design, synthesis, and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases
J. Med. Chem.
53
7836-7842
2010
Candida albicans, Oryctolagus cuniculus, Helicobacter pylori, Mycobacterium tuberculosis, Yersinia pestis
Manually annotated by BRENDA team
Labbe, G.; de Groot, S.; Rasmusson, T.; Milojevic, G.; Dmitrienko, G.I.; Guillemette, J.G.
Evaluation of four microbial Class II fructose 1,6-bisphosphate aldolase enzymes for use as biocatalysts
Protein Expr. Purif.
80
224-233
2011
Bacillus cereus, Pyricularia grisea, Mycobacterium tuberculosis, Pseudomonas aeruginosa, Bacillus cereus ATCC 10987
Manually annotated by BRENDA team
Mininno, M.; Brugiere, S.; Pautre, V.; Gilgen, A.; Ma, S.; Ferro, M.; Tardif, M.; Alban, C.; Ravanel, S.
Characterization of chloroplastic fructose 1,6-bisphosphate aldolases as lysine-methylated proteins in plants
J. Biol. Chem.
287
21034-21044
2012
Arabidopsis thaliana
Manually annotated by BRENDA team
Labes, A.; Schoenheit, P.
Sugar utilization in the hyperthermophilic, sulfate-reducing archaeon Archaeoglobus fulgidus strain 7324: starch degradation to acetate and CO2 via a modified Embden-Meyerhof pathway and acetyl-CoA synthetase (ADP-forming)
Arch. Microbiol.
176
329-338
2001
Archaeoglobus fulgidus, Archaeoglobus fulgidus 7324
Manually annotated by BRENDA team
Pickl, A.; Johnsen, U.; Schoenheit, P.
Fructose degradation in the haloarchaeon Haloferax volcanii involves a bacterial type phosphoenolpyruvate-dependent phosphotransferase system, fructose-1-phosphate kinase, and class II fructose-1,6-bisphosphate aldolase
J. Bacteriol.
194
3088-3097
2012
Haloferax volcanii (D4GYE0), Haloferax volcanii, Haloferax volcanii DSM 3757 (D4GYE0)
Manually annotated by BRENDA team
Kouril, T.; Esser, D.; Kort J.; Westerhoff, H.V.; Siebers, B.; Snoep, J.L.
Intermediate instability at high temperature leads to low pathway efficiency for an in vitro reconstituted system of gluconeogenesis in Sulfolobus solfataricus
FEBS J.
280
4666-4680
2013
Saccharolobus solfataricus (Q980K6), Saccharolobus solfataricus, Saccharolobus solfataricus P2 (Q980K6)
Manually annotated by BRENDA team
Fushinobu, S.; Nishimasu, H.; Hattori, D.; Song, H.J.; Wakagi, T.
Structural basis for the bifunctionality of fructose-1,6-bisphosphate aldolase/phosphatase
Nature
478
538-541
2011
Sulfurisphaera tokodaii (F9VMT6), Sulfurisphaera tokodaii 7 (F9VMT6)
Manually annotated by BRENDA team
Gardberg, A.; Abendroth, J.; Bhandari, J.; Sankaran, B.; Staker, B.
Structure of fructose bisphosphate aldolase from Bartonella henselae bound to fructose 1,6-bisphosphate
Acta Crystallogr. Sect. F
67
1051-1054
2011
Bartonella henselae (Q8L207), Bartonella henselae
Manually annotated by BRENDA team
Gardberg, A.; Sankaran, B.; Davies, D.; Bhandari, J.; Staker, B.; Stewart, L.
Structure of fructose bisphosphate aldolase from Encephalitozoon cuniculi
Acta Crystallogr. Sect. F
67
1055-1059
2011
Encephalitozoon cuniculi (Q8SSM8), Encephalitozoon cuniculi, Encephalitozoon cuniculi GB-M1 (Q8SSM8)
Manually annotated by BRENDA team
Pegan, S.D.; Rukseree, K.; Capodagli, G.C.; Baker, E.A.; Krasnykh, O.; Franzblau, S.G.; Mesecar, A.D.
Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis
Biochemistry
52
912-925
2013
Mycobacterium tuberculosis (P9WQA3), Mycobacterium tuberculosis
Manually annotated by BRENDA team
Ciesla, M.; Mierzejewska, J.; Adamczyk, M.; Farrants, A.K.; Boguta, M.
Fructose bisphosphate aldolase is involved in the control of RNA polymerase III-directed transcription
Biochim. Biophys. Acta
1843
1103-1110
2014
Saccharomyces cerevisiae
Manually annotated by BRENDA team
Prasad, C.S.; Gupta, S.; Kumar, H.; Tiwari, M.
Evolutionary and functional analysis of fructose bisphosphate aldolase of plant parasitic nematodes
Bioinformation
9
1-8
2013
Heterodera glycines (Q9GPK1), Heterodera glycines
Manually annotated by BRENDA team
Li, Z.; Cai, L.; Wei, M.; Wang, P.G.
One-pot four-enzyme synthesis of ketoses with fructose 1,6-bisphosphate aldolases from Staphylococcus carnosus and rabbit muscle
Carbohydr. Res.
357
143-146
2012
Oryctolagus cuniculus, Staphylococcus carnosus
Manually annotated by BRENDA team
Gutierrez, M.; Parella, T.; Joglar, J.; Bujons J.; Claps P.
Structure-guided redesign of D-fructose-6-phosphate aldolase from E. coli: remarkable activity and selectivity towards acceptor substrates by two-point mutation
Chem. Commun. (Camb. )
47
5762-5764
2011
Escherichia coli
Manually annotated by BRENDA team
Krishnan, G.; Altekar, W.
An unusual class I (Schiff base) fructose-1,6-bisphosphate aldolase from the halophilic archaebacterium Haloarcula vallismortis
Eur. J. Biochem.
195
343-350
1991
Haloarcula vallismortis
Manually annotated by BRENDA team
Yu, J.P.; Ladapo, J.; Whitman, W.B.
Pathway of glycogen metabolism in Methanococcus maripaludis
J. Bacteriol.
176
325-332
1994
Methanococcus maripaludis
Manually annotated by BRENDA team
de la Paz Santangelo, M.; Gest, P.M.; Guerin, M.E.; Coincon, M.; Pham, H.; Ryan, G.; Puckett, S.E.; Spencer, J.S.; Gonzalez-Juarrero, M.; Daher, R.; Lenaerts, A.J.; Schnappinger, D.; Therisod, M.; Ehrt, S.; Sygusch, J.; Jackson, M.
Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli
J. Biol. Chem.
286
40219-40231
2011
Mycobacterium tuberculosis (P9WQA3), Mycobacterium tuberculosis
Manually annotated by BRENDA team
Uematsu, K.; Suzuki, N.; Iwamae, T.; Inui, M.; Yukawa, H.
Increased fructose 1,6-bisphosphate aldolase in plastids enhances growth and photosynthesis of tobacco plants
J. Exp. Bot.
63
3001-3009
2012
Arabidopsis thaliana
Manually annotated by BRENDA team
D'Souza, S.E.; Altekar, W.
A class II fructose-1,6-bisphosphate aldolase from a halophilic archaebacterium Haloferax mediterranei
J. Gen. Appl. Microbiol.
44
235-241
1998
Haloferax mediterranei, Haloferax mediterranei DSM 1411
Manually annotated by BRENDA team
Labbe, G.; Krismanich, A.P.; de Groot, S.; Rasmusson, T.; Shang, M.; Brown, M.D.; Dmitrienko, G.I.; Guillemette, J.G.
Development of metal-chelating inhibitors for the class II fructose 1,6-bisphosphate (FBP) aldolase
J. Inorg. Biochem.
112
49-58
2012
Bacillus cereus, Mycobacterium tuberculosis, Pseudomonas aeruginosa, Pyricularia grisea
Manually annotated by BRENDA team
Moon, S.; Shin, D.; Kim, B.; Byun, M.
Putative fructose-1,6-bisphosphate aldolase 1 (AtFBA1) affects stress tolerance in yeast and Arabidopsis
J. Plant Biotechnol.
39
106-113
2012
Arabidopsis thaliana
-
Manually annotated by BRENDA team
Stolzenberger, J.; Lindner, S.N.; Wendisch, V.F.
The methylotrophic Bacillus methanolicus MGA3 possesses two distinct fructose 1,6-bisphosphate aldolases
Microbiology
159
1770-1781
2013
Bacillus methanolicus, Bacillus methanolicus (I3EBM6), Bacillus methanolicus MGA3, Bacillus methanolicus MGA3 (I3EBM6)
Manually annotated by BRENDA team
Macomber, L.; Elsey, S.P.; Hausinger, R.P.
Fructose-1,6-bisphosphate aldolase (class II) is the primary site of nickel toxicity in Escherichia coli
Mol. Microbiol.
82
1291-1300
2011
Escherichia coli
Manually annotated by BRENDA team
Du, J.; Say, R.F.; L, W.; Fuchs, G.; Einsle, O.
Active-site remodelling in the bifunctional fructose-1,6-bisphosphate aldolase/phosphatase
Nature
478
534-537
2011
Pyrobaculum neutrophilum (B1YAL1), Pyrobaculum neutrophilum, Pyrobaculum neutrophilum DSM 2338 (B1YAL1)
Manually annotated by BRENDA team
Guo, W.; Zou, L.F.; Li,Y.R.; Cui, Y.P.; Ji, Z.Y.; Cai, L.L.; Zou, H.S.; Hutchins, W.C.; Yang, C.H.; Chen, G.Y.
Fructose-bisphophate aldolase exhibits functional roles between carbon metabolism and the hrp system in rice pathogen Xanthomonas oryzae pv. oryzicola
PLoS One
7
e31855
2012
Xanthomonas oryzae pv. oryzicola
Manually annotated by BRENDA team
Dawson, N.J.; Biggar, K.K.; Storey, K.B.
Characterization of fructose-1,6-bisphosphate aldolase during anoxia in the tolerant turtle, Trachemys scripta elegans: an assessment of enzyme activity, expression and structure
PLoS ONE
8
e68830
2013
Trachemys scripta elegans
Manually annotated by BRENDA team
Boucher, L.E.; Bosch, J.
Structure of Toxoplasma gondii fructose-1,6-bisphosphate aldolase
Acta Crystallogr. Sect. F
70
1186-1192
2014
Toxoplasma gondii (B9PW35), Toxoplasma gondii, Toxoplasma gondii ATCC 50861 (B9PW35)
Manually annotated by BRENDA team
Zhang, L.; Guo, Z.; Huang, J.; Liu, M.; Wang, Y.; Ji, C.
Expression, purification, crystallization and preliminary X-ray crystallographic analysis of fructose-1,6-bisphosphate aldolase from Escherichia coli
Acta Crystallogr. Sect. F
70
1376-1379
2014
Escherichia coli
Manually annotated by BRENDA team
Shams, F.; Oldfield, N.J.; Wooldridge, K.G.; Turner, D.P.
Fructose-1,6-bisphosphate aldolase (FBA)-a conserved glycolytic enzyme with virulence functions in bacteria 'ill met by moonlight
Biochem. Soc. Trans.
42
1792-1795
2014
Streptococcus pneumoniae, Mycobacterium tuberculosis, Neisseria meningitidis, Streptococcus suis, Streptococcus suis SS9, Streptococcus pneumoniae WU2
Manually annotated by BRENDA team
Capodagli, G.C.; Lee, S.A.; Boehm, K.J.; Brady, K.M.; Pegan, S.D.
Structural and functional characterization of methicillin-resistant Staphylococcus aureus's class IIb fructose 1,6-bisphosphate aldolase
Biochemistry
53
7604-7614
2014
Staphylococcus aureus (Q5HE75), Staphylococcus aureus, Staphylococcus aureus COL (Q5HE75)
Manually annotated by BRENDA team
Tittmann, K.
Sweet siblings with different faces the mechanisms of FBP and F6P aldolase, transaldolase, transketolase and phosphoketolase revisited in light of recent structural data
Bioorg. Chem.
57
263-280
2014
Thermoproteus tenax
Manually annotated by BRENDA team
Chaves, E.G.; Weber, S.S.; Bao, S.N.; Pereira, L.A.; Bailao, A.M.; Borges, C.L.; Soares, C.M.
Analysis of Paracoccidioides secreted proteins reveals fructose 1,6-bisphosphate aldolase as a plasminogen-binding protein
BMC Microbiol.
15
53
2015
Paracoccidioides lutzii (Q96UH7), Paracoccidioides lutzii, Paracoccidioides lutzii ATCC MYA-826 (Q96UH7), Paracoccidioides lutzii Pb01 (Q96UH7)
Manually annotated by BRENDA team
Roslan, H.; Hossain, M.; Gerunsin, J.
Molecular and 3d-structural characterization of fructose-1,6-bisphosphate aldolase derived from Metroxylon sagu
Braz. Arch. Biol. Technol.
60
e17160108
2017
Metroxylon sagu
-
Manually annotated by BRENDA team
Roldan, R.; Sanchez-Moreno, I.; Scheidt, T.; Helaine, V.; Lemaire, M.; Parella, T.; Clapes, P.; Fessner, W.D.; Guerard-Helaine, C.
Breaking the dogma of aldolase specificity simple aliphatic ketones and aldehydes are nucleophiles for fructose-6-phosphate aldolase
Chemistry
23
5005-5009
2017
Escherichia coli (P0AB71)
Manually annotated by BRENDA team
Aziz, I.; Rashid, N.; Ashraf, R.; Bashir, Q.; Imanaka, T.; Akhtar, M.
Pcal_0111, a highly thermostable bifunctional fructose-1,6-bisphosphate aldolase/phosphatase from Pyrobaculum calidifontis
Extremophiles
21
513-521
2017
Pyrobaculum calidifontis (A3MSD2), Pyrobaculum calidifontis, Pyrobaculum calidifontis JCM 11548 (A3MSD2), Pyrobaculum calidifontis VA1 (A3MSD2), Pyrobaculum calidifontis JGM 11548 (A3MSD2)
Manually annotated by BRENDA team
Sun, Z.; Shen, B.; Wu, H.; Zhou, X.; Wang, Q.; Xiao, J.; Zhang, Y.
The secreted fructose 1,6-bisphosphate aldolase as a broad spectrum vaccine candidate against pathogenic bacteria in aquaculture
Fish Shellfish Immunol.
46
638-647
2015
Aeromonas hydrophila, Aeromonas hydrophila (A0KGD4), Edwardsiella tarda, Edwardsiella tarda (D0ZEE4), Vibrio alginolyticus, Vibrio alginolyticus (A7MTQ6), Vibrio anguillarum, Vibrio anguillarum (D0ZEE4), Vibrio harveyi, Vibrio campbellii (A7MTQ6), Vibrio harveyi ATCC BAA-1116, Vibrio anguillarum MVM425, Vibrio anguillarum MVM425 (D0ZEE4), Edwardsiella tarda EIB202, Edwardsiella tarda EIB202 (D0ZEE4), Vibrio alginolyticus 12G01, Vibrio alginolyticus 12G01 (A7MTQ6), Vibrio campbellii ATCC BAA-1116 (A7MTQ6), Aeromonas hydrophila ATCC7699, Aeromonas hydrophila ATCC 7699 (A0KGD4)
Manually annotated by BRENDA team
Elhaik Goldman, S.; Dotan, S.; Talias, A.; Lilo, A.; Azriel, S.; Malka, I.; Portnoi, M.; Ohayon, A.; Kafka, D.; Ellis, R.; Elkabets, M.; Porgador, A.; Levin, D.; Azhari, R.; Swiatlo, E.; Ling, E.; Feldman, G.; Tal, M.; Dagan, R.; Mizrachi Nebenzahl, Y.
Streptococcus pneumoniae fructose-1,6-bisphosphate aldolase, a protein vaccine candidate, elicits Th1/Th2/Th17-type cytokine responses in mice
Int. J. Mol. Med.
37
1127-1138
2016
Streptococcus pneumoniae, Streptococcus pneumoniae serotype 3, Streptococcus pneumoniae serotype 3 WU2, Streptococcus pneumoniae WU2
Manually annotated by BRENDA team
Kawai, K.; Uemura, M.; Munakata, K.; Takahashi, H.; Haraguchi, N.; Nishimura, J.; Hata, T.; Matsuda, C.; Ikenaga, M.; Murata, K.; Mizushima, T.; Yamamoto, H.; Doki, Y.; Mori, M.
Fructose-bisphosphate aldolase A is a key regulator of hypoxic adaptation in colorectal cancer cells and involved in treatment resistance and poor prognosis
Int. J. Oncol.
50
525-534
2017
Homo sapiens (P04075), Homo sapiens
Manually annotated by BRENDA team
Heron, P.W.; Sygusch, J.
Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases
J. Biol. Chem.
292
19849-19860
2017
Toxoplasma gondii (Q8I8I2)
Manually annotated by BRENDA team
Han, X.; Zhu, X.; Hong, Z.; Wei, L.; Ren, Y.; Wan, F.; Zhu, S.; Peng, H.; Guo, L.; Rao, L.; Feng, L.; Wan, J.
Structure-based rational design of novel inhibitors against fructose-1,6-bisphosphate aldolase from Candida albicans
J. Chem. Inf. Model.
57
1426-1438
2017
Candida albicans (Q9URB4), Candida albicans, Candida albicans ATCC MYA-2876 (Q9URB4)
Manually annotated by BRENDA team
Tonkin, M.L.; Halavaty, A.S.; Ramaswamy, R.; Ruan, J.; Igarashi, M.; Ngo, H.M.; Boulanger, M.J.
Structural and functional divergence of the aldolase fold in Toxoplasma gondii
J. Mol. Biol.
427
840-852
2015
Toxoplasma gondii (A0A125YGE6), Toxoplasma gondii, Toxoplasma gondii ATCC 50611 (A0A125YGE6)
Manually annotated by BRENDA team
Shams, F.; Oldfield, N.J.; Lai, S.K.; Tunio, S.A.; Wooldridge, K.G.; Turner, D.P.
Fructose-1,6-bisphosphate aldolase of Neisseria meningitidis binds human plasminogen via its C-terminal lysine residue
MicrobiologyOpen
5
340-350
2016
Neisseria meningitidis
Manually annotated by BRENDA team
Ziveri, J.; Tros, F.; Guerrera, I.C.; Chhuon, C.; Audry, M.; Dupuis, M.; Barel, M.; Korniotis, S.; Fillatreau, S.; Gales, L.; Cahoreau, E.; Charbit, A.
The metabolic enzyme fructose-1,6-bisphosphate aldolase acts as a transcriptional regulator in pathogenic Francisella
Nat. Commun.
8
853
2017
Francisella tularensis subsp. novicida, Francisella tularensis subsp. novicida (A0Q7I9), Francisella tularensis subsp. novicida U112, Francisella tularensis subsp. novicida U112 (A0Q7I9)
Manually annotated by BRENDA team
Zhang, C.S.; Hawley, S.A.; Zong, Y.; Li, M.; Wang, Z.; Gray, A.; Ma, T.; Cui, J.; Feng, J.W.; Zhu, M.; Wu, Y.Q.; Li, T.Y.; Ye, Z.; Lin, S.Y.; Yin, H.; Piao, H.L.; Hardie, D.G.; Lin, S.C.
Fructose-1,6-bisphosphate and aldolase mediate glucose sensing by AMPK
Nature
548
112-116
2017
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Prompipak, J.; Senawong, T.; Jokchaiyaphum, K.; Siriwes, K.; Nuchadomrong, S.; Laha, T.; Sripa, B.; Senawong, G.
Characterization and localization of Opisthorchis viverrini fructose-1,6-bisphosphate aldolase
Parasitol. Int.
66
413-418
2017
Opisthorchis viverrini
Manually annotated by BRENDA team
Hou, Q.; Sheng, X.; Liu, Y.
QM/MM studies of the mechanism of unusual bifunctional fructose-1,6-bisphosphate aldolase/phosphatase
Phys. Chem. Chem. Phys.
16
11366-11373
2014
Sulfurisphaera tokodaii (F9VMT6), Sulfurisphaera tokodaii DSM 16993 (F9VMT6)
Manually annotated by BRENDA team
Cai, B.; Li, Q.; Liu, F.; Bi, H.; Ai, X.
Decreasing fructose-1,6-bisphosphate aldolase activity reduces plant growth and tolerance to chilling stress in tomato seedlings
Physiol. Plant.
163
247-258
2018
Solanum lycopersicum
Manually annotated by BRENDA team
Mendonca, M.; Moreira, G.M.; Conceicao, F.R.; Hust, M.; Mendonca, K.S.; Moreira, A.N.; Franca, R.C.; da Silva, W.P.; Bhunia, A.K.; Aleixo, J.A.
Fructose 1,6-bisphosphate aldolase, a novel immunogenic surface protein on Listeria species
PLoS ONE
11
e0160544
2016
Listeria innocua, Listeria monocytogenes, Listeria seeligeri, Listeria ivanovii, Listeria welshimeri, Listeria grayi, Listeria marthii, Listeria rocourtiae, Listeria monocytogenes EGD (Q8Y498), Listeria monocytogenes 2540, Listeria grayi 19120, Listeria monocytogenes 2479, Listeria monocytogenes 19118, Listeria monocytogenes 19116, Listeria monocytogenes 19114, Listeria innocua Li01, Listeria seeligeri Ls02, Listeria monocytogenes V7, Listeria monocytogenes F4244, Listeria monocytogenes F4260, Listeria monocytogenes EGD ATCC BAA-679 (Q8Y498), Listeria monocytogenes Murray B, Listeria ivanovii SE98, Listeria monocytogenes 2482, Listeria rocourtiae 109804, Listeria monocytogenes 19113, Listeria monocytogenes 19117, Listeria marthii BAA-1595, Listeria seeligeri 3954, Listeria innocua F4248, Listeria welshimeri 35897
Manually annotated by BRENDA team
Zeng, Y.; Tan, X.; Zhang, L.; Jiang, N.; Cao, H.
Identification and expression of fructose-1,6-bisphosphate aldolase genes and their relations to oil content in developing seeds of tea oil tree (Camellia oleifera)
PLoS ONE
9
e107422
2014
Camellia oleifera, Camellia oleifera (F8V2Y3), Camellia oleifera (L0HLF8), Camellia oleifera (L0HNG6), Camellia oleifera (L0HP42)
Manually annotated by BRENDA team
Droppelmann, C.A.; Saez, D.E.; Asenjo, J.L.; Yanez, A.J.; Garcia-Rocha, M.; Concha, I.I.; Grez, M.; Guinovart, J.J.; Slebe, J.C.
A new level of regulation in gluconeogenesis metabolic state modulates the intracellular localization of aldolase B and its interaction with liver fructose-1,6-bisphosphatase
Biochem. J.
472
225-237
2015
Rattus norvegicus (P00884), Rattus norvegicus Wistar (P00884)
Manually annotated by BRENDA team
Zhang, L.; Guo, Z.; Huang, J.; Liu, M.; Wang, Y.; Ji, C.
Expression, purification, crystallization and preliminary X-ray crystallographic analysis of fructose-1,6-bisphosphate aldolase from Escherichia coli
Acta Crystallogr. F Struct. Biol. Commun.
70
1376-1379
2014
Escherichia coli
Manually annotated by BRENDA team