Reference on EC 3.6.1.27 - undecaprenyl-diphosphate phosphatase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Stone, K.J.; Strominger, J.L.
Mechanism of action of bacitracin: complexation with metal ion and C 55 -isoprenyl pyrophosphate
Proc. Natl. Acad. Sci. USA
68
3223-3227
1971
Enterococcus faecalis
Goldman, R.; Strominger, J.L.
Purification and properties of C 55 -isoprenylpyrophosphate phosphatase from Micrococcus lysodeikticus
J. Biol. Chem.
247
5116-5122
1972
Micrococcus luteus
El Ghachi, M.; Derbise, A.; Bouhss, A.; Mengin-Lecreulx, D.
Identification of multiple genes encoding membrane proteins with undecaprenyl pyrophosphate phosphatase (UppP) activity in Escherichia coli
J. Biol. Chem.
280
18689-18695
2005
Escherichia coli
Bernard, R.; El Ghachi, M.; Mengin-Lecreulx, D.; Chippaux, M.; Denizot, F.
BcrC from Bacillus subtilis acts as an undecaprenyl pyrophosphate phosphatase in bacitracin resistance
J. Biol. Chem.
280
28852-28857
2005
Bacillus subtilis
Touze, T.; Blanot, D.; Mengin-Lecreulx, D.
Substrate specificity and membrane topology of Escherichia coli PgpB, an undecaprenyl pyrophosphate phosphatase
J. Biol. Chem.
283
16573-16583
2008
Escherichia coli
Tatar, L.D.; Marolda, C.L.; Polischuk, A.N.; van Leeuwen, D.; Valvano, M.A.
An Escherichia coli undecaprenyl-pyrophosphate phosphatase implicated in undecaprenyl phosphate recycling
Microbiology
153
2518-2529
2007
Escherichia coli
Hynninen, A.; Touze, T.; Pitkaenen, L.; Mengin-Lecreulx, D.; Virta, M.
An efflux transporter PbrA and a phosphatase PbrB cooperate in a lead-resistance mechanism in bacteria
Mol. Microbiol.
74
384-394
2009
Cupriavidus metallidurans, Cupriavidus metallidurans CH34
Coker, O.; Palittapongarnpim, P.
Current understanding of de novo synthesis of bacterial lipid carrier (undecaprenyl phosphate): More enzymes to be discovered
Afr. J. Microbiol. Res.
5
2555-2565
2011
Escherichia coli (P60932), Bacillus subtilis (P94571)
-
Hashizume, H.; Sawa, R.; Harada, S.; Igarashi, M.; Adachi, H.; Nishimura, Y.; Nomoto, A.
Tripropeptin C blocks the lipid cycle of cell wall biosynthesis by complex formation with undecaprenyl pyrophosphate
Antimicrob. Agents Chemother.
55
3821-3828
2011
Micrococcus luteus (C5CBT8)
Shaaly, A.; Kalamorz, F.; Gebhard, S.; Cook, G.M.
Undecaprenyl pyrophosphate phosphatase confers low-level resistance to bacitracin in Enterococcus faecalis
J. Antimicrob. Chemother.
68
1583-1593
2013
Enterococcus faecalis (Q5WNX2), Enterococcus faecalis
Chang, H.Y.; Chou, C.C.; Hsu, M.F.; Wang, A.H.
Proposed carrier lipid-binding site of undecaprenyl pyrophosphate phosphatase from Escherichia coli
J. Biol. Chem.
289
18719-18735
2014
Escherichia coli (P60932), Escherichia coli
Kawakami, N.; Fujisaki, S.
Undecaprenyl phosphate metabolism in Gram-negative and Gram-positive bacteria
Biosci. Biotechnol. Biochem.
82
940-946
2018
Escherichia coli
Wang, Y.; Desai, J.; Zhang, Y.; Malwal, S.R.; Shin, C.J.; Feng, X.; Sun, H.; Liu, G.; Guo, R.T.; Oldfield, E.
Bacterial cell growth inhibitors targeting undecaprenyl diphosphate synthase and undecaprenyl diphosphate phosphatase
ChemMedChem
11
2311-2319
2016
Escherichia coli
Elsebaei, M.; Mohammad, H.; Samir, A.; Abutaleb, N.; Norvil, A.; Michie, A.; Moustafa, M.; Samy, H.; Gowher, H.; Seleem, M.; Mayhoub, A.
Lipophilic efficient phenylthiazoles with potent undecaprenyl pyrophosphatase inhibitory activity
Eur. J. Med. Chem.
175
49-62
2019
Staphylococcus aureus, Staphylococcus aureus USA 400
Radeck, J.; Lautenschlaeger, N.; Mascher, T.
The essential UPP phosphatase pair BcrC and UppP connects cell wall homeostasis during growth and sporulation with cell envelope stress response in Bacillus subtilis
Front. Microbiol.
8
2403
2017
Bacillus subtilis
Zhao, H.; Sun, Y.; Peters, J.M.; Gross, C.A.; Garner, E.C.; Helmann, J.D.
Depletion of undecaprenyl pyrophosphate phosphatases disrupts cell envelope biogenesis in Bacillus subtilis
J. Bacteriol.
198
2925-2935
2016
Bacillus subtilis
Jalal, N.; Tian, X.L.; Dong, G.; Upham, J.; Chen, C.; Parcells, M.; Li, Y.H.
Identification and characterization of SMU.244 encoding a putative undecaprenyl pyrophosphate phosphatase protein required for cell wall biosynthesis and bacitracin resistance in Streptococcus mutans
Microbiology
161
1857-1870
2015
Streptococcus mutans, Streptococcus mutans WT UA159
El Ghachi, M.; Howe, N.; Huang, C.Y.; Olieric, V.; Warshamanage, R.; Touze, T.; Weichert, D.; Stansfeld, P.J.; Wang, M.; Kerff, F.; Caffrey, M.
Crystal structure of undecaprenyl-pyrophosphate phosphatase and its role in peptidoglycan biosynthesis
Nat. Commun.
9
1078
2018
Escherichia coli (P60932)
Manat, G.; El Ghachi, M.; Auger, R.; Baouche, K.; Olatunji, S.; Kerff, F.; Touze, T.; Mengin-Lecreulx, D.; Bouhss, A.
Membrane topology and biochemical characterization of the Escherichia coli BacA undecaprenyl-pyrophosphate phosphatase
PLoS ONE
10
e0142870
2015
Escherichia coli
Gasiorowski, E.; Auger, R.; Tian, X.; Hicham, S.; Ecobichon, C.; Roure, S.; Douglass, M.V.; Trent, M.S.; Mengin-Lecreulx, D.; Touze, T.; Boneca, I.G.
HupA, the main undecaprenyl pyrophosphate and phosphatidylglycerol phosphate phosphatase in Helicobacter pylori is essential for colonization of the stomach
PLoS Pathog.
15
e1007972
2019
Helicobacter pylori, Helicobacter pylori N6
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