Reference on EC 3.6.5.6 - tubulin GTPase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Monasterio, O.; Timasheff, S.N.
Inhibition of tubulin self-assembly and tubulin-colchicine GTPase activity by guanosine 5'-(gamma-fluorotriphosphate)
Biochemistry
26
6091-6099
1987
Bos taurus
Caplow, M.; Shanks, J.
Mechanism of the microtubule GTPase reaction
J. Biol. Chem.
265
8935-8941
1990
Bos taurus, Sus scrofa
Burns, R.G.
Kinetics of GTP hydrolysis during the assembly of chick brain MAP-tubulin microtubule protein
Biochem. J.
277
239-243
1991
Gallus gallus
Roychowdhury, S.; Rasenick, M.M.
Tubulin-G protein association stabilizes GTP binding and activates GTPase: Cytoskeletal participation in neuronal signal transduction
Biochemistry
33
9800-9805
1994
Bos taurus, Gallus gallus
Perez-Ramirez, B.; Shearwin, K.E.; Timasheff, S.N.
The colchicine-induced GTPase activity of tubulin: State of the product. Activation by microtubule-promoting cosolvents
Biochemistry
33
6253-6261
1994
Bos taurus
Perez-Ramirez, B.; Timasheff, S.N.
Cosolvent modulation of the tubulin-colchicine GTPase-activating conformational change: Strength of the enzymatic activity
Biochemistry
33
6262-6267
1994
Bos taurus
Sage, C.R.; Dougherty, C.A.; Davis, A.S.; Burns, R.G.; Wilson, L.; Farrell, K.W.
Site directed mutagenesis of putative GTP-binding sites of yeast beta-tubulin: Evidence that alpha-, beta-, and gamma-tubulins are atypical GTPases
Biochemistry
34
7409-7419
1995
Bos taurus, Saccharomyces cerevisiae, Gallus gallus
Mejillano, M.R.; Shivanna, B.D.; Himes, R.H.
Studies on the nocodazole-induced GTPase activity of tubulin
Arch. Biochem. Biophys.
336
130-138
1996
Bos taurus
Soto, C.; Rodriguez, P.H.; Monasterio, O.
Calcium and gadolinium ions stimulate the GTPase activity of purified chicken brain tubulin through a conformational change
Biochemistry
35
6337-6344
1996
Gallus gallus
Best, A.; Ahmed, S.; Kozma, R.; Lim, L.
The ras-related GTPase Rac1 binds tubulin
J. Biol. Chem.
271
3756-3762
1996
Rattus norvegicus
Banerjee, A.
Differential effects of colchicine and its B-ring modified analog MTPT on the assembly-independent GTPase activity of purified beta-tubulin isoforms from bovine brain
Biochem. Biophys. Res. Commun.
231
698-700
1997
Bos taurus
Tian, G.; Bhamidipati, A.; Cowan, N.J.; Lewis, S.A.
Tubulin folding cofactors as GTPase-activating proteins
J. Biol. Chem.
274
24054-24058
1999
Bos taurus, Gallus gallus, Mus musculus
Roychowdhury, S.; Panda, D.; Wilson, L.; Rasenick, M.M.
G Protein alpha subunits activate tubulin GTPase and modulate microtubule polymerization dynamics
J. Biol. Chem.
274
13485-13490
1999
Bos taurus, Ovis aries
Dougherty, C.A.; Sage, C.R.; Davis, A.; Farrell, K.W.
Mutation in the beta-tubulin signature motif suppresses microtubule GTPase activity and dynamics, and slows mitosis
Biochemistry
40
15725-15732
2001
Saccharomyces cerevisiae
Gupta, K.; Panda, D.
Perturbation of microtubule polymerization by quercetin through tubulin binding: a novel mechanism of its antiproliferative activity
Biochemistry
41
13029-13038
2002
Capra hircus
Brannstrom, K.; Segerman, B.; Gullberg, M.
Molecular dissection of GTP exchange and hydrolysis within the ternary complex of tubulin heterodimers and Op18/stathmin family members
J. Biol. Chem.
278
16651-16657
2003
Homo sapiens
Anders, K.R.; Botstein, D.
Dominant-lethal alpha-tubulin mutants defective in microtubule depolymerization in yeast
Mol. Biol. Cell
12
3973-3986
2001
Saccharomyces cerevisiae
Buey, R.M.; Diaz, J.F.; Andreu, J.M.
The nucleotide switch of tubulin and microtubule assembly: a polymerization-driven structural change
Biochemistry
45
5933-5938
2006
Bos taurus, Rattus norvegicus
Nogales, E.; Wang, H.W.
Structural mechanisms underlying nucleotide-dependent self-assembly of tubulin and its relatives
Curr. Opin. Struct. Biol.
16
221-229
2006
Prosthecobacter sp.
Sontag, C.A.; Staley, J.T.; Erickson, H.P.
In vitro assembly and GTP hydrolysis by bacterial tubulins BtubA and BtubB
J. Cell Biol.
169
233-238
2005
Prosthecobacter sp.
Banerjee, M.; Poddar, A.; Mitra, G.; Surolia, A.; Owa, T.; Bhattacharyya, B.
Sulfonamide drugs binding to the colchicine site of tubulin: thermodynamic analysis of the drug-tubulin interactions by isothermal titration calorimetry
J. Med. Chem.
48
547-555
2005
Capra hircus
Wang, C.; Cormier, A.; Gigant, B.; Knossow, M.
Insight into the GTPase activity of tubulin from complexes with stathmin-like domains
Biochemistry
46
10595-10602
2007
Bos taurus
Layden, B.T.; Saengsawang, W.; Donati, R.J.; Yang, S.; Mulhearn, D.C.; Johnson, M.E.; Rasenick, M.M.
Structural model of a complex between the heterotrimeric G protein, Gsalpha, and tubulin
Biochim. Biophys. Acta
1783
964-973
2008
Ovis aries
Xi, J.H.; Bai, F.; McGaha, R.; Andley, U.P.
Alpha-crystallin expression affects microtubule assembly and prevents their aggregation
FASEB J.
20
846-857
2006
Bos taurus, Mus musculus
Gupta, K.K.; Bharne, S.S.; Rathinasamy, K.; Naik, N.R.; Panda, D.
Dietary antioxidant curcumin inhibits microtubule assembly through tubulin binding
FEBS J.
273
5320-5332
2006
Capra hircus
Srivastava, P.; Panda, D.
Rotenone inhibits mammalian cell proliferation by inhibiting microtubule assembly through tubulin binding
FEBS J.
274
4788-4801
2007
Capra hircus
Tang, M.; Bideshi, D.K.; Park, H.W.; Federici, B.A.
Iteron-binding ORF157 and FtsZ-like ORF156 proteins encoded by pBtoxis play a role in its replication in Bacillus thuringiensis subsp. israelensis
J. Bacteriol.
189
8053-8058
2007
Bacillus thuringiensis
Thakur, M.; Chakraborti, P.K.
GTPase activity of mycobacterial FtsZ is impaired due to its transphosphorylation by the eukaryotic-type Ser/Thr kinase, PknA
J. Biol. Chem.
281
40107-40113
2006
Escherichia coli, Mycobacterium tuberculosis
Inoue, I.; Ino, R.; Nishimura, A.
New model for assembly dynamics of bacterial tubulin in relation to the stages of DNA replication
Genes Cells
14
435-444
2009
Escherichia coli
Cormier, A.; Clement, M.J.; Knossow, M.; Lachkar, S.; Savarin, P.; Toma, F.; Sobel, A.; Gigant, B.; Curmi, P.A.
The PN2-3 domain of centrosomal P4.1-associated protein implements a novel mechanism for tubulin sequestration
J. Biol. Chem.
284
6909-6917
2009
Ovis aries
Mendieta, J.; Rico, A.I.; Lopez-Vinas, E.; Vicente, M.; Mingorance, J.; Gomez-Puertas, P.
Structural and functional model for ionic (K(+)/Na(+)) and pH dependence of GTPase activity and polymerization of FtsZ, the prokaryotic ortholog of tubulin
J. Mol. Biol.
390
17-25
2009
Methanocaldococcus jannaschii (Q57816), Methanocaldococcus jannaschii
Nakajima, K.; Niisato, N.; Marunaka, Y.
Enhancement of tubulin polymerization by Cl--induced blockade of intrinsic GTPase
Biochem. Biophys. Res. Commun.
425
225-229
2012
Sus scrofa
Geyer, E.A.; Burns, A.; Lalonde, B.A.; Ye, X.; Piedra, F.A.; Huffaker, T.C.; Rice, L.M.
A mutation uncouples the tubulin conformational and GTPase cycles, revealing allosteric control of microtubule dynamics
eLife
4
e10113
2015
Saccharomyces cerevisiae
Modi, K.M.; Tewari, R.; Misra, H.S.
FtsZDr, a tubulin homologue in radioresistant bacterium Deinococcus radiodurans is characterized as a GTPase exhibiting polymerization/depolymerization dynamics in vitro and FtsZ ring formation in vivo
Int. J. Biochem. Cell Biol.
50
38-46
2014
Deinococcus radiodurans (Q9RWN5), Deinococcus radiodurans
Bailey, M.E.; Jiang, N.; Dima, R.I.; Ross, J.L.
Microtubule severing enzymes couple ATPase activity with tubulin GTPase spring loading
Biopolymers
105
547-556
2016
Homo sapiens (P23258)
Lindstroem, L.; Li, T.; Malycheva, D.; Kancharla, A.; Nilsson, H.; Vishnu, N.; Mulder, H.; Johansson, M.; Rossello, C.A.; Alvarado-Kristensson, M.
The GTPase domain of gamma-tubulin is required for normal mitochondrial function and spatial organization
Commun. Biol.
1
37
2018
Homo sapiens (P23258)
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