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Information on EC 3.7.1.14 - 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase

for references in articles please use BRENDA:EC3.7.1.14
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IUBMB Comments
This enzyme catalyses a step in a pathway of phenylpropanoid compounds degradation. The first step of the enzyme mechanism involves a reversible keto-enol tautomerization .
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The expected taxonomic range for this enzyme is: Escherichia coli
Synonyms
2-hydroxy-6-keto-nona-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-ketonona-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase, 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase, MCP hydrolase, meta-cleavage product hydrolase, MhpC, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(2Z,4E)-2-hydroxy-6-oxonona-2,4-diene-1,9-dioate + H2O = (2Z)-2-hydroxypenta-2,4-dienoate + succinate
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(2Z,4E,7E)-2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioate + H2O = (2Z)-2-hydroxypenta-2,4-dienoate + fumarate
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