show all | hide all No of entries

Information on EC 3.7.1.12 - cobalt-precorrin 5A hydrolase

for references in articles please use BRENDA:EC3.7.1.12
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
EC Tree
     3 Hydrolases
         3.7 Acting on carbon-carbon bonds
             3.7.1 In ketonic substances
                3.7.1.12 cobalt-precorrin 5A hydrolase
IUBMB Comments
This enzyme hydrolyses the ring A acetate delta-lactone of cobalt-precorrin-5A resulting in the loss of the C-20 carbon and its attached methyl group in the form of acetaldehyde. This is a key reaction in the contraction of the porphyrin-type tetrapyrrole ring and its conversion to a corrin ring in the anaerobic (early cobalt insertion) adenosylcobalamin biosynthesis pathway.
Specify your search results
Select one or more organisms in this record:
The enzyme appears in viruses and cellular organisms
Synonyms
CbiG, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
cobalt-precorrin-5A + H2O = cobalt-precorrin-5B + acetaldehyde + 2 H+
show the reaction diagram
-
-
-
-
Select items on the left to see more content.