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Information on EC 3.6.1.61 - diadenosine hexaphosphate hydrolase (ATP-forming)

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IUBMB Comments
The enzyme requires the presence of the divalent cations (Mn2+, Mg2+, Zn2+, and Co2+). It hydrolyses P1,P4-bis(5-guanosyl) tetraphosphate very slowly [cf. EC 3.6.1.17, bis(5-nucleosyl)-tetraphosphatase (asymmetrical)].
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The enzyme appears in viruses and cellular organisms
Synonyms
Ndx1, ygdP, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
P1,P4-bis(5'-adenosyl)tetraphosphate + H2O = ATP + AMP
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P1,P5-bis(5'-adenosyl)pentaphosphate + H2O = ATP + ADP
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P1,P6-bis(5'-adenosyl)hexaphosphate + H2O = 2 ATP
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PATHWAY SOURCE
PATHWAYS
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