Disease on EC 3.6.1.29 - bis(5'-adenosyl)-triphosphatase
Please use the Disease Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Adenocarcinoma
Abnormal fragile histidine triad (Fhit) expression in invasive cervical adenocarcinoma: association with tumor aggressiveness.
Adenocarcinoma
Altered expression of the fragile histidine triad gene in primary gastric adenocarcinomas.
Adenocarcinoma
Clinicopathological significance of FHIT protein expression in gastric adenocarcinoma patients.
Adenocarcinoma
Correlation of aberrant expression of CD133 with FHIT and malignant phenotype of colorectal adenocarcinoma.
Adenocarcinoma
FHIT alterations in lung adenocarcinomas induced by N-nitrosobis(2-hydroxypropyl)amine in rats.
Adenocarcinoma
Fhit expression in gastric adenocarcinoma: correlation with disease stage and survival.
Adenocarcinoma
FHIT protein expression and its relation to apoptosis, tumor histologic grade and prognosis in colorectal adenocarcinoma: an immunohistochemical and image analysis study.
Adenocarcinoma
Fhit protein expression in lung cancer studied by high-throughput tissue microarray.
Adenocarcinoma
FHIT protein is expressed in benign mesothelium and has no clinical value in detecting carcinoma in body cavity effusions.
Adenocarcinoma
Immunohistochemical expression of FHIT gene product in inflammatory bowel disease: significance and correlation with clinicopathological data.
Adenocarcinoma
Immunohistochemical expression of Fhit protein in Helicobacter pylori related chronic gastritis, gastric precancerous lesions and gastric carcinoma: correlation with conventional clinicopathologic parameters.
Adenocarcinoma
Loss of fragile histidine triad and amplification of 1p36.22 and 11p15.5 in primary gastric adenocarcinomas.
Adenocarcinoma
Promoter hypermethylation of p16INK4a, E-cadherin, O6-MGMT, DAPK and FHIT in adenocarcinomas of the esophagus, esophagogastric junction and proximal stomach.
Adenocarcinoma
[Relationship between hMSH2 and FHIT gene expression in non-small cell lung cancer]
Adenoma
Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types.
Adenoma
Decreased fragile histidine triad expression in colorectal cancer and its association with apoptosis inhibition.
Adenoma
Frequent altered expression of fragile histidine triad protein in human colorectal adenomas.
Adenoma
Prevalence and distinctive biologic features of flat colorectal adenomas in a North American population.
Adenoma
[Abnormal expression of fragile histidine triad (FHIT) and Mut S homolog 2 (MSH2) proteins in human sporadic colorectal carcinoma and their clinical significance]
Adenomatous Polyposis Coli
DNA hypermethylation profiles in squamous cell carcinoma of the vulva.
Adenomatous Polyposis Coli
Hypermethylation of FHIT as a prognostic marker in nonsmall cell lung carcinoma.
Adenomatous Polyposis Coli
Usefulness of plasma epigenetic changes of five major genes involved in the pathogenesis of colorectal cancer.
Adenomatous Polyposis Coli
[Aberrant promoter methylation of tumor suppressor genes in serum from lung cancer patients: frequency and correlation with clinicopathological characteristics]
Ameloblastoma
Assessment of fragile histidine triad expression in ameloblastoma, odontogenic keratocyst and dentigerous cyst.
Bowen's Disease
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Breast Neoplasms
Alterations of the FHIT gene in breast cancer: association with tumor progression and patient survival.
Breast Neoplasms
Analysis of FHIT Gene Methylation in Egyptian Breast Cancer Women: Association with Clinicopathological Features.
Breast Neoplasms
Analysis of the fragile histidine triad (FHIT) gene in lobular breast cancer.
Breast Neoplasms
Clinicopathological significance of fragile histidine triad transcription protein expression in breast carcinoma.
Breast Neoplasms
Comparative analysis of loss of heterozygosity of specific chromosome 3, 13, 17, and X loci and TP53 mutations in human epithelial ovarian cancer.
Breast Neoplasms
Correlations of breast cancer FHIT gene with the incidence and prognosis of breast cancer.
Breast Neoplasms
Expression characteristics of FHIT, p53, BRCA2 and MLH1 in families with a history of oesophageal cancer in a region with a high incidence of oesophageal cancer.
Breast Neoplasms
Fhit expression protects against HER2-driven breast tumor development: unraveling the molecular interconnections.
Breast Neoplasms
FHIT loss of function in human primary breast cancer correlates with advanced stage of the disease.
Breast Neoplasms
Fragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in breast cancer.
Breast Neoplasms
Loss of FHIT expression in breast cancer is correlated with poor prognostic markers.
Breast Neoplasms
Loss of FHIT protein expression is a marker of adverse evolution in good prognosis localized breast cancer.
Breast Neoplasms
Loss of heterozygosity on chromosomes 3, 9, 13, and 17, including the retinoblastoma locus, in uveal melanoma.
Breast Neoplasms
Mutational and promoter hypermethylation status of FHIT gene in breast cancer patients of Kashmir.
Breast Neoplasms
Promoter methylation status of the FHIT gene and Fhit expression: Association with HER2/neu status in breast cancer patients.
Breast Neoplasms
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in breast cancer cell lines.
Breast Neoplasms
The expression of Fhit protein is related inversely to disease progression in patients with breast carcinoma.
Breast Neoplasms
[Loss of fragile histidine triad expression and metastasis in breast cancer]
Burkitt Lymphoma
Frequent silencing of fragile histidine triad gene (FHIT) in Burkitt's lymphoma is associated with aberrant hypermethylation.
Carcinogenesis
A knockdown with smoke model reveals FHIT as a repressor of Heme oxygenase 1.
Carcinogenesis
Abnormal Fhit protein expression and high frequency of microsatellite instability in sporadic colorectal cancer.
Carcinogenesis
Absence of FHIT expression is associated with apoptosis inhibition in colorectal cancer.
Carcinogenesis
Absence of Fhit protein in primary lung tumors and cell lines with FHIT gene abnormalities.
Carcinogenesis
Alteration of the fragile histidine triad gene early in carcinogenesis: an update.
Carcinogenesis
Alterations of the fragile histidine triad gene, FHIT, and its encoded products contribute to testicular germ cell tumorigenesis.
Carcinogenesis
Altered expression of the fragile histidine triad gene in primary gastric adenocarcinomas.
Carcinogenesis
Altered p16INK4a and Fhit expression in carcinogenesis and progression of human oral cancer.
Carcinogenesis
Analysis of FHIT allelic imbalance/loss of heterozygosity and FHIT expression in cutaneous squamous cell carcinomas.
Carcinogenesis
Analysis of the fragile histidine triad (FHIT) gene in lobular breast cancer.
Carcinogenesis
Clinicopathological significance of FHIT protein expression in gastric adenocarcinoma patients.
Carcinogenesis
Clinicopathological significance of the fragile histidine triad transcription protein expression in laryngeal carcinogenesis.
Carcinogenesis
Cytogenetic studies of 24 renal epithelial tumors with von Hippel-Lindau and fragile histidine triad protein expression correlation.
Carcinogenesis
Down-regulation of FHIT inhibits apoptosis of colorectal cancer: mechanism and clinical implication.
Carcinogenesis
Expression of FHIT in esophageal epithelium and carcinoma: reference to drinking, smoking and multicentric carcinogenesis.
Carcinogenesis
Expression of selected miRNA, RAR? and FHIT genes in BALf of squamous cell lung cancer (squamous-cell carcinoma, SCC) patients: a pilot study.
Carcinogenesis
Expression of the fragile histidine triad gene in normal rat tissues and human kidney cancer cell lines.
Carcinogenesis
Fhit expression in human gastric adenomas and intramucosal carcinomas: correlation with Mlh1 expression and gastric phenotype.
Carcinogenesis
FHIT Gene Sequence Variants and Reduced Fhit Protein Expression in Glioblastoma Multiforme.
Carcinogenesis
Fragile histidine triad protein expression in nonsmall cell lung cancer and correlation with Ki-67 and with p53.
Carcinogenesis
Immunohistochemical evaluation of Fhit protein expression in oral squamous cell carcinomas.
Carcinogenesis
Inverse correlation of aberrant expression of fragile histidine triad (FHIT) protein with cyclin D1 protein and prognosis in Chinese patients with cholangiocarcinoma.
Carcinogenesis
Loss of FHIT expression in breast cancer is correlated with poor prognostic markers.
Carcinogenesis
Loss of FHIT expression in squamous cell carcinoma and premalignant lesions of the larynx.
Carcinogenesis
Loss of fragile histidine triad expression in colorectal carcinomas and premalignant lesions.
Carcinogenesis
Loss of fragile histidine triad protein expression in inflammatory bowel disease.
Carcinogenesis
MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family.
Carcinogenesis
Mutation and abnormal expression of the fragile histidine triad gene in nasopharyngeal carcinoma.
Carcinogenesis
Nicotine induces the fragile histidine triad methylation in human esophageal squamous epithelial cells.
Carcinogenesis
Novel missense mutation in FHIT gene: interpreting the effect in HPV-mediated cervical cancer in Indian women.
Carcinogenesis
Prevention of urinary bladder cancer in the FHIT knock-out mouse with Rofecoxib, a Cox-2 inhibitor.
Carcinogenesis
Primary cervical carcinomas show 2 common regions of deletion at 3P, 1 within the FHIT gene: evaluation of allelic imbalance at FHIT, RB1 and TP53 in relation to survival.
Carcinogenesis
Reduced Fhit expression occurs in the early stage of esophageal tumorigenesis: no correlation with p53 expression and apoptosis.
Carcinogenesis
Relationship between abnormality of FHIT gene and EBV infection in gastric cancer.
Carcinogenesis
Restored expression of fragile histidine triad protein and tumorigenicity of cervical carcinoma cells.
Carcinogenesis
Two hydrolase resistant analogues of diadenosine 5',5"'-P1,P3-triphosphate for studies with Fhit, the human fragile histidine triad protein.
Carcinogenesis
[Alteration of FHIT gene and p16 gene in malignant transformed cells induced by crystalline nickel sulfide]
Carcinogenesis
[Correlation between methylation of 5'-CpG islands and inactivation of FHIT gene in cervical cancer.]
Carcinogenesis
[Effects of Methylation of FHIT Gene on it's Protein and mRNA Expression in Non-small Cell Lung Cancer.]
Carcinogenesis
[Expression of FHIT and MDM2 in oral submucous fibrosis and canceration tissues]
Carcinogenesis
[HPV detection and FHIT expression in esophageal squamous carcinoma from high incidence area in Cixian County]
Carcinogenesis
[Interaction between fragile histidine triad methylation, protein expression and human papillomavirus 16 infection in cervical carcinogenesis].
Carcinogenesis
[The biological significance of FHIT protein expression in lung cancer and precancerous tissues detected by tissue microarray.]
Carcinoid Tumor
Molecular alterations to human chromosome 3p loci in neuroendocrine lung tumors.
Carcinoma
5'-CpG island methylation of the FHIT gene is associated with reduced protein expression and higher clinical stage in cervical carcinomas.
Carcinoma
Aberrant methylation of Fragile Histidine Triad gene is associated with poor prognosis in early stage esophageal squamous cell carcinoma.
Carcinoma
Abnormal fragile histidine triad (FHIT) expression in advanced cervical carcinoma: a poor prognostic factor.
Carcinoma
Absence of Fhit protein in primary lung tumors and cell lines with FHIT gene abnormalities.
Carcinoma
Absence of Msh2 protein expression is associated with alteration in the FHIT locus and Fhit protein expression in colorectal carcinoma.
Carcinoma
Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma.
Carcinoma
Altered expression of the fragile histidine triad gene in primary gastric adenocarcinomas.
Carcinoma
Altered p16INK4a and Fhit expression in carcinogenesis and progression of human oral cancer.
Carcinoma
Analysis of FHIT allelic imbalance/loss of heterozygosity and FHIT expression in cutaneous squamous cell carcinomas.
Carcinoma
Analysis of the fragile histidine triad gene in primary gastric carcinomas and gastric carcinoma cell lines.
Carcinoma
Assessment of the prognostic value of methylation status and expression levels of FHIT, GSTP1 and p16 in non-small cell lung cancer in Egyptian patients.
Carcinoma
Association between germline variation in the FHIT gene and prostate cancer in Caucasians and African Americans.
Carcinoma
Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types.
Carcinoma
Clinicopathological significance of FHIT protein expression in gastric adenocarcinoma patients.
Carcinoma
Clinicopathological significance of Fhit protein expression in stage I non-small cell lung carcinoma.
Carcinoma
Clinicopathological significance of the fragile histidine triad transcription protein expression in laryngeal carcinogenesis.
Carcinoma
Decreased fragile histidine triad gene protein expression is associated with worse prognosis in oral squamous carcinoma.
Carcinoma
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Carcinoma
Deletions of BRCA1/2 and p53 R248W gain-of-function mutation suggest impaired homologous recombination repair in fragile histidine triad-negative sebaceous gland carcinomas.
Carcinoma
Differential susceptibility of renal carcinoma cell lines to tumor suppression by exogenous Fhit expression.
Carcinoma
Effect of fragile histidine triad gene on biologic properties of muco-epidermoid carcinoma cells.
Carcinoma
Epigenetic silencing contributes to frequent loss of the fragile histidine triad tumour suppressor in basal cell carcinomas.
Carcinoma
Epithelial and stromal genetic instability linked to tumor suppressor genes in ulcerative colitis-associated tumorigenesis.
Carcinoma
Fhit expression in gastric adenocarcinoma: correlation with disease stage and survival.
Carcinoma
Fhit expression in human gastric adenomas and intramucosal carcinomas: correlation with Mlh1 expression and gastric phenotype.
Carcinoma
Fhit protein expression in lung cancer studied by high-throughput tissue microarray.
Carcinoma
FHIT protein is expressed in benign mesothelium and has no clinical value in detecting carcinoma in body cavity effusions.
Carcinoma
Fhit Regulates EMT Targets through an EGFR/Src/ERK/Slug Signaling Axis in Human Bronchial Cells.
Carcinoma
Fragile histidine triad expression in oral squamous cell carcinoma and precursor lesions.
Carcinoma
Fragile histidine triad gene abnormalities in the pathogenesis of gallbladder carcinoma.
Carcinoma
Fragile histidine triad gene inactivation in lung cancer: the European Early Lung Cancer project.
Carcinoma
Fragile histidine triad transcription abnormalities and human papillomavirus E6-E7 mRNA expression in the development of cervical carcinoma.
Carcinoma
Frequent altered expression of fragile histidine triad protein in human colorectal adenomas.
Carcinoma
Hypermethylation and loss of heterozygosity of tumor suppressor genes on chromosome 3p in cervical cancer.
Carcinoma
Immunohistochemical assessment of Fhit protein expression in advanced gastric carcinomas in correlation with Helicobacter pylori infection and survival time.
Carcinoma
Immunohistochemical detection of cell cycle regulators, Fhit protein and apoptotic cells in parathyroid lesions.
Carcinoma
Immunohistochemical evaluation of Fhit protein expression in oral squamous cell carcinomas.
Carcinoma
Immunohistochemical expression of Fhit protein in Helicobacter pylori related chronic gastritis, gastric precancerous lesions and gastric carcinoma: correlation with conventional clinicopathologic parameters.
Carcinoma
Immunohistochemical FHIT expression still exists in early lesions of basal cell carcinoma.
Carcinoma
In silico analysis of fragile histidine triad involved in regression of carcinoma.
Carcinoma
Investigation of tumor suppressor genes apart from VHL on 3p by deletion mapping in sporadic clear cell renal cell carcinoma (cRCC).
Carcinoma
Loss of FHIT expression in gastric mucosa of patients with family histories of gastric cancer and Helicobacter pylori infection.
Carcinoma
Loss of fhit expression in invasive cervical carcinomas and intraepithelial lesions associated with invasive disease.
Carcinoma
Loss of FHIT expression in squamous cell carcinoma and premalignant lesions of the larynx.
Carcinoma
Loss of Fhit protein expression in high-grade and advanced stage endometrial carcinomas.
Carcinoma
Loss of fragile histidine triad (FHIT) expression and microsatellite instability in periocular sebaceous gland carcinoma in patients with Muir-Torre syndrome.
Carcinoma
Loss of fragile histidine triad gene expression is associated with progression of esophageal squamous cell carcinoma, but not with the patient's prognosis and smoking history.
Carcinoma
Loss of fragile histidine triad protein expression in inflammatory bowel disease.
Carcinoma
Loss of heterozygosity and microsatellite instabilities of fragile histidine triad gene in gastric carcinoma.
Carcinoma
Loss or reduction of Fhit expression in renal neoplasias: correlation with histogenic class.
Carcinoma
Low expression of fragile histidine triad gene correlates with high proliferation in head and neck squamous cell carcinoma.
Carcinoma
Methylation status of fragile histidine triad (FHIT) gene and its clinical impact on prognosis of patients with myelodysplastic syndrome.
Carcinoma
Microsatellite instability and loss of heterozygosity in oral squamous cell carcinoma in Malaysian population.
Carcinoma
Microsatellite instability and loss of heterozygosity of fragile histidine triad gene in lung hyperplastic lesions.
Carcinoma
Microsatellite instability is often observed in esophageal carcinoma patients with allelic loss in the FHIT/FRA3B locus.
Carcinoma
Reduced acetylated histone H4 is associated with promoter methylation of the fragile histidine triad gene in resected esophageal squamous cell carcinoma.
Carcinoma
Reduced Fhit expression in cervical carcinoma: correlation with tumor progression and poor prognosis.
Carcinoma
Reduced Fhit expression is associated with mismatch repair deficiency in human advanced colorectal carcinoma.
Carcinoma
Reduced Fhit expression occurs in the early stage of esophageal tumorigenesis: no correlation with p53 expression and apoptosis.
Carcinoma
Reduced Fhit protein expression and loss of heterozygosity at FHIT gene in tumours from smoking and asbestos-exposed lung cancer patients.
Carcinoma
Relationship between expression of P27, Fragile Histidine Triad (FHT), phosphatase and tensin homolog deleted on chromosome ten (PTEN), P73, and prognosis in esophageal squamous cell carcinoma.
Carcinoma
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in lung and cervical cancer cell lines.
Carcinoma
Restoration of fragile histidine triad expression restores Chk2 activity in response to ionizing radiation in oral squamous cell carcinoma cells.
Carcinoma
Restored expression of fragile histidine triad protein and tumorigenicity of cervical carcinoma cells.
Carcinoma
Significance of combined detection of p53 and FHIT in cervical carcinoma diagnosis.
Carcinoma
The methylation status and protein expression of CDH1, p16(INK4A), and fragile histidine triad in nonsmall cell lung carcinoma: epigenetic silencing, clinical features, and prognostic significance.
Carcinoma
The significance of fragile histidine triad protein as a molecular prognostic marker of bladder urothelial carcinoma.
Carcinoma
[Abnormal expression of fragile histidine triad (FHIT) and Mut S homolog 2 (MSH2) proteins in human sporadic colorectal carcinoma and their clinical significance]
Carcinoma
[Expression of the genes FHIT, Bcl-2 and Bax in breast infiltrating ductal carcinoma and clinicopathological significance thereof]
Carcinoma
[Expressions of FHIT and cyclin D1/CDK4 in oral cancer and oral precancerous lesions]
Carcinoma
[Fragile histidine triad protein expression and correlation with apoptosis in rectal carcinoma]
Carcinoma
[HPV detection and FHIT expression in esophageal squamous carcinoma from high incidence area in Cixian County]
Carcinoma
[Hypermethylation of fragile histidine triad gene and 3p14 allelic deletion in ovarian carcinomas]
Carcinoma
[Loss of exons of FHIT gene and FHIT protein expression in Yunnan tin miners with lung cancer]
Carcinoma
[Microsatellite instability and loss of heterozygosity of fragile histidine triad gene in laryngeal squamous cell carcinoma]
Carcinoma
[Relationship between hMSH2 and FHIT gene expression in non-small cell lung cancer]
Carcinoma
[Relationship between the expression of fragile histidine (FHIT) and the development of vulvar carcinoma]
Carcinoma
[Relationship between the reduction of FHIT expression and the development of cervical carcinoma]
Carcinoma
[Study on the relationship between LOH and MI of FHIT gene and the development of cervical carcinoma]
Carcinoma
[The relationship between expression of Fhit and biological behaviors of hypopharyngeal carcinoma]
Carcinoma in Situ
Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types.
Carcinoma in Situ
Reduced Fhit expression occurs in the early stage of esophageal tumorigenesis: no correlation with p53 expression and apoptosis.
Carcinoma in Situ
[Loss of exons of FHIT gene and FHIT protein expression in Yunnan tin miners with lung cancer]
Carcinoma, Basal Cell
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Carcinoma, Basal Cell
Epigenetic silencing contributes to frequent loss of the fragile histidine triad tumour suppressor in basal cell carcinomas.
Carcinoma, Basal Cell
Immunohistochemical FHIT expression still exists in early lesions of basal cell carcinoma.
Carcinoma, Ductal
[Expression of the genes FHIT, Bcl-2 and Bax in breast infiltrating ductal carcinoma and clinicopathological significance thereof]
Carcinoma, Ductal
[Loss of fragile histidine triad expression and metastasis in breast cancer]
Carcinoma, Hepatocellular
Aberrant fragile histidine triad gene transcripts in primary hepatocellular carcinoma and liver cirrhosis.
Carcinoma, Hepatocellular
Alterations of the fragile histidine triad gene in hepatitis C virus-associated hepatocellular carcinoma.
Carcinoma, Hepatocellular
Effect of fragile histidine triad gene transduction on proliferation and apoptosis of human hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Effect of interventional embolotherapy on FHIT and p16 expression in hepatocellular carcinoma patients.
Carcinoma, Hepatocellular
Evaluation of Relationship between Occurrence of Liver Cancer and Methylation of Fragile Histidine Triad (FHIT) and P16 Genes.
Carcinoma, Hepatocellular
Expression of fragile histidine triad in primary hepatocellular carcinoma and its relation with cell proliferation and apoptosis.
Carcinoma, Hepatocellular
FHIT overexpression in HepG2 hepatoma cells affects growth and cyclin D1 expression in vitro.
Carcinoma, Hepatocellular
Fragile histidine triad gene alterations are not essential for hepatocellular carcinoma development in South Korea.
Carcinoma, Hepatocellular
HIV-TAT-fused FHIT protein functions as a potential pro-apoptotic molecule in hepatocellular carcinoma cells.
Carcinoma, Hepatocellular
Loss of fragile histidine triad protein in human hepatocellular carcinoma.
Carcinoma, Hepatocellular
[Clinicopathological significance of aberrant methylation of the fragile histidine triad gene in patients with hepatocellular carcinoma]
Carcinoma, Mucoepidermoid
[The inhibition of fragile histidine triad gene on the proliferation and tumorigenicity of mucoepidermoid carcinoma cells]
Carcinoma, Neuroendocrine
Molecular alterations to human chromosome 3p loci in neuroendocrine lung tumors.
Carcinoma, Non-Small-Cell Lung
Clinicopathological significance of aberrant methylation of RARbeta2 at 3p24, RASSF1A at 3p21.3, and FHIT at 3p14.2 in patients with non-small cell lung cancer.
Carcinoma, Non-Small-Cell Lung
Clinicopathological significance of Fhit protein expression in stage I non-small cell lung carcinoma.
Carcinoma, Non-Small-Cell Lung
FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-?B/Slug-mediated PUMA reduction.
Carcinoma, Non-Small-Cell Lung
Fragile histidine triad protein expression in nonsmall cell lung cancer and correlation with Ki-67 and with p53.
Carcinoma, Non-Small-Cell Lung
Increased Sensitivity to Cisplatin in Non-Small Cell Lung Cancer Cell Lines after FHIT Gene Transfer.
Carcinoma, Non-Small-Cell Lung
Loss of FHIT function in lung cancer and preinvasive bronchial lesions.
Carcinoma, Renal Cell
Different immunohistochemical patterns of Fhit protein expression in renal neoplasms.
Carcinoma, Renal Cell
Differential susceptibility of renal carcinoma cell lines to tumor suppression by exogenous Fhit expression.
Carcinoma, Small Cell
Molecular alterations to human chromosome 3p loci in neuroendocrine lung tumors.
Carcinoma, Squamous Cell
Altered p16INK4a and Fhit expression in carcinogenesis and progression of human oral cancer.
Carcinoma, Squamous Cell
Decreased fragile histidine triad gene protein expression is associated with worse prognosis in oral squamous carcinoma.
Carcinoma, Squamous Cell
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Carcinoma, Squamous Cell
Fhit protein expression in lung cancer studied by high-throughput tissue microarray.
Carcinoma, Squamous Cell
Fragile histidine triad gene inactivation in lung cancer: the European Early Lung Cancer project.
Carcinoma, Squamous Cell
Hypermethylation and loss of heterozygosity of tumor suppressor genes on chromosome 3p in cervical cancer.
Carcinoma, Squamous Cell
Loss of FHIT expression in squamous cell carcinoma and premalignant lesions of the larynx.
Carcinoma, Squamous Cell
Low expression of fragile histidine triad gene correlates with high proliferation in head and neck squamous cell carcinoma.
Carcinoma, Squamous Cell
Microsatellite instability and loss of heterozygosity in oral squamous cell carcinoma in Malaysian population.
Carcinoma, Squamous Cell
Microsatellite instability and loss of heterozygosity of fragile histidine triad gene in lung hyperplastic lesions.
Carcinoma, Squamous Cell
Reduced Fhit expression occurs in the early stage of esophageal tumorigenesis: no correlation with p53 expression and apoptosis.
Carcinoma, Squamous Cell
[HPV detection and FHIT expression in esophageal squamous carcinoma from high incidence area in Cixian County]
Carcinoma, Squamous Cell
[Loss of exons of FHIT gene and FHIT protein expression in Yunnan tin miners with lung cancer]
Carcinoma, Squamous Cell
[Relationship between hMSH2 and FHIT gene expression in non-small cell lung cancer]
Cervical Intraepithelial Neoplasia
The role of human papillomavirus type 16 and the fragile histidine triad gene in the outcome of cervical neoplastic lesions.
Cholangiocarcinoma
Aberrant transcription of FHIT gene in intrahepatic cholangiocellular carcinomas induced by N-nitrosobis(2-oxopropyl)amine in hamsters.
Cholangiocarcinoma
Alteration of the fragile histidine triad gene in intrahepatic cholangiocarcinoma.
Cholangiocarcinoma
Fragile histidine triad (FHIT) suppresses proliferation and promotes apoptosis in cholangiocarcinoma cells by blocking PI3K-Akt pathway.
Cholangiocarcinoma
Inverse correlation of aberrant expression of fragile histidine triad (FHIT) protein with cyclin D1 protein and prognosis in Chinese patients with cholangiocarcinoma.
Cholangiocarcinoma
Promoter methylation and loss of coding exons of the fragile histidine triad (FHIT) gene in intrahepatic cholangiocarcinomas.
Chordoma
High-resolution whole-genome analysis of skull base chordomas implicates FHIT loss in chordoma pathogenesis.
Colitis, Ulcerative
Immunohistochemical expression of FHIT gene product in inflammatory bowel disease: significance and correlation with clinicopathological data.
Colitis, Ulcerative
Loss of fragile histidine triad protein expression in inflammatory bowel disease.
Colitis, Ulcerative
Overexpression of the fragile histidine triad (FHIT) gene in inflammatory bowel disease.
Colonic Neoplasms
Fhit protein inhibits cell growth by attenuating the signaling mediated by nuclear factor-kappaB in colon cancer cell lines.
Colorectal Neoplasms
Aberrant crypt focus and fragile histidine triad protein in sporadic colorectal carcinoma.
Colorectal Neoplasms
Abnormal Fhit protein expression and high frequency of microsatellite instability in sporadic colorectal cancer.
Colorectal Neoplasms
Absence of Msh2 protein expression is associated with alteration in the FHIT locus and Fhit protein expression in colorectal carcinoma.
Colorectal Neoplasms
Clinical significance of Fhit expression in development of colorectal carcinoma of various macroscopic types.
Colorectal Neoplasms
Decreased fragile histidine triad expression in colorectal cancer and its association with apoptosis inhibition.
Colorectal Neoplasms
FHIT protein expression and its relation to apoptosis, tumor histologic grade and prognosis in colorectal adenocarcinoma: an immunohistochemical and image analysis study.
Colorectal Neoplasms
Fhit protein expression in hereditary and sporadic colorectal cancers.
Colorectal Neoplasms
Fragile histidine triad (FHIT) gene is overexpressed in colorectal cancer.
Colorectal Neoplasms
Frequent altered expression of fragile histidine triad protein in human colorectal adenomas.
Colorectal Neoplasms
Loss of fragile histidine triad expression in colorectal carcinomas and premalignant lesions.
Colorectal Neoplasms
Reduced Fhit expression is associated with mismatch repair deficiency in human advanced colorectal carcinoma.
Colorectal Neoplasms
Usefulness of plasma epigenetic changes of five major genes involved in the pathogenesis of colorectal cancer.
Colorectal Neoplasms
[Abnormal expression of fragile histidine triad (FHIT) and Mut S homolog 2 (MSH2) proteins in human sporadic colorectal carcinoma and their clinical significance]
Colorectal Neoplasms
[Expression of nuclear factor-kappa-B/P65 and fragile histidine triad in colorectal carcinoma and clinical significance thereof]
Colorectal Neoplasms
[Impact of fragile histidine triad gene transfection on the proliferation and apoptosis of human colorectal cancer cell]
Crohn Disease
Genome-Wide Analysis of the DNA Methylation Profile Identifies the Fragile Histidine Triad (FHIT) Gene as a New Promising Biomarker of Crohn's Disease.
Crohn Disease
Immunohistochemical expression of FHIT gene product in inflammatory bowel disease: significance and correlation with clinicopathological data.
Crohn Disease
Loss of fragile histidine triad protein expression in inflammatory bowel disease.
Crohn Disease
Overexpression of the fragile histidine triad (FHIT) gene in inflammatory bowel disease.
Dentigerous Cyst
Alterations of FHIT and P53 genes in keratocystic odontogenic tumor, dentigerous and radicular cyst.
Dentigerous Cyst
Assessment of fragile histidine triad expression in ameloblastoma, odontogenic keratocyst and dentigerous cyst.
Digestive System Neoplasms
FHIT promotes the apoptosis of QBC939 by reducing the expression of cyclin D1.
Endometrial Neoplasms
Clinicopathological significance of fragile histidine triad transcription protein expression in endometrial carcinomas.
Endometrial Neoplasms
Fhit protein expression in endometrial cancers: no correlation with histological grade.
Endometrial Neoplasms
Loss of Fhit protein expression in high-grade and advanced stage endometrial carcinomas.
Endometrial Neoplasms
Upregulation of FHIT gene expression in endometrial carcinoma by RNA activation.
Epstein-Barr Virus Infections
Relationship between abnormality of FHIT gene and EBV infection in gastric cancer.
Esophageal Neoplasms
Aberrant methylation of Fragile Histidine Triad gene is associated with poor prognosis in early stage esophageal squamous cell carcinoma.
Esophageal Neoplasms
Effect of adenoviral transduction of the fragile histidine triad gene into esophageal cancer cells.
Esophageal Neoplasms
Immunohistochemical evaluation of p53, FHIT, and IGF2 gene expression in esophageal cancer.
Esophageal Neoplasms
[Association of fragile histidine triad gene (FHIT) with susceptibility to esophageal cancer. A preliminary study]
Esophageal Squamous Cell Carcinoma
Aberrant methylation of Fragile Histidine Triad gene is associated with poor prognosis in early stage esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Loss of fragile histidine triad gene expression is associated with progression of esophageal squamous cell carcinoma, but not with the patient's prognosis and smoking history.
Esophageal Squamous Cell Carcinoma
Reduced acetylated histone H4 is associated with promoter methylation of the fragile histidine triad gene in resected esophageal squamous cell carcinoma.
Esophageal Squamous Cell Carcinoma
Relationship between expression of P27, Fragile Histidine Triad (FHT), phosphatase and tensin homolog deleted on chromosome ten (PTEN), P73, and prognosis in esophageal squamous cell carcinoma.
Gallbladder Neoplasms
Fragile histidine triad (FHIT) gene and its association with p53 protein expression in the progression of gall bladder cancer.
Gastritis
Immunohistochemical expression of Fhit protein in Helicobacter pylori related chronic gastritis, gastric precancerous lesions and gastric carcinoma: correlation with conventional clinicopathologic parameters.
Glioblastoma
FHIT Gene Sequence Variants and Reduced Fhit Protein Expression in Glioblastoma Multiforme.
Head and Neck Neoplasms
Clinicopathological significance of the fragile histidine triad transcription protein expression in laryngeal carcinogenesis.
Hematologic Neoplasms
Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome.
Hematologic Neoplasms
Preclinical assessment of FHIT gene replacement therapy in human leukemia using a chimeric adenovirus, Ad5/F35.
Hematuria
Molecular analysis of the fragile histidine triad (FHIT) tumor suppressor gene in vesical tumors of cattle with chronic enzootic hematuria (CEH).
Hepatitis C
Alterations of the fragile histidine triad gene in hepatitis C virus-associated hepatocellular carcinoma.
Hodgkin Disease
Aberrant FHIT protein expression in classical Hodgkin's lymphoma: a potential marker.
Hodgkin Disease
[Expression of fragile histidine triad (FHIT) protein and its significance in diagnosing classical Hodgkin lymphoma]
Hypertension
Fragile Histidine Triad (FHIT), a Novel Modifier Gene in Pulmonary Arterial Hypertension.
Idiopathic Pulmonary Fibrosis
Aberrations in the fragile histidine triad (FHIT) gene in idiopathic pulmonary fibrosis.
Infections
Abnormal Fhit expression is an independent poor prognostic factor for cervical cancer.
Infections
Effect of FHIT loss and p53 mutation on HPV-infected lung carcinoma development.
Infections
Effect of fragile histidine triad gene transduction on proliferation and apoptosis of human hepatocellular carcinoma cells.
Infections
Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential.
Infections
Immunohistochemical assessment of Fhit protein expression in advanced gastric carcinomas in correlation with Helicobacter pylori infection and survival time.
Infections
Immunohistochemical expression of Fhit protein in Helicobacter pylori related chronic gastritis, gastric precancerous lesions and gastric carcinoma: correlation with conventional clinicopathologic parameters.
Infections
Loss of Fhit expression as a potential marker of malignant progression in preinvasive squamous cervical cancer.
Infections
Restored expression of fragile histidine triad protein and tumorigenicity of cervical carcinoma cells.
Infections
[Interaction between fragile histidine triad methylation, protein expression and human papillomavirus 16 infection in cervical carcinogenesis].
Inflammatory Bowel Diseases
Loss of fragile histidine triad protein expression in inflammatory bowel disease.
Inflammatory Bowel Diseases
Overexpression of the fragile histidine triad (FHIT) gene in inflammatory bowel disease.
Keratosis, Actinic
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Kidney Neoplasms
Different immunohistochemical patterns of Fhit protein expression in renal neoplasms.
Kidney Neoplasms
Expression of the fragile histidine triad gene in normal rat tissues and human kidney cancer cell lines.
Leukemia
Methylation status of the FHIT gene in the transformed human mesenchymal F6 stem cell line.
Leukemia, Myeloid, Acute
Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome.
Leukemia-Lymphoma, Adult T-Cell
Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases.
Liver Cirrhosis
Aberrant fragile histidine triad gene transcripts in primary hepatocellular carcinoma and liver cirrhosis.
Liver Neoplasms
Association of FHIT expression and FHIT gene hypermethylation with liver cancer risk: a PRISMA-compliant meta-analysis.
Liver Neoplasms
Evaluation of Relationship between Occurrence of Liver Cancer and Methylation of Fragile Histidine Triad (FHIT) and P16 Genes.
Liver Neoplasms
HIV-TAT-fused FHIT protein functions as a potential pro-apoptotic molecule in hepatocellular carcinoma cells.
Liver Neoplasms
Relationship between Methylation of FHIT and CDH13 Gene Promoter Region and Liver Cancer.
Lung Neoplasms
Aberrant methylation of the FHIT gene in chronic smokers with early stage squamous cell carcinoma of the lung.
Lung Neoplasms
Aberration of FHIT gene is associated with increased tumor proliferation and decreased apoptosis-clinical evidence in lung and head and neck carcinomas.
Lung Neoplasms
Aberrations in the fragile histidine triad(FHIT) gene may be involved in lung carcinogenesis in patients with chronic pulmonary tuberculosis.
Lung Neoplasms
Absence of Fhit protein in primary lung tumors and cell lines with FHIT gene abnormalities.
Lung Neoplasms
Characterization of a multiple epigenetic marker panel for lung cancer detection and risk assessment in plasma.
Lung Neoplasms
Clinicopathological significance of aberrant methylation of RARbeta2 at 3p24, RASSF1A at 3p21.3, and FHIT at 3p14.2 in patients with non-small cell lung cancer.
Lung Neoplasms
Coexpression of fragile histidine triad and c-kit is relevant for prediction of survival in patients with small cell lung cancer.
Lung Neoplasms
Decreased fragile histidine triad gene messenger RNA expression in lung cancer.
Lung Neoplasms
Dose-dependent effect of FHIT-inducible expression in Calu-1 lung cancer cell line.
Lung Neoplasms
Early loss of Fhit in the respiratory tract of rodents exposed to environmental cigarette smoke.
Lung Neoplasms
Effect of FHIT loss and p53 mutation on HPV-infected lung carcinoma development.
Lung Neoplasms
Establishment of two data mining models of lung cancer screening based on three gene promoter methylations combined with telomere damage.
Lung Neoplasms
FHIT loss confers cisplatin resistance in lung cancer via the AKT/NF-?B/Slug-mediated PUMA reduction.
Lung Neoplasms
Fhit protein expression in lung cancer studied by high-throughput tissue microarray.
Lung Neoplasms
Fhit, a tumor suppressor protein, induces autophagy via 14-3-3? in non-small cell lung cancer cells.
Lung Neoplasms
Fhit-Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells.
Lung Neoplasms
Fragile histidine triad gene inactivation in lung cancer: the European Early Lung Cancer project.
Lung Neoplasms
Fragile Histidine Triad Mediated Tumor Suppression of Lung Cancer by Targeting Multiple Components of the Ras/Rho GTPase Molecular Switch.
Lung Neoplasms
Fragile histidine triad protein expression in nonsmall cell lung cancer and correlation with Ki-67 and with p53.
Lung Neoplasms
Frequent allelic deletion at the FHIT locus associated with p53 overexpression in squamous cell carcinoma subtype of Taiwanese non-small-cell lung cancers.
Lung Neoplasms
Frequent FHIT gene loss of heterozygosity in human papillomavirus-infected non-smoking female lung cancer in Taiwan.
Lung Neoplasms
Increased Sensitivity to Cisplatin in Non-Small Cell Lung Cancer Cell Lines after FHIT Gene Transfer.
Lung Neoplasms
Induction of apoptosis by tumor suppressor FHIT via death receptor signaling pathway in human lung cancer cells.
Lung Neoplasms
Lack of association of fragile histidine triad (FHIT) polymorphisms with lung cancer in the Korean population.
Lung Neoplasms
Loss of Fhit expression in non-small-cell lung cancer: correlation with molecular genetic abnormalities and clinicopathological features.
Lung Neoplasms
Loss of FHIT protein expression is related to high proliferation, low apoptosis and worse prognosis in non-small-cell lung cancer.
Lung Neoplasms
Loss of fragile histidine triad gene expression in advanced lung cancer is consequent to allelic loss at 3p14 locus and promoter methylation.
Lung Neoplasms
Lung cancer susceptibility in Fhit-deficient mice is increased by Vhl haploinsufficiency.
Lung Neoplasms
Mutation analysis of the FHIT gene in bronchoscopic specimens from patients with suspected lung cancer.
Lung Neoplasms
Prognostic relevance of fragile histidine triad protein expression in patients with small cell lung cancer.
Lung Neoplasms
Reduced Fhit protein expression and loss of heterozygosity at FHIT gene in tumours from smoking and asbestos-exposed lung cancer patients.
Lung Neoplasms
Roles of Fhit and p53 in Taiwanese surgically treated non-small-cell lung cancers.
Lung Neoplasms
The apoptotic pathway triggered by the Fhit protein in lung cancer cell lines is not affected by Bcl-2 or Bcl-x(L) overexpression.
Lung Neoplasms
The fragile histidine triad gene: a molecular link between cigarette smoking and cervical cancer.
Lung Neoplasms
The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control.
Lung Neoplasms
[Aberrant promoter methylation of tumor suppressor genes in serum from lung cancer patients: frequency and correlation with clinicopathological characteristics]
Lung Neoplasms
[Alterations of FHIT gene and p16 gene in lung cancer and metastatic hilar lymph nodes]
Lung Neoplasms
[Clinicopathological analysis of loss of fragile histidine triad expression in lung cancer].
Lung Neoplasms
[Ectogenous fragile histidine triad gene inhibits the malignant phenotype of human lung cancer cell line A549 in vitro and in vivo]
Lung Neoplasms
[FHIT protein expression during malignant transformation of human bronchial epithelial cells induced by NNK.]
Lung Neoplasms
[Loss of exons of FHIT gene and FHIT protein expression in Yunnan tin miners with lung cancer]
Lung Neoplasms
[Relationship between hMSH2 and FHIT gene expression in non-small cell lung cancer]
Lung Neoplasms
[The biological significance of FHIT protein expression in lung cancer and precancerous tissues detected by tissue microarray.]
Lymphatic Metastasis
Absence of Msh2 protein expression is associated with alteration in the FHIT locus and Fhit protein expression in colorectal carcinoma.
Lymphatic Metastasis
FHIT expression and hypermethylation in esophageal squamous cell carcinoma.
Lymphatic Metastasis
Fhit protein expression in lung cancer studied by high-throughput tissue microarray.
Lymphatic Metastasis
[Abnormal expression of fragile histidine triad (FHIT) and Mut S homolog 2 (MSH2) proteins in human sporadic colorectal carcinoma and their clinical significance]
Lymphatic Metastasis
[Clinicopathological analysis of loss of fragile histidine triad expression in lung cancer].
Lymphatic Metastasis
[Loss of fragile histidine triad expression and metastasis in breast cancer]
Lymphatic Metastasis
[Relationship between hMSH2 and FHIT gene expression in non-small cell lung cancer]
Lymphatic Metastasis
[Relationship between the reduction of FHIT expression and the development of cervical carcinoma]
Lymphatic Metastasis
[The biological significance of FHIT protein expression in lung cancer and precancerous tissues detected by tissue microarray.]
Lymphoma
Aberrant FHIT protein expression in classical Hodgkin's lymphoma: a potential marker.
Lymphoma, B-Cell
Decreased FHIT protein expression correlates with a worse prognosis in patients with diffuse large B-cell lymphoma.
Lymphoma, B-Cell
High throughput tissue microarray analysis of FHIT expression in diffuse large cell B-cell lymphoma from Saudi Arabia.
Lymphoma, Large B-Cell, Diffuse
Decreased FHIT protein expression correlates with a worse prognosis in patients with diffuse large B-cell lymphoma.
Lymphoma, Large B-Cell, Diffuse
High throughput tissue microarray analysis of FHIT expression in diffuse large cell B-cell lymphoma from Saudi Arabia.
Lymphoma, T-Cell, Cutaneous
Restoration of Fragile Histidine Triad (FHIT) Expression Inhibits Cell Growth and Induces Apoptosis in Cutaneous T-cell Lymphoma Cell Line.
Melanoma
Loss of heterozygosity on chromosomes 3, 9, 13, and 17, including the retinoblastoma locus, in uveal melanoma.
Mesothelioma
Role of fragile histidine triad protein expression in pathogenesis of malignant pleural mesothelioma.
Mesothelioma, Malignant
Role of fragile histidine triad protein expression in pathogenesis of malignant pleural mesothelioma.
Mouth Neoplasms
[Expression and significance of fragile histidine triad in oral cancer and precancerous lesions]
Muir-Torre Syndrome
Loss of fragile histidine triad (FHIT) expression and microsatellite instability in periocular sebaceous gland carcinoma in patients with Muir-Torre syndrome.
Multiple Myeloma
Methylation status of fragile histidine triad (FHIT) gene and its clinical impact on prognosis of patients with multiple myeloma.
Myelodysplastic Syndromes
Expression and methylation status of the FHIT gene in acute myeloid leukemia and myelodysplastic syndrome.
Myelodysplastic Syndromes
Methylation status of fragile histidine triad (FHIT) gene and its clinical impact on prognosis of patients with myelodysplastic syndrome.
Myelodysplastic Syndromes
[Alteration of methylation status of fragile histidine triad gene promoter in patients with myelodysplastic syndrome]
Nasopharyngeal Carcinoma
Expression of Fragile Histidine Triad (FHIT) and WW-Domain Oxidoreductase Gene (WWOX) in Nasopharyngeal Carcinoma.
Nasopharyngeal Carcinoma
Mutation and abnormal expression of the fragile histidine triad gene in nasopharyngeal carcinoma.
Neoplasm Metastasis
Absence of Msh2 protein expression is associated with alteration in the FHIT locus and Fhit protein expression in colorectal carcinoma.
Neoplasm Metastasis
Clinicopathological significance and prognostic value of leukemia-related protein 16 expression in invasive ductal breast carcinoma.
Neoplasm Metastasis
Clinicopathological significance of FHIT protein expression in gastric adenocarcinoma patients.
Neoplasm Metastasis
FHIT expression and hypermethylation in esophageal squamous cell carcinoma.
Neoplasm Metastasis
Fhit protein expression in lung cancer studied by high-throughput tissue microarray.
Neoplasm Metastasis
Fragile histidine triad (FHIT) gene is overexpressed in colorectal cancer.
Neoplasm Metastasis
Immunohistochemical assessment of Fhit protein expression in advanced gastric carcinomas in correlation with Helicobacter pylori infection and survival time.
Neoplasm Metastasis
Prognostic value of EUS combined with MSCT in predicting the recurrence and metastasis of patients with gastric cancer.
Neoplasm Metastasis
[Abnormal expression of fragile histidine triad (FHIT) and Mut S homolog 2 (MSH2) proteins in human sporadic colorectal carcinoma and their clinical significance]
Neoplasm Metastasis
[Clinicopathological analysis of loss of fragile histidine triad expression in lung cancer].
Neoplasm Metastasis
[Frequent loss of fragile histidine triad gene transcripts in lung cancer]
Neoplasm Metastasis
[Loss of fragile histidine triad expression and metastasis in breast cancer]
Neoplasm Metastasis
[Relationship between hMSH2 and FHIT gene expression in non-small cell lung cancer]
Neoplasm Metastasis
[Relationship between the expression of fragile histidine (FHIT) and the development of vulvar carcinoma]
Neoplasm Metastasis
[Relationship between the reduction of FHIT expression and the development of cervical carcinoma]
Neoplasm Metastasis
[The biological significance of FHIT protein expression in lung cancer and precancerous tissues detected by tissue microarray.]
Neoplasms
5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer.
Neoplasms
A mouse model of the fragile gene FHIT: From carcinogenesis to gene therapy and cancer prevention.
Neoplasms
Aberrant FHIT mRNA transcripts are present in malignant and normal haematopoiesis, but absence of FHIT protein is restricted to leukaemia.
Neoplasms
Aberrant FHIT protein expression in classical Hodgkin's lymphoma: a potential marker.
Neoplasms
Aberration of the enzymatic activity of Fhit tumor suppressor protein enhances cancer cell death upon photodynamic therapy similarly to that driven by wild-type Fhit.
Neoplasms
Aberrations in the fragile histidine triad(FHIT) gene may be involved in lung carcinogenesis in patients with chronic pulmonary tuberculosis.
Neoplasms
Abnormal FHIT gene transcript and c-myc and c-erbB2 amplification in breast cancer.
Neoplasms
Abnormal fragile histidine triad (Fhit) expression in invasive cervical adenocarcinoma: association with tumor aggressiveness.
Neoplasms
Abnormalities of fragile histidine triad genomic and complementary DNAs in cervical cancer: association with human papillomavirus type.
Neoplasms
Absence of FHIT expression is associated with apoptosis inhibition in colorectal cancer.
Neoplasms
Absence of Fhit protein in primary lung tumors and cell lines with FHIT gene abnormalities.
Neoplasms
Absence of Msh2 protein expression is associated with alteration in the FHIT locus and Fhit protein expression in colorectal carcinoma.
Neoplasms
Activation of G?q subunits up-regulates the expression of the tumor suppressor Fhit.
Neoplasms
Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma.
Neoplasms
Allelic deletion analysis of the FHIT gene predicts poor survival in non-small cell lung cancer.
Neoplasms
Alteration of the fragile histidine triad gene in intrahepatic cholangiocarcinoma.
Neoplasms
Alterations of the fragile histidine triad gene, FHIT, and its encoded products contribute to testicular germ cell tumorigenesis.
Neoplasms
Altered expression of Fhit in carcinoma and precarcinomatous lesions of the esophagus.
Neoplasms
Altered gene expression in immunogenic poorly differentiated thyroid carcinomas from RET/PTC3p53-/- mice.
Neoplasms
Altered p16INK4a and Fhit expression in carcinogenesis and progression of human oral cancer.
Neoplasms
Analysis of FHIT allelic imbalance/loss of heterozygosity and FHIT expression in cutaneous squamous cell carcinomas.
Neoplasms
Analysis of FHIT Gene Methylation in Egyptian Breast Cancer Women: Association with Clinicopathological Features.
Neoplasms
Association between germline variation in the FHIT gene and prostate cancer in Caucasians and African Americans.
Neoplasms
Biochemical and immunochemical characterisation of human diadenosine triphosphatase provides evidence for its identification with the tumour suppressor Fhit protein.
Neoplasms
Cancer prevention and therapy in a preclinical mouse model: impact of FHIT viruses.
Neoplasms
Characterization of a multiple epigenetic marker panel for lung cancer detection and risk assessment in plasma.
Neoplasms
Chromosome 3p allele loss in early invasive breast cancer: detailed mapping and association with clinicopathological features.
Neoplasms
Clinicopathological significance and prognostic value of leukemia-related protein 16 expression in invasive ductal breast carcinoma.
Neoplasms
Clinicopathological significance of FHIT protein expression in gastric adenocarcinoma patients.
Neoplasms
Clinicopathological significance of Fhit protein expression in stage I non-small cell lung carcinoma.
Neoplasms
Clinicopathological significance of fragile histidine triad transcription protein expression in breast carcinoma.
Neoplasms
Clinicopathological significance of fragile histidine triad transcription protein expression in endometrial carcinomas.
Neoplasms
Clinicopathological significance of the fragile histidine triad transcription protein expression in laryngeal carcinogenesis.
Neoplasms
Comparative analysis of loss of heterozygosity of specific chromosome 3, 13, 17, and X loci and TP53 mutations in human epithelial ovarian cancer.
Neoplasms
Comparative genomic mapping of the bovine Fragile Histidine Triad (FHIT) tumour suppressor gene: characterization of a 2 Mb BAC contig covering the locus, complete annotation of the gene, analysis of cDNA and of physiological expression profiles.
Neoplasms
Computational Survey of FHIT, A Putative Human Tumor Suppressor, Truncates Structure.
Neoplasms
Cytogenetic studies of 24 renal epithelial tumors with von Hippel-Lindau and fragile histidine triad protein expression correlation.
Neoplasms
Decreased fragile histidine triad gene protein expression is associated with worse prognosis in oral squamous carcinoma.
Neoplasms
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Neoplasms
Deletion of the FHIT gene in human colorectal cancer is independent of high-risk HPV infection.
Neoplasms
Deletions of BRCA1/2 and p53 R248W gain-of-function mutation suggest impaired homologous recombination repair in fragile histidine triad-negative sebaceous gland carcinomas.
Neoplasms
Development of spontaneous tumours and intestinal lesions in Fhit gene knockout mice.
Neoplasms
Di-, tri- and tetra-5'-O-phosphorothioadenosyl substituted polyols as inhibitors of Fhit: Importance of the alpha-beta bridging oxygen and beta phosphorus replacement.
Neoplasms
Different immunohistochemical patterns of Fhit protein expression in renal neoplasms.
Neoplasms
Dose-dependent effect of FHIT-inducible expression in Calu-1 lung cancer cell line.
Neoplasms
Down-regulation of FHIT inhibits apoptosis of colorectal cancer: mechanism and clinical implication.
Neoplasms
Effect of adenoviral transduction of the fragile histidine triad gene into esophageal cancer cells.
Neoplasms
Effect of exogenous E2F-1 on the expression of common chromosome fragile site genes, FHIT and WWOX.
Neoplasms
Effect of fragile histidine triad gene on biologic properties of muco-epidermoid carcinoma cells.
Neoplasms
Effect of regulated expression of the fragile histidine triad gene on cell cycle and proliferation.
Neoplasms
Enlightened protein: Fhit tumor suppressor protein structure and function and its role in the toxicity of protoporphyrin IX-mediated photodynamic reaction.
Neoplasms
Epigenetic silencing contributes to frequent loss of the fragile histidine triad tumour suppressor in basal cell carcinomas.
Neoplasms
Epithelial and stromal genetic instability linked to tumor suppressor genes in ulcerative colitis-associated tumorigenesis.
Neoplasms
Evaluation of influence of Ap(4)A analogues on Fhit-positive HEK293T cells; cytotoxicity and ability to induce apoptosis.
Neoplasms
Expression and Prognostic Role of FHIT, Fibronectin, and PTEN in Hepatocellular Carcinoma.
Neoplasms
Expression and simple, one-step purification of fragile histidine triad (Fhit) tumor suppressor mutant forms in Escherichia coli and their interaction with protoporphyrin IX
Neoplasms
Expression and simple, one-step purification of fragile histidine triad (Fhit) tumor suppressor mutant forms in Escherichia coli and their interaction with protoporphyrin IX.
Neoplasms
Expression characteristics of FHIT, p53, BRCA2 and MLH1 in families with a history of oesophageal cancer in a region with a high incidence of oesophageal cancer.
Neoplasms
Expression of Fhit, cell adhesion molecules and matrix metalloproteinases in atypical adenomatous hyperplasia and pulmonary adenocarcinoma.
Neoplasms
Expression of fragile histidine triad in primary hepatocellular carcinoma and its relation with cell proliferation and apoptosis.
Neoplasms
Expression of Ki-67, galectin-3, fragile histidine triad, and parafibromin in malignant and benign parathyroid tumors.
Neoplasms
Expression of the fragile histidine triad gene in normal rat tissues and human kidney cancer cell lines.
Neoplasms
Expressions of miR-30c and let-7a are inversely correlated with HMGA2 expression in squamous cell carcinoma of the vulva.
Neoplasms
FHIT and TSG101 in thyroid tumours: aberrant transcripts reflect rare abnormal RNA processing events of uncertain pathogenetic or clinical significance.
Neoplasms
Fhit delocalizes annexin a4 from plasma membrane to cytosol and sensitizes lung cancer cells to paclitaxel.
Neoplasms
FHIT expression in clear cell renal carcinomas: versatility of protein levels and correlation with survival.
Neoplasms
Fhit expression in gastric adenocarcinoma: correlation with disease stage and survival.
Neoplasms
Fhit expression in human gastric adenomas and intramucosal carcinomas: correlation with Mlh1 expression and gastric phenotype.
Neoplasms
Fhit expression protects against HER2-driven breast tumor development: unraveling the molecular interconnections.
Neoplasms
FHIT gene and flanking region on chromosome 3p are subjected to extensive allelic loss in Egyptian breast cancer patients.
Neoplasms
FHIT gene expression in human ovarian, endometrial, and cervical cancer cell lines.
Neoplasms
FHIT gene expression is repressed by mitogenic signaling through the PI3K/AKT/FOXO pathway.
Neoplasms
FHIT Gene Sequence Variants and Reduced Fhit Protein Expression in Glioblastoma Multiforme.
Neoplasms
Fhit interaction with ferredoxin reductase triggers generation of reactive oxygen species and apoptosis of cancer cells.
Neoplasms
FHIT loss of function in human primary breast cancer correlates with advanced stage of the disease.
Neoplasms
FHIT loss-induced DNA damage creates optimal APOBEC substrates: Insights into APOBEC-mediated mutagenesis.
Neoplasms
Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential.
Neoplasms
Fhit Nuclear Import Following EGF Stimulation Sustains Proliferation of Breast Cancer Cells.
Neoplasms
FHIT promoter DNA methylation and expression analysis in childhood acute lymphoblastic leukemia.
Neoplasms
FHIT protein expression and its relation to apoptosis, tumor histologic grade and prognosis in colorectal adenocarcinoma: an immunohistochemical and image analysis study.
Neoplasms
Fhit protein expression in endometrial cancers: no correlation with histological grade.
Neoplasms
Fhit protein expression in human gastric cancer and related precancerous lesions.
Neoplasms
Fhit protein inhibits cell growth by attenuating the signaling mediated by nuclear factor-kappaB in colon cancer cell lines.
Neoplasms
FHIT protein is expressed in benign mesothelium and has no clinical value in detecting carcinoma in body cavity effusions.
Neoplasms
Fhit protein is preferentially expressed in the nucleus of monocyte-derived cells and its possible biological significance.
Neoplasms
Fhit Regulates EMT Targets through an EGFR/Src/ERK/Slug Signaling Axis in Human Bronchial Cells.
Neoplasms
FHIT suppresses epithelial-mesenchymal transition (EMT) and metastasis in lung cancer through modulation of microRNAs.
Neoplasms
Fhit, a putative tumor suppressor in humans, is a dinucleoside 5',5"'-P1,P3-triphosphate hydrolase.
Neoplasms
Fhit, a tumor suppressor protein, induces autophagy via 14-3-3? in non-small cell lung cancer cells.
Neoplasms
Fhit-Fdxr interaction in the mitochondria: modulation of reactive oxygen species generation and apoptosis in cancer cells.
Neoplasms
FHITlow /pHER2high signature in non-small cell lung cancer is predictive of anti-HER2 molecule efficacy.
Neoplasms
Fluorimetric detection of enzymatic activity associated with the human tumor suppressor Fhit protein.
Neoplasms
Folate deficiency and aberrant DNA methylation and expression of FHIT gene were associated with cervical pathogenesis.
Neoplasms
Fragile histidine triad (FHIT) suppresses proliferation and promotes apoptosis in cholangiocarcinoma cells by blocking PI3K-Akt pathway.
Neoplasms
Fragile histidine triad expression delays tumor development and induces apoptosis in human pancreatic cancer.
Neoplasms
Fragile histidine triad gene abnormalities in the pathogenesis of gallbladder carcinoma.
Neoplasms
Fragile histidine triad gene expression in primary prostate cancer and in an in vitro model.
Neoplasms
Fragile histidine triad gene inactivation in lung cancer: the European Early Lung Cancer project.
Neoplasms
Fragile Histidine Triad Mediated Tumor Suppression of Lung Cancer by Targeting Multiple Components of the Ras/Rho GTPase Molecular Switch.
Neoplasms
Fragile histidine triad protein expression in nonsmall cell lung cancer and correlation with Ki-67 and with p53.
Neoplasms
Fragile histidine triad protein, WW domain-containing oxidoreductase protein Wwox, and activator protein 2gamma expression levels correlate with basal phenotype in breast cancer.
Neoplasms
Fragile histidine triad protein: structure, function, and its association with tumorogenesis.
Neoplasms
Fragile histidine triad transcription abnormalities and human papillomavirus E6-E7 mRNA expression in the development of cervical carcinoma.
Neoplasms
Frequent allelic deletion at the FHIT locus associated with p53 overexpression in squamous cell carcinoma subtype of Taiwanese non-small-cell lung cancers.
Neoplasms
Frequent altered expression of fragile histidine triad protein in human colorectal adenomas.
Neoplasms
Frequent epigenetic silencing of the FHIT gene in penile squamous cell carcinomas.
Neoplasms
Frequent silencing of fragile histidine triad gene (FHIT) in Burkitt's lymphoma is associated with aberrant hypermethylation.
Neoplasms
Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit.
Neoplasms
Germinal epimutation of Fragile Histidine Triad (FHIT) gene is associated with progression to acute and chronic adult T-cell leukemia diseases.
Neoplasms
Helicobacter pylori infection and family history of gastric cancer decrease expression of FHIT tumor suppressor gene in gastric mucosa of dyspeptic patients.
Neoplasms
High-Risk HPV Infection and CIN Grade Correlates to the Expression of c-myc, CD4+, FHIT, E-cadherin, Ki-67, and p16INK4a.
Neoplasms
HIV-TAT-fused FHIT protein functions as a potential pro-apoptotic molecule in hepatocellular carcinoma cells.
Neoplasms
Homozygous deletion but not mutation of exons 5 and 8 of the fragile histidine triad (FHIT) gene is associated with features of differentiated thyroid carcinoma.
Neoplasms
Homozygous deletions on the short arm of chromosome 3 in human oral squamous cell carcinomas.
Neoplasms
Human diadenosine triphosphate hydrolase: preliminary characterisation and comparison with the Fhit protein, a human tumour suppressor.
Neoplasms
Identification of the expression profile of apoptotic esophageal cancer cells by adenoviral-fragile histidine triad treatment.
Neoplasms
Identification of unstable sequences within the common fragile site at 3p14.2: implications for the mechanism of deletions within fragile histidine triad gene/common fragile site at 3p14.2 in tumors.
Neoplasms
Immunohistochemical assessment of Fhit protein expression in advanced gastric carcinomas in correlation with Helicobacter pylori infection and survival time.
Neoplasms
Immunohistochemical evaluation of p53, FHIT, and IGF2 gene expression in esophageal cancer.
Neoplasms
Immunohistochemical expression of Fhit protein in Helicobacter pylori related chronic gastritis, gastric precancerous lesions and gastric carcinoma: correlation with conventional clinicopathologic parameters.
Neoplasms
Impact of decitabine on immunohistochemistry expression of the putative tumor suppressor genes FHIT, WWOX, FUS1 and PTEN in clinical tumor samples.
Neoplasms
Implication of mitochondrial involvement in apoptotic activity of fragile histidine triad gene: application of synchronous luminescence spectroscopy.
Neoplasms
In silico study of fragile histidine triad interaction domains with MDM2 and p53.
Neoplasms
In vitro inhibition of the enzymatic activity of tumor suppressor FHIT gene product by carcinogenic transition metals.
Neoplasms
Inactivation of the human fragile histidine triad gene at 3p14.2 in monochromosomal human/mouse microcell hybrid-derived severe combined immunodeficient mouse tumors.
Neoplasms
Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression.
Neoplasms
Investigation of mutations and expression of the FHIT gene in Turkish patients with brain metastases derived from non-small cell lung cancer.
Neoplasms
Investigation of tumor suppressor genes apart from VHL on 3p by deletion mapping in sporadic clear cell renal cell carcinoma (cRCC).
Neoplasms
Involvement of the Fhit gene in the ionizing radiation-activated ATR/CHK1 pathway.
Neoplasms
Lack of association of fragile histidine triad (FHIT) polymorphisms with lung cancer in the Korean population.
Neoplasms
Location of candidate tumour suppressor gene loci at chromosomes 3p, 8p and 9p for oral squamous cell carcinomas.
Neoplasms
Loss of FHIT expression in breast cancer is correlated with poor prognostic markers.
Neoplasms
Loss of FHIT expression in gastric mucosa of patients with family histories of gastric cancer and Helicobacter pylori infection.
Neoplasms
Loss of fhit expression in invasive cervical carcinomas and intraepithelial lesions associated with invasive disease.
Neoplasms
Loss of Fhit expression in testicular germ cell tumors and intratubular germ cell neoplasia.
Neoplasms
Loss of FHIT protein expression correlates with disease progression and poor differentiation in gastric cancer.
Neoplasms
Loss of Fhit protein expression in high-grade and advanced stage endometrial carcinomas.
Neoplasms
Loss of FHIT protein expression is related to high proliferation, low apoptosis and worse prognosis in non-small-cell lung cancer.
Neoplasms
Loss of fragile histidine triad (FHIT) expression and microsatellite instability in periocular sebaceous gland carcinoma in patients with Muir-Torre syndrome.
Neoplasms
Loss of fragile histidine triad expression in colorectal carcinomas and premalignant lesions.
Neoplasms
Loss of fragile histidine triad gene expression is associated with progression of esophageal squamous cell carcinoma, but not with the patient's prognosis and smoking history.
Neoplasms
Loss of heterozygosity in the fragile histidine triad (FHIT) locus and expression analysis of FHIT protein in patients with breast disorders.
Neoplasms
Loss of heterozygosity on chromosomes 3, 9, 13, and 17, including the retinoblastoma locus, in uveal melanoma.
Neoplasms
Loss or reduction of Fhit expression in renal neoplasias: correlation with histogenic class.
Neoplasms
Low expression of fragile histidine triad gene correlates with high proliferation in head and neck squamous cell carcinoma.
Neoplasms
Lung cancer susceptibility in Fhit-deficient mice is increased by Vhl haploinsufficiency.
Neoplasms
MAD analysis of FHIT, a putative human tumor suppressor from the HIT protein family.
Neoplasms
Mechanisms shaping the mutational landscape of the FRA3B/FHIT-deficient cancer genome.
Neoplasms
Methylation Analysis of Several Tumour Suppressor Genes Shows a Low Frequency of Methylation of CDKN2A and RARB in Uveal Melanomas.
Neoplasms
Methylation status of the FHIT gene in the transformed human mesenchymal F6 stem cell line.
Neoplasms
Microarray sampling-platform fabrication using bubble-jet technology for a biochip system.
Neoplasms
microRNA-143 protects cells from DNA damage-induced killing by downregulating FHIT expression.
Neoplasms
Microsatellite instability and loss of heterozygosity in oral squamous cell carcinoma in Malaysian population.
Neoplasms
Molecular analysis of the fragile histidine triad (FHIT) tumor suppressor gene in vesical tumors of cattle with chronic enzootic hematuria (CEH).
Neoplasms
Molecular and epigenetic analysis of the fragile histidine triad tumour suppressor gene in equine sarcoids.
Neoplasms
Molecular diagnosis and prognostic significance of lymph node micrometastasis in patients with histologically node-negative non-small cell lung cancer.
Neoplasms
Multiple Patterns of FHIT Gene Homozygous Deletion in Egyptian Breast Cancer Patients.
Neoplasms
Multiple regions with allelic loss at chromosome 3 in superficial multifocal bladder tumors.
Neoplasms
Mutation analysis of the FHIT gene in bronchoscopic specimens from patients with suspected lung cancer.
Neoplasms
Mutational and promoter hypermethylation status of FHIT gene in breast cancer patients of Kashmir.
Neoplasms
N-Terminal Domain of Fragile Histidine Triad Exerts Potent Cytotoxic Effect in HT1080 Cells and Increases Doxorubicin Cytotoxicity.
Neoplasms
New interactions between tumor suppressor Fhit protein and a nonhydrolyzable analog of its AP4 A substrate.
Neoplasms
Potential cancer therapy with the fragile histidine triad gene: review of the preclinical studies.
Neoplasms
Preclinical assessment of FHIT gene replacement therapy in human leukemia using a chimeric adenovirus, Ad5/F35.
Neoplasms
Prevalence of fragile histidine triad expression in tumors from saudi arabia: a tissue microarray analysis.
Neoplasms
Primary cervical carcinomas show 2 common regions of deletion at 3P, 1 within the FHIT gene: evaluation of allelic imbalance at FHIT, RB1 and TP53 in relation to survival.
Neoplasms
Prognostic relevance of fragile histidine triad protein expression in patients with small cell lung cancer.
Neoplasms
Prognostic value of FHIT, CTNNB1, and MUC1 expression in non-small cell lung cancer.
Neoplasms
Promoter hypermethylation of p16INK4a, E-cadherin, O6-MGMT, DAPK and FHIT in adenocarcinomas of the esophagus, esophagogastric junction and proximal stomach.
Neoplasms
Promoter methylation and loss of coding exons of the fragile histidine triad (FHIT) gene in intrahepatic cholangiocarcinomas.
Neoplasms
Promoter methylation status of the FHIT gene and Fhit expression: Association with HER2/neu status in breast cancer patients.
Neoplasms
Protein expression of Fragile Histidine Triad and cyclooxgenase-2 in serrated neoplasia of the colorectum.
Neoplasms
Protein expression profiling identifies cyclophilin A as a molecular target in Fhit-mediated tumor suppression.
Neoplasms
Purification and crystallization of complexes modeling the active state of the fragile histidine triad protein.
Neoplasms
Re-splicing of mature mRNA in cancer cells promotes activation of distant weak alternative splice sites.
Neoplasms
Reduced acetylated histone H4 is associated with promoter methylation of the fragile histidine triad gene in resected esophageal squamous cell carcinoma.
Neoplasms
Reduced Fhit expression in cervical carcinoma: correlation with tumor progression and poor prognosis.
Neoplasms
Reduced Fhit expression is associated with mismatch repair deficiency in human advanced colorectal carcinoma.
Neoplasms
Reduced Fhit protein expression and loss of heterozygosity at FHIT gene in tumours from smoking and asbestos-exposed lung cancer patients.
Neoplasms
Reduced Fhit protein expression in nickel-transformed mouse cells and in nickel-induced murine sarcomas.
Neoplasms
Reduction in squamous cell carcinomas in mouse skin by dietary zinc supplementation.
Neoplasms
Replicative Stress and the FHIT Gene: Roles in Tumor Suppression, Genome Stability and Prevention of Carcinogenesis.
Neoplasms
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in breast cancer cell lines.
Neoplasms
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in lung and cervical cancer cell lines.
Neoplasms
Restoration of fragile histidine triad expression restores Chk2 activity in response to ionizing radiation in oral squamous cell carcinoma cells.
Neoplasms
Restored expression of fragile histidine triad protein and tumorigenicity of cervical carcinoma cells.
Neoplasms
Simultaneous detection of the tumor suppressor FHIT gene and protein using the multi-functional biochip.
Neoplasms
Specific and nonspecific enzymes involved in the catabolism of mononucleoside and dinucleoside polyphosphates.
Neoplasms
Strong signature of natural selection within an FHIT intron implicated in prostate cancer risk.
Neoplasms
The apoptotic pathway triggered by the Fhit protein in lung cancer cell lines is not affected by Bcl-2 or Bcl-x(L) overexpression.
Neoplasms
The FHIT gene is expressed in pancreatic ductular cells and is altered in pancreatic cancers.
Neoplasms
The fragile histidine triad gene: a molecular link between cigarette smoking and cervical cancer.
Neoplasms
The fragile histidine triad/common chromosome fragile site 3B locus and repair-deficient cancers.
Neoplasms
The role of human papillomavirus type 16 and the fragile histidine triad gene in the outcome of cervical neoplastic lesions.
Neoplasms
The roles of sphingosine kinases 1 and 2 in regulating the Warburg effect in prostate cancer cells.
Neoplasms
The tumor suppressor Fhit acts as a repressor of beta-catenin transcriptional activity.
Neoplasms
Tissue tumor marker expression in smokers, including serum cotinine concentrations, in women with cervical intraepithelial neoplasia or normal squamous cervical epithelium.
Neoplasms
TRAIL-induced apoptosis of FHIT-negative lung cancer cells is inhibited by FHIT re-expression.
Neoplasms
Tumor suppressor Fhit protein interacts with protoporphyrin IX in vitro and enhances the response of HeLa cells to photodynamic therapy.
Neoplasms
Tumor-specific methylation in bronchial lavage for the early detection of non-small-cell lung cancer.
Neoplasms
Two-hit inactivation of FHIT by loss of heterozygosity and hypermethylation in breast cancer.
Neoplasms
Ubc9-induced inhibition of diadenosine triphosphate hydrolase activity of the putative tumor suppressor protein Fhit.
Neoplasms
[Aberrant promoter methylation of tumor suppressor genes in serum from lung cancer patients: frequency and correlation with clinicopathological characteristics]
Neoplasms
[Abnormal expression of fragile histidine triad (FHIT) and Mut S homolog 2 (MSH2) proteins in human sporadic colorectal carcinoma and their clinical significance]
Neoplasms
[Allelic loss and down-regulation of FHIT gene expression in esophageal squamous cell carcinoma]
Neoplasms
[Clinicopathological analysis of loss of fragile histidine triad expression in lung cancer].
Neoplasms
[Correlation between methylation of 5'-CpG islands and inactivation of FHIT gene in cervical cancer.]
Neoplasms
[Correlation of FHIT expression to cell proliferation and metastasis of laryngeal squamous cell carcinoma.]
Neoplasms
[Effects of Methylation of FHIT Gene on it's Protein and mRNA Expression in Non-small Cell Lung Cancer.]
Neoplasms
[Expression of FHIT gene in precancerous lesions and primary lung cancer tissues].
Neoplasms
[HPV detection and FHIT expression in esophageal squamous carcinoma from high incidence area in Cixian County]
Neoplasms
[Methylation status of FHIT gene in plasma and expression of FHIT gene in cancer tissue of cervical cancer patients]
Neoplasms
[Mutations of fragile histidine triad gene in Peutz-Jeghers syndrome and canceration]
Neoplasms
[The biological significance of FHIT protein expression in lung cancer and precancerous tissues detected by tissue microarray.]
Neoplasms, Germ Cell and Embryonal
Alterations of the fragile histidine triad gene, FHIT, and its encoded products contribute to testicular germ cell tumorigenesis.
Neoplasms, Germ Cell and Embryonal
Loss of Fhit expression in testicular germ cell tumors and intratubular germ cell neoplasia.
Neoplasms, Squamous Cell
Reduced acetylated histone H4 is associated with promoter methylation of the fragile histidine triad gene in resected esophageal squamous cell carcinoma.
Odontogenic Cysts
Assessment of fragile histidine triad expression in ameloblastoma, odontogenic keratocyst and dentigerous cyst.
Odontogenic Tumors
Alterations of FHIT and P53 genes in keratocystic odontogenic tumor, dentigerous and radicular cyst.
Oral Submucous Fibrosis
[Expression of FHIT and MDM2 in oral submucous fibrosis and canceration tissues]
Pancreatic Neoplasms
Fragile histidine triad expression delays tumor development and induces apoptosis in human pancreatic cancer.
Pancreatic Neoplasms
The FHIT gene is expressed in pancreatic ductular cells and is altered in pancreatic cancers.
Papillomavirus Infections
Cervical dysplasia, ploidy, and human papillomavirus status correlate with loss of Fhit expression.
Papillomavirus Infections
Frequent epigenetic silencing of the FHIT gene in penile squamous cell carcinomas.
Papillomavirus Infections
[HPV detection and FHIT expression in esophageal squamous carcinoma from high incidence area in Cixian County]
Parathyroid Neoplasms
Expression of Ki-67, galectin-3, fragile histidine triad, and parafibromin in malignant and benign parathyroid tumors.
Peutz-Jeghers Syndrome
[Mutations of fragile histidine triad gene in Peutz-Jeghers syndrome and canceration]
Pleural Effusion
Diagnostic value of the FHIT and p16 mRNA loss and the K-ras gene mutation in pleural fluids for malignant pleural effusion.
Pneumonia
Microsatellite instability and loss of heterozygosity of fragile histidine triad gene in lung hyperplastic lesions.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Clinical significance of fragile histidine triad gene expression in adult acute lymphoblastic leukemia.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
FHIT Gene Expression in Acute Lymphoblastic Leukemia and its Clinical Significance.
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Gene expression of WWOX, FHIT and p73 in acute lymphoblastic leukemia.
Prostatic Neoplasms
Fragile histidine triad gene expression in primary prostate cancer and in an in vitro model.
Prostatic Neoplasms
Strong signature of natural selection within an FHIT intron implicated in prostate cancer risk.
Pulmonary Arterial Hypertension
Fragile Histidine Triad (FHIT), a Novel Modifier Gene in Pulmonary Arterial Hypertension.
Radicular Cyst
Alterations of FHIT and P53 genes in keratocystic odontogenic tumor, dentigerous and radicular cyst.
Retinoblastoma
Altered p16INK4a and Fhit expression in carcinogenesis and progression of human oral cancer.
Retinoblastoma
Comparative analysis of loss of heterozygosity of specific chromosome 3, 13, 17, and X loci and TP53 mutations in human epithelial ovarian cancer.
Retinoblastoma
Loss of heterozygosity on chromosomes 3, 9, 13, and 17, including the retinoblastoma locus, in uveal melanoma.
Sarcoma
Reduced Fhit protein expression in nickel-transformed mouse cells and in nickel-induced murine sarcomas.
Skin Neoplasms
Deletion mapping of chromosome 3p and 13q and preliminary analysis of the FHIT gene in human nonmelanoma skin cancer.
Skin Neoplasms
Reduction in squamous cell carcinomas in mouse skin by dietary zinc supplementation.
Small Cell Lung Carcinoma
Coexpression of fragile histidine triad and c-kit is relevant for prediction of survival in patients with small cell lung cancer.
Small Cell Lung Carcinoma
Prognostic relevance of fragile histidine triad protein expression in patients with small cell lung cancer.
Squamous Cell Carcinoma of Head and Neck
Aberration of FHIT gene is associated with increased tumor proliferation and decreased apoptosis-clinical evidence in lung and head and neck carcinomas.
Squamous Cell Carcinoma of Head and Neck
Abnormalities of the FHIT gene in human oral carcinogenesis.
Squamous Cell Carcinoma of Head and Neck
Altered p16INK4a and Fhit expression in carcinogenesis and progression of human oral cancer.
Squamous Cell Carcinoma of Head and Neck
Analysis of FHIT allelic imbalance/loss of heterozygosity and FHIT expression in cutaneous squamous cell carcinomas.
Squamous Cell Carcinoma of Head and Neck
Clinicopathological significance of the fragile histidine triad transcription protein expression in laryngeal carcinogenesis.
Squamous Cell Carcinoma of Head and Neck
Decreased fragile histidine triad gene protein expression is associated with worse prognosis in oral squamous carcinoma.
Squamous Cell Carcinoma of Head and Neck
Fragile histidine triad expression in oral squamous cell carcinoma and precursor lesions.
Squamous Cell Carcinoma of Head and Neck
Immunohistochemical evaluation of Fhit protein expression in oral squamous cell carcinomas.
Squamous Cell Carcinoma of Head and Neck
Loss of Fhit expression in head and neck squamous cell carcinoma and its potential clinical implication.
Squamous Cell Carcinoma of Head and Neck
Low expression of fragile histidine triad gene correlates with high proliferation in head and neck squamous cell carcinoma.
Squamous Cell Carcinoma of Head and Neck
Microsatellite instability and loss of heterozygosity in oral squamous cell carcinoma in Malaysian population.
Squamous Cell Carcinoma of Head and Neck
Prognostic significance of p53 and FHIT in advanced oropharyngeal carcinoma.
Squamous Cell Carcinoma of Head and Neck
Restoration of fragile histidine triad expression restores Chk2 activity in response to ionizing radiation in oral squamous cell carcinoma cells.
Squamous Cell Carcinoma of Head and Neck
[Expressions of FHIT and cyclin D1/CDK4 in oral cancer and oral precancerous lesions]
Squamous Cell Carcinoma of Head and Neck
[Microsatellite instability and loss of heterozygosity of fragile histidine triad gene in laryngeal squamous cell carcinoma]
Stomach Neoplasms
Abnormal FHIT protein expression may be correlated with poor prognosis in gastric cancer: a meta-analysis.
Stomach Neoplasms
Fhit expression in gastric adenocarcinoma: correlation with disease stage and survival.
Stomach Neoplasms
Fhit protein expression in human gastric cancer and related precancerous lesions.
Stomach Neoplasms
Immunohistochemical expression of Fhit protein in Helicobacter pylori related chronic gastritis, gastric precancerous lesions and gastric carcinoma: correlation with conventional clinicopathologic parameters.
Stomach Neoplasms
Loss of FHIT protein expression correlates with disease progression and poor differentiation in gastric cancer.
Stomach Neoplasms
Prognostic value of EUS combined with MSCT in predicting the recurrence and metastasis of patients with gastric cancer.
Stomach Neoplasms
Relationship between abnormality of FHIT gene and EBV infection in gastric cancer.
Stomach Neoplasms
[Effect of fragile histidine triad gene on apoptosis of MGC-803 gastric cancer cells]
Teratoma
Alterations of the fragile histidine triad gene, FHIT, and its encoded products contribute to testicular germ cell tumorigenesis.
Thyroid Neoplasms
Altered gene expression in immunogenic poorly differentiated thyroid carcinomas from RET/PTC3p53-/- mice.
Thyroid Neoplasms
Association of the promoter methylation and protein expression of Fragile Histidine Triad (FHIT) gene with the progression of differentiated thyroid carcinoma.
Thyroid Neoplasms
Comparative analysis of protein expression in differentiated thyroid tumours: a multicentre study.
Thyroid Neoplasms
Homozygous deletion but not mutation of exons 5 and 8 of the fragile histidine triad (FHIT) gene is associated with features of differentiated thyroid carcinoma.
Urinary Bladder Neoplasms
Homozygous deletion of the FHIT gene, p21WAF1 protein expression and apoptosis in bilharzial bladder cancer.
Urinary Bladder Neoplasms
Prevention of urinary bladder cancer in the FHIT knock-out mouse with Rofecoxib, a Cox-2 inhibitor.
Urinary Bladder Neoplasms
The Clinical Relevance of Fragile Histidine Triad Protein (FHIT) in Patients with Bladder Cancer.
Uterine Cervical Neoplasms
Abnormal Fhit expression is an independent poor prognostic factor for cervical cancer.
Uterine Cervical Neoplasms
Abnormal fragile histidine triad expression in advanced cervical cancer and evaluation of its utility as a prognostic factor.
Uterine Cervical Neoplasms
Abnormalities of fragile histidine triad genomic and complementary DNAs in cervical cancer: association with human papillomavirus type.
Uterine Cervical Neoplasms
Folate deficiency and aberrant DNA methylation and expression of FHIT gene were associated with cervical pathogenesis.
Uterine Cervical Neoplasms
Folate deficiency and FHIT hypermethylation and HPV 16 infection promote cervical cancerization.
Uterine Cervical Neoplasms
Frequent FHIT gene loss of heterozygosity in human papillomavirus-infected non-smoking female lung cancer in Taiwan.
Uterine Cervical Neoplasms
Loss of FHIT expression in cervical carcinoma cell lines and primary tumors.
Uterine Cervical Neoplasms
Methylation status of the fragile histidine triad and E-cadherin genes in plasma of cervical cancer patients.
Uterine Cervical Neoplasms
Reduction in the copy number and expression level of the recurrent human papillomavirus integration gene fragile histidine triad (FHIT) predicts the transition of cervical lesions.
Uterine Cervical Neoplasms
Restoration of fragile histidine triad (FHIT) expression induces apoptosis and suppresses tumorigenicity in lung and cervical cancer cell lines.
Uterine Cervical Neoplasms
Restored expression of fragile histidine triad protein and tumorigenicity of cervical carcinoma cells.
Uterine Cervical Neoplasms
The fragile histidine triad gene: a molecular link between cigarette smoking and cervical cancer.
Uterine Cervical Neoplasms
Understanding the mechanisms of FHIT inactivation in cervical cancer for biomarker development.
Uterine Cervical Neoplasms
[Correlation between methylation of 5'-CpG islands and inactivation of FHIT gene in cervical cancer.]
Uterine Cervical Neoplasms
[Influence of folate on fragile histidine triad gene expression, cell proliferation and apoptosis in cervical cancer cell lines].
Uterine Cervical Neoplasms
[Interaction between folate deficiency and aberrant expression related to fragile histidine triad gene in the progression of cervical cancerization].
Uterine Cervical Neoplasms
[Interaction between fragile histidine triad methylation, protein expression and human papillomavirus 16 infection in cervical carcinogenesis].
Uterine Cervical Neoplasms
[Methylation status of FHIT gene in plasma and expression of FHIT gene in cancer tissue of cervical cancer patients]
von Hippel-Lindau Disease
Allele loss and promoter hypermethylation of VHL, RAR-beta, RASSF1A, and FHIT tumor suppressor genes on chromosome 3p in esophageal squamous cell carcinoma.
von Hippel-Lindau Disease
Hypermethylation and loss of heterozygosity of tumor suppressor genes on chromosome 3p in cervical cancer.
html completed