Reference on EC 3.5.3.6 - arginine deiminase
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Shibatani, T.; Kakimoto, T.; Chibata, I.
Crystallization and properties of L-arginine deiminase of Pseudomonas putida
J. Biol. Chem.
250
4580-4583
1975
Pseudomonas putida
Kakimoto, T.; Shibatani, T.; Chibata, I.
Crystallization of L-arginine-deiminase from Pseudomonas putida
FEBS Lett.
19
166-168
1971
Pseudomonas putida
Fenske, J.D.; Kenny, G.E.
Role of arginine deiminase in growth of Mycoplasma hominis
J. Bacteriol.
126
501-510
1976
Mycoplasmopsis arginini, Mycoplasma arthritidis, Mycoplasmopsis fermentans, Mycoplasmopsis gallinarum, Mycoplasma gallisepticum, Mycoplasma hominis, Mycoplasma hominis 14027, Mycoplasmopsis arginini G230, Mycoplasmopsis arginini 67-166
Weickmann, J.L.; Fahrney, D.E.
Arginine deiminase from Mycoplasma arthritidis. Evidence for multiple forms
J. Biol. Chem.
252
2615-2620
1977
Mycoplasma arthritidis
Smith, D.W.; Fahrney, D.E.
Catalysis by arginine deiminase: evidence for a covalent intermediate
Biochem. Biophys. Res. Commun.
83
101-106
1978
Mycoplasma arthritidis
Weickmann, J.L.; Himmel, M.E.; Smith, D.W.; Fahrney, D.E.
Arginine deiminase: demonstration of two active sites and possible half-of-the-sites reactivity
Biochem. Biophys. Res. Commun.
83
107-113
1978
Mycoplasma arthritidis
Weickmann, J.L.; Himmel, M.E.; Squire, P.G.; Fahrney, D.E.
Arginine deiminase from Mycoplasma arthritidis. Properties of the enzyme from log phase cultures
J. Biol. Chem.
253
6010-6015
1978
Mycoplasma arthritidis
Smith, D.W.; Ganaway, R.L.; Fahrney, D.E.
Arginine deiminase from Mycoplasma arthritidis. Structure-activity relationships among substrates and competitive inhibitors
J. Biol. Chem.
253
6016-6020
1978
Mycoplasma arthritidis
Shibatani, T.; Kakimoto, T.; Chibata, I.
Subunit and amino acid composition of L-arginine deiminase of Pseudomonas putida
FEBS Lett.
96
389-391
1978
Pseudomonas putida
Park, B.S.; Hirotani, A.; Nakano, Y.; Kitaoka, S.
Purification and some properties of arginine deiminase in Euglena gracilis Z
Agric. Biol. Chem.
48
483-489
1984
Euglena gracilis
-
Manca de Nadra, M.C.; Pesce de Ruiz Holgado, A.A.; Oliver, G.
Isolation and properties of arginine deiminase in Lactobacillus buchneri NCDO110
J. Appl. Biochem.
6
184-187
1984
Lentilactobacillus buchneri, Lentilactobacillus buchneri NCDO110
-
Sacks, L.E.
Increased formation of arginine deiminase by Clostridium perfringens FD-1 growing in the presence of caffeine
Experientia
41
1435-1437
1984
Clostridium perfringens, Clostridium perfringens FD-1
Lin, J.S.L.
Arginine deiminase of Mycoplasma hominis: cytoplasmic and membrane-associated forms
J. Gen. Microbiol.
132
1467-1474
1986
Mycoplasma hominis
Hiraoka, B.Y.; Harada, M.; Fukasawa, K.; Mogi, M.
Intracellular localization of the arginine deiminase pathway in Streptococcus mitis
Curr. Microbiol.
15
81-84
1987
Streptococcus mitis
-
Knodler, L.A.; Sekyere, E.O.; Stewart, T.S.; Schofield, P.J.; Edwards, M.R.
Cloning and expression of a prokaryotic enzyme, arginine deiminase, from primitive eukaryote Giardia intestinalis
J. Biol. Chem.
273
4470-4477
1998
Giardia intestinalis (Q27657), Giardia intestinalis
Komada, Y.; Zhang, X.L.; Zhou, Y.W.; Ido, M.; Azuma, E.
Apoptotic cell death of human T lymphoblastoid cells induced by arginine deiminase
Int. J. Hematol.
65
129-141
1997
Mycoplasmopsis arginini
Kang, S.W.; Kang, H.; Park, I.S.; Choi, S.H.; Shin, K.H.; Chun, Y.S.; Chun, G.B.; Min, B.H.
Cytoprotective effect of arginine deiminase on taxol-induced apoptosis in DU145 human prostate cancer cells
Mol. Cells
10
331-337
2000
Mycoplasmopsis arginini
Liu, S.Q.; Pritchard, G.G.; Hardman, M.J.; Pilone, G.J.
Occurrence of arginine deiminase pathway enzymes in arginine catabolism by wine lactic acid bacteria
Appl. Environ. Microbiol.
61
310-316
1995
Levilactobacillus brevis, Lentilactobacillus buchneri, Lentilactobacillus hilgardii, Oenococcus oeni, no activity in Lactobacillus brevis, no activity in Lactobacillus delbrueckii, no activity in Lactobacillus plantarum, no activity in Oenococcus oeni, no activity in Pediococcus sp., Oenococcus oeni MCW, Oenococcus oeni Microenos B2, Oenococcus oeni Microoenos B, Oenococcus oeni DSIR-C, Oenococcus oeni DSIR-B, Oenococcus oeni DSIR-A, Lentilactobacillus hilgardii Microenos HP, Oenococcus oeni OENO, Levilactobacillus brevis EQUILAIT, Oenococcus oeni L181, Oenococcus oeni Er1a, Oenococcus oeni 252, Oenococcus oeni 1008, Oenococcus oeni 2043, Oenococcus oeni ML34, no activity in Lactobacillus delbrueckii CUC-1, no activity in Lactobacillus brevis ML30, Oenococcus oeni 122, Levilactobacillus brevis 250, Oenococcus oeni PSU-1, Oenococcus oeni Vinoflora Oenos, Oenococcus oeni Ey2d, Lentilactobacillus buchneri CUC-3, Oenococcus oeni 2035
Yarlett, N.; Martinez, M.P.; Moharrami, M.A.; Tachezy, J.
The contribution of the arginine dihydrolase pathway to energy metabolism by Trichomonas vaginalis
Mol. Biochem. Parasitol.
78
117-125
1996
Trichomonas vaginalis
Monstadt, G.M.; Holldorf, A.W.
Arginine deiminase from Halobacterium salinarium. Purification and properties
Biochem. J.
273
739-745
1990
Halobacterium salinarum
-
Takaku, H.; Takase, M.; Abe, S.i.; Hayashi, H.; Miyazaki, K.
In vivo anti-tumor activity of arginine deiminase purified from Mycoplasma arginini
Int. J. Cancer
51
244-249
1992
Mycoplasmopsis arginini, Pseudomonas putida
Sugimura, K.; Fukuda, S.; Wada, Y.; Taniai, M.; Suzuki, M.; Kimura, T.; Ohno, T.; Yamamoto, K.; Azuma, I.
Identification and purification of arginine deiminase that originated from Mycoplasma arginini
Infect. Immun.
58
2510-2515
1990
Mycoplasmopsis arginini
Degnan, B.A.; Palmer, J.M.; Robson, T.; Jones, C.E.D.; Fischer, M.; Glanville, M.; Mellor, G.D.; Diamond, A.G.; Kehoe, M.A.; Goodacre, J.A.
Inhibition of human peripheral blood mononuclear cell proliferation by Streptococcus pyogenes cell extract is associated with arginine deiminase activity
Infect. Immun.
66
3050-3058
1998
Mycoplasmopsis arginini, Streptococcus pyogenes
Schofield, P.J.; Costello, M.; Edwards, M.R.; OSullivan, W.J.
The arginine dihydrolase pathway is present in Giardia intestinalis
Int. J. Parasitol.
20
697-699
1990
Giardia intestinalis
Misawa, S.; Aoshima, M.; Takaku, H.; Matsumoto, M.; Hayashi, H.
High-level expression of Mycoplasma arginine deiminase in Escherichia coli and its efficient renaturation as an anti-tumor enzyme
J. Biotechnol.
36
145-155
1994
Mycoplasmopsis arginini
Gong, H.; Zoelzer, F.; von Recklinghausen, G.; Havers, W.; Schweigerer, L.
Arginine deiminase inhibits proliferation of human leukemia cells more potently than asparaginase by inducing cell cycle arrest and apoptosis
Leukemia
14
826-829
2000
Mycoplasmopsis arginini
Oudjama, Y.; Tricot, C.; Stalon, V.; Wouters, J.
Overexpression, purification, crystallization and preliminary X-ray crystallographic analysis of Pseudomonas aeruginosa L-arginine deiminase
Acta Crystallogr. Sect. D
58
2150-2152
2002
Pseudomonas aeruginosa
Lu, X.; Galkin, A.; Herzberg, O.; Dunaway-Mariano, D.
Arginine deiminase uses an active-site cysteine in nucleophilic catalysis of L-arginine hydrolysis
J. Am. Chem. Soc.
126
5374-5375
2004
Pseudomonas aeruginosa
Galkin, A.; Kulakova, L.; Sarikaya, E.; Lim, K.; Howard, A.; Herzberg, O.
Structural insight into arginine degradation by arginine deiminase, an antibacterial and parasite drug target
J. Biol. Chem.
279
14001-14008
2004
Pseudomonas aeruginosa
Das, K.; Butler, G.H.; Kwiatkowski, V.; Clark, A.D., Jr.; Yadav, P.; Arnold, E.
Crystal structures of arginine deiminase with covalent reaction intermediates; implications for catalytic mechanism
Structure
12
657-667
2004
Mycoplasmopsis arginini (P23793), Mycoplasmopsis arginini
Lu, X.; Li, L.; Wu, R.; Feng, X.; Li, Z.; Yang, H.; Wang, C.; Guo, H.; Galkin, A.; Herzberg, O.; Mariano, P.S.; Martin, B.M.; Dunaway-Mariano, D.
Kinetic analysis of Pseudomonas aeruginosa arginine deiminase mutants and alternate substrates provides insight into structural determinants of function
Biochemistry
45
1162-1172
2006
Pseudomonas aeruginosa, Pseudomonas aeruginosa (P13981)
Budin-Verneuil, A.; Maguin, E.; Auffray, Y.; Ehrlich, D.S.; Pichereau, V.
Genetic structure and transcriptional analysis of the arginine deiminase (ADI) cluster in Lactococcus lactis MG1363
Can. J. Microbiol.
52
617-622
2006
Lactococcus lactis
Lu, X.; Li, L.; Feng, X.; Wu, Y.; Dunaway-Mariano, D.; Engen, J.R.; Mariano, P.S.
L-Canavanine is a time-controlled mechanism-based inhibitor of Pseudomonas aeruginosa arginine deiminase
J. Am. Chem. Soc.
127
16412-16413
2005
Pseudomonas aeruginosa
Gruening, P.; Fulde, M.; Valentin-Weigand, P.; Goethe, R.
Structure, regulation, and putative function of the arginine deiminase system of Streptococcus suis
J. Bacteriol.
188
361-369
2006
Streptococcus suis
Kubo, M.; Nishitsuji, H.; Kurihara, K.; Hayashi, T.; Masuda, T.; Kannagi, M.
Suppression of human immunodeficiency virus type 1 replication by arginine deiminase of Mycoplasma arginini
J. Gen. Virol.
87
1589-1593
2006
Mycoplasmopsis arginini
Nehme, B.; Ganga, M.A.; Lonvaud-Funel, A.
The arginine deiminase locus of Oenococcus oeni includes a putative arginyl-tRNA synthetase ArgS2 at its 3-end
Appl. Microbiol. Biotechnol.
70
590-597
2006
Oenococcus oeni, Oenococcus oeni IOEB 8406
Galkin, A.; Lu, X.; Dunaway-Mariano, D.; Herzberg, O.
Crystal structures representing the Michaelis complex and the thiouronium reaction intermediate of Pseudomonas aeruginosa arginine deiminase
J. Biol. Chem.
280
34080-34087
2005
Pseudomonas aeruginosa (P13981), Pseudomonas aeruginosa
Spano, G.; Massa, S.; Arena, M.E.; Manca de Nadra, M.C.
Arginine metabolism in wine Lactobacillus plantarum: in vitro activities of the enzymes arginine deiminase (ADI) and ornithine transcarbamilase (OTCase).
Ann. Microbiol.
57
67-70
2007
Lactiplantibacillus plantarum
Wang, M.; Basu, A.; Palm, T.; Hua, J.; Youngster, S.; Hwang, L.; Liu, H.C.; Li, X.; Peng, P.; Zhang, Y.; Zhao, H.; Zhang, Z.; Longley, C.; Mehlig, M.; Borowski, V.; Sai, P.; Viswanathan, M.; Jang, E.; Petti, G.; Liu, S.; Yang, K.; Filpula, D.
Engineering an arginine catabolizing bioconjugate: Biochemical and pharmacological characterization of PEGylated derivatives of arginine deiminase from Mycoplasma arthritidis
Bioconjug. Chem.
17
1447-1459
2006
Mycoplasma arthritidis
Ni, Y.; Schwaneberg, U.; Sun, Z.
Arginine deiminase, a potential anti-tumor drug
Cancer Lett.
261
1-11
2008
Giardia intestinalis, Halobacterium salinarum, Homo sapiens, Lactococcus lactis ssp. lactis, Mycoplasmopsis arginini, Mycoplasma hominis, Pseudomonas aeruginosa, Pseudomonas putida, Streptococcus sanguinis, Pseudomonas plecoglossicida (A7LKB0), Pseudomonas plecoglossicida CGMCC 2039 (A7LKB0)
Feun, L.; Savaraj, N.
Pegylated arginine deiminase: a novel anticancer enzyme agent
Expert Opin. Investig. Drugs
15
815-822
2006
Mycoplasma hominis
Li, L.; Li, Z.; Chen, D.; Lu, X.; Feng, X.; Wright, E.C.; Solberg, N.O.; Dunaway-Mariano, D.; Mariano, P.S.; Galkin, A.; Kulakova, L.; Herzberg, O.; Green-Church, K.B.; Zhang, L.
Inactivation of microbial arginine deiminases by L-canavanine
J. Am. Chem. Soc.
130
1918-1931
2008
Bacillus cereus, Burkholderia mallei, Escherichia coli, Giardia intestinalis, Pseudomonas aeruginosa, Pseudomonas aeruginosa (P13981)
Louw, C.; Gordon, A.; Johnston, N.; Mollatt, C.; Bradley, G.; Whiteley, C.G.
Arginine deiminases: therapeutic tools in the etiology and pathogenesis of Alzheimers disease
J. Enzyme Inhib. Med. Chem.
22
121-126
2007
Pseudomonas aeruginosa
Izzo, F.; Montella, M.; Orlando, A.P.; Nasti, G.; Beneduce, G.; Castello, G.; Cremona, F.; Ensor, C.M.; Holtzberg, F.W.; Bomalaski, J.S.; Clark, M.A.; Curley, S.A.; Orlando, R.; Scordino, F.; Korba, B.E.
Pegylated arginine deiminase lowers hepatitis C viral titers and inhibits nitric oxide synthesis
J. Gastroenterol. Hepatol.
22
86-91
2007
Homo sapiens
Park, H.; Lee, J.B.; Shim, Y.J.; Shin, Y.J.; Jeong, S.Y.; Oh, J.; Park, G.H.; Lee, K.H.; Min, B.H.
Arginine deiminase enhances MCF-7 cell radiosensitivity by inducing changes in the expression of cell cycle-related proteins
Mol. Cells
25
305-311
2008
Mycoplasmopsis arginini
Kim, J.H.; Kim, J.H.; Yu, Y.S.; Kim, D.H.; Min, B.H.; Kim, K.W.
Anti-tumor activity of arginine deiminase via arginine deprivation in retinoblastoma
Oncol. Rep.
18
1373-1377
2007
Homo sapiens
Kim, J.E.; Jeong, D.W.; Lee, H.J.
Expression, purification, and characterization of arginine deiminase from Lactococcus lactis ssp. lactis ATCC 7962 in Escherichia coli BL21
Protein Expr. Purif.
53
9-15
2007
Lactococcus lactis subsp. lactis (Q2HYA0)
Wei, Y.; Zhou, H.; Sun, Y.; He, Y.; Luo, Y.
Insight into the catalytic mechanism of arginine deiminase: functional studies on the crucial sites
Proteins
66
740-750
2007
Mycoplasma hominis
Bowles, T.L.; Kim, R.; Galante, J.; Parsons, C.M.; Virudachalam, S.; Kung, H.J.; Bold, R.J.
Pancreatic cancer cell lines deficient in argininosuccinate synthetase are sensitive to arginine deprivation by arginine deiminase
Int. J. Cancer
123
1950-1955
2008
Homo sapiens
Liu, Y.; Dong, Y.; Chen, Y.Y.; Burne, R.A.
Environmental and growth phase regulation of the Streptococcus gordonii arginine deiminase genes
Appl. Environ. Microbiol.
74
5023-5030
2008
Streptococcus gordonii
Li, L.; Li, Z.; Wang, C.; Xu, D.; Mariano, P.S.; Guo, H.; Dunaway-Mariano, D.
The electrostatic driving force for nucleophilic catalysis in L-arginine deiminase: a combined experimental and theoretical study
Biochemistry
47
4721-4732
2008
Bacillus cereus, Burkholderia mallei, Escherichia coli, Pseudomonas aeruginosa (P13981)
Ni, Y.; Li, Z.; Sun, Z.; Zheng, P.; Liu, Y.; Zhu, L.; Schwaneberg, U.
Expression of arginine deiminase from Pseudomonas plecoglossicida CGMCC2039 in Escherichia coli and its anti-tumor activity
Curr. Microbiol.
58
593-598
2009
Pseudomonas plecoglossicida (A7LKB0), Pseudomonas plecoglossicida, Pseudomonas plecoglossicida CGMCC2039 (A7LKB0)
Ryan, S.; Begley, M.; Gahan, C.G.; Hill, C.
Molecular characterization of the arginine deiminase system in Listeria monocytogenes: regulation and role in acid tolerance
Environ. Microbiol.
11
432-445
2009
Listeria monocytogenes
Lafay, B.; Ruimy, R.; de Traubenberg, C.R.; Breittmayer, V.; Gauthier, M.J.; Christen, R.
Roseobacter algicola sp. nov., a new marine bacterium isolated from the phycosphere of the toxin-producing dinoflagellate Prorocentrum lima
Int. J. Syst. Bacteriol.
45
290-296
1995
no activity in Marinovum algicola, no activity in Marinovum algicola ATCC 51442
Ruiz-Ponte, C.; Cilia, V.; Lambert, C.; Nicolas, J.L.
Roseobacter gallaeciensis sp. nov., a new marine bacterium isolated from rearings and collectors of the scallop Pecten maximus
Int. J. Syst. Bacteriol.
48 Pt 2
537-542
1998
no activity in Phaeobacter gallaeciensis BS107
Lau, S.C.; Tsoi, M.M.; Li, X.; Plakhotnikova, I.; Wu, M.; Wong, P.K.; Qian, P.Y.
Loktanella hongkongensis sp. nov., a novel member of the alpha-Proteobacteria originating from marine biofilms in Hong Kong waters
Int. J. Syst. Evol. Microbiol.
54
2281-2284
2004
no activity in Loktanella hongkongensis
Lin, X.; Lamont, R.J.; Wu, J.; Xie, H.
Role of differential expression of streptococcal arginine deiminase in inhibition of fimA expression in Porphyromonas gingivalis
J. Bacteriol.
190
4367-4371
2008
Streptococcus cristatus, Streptococcus cristatus CC5A
Yu, H.H.; Wu, F.L.; Lin, S.E.; Shen, L.J.
Recombinant arginine deiminase reduces inducible nitric oxide synthase iNOS-mediated neurotoxicity in a coculture of neurons and microglia
J. Neurosci. Res.
86
2963-2972
2008
Homo sapiens
Rodriguez, S.B.; Stitt, B.L.; Ash, D.E.
Expression of peptidylarginine deiminase from Porphyromonas gingivalis in Escherichia coli: enzyme purification and characterization
Arch. Biochem. Biophys.
488
14-22
2009
Porphyromonas gingivalis, Porphyromonas gingivalis BAA-308-5 (W83)
Li, Z.; Kulakova, L.; Li, L.; Galkin, A.; Zhao, Z.; Nash, T.E.; Mariano, P.S.; Herzberg, O.; Dunaway-Mariano, D.
Mechanisms of catalysis and inhibition operative in the arginine deiminase from the human pathogen Giardia lamblia
Bioorg. Chem.
37
149-161
2009
Giardia intestinalis (Q27657), Giardia intestinalis, Giardia intestinalis isolate WB, clone 1267 (Q27657)
Kim, J.E.; Kim, S.Y.; Lee, K.W.; Lee, H.J.
Arginine deiminase originating from Lactococcus lactis ssp. lactis American Type Culture Collection (ATCC) 7962 induces G1-phase cell-cycle arrest and apoptosis in SNU-1 stomach adenocarcinoma cells
Br. J. Nutr.
102
1469-1476
2009
Lactococcus lactis subsp. lactis (Q2HYA0), Lactococcus lactis subsp. lactis ATCC 7962 (Q2HYA0)
Zhu, L.; Tee, K.L.; Roccatano, D.; Sonmez, B.; Ni, Y.; Sun, Z.H.; Schwaneberg, U.
Directed evolution of an antitumor drug (arginine deiminase PpADI) for increased activity at physiological pH
ChemBioChem
11
691-697
2010
Pseudomonas plecoglossicida
Pereira, C.I.; San Romao, M.V.; Lolkema, J.S.; Crespo, M.T.
Weissella halotolerans W22 combines arginine deiminase and ornithine decarboxylation pathways and converts arginine to putrescine
J. Appl. Microbiol.
107
1894-1902
2009
Weissella halotolerans, Weissella halotolerans W22
Glazer, E.S.; Piccirillo, M.; Albino, V.; Di Giacomo, R.; Palaia, R.; Mastro, A.A.; Beneduce, G.; Castello, G.; De Rosa, V.; Petrillo, A.; Ascierto, P.A.; Curley, S.A.; Izzo, F.
Phase II study of pegylated arginine deiminase for nonresectable and metastatic hepatocellular carcinoma
J. Clin. Oncol.
28
2220-2226
2010
Mycoplasma sp.
Rimaux, T.; Riviere, A.; Illeghems, K.; Weckx, S.; De Vuyst, L.; Leroy, F.
Expression of the arginine deiminase pathway genes in Lactobacillus sakei is strain dependent and is affected by the environmental pH
Appl. Environ. Microbiol.
78
4874-4883
2012
Latilactobacillus sakei
Ni, Y.; Liu, Y.; Schwaneberg, U.; Zhu, L.; Li, N.; Li, L.; Sun, Z.
Rapid evolution of arginine deiminase for improved anti-tumor activity
Appl. Microbiol. Biotechnol.
90
193-201
2011
Pseudomonas plecoglossicida
Zhuo, W.; Song, X.; Zhou, H.; Luo, Y.
Arginine deiminase modulates endothelial tip cells via excessive synthesis of reactive oxygen species
Biochem. Soc. Trans.
39
1376-1381
2011
Homo sapiens
Kelly, M.P.; Jungbluth, A.A.; Wu, B.W.; Bomalaski, J.; Old, L.J.; Ritter, G.
Arginine deiminase PEG20 inhibits growth of small cell lung cancers lacking expression of argininosuccinate synthetase
Br. J. Cancer
106
324-332
2012
Homo sapiens
Rimaux, T.; Vrancken, G.; Pothakos, V.; Maes, D.; De Vuyst, L.; Leroy, F.
The kinetics of the arginine deiminase pathway in the meat starter culture Lactobacillus sakei CTC 494 are pH-dependent
Food Microbiol.
28
597-604
2011
Latilactobacillus sakei
Chantratita, N.; Tandhavanant, S.; Wikraiphat, C.; Trunck, L.A.; Rholl, D.A.; Thanwisai, A.; Saiprom, N.; Limmathurotsakul, D.; Korbsrisate, S.; Day, N.P.; Schweizer, H.P.; Peacock, S.J.
Proteomic analysis of colony morphology variants of Burkholderia pseudomallei defines a role for the arginine deiminase system in bacterial survival
J. Proteomics
75
1031-1042
2012
Burkholderia pseudomallei
Gallego, P.; Planell, R.; Benach, J.; Querol, E.; Perez-Pons, J.A.; Reverter, D.
Structural characterization of the enzymes composing the arginine deiminase pathway in Mycoplasma penetrans
PLoS ONE
7
e47886
2012
Malacoplasma penetrans (Q8EVF6), Malacoplasma penetrans HF-2 (Q8EVF6)
Hering, S.; Sieg, A.; Kreikemeyer, B.; Fiedler, T.
Kinetic characterization of arginine deiminase and carbamate kinase from Streptococcus pyogenes M49
Protein Expr. Purif.
91
61-68
2013
Streptococcus pyogenes (B5XMC3), Streptococcus pyogenes
Slade, D.J.; Fang, P.; Dreyton, C.J.; Zhang, Y.; Fuhrmann, J.; Rempel, D.; Bax, B.D.; Coonrod, S.A.; Lewis, H.D.; Guo, M.; Gross, M.L.; Thompson, P.R.
Protein arginine deiminase 2 binds calcium in an ordered fashion implications for inhibitor design
ACS Chem. Biol.
10
1043-1053
2015
Homo sapiens (Q9Y2J8)
Jamil, S.; Liu, M.H.; Liu, Y.M.; Han, R.Z.; Xu, G.C.; Ni, Y.
Hydrophobic mutagenesis and semi-rational engineering of arginine deiminase for markedly enhanced stability and catalytic efficiency
Appl. Biochem. Biotechnol.
176
1335-1350
2015
Pseudomonas plecoglossicida (A7LKB0), Pseudomonas plecoglossicida, Pseudomonas plecoglossicida CGMCC2039 (A7LKB0)
Cheng, F.; Zhu, L.; Lue, H.; Bernhagen, J.; Schwaneberg, U.
Directed arginine deiminase evolution for efficient inhibition of arginine-auxotrophic melanomas
Appl. Microbiol. Biotechnol.
99
1237-1247
2015
Pseudomonas plecoglossicida (A7LKB0), Pseudomonas plecoglossicida
Starikova, E.A.; Sokolov, A.V.; Vlasenko, A.Y.; Burova, L.A.; Freidlin, I.S.; Vasilyev, V.B.
Biochemical and biological activity of arginine deiminase from Streptococcus pyogenes M22
Biochem. Cell Biol.
94
129-137
2016
Streptococcus pyogenes, Streptococcus pyogenes M22
El-Sayed, A.; Hassan, M.; Nada, H.
Purification, immobilization, and biochemical characterization of L-arginine deiminase from thermophilic Aspergillus fumigatus KJ434941 Anticancer activity in vitro
Biotechnol. Prog.
31
396-405
2015
Aspergillus fumigatus, Aspergillus fumigatus KJ434941
Xiong, L.; Teng, J.L.; Watt, R.M.; Liu, C.; Lau, S.K.; Woo, P.C.
Molecular characterization of arginine deiminase pathway in Laribacter hongkongensis and unique regulation of arginine catabolism and anabolism by multiple environmental stresses
Environ. Microbiol.
17
4469-4483
2015
Laribacter hongkongensis (C1DD78), Laribacter hongkongensis (C1DD83), Laribacter hongkongensis, Laribacter hongkongensis HLHK9 (C1DD78), Laribacter hongkongensis HLHK9 (C1DD83)
El-Sayed, A.; Shindia, A.; Zeid, A.; Yassin, A.; Sitohy, M.; Sitohy, B.
Aspergillus nidulans thermostable arginine deiminase-Dextran conjugates with enhanced molecular stability, proteolytic resistance, pharmacokinetic properties and anticancer activity
Enzyme Microb. Technol.
131
109432
2019
Aspergillus nidulans
Cai, X.; Jiang, H.; Zhang, T.; Jiang, B.; Mu, W.; Miao, M.
Thermostability and specific-activity enhancement of an arginine deiminase from Enterococcus faecalis SK23.001 via semirational design for L-citrulline production
J. Agric. Food Chem.
66
8841-8850
2018
Enterococcus faecalis (A0A3G2YMH7), Enterococcus faecalis, Enterococcus faecalis SK23.001 (A0A3G2YMH7)
Trejo-Soto, P.J.; Aguayo-Ortiz, R.; Yepez-Mulia, L.; Hernandez-Campos, A.; Medina-Franco, J.L.; Castillo, R.
Insights into the structure and inhibition of Giardia intestinalis arginine deiminase homology modeling, docking, and molecular dynamics studies
J. Biomol. Struct. Dyn.
34
732-748
2016
Giardia intestinalis (Q27657), Giardia intestinalis
Patil, M.D.; Rathod, V.P.; Bihade, U.R.; Banerjee, U.C.
Purification and characterization of arginine deiminase from Pseudomonas putida Structural insights of the differential affinities of L-arginine analogues
J. Biosci. Bioeng.
127
129-137
2019
Pseudomonas putida (Q88P52), Pseudomonas putida, Pseudomonas putida ATCC 47054 (Q88P52)
Subramanian, V.; Knight, J.S.; Parelkar, S.; Anguish, L.; Coonrod, S.A.; Kaplan, M.J.; Thompson, P.R.
Design, synthesis, and biological evaluation of tetrazole analogs of Cl-amidine as protein arginine deiminase inhibitors
J. Med. Chem.
58
1337-1344
2015
Homo sapiens (Q9Y2J8)
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