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Disease on EC 4.1.2.13 - fructose-bisphosphate aldolase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
4-hydroxy-2-oxoglutarate aldolase deficiency
Primary hyperoxaluria type III-a model for studying perturbations in glyoxylate metabolism.
Acidosis
Severe acidosis in a neonate with pulmonary valve stenosis: a possible stress inducer of a fatal syndrome of fructose-1, 6-biphosphatase and aldolase deficiency.
Acute Kidney Injury
Tsutsugamushi infection-associated acute rhabdomyolysis and acute renal failure.
[Fructose-1,6-diphosphate aldolase and ketose-1-phosphate aldolase isoenzyme spectra in the kidneys normally and in uranyl acetate poisoning]
Adenocarcinoma
Aldolase A promotes epithelial-mesenchymal transition to increase malignant potentials of cervical adenocarcinoma.
Aldolase B Overexpression is Associated with Poor Prognosis and Promotes Tumor Progression by Epithelial-Mesenchymal Transition in Colorectal Adenocarcinoma.
High Expression of Aldolase B Confers a Poor Prognosis for Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy.
Overexpression of aldolase A and cytokeratin 19 in ovine pulmonary adenocarcinoma.
Proteomic analysis of pancreatic ductal adenocarcinoma compared with normal adjacent pancreatic tissue and pancreatic benign cystadenoma.
Skeletal muscle metabolism in mice bearing adenocarcinoma. I. Histochemical alterations in glycogenolytic, glycolytic, lipolytic and oxidative metabolism.
adenylate kinase deficiency
Red cell enzymopathies as a model of inborn errors of metabolism.
Alcohol Withdrawal Delirium
Activity of aldolase, aminotransferases, phosphohexoisomerase and ceruloplasmin in the course of delirium tremens.
[Activity of aldolase, aminotransferases, phosphohexoisomerase and ceruloplasmin in the course of delirium tremens]
[Aldolase distribution in plasma and erythrocytes during delirium tremens.]
Alopecia
Fructose-1,6-bisphosphate aldolase A levels decrease in hair keratinocytes during androgenetic alopecia.
Alzheimer Disease
Activities of key glycolytic enzymes in the brains of patients with Alzheimer's disease.
Codon 129 polymorphism specific cerebrospinal fluid proteome pattern in sporadic creutzfeldt-jakob disease and the implication of glycolytic enzymes in prion-induced pathology.
Identification of aldolase as a target antigen in Alzheimer's disease.
Amyotrophic Lateral Sclerosis
Investigations on enzyme activity in the serum and CSF of patients with neuromuscular diseases.
Anaphylaxis
[A CASE OF FOOD-DEPENDENT EXERCISE-INDUCED ANAPHYLAXIS BY SHRIMP: FRUCTOSE 1, 6- BISPHOSPHATE ALDOLASE IS SUPPOSED AS CAUSATIVE COMPONENT DESPITE NEGATIVE ALLERGEN-SPECIFIC IGE TEST (IMMUNOCAP®)].
[Changes in the activity of aldolase, glutamic-oxaloacetic and glutamic-pyruvic transaminases of the blood serum in anaphylactic shock]
[Changes in the concentration of adenosine triphosphate and in the activities of fructose-1,6-diphosphate aldolase and lactate dehydrogenase in the postmitochondrial supernatant of lung homogenate of guinea pigs after anaphylactic shock]
Anemia
Erythropoiesis, red-cell creatine and plasma aldolase activity in anaemia in the rabbit and man.
Myocardial vascular and metabolic adaptations in chronically anemic fetal sheep.
[Clinical and experimental studies on blood aldolase in children. III. Aldolase activity in erythrocytes and plasma in experimental hemolytic anemia with a remarkable reticulocytosis.]
Anemia, Aplastic
[Clinical and experimental studies on aldolase and its isoenzymes in leukemia and allied hematological disorders (author's transl)]
Anemia, Hemolytic
A syndrome of mental retardation, short stature, hemolytic anemia, delayed puberty, and abnormal facial appearance: similarities to a report of aldolase A deficiency.
A thermolabile aldolase A mutant causes fever-induced recurrent rhabdomyolysis without hemolytic anemia.
Age-related red cell enzymes in children with transient erythroblastopenia of childhood and with hemolytic anemia.
Aldolase A deficiency: Report of new cases and literature review.
Glycogen storage disease type XII; an ultra rare cause of hemolytic anemia and rhabdomyolysis: one new case report.
Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr).
Human aldolase A deficiency associated with a hemolytic anemia: thermolabile aldolase due to a single base mutation.
Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function.
Human aldolase A of a hemolytic anemia patient with Asp-128----Gly substitution: characteristics of an enzyme generated in E. coli transfected with the expression plasmid pHAAD128G.
Red cell aldolase deficiency and hemolytic anemia: a new syndrome.
Snapshots of catalysis: the structure of fructose-1,6-(bis)phosphate aldolase covalently bound to the substrate dihydroxyacetone phosphate.
Structure of a rabbit muscle fructose-1,6-bisphosphate aldolase A dimer variant.
Studies with type I aldolase to understand fructose intolerance and combat parasitic disease.
Subunit interface mutants of rabbit muscle aldolase form active dimers.
Two cases of red cell aldolase deficiency associated with hereditary hemolytic anemia in a Japanese family.
Unraveling the structural and functional features of an aldolase A mutant involved in the hemolytic anemia and severe rhabdomyolysis reported in a child.
[Aldolase]
[Anesthesia for a patient with red cell aldolase deficiency]
[Clinical and experimental studies on blood aldolase in children. III. Aldolase activity in erythrocytes and plasma in experimental hemolytic anemia with a remarkable reticulocytosis.]
[Enzymatic activity of glycolysis in the erythrocytes in the course of an experimental hemolytic anemia: phosphoglucomutase, aldolase and enolase activity.]
Anemia, Hemolytic, Congenital
Human aldolase A deficiency associated with a hemolytic anemia: thermolabile aldolase due to a single base mutation.
Two cases of red cell aldolase deficiency associated with hereditary hemolytic anemia in a Japanese family.
[Anesthesia for a patient with red cell aldolase deficiency]
Anemia, Hemolytic, Congenital Nonspherocytic
Two cases of red cell aldolase deficiency associated with hereditary hemolytic anemia in a Japanese family.
Angina Pectoris
[IMPORTANCE OF DETERMINING THE ACTIVITY OF GLUTAMIC OXALACETIC TRANSAMINASE, ALDOLASE AND C-REACTIVE PROTEIN FOR THE DIFFERENTIATION OF MACRO- AND MICROFOCAL MYOCARDIAL INFARCT AND STENOCARDIA.]
Anthracosilicosis
[Level of lactic acid, activity of lactate dehydrogenase and 1,6-fructosediphosphate aldolase in the blood serum of patients with anthracosilicosis]
Appendicitis
[On the clinical significance of the determination of aldolase and transaminase activity in acute cholecystitis and acute appendicitis]
[The level of sugar, diastase and aldolase in the exudate of the abdominal cavity in acute appendicitis]
Arsenic Poisoning
[Changes induced in serum levels of aldolase and lactic dehydrogenase by experimental mercury and arsenic poisoning.]
Arteriosclerosis
[Activity of aldolase in the blood serum and erythrocytes in patients with hypertension and arteriosclerosis]
Arthralgia
Classification criteria for polymyositis and dermatomyositis.
Eosinophilia-myalgia syndrome. Results of national surveillance.
Arthritis
Classification criteria for polymyositis and dermatomyositis.
[Coxsackie virus infection. Associated with myositis and polyarthritis]
[Evaluation of the muscle origin of serum aldolase in chronic polyarthritis.]
Arthritis, Rheumatoid
Effect of ergometric exercise on the activity in the serum of creatine phosphokinase, glutamate-oxaloacetate transminase and aldolase in rheumatoid arthritis.
Serum samples of patients with rheumatoid arthritis contain a specific autoantibody to "denatured" aldolase A in the osteoblast-like cell line, MG-63.
Arthrogryposis
Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme function.
Asthma
Patterns of serum aspartic and alanine aminotransferase as well as aldolase activity in attacks of bronchial asthma, paroxysmal tachycardia and pulmonary edema.
[Pattern of activity of aspartic aminotransferase, alanine aminotransferase and aldolase in attacks of bronchial asthma, paroxysmal tachycardia and pulmonary edema]
[THE ROLE OF HEPATIC INSUFFICIENCY IN INFANTILE BRONCHIAL ASTHMA. II. THE SERUM LEVELS OF ALDOLASE. PRELIMINARY NOTE.]
Astrocytoma
An immunohistochemical study of aldolase C in normal and neoplastic nervous tissues.
Atherosclerosis
[Aldolase and -glycerolphosphate and 3-phosphoglycerol aldehyde dehydrogenase activity of rabbit muscles in experimental atherosclerosis]
[Amino acid composition and subunit structure of rabbit muscle aldolase in experimental atherosclerosis]
[Content of the nonsaponifying substances in crystalline fructosediphosphate aldolase from the muscles of rabbits normally and in atherosclerosis]
[Properties of fructose-1,6-diphosphate aldolase from human muscles in atherosclerosis]
[Structural differences of C-terminal fragment of the alpha-subunits of rabbit muscle aldolase in normal animals and in experimental atherosclerosis]
Autoimmune Diseases
Impact of Autoantibodies against Glycolytic Enzymes on Pathogenicity of Autoimmune Retinopathy and Other Autoimmune Disorders.
beta-Thalassemia
[Study of enzymatic activities in the erythrocytes and platelets of subjects with Mediterranean anemia. II. Aldolase activity of thalassemic platelets]
Bile Duct Neoplasms
miR-122-5p Inhibits the Proliferation, Invasion and Growth of Bile Duct Carcinoma Cells by Targeting ALDOA.
Biliary Tract Diseases
[Ceruloplasmin, cholinesterase and aldolase activity in children with biliary tract disease]
Birth Injuries
[Hexokinase and aldolase activity in the healthy newborn, in asphyxia and in birth injuries]
Blister
[Aldolase activity in blood & blister fluid in dermatoses.]
Brain Injuries
Intranasal wnt-3a alleviates neuronal apoptosis in early brain injury post subarachnoid hemorrhage via the regulation of wnt target PPAN mediated by the moonlighting role of aldolase C.
Brain Ischemia
Why do Purkinje cells die so easily after global brain ischemia? Aldolase C, EAAT4, and the cerebellar contribution to posthypoxic myoclonus.
Brain Neoplasms
Aldolase C in brain tumour.
Aldolase C in experimental brain tumor.
Aldolase isozyme patterns of human brain tumors.
[Aldolase isoenzymes in brain tumor]
[Aldolase isozymes in brain tumors studied by disc electrophoresis (author's transl)]
Breast Diseases
Glycolytic enzymes in breast cancer, benign breast disease and normal breast tissue.
Breast Neoplasms
Aldolase isoenzyme patterns during human ontogeny and in lung, kidney and breast cancer.
BCDIN3D RNA methyltransferase stimulates Aldolase C expression and glycolysis through let-7 microRNA in breast cancer cells.
Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1? Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target.
Glycolytic enzyme activities in breast cancer metastases.
Glycolytic enzymes in breast cancer, benign breast disease and normal breast tissue.
Heterogeneity of glycolytic enzyme activity and isozyme composition of pyruvate kinase in breast cancer.
Proteome analysis of schizophrenia patients Wernicke's area reveals an energy metabolism dysregulation.
Serum aldolase and hexokinase activities in breast carcinoma.
Serum glycolytic enzymes in breast carcinoma.
[On the behavior of some enzymatic activities of neoplastic tissues (glutamic-oxalacetic transaminases, glutamic-pyruvic transaminases, aldolase, lactic hydrogenase and malic dehydrogenase). I. Breast neoplasms.]
Bronchitis
[Enzymatic studies of avian infectious bronchitis. Behavior of some enzymes (GOT, GPT, aldolase, LDH, FAc, FAl, LAP and SDH) in the amino-allantoid fluids of normal and infected embryonated eggs]
Candidemia
Diagnostic value of immunoglobulin G antibodies against Candida enolase and fructose-bisphosphate aldolase for candidemia.
Candidiasis
Phage vaccines displaying YGKDVKDLFDYAQE epitope induce protection against systemic candidiasis in mouse model.
Synthetic glycopeptide vaccines combining beta-mannan and peptide epitopes induce protection against candidiasis.
Carcinogenesis
Aldolase A as a prognostic factor and mediator of progression via inducing epithelial-mesenchymal transition in gastric cancer.
Aldolase A promotes proliferation and G1/S transition via the EGFR/MAPK pathway in non-small cell lung cancer.
An immunochemical and immunohistochemical study of aldolase isozymes in renal cell carcinoma.
C/D-Box Snord105b Promotes Tumorigenesis in Gastric Cancer via ALDOA/C-Myc Pathway.
Changes in the activities of glucose-6-phosphatase, aldolase, and alkaline phosphatase during azo-dye carcinogenesis.
Changes of aldolase A and B messenger RNA levels in rat liver during azo-dye-induced hepatocarcinogenesis.
Fructose-1,6-Bisphosphate Aldolase B Depletion Promotes Hepatocellular Carcinogenesis Through Activating Insulin Receptor Signaling and Lipogenesis.
Fructose-bisphosphate aldolase a is a potential metastasis-associated marker of lung squamous cell carcinoma and promotes lung cell tumorigenesis and migration.
High expression of ALDOA and DDX5 are associated with poor prognosis in human colorectal cancer.
Identification of four isoforms of aldolase B down-regulated in hepatocellular carcinoma tissues by means of two-dimensional Western blotting.
Isozyme pattern of fructose diphosphate aldolase during hepatocarcinogenesis induced by 2-acetylaminofluorene in rat liver.
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
Modifications of the expression of liver-specific and non-specific messenger RNAs during azo-dye hepatocarcinogenesis.
Multiple elements for negative regulation of the rat catalase gene expression in dedifferentiated hepatoma cells.
Noncoordinate changes in the steady-state mRNA expressed from aldolase A and aldolase C genes during differentiation of chicken myoblasts.
Proteomic characterization of idiopathic pulmonary fibrosis patients: stable versus acute exacerbation.
[Rat aldolase isozyme gene: structure and expression in the liver during both fetal development and chemical carcinogenesis]
[Studies on aldolase isozymes in liver tissue in carcinogenesis induced by azo dyes]
Carcinoid Tumor
Aldolase C in neuroendocrine tumors: an immunohistochemical study.
Carcinoma
Aldolase A isoenzyme levels in serum and tissues of patients with liver diseases.
Aldolase A promotes proliferation and G1/S transition via the EGFR/MAPK pathway in non-small cell lung cancer.
Aldolase C in neuroendocrine tumors: an immunohistochemical study.
Aldolase isoenzymes in liver cirrhosis and primary liver cell cancer.
An immunochemical and immunohistochemical study of aldolase isozymes in renal cell carcinoma.
Clinical significance of serum lactate dehydrogenase, phosphohexose isomerase, aldolase and hexokinase in prostatic carcinoma.
Combined use of serum enzyme levels as tumor markers in cervical carcinoma patients.
Comparison of aldolase isozymes in placenta, HeLa cells, and human fibroblast cultures.
Detachment of glycolytic enzymes from cytoskeleton of Lewis lung carcinoma and colon adenocarcinoma cells induced by clotrimazole and its correlation to cell viability and morphology.
Diagnostic and prognostic significance of serum phosphohexose isomerase, aldolase and hexokinase in carcinoma cervix.
Distinctive gene expression profiles by cDNA microarrays in endometrioid and serous carcinomas of the endometrium.
Elevated levels of serum aldolase A in patients with renal cell carcinoma.
Expression of aldolase C isozyme in renal cell carcinoma.
Fructose-bisphosphate aldolase a is a potential metastasis-associated marker of lung squamous cell carcinoma and promotes lung cell tumorigenesis and migration.
High expression of Aldolase A predicts poor survival in patients with clear-cell renal cell carcinoma.
High expression of fructose-bisphosphate aldolase A induces progression of renal cell carcinoma.
Human aldolase B serum levels: a marker of liver injury.
Human aldolase B subunit-specific radioimmunoassay.
miR-122-5p Inhibits the Proliferation, Invasion and Growth of Bile Duct Carcinoma Cells by Targeting ALDOA.
Significance of serum phosphohexose isomerase, hexokinase and aldolase in carcinoma ovary.
Studies on isoenzymes in relation to cancer. II: Serum aldolase isoenzyme patterns in the diagnosis of primary hepatocellular carcinoma.
Suppression of fructose-bisphosphate aldolase C expression as a predictor of advanced oral squamous cell carcinoma.
Use of serum gamma-enolase and aldolase A in combination as markers for renal cell carcinoma.
[Aldolase activity in carcinoma of the prostate.]
[Behavior of the enzymes, aldolase, lactate dehydrogenase and malate dehydrogenase in untreated carcinoma of the endometrium]
[Comparative characteristics of muscle aldolase in the norm, thyreotoxicosis and development of Brown-Pearch carcinoma in rabbits]
[Determination of aldolase A by radioimmunoassay. Experimental and clinical studies on the diagnosis of cancer of the digestive tract]
[DETERMINATION OF THE ALDOLASE LEVEL IN SERUM AS A DIAGNOSTIC METHOD IN PATIENTS WITH SUSPECTED CARCINOMA OF THE PROSTATE.]
[Diagnostic value of biochemical tumor markers in serum of patients with cancer of the ovary]
[On serum aldolase activity in carcinomas of the prostate]
[Serum aldolase activity in patients with laryngeal carcinoma]
[SERUM ALDOLASE ACTIVITY IN PATIENTS WITH UTERINE CARCINOMA UNDERGOING RADIOTHERAPY.]
[The value of enzyme determinations in the differential diagnosis of prostatic hypertrophy and carcinoma. Parallel evaluation of the behavior of acid phosphatases, aldolase, malic and lactic dehydrogenases.]
[Value of serum aldolase in the early diagnosis of prostatic carcinoma]
Carcinoma, Bronchogenic
Enzymatic tests in the prognosis and course controls in bronchial carcinoma patients.
[Increase in serum aldolase caused by bronchial carcinoma]
[Relevance of serum aldolase for the detection of liver metastases of bronchial cancer--comparative enzymatic and endoscopy-autopsy studies]
[The value determination of serum aldolase for findings of metastases and relapses on bronchial carcinoma (author's transl)]
Carcinoma, Ehrlich Tumor
[A preliminary study on the gene expression of aldolase isozymes and chromatin composition and transcription in Ehrlich ascites tumor and the host liver]
Carcinoma, Embryonal
Isoenzyme transitions of creatine phosphokinase, aldolase and phosphoglycerate mutase in differentiating mouse cells.
Carcinoma, Hepatocellular
A shift of liver aldolase towards the muscle type in hepatoma: immunological study.
Aberrant expression of the glycolytic enzymes aldolase B and type II hexokinase in hepatocellular carcinoma are predictive markers for advanced stage, early recurrence and poor prognosis.
Activity of the rat liver-specific aldolase B promoter is restrained by HNF3.
Aldolase A Enhances Intrahepatic Cholangiocarcinoma Proliferation and Invasion through Promoting Glycolysis.
Aldolase A isoenzyme levels in serum and tissues of patients with liver diseases.
Aldolase B inhibits metastasis through Ten-Eleven Translocation 1 and serves as a prognostic biomarker in hepatocellular carcinoma.
Aldolase isoenzymes in liver cirrhosis and primary liver cell cancer.
Alteration of aldolase isozymes in serum and tissues of patients with cancer and other diseases.
Binding of AlF-C, an Orc1-binding transcriptional regulator, enhances replicator activity of the rat aldolase B origin.
Cell localization of aldolase fetal isozymes in rat regenerating liver: differences with hepatoma.
Cell types involved in the expression of foetal aldolases during rat azo-dye hepatocarcinogenesis.
Characterization of messenger RNA for fructose 1,6-bisphosphate aldolase A isozyme of rat ascites hepatoma AH 7974 cells.
Competition between transcription factors HNF1 and HNF3, and alternative cell-specific activation by DBP and C/EBP contribute to the regulation of the liver-specific aldolase B promoter.
Different expression of rat aldolase A mRNA in the skeletal muscle and ascites hepatoma cells.
Effect of Plumbagin on some glucose metabolising enzymes studied in rats in experimental hepatoma.
Enhancement of the human factor IX expression, mediated by an intron derived fragment from the rat aldolase B gene in cultured hepatoma cells
Enhancement of the human factor IX expression, mediated by an intron derived fragment from the rat aldolase B gene in cultured hepatoma cells.
Expression of aldolase A messenger RNAs in human adult and foetal tissues and in hepatoma.
Fetal pattern of aldolase in transplantable hepatomas.
Fructose-1,6-Bisphosphate Aldolase B Depletion Promotes Hepatocellular Carcinogenesis Through Activating Insulin Receptor Signaling and Lipogenesis.
Fructose-Bisphosphate Aldolase A Regulates Hypoxic Adaptation in Hepatocellular Carcinoma and Involved with Tumor Malignancy.
Functional studies by site-directed mutagenesis on the role of Sp1 in the expression of the pyruvate kinase M and aldolase A genes.
Gene expression in clonally derived cell lines produced by in vitro transformation of rat fetal hepatocytes: isolation of cell lines which retain liver-specific markers.
Genes encoding Pir51, Beclin 1, RbAp48 and aldolase b are up or down-regulated in human primary hepatocellular carcinoma.
High expression of aldolase A is associated with tumor progression and poor prognosis in hepatocellular carcinoma.
Human aldolase B serum levels: a marker of liver injury.
Human aldolase C: characterization of the recombinant enzyme expressed in Escherichia coli.
Identification of four isoforms of aldolase B down-regulated in hepatocellular carcinoma tissues by means of two-dimensional Western blotting.
Illegitimate transcription: transcription of any gene in any cell type.
Inhibition of hypoxia-inducible factor 1 activity by nitric oxide donors in hypoxia.
Isozyme differentiation of aldolase and pyruvate kinase in fetal, regenerating, preneoplastic, and malignant rat hepatocytes during culture.
Modifications of the expression of liver-specific and non-specific messenger RNAs during azo-dye hepatocarcinogenesis.
Modulating effect of Semecarpus anacardium Linn. nut extract on glucose metabolizing enzymes in aflatoxin B1-induced experimental hepatocellular carcinoma.
Muscle type isoenzymes of liver aldolase in hepatomas.
Purification of aldolase C from rat brain and hepatoma.
Quantitative analysis of aldolase A mRNA in liver discriminates between hepatocellular carcinoma and cirrhosis.
Redox-regulated expression of glycolytic enzymes in resting and proliferating rat thymocytes.
Sequence requirement for replication initiation at the rat aldolase B locus implicated in its functional correlation with transcriptional regulation.
Starvation-induced lysosomal degradation of aldolase B requires glutamine 111 in a signal sequence for chaperone-mediated transport.
Studies on isoenzymes in relation to cancer. II: Serum aldolase isoenzyme patterns in the diagnosis of primary hepatocellular carcinoma.
Subunit-specific radioimmunoassay for aldolase A, B, and C subunits: clinical significance.
Synthesis in vitro of aldolase A by polysomes or mRNA of rat ascites hepatoma AH 7974 cells.
The antitumor role of a newly discovered ?-d-glucan from Holotrichia diomphalia Bates as a selective blocker of aldolase A.
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance.
The presence of aldolase C in rat hepatoma.
The structure of brain-specific rat aldolase C mRNA and the evolution of aldolase isozyme genes.
Tissue and serum aldolase of rats with primary hepatoma.
Tissue-specific expression of rat aldolase A mRNAs. Three molecular species differing only in the 5'-terminal sequences.
Two different aldolase A mRNA species in rat tissues.
Use of FDP and F1P aldolase to detect tumorous and nontumorous tissue damage by ethanol injection of hepatocellular carcinoma.
Use of fructose 1,6-diphosphate aldolase to detect tumour necrosis after transcatheter arterial embolization of hepatocellular carcinoma.
[Action of muscle-aldolase antiserum on aldolase of human hepatoma and of human fetal liver]
[Activities of several enzymes of glycolysis and of the glucose shunt in the Albert hepatoma of mouse (author's transl)]
[Biochemical and immunohistochemical studies on alteration of aldolase isozymes in rat liver in the process of hepatocarcinogenesis by administration of a diet containing 3'-methyl-4-dimethylaminoazobenzene]
[Change in aldolase activity in the organs of mice in the process of hepatoma 22a development]
[Determination of aldolase A by radioimmunoassay. Experimental and clinical studies on the diagnosis of cancer of the digestive tract]
[Experimental study on aldolase isozyme during the development of hepatoma in the rat (author's transl)]
[Fetal type of hepatic aldolase in a case of human hepatoma.]
[Fetal-type anomalies of the isoenzymes of aldolase and lactic dehydrogenase in ascitic hepatomas]
[Immunoreactivities and messenger RNA expression of aldolase A and B in human hepatoma cell lines]
[Inhibitory action of adenosine triphosphate on human hepatoma aldolase]
Carcinoma, Lewis Lung
Detachment of glycolytic enzymes from cytoskeleton of Lewis lung carcinoma and colon adenocarcinoma cells induced by clotrimazole and its correlation to cell viability and morphology.
Carcinoma, Medullary
Aldolase C in neuroendocrine tumors: an immunohistochemical study.
Carcinoma, Non-Small-Cell Lung
Aldolase A promotes proliferation and G1/S transition via the EGFR/MAPK pathway in non-small cell lung cancer.
Feedback regulation of ALDOA activates the HIF-1?/MMP9 axis to promote lung cancer progression.
Carcinoma, Renal Cell
A classification of tumor development based on an analysis of enzymes in tissue sections of hypernephroid carcinoma in man.
An immunochemical and immunohistochemical study of aldolase isozymes in renal cell carcinoma.
Elevated levels of serum aldolase A in patients with renal cell carcinoma.
Expression of aldolase C isozyme in renal cell carcinoma.
High expression of Aldolase A predicts poor survival in patients with clear-cell renal cell carcinoma.
High expression of fructose-bisphosphate aldolase A induces progression of renal cell carcinoma.
Histological examination of the aldolase monomer composition of cells from human kidney and hypernephroid carcinoma.
Use of serum gamma-enolase and aldolase A in combination as markers for renal cell carcinoma.
Carcinoma, Small Cell
Aldolase C in neuroendocrine tumors: an immunohistochemical study.
Carcinoma, Squamous Cell
Aldolase A promotes proliferation and G1/S transition via the EGFR/MAPK pathway in non-small cell lung cancer.
Aldolase C in neuroendocrine tumors: an immunohistochemical study.
Fructose-bisphosphate aldolase a is a potential metastasis-associated marker of lung squamous cell carcinoma and promotes lung cell tumorigenesis and migration.
Cardiomegaly
ALDOA protects cardiomyocytes against H/R-induced apoptosis and oxidative stress by regulating the VEGF/Notch 1/Jagged 1 pathway.
Aldolase promotes the development of cardiac hypertrophy by targeting AMPK signaling.
Regulation of membrane-mediated chronic muscle degeneration in dystrophic hamsters by calcium-channel blockers: diltiazem, nifedipine and verapamil.
Cardiomyopathies
Effect of fasting, phenobarbital, or hydrocortisone on serum creatine-phosphokinase and aldolase activity in myopathic Syrian hamsters.
Central Nervous System Diseases
[Activity of serum creatine kinase, aldolase and aminotransferases in central nervous system diseases]
Cerebral Hemorrhage
Serum aldolase isozyme levels in patients with cerebrovascular diseases.
Cerebral Infarction
Association of serum levels of antibodies against ALDOA and FH4 with transient ischemic attack and cerebral infarction.
Serum aldolase isozyme levels in patients with cerebrovascular diseases.
Cerebral Palsy
The present status of prenatal detection of neural tube defects.
Cerebrovascular Disorders
Serum aldolase isozyme levels in patients with cerebrovascular diseases.
Serum and cerebrospinal fluid creatine phosphokinase, aldolase and lactic dehydrogenase in cerebrovascular diseases.
Serum and cerebrospinal fluid enzymes in cerebrovascular disease. Creatine phosphokinase, aldolase, and lactic dehydrogenase.
[Aldolase and lactic dehydrogenase in the serum of patients with cerebrovascular diseases.]
Chagas Disease
Biochemical characterization of myocardial damage in chronic Chagas' disease.
Charcot-Marie-Tooth Disease
Investigations on enzyme activity in the serum and CSF of patients with neuromuscular diseases.
Chemical and Drug Induced Liver Injury
[Phosphatidylcholine-induced repair of damaged hepatocyte membranes in heliotrine poisoning]
[Protective effect of phosphatidylcholine liposomes in experimental toxic hepatitis]
Cholangiocarcinoma
Aldolase A Enhances Intrahepatic Cholangiocarcinoma Proliferation and Invasion through Promoting Glycolysis.
miR-122-5p Inhibits the Proliferation, Invasion and Growth of Bile Duct Carcinoma Cells by Targeting ALDOA.
Cholecystitis
[Use of transaminase and aldolase activity indices and the bile content of bilirubin and cholesterol for evaluating the activity of cholecystitis and hepatitis]
Cholecystitis, Acute
[On the clinical significance of the determination of aldolase and transaminase activity in acute cholecystitis and acute appendicitis]
[On the diagnostic role of aldolase and transaminase in complex liver function tests in patients with acute cholecystitis.]
Cholelithiasis
[Changes in the serum asparatand alanine transaminasae, phosphomonoesterase I and fructose 1-6 diphosphate aldolase in the preoperative and postoperative period of patients with cholelithiasis and cancer of the pancreas]
Cholestasis
Erythrocytic enzymes of phosphorylating glycolysis. The aldolase activity in full blood, erythrocytes and plasma in women with a normal course of gestation and with intrahepatic cholestasis of pregnancy.
[Enzymes phosphorylating glycolysis in erythrocytes. I. Aldolase activity in full blood, erythrocytes and plasma in women with normal course of gestation and pregnancy intrahepatic cholestasis]
Cholestasis, Intrahepatic
Erythrocytic enzymes of phosphorylating glycolysis. The aldolase activity in full blood, erythrocytes and plasma in women with a normal course of gestation and with intrahepatic cholestasis of pregnancy.
[Enzymes phosphorylating glycolysis in erythrocytes. I. Aldolase activity in full blood, erythrocytes and plasma in women with normal course of gestation and pregnancy intrahepatic cholestasis]
Coinfection
Co-reactivity of plasmodial histidine-rich protein 2 and aldolase on a combined immuno-chromographic-malaria dipstick (ICT) as a potential semi-quantitative marker of high Plasmodium falciparum parasitaemia.
[Experimental study of combined staphylococcal, streptococcal and adenovirus infections in tissue culture]
Colitis, Ulcerative
Real-time PCR quantification analysis of five mucosal transcripts in patients with Crohn's disease.
Colonic Neoplasms
Aldolase A overexpression is associated with poor prognosis and promotes tumor progression by the epithelial-mesenchymal transition in colon cancer.
Aldolase B impairs DNA mismatch repair and induces apoptosis in colon adenocarcinoma.
Aldolase B Overexpression is Associated with Poor Prognosis and Promotes Tumor Progression by Epithelial-Mesenchymal Transition in Colorectal Adenocarcinoma.
Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis.
Detachment of glycolytic enzymes from cytoskeleton of Lewis lung carcinoma and colon adenocarcinoma cells induced by clotrimazole and its correlation to cell viability and morphology.
MiR-122 Promotes the Development of Colon Cancer by Targeting ALDOA In Vitro.
The usability of a 15-gene hypoxia classifier as a universal hypoxia profile in various cancer cell types.
Colorectal Neoplasms
Aldolase B Overexpression is Associated with Poor Prognosis and Promotes Tumor Progression by Epithelial-Mesenchymal Transition in Colorectal Adenocarcinoma.
Aldolase triggers metabolic reprogramming in colorectal cancer in hypoxia and stiff desmoplastic microenvironments.
Effects of Hypoxia in Intestinal Tumors on Immune Cell Behavior in the Tumor Microenvironment.
Fructose-bisphosphate aldolase A is a key regulator of hypoxic adaptation in colorectal cancer cells and involved in treatment resistance and poor prognosis.
High expression of ALDOA and DDX5 are associated with poor prognosis in human colorectal cancer.
High expression of aldolase A is associated with tumor progression and poor prognosis in hepatocellular carcinoma.
Identification of aldolase A as a potential diagnostic biomarker for colorectal cancer based on proteomic analysis using formalin-fixed paraffin-embedded tissue.
Coma
Integration of PCR-Sequencing Analysis with Multiplex Ligation-Dependent Probe Amplification for Diagnosis of Hereditary Fructose Intolerance.
Molecular and clinical findings of Turkish patients with hereditary fructose intolerance.
Communicable Diseases
Cerebrospinal fluid fructose-biphosphate aldolase (aldolase) activity in infectious diseases of the central nervous system.
Connective Tissue Diseases
Eosinophilia-myalgia syndrome.
Contracture
Baseline Description of the Juvenile Localized Scleroderma Subgroup From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry.
[Nature of the changes in water-soluble enzyme activity in the action of injurious agents on the muscles. II. The change in the extractability of aldolase from muscles exposed to urea]
Cough
Eosinophilia-myalgia syndrome. Results of national surveillance.
Craniocerebral Trauma
Biochemical and biophysical changes in guinea pigs after acute head injury.
Creatine kinase BB and neuron-specific enolase in cerebrospinal fluid in the diagnosis of brain insult.
G6PC3, ALDOA and CS induction accompanies mir-122 down-regulation in the mechanical asphyxia and can serve as hypoxia biomarkers.
Modifications of plasma enzyme activities after severe head injury; evaluation of prognosis using multivariate methods.
Crohn Disease
Real-time PCR quantification analysis of five mucosal transcripts in patients with Crohn's disease.
Crush Syndrome
[Blood aldolase in the prolonged crush syndrome]
Cystadenoma
Proteomic analysis of pancreatic ductal adenocarcinoma compared with normal adjacent pancreatic tissue and pancreatic benign cystadenoma.
Cysts
Molecular Characterization of Aldolase from Heterodera glycines and Globodera rostochiensis.
Post-Transcriptional Gene Silencing Of The Gene Encoding Aldolase From Soybean Cyst Nematode By Transformed Soybean Roots.
Some glucose metabolic enzymes in various fractions of sarcocysts of Sarcocystis fusiformis of buffalo (Bubalus bubalis).
Univariate and classification analysis reveals potential diagnostic biomarkers for early stage ovarian cancer Type 1 and Type 2.
Deglutition Disorders
Scleromyxedema myopathy: case report and review of the literature.
Dehydration
A systems biology approach reveals major metabolic changes in the thermoacidophilic archaeon Sulfolobus solfataricus in response to the carbon source L-fucose versus D-glucose.
Engineering a Promiscuous Tautomerase into a More Efficient Aldolase for Self-Condensations of Linear Aliphatic Aldehydes.
Enhancement of the promiscuous aldolase and dehydration activities of 4-oxalocrotonate tautomerase by protein engineering.
New superfamily members identified for Schiff-base enzymes based on verification of catalytically essential residues.
Specific chemical modification of bacterial type I dehydroquinase--opportunities for drug discovery.
Dementia, Vascular
Codon 129 polymorphism specific cerebrospinal fluid proteome pattern in sporadic creutzfeldt-jakob disease and the implication of glycolytic enzymes in prion-induced pathology.
Dengue
Differential expression of aldolase, alpha tubulin and thioredoxin peroxidase in peripheral blood mononuclear cells from dengue fever and dengue hemorrhagic fever patients.
Dental Calculus
[ATP, phosphatases and aldolase in the supragingival dental calculus, dental deposit and salvia in parodontosis]
Dental Deposits
[ATP, phosphatases and aldolase in the supragingival dental calculus, dental deposit and salvia in parodontosis]
Dental Plaque
Identification, molecular cloning, and sequence analysis of a deoxyribose aldolase in Streptococcus mutans GS-5.
Dermatitis
Clinical characteristics and change in the antibody titres of patients with anti-MDA5 antibody-positive inflammatory myositis.
Dermatomyositis
A Case of Advanced Lung Adenocarcinoma with Nvolumab-associated Dermatomyositis.
Aldolase levels in dermatomyositis and polymyositis with normal creatine kinase levels.
Anti-MDA5 Antibody-positive Dermatomyositis Complicated by Autoimmune-associated Hemophagocytic Syndrome that was Successfully Treated with Immunosuppressive Therapy and Plasmapheresis.
Dermatomyositis with normal creatine kinase and elevated aldolase levels.
The utility of serum aldolase in normal creatine kinase dermatomyositis.
[A case report of a primary pure squamous cell carcinoma of the stomach associated with dermatomyositis (author's transl)]
[Dermatomyositis with squamous cell carcinoma of the lungs secondary to nivolumab treatment: a case report].
[Indices of transaminase and aldolase activity in dermatomyositis in children]
[SERUM ALDOLASE IN DERMATOMYOSITIS.]
Diabetes Complications
Sorbinil, an aldolase reductase inhibitor, in fighting against diabetic complications.
Diabetes Mellitus
[Diagnostic coefficients of ischemic heart disease in diabetes mellitus]
[General activity and isoenzymatic spectrum of aldolase in the evaluation of the course of diabetes mellitus]
[Total activity and isoenzyme spectrum of aldolase of erythrocytes in children with diabetes mellitus]
Diabetes Mellitus, Experimental
[Comparative study of the structural characteristics of aldolase in rabbit muscles in normal states and in alloxan diabetes]
Diabetes Mellitus, Type 1
Amelioration of type 1 diabetes by recombinant fructose-1,6-bisphosphate aldolase and cystatin derived from Schistosoma japonicum in a murine model.
Diabetes Mellitus, Type 2
Metabolism of [1,3-(13)C]glycerol-1,2,3-tris(methylsuccinate) and glycerol-1,2,3-tris(methyl[2,3-(13)C]succinate) in hepatocytes from Goto-Kakizaki rats.
Diabetic Neuropathies
[Therapeutic approach in peripheral neuropathies]
Digestive System Diseases
Serum aldolase in hepatobiliary disease.
Dirofilariasis
Fibrinolysis and proliferative endarteritis: two related processes in chronic infections? The model of the blood-borne pathogen Dirofilaria immitis.
Dysentery, Bacillary
[Aldolase activity in patients with mild forms of acute bacillary dysentery treated with chlortetracycline and bacteriophage.]
Dyskinesias
[A mitochondrial encephalomyopathy due to partial cytochrome c oxidase deficiency with giant evoked potentials--a case report]
Dyspnea
Association of the eosinophilia-myalgia syndrome with the ingestion of tryptophan.
Eosinophilia-myalgia syndrome. Results of national surveillance.
Eclampsia
[A study of transaminase and aldolase values in eclampsia]
[Transaminase, aldolase and lactic dehydrogenase activity of the human myometrium in pregnancy. Modifications of these activities in relation to the stage of pregnancy, the dynamics of uterine muscle and eclampsia.]
Encephalitis, Japanese
Inhibition of aldolase A blocks biogenesis of ATP and attenuates Japanese encephalitis virus production.
Encephalomyelitis, Venezuelan Equine
[Changes in the activity of aldolase and lactate dehydrogenase in cell culture fluid infected with a pathogenic and attenuated variant of Venezuelan equine encephalitis virus]
Endarteritis
Fibrinolysis and proliferative endarteritis: two related processes in chronic infections? The model of the blood-borne pathogen Dirofilaria immitis.
Endometrial Neoplasms
Aldolase mRNA expression in endometrial cancer and the role of clotrimazole in endometrial cancer cell viability and morphology.
Therapeutic potential of riboflavin, niacin and ascorbic Acid on carbohydrate metabolizing enzymes in secondary endometrial carcinoma bearing rats.
Eosinophilia
Common-source outbreak of trichinosis associated with eating raw home-butchered pork.
Eosinophilia-myalgia syndrome associated with L-tryptophan use.
Eosinophilia-myalgia syndrome.
Serum aldolase and lactate dehydrogenase levels in the eosinophilia myalgia syndrome.
The use of an elevated aldolase in diagnosing and managing eosinophilic fasciitis.
Tryptophan-induced eosinophilia-myalgia syndrome.
[Elevated serum aldolase activity in a patient of non-eosinophilic myofasciitis and synovitis with perifascicular atrophy]
Eosinophilia-Myalgia Syndrome
Serum aldolase and lactate dehydrogenase levels in the eosinophilia myalgia syndrome.
Erythema
A Case of Advanced Lung Adenocarcinoma with Nvolumab-associated Dermatomyositis.
Exanthema
A Case of Advanced Lung Adenocarcinoma with Nvolumab-associated Dermatomyositis.
Association of the eosinophilia-myalgia syndrome with the ingestion of tryptophan.
Eosinophilia-myalgia syndrome. Results of national surveillance.
Hemophagocytic Syndrome Complicated with Dermatomyositis Controlled Successfully with Infliximab and Conventional Therapies.
[Coxsackie virus infection. Associated with myositis and polyarthritis]
Fanconi Syndrome
Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice.
Fasciitis
Magnetic resonance imaging and serum aldolase concentration in eosinophilic fasciitis.
Myalgia in Patients with Dermatomyositis and Polymyositis Is Attributable to Fasciitis Rather Than Myositis: A Retrospective Study of 32 Patients who Underwent Histopathological Examinations.
Serum aldolase level is a useful indicator of disease activity in eosinophilic fasciitis.
The use of an elevated aldolase in diagnosing and managing eosinophilic fasciitis.
Fatty Liver
Chronic systemic exposure to IL6 leads to deregulation of glycolysis and fat accumulation in the zebrafish liver.
Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice.
Non-alcoholic fatty liver in hereditary fructose intolerance.
Foodborne Diseases
[Bilirubin, aldolase, lipoprotein and protein variations in human blood in acute food poisoning caused by staphylococci.]
fructokinase deficiency
Inborn errors of fructose metabolism.
Fructose Intolerance
A new aldolase B variant, N334K, is a common cause of hereditary fructose intolerance in Yugoslavia.
A newly identified aldolase B splicing mutation (G-->C, 5' intron 5) in hereditary fructose intolerance from New Zealand.
A Novel Frameshift Mutation of the ALDOB Gene in a Korean Girl Presenting with Recurrent Hepatitis Diagnosed as Hereditary Fructose Intolerance.
A partially active mutant aldolase B from a patient with hereditary fructose intolerance.
A radioisotopic method for fructose-1-phosphate aldolase assay that facilitates diagnosis of hereditary fructose intolerance.
A structurally modified liver aldolase in fructose intolerance: immunological and kinetic evidence.
Absence of renal fructose-1-phosphate aldolase activity in hereditary fructose intolerance.
Acute liver failure in neonates with undiagnosed hereditary fructose intolerance due to exposure from widely available infant formulas.
Adult hereditary fructose intolerance.
Aldolase activities of the small intestinal mucosa in malabsorption states and hereditary fructose intolerance.
Aldolase B A149P mutation and hereditary fructose intolerance are not associated with sudden infant death syndrome.
Aldolase B and fructose intolerance.
Aldolase B mutations and prevalence of hereditary fructose intolerance in a Polish population.
Aldolase B mutations in Italian families affected by hereditary fructose intolerance.
Aldolase-B knockout in mice phenocopies hereditary fructose intolerance in humans.
Allelic heterogeneity in adult hereditary fructose intolerance. Detection of structural mutations in the aldolase B molecule.
Alteration of substrate specificity by a naturally-occurring aldolase B mutation (Ala337-->Val) in fructose intolerance.
Antibody activation of mutant human fructosediphosphate aldolase B in liver extracts of patients with hereditary fructose intolerance.
Association of the widespread A149P hereditary fructose intolerance mutation with newly identified sequence polymorphisms in the aldolase B gene.
Case report: heterogeneity of aldolase B in hereditary fructose intolerance.
Catalytic deficiency of human aldolase B in hereditary fructose intolerance caused by a common missense mutation.
Characterization of recombinant human aldolase B and purification by metal chelate chromatography.
Clinical and genetic analysis for a Chinese family with hereditary fructose intolerance.
Daily Fructose Traces Intake and Liver Injury in Children with Hereditary Fructose Intolerance.
Determination of fructose metabolic pathways in normal and fructose-intolerant children: a 13C NMR study using [U-13C]fructose.
Different genotypes in a large Italian family with recurrent hereditary fructose intolerance.
Diverse mutations in the aldolase B gene that underlie the prevalence of hereditary fructose intolerance.
DNA analysis in patients with hereditary fructose intolerance.
DNA diagnosis of fatal fructose intolerance from archival tissue.
Epidemiological aspects of hereditary fructose intolerance: a database study.
Expression, purification, and characterization of natural mutants of human aldolase B. Role of quaternary structure in catalysis.
Fructose intolerance with normal liver aldolase.
Fructose-1-phosphate aldolase and fructose-1-6-diphosphate aldolase activity in the mucosa of the intestine in hereditary fructose intolerance.
Fructose-1-phosphate and fructose-1,6-bisphosphate aldolases in the small intestinal mucosa.
Fructosuria and recurrent hypoglycemia in a patient with a novel c.1693T>A variant in the 3' untranslated region of the aldolase B gene.
Functional and molecular modelling studies of two hereditary fructose intolerance-causing mutations at arginine 303 in human liver aldolase.
Hereditary fructose intolerance caused by a nonsense mutation of the aldolase B gene.
Hereditary Fructose Intolerance Diagnosed in Adulthood.
Hereditary fructose intolerance presenting as Reye's-like syndrome: report of one case.
Hereditary fructose intolerance, an inborn deficiency of liver aldolase complex.
Hereditary fructose intolerance.
Hereditary fructose intolerance. An inborn defect of hepatic fructose-1-phosphate splitting aldolase.
Hereditary fructose intolerance: frequency and spectrum mutations of the aldolase B gene in a large patients cohort from France--identification of eight new mutations.
Hereditary fructose intolerance: functional study of two novel ALDOB natural variants, and characterization of a partial gene deletion.
Identification of a novel mutation (Leu 256-->Pro) in the human aldolase B gene associated with hereditary fructose intolerance.
Identification of a novel mutation (Leu256-->Pro) in the human aldolase B gene associated with hereditary fructose intolerance.
Identification of a splice-site mutation in the aldolase B gene from an individual with hereditary fructose intolerance.
Inborn errors of fructose metabolism.
Increased prevalence of mutant null alleles that cause hereditary fructose intolerance in the American population.
Integration of PCR-Sequencing Analysis with Multiplex Ligation-Dependent Probe Amplification for Diagnosis of Hereditary Fructose Intolerance.
Interaction between aldolase and vacuolar H+-ATPase: evidence for direct coupling of glycolysis to the ATP-hydrolyzing proton pump.
Isoelectrofocusing of aldolase B from normal human livers and from livers with hereditary fructose intolerance.
Isolation and characterization of a mutant liver aldolase in adult hereditary fructose intolerance. Identification of the enzyme variant by radioassay in tissue biopsy specimens.
Kinetic and immunological abnormalities of aldolase B in herediatry fructose intolerance.
Molecular analysis of aldolase B genes in hereditary fructose intolerance.
Molecular analysis of aldolase B genes in the diagnosis of hereditary fructose intolerance in the United Kingdom.
Molecular analysis of common aldolase B alleles for hereditary fructose intolerance in North Americans.
Molecular analysis of the aldolase B gene in patients with hereditary fructose intolerance from Spain.
Molecular and clinical findings of Turkish patients with hereditary fructose intolerance.
Molecular basis of hereditary fructose intolerance in Italy: identification of two novel mutations in the aldolase B gene.
Molecular basis of hereditary fructose intolerance: mutations and polymorphisms in the human aldolase B gene.
Molecular evidence for compound heterozygosity in hereditary fructose intolerance.
Molecular studies of liver aldolase B in hereditary fructose intolerance using blotting and immunological techniques.
Mutation analysis in Turkish patients with hereditary fructose intolerance.
Mutation of aldolase B genes in hereditary fructose intolerance.
Mutations in the promoter region of the aldolase B gene that cause hereditary fructose intolerance.
Neonatal screening for hereditary fructose intolerance: frequency of the most common mutant aldolase B allele (A149P) in the British population.
Neutrotoxic effects of fructose administration in rat brain: implications for fructosemia.
Novel six-nucleotide deletion in the hepatic fructose-1,6-bisphosphate aldolase gene in a patient with hereditary fructose intolerance and enzyme structure-function implications.
Null alleles of the aldolase B gene in patients with hereditary fructose intolerance.
Partial aldolase B gene deletions in hereditary fructose intolerance.
Patients With Aldolase B Deficiency Are Characterized by Increased Intrahepatic Triglyceride Content.
Patients with hereditary fructose intolerance have normal erythrocyte aldolase activity.
Pitfalls in the Diagnosis of Hereditary Fructose Intolerance.
Possible role of thiol groups in the abnormal kinetics of aldolase in hereditary fructose intolerance.
Recent advances in the pathogenesis of hereditary fructose intolerance: implications for its treatment and the understanding of fructose-induced non-alcoholic fatty liver disease.
Semi-automated, reverse-hybridization detection of multiple mutations causing hereditary fructose intolerance.
Serum aldolase in Tay-Sachs disease and in fructose intolerance.
Simple method for detection of mutations causing hereditary fructose intolerance.
Six novel alleles identified in Italian hereditary fructose intolerance patients enlarge the mutation spectrum of the aldolase B gene.
Snapshots of catalysis: the structure of fructose-1,6-(bis)phosphate aldolase covalently bound to the substrate dihydroxyacetone phosphate.
Social and health care needs in patients with hereditary fructose intolerance in Spain.
Stabilization of the predominant disease-causing aldolase variant (A149P) with zwitterionic osmolytes.
Structural and functional analysis of aldolase B mutants related to hereditary fructose intolerance.
Structural mutation of aldolase B in hereditary fructose intolerance: electrofocusing results.
Structure of the thermolabile mutant aldolase B, A149P: molecular basis of hereditary fructose intolerance.
Studies with type I aldolase to understand fructose intolerance and combat parasitic disease.
The biochemical basis of hereditary fructose intolerance.
The histochemical demonstration of fructose-1-phosphate aldolase and fructose-1-6-diphosphate aldolase, and application of the method to a case of fructose intolerance.
The molecular basis of hereditary fructose intolerance in Italian children.
The spectrum of aldolase B (ALDOB) mutations and the prevalence of hereditary fructose intolerance in Central Europe.
The structure of human liver fructose-1,6-bisphosphate aldolase.
The temperature dependence of activity and structure for the most prevalent mutant aldolase B associated with hereditary fructose intolerance.
Transferrin hypoglycosylation in hereditary fructose intolerance: using the clues and avoiding the pitfalls.
Transferrin Isoforms, Old but New Biomarkers in Hereditary Fructose Intolerance.
When Long-Lasting Food Selectivity Leads to an Unusual Genetic Diagnosis: A Case Report.
[Adults with hereditary fructose intolerance: risks of fructose infusion]
[Clinical heterogeneity in fructose intolerance]
[Congenital fructose intolerance. New molecular aspects]
[Hepatic aldolase in fructose intolerance]
[Hereditary fructose intolerance]
[Liver fructose-1-phosphate and fructose-1,6-diphosphate aldolase deficiency in hereditary fructose intolerance (author's transl)]
[Study of hereditary fructose intolerance by methods of molecular biology]
[The biochemical lesion of fructose intolerance. Immunologic detection of a modified aldolase]
fructose-bisphosphate aldolase deficiency
A syndrome of mental retardation, short stature, hemolytic anemia, delayed puberty, and abnormal facial appearance: similarities to a report of aldolase A deficiency.
A thermolabile aldolase A mutant causes fever-induced recurrent rhabdomyolysis without hemolytic anemia.
Acute rhabdomyolysis and inflammation.
Aldolase A deficiency: Report of new cases and literature review.
Aldolase B mutations in Italian families affected by hereditary fructose intolerance.
Alteration of substrate specificity by a naturally-occurring aldolase B mutation (Ala337-->Val) in fructose intolerance.
Epidemiological aspects of hereditary fructose intolerance: a database study.
FRUCTOSE-1 PHOSPHATE ALDOLASE DEFICIENCY IN TAY-SACHS DISEASE.
Glycogen storage disease type XII; an ultra rare cause of hemolytic anemia and rhabdomyolysis: one new case report.
Glycogen storage myopathies.
Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr).
Hereditary fructose intolerance caused by a nonsense mutation of the aldolase B gene.
Hereditary fructose intolerance.
Human aldolase A deficiency associated with a hemolytic anemia: thermolabile aldolase due to a single base mutation.
Human aldolase A of a hemolytic anemia patient with Asp-128----Gly substitution: characteristics of an enzyme generated in E. coli transfected with the expression plasmid pHAAD128G.
Inborn errors of fructose metabolism.
Molecular studies of liver aldolase B in hereditary fructose intolerance using blotting and immunological techniques.
Patients With Aldolase B Deficiency Are Characterized by Increased Intrahepatic Triglyceride Content.
Red cell aldolase deficiency and hemolytic anemia: a new syndrome.
Red cell aldolase deficiency in hereditary spherocytosis.
Red cell enzymopathies as a model of inborn errors of metabolism.
Severe acidosis in a neonate with pulmonary valve stenosis: a possible stress inducer of a fatal syndrome of fructose-1, 6-biphosphatase and aldolase deficiency.
Social and health care needs in patients with hereditary fructose intolerance in Spain.
Stabilization of the predominant disease-causing aldolase variant (A149P) with zwitterionic osmolytes.
Tarui disease and distal glycogenoses: clinical and genetic update.
Two cases of red cell aldolase deficiency associated with hereditary hemolytic anemia in a Japanese family.
[Aldolase A deficiency]
[Aldolase deficiency]
[Anesthesia for a patient with red cell aldolase deficiency]
[Contribution to the study of the mechanism of hypoglycemia in fructoaldolase deficiency. Preliminary note]
[Liver fructose-1-phosphate and fructose-1,6-diphosphate aldolase deficiency in hereditary fructose intolerance (author's transl)]
Genetic Diseases, Inborn
Daily Fructose Traces Intake and Liver Injury in Children with Hereditary Fructose Intolerance.
Giardiasis
Biochemical quantification of crypt hyperplastic villous atrophy by aldolase activity assay.
Glioblastoma
Aldolase C in cultured mouse glioblastoma cells.
Biomarker discovery: a proteomic approach for brain cancer profiling.
Enrichment of Aldolase C Correlates with Low Non-Mutated IDH1 Expression and Predicts a Favorable Prognosis in Glioblastomas.
Glioma
A novel lncRNA ARST represses glioma progression by inhibiting ALDOA-mediated actin cytoskeleton integrity.
Aldolase C in cultrued rat glioma.
An Adult Drosophila Glioma Model for Studying Pathometabolic Pathways of Gliomagenesis.
Glycolytic enzymes from human neuroectodermal tumors of childhood.
Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis.
Phosphorylation of pyruvate kinase and glycolytic metabolism in three human glioma cell lines.
Glomerulonephritis
Aldolase and adenosine deaminase activity in lymphocytes of patients with glomerulonephritis.
glyceraldehyde-3-phosphate dehydrogenase (nad(p)+) (phosphorylating) deficiency
A simple screening procedure for glucose phosphate isomerase, phosphofructokinase, aldolase and glyceraldehyde-3-phosphate dehydrogenase deficiencies.
Glycogen Storage Disease
Glycogen storage disease type XII; an ultra rare cause of hemolytic anemia and rhabdomyolysis: one new case report.
Tarui disease and distal glycogenoses: clinical and genetic update.
[Determination of blood level of muscle enzymes in glycogenoses with liver involvement: a diagnostic criterion]
Goiter
[Studies on the thyroid gland. II. Phosphatase and aldolase activity in surgical material from goiter changed human thyroid glands]
Granuloma
Protective effect and granuloma down-modulation promoted by RP44 antigen a fructose 1,6 bisphosphate aldolase of Schistosoma mansoni.
Heart Defects, Congenital
[Behavior of lactate-dehydrogenase isoenzymes (LDH), aspartate-aminotransferase (GOT) and aldolase in the blood plasma of children with congenital heart defects]
Heart Diseases
Serum aldolase activity inacute heart disease.
Heart Failure
ALDOA protects cardiomyocytes against H/R-induced apoptosis and oxidative stress by regulating the VEGF/Notch 1/Jagged 1 pathway.
Biochemical characterization of myocardial damage in chronic Chagas' disease.
[Serum aldolase activity in chronic heart failure.]
Hemorrhagic Fevers, Viral
Fatal malaria infection in travelers: novel immunohistochemical assays for the detection of Plasmodium falciparum in tissues and implications for pathogenesis.
Hepatic Insufficiency
[THE ROLE OF HEPATIC INSUFFICIENCY IN INFANTILE BRONCHIAL ASTHMA. II. THE SERUM LEVELS OF ALDOLASE. PRELIMINARY NOTE.]
Hepatitis
A Novel Frameshift Mutation of the ALDOB Gene in a Korean Girl Presenting with Recurrent Hepatitis Diagnosed as Hereditary Fructose Intolerance.
ALDOB acts as a novel HBsAg-binding protein and its coexistence inhibits cisplatin-induced HepG2 cell apoptosis.
Aldolase test on guinea pigs infected with blood of patients affected with hepatitis epidemica.
Comparative investigations of the behaviour of the aldolase test, urobilinogenuria test and the colloid oscillation test on the blood serum of persons from the environment of patients affected with hepatitis epidemica.
Comparative investigations on hepatic and muscular serum aldolase in epidemic hepatitis.
Detection of autoantibody to aldolase B in sera from patients with troglitazone-induced liver dysfunction.
Examination of the aldolase activity in tissue cultures infected with material from patients suffering with hepatitis epidemica.
Human aldolase B subunit-specific radioimmunoassay.
Investigations on applying the aldolase test in the epidemiology of hepatitis epidemica.
Investigations on the correlation between aldolase reaction, urobilinogenuria and colloid oscillation test on the blood serum of persons from the environment of patients suffering from hepatitis epidemica.
Serum aldolase activity in preicteric stage of acute hepatitis.
Studies on some serum enzyme levels in various liver diseases.
Subunit-specific radioimmunoassay for aldolase A, B, and C subunits: clinical significance.
[A case of fulminant psittacosis showing Chlamydia in TBLB specimens]
[Activity of aldolase isoenzymes in viral hepatitis]
[Activity of aldolase, phosphohexioisomerase, and alkaline phosphatase in saliva and blood of patients with epidemic hepatitis]
[Activity of aldolase, pseudocholinesterase and transaminases in the blood serum in epidemic hepatitis.]
[Aldolase isoenzymatic spectrum in acute liver necrosis in relation to viral hepatitis]
[Aldolase reaction to fructose-1,6-phosphate and fructose-1-phosphate in patients with trichinosis and viral hepatitis]
[Aldolase]
[Biological importance of transaminases and aldolase. Their value in the clinical picture of acute viral hepatitis.]
[Blood aldolase determination as diagnostic test in epidemic hepatitis.]
[Characteristics of the molecular diversities of human and rat aldolase via starch and agar gel electrophoresis]
[Comparative and dynamic studies of the value of the serum transaminase and aldolase and the methylene blue tests in diagnosis of human epidemic hepatitis.]
[Determination of transaminase and aldolase activity for early diagnosis of epidemic hepatitis (Botkin's disease)]
[DIAGNOSTIC SIGNIFICANCE OF THE ALDOLASE TEST IN EPIDEMIC HEPATITIS.]
[Effect of corticoids on serum aldolase activity in the course of viral hepatitis]
[EFFECT OF NOVOCAIN BLOCK ON THE CONTENT OF PROCONVERTIN IN THE BLOOD PLASMA AND ON THE ACTIVITY OF ALDOLASE IN THE BLOOD SERUM IN EPIDEMIC HEPATITIS PATIENTS.]
[Immunochemical studies on aldolase isoenzymes in human serum (author's transl)]
[Mechanism of increased serum aldolase in epidemic hepatitis (Botkin's disease).]
[On the diagnostic and prognostic significance of aldolase activity in epidemic hepatitis in children.]
[ON THE DIAGNOSTIC SIGNIFICANCE OF THE DETERMINATION OF ALDOLASE ACTIVITY IN THE BLOOD OF PATIENTS WITH EPIDEMIC HEPATITIS.]
[On the diagnostic value of the activity of aldolase in epidemic hepatitis in children.]
[On the value of lactate dehydrogenase and aldolase determination as a hepatitis screening test in blood donors]
[Our experiences with determination of serum aldolase activity in the diagnosis of viral infective hepatitis]
[Potential serum aldolase activity, a new characteristic of epidemic hepatitis]
[Relation of serum aldolase activity to histological changes in the liver in acute hepatitis and other liver disorders.]
[Relations between the indices of aldolase and transaminases in the blood and urine of children with epidemic hepatitis]
[Serum aldolase isoenzymes in patients with hepatitis]
[Serum aldolase isoenzymes: differential distribution pattern in virus hepatitis B and virus hepatitis non-B]
[Study of the dynamics of serum aldolase activity in patients of epidemic hepatitis.]
[Transaminase and aldolase in the diagnosis of epidemic hepatitis.]
[Use of transaminase and aldolase activity indices and the bile content of bilirubin and cholesterol for evaluating the activity of cholecystitis and hepatitis]
[Value of determining the urinary aldolase and transaminase activity in evaluating the completeness of recovery from viral hepatitis]
[Value of serum aldolase determination for control of the parenchymal sequels of epidemic hepatitis.]
Hepatitis A
Serum aldolase isoenzymes in athletes at rest and after long-lasting exercise.
[Aldolase reaction in infectious hepatitis.]
[Behavior of glutamic-acetic and racemic acid transaminase and aldolase during the course of infectious hepatitis.]
[Clinical value of aldolase reaction in comparison with other liver function tests in infectious hepatitis.]
[The diagnostic value of determining serum fructose-1-phosphate aldolase and alanine aminotransferase activity in patients with infectious hepatitis in the foci]
Hepatitis B
ALDOB acts as a novel HBsAg-binding protein and its coexistence inhibits cisplatin-induced HepG2 cell apoptosis.
Autoantibody to aldolase in acute and chronic hepatitis.
[Serum aldolase isoenzymes: differential distribution pattern in virus hepatitis B and virus hepatitis non-B]
Hepatitis C
Identification of four isoforms of aldolase B down-regulated in hepatocellular carcinoma tissues by means of two-dimensional Western blotting.
Hepatitis C, Chronic
Quantitative analysis of aldolase A mRNA in liver discriminates between hepatocellular carcinoma and cirrhosis.
Hepatitis, Alcoholic
Studies on some serum enzyme levels in various liver diseases.
Hepatitis, Chronic
Autoantibody to aldolase in acute and chronic hepatitis.
Detection of autoantibody to aldolase B in sera from patients with troglitazone-induced liver dysfunction.
Human aldolase B serum levels: a marker of liver injury.
Studies on some serum enzyme levels in various liver diseases.
[Aldolase isoenzymes in infectious (Botkin's disease) and chronic hepatitis]
[Aldolase]
[Significance of isoenzymes in acute hepatitis and differential diagnosis of chronic forms of hepatitis]
Herpes Simplex
[Specific features of a change in some blood biochemical indicators in virus urogenital infections].
Herpesviridae Infections
[Aminotransferase and aldolase activity in herpesvirus infections]
Hodgkin Disease
[Blood serum aldolase level in children with lymphoblastic leukemia and Hodgkin's disease]
Hypergammaglobulinemia
Baseline characteristics and long-term outcomes of eosinophilic fasciitis in 89 patients seen at a single center over 20 years.
Dermatomyositis with panniculitis.
The use of an elevated aldolase in diagnosing and managing eosinophilic fasciitis.
Hyperglycemia
TRThe Expression of Aldolase B in Islets is Negatively Associated with Insulin Secretion in Humans.
Hyperoxaluria
Calciuria, oxaluria and phosphaturia after ingestion of glucose, xylitol and sorbitol in two population groups with different stone-risk profiles.
Hypersensitivity
Fast-muscle-specific expression of human aldolase A transgenes.
Serum IgE cross-reactivity between fish and chicken meats in dogs.
Hypertension
Statin-induced delayed rhabdomyolysis.
[Activity of aldolase in the blood serum and erythrocytes in patients with hypertension and arteriosclerosis]
Hyperthyroidism
[Behavior of the activity of lactic acid dehydrogenase and aldolase in erythrocytes in experimental hyperthyroidism.]
[Intraerythrocytic enzyme activities in euthyroid subjects and hyperthyroid patients before treatment and following stabilization of metabolism using radioiodine therapy]
Hypoglycemia
Effect of gamma-hexachlorocyclohexane (lindane) on carp (Cyprinus carpio). II. Effects of chronic intoxication on blood, liver enzymes, and muscle plasmic membrane.
Fructosuria and recurrent hypoglycemia in a patient with a novel c.1693T>A variant in the 3' untranslated region of the aldolase B gene.
Integration of PCR-Sequencing Analysis with Multiplex Ligation-Dependent Probe Amplification for Diagnosis of Hereditary Fructose Intolerance.
Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice.
Molecular and clinical findings of Turkish patients with hereditary fructose intolerance.
[Contribution to the study of the mechanism of hypoglycemia in fructoaldolase deficiency. Preliminary note]
Hypogonadism
Decrease of aldolase and pyruvate kinase activity in erythrocytes of individuals with male hypogonadism as an expression of lack of androgen influence on the bone marrow.
Hyponatremia
Effect of gamma-hexachlorocyclohexane (lindane) on carp (Cyprinus carpio). II. Effects of chronic intoxication on blood, liver enzymes, and muscle plasmic membrane.
Hypothyroidism
Statin-induced delayed rhabdomyolysis.
[Hypothyroid myopathy in a young adult]
Infections
A diet-specific microbiota drives Salmonella Typhimurium to adapt its in vivo response to plant-derived substrates.
CHANGES IN ALDOLASE ACTIVITY FOLLOWING INFECTION WITH CERTAIN VIRUSES.
Changes in the intestinal enzyme activity of lambs during chronic infection with Trichostrongylus vitrinus.
Chlamydia pneumoniae effector chlamydial outer protein N sequesters fructose bisphosphate aldolase A, providing a benefit to bacterial growth.
Clearance dynamics of lactate dehydrogenase and aldolase following antimalarial treatment for Plasmodium falciparum infection.
Co-reactivity of plasmodial histidine-rich protein 2 and aldolase on a combined immuno-chromographic-malaria dipstick (ICT) as a potential semi-quantitative marker of high Plasmodium falciparum parasitaemia.
Cochliobolus lunatus down-regulates proteome at late stage of colonization and transiently alters StNPR1 expression in Solanum tuberosum L.
Comparative proteomic analysis of hepatic mechanisms of Megalobrama amblycephala infected by Aeromonas hydrophila.
Current progress in proteomic study of hepatitis C virus-related human hepatocellular carcinoma.
Differential expression of aldolase, alpha tubulin and thioredoxin peroxidase in peripheral blood mononuclear cells from dengue fever and dengue hemorrhagic fever patients.
Effect of trypanosomes infection on blood ascorbic acid and serum aldolase levels on the fresh water fishes, Clarias batrachus and Heteropneustus fossilis.
Evaluation of recombinant SjLAP and SjFBPA in detecting antibodies to Schistosoma japonicum.
Evaluation of the NOW Malaria Immunochromatographic Test for Quantitative Diagnosis of Falciparum and Vivax Malaria Parasite Density.
Evolutionary and functional analysis of fructose bisphosphate aldolase of plant parasitic nematodes.
Experimental paratuberculosis (Johne's disease)--studies on biochemical parameters in cattle.
Genotyping of Russian isolates of fungal pathogen Trichophyton rubrum, based on simple sequence repeat and single nucleotide polymorphism.
Host and Bacterial Glycolysis During Chlamydia trachomatis Infection.
Inhibition by stabilization: targeting the Plasmodium falciparum aldolase-TRAP complex.
Inhibition of aldolase A blocks biogenesis of ATP and attenuates Japanese encephalitis virus production.
Molecular approach for detecting early prepatent Schistosoma mansoni infection in Biomphalaria alexandrina snail host.
Molecular identification of Wolbachia and Sodalis glossinidius in the midgut of Glossina fuscipes quanzensis from the Democratic Republic of Congo.
Protective and anti-pathology effects of Sm fructose-1,6-bisphosphate aldolase-based DNA vaccine against schistosoma mansoni by changing route of injection.
Proteomic analysis reveals differentially abundant proteins probably involved in the virulence of amastigote and promastigote forms of Leishmania infantum.
Residual serologic reactivity in children with resolved Lyme arthritis.
Sequential changes in tissue D-fructose-1,6-diphosphate aldolase activity in chickens experimentally infected with Borrelia anserina.
Synthetic conjugate peptide Fba-Met6 (MP12) induces complement-mediated resistance against disseminated Candida albicans.
The hepatocyte-specific phenotype of murine liver cells correlates with high expression of connexin32 and connexin26 but very low expression of connexin43.
Three Prochlorococcus cyanophage genomes: signature features and ecological interpretations.
Tracing of Afferent Connections in the Zebrafish Cerebellum Using Recombinant Rabies Virus.
Tsutsugamushi infection-associated acute rhabdomyolysis and acute renal failure.
Unravelling the contribution of the Penicillium expansum PeSte12 transcription factor to virulence during apple fruit infection.
[Biochemical changes in the blood of geese infected with Borrelia anserina]
[Biochemical study of serum from sheep infected with Brucella ovis]
[Biological and parasitic variations in horses infested and reinfested by Trichinella spiralis]
[Effect of an experimental infestation with Cysticercus ovis on serum enzyme activity in lambs]
[Effect of nitroammofoska on the aldolase activity of the normal hemolymph in the mollusk Planorbarius banaticus and in trematode invasion]
[Glycolysis and pentose-phosphate pathway ratio in staphylococcus from the female genitalia in norm and dysbiosis]
[Metabolic aspects of hepatic tissue in infection of the mouse from EDP virus. I. Phosphoglucomutase, aldolase and enolase activity.]
Influenza, Human
Improved data visualization techniques for analyzing macromolecule structural changes.
Insulin Resistance
Effect of a high fructose diet on metabolic parameters in carriers for hereditary fructose intolerance.
Intellectual Disability
A syndrome of mental retardation, short stature, hemolytic anemia, delayed puberty, and abnormal facial appearance: similarities to a report of aldolase A deficiency.
Intestinal Obstruction
The relationship between the level of thirteen different substances and enzymes in blood and peritoneal fluid and the duration of mechanical intestinal obstruction: an experimental study on rats.
Intestinal Volvulus
Onchocerca volvulus glycolytic enzyme fructose-1,6-bisphosphate aldolase as a target for a protective immune response in humans.
Ischemic Attack, Transient
Association of serum levels of antibodies against ALDOA and FH4 with transient ischemic attack and cerebral infarction.
Joint Diseases
Serum samples of patients with rheumatoid arthritis contain a specific autoantibody to "denatured" aldolase A in the osteoblast-like cell line, MG-63.
[STUDY OF GLUTAMIC-OXALOACETIC TRANSAMINASE, GLUTAMIC-PYRUVIC TRANSAMINASE AND ALDOLASE IN THE SYNOVIA OF PATIENTS WITH POST-TRAUMATIC ARTHROPATHY.]
Kidney Diseases
[Behavior of blood aldolase in patients with kidney disease.]
Kidney Neoplasms
[Differential expression of genes that encode glycolysis enzymes in kidney and lung cancer in humans].
Leiomyoma
Activity of glycolytic enzymes and glucose-6-phosphate dehydrogenase in smooth muscle proliferation.
Compensatory alterations in energy homeostasis characterized in uterine tumors from hereditary leiomyomatosis and renal cell cancer.
Leiomyosarcoma
Activity of glycolytic enzymes and glucose-6-phosphate dehydrogenase in smooth muscle proliferation.
Leishmaniasis
Structures of type 2 peroxisomal targeting signals in two trypanosomatid aldolases.
Leprosy
Biochemical, immunological and genetic studies in leprosy. I. Changes in serum lactate dehydrogenase isoenzymes, creatine phosphokinase and aldolase activity in different forms of leprosy.
Muscle involvement in leprosy and its correlation with serum aldolase activity.
Leprosy, Lepromatous
Biochemical aspects of reactional states in leprosy.
Leprosy, Tuberculoid
Biochemical, immunological and genetic studies in leprosy. I. Changes in serum lactate dehydrogenase isoenzymes, creatine phosphokinase and aldolase activity in different forms of leprosy.
Leptospirosis
[Aldolase and transaminase activity in leptospirosis]
Leukemia
Localization of the gene responsible for the op (osteopetrotic) defect in rats on chromosome 10.
Promoter Mutation Analysis of ALDOA Gene in Solid Tumors and Acute Leukemias.
Studies on glycolytic enzymes in relation to cancer. I. Serum phosphohexose isomerase and aldolase in leukemia.
Studies on lactic dehydrogenase, lactic dehydrogenase isoenzymes and aldolase in human leukemias and on mechanism of those enzyme elevation.
Studies on the behavior of serum enzymes in human leukemia. I. Levels of aldolase, lactic dehydrogenase, glutamic oxalacetic transaminase and glutamic pyruvic transaminase with particular reference to clinical status.
[Clinical and experimental studies on aldolase and its isoenzymes in leukemia and allied hematological disorders (author's transl)]
[Clinical significance of aldolase A in sera of patients with leukemia]
[Clinical studies on aldolase and its isoenzymes in leukemia]
[Immunoreactivities and messenger RNA expression of aldolase A and B in human hepatoma cell lines]
[Prognostic significance of determining aldolase and lactate dehydrogenase activity of the cerebrospinal fluid in acute leukemia in children]
Leukemia, Lymphocytic, Chronic, B-Cell
Intracellular and serum levels of aldolase activity in B chronic lymphocytic leukemia.
Leukemia, Lymphoid
Intracellular and serum levels of aldolase activity in B chronic lymphocytic leukemia.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
[The cytological and biochemical aspects of studying the cerebrospinal fluid in patients with chronic myeloleukemia]
Leukocytosis
Tryptophan-induced eosinophilia-myalgia syndrome.
Leukopenia
Diffuse lymphadenopathy as the presenting manifestation of systemic lupus erythematosus.
Leukoplakia, Oral
The significance of serum aldolase in oral leukoplakia and cancer.
Liver Abscess, Amebic
A preliminary study of serum aldolase level in hepatic amoebiasis.
Studies on some serum enzyme levels in various liver diseases.
Liver Cirrhosis
Aldolase isoenzymes in liver cirrhosis and primary liver cell cancer.
Changes of aldolase and pyruvate kinase isoenzymes during liver cirrhosis induction with carbon tetrachloride and 2-acetylamino-fluorene.
Detection of autoantibody to aldolase B in sera from patients with troglitazone-induced liver dysfunction.
Liver Diseases
Aldolase A isoenzyme levels in serum and tissues of patients with liver diseases.
Alteration of aldolase isozymes in serum and tissues of patients with cancer and other diseases.
Decreased serum aldolase B levels in patients with malignant tumors.
Detection of autoantibody to aldolase B in sera from patients with troglitazone-induced liver dysfunction.
Human aldolase B serum levels: a marker of liver injury.
Quantitative analysis of aldolase A mRNA in liver discriminates between hepatocellular carcinoma and cirrhosis.
Serum aldolase isoenzymes in benign and malignant liver disease.
[ACTIVITY OF ALDOLASE AND TRANSAMINASE (SGOT AND SGPT) IN THE URINE IN LIVER DISEASES.]
[Changes in serum transaminases and aldolase during liver diseases.]
[Clinical studies on aldolase isozyme with special reference to cancer and liver diseases]
[Diagnostic significance of serum aldolase in liver diseases.]
[Immunological determination of aldolase isoenzyme in liver diseases]
[Significance of the temperature specificity of aldolase isoenzmes in the iagnosis of liver diseases]
[SORBITOL DEHYDROGENASE, FRUCTOSE-1-PHOSPHATE ALDOLASE AND MALATE DEHYDROGENASE ACTIVITY IN SOME LIVER DISEASES.]
[Studies on aldolase isoenzyme in liver diseases]
[Studies on the serum enzymes in liver diseases; the activity of phosphohexoisomerase, aldolase and alkaline phosphatase.]
[The activity of the blood aldolase in liver diseases; a new enzyme test.]
[The aldolase test in liver diseases and in other disease entities with hepatic involvement.]
Liver Failure, Acute
Acute liver failure in neonates with undiagnosed hereditary fructose intolerance due to exposure from widely available infant formulas.
Liver Neoplasms
ANOMALY OF ALDOLASE IN PRIMARY LIVER CANCER.
Human aldolase B subunit-specific radioimmunoassay.
In vivo library screening identifies the metabolic enzyme aldolase A as a promoter of metastatic lung colonization.
Loss-of-Function Genetic Screening Identifies Aldolase A as an Essential Driver for Liver Cancer Cell Growth Under Hypoxia.
[Aldolase and hexokinase in liver cancer cells]
[Biochemical and immunohistochemical studies on alteration of aldolase isozymes in rat liver in the process of hepatocarcinogenesis by administration of a diet containing 3'-methyl-4-dimethylaminoazobenzene]
[HEPATIC ALDOLASE ANOMALY IN THE COURSE OF PRIMARY CANCER OF THE LIVER.]
[Natural carcinogens: hepatic cancer in the rainbow trout, with special reference to aldolase activities]
Liver Neoplasms, Experimental
Purification of aldolase C from rat brain and hepatoma.
Lung Diseases, Interstitial
Clinical characteristics and change in the antibody titres of patients with anti-MDA5 antibody-positive inflammatory myositis.
Myalgia in Patients with Dermatomyositis and Polymyositis Is Attributable to Fasciitis Rather Than Myositis: A Retrospective Study of 32 Patients who Underwent Histopathological Examinations.
Lung Neoplasms
Aldolase A promotes proliferation and G1/S transition via the EGFR/MAPK pathway in non-small cell lung cancer.
Carcinoembryonic antigen mRNA analysis detects micrometastatic cells in blood from lung cancer patients.
Elevated transcriptional levels of aldolase A (ALDOA) associates with cell cycle-related genes in patients with NSCLC and several solid tumors.
Exosomes carrying ALDOA and ALDH3A1 from irradiated lung cancer cells enhance migration and invasion of recipients by accelerating glycolysis.
Feedback regulation of ALDOA activates the HIF-1?/MMP9 axis to promote lung cancer progression.
Glycoproteomic Analysis of Human Lung Adenocarcinomas Using Glycoarrays and Tandem Mass Spectrometry: Differential Expression and Glycosylation Patterns of Vimentin and Fetuin A Isoforms.
Human lung cancer antigens recognized by autologous antibodies: definition of a novel cDNA derived from the tumor suppressor gene locus on chromosome 3p21.3.
Immunochemical and immunohistochemical studies on three aldolase isozymes in human lung cancer.
Nonenzymatic function of Aldolase A downregulates miR-145 to promote the Oct4/DUSP4/TRAF4 axis and the acquisition of lung cancer stemness.
Therapeutic Targeting of Aldolase A Interactions Inhibits Lung Cancer Metastasis and Prolongs Survival.
[An immunohistochemical study on three aldolase isozymes in human lung cancer]
[Differential expression of genes that encode glycolysis enzymes in kidney and lung cancer in humans].
Lupus Erythematosus, Systemic
Proteomic analysis of autoantigens associated with systemic lupus erythematosus: Anti-aldolase A antibody as a potential marker of lupus nephritis.
Lupus Nephritis
Aldolase and adenosine deaminase activity in lymphocytes of patients with glomerulonephritis.
Lymphatic Metastasis
Aldolase A promotes epithelial-mesenchymal transition to increase malignant potentials of cervical adenocarcinoma.
High expression of Aldolase A predicts poor survival in patients with clear-cell renal cell carcinoma.
Lymphocytosis
[Behavior of the leukocytic aldolase activity in subjects of pediatric age with absolute lymphocytosis and neutrophilia.]
Lymphoma
Glycolytic biomarkers predict transformation in patients with follicular lymphoma.
Lymphoma, Non-Hodgkin
[Modification of cancer aldolase in mouse spleen reticulosarcoma]
Malaria
A brief review on biomarkers and proteomic approach for malaria research.
A large proportion of P. falciparum isolates in the Amazon region of Peru lack pfhrp2 and pfhrp3: implications for malaria rapid diagnostic tests.
Aldolase provides an unusual binding site for thrombospondin-related anonymous protein in the invasion machinery of the malaria parasite.
Bone marrow suppression and severe anaemia associated with persistent Plasmodium falciparum infection in African children with microscopically undetectable parasitaemia.
Clearance dynamics of lactate dehydrogenase and aldolase following antimalarial treatment for Plasmodium falciparum infection.
Co-reactivity of plasmodial histidine-rich protein 2 and aldolase on a combined immuno-chromographic-malaria dipstick (ICT) as a potential semi-quantitative marker of high Plasmodium falciparum parasitaemia.
Comparative study of modified quantitative buffy coat and two rapid tests in comparison with peripheral blood smear in malaria diagnosis in mumbai, India.
Country-wide assessment of the genetic polymorphism in Plasmodium falciparum and Plasmodium vivax antigens detected with rapid diagnostic tests for malaria.
Crystal structure of fructose-1,6-bisphosphate aldolase from the human malaria parasite Plasmodium falciparum.
Feasible choices in diagnostic methods of malaria.
Genetic variability in Plasmodium vivax aldolase gene in Korean isolates and the sensitivity of the Binax Now malaria test.
In vitro translation of Plasmodium falciparum aldolase is not initiated at an unusual site.
Initiation of translation at a UAG stop codon in the aldolase gene of Plasmodium falciparum.
Malaria rapid diagnostic tests: challenges and prospects.
Modeling the interaction between aldolase and the thrombospondin-related anonymous protein, a key connection of the malaria parasite invasion machinery.
Multiplex malaria antigen detection by bead-based assay and molecular confirmation by PCR shows no evidence of Pfhrp2 and Pfhrp3 deletion in Haiti.
Partial purification and characterization of a murine malaria parasite, Plasmodium berghei specific aldolase.
Performance of Antigen Concentration Thresholds for Attributing Fever to Malaria among Outpatients in Angola.
Plasmodium falciparum Parasitemia and Band Sensitivity of the SD Bioline Malaria Ag P.f/Pan Rapid Diagnostic Test in Madagascar.
Plasmodium glyceraldehyde-3-phosphate dehydrogenase: A potential malaria diagnostic target.
Recent Advances in the Development of Biosensors for Malaria Diagnosis.
Selective inhibition of Plasmodium falciparum aldolase by a tubulin derived peptide and identification of the binding site.
Stage-specific expression of aldolase isoenzymes in the rodent malaria parasite Plasmodium berghei.
The Binding of Plasmodium falciparum Adhesins and Erythrocyte Invasion Proteins to Aldolase Is Enhanced by Phosphorylation.
The Immunodetection of Non-Falciparum Malaria in Ancient Egyptian Bones (Giza Necropolis).
[Rapid diagnostic test for malaria].
Malaria, Falciparum
Clearance dynamics of lactate dehydrogenase and aldolase following antimalarial treatment for Plasmodium falciparum infection.
[Rapid diagnostic test for malaria].
Malaria, Vivax
Co-reactivity of plasmodial histidine-rich protein 2 and aldolase on a combined immuno-chromographic-malaria dipstick (ICT) as a potential semi-quantitative marker of high Plasmodium falciparum parasitaemia.
Malignant Catarrh
Single-chain antibody fragments from a display library derived from chickens immunized with a mixture of parasite and viral antigens.
Malnutrition
Alterations in rat brain glutaminase and aldolase induced by lead ingestion following malnutrition.
Effect of protein malnutrition on the glycolytic and glutaminolytic enzyme activity of rat thymus and mesenteric lymph nodes.
Medulloblastoma
Glycolytic enzymes from human neuroectodermal tumors of childhood.
Melanoma
Angiopoietin-like 4 promotes melanoma cell invasion and survival through aldolase A.
Detachment of the glycolytic enzymes, phosphofructokinase and aldolase, from cytoskeleton of melanoma cells, induced by local anesthetics.
Identification of melanoma antigens using a Serological Proteome Approach (SERPA).
Metastasis Suppressor NME1 Directly Activates Transcription of the ALDOC Gene in Melanoma Cells.
The melanoma brain metastatic microenvironment: aldolase C partakes in shaping the malignant phenotype of melanoma cells - a case of inter-tumor heterogeneity.
[Angiopoietin-like 4 modulates aldolase A expression in human melanoma cell in a PKC dependent manner].
Melanoma, Experimental
Detachment of glycolytic enzymes from cytoskeleton of melanoma cells induced by calmodulin antagonists.
Detachment of the glycolytic enzymes, phosphofructokinase and aldolase, from cytoskeleton of melanoma cells, induced by local anesthetics.
Proteomic study reveals a co-occurrence of gallic acid-induced apoptosis and glycolysis in B16F10 melanoma cells.
Meningitis
Cerebrospinal fluid aldolase, lactate and creatine phosphokinase in the differential diagnosis of meningitis and meningo-encephalitis.
[Cerebrospinal fluid aldolase level in children with meningitis]
[Diagnostic significance of glycolytic enzyme activity of aldolase and lactate dehydrogenase of the cerebrospinal fluid in meningitis]
[The diagnostic importance of determining cerebrospinal fluid aldolase activity in various forms of meningitis]
Meningitis, Bacterial
[Serum and cerebrospinal fluid enzyme spectra in meningitis and their differential diagnostic value]
Meningomyelocele
The present status of prenatal detection of neural tube defects.
Metabolic Diseases
Hereditary fructose intolerance: functional study of two novel ALDOB natural variants, and characterization of a partial gene deletion.
Implementation of a Targeted Next-Generation Sequencing Panel for Constitutional Newborn Screening in High-Risk Neonates.
Mutations in the promoter region of the aldolase B gene that cause hereditary fructose intolerance.
Social and health care needs in patients with hereditary fructose intolerance in Spain.
Metabolic Syndrome
Upregulation of aldolase B and overproduction of methylglyoxal in vascular tissues from rats with metabolic syndrome.
Mouth Neoplasms
Metabolic Regulation of Glycolysis and AMP Activated Protein Kinase Pathways during Black Raspberry-Mediated Oral Cancer Chemoprevention.
[Changes in serum aldolase in patients with oral cancer]
Movement Disorders
Erratum to: Proteomic identification of aldolase A as an autoantibody target in patients with atypical movement disorders.
Proteomic identification of aldolase A as an autoantibody target in patients with atypical movement disorders.
Multiple Myeloma
Serum aldolase in multiple myeloma.
[Clinical and experimental studies on aldolase and its isoenzymes in leukemia and allied hematological disorders (author's transl)]
Multiple Sclerosis
[Serum aldolase activity with special reference to multiple sclerosis, schizophrenia & alcoholism.]
Mumps
Pathology of carbohydrate metabolism in virus-infected cell cultures. I. Alterations of aldolase activity in cultures infected with vaccinia and mumps viruses.
Muscle Weakness
A Case of Advanced Lung Adenocarcinoma with Nvolumab-associated Dermatomyositis.
A case of Graves' disease associated with polymyositis.
Aberrant serum enzyme patterns in dermatomyositis associated with hepatoma.
Anti-MDA5 Antibody-positive Dermatomyositis Complicated by Autoimmune-associated Hemophagocytic Syndrome that was Successfully Treated with Immunosuppressive Therapy and Plasmapheresis.
Bronchiolitis Obliterans with Organizing Pneumonia (BOOP) Heralding Anti-Jo-1-Positive Polymyositis.
Chronic graft-versus-host disease manifesting as polymyositis: an uncommon presentation.
Classification criteria for polymyositis and dermatomyositis.
High Prevalence of Myositis in a Southeastern United States Pediatric Systemic Lupus Erythematosus Cohort.
Myalgia in Patients with Dermatomyositis and Polymyositis Is Attributable to Fasciitis Rather Than Myositis: A Retrospective Study of 32 Patients who Underwent Histopathological Examinations.
Phase II clinical trial of didemnin B in previously treated small cell lung cancer.
Severe cardiac involvement in children with systemic sclerosis and myositis.
[A case of amyopathic dermatomyositis with acute interstitial pneumonia (DAD pattern)]
[Clinical analysis of 11 cases of juvenile dermatomyositis and polymyositis]
[Coxsackie virus infection. Associated with myositis and polyarthritis]
[Intravenous cyclophosphamide pulse therapy for refractory juvenile dermatomyositis]
[Poisoning by adulterated edible oil]
[Rhabdomyolysis: clinical features, causes, complications and treatment]
Muscular Atrophy
Baseline Description of the Juvenile Localized Scleroderma Subgroup From the Childhood Arthritis and Rheumatology Research Alliance Legacy Registry.
[Muscular lesion due to insertion of needle (author's transl)]
Muscular Atrophy, Spinal
Investigations on enzyme activity in the serum and CSF of patients with neuromuscular diseases.
Muscular Diseases
A thermolabile aldolase A mutant causes fever-induced recurrent rhabdomyolysis without hemolytic anemia.
Aldolase predicts subsequent myopathy occurrence in systemic sclerosis.
Brief report: inherited metabolic myopathy and hemolysis due to a mutation in aldolase A.
Chronic Graft Versus Host Myopathies: Noninflammatory, Multi-Tissue Pathology With Glycosylation Disorders.
Combination of atorvastatin and gemfibrozil plus physical activity: an animal model of statin/fibrate-induced myopathy.
Epsilon aminocaproic acid (EACA) myopathy.
Evaluation of laboratory tests as a guide to diagnosis and therapy of myositis.
Glycogen storage diseases of muscle.
High Aldolase with Normal Creatine Kinase in serum predicts a Myopathy with Perimysial Pathology.
Inherited metabolic myopathy and hemolysis due to a mutation in aldolase A.
Interpretation of creatine kinase and aldolase for statin-induced myopathy: Reliance on serial testing based on biological variation.
Phase II clinical trial of didemnin B in previously treated small cell lung cancer.
Scleromyxedema myopathy: case report and review of the literature.
Serum aldolase and the diagnosis of myopathy.
The comparative utility of serum creatine kinase versus serum aldolase in the evaluation of muscle disorders.
[Aldolase]
[Elevation of the serum aldolase level; biochemical test in myopathy.]
[Enzymes and muscle diseases]
[Hypothyroid myopathy in a young adult]
[Poisoning by adulterated edible oil]
[Reevaluation of validity of percent creatinuria for diagnosing steroid myopathy]
[Serum aldolase activity in patients with myopathies and in their close reltives]
[Studies on the serum aldolase activity in workers with muscle disorders caused by vibration work]
[STUDY OF SERUM ALDOLASE IN MUSCULAR DISEASES.]
[Study of serum transaminase and aldolase levels in the course of myopathy.]
[Study of the level of serum transaminases and aldolase during myopathies.]
[The aldolase test in myopathies.]
[The diagnostic significance of the activity of aldolase in the blood serum of patients with myopathy.]
[The value and significance of changes of serum aldolase and creatine phosphokinase in muscular diseases]
Muscular Dystrophies
Aldolase activity in the plasma or serum of normal children and families with muscular dystrophy.
Aldolase isoenzymes in serum and muscle from patients with progressive muscular dystrophy and from human foetus.
Aldolase leak from muscle of mice with hereditary muscular dystrophy.
Malignant hyperpyrexia. A study of an affected family.
Management of muscular dystrophy during osteoarthritis disorder: A topical phytotherapeutic treatment protocol.
Muscle and serum enzymes and isoenzymes in muscular dystrophies.
Plasma aldolase and glutamic-oxaloacetic transaminase activities in inherited muscular dystrophy of domestic chicken.
Serine protease in mice with hereditary muscular dystrophy.
Serum aldolase and phosphocreatine kinase in umbilical cord blood.
Serum aldolase in muscular dystrophies, neuromuscular disorders, and wasting of skeletal muscle.
[Aldolase acitivity in subcellular muscle particles in experimental muscular dystrophy and in normal conditions]
[Aldolase activity of the blood in patients with progressive muscular dystrophy.]
[Aldolase, GOT and LDH activity of the serum in progressive muscular dystrophy and myotonic dystrophy.]
[Aldolase]
[Behavior of aldolase activity in vitamin E-deficient rats with muscular dystrophy.]
[Characterization, by chromatography on DEAE-sephadex, of fructose-1,6-diphosphate aldolase of normal adult and fetal muscle and muscle of subjects with progressive muscular dystrophy of the Duchenne type]
[Comparative studies of the properties of aldolase isoenzymes A-C in normal rabbit brain and in skeletal muscles from rabbits with E-avitaminosis dystrophy]
[DIAGNOSTIC SIGNIFICANCE OF THE SERUM ALDOLASE ACTIVITY IN PROGRESSIVE MUSCULAR DYSTROPHY IN CHILDHOOD.]
[Enzymes and muscle diseases]
[Erythrocytic glycolysis & aldolase in muscular dystrophy.]
[Isoenzymes of fructose phosphate aldolase in patients with progressive muscular dystrophy]
[Preparation and application of control sera for neuromuscular disorders]
[Serum aldolase and creatine phosphokinase in progressive muscular dystrophy]
[Serum enzyme dynamics in progressive muscular dystrophies]
[Significance of the increase of aldolase in blood in muscular dystrophy.]
[The activity of serum aldolase in progressive muscular dystrophy.]
[THE BEHAVIOR OF SERUM ALDOLASE AND TRANSAMINASE ACTIVITY IN PROGRESSIVE MUSCULAR DYSTROPHY IN BASIC CONDITIONS AND AFTER ANABOLIC AND RE-METABOLIZING THERAPY.]
Muscular Dystrophy, Duchenne
Activity of serum aldolase and lactic dehydrogenase in patients affected with Duchenne muscular dystrophy and in their immediate relatives.
Sarcoplasmic reticulum Ca2+-ATPase and acylphosphatase activities in muscle biopsies from patients with Duchenne muscular dystrophy.
[Enzyme diagnosis in progressive muscular dystrophies, especially in the Duchenne type]
Myalgia
Effects of amino acid supplementation on muscle soreness and damage.
High Prevalence of Myositis in a Southeastern United States Pediatric Systemic Lupus Erythematosus Cohort.
Myalgia in Patients with Dermatomyositis and Polymyositis Is Attributable to Fasciitis Rather Than Myositis: A Retrospective Study of 32 Patients who Underwent Histopathological Examinations.
Potential therapeutic effects of branched-chain amino acids supplementation on resistance exercise-based muscle damage in humans.
Serum aldolase and lactate dehydrogenase levels in the eosinophilia myalgia syndrome.
Variability in serum creatine kinase response after eccentric exercise of the elbow flexors.
[A case of fulminant psittacosis showing Chlamydia in TBLB specimens]
[Chronic GVHD with polymyositis after non-myeloablative stem cell transplantation]
[Coxsackie virus infection. Associated with myositis and polyarthritis]
Myocardial Infarction
Glutamic-oxalacetic transaminase in the diagnosis of myocardial infarction. II. Comparison of serum transaminase activity with determinations of serum aldolase, cholesterol, alpha2-globulin, iron, copper and lactic dehydrogenase.
Plasma fibrinogen and serum aldolase in acute myocardial infarction.
Serum aldolase in acute myocardial infarction.
The serum aldolase level in acute myocardial infarction.
[Activity and isoenzyme patterns of fructosephosphate aldolase in the serum of dogs with experimental myocardial infarction]
[Aldolase of the blood in patients with myocardial infarct.]
[Characteristics of the molecular diversities of human and rat aldolase via starch and agar gel electrophoresis]
[Contribution to the diagnosis of myocardial infarct. III. Variations of serum aldolase in acute myocardial infarct.]
[CRITICAL EVALUATION OF THE DETERMINATION OF GOT, GPT AND ALDOLASE IN THE DIAGNOSIS OF MYOCARDIAL INFARCTION.]
[Determination of aldolase A activity in the serum of patients with myocardial infarction]
[IMPORTANCE OF DETERMINING THE ACTIVITY OF GLUTAMIC OXALACETIC TRANSAMINASE, ALDOLASE AND C-REACTIVE PROTEIN FOR THE DIFFERENTIATION OF MACRO- AND MICROFOCAL MYOCARDIAL INFARCT AND STENOCARDIA.]
[Liver-specific enzymatic activity and radiohepatographic indices in evaluating the functional state of the liver in myocardial infarct]
[Studies on the behavior of glutamicaceto-oxalic transaminase, aldolase and c-reactive proteins in myocardial infarction.]
[Type A aldolase activity of the serum of myocardial infarct patients]
Myocardial Ischemia
[Determination of aldolase A activity in the serum of patients with myocardial infarction]
[Diagnostic coefficients of ischemic heart disease in diabetes mellitus]
Myocarditis
Correction: Elevated aldolase 1A, retrogene 1 expression induces cardiac apoptosis in rat experimental autoimmune myocarditis model.
Elevated Aldolase 1A, retrogene 1 expression induces cardiac apoptosis in rat experimental autoimmune myocarditis model.
Serum aldolase and electrocardiographic changes in diphtheritic myocarditis.
Myoclonus
Why do Purkinje cells die so easily after global brain ischemia? Aldolase C, EAAT4, and the cerebellar contribution to posthypoxic myoclonus.
[A mitochondrial encephalomyopathy due to partial cytochrome c oxidase deficiency with giant evoked potentials--a case report]
Myoglobinuria
Acute renal failure due to nontraumatic rhabdomyolysis.
Acute renal failure in severe exertional rhabdomyolysis.
Tsutsugamushi infection-associated acute rhabdomyolysis and acute renal failure.
[Investigation of etiologies for acute renal failure due to rhabdomyolysis in 5 patients]
Myositis
Aldolase in the diagnosis of myositis.
Assessment of Optimal Screening Tests for the Detection of an Inflammatory Myositis-associated Interstitial Lung Disease.
Classification criteria for polymyositis and dermatomyositis.
High Prevalence of Myositis in a Southeastern United States Pediatric Systemic Lupus Erythematosus Cohort.
Isolated elevated aldolase as a marker for a myositis subtype: another branch to the polymyositis tree.
Isolated elevation of aldolase in the serum of myositis patients: a potential biomarker of damaged early regenerating muscle cells.
Sarcoidosis patient with lupus pernio and infliximab-induced myositis: Response to Acthar gel.
The Utility of Shear-Wave Elastography in the Evaluation of Myositis.
[A case of fulminant psittacosis showing Chlamydia in TBLB specimens]
Myotonia
Effect of myotonia induced by anthracene-9-carboxylic acid on mitochondrial calcium, plasma creatinine-phosphokinase and aldolase activity in the rat.
Phase II clinical trial of didemnin B in previously treated small cell lung cancer.
Myotonia Congenita
Myotonias and army personnel: symptoms and effects on service fitness.
Myotonic Dystrophy
Human muscle carbonic anhydrase III (CA-III). Purification, immunohistochemical localization in the human skeletal muscle and its clinical application to the neuromuscular disease.
[Aldolase determinations in the serum in myotonic dystrophy.]
[Aldolase, GOT and LDH activity of the serum in progressive muscular dystrophy and myotonic dystrophy.]
Neoplasm Metastasis
ALDOA functions as an oncogene in the highly metastatic pancreatic cancer.
ALDOB promotes liver metastases development.
Aldolase A as a prognostic factor and mediator of progression via inducing epithelial-mesenchymal transition in gastric cancer.
Aldolase A overexpression is associated with poor prognosis and promotes tumor progression by the epithelial-mesenchymal transition in colon cancer.
Aldolase A promotes epithelial-mesenchymal transition to increase malignant potentials of cervical adenocarcinoma.
Aldolase B inhibits metastasis through Ten-Eleven Translocation 1 and serves as a prognostic biomarker in hepatocellular carcinoma.
Aldolase B Overexpression is Associated with Poor Prognosis and Promotes Tumor Progression by Epithelial-Mesenchymal Transition in Colorectal Adenocarcinoma.
Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis.
Aldolase triggers metabolic reprogramming in colorectal cancer in hypoxia and stiff desmoplastic microenvironments.
Clinical-translational approaches to the Nm23-H1 metastasis suppressor.
Enzymatic tests in the prognosis and course controls in bronchial carcinoma patients.
Feedback regulation of ALDOA activates the HIF-1?/MMP9 axis to promote lung cancer progression.
Fructose-bisphosphate aldolase a is a potential metastasis-associated marker of lung squamous cell carcinoma and promotes lung cell tumorigenesis and migration.
Glycolytic enzyme activities in breast cancer metastases.
Heterogeneity of glycolytic enzyme activity and isozyme composition of pyruvate kinase in breast cancer.
High expression of aldolase A is associated with tumor progression and poor prognosis in hepatocellular carcinoma.
High expression of Aldolase A predicts poor survival in patients with clear-cell renal cell carcinoma.
High expression of fructose-bisphosphate aldolase A induces progression of renal cell carcinoma.
Human aldolase B serum levels: a marker of liver injury.
Human aldolase B subunit-specific radioimmunoassay.
Icariside II from Epimedium koreanum inhibits hypoxia-inducible factor-1alpha in human osteosarcoma cells.
Role of aldolase A in osteosarcoma progression and metastasis: in vitro and in vivo evidence.
Selective treatment pressure in colon cancer drives the molecular profile of resistant circulating tumor cell clones.
The ALDOA Metabolism Pathway as a Potential Target for Regulation of Prostate Cancer Proliferation.
Therapeutic Targeting of Aldolase A Interactions Inhibits Lung Cancer Metastasis and Prolongs Survival.
[Determination of aldolase A by radioimmunoassay. Experimental and clinical studies on the diagnosis of cancer of the digestive tract]
[Relevance of serum aldolase for the detection of liver metastases of bronchial cancer--comparative enzymatic and endoscopy-autopsy studies]
[The value determination of serum aldolase for findings of metastases and relapses on bronchial carcinoma (author's transl)]
Neoplasms
A Fluorescence-Based High-Throughput Assay for the Identification of Anticancer Reagents Targeting Fructose-1,6-Bisphosphate Aldolase.
A new human species of aldolase A mRNA from fibroblasts.
A novel lncRNA ARST represses glioma progression by inhibiting ALDOA-mediated actin cytoskeleton integrity.
A Robust and Cost-Effective Luminescent-Based High-Throughput Assay for Fructose-1,6-Bisphosphate Aldolase A.
Aberrant expression of the glycolytic enzymes aldolase B and type II hexokinase in hepatocellular carcinoma are predictive markers for advanced stage, early recurrence and poor prognosis.
Aberrant lactate dehydrogenase A signaling contributes metabolic signatures in pancreatic cancer.
Accumulation of fructose 1,6-bisphosphate protects clear cell renal cell carcinoma from oxidative stress.
Activity of glycolytic enzymes and glucose-6-phosphate dehydrogenase in lipoblastic and neurogenic proliferations.
Activity of glycolytic enzymes and glucose-6-phosphate dehydrogenase in smooth muscle proliferation.
Aldolase A as a prognostic factor and mediator of progression via inducing epithelial-mesenchymal transition in gastric cancer.
Aldolase A Enhances Intrahepatic Cholangiocarcinoma Proliferation and Invasion through Promoting Glycolysis.
Aldolase A overexpression is associated with poor prognosis and promotes tumor progression by the epithelial-mesenchymal transition in colon cancer.
Aldolase A promotes epithelial-mesenchymal transition to increase malignant potentials of cervical adenocarcinoma.
ALDOLASE A regulates invasion of bladder cancer cells via E-cadherin-EGFR signaling.
Aldolase B impairs DNA mismatch repair and induces apoptosis in colon adenocarcinoma.
Aldolase B inhibits metastasis through Ten-Eleven Translocation 1 and serves as a prognostic biomarker in hepatocellular carcinoma.
Aldolase B Overexpression is Associated with Poor Prognosis and Promotes Tumor Progression by Epithelial-Mesenchymal Transition in Colorectal Adenocarcinoma.
Aldolase B-Mediated Fructose Metabolism Drives Metabolic Reprogramming of Colon Cancer Liver Metastasis.
Aldolase C in neuroendocrine tumors: an immunohistochemical study.
Aldolase isoenzymes in liver cirrhosis and primary liver cell cancer.
Aldolase isozyme patterns in the liver of patients with malignant tumor in the stomach or esophagus.
Aldolase isozyme patterns of representative tumours in the human nervous system.
Aldolase isozymes in cancer.
Aldolase isozymes in human tissue and serum. With special reference to cancer diagnosis.
Aldolase isozymes in rat tumor cells.
Aldolase triggers metabolic reprogramming in colorectal cancer in hypoxia and stiff desmoplastic microenvironments.
Aldolase-DNA interactions in a SEWA cell system.
Alteration of aldolase isozymes in serum and tissues of patients with cancer and other diseases.
An immunochemical and immunohistochemical study of aldolase isozymes in renal cell carcinoma.
An immunohistochemical study of aldolase C in normal and neoplastic nervous tissues.
Biochemical and clinical studies of aldolase isozymes in human cancer.
Bisphosphonate inhibitors of mammalian glycolytic aldolase.
C/D-Box Snord105b Promotes Tumorigenesis in Gastric Cancer via ALDOA/C-Myc Pathway.
Carcinoembryonic antigen mRNA analysis detects micrometastatic cells in blood from lung cancer patients.
Chemical adaptor immunotherapy: design, synthesis, and evaluation of novel integrin-targeting devices.
Clinical Relevance of Gene Copy Number Variation in Metastatic Clear Cell Renal Cell Carcinoma.
Computational and Experimental Studies of Inhibitor Design for Aldolase A.
Decreased serum aldolase B levels in patients with malignant tumors.
Definition of a Novel Feed-Forward Mechanism for Glycolysis-HIF1? Signaling in Hypoxic Tumors Highlights Aldolase A as a Therapeutic Target.
Dermatomyositis and malignancy in Tunisia: a multicenter national retrospective study of 20 cases.
Diagnosis of cancer by radioimmunoassay of muscle type aldolase.
Dominant-negative hypoxia-inducible factor-1 alpha reduces tumorigenicity of pancreatic cancer cells through the suppression of glucose metabolism.
Efficacy of Terminalia arjuna (Roxb.) on N-nitrosodiethylamine induced hepatocellular carcinoma in rats.
Elevated levels of serum aldolase A in patients with renal cell carcinoma.
Elevated transcriptional levels of aldolase A (ALDOA) associates with cell cycle-related genes in patients with NSCLC and several solid tumors.
Enzyme activities in normal, dysplastic, and cancerous human breast tissues.
Enzymes of glucose metabolism in carcinoma of the cervix and endometrium of the human uterus.
Evaluation of nontumorous tissue damage by transcatheter arterial embolization for hepatocellular carcinoma.
Fructose-1,6-Bisphosphate Aldolase B Depletion Promotes Hepatocellular Carcinogenesis Through Activating Insulin Receptor Signaling and Lipogenesis.
Fructose-bisphosphate aldolase A is a key regulator of hypoxic adaptation in colorectal cancer cells and involved in treatment resistance and poor prognosis.
Fructose-Bisphosphate Aldolase A Regulates Hypoxic Adaptation in Hepatocellular Carcinoma and Involved with Tumor Malignancy.
Glyceraldehyde-3-phosphate, a glycolytic intermediate, plays a key role in controlling cell fate via inhibition of caspase activity.
Glycolytic enzyme activities in breast cancer metastases.
Glycolytic enzymes from human neuroectodermal tumors of childhood.
Heterogeneity of glycolytic enzyme activity and isozyme composition of pyruvate kinase in breast cancer.
High expression of ALDOA and DDX5 are associated with poor prognosis in human colorectal cancer.
High expression of aldolase A is associated with tumor progression and poor prognosis in hepatocellular carcinoma.
High expression of Aldolase A predicts poor survival in patients with clear-cell renal cell carcinoma.
High Expression of Aldolase B Confers a Poor Prognosis for Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy.
High expression of fructose-bisphosphate aldolase A induces progression of renal cell carcinoma.
Histological examination of the aldolase monomer composition of cells from human kidney and hypernephroid carcinoma.
Human aldolase A gene: structural organization and expression in tumor cell lines.
Human aldolase B serum levels: a marker of liver injury.
Human aldolase B subunit-specific radioimmunoassay.
Hypoxia-inducible factor 1 activation by aerobic glycolysis implicates the Warburg effect in carcinogenesis.
Identification and characterization of a gibberellin-regulated protein, which is ASR5, in the basal region of rice leaf sheaths.
Identification of aldolase A as a potential diagnostic biomarker for colorectal cancer based on proteomic analysis using formalin-fixed paraffin-embedded tissue.
Identification of altered protein expression and post-translational modifications in primary colorectal cancer by using agarose two-dimensional gel electrophoresis.
Identification of developmental competence-related genes in mature porcine oocytes.
Identification of elicitor-responsive proteins in rice leaves by a proteomic approach.
Immunochemical and immunohistochemical studies on three aldolase isozymes in human lung cancer.
Importance of determinations of serum hexokinase, aldolase, and lactate dehydrogenase activities, and of the lactate/pyruvate-quotient in the diagnosis of malignant tumors.
In vivo library screening identifies the metabolic enzyme aldolase A as a promoter of metastatic lung colonization.
Isozyme patterns of normal, benign, and malignant human breast tissues.
Location of adult and fetal aldolases A, B, and C by immunoperoxidase technique in LF fast-growing rat hepatomas.
Long noncoding RNA DIO3OS interacts with miR-122 to promote proliferation and invasion of pancreatic cancer cells through upregulating ALDOA.
Loss of alanine-glyoxylate and serine-pyruvate aminotransferase expression accelerated the progression of hepatocellular carcinoma and predicted poor prognosis.
Loss of hepatic aldolase B activates Akt and promotes hepatocellular carcinogenesis by destabilizing the Aldob/Akt/PP2A protein complex.
Loss-of-Function Genetic Screening Identifies Aldolase A as an Essential Driver for Liver Cancer Cell Growth Under Hypoxia.
Malignant pleural effusion cells show aberrant glucose metabolism gene expression.
Metabolic tumor burden is associated with major oncogenomic alterations and serum tumor markers in patients with resected pancreatic cancer.
miR-122-5p Inhibits the Proliferation, Invasion and Growth of Bile Duct Carcinoma Cells by Targeting ALDOA.
Muscle-type aldolase isolated from a liver tumor.
Myalgia in Patients with Dermatomyositis and Polymyositis Is Attributable to Fasciitis Rather Than Myositis: A Retrospective Study of 32 Patients who Underwent Histopathological Examinations.
Nonenzymatic function of Aldolase A downregulates miR-145 to promote the Oct4/DUSP4/TRAF4 axis and the acquisition of lung cancer stemness.
Prodrugs of dynemicin analogs for selective chemotherapy mediated by an aldolase catalytic Ab.
Promoter Mutation Analysis of ALDOA Gene in Solid Tumors and Acute Leukemias.
Radioimmunoassay of aldolase A. Determination of normal serum levels and increased serum concentration in cancer patients.
Resurgence of fetal isozymes in cancer: study of aldolase, pyruvate kinase, lactic dehydrogenase, and beta-hexosaminidase.
Role of aldolase A in osteosarcoma progression and metastasis: in vitro and in vivo evidence.
Roles of Aldolase Family Genes in Human Cancers and Diseases.
Selective treatment pressure in colon cancer drives the molecular profile of resistant circulating tumor cell clones.
Serum aldolase and its relationship to the hormonal control of cancer.
Serum enzyme activity in bone tumors and osteomyelitis (LDH, GOT, GPT, CPK, CHE, ALP, AP, PP, ALD).
Sheep gene mapping: assignment of ALDOB, CYP19, WT and SOX2 by somatic cell hybrid analysis.
Significance of serum phosphohexose isomerase, hexokinase and aldolase in carcinoma ovary.
Significance of serum tumor markers in patients with carcinoma of the ovary.
Staining of bladder tumor cell dehydrogenase.
Studies on glycolytic enzymes in relation to cancer. 3. Clinical significance of serum phosphohexose isomerase and aldolase in cancer of the prostate. A comparative study with serum acid phosphatase and serum alkaline phosphatase.
Studies on glycolytic enzymes in relation to cancer. I. Serum phosphohexose isomerase and aldolase in leukemia.
Studies on glycolytic enzymes in relation to cancer. Part IV: Sera and effusion activities of phosphohexose isomerase, aldolase and lactic dehydrogenase in malignant and benign conditions.
Studies on isoenzymes in relation to cancer. II: Serum aldolase isoenzyme patterns in the diagnosis of primary hepatocellular carcinoma.
Subunit-specific radioimmunoassay for aldolase A, B, and C subunits: clinical significance.
Synthesis and evaluation of the aldolase antibody-derived chemical-antibodies targeting ?5?1 integrin.
Targeting a moonlighting function of aldolase induces apoptosis in cancer cells.
Targeting of several glycolytic enzymes using RNA interference reveals aldolase affects cancer cell proliferation through a non-glycolytic mechanism.
The ALDOA Metabolism Pathway as a Potential Target for Regulation of Prostate Cancer Proliferation.
The antitumor role of a newly discovered ?-d-glucan from Holotrichia diomphalia Bates as a selective blocker of aldolase A.
The CIMP-high phenotype is associated with energy metabolism alterations in colon adenocarcinoma.
The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance.
The significance of serum aldolase in oral leukoplakia and cancer.
The studies on glycolytic enzymes in relation to cancer. II. Comparative study of phosphohexose-isomerase, aldolase, isocitric dehydrogenase, serum glutamic oxaloacetic and pyruvic transaminase, and alkaline phosphatase in liver.
Therapeutic effect of tamoxifen and energy-modulating vitamins on carbohydrate-metabolizing enzymes in breast cancer.
Therapeutic Targeting of Aldolase A Interactions Inhibits Lung Cancer Metastasis and Prolongs Survival.
Threonine modulates immune response, antioxidant status and gene expressions of antioxidant enzymes and antioxidant-immune-cytokine-related signaling molecules in juvenile blunt snout bream (Megalobrama amblycephala).
Upregulation of the ALDOA/DNA-PK/p53 pathway by dietary restriction suppresses tumor growth.
Use of FDP and F1P aldolase to detect tumorous and nontumorous tissue damage by ethanol injection of hepatocellular carcinoma.
Use of fructose 1,6-diphosphate aldolase to detect tumour necrosis after transcatheter arterial embolization of hepatocellular carcinoma.
Use of serum gamma-enolase and aldolase A in combination as markers for renal cell carcinoma.
YC-1: a potential anticancer drug targeting hypoxia-inducible factor 1.
[A preliminary study on the gene expression of aldolase isozymes and chromatin composition and transcription in Ehrlich ascites tumor and the host liver]
[Aldolase activity in gynecologic patients with malignant neoplasms]
[Aldolase activity in human and animal tumors]
[Aldolase isozyme gene: on the structure and the tissue-specific expression of a muscle type aldolase gene]
[Aldolase isozymes in several tumor tissues of the rat]
[Aldolase, dipeptidase, tripeptidase, tributyrinase, phosphatase, amylase, proteins and protein polysaccharides in the blood serum and ascites fluid in the mouse ascites tumor.]
[Aldolase]
[An immunohistochemical study on three aldolase isozymes in human lung cancer]
[Anti-cancer activity of Zuojinwan in vivo and influence to tumor markers in mice transplanted with sarcoma 180]
[Biochemical and histochemical studies of fructosephosphate aldolase in tumors of the nervous system. Isoenzymes of fructosephosphate aldolase. 8]
[Biochemical and immunohistochemical studies on alteration of aldolase isozymes in rat liver in the process of hepatocarcinogenesis by administration of a diet containing 3'-methyl-4-dimethylaminoazobenzene]
[Biochemical and immunological examinations in patients with lung diseases under particular consideration of bronchial carcinoma (author's transl)]
[Biochemical investigation on aldolase in tumor tissues of the head and neck]
[Biosynthesis of muscle aldolase and muscle tumors in rats]
[Changes in the serum asparatand alanine transaminasae, phosphomonoesterase I and fructose 1-6 diphosphate aldolase in the preoperative and postoperative period of patients with cholelithiasis and cancer of the pancreas]
[Clinical significance of tissue and serum aldolase isozyme, with special reference to cancer]
[Clinical studies on aldolase isozyme with special reference to cancer and liver diseases]
[Clinical study on aldolase isoenzyme--the development of the method of cancer diagnosis with muscle type aldolase (author's transl)]
[Correlation of blood-chemistry changes and development of cancer in experimental tumor induction in the colon of rats]
[Critical observations on the value of serum lactic dehydrogenase and serum aldolase determination in the diagnosis of cancer.]
[Desoxyriboso-5-phosphate aldolase in the blood of normal subjects and cancer patients]
[Determination of aldolase A by radioimmunoassay. Experimental and clinical studies on the diagnosis of cancer of the digestive tract]
[Diagnosis of cancer by aldolase isoenzyme analysis]
[Diagnostic value of biochemical tumor markers in serum of patients with cancer of the ovary]
[Differential expression of genes that encode glycolysis enzymes in kidney and lung cancer in humans].
[Effect of Rhodotorula rubra yeast mannan on the molecular heterogeneity of rat blood serum aldolase in the dynamics of tumor growth]
[Glucose-6-phosphatase and aldolase in primary liver tumors induced by diethylnitrosamine]
[Glutamic oxalacetic, pyruvic transaminases and aldolase in neoplasms]
[HEPATIC ALDOLASE ANOMALY IN THE COURSE OF PRIMARY CANCER OF THE LIVER.]
[Immunohistological localization of human aldolase A in human neoplastic and non-neoplastic tissues]
[Importance of aldolase studies in cancer of the prostate]
[Isoenzymes of fructose phosphate aldolase in the serum of rats with liver tumors induced by diethylnitrosamine]
[Isoenzymes of fructosephosphate aldolase in patients with tumors of the urogenital system. XII. Isoenzymes of fructosephosphate aldolase]
[Modification of cancer aldolase in mouse spleen reticulosarcoma]
[Modifications of serum aldolase in patients with benign and malignant neoplasms.]
[On the behavior of some enzymatic activities in neoplastic tissues (glutamic-oxalacetic transaminases, glutamic-pyruvic transaminases, aldolase, lactic hydrogenase and malic dehydrogenase). II. Neoplasms of the digestive tract.]
[On the behavior of some enzymatic activities of neoplastic tissues (glutamic-oxalacetic transaminases, glutamic-pyruvic transaminases, aldolase, lactic hydrogenase and malic dehydrogenase). I. Breast neoplasms.]
[On the variations in the aldolase and glutamic-pyruvic transaminase index in subjects with neoplasms and in radiotherapeutic treatment.]
[Plasma aldolase activity in radium therapy of cancer of the uterus.]
[Proteome study of colorectal cancer genesis and hepatic metastasis]
[Relevance of serum aldolase for the detection of liver metastases of bronchial cancer--comparative enzymatic and endoscopy-autopsy studies]
[Screening and preliminary analysis of colorectal carcinoma-associated antigen genes.]
[SERUM ALDOLASE ACTIVITY IN PATIENTS WITH TUMORS.]
[Serum aldolase levels in patients with neoplasms]
[The distribution of the aldolase isoenzymes in various human tissues and the anomaly in cancerous tissues -especially in gastric cancer- (author's transl)]
[Tumor marker--present and future]
Neoplastic Cells, Circulating
Aldolase B inhibits metastasis through Ten-Eleven Translocation 1 and serves as a prognostic biomarker in hepatocellular carcinoma.
Nephritis
Proteomic analysis of autoantigens associated with systemic lupus erythematosus: Anti-aldolase A antibody as a potential marker of lupus nephritis.
Nephrosis
[Glycolytic activity in experimental nephrosis induced by anti-kidney serum. I. Aldolase; phosphoglucomutase.]
Nervous System Diseases
Highly sensitive enzyme immunoassay for human brain aldolase C.
Immunoreactive aldolase C in cerebrospinal fluid of patients with neurological disorders.
[Cerebrospinal fluid level of aldolase C in patients with various neurological disorders: comparison with neuron-specific enolase, S-100b protein and creatine kinase BB isoenzyme]
Nervous System Neoplasms
[Biochemical and histochemical studies of fructosephosphate aldolase in tumors of the nervous system. Isoenzymes of fructosephosphate aldolase. 8]
Neuroblastoma
Altered enzyme expression in "differentiated" murine neuroblastoma cells.
Cis-acting elements in the promoter region of the human aldolase C gene.
Glycolytic enzymes from human neuroectodermal tumors of childhood.
The transcription of the human fructose-bisphosphate aldolase C gene is activated by nerve-growth-factor-induced B factor in human neuroblastoma cells.
Neurodegenerative Diseases
Differential transport and local translation of cytoskeletal, injury-response, and neurodegeneration protein mRNAs in axons.
Neuroendocrine Tumors
Aldolase C in neuroendocrine tumors: an immunohistochemical study.
Neuromuscular Diseases
Aldolase isoenzymes in the serum of patients with neuromuscular diseases.
Human muscle carbonic anhydrase III (CA-III). Purification, immunohistochemical localization in the human skeletal muscle and its clinical application to the neuromuscular disease.
Investigations on enzyme activity in the serum and CSF of patients with neuromuscular diseases.
[Aldolase activity of blood in neuromuscular diseases.]
[Serum enzymatic activity in neuromuscular diseases]
Non-alcoholic Fatty Liver Disease
Non-alcoholic fatty liver in hereditary fructose intolerance.
Obesity
Differential representation of liver proteins in obese human subjects suggests novel biomarkers and promising targets for drug development in obesity.
Opisthorchiasis
[Effect of chloxyl on the content of aldolase and transaminases and certain indicators of blood coagulation in opisthorchiasis]
Osteomyelitis
Serum enzyme activity in bone tumors and osteomyelitis (LDH, GOT, GPT, CPK, CHE, ALP, AP, PP, ALD).
Osteosarcoma
LncRNA KCNQ1OT1 sponges miR-34c-5p to promote osteosarcoma growth via ALDOA enhanced aerobic glycolysis.
Proteomic investigation of resistance to chemotherapy drugs in osteosarcoma.
Proteomic profiling of osteosarcoma cells identifies ALDOA and SULT1A3 as negative survival markers of human osteosarcoma.
Role of aldolase A in osteosarcoma progression and metastasis: in vitro and in vivo evidence.
Ovarian Neoplasms
Down-regulation of Ras-related protein Rab 5C-dependent endocytosis and glycolysis in cisplatin-resistant ovarian cancer cell lines.
[Diagnostic value of determination of the content of glucose, aldolase and lactic acid in the blood serum and exudate from the abdominal cavity in ovarian neoplasms]
Pancreatic Neoplasms
ALDOA functions as an oncogene in the highly metastatic pancreatic cancer.
Long noncoding RNA DIO3OS interacts with miR-122 to promote proliferation and invasion of pancreatic cancer cells through upregulating ALDOA.
Proteomic analysis of pancreatic ductal adenocarcinoma compared with normal adjacent pancreatic tissue and pancreatic benign cystadenoma.
The growth inhibitory effect of gambogic acid on pancreatic cancer cells.
[Changes in the serum asparatand alanine transaminasae, phosphomonoesterase I and fructose 1-6 diphosphate aldolase in the preoperative and postoperative period of patients with cholelithiasis and cancer of the pancreas]
Pancreatitis
[Determination of serum aldolase value in affected by pancreatitis]
[Fructosediphosphate aldolase activity in the tissues and blood of rats at various stages in the development of experimental pancreatitis]
[Serum glutamic acid oxalacetic acid transaminase and aldolase in acute pancreatitis.]
[Values of aldolase and serum transaminase in acute pancreatitis]
Papillomavirus Infections
[Specific features of a change in some blood biochemical indicators in virus urogenital infections].
Paralysis
A mutation in Drosophila Aldolase Causes Temperature-Sensitive Paralysis, Shortened Lifespan, and Neurodegeneration.
Parasitic Diseases
Studies with type I aldolase to understand fructose intolerance and combat parasitic disease.
Periodontal Diseases
[ATP, phosphatases and aldolase in the supragingival dental calculus, dental deposit and salvia in parodontosis]
Peripheral Nervous System Diseases
[Clinical study on jinmaitong composita on diabetic peripheral neuropathy]
Peritonitis
[Aldolase activity of lymph and blood serum in experimental peritonitis]
Pheochromocytoma
Aldolase C in neuroendocrine tumors: an immunohistochemical study.
Human aldolase C gene expression is regulated by adenosine 3',5'-cyclic monophosphate (cAMP) in PC12 cells.
phosphoglycerate kinase deficiency
Red cell enzymopathies as a model of inborn errors of metabolism.
Plague
[The serologic relationship of plague microbe aldolase to aldolases of other types of bacteria]
Pneumonia
[Catalase, glutathione and aldolase of blood in acute pneumonia of young children]
[Changes in the activity of proteolytic enzymes, aldolase and aminotransferases in young children with acute pneumonia in a hot climate]
[Phosphohexose isomerase and aldolase of the blood serum in pneumonia in children]
Poliomyelitis
Studies on serum aldolase and lactic dehydrogenase in poliomyelitis.
Polycythemia
[Aldolase, lactic dehydrogenase, and glutamic oxalacetic transaminase activity in plasma and erythrocytes in polyglobulia and polycythemia.]
Polymyositis
Aldolase levels in dermatomyositis and polymyositis with normal creatine kinase levels.
Chronic recurrent multifocal osteomyelitis with interstitial myositis.
Isolated elevated aldolase as a marker for a myositis subtype: another branch to the polymyositis tree.
Severe cardiac involvement in children with systemic sclerosis and myositis.
[Aldolase]
[Enzymes and muscle diseases]
Precursor Cell Lymphoblastic Leukemia-Lymphoma
[Blood serum aldolase level in children with lymphoblastic leukemia and Hodgkin's disease]
Prostatic Hyperplasia
Aldolase activity in benign prostatic hypertrophy and adenocarcinomatous prostate.
[The value of enzyme determinations in the differential diagnosis of prostatic hypertrophy and carcinoma. Parallel evaluation of the behavior of acid phosphatases, aldolase, malic and lactic dehydrogenases.]
Prostatic Neoplasms
Biologic titration of diethylstilbestrol against activity of prostatic cancer: effect on serum aldolase.
Studies on glycolytic enzymes in relation to cancer. 3. Clinical significance of serum phosphohexose isomerase and aldolase in cancer of the prostate. A comparative study with serum acid phosphatase and serum alkaline phosphatase.
The ALDOA Metabolism Pathway as a Potential Target for Regulation of Prostate Cancer Proliferation.
The effect of hormonal therapy of prostatic cancer on serum aldolase.
[Aldolase, acid phosphatase and prostatic phosphatase in the blood of patients with prostatic cancer]
[Importance of aldolase studies in cancer of the prostate]
[Serum aldolase in prostatic cancer]
Protein Deficiency
[Regulatory role of amino acids in protein biosynthesis; effect of various factors]
Proteinuria
Diffuse lymphadenopathy as the presenting manifestation of systemic lupus erythematosus.
Protozoan Infections
Bisphosphonate inhibitors of mammalian glycolytic aldolase.
Psoriasis
EPIDERMAL ALDOLASE LEVELS IN PSORIASIS AND NORMAL SKIN.
[Evaluation of the activities of several erythrocyte enzymes (G6PDH, 6PGDH, PHI, aldolase and LDH) in psoriasis]
Puberty, Delayed
A syndrome of mental retardation, short stature, hemolytic anemia, delayed puberty, and abnormal facial appearance: similarities to a report of aldolase A deficiency.
Pulmonary Edema
Patterns of serum aspartic and alanine aminotransferase as well as aldolase activity in attacks of bronchial asthma, paroxysmal tachycardia and pulmonary edema.
[Pattern of activity of aspartic aminotransferase, alanine aminotransferase and aldolase in attacks of bronchial asthma, paroxysmal tachycardia and pulmonary edema]
Pulmonary Infarction
[Isoenzymes of fructosephosphate aldolase in the serum of rabbits with experimental pulmonary infarction]
Pulmonary Valve Stenosis
Severe acidosis in a neonate with pulmonary valve stenosis: a possible stress inducer of a fatal syndrome of fructose-1, 6-biphosphatase and aldolase deficiency.
Pyelonephritis
[General activity of aldolase and its isoenzymes in pyelonephritis in children]
Pyomyositis
Serum aldolase and urinary taurine excretion in pyomyositis.
Rectal Neoplasms
High Expression of Aldolase B Confers a Poor Prognosis for Rectal Cancer Patients Receiving Neoadjuvant Chemoradiotherapy.
Renal Insufficiency
Integration of PCR-Sequencing Analysis with Multiplex Ligation-Dependent Probe Amplification for Diagnosis of Hereditary Fructose Intolerance.
[Fructosediphosphate and fructosemonophosphate aldolase activity in the kidneys and blood serum in experimental renal insufficiency]
Respiratory Insufficiency
Glycolytic enzymes of human fetal and neonatal intraocular fluids.
Respiratory Tract Infections
[Aldolase and transaminase activity of blood serum in acute respiratory infections in children]
Retinal Diseases
Impact of Autoantibodies against Glycolytic Enzymes on Pathogenicity of Autoimmune Retinopathy and Other Autoimmune Disorders.
Rhabdomyolysis
A thermolabile aldolase A mutant causes fever-induced recurrent rhabdomyolysis without hemolytic anemia.
Acute renal failure due to nontraumatic rhabdomyolysis.
Acute rhabdomyolysis and inflammation.
Aldolase A deficiency: Report of new cases and literature review.
Glycogen storage disease type XII; an ultra rare cause of hemolytic anemia and rhabdomyolysis: one new case report.
Hemolytic anemia and severe rhabdomyolysis caused by compound heterozygous mutations of the gene for erythrocyte/muscle isozyme of aldolase, ALDOA(Arg303X/Cys338Tyr).
Rhabdomyolysis associated with Crohn's disease.
Statin-induced delayed rhabdomyolysis.
Tsutsugamushi infection-associated acute rhabdomyolysis and acute renal failure.
Unraveling the structural and functional features of an aldolase A mutant involved in the hemolytic anemia and severe rhabdomyolysis reported in a child.
[A case of fulminant psittacosis with rhabdomyolysis]
[A case of rhabdomyolysis following long time immobile posture caused by schizophrenia]
[Investigation of etiologies for acute renal failure due to rhabdomyolysis in 5 patients]
Rheumatic Diseases
[Effect of vitamin E on aldolase activity in chronic progressive rheumatism.]
[Fructose-1-phosphate aldolase activity in the blood serum in rheumatism]
[On diagnostic possibility of the "active" phase of rheumatic disease in the light of clinical, biochemical and histopathological studies. Report I. Behavior of aldolase, transaminase and of certain other laboratory and clinical indices in patients subjected to surgical interventions on the bicuspid valve.]
Rheumatic Fever
[Serum aldolase activity in the course of rheumatic fever in children]
Rubella
[Tests of oxygen consumption and of the activity of fructose-1, 6-diphosphate aldolase as well as of fatty acid composition of BHK 21 cells infected with rubella virus]
Sarcoidosis
Sarcoidosis patient with lupus pernio and infliximab-induced myositis: Response to Acthar gel.
Sarcoma
Aldolase-DNA interactions in a SEWA cell system.
Crystallization and properties of aldolase from a transplantable rat sarcoma.
Enzyme changes induced in normal and malignant tissues with chemical agents. IV. Effect of alpha-peltatin on glucose utilization by sarcoma 37 and on the adenosinetriphosphatase, hexokinase, aldolase, and pyridine nucleotide levels of sarcoma 37.
Sarcoma 180
[Anti-cancer activity of Zuojinwan in vivo and influence to tumor markers in mice transplanted with sarcoma 180]
Sarcoma 37
Enzyme changes induced in normal and malignant tissues with chemical agents. IV. Effect of alpha-peltatin on glucose utilization by sarcoma 37 and on the adenosinetriphosphatase, hexokinase, aldolase, and pyridine nucleotide levels of sarcoma 37.
Schistosomiasis
Diagnosis of schistosomiasis using recombinant fructose-1,6-bisphosphate aldolase from a Formosan strain of Schistosoma japonicum.
Evaluation of recombinant SjLAP and SjFBPA in detecting antibodies to Schistosoma japonicum.
Schistosomiasis japonica
Evaluation of recombinant SjLAP and SjFBPA in detecting antibodies to Schistosoma japonicum.
Schistosomiasis mansoni
Protective and anti-pathology effects of Sm fructose-1,6-bisphosphate aldolase-based DNA vaccine against schistosoma mansoni by changing route of injection.
Scleroderma, Systemic
Aldolase predicts subsequent myopathy occurrence in systemic sclerosis.
Seizures
[Activity of aldolase, lactate dehydrogenase and content of lactic and pyroracemic acids in different areas of the brain in rat, with repeated convulsions evoked by corazole]
Severe Dengue
Differential expression of aldolase, alpha tubulin and thioredoxin peroxidase in peripheral blood mononuclear cells from dengue fever and dengue hemorrhagic fever patients.
Sexually Transmitted Diseases
Dermatomyositis with panniculitis.
Skin Diseases
von Willebrand factor in juvenile dermatomyositis.
[Aldolase activity in blood & blister fluid in dermatoses.]
Sleep Initiation and Maintenance Disorders
[Change in the activity of glycolytic enzymes in different areas of the albino rat brain in dependence on the stress agent]
Squamous Cell Carcinoma of Head and Neck
Suppression of fructose-bisphosphate aldolase C expression as a predictor of advanced oral squamous cell carcinoma.
Starvation
Dietary regulation of aldolase isozyme expression in rat intestinal mucosa.
Membrane markers of endoplasmic reticulum preserved in autophagic vacuolar membranes isolated from leupeptin-administered rat liver.
Modification of rat liver fructose biphosphate aldolase by lysosomal proteinases.
Saccharomyces cerevisiae aldolase mutants.
Similarities in properties, content, and relative rates of synthesis of fructose-P2 aldolase in livers of fed and starved rats.
Starvation-induced lysosomal degradation of aldolase B requires glutamine 111 in a signal sequence for chaperone-mediated transport.
The effect of pyridoxal phosphate on the activity of aldolase from Lemna minor L.
The response of Cupriavidus metallidurans CH34 to spaceflight in the international space station.
Ubiquitinated aldolase B accumulates during starvation-induced lysosomal proteolysis.
[Conformational changes in rabbit muscle aldolase under normal conditions and following prolonged starvation]
[Effects of starvation, a hyperprotein diet and treatment with nicotinamide on L-threonine aldolase and allothreonine aldolase in the rat liver]
[On the correlation fo fructosediphosphate and fructosemonophosphate aldolase activities in rat tissues under toxic conditions and starvation]
Still's Disease, Adult-Onset
Serum aldolase serves as a useful marker for diagnosis and assessment of disease activity in patients with adult-onset Still's disease.
Stillbirth
Glycolytic enzymes of human fetal and neonatal intraocular fluids.
Stomach Neoplasms
Aldolase A as a prognostic factor and mediator of progression via inducing epithelial-mesenchymal transition in gastric cancer.
Alteration of aldolase isozymes in serum and tissues of patients with cancer and other diseases.
Comparative proteomics analysis of gastric cancer stem cells.
Downregulation of ALDOB is associated with poor prognosis of patients with gastric cancer.
[Changes in serum phosphohexosisomerase and aldolase activity in stomach cancer patients]
[Studies on aldolase isozymes in gastric cancer]
Stomach Volvulus
Delayed diagnosis of intermittent mesenteroaxial volvulus of the stomach by computed tomography: a case report.
Stroke
Activity of creatine kinase, aminotransferases and aldolase in cerebral strokes.
Aldolase C/zebrin II is released to the extracellular space after stroke and inhibits the network activity of cortical neurons.
[Behavior of aldolase and lactic dehydrogenase activity of the cerebrospinal fluid in cerebral apoplexy.]
Subarachnoid Hemorrhage
Intranasal wnt-3a alleviates neuronal apoptosis in early brain injury post subarachnoid hemorrhage via the regulation of wnt target PPAN mediated by the moonlighting role of aldolase C.
Synovitis
[Elevated serum aldolase activity in a patient of non-eosinophilic myofasciitis and synovitis with perifascicular atrophy]
Tachycardia, Paroxysmal
Patterns of serum aspartic and alanine aminotransferase as well as aldolase activity in attacks of bronchial asthma, paroxysmal tachycardia and pulmonary edema.
[Pattern of activity of aspartic aminotransferase, alanine aminotransferase and aldolase in attacks of bronchial asthma, paroxysmal tachycardia and pulmonary edema]
Tay-Sachs Disease
FRUCTOSE-1 PHOSPHATE ALDOLASE DEFICIENCY IN TAY-SACHS DISEASE.
Serum aldolase in Tay-Sachs disease and in fructose intolerance.
Testicular Neoplasms
The aldolase and pyruvate kinase isoenzyme patterns in a malignant testicular tumor from a 27 year old male.
Tetanus
Importance of serum aldolase estimation in cases of tetanus.
Serum aldolase in tetanus.
[Behavior of serum aldolase in experimental tetanus in guinea pigs.]
[Research on the behavior of serum aldolase in experimental tetanus poisoning.]
[Study of the serum Levels of creatine phosphokinase and aldolase in patients with tetanus]
Thalassemia
Distortion of the ?-globin Chain of Hemoglobin Alters the Pathway of Erythrocytic Glucose Metabolism Through Band 3 Protein.
[Aldolase activity of erythrocytes in thalassemia and thalassodrepanocytosis.]
[VARIATIONS IN THE BLOOD LEVEL OF ALDOLASE IN THALASSEMIA PATIENTS AFTER TRANSFUSION.]
Thiamine Deficiency
HIF1-?-mediated gene expression induced by vitamin B1 deficiency.
Thrombocytosis
Tryptophan-induced eosinophilia-myalgia syndrome.
Thrombosis
Statin-induced delayed rhabdomyolysis.
Variations in platelet protein associated with arterial thrombosis.
Trichinellosis
Elevation of serum aldolase and transaminases level in the course of trichinellosis.
[Aldolase reaction to fructose-1,6-phosphate and fructose-1-phosphate in patients with trichinosis and viral hepatitis]
[Behavior of serum aldolase and transaminase activity in trichinosis; preliminary communication.]
Trypanosomiasis, African
Genetic validation of aldolase and glyceraldehyde-3-phosphate dehydrogenase as drug targets in Trypanosoma brucei.
Structure- and Ligand-Based Structure-Activity Relationships for a Series of Inhibitors of Aldolase.
Structure-Based Virtual Screening and Biochemical Evaluation for the Identification of Novel Trypanosoma brucei Aldolase Inhibitors.
Structures of type 2 peroxisomal targeting signals in two trypanosomatid aldolases.
Tuberculosis
A noncompetitive inhibitor for Mycobacterium tuberculosis's class IIa fructose 1,6-bisphosphate aldolase.
Active site loop dynamics of a class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis.
Characterization of a Mycobacterium tuberculosis nanocompartment and its potential cargo proteins.
Characterization of an Aldolase Involved in Cholesterol Side Chain Degradation in Mycobacterium tuberculosis.
Characterization of an Aldolase-Dehydrogenase Complex from the Cholesterol Degradation Pathway of Mycobacterium tuberculosis.
Cheminformatics based machine learning approaches for assessing glycolytic pathway antagonists of Mycobacterium tuberculosis.
Development of metal-chelating inhibitors for the Class II fructose 1,6-bisphosphate (FBP) aldolase.
Evaluation of four microbial Class II fructose 1,6-bisphosphate aldolase enzymes for use as biocatalysts.
Fructose-1,6-diphosphate aldolase of Mycobacterium tuberculosis H37Rv.
Glycolytic and non-glycolytic functions of Mycobacterium tuberculosis fructose-1,6-bisphosphate aldolase, an essential enzyme produced by replicating and non-replicating bacilli.
In silico study of 4-phosphorylated derivatives of 1,3-oxazole as inhibitors of Candida albicans fructose-1,6-bisphosphate aldolase II.
Inactivation of fructose-1,6-bisphosphate aldolase prevents optimal co-catabolism of glycolytic and gluconeogenic carbon substrates in Mycobacterium tuberculosis.
Molecular cloning, expression, purification, and characterization of fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis--a novel Class II A tetramer.
Structural basis for catalysis of a tetrameric class IIa fructose 1,6-bisphosphate aldolase from Mycobacterium tuberculosis.
The steroid side-chain-cleaving aldolase Ltp2-ChsH2DUF35 is a thiolase superfamily member with a radically repurposed active site.
[ALDOLASE ACTIVITY OF THE BLOOD OF PATIENTS WITH OSSEOUS TUBERCULOSIS.]
[Blood serum aldolase activity in children and adolescents with tuberculosis]
[Significance of the aldolase test in evaluation of liver parenchyma lesions in tuberculosis with relation to serum lability tests and protein determination.]
Tuberculosis, Meningeal
[Aldolase activity of the cerebrospinal fluid in tuberculous meningitis]
[BEHAVIOR OF THE ALDOLASE LEVEL IN THE BLOOD SERUM AND CEREBROSPINAL FLUID IN CHILDREN WITH TUBERCULOUS MENINGITIS.]
Tuberculosis, Pulmonary
[Activity of serum aldolase and transaminase in patients with chronic destructive forms of pulmonary tuberculosis during treatment with prothionamide]
[ALDOLASE ACTIVITY OF THE SERUM IN PULMONARY TUBERCULOSIS.]
[Research on the diagnostic value of the blood aldolase activity in pulmonary tuberculosis.]
[Serum aldolase in children and adolescents with pulmonary tuberculosis]
[SERUM VALUES OF ALDOLASE IN PULMONARY TUBERCULOSIS OF CHILDHOOD.]
Tuberous Sclerosis
Malignant pleural effusion cells show aberrant glucose metabolism gene expression.
Urinary Bladder Neoplasms
ALDOLASE A regulates invasion of bladder cancer cells via E-cadherin-EGFR signaling.
[A study on aldolase activity and isozyme pattern of the bladder tumor (author's transl)]
Urogenital Neoplasms
[Urogenital cancer and aldolase]
Urologic Diseases
Elevated levels of serum aldolase A in patients with renal cell carcinoma.
Use of serum gamma-enolase and aldolase A in combination as markers for renal cell carcinoma.
Uterine Cervical Neoplasms
Aldolase A promotes epithelial-mesenchymal transition to increase malignant potentials of cervical adenocarcinoma.
Recombinant Viral Capsid Protein L2 (rVL2) of HPV 16 Suppresses Cell Proliferation and Glucose Metabolism via ITGB7/C/EBP? Signaling Pathway in Cervical Cancer Cell Lines.
Uterine Neoplasms
Significance of serum tumor markers in patients with carcinoma of the ovary.
[Changes in serum aldolase caused by hormone therapy of uterine cancer patients.]
[Plasma aldolase activity in radium therapy of cancer of the uterus.]
Vaccinia
Pathology of carbohydrate metabolism in virus-infected cell cultures. I. Alterations of aldolase activity in cultures infected with vaccinia and mumps viruses.
Viremia
Genetic variations in humans associated with differences in the course of hepatitis C.
Virus Diseases
Dynamics of the Interaction between Cotton Bollworm Helicoverpa armigera and Nucleopolyhedrovirus as Revealed by Integrated Transcriptomic and Proteomic Analyses.
Identification of four isoforms of aldolase B down-regulated in hepatocellular carcinoma tissues by means of two-dimensional Western blotting.
[Use of aldolase reaction in chick embryo in virus disease diagnosis; preliminary communication.]
Vitamin E Deficiency
Alterations in tissue and serum aldolase in rabbits due to vitamin E deficiency.
Wiskott-Aldrich Syndrome
A hydrophobic pocket in the active site of glycolytic aldolase mediates interactions with Wiskott-Aldrich syndrome protein.
Actin filament- and Wiskott-Aldrich syndrome protein-binding sites on fructose-1,6-bisphosphate aldolase are functionally distinct from the active site.
Aldolase sequesters WASP and affects WASP/Arp2/3-stimulated actin dynamics.
Characterization of an aldolase-binding site in the Wiskott-Aldrich syndrome protein.
Zika Virus Infection
Analysis of cellular proteome changes in response to ZIKV NS2B-NS3 protease expression.