Disease on EC 4.1.1.65 - phosphatidylserine decarboxylase
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Candidiasis
Candida albicans cannot acquire sufficient ethanolamine from the host to support virulence in the absence of de novo phosphatidylethanolamine synthesis.
Cataract
PISD is a mitochondrial disease gene causing skeletal dysplasia, cataracts, and white matter changes.
Hyperalgesia
Nerve injury-induced tactile allodynia is present in the absence of FOS labeling in retrogradely labeled post-synaptic dorsal column neurons.
Hyperalgesia
Sensitization of postsynaptic dorsal column neuronal responses by colon inflammation.
Hyperalgesia
Spinal Cord Stimulation Modulates Visceral Nociception and Hyperalgesia via the Spinothalamic Tracts and the Postsynaptic Dorsal Column Pathways: A Literature Review and Hypothesis.
Infections
Candida albicans cannot acquire sufficient ethanolamine from the host to support virulence in the absence of de novo phosphatidylethanolamine synthesis.
Neoplasms
NK-1-receptor-mediated lesion of spinal post-synaptic dorsal column neurons might improve intractable visceral pain of cancer origin.
Neuralgia
Spinal Cord Stimulation Modulates Visceral Nociception and Hyperalgesia via the Spinothalamic Tracts and the Postsynaptic Dorsal Column Pathways: A Literature Review and Hypothesis.
Neuroinflammatory Diseases
Evaluation of an alpha synuclein sensitized dendritic cell based vaccine in a transgenic mouse model of Parkinson's disease.
Parkinson Disease
Lipid disequilibrium in biological membranes, a possible pathway to neurodegeneration.
Retinal Degeneration
Autophagy-dependent rhodopsin degradation prevents retinal degeneration in Drosophila.
Starvation
The mitochondrial phosphatidylserine decarboxylase Psd1 is involved in nitrogen starvation-induced mitophagy in yeast.
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