Reference on EC 3.5.3.11 - agmatinase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Friedrich, B.; Magasanik, B.
Enzymes of agmatine degradation and the control of their synthesis in Klebsiella aerogenes
J. Bacteriol.
137
1127-1133
1979
Klebsiella aerogenes
Boldt, A.; Miersch, J.; Reinbothe, H.
Metabolism of agmatine in fruit-bodies of the fungus Panus tigrinus (bull. ex. fr.) sing.
Phytochemistry
10
731-738
1971
Lentinus tigrinus
-
Carvajal, N.; Olate, J.; Salas, M.; Lopez, V.; Cerpa, J.; Herrera, P.; Uribe, E.
Evidence that histidine-163 is critical for catalytic activity, but not for substrate binding to Escherichia coli agmatinase
Biochem. Biophys. Res. Commun.
264
196-200
1999
Escherichia coli
Vicente, C.; Legaz, M.E.
Purification and properties of agmatine amidinohydrolase of Evernia prunastri
Physiol. Plant.
55
335-339
1982
Evernia prunastri
-
Legaz, M.E.; Vicente, C.
Endogenous inactivators of arginase, L-arginine decarboxylase, and agmatine amidinohydrolase in Evernia prunastri thallus
Plant Physiol.
71
300-302
1983
Evernia prunastri
White Tabor, C.; Tabor, H.; Hafner, E.W.; Markham, G.D.; Boyle, S.M.
Cloning of the Escherichia coli genes for the biosynthetic enzymes fo polyamines
Methods Enzymol.
94
117-121
1983
Escherichia coli
Shaibe, E.; Metzer, E.; Halpern, Y.S.
Metabolic pathway for the utilization of L-arginine, L-ornithine, agmatine, and putrescine as nitrogen sources in Escherichia coli K-12
J. Bacteriol.
163
933-937
1985
Escherichia coli
Satishchandran, C.; Boyle S.M.
Purification and properties of agmatine ureohydrolase, a putrescine biosynthetic enzyme in Escherichia coli
J. Bacteriol.
165
843-848
1986
Escherichia coli
Sastre, M.; Regunathan, S.; Galea, E.; Reis, D.J.
Agmatinase activity in rat brain: a metabolic pathway for the degradation of agmatine
J. Neurochem.
67
1761-1765
1995
Rattus norvegicus
Szumanski, M.B.W.; Boyle, S.M.
Influence of cyclic AMP, agmatine and a novel protein encoded by a flanking gene on speB (agmatine ureohydrolase) in Escherichia coli
J. Bacteriol.
174
758-764
1992
Escherichia coli
Szumanski, M.B.W.; Boyle, S.M.
Analysis and sequence of the speB gene encoding agmatine ureohydrolase, a putrescine biosynthetic enzyme in Escherichia coli
J. Bacteriol.
172
538-547
1990
Escherichia coli
Carvajal, N.; Lopez, V.; Salas, M.; Uribe, E.; Herrera, P.; Cerpa, J.
Manganese is essential for catalytic activity of Escherichia coli Agmatinase
Biochem. Biophys. Res. Commun.
258
808-811
1999
Escherichia coli
Carvajal, N.; Orellana, M.S.; Salas, M.; Enriquez, P.; Alarcon, R.; Uribe, E.; Lopez, V.
Kinetic studies and site-directed mutagenesis of Escherichia coli agmatinase. A role for Glu274 in binding and correct positioning of the substrate guanidinium group
Arch. Biochem. Biophys.
430
185-190
2004
Escherichia coli
Salas, M.; Rodriguez, R.; Lopez, N.; Uribe, E.; Lopez, V.; Carvajal, N.
Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling
Eur. J. Biochem.
269
5522-5526
2002
Escherichia coli
Lee, J.A.; Ahn, H.J.; Ha, J.Y.; Shim, S.M.; Kim, K.H.; Kim, H.K.; Suh, S.W.
Crystallization and preliminary X-ray crystallographic analysis of a putative agmatinase from Deinococcus radiodurans
Acta Crystallogr. Sect. D
60
1890-1892
2004
Deinococcus radiodurans
Kim, K.H.; Ahn, H.J.; Kim, D.J.; Lee, H.H.; Ha, J.Y.; Kim, H.K.; Yoon, H.J.; Suh, S.W.
Expression, crystallization and preliminary X-ray crystallographic analysis of human agmatinase
Acta Crystallogr. Sect. F
61
889-891
2005
Homo sapiens
Goda, S.; Sakuraba, H.; Kawarabayasi, Y.; Ohshima, T.
The first archaeal agmatinase from anaerobic hyperthermophilic archaeon Pyrococcus horikoshii: cloning, expression, and characterization
Biochim. Biophys. Acta
1748
110-115
2005
Pyrococcus horikoshii
Dallmann, K.; Junker, H.; Balabanov, S.; Zimmermann, U.; Giebel, J.; Walther, R.
Human agmatinase is diminished in the clear cell type of renal cell carcinoma
Int. J. Cancer
108
342-347
2004
Homo sapiens
Ahn, H.J.; Kim, K.H.; Lee, J.; Ha, J.Y.; Lee, H.H.; Kim, D.; Yoon, H.J.; Kwon, A.R.; Suh, S.W.
Crystal structure of agmatinase reveals structural conservation and inhibition mechanism of the ureohydrolase superfamily
J. Biol. Chem.
279
50505-50513
2004
Deinococcus radiodurans
Salas, M.; Lopez, V.; Uribe, E.; Carvajal, N.
Studies on the interaction of Escherichia coli agmatinase with manganese ions: structural and kinetic studies of the H126N and H151N variants
J. Inorg. Biochem.
98
1032-1036
2004
Escherichia coli
Alarcon, R.; Orellana, M.S.; Neira, B.; Uribe, E.; Garcia, J.R.; Carvajal, N.
Mutational analysis of substrate recognition by human arginase type I -agmatinase activity of the N130D variant
FEBS J.
273
5625-5631
2006
Homo sapiens
Haenisch, B.; von Kuegelgen, I.; Boenisch, H.; Goethert, M.; Sauerbruch, T.; Schepke, M.; Marklein, G.; Hoefling, K.; Schroeder, D.; Molderings, G.J.
Regulatory mechanisms underlying agmatine homeostasis in humans
Am. J. Physiol. Gastrointest. Liver Physiol.
295
G1104-G1110
2008
Homo sapiens (Q9BSE5), Homo sapiens
Bernstein, H.G.; Derst, C.; Stich, C.; Pruess, H.; Peters, D.; Krauss, M.; Bogerts, B.; Veh, R.W.; Laube, G.
The agmatine-degrading enzyme agmatinase: a key to agmatine signaling in rat and human brain?
Amino Acids
40
453-465
2010
Homo sapiens, Rattus norvegicus
Mella, C.; Martinez, F.; de Los Angeles Garcia, M.; Nualart, F.; Castro, V.; Bustos, P.; Carvajal, N.; Uribe, E.
Expression and localization of an agmatinase-like protein in the rat brain
Histochem. Cell Biol.
134
137-144
2010
Rattus norvegicus
Chattopadhyay, M.K.; Tabor, C.W.; Tabor, H.
Polyamines are not required for aerobic growth of Escherichia coli: preparation of a strain with deletions in all of the genes for polyamine biosynthesis
J. Bacteriol.
191
5549-5552
2009
Escherichia coli
Madai, V.I.; Poller, W.C.; Peters, D.; Berger, J.; Paliege, K.; Bernard, R.; Veh, R.W.; Laube, G.
Synaptic localisation of agmatinase in rat cerebral cortex revealed by virtual pre-embedding
Amino Acids
43
1399-1403
2012
Rattus norvegicus
Bernstein, H.G.; Stich, C.; Jaeger, K.; Dobrowolny, H.; Wick, M.; Steiner, J.; Veh, R.; Bogerts, B.; Laube, G.
Agmatinase, an inactivator of the putative endogenous antidepressant agmatine, is strongly upregulated in hippocampal interneurons of subjects with mood disorders
Neuropharmacology
62
237-246
2012
Homo sapiens
Miller, D.; Xu, H.; White, R.H.
A new subfamily of agmatinases present in methanogenic Archaea is Fe(II) dependent
Biochemistry
51
3067-3078
2012
Methanocaldococcus jannaschii (Q57757), Methanocaldococcus jannaschii, Methanocaldococcus jannaschii DSM 2661 (Q57757)
Wang, X.; Ying, W.; Dunlap, K.A.; Lin, G.; Satterfield, M.C.; Burghardt, R.C.; Wu, G.; Bazer, F.W.
Arginine decarboxylase and agmatinase: an alternative pathway for de novo biosynthesis of polyamines for development of mammalian conceptuses
Biol. Reprod.
90
84
2014
Ovis aries (W5PHZ9)
Burnat, M.; Flores, E.
Inactivation of agmatinase expressed in vegetative cells alters arginine catabolism and prevents diazotrophic growth in the heterocyst-forming cyanobacterium Anabaena
MicrobiologyOpen
3
777-792
2014
Anabaena sp. (Q8YUM9), Anabaena sp., Anabaena sp. PCC 7120 (Q8YUM9)
Prunetti, L.; Graf, M.; Blaby, I.K.; Peil, L.; Makkay, A.M.; Starosta, A.L.; Papke, R.T.; Oshima, T., Wilson, D.N.; de Crcy-Lagard, V.
Deciphering the translation initiation factor 5A modification pathway in halophilic Archaea
Archaea
2016
7316725
2016
Haloferax volcanii (D4GWG4), Haloferax volcanii DSM 3757 (D4GWG4)
Lenis, Y.Y.; Elmetwally, M.A.; Tang, W.; Satterfield, C.; Dunlap, K.; Wu, G.; Bazer, F.W.
Functional roles of agmatinase during the peri-implantation period of pregnancy in sheep
Amino Acids
50
293-308
2018
Ovis aries (W5PHZ9), Ovis aries
Shao, Y.; Li, C.; Zhang, W.; Xu, W.; Duan, X.; Li, Y.; Qiu, Q.; Jin, C.
Cloning and comparative analysis the proximal promoter activities of arginase and agmatinase genes in Apostichopus japonicus
Dev. Comp. Immunol.
65
299-308
2016
Apostichopus japonicus (A0A146AXJ2), Apostichopus japonicus
Perez-Mozqueda, L.L.; Vazquez-Duhalt, R.; Castro-Longoria, E.
Role and dynamics of an agmatinase-like protein (AGM-1) in Neurospora crassa
Fungal Genet. Biol.
132
103264
2019
Neurospora crassa (Q1K7T0), Neurospora crassa
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