Reference on EC 3.5.2.6 - beta-lactamase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Dideberg, O.; Charlier, P.; Wery, J.P.; Dehottay, P.; Dusart, J.; Erpicum, T.; Frere, J.M.; Ghuysen, J.M.
The crystal structure of the beta-lactamase of Streptomyces albus G at 0.3 nm resolution
Biochem. J.
245
911-913
1987
Streptomyces albus
Sebo, P.; Stastna, J.
Identification of an inducible penicillinase of the lithoautotrophic hydrogen-oxidizing bacterium Alcaligenes eutrophus
Folia Microbiol. (Praha)
32
376-381
1987
Cupriavidus necator
Sutton, B.J.; Artymiuk, P.J.; Cordero-Barboa, A.E.; Little, C.; Phillips, D.C.; Waley, S.G.
An X-ray-crystallographic study of beta-lactamase II from Bacillus cereus at 0.35 nm resolution
Biochem. J.
248
181-188
1987
Bacillus cereus, Bacillus cereus 569/H/9
Grace, M.E.; Gregory, F.M.; Hung, P.P.; Fu, K.P.
Purification and properties of a beta-lactamase from Proteus penneri
J. Antibiot.
7
938-942
1986
Proteus penneri
-
Conolly, A.K.; Waley, S.G.
Characterization of the membrane beta-lactamase in Bacillus cereus 569/H/9
Biochemistry
22
4647-4651
1983
Bacillus cereus, Bacillus cereus 569/H/9
Erne, A.M.; Zahner, H.; Werner, R.G.
Isolation and characterisation of the potent broad spectrum beta-lactamase AME 1 from Streptomyces antibioticus ssp. antibioticus
FEMS Microbiol. Lett.
16
117-121
1983
Streptomyces antibioticus
-
Magot, M.
Some properties of the Clostridium butyricum group beta-lactamase
J. Gen. Microbiol.
127
113-119
1981
Clostridium butyricum, Clostridium butyricum CB269
Toda, M.; Inoue, M.; Mitsuhashi, S.
Properties of cephalosporinase from Proteus morganii
J. Antibiot.
11
1469-1475
1981
Morganella morganii, Morganella morganii GN5407
Murata, T.; Minami, S.; Yasuda, K.; Iyobe, S.; Inoue, M.; Mitsuhashi, S.
Purification and properties of cephalosporinase from Pseudomonas aeruginosa
J. Antibiot.
9
1164-1170
1981
Pseudomonas aeruginosa, Pseudomonas aeruginosa Dalgleish, Pseudomonas aeruginosa GN10362
Tajima, M.; Takenouchi, Y.; Sugawara, S.; Inoue, M.; Mitsuhashi, S.
Purification and properties of chromosomally mediated beta-lactamase from Citrobacter freundii GN7391
J. Gen. Microbiol.
121
449-456
1980
Citrobacter freundii, Citrobacter freundii GN7391
Ogawara, H.; Mantoku, A.; Shimada, S.
beta-Lactamase from Streptomyces cacaoi. Purification and properties
J. Biol. Chem.
256
2649-2655
1981
Streptomyces cacaoi
Akiba, T.; Horikoshi, K.
A further separation and some properties of beta-lactamase I
Agric. Biol. Chem.
44
2741-2742
1980
Bacillus sp. (in: Bacteria)
-
Philippon, A.; Paul, G.; Barthelemy, M.; Labia, R.; Nevot, P.
Properties of the beta-lactamase (penicillase) produced by Levinea malonatica
FEMS Microbiol. Lett.
8
191-194
1980
Citrobacter koseri, Citrobacter koseri VAN
-
Klemes, Y.; Citri, N.
Preparation and properties of an immobilized derivative of penicillinase
Biotechnol. Bioeng.
21
897-905
1979
Bacillus cereus
Sunaga, T.; Akiba, T.; Horikoshi, K.
Separation and properties of penicillinase of an alkalophilic Bacillus
Agric. Biol. Chem.
43
477-480
1979
Bacillus sp. (in: Bacteria), Bacillus sp. (in: Bacteria) No. 170
-
Matthew, M.
Properies of the beta-lactamase specified by the Pseudomonas plasmid R151
FEMS Microbiol. Lett.
4
241-244
1978
Pseudomonas aeruginosa, Pseudomonas aeruginosa Dalgleish, Pseudomonas aeruginosa PU21 R151
-
Ogawara, H.; Minagawa, T.; Nishizaki, H.
Property of the beta-lactamase from Streptomyces E750-3
J. Antibiot.
9
923-925
1978
Streptomyces sp., Streptomyces sp. E750-3
Ambler, R.P.; Scott, G.K.
Partial amino acid sequence of penicillinase coded by Escherichia coli plasmid R6K
Proc. Natl. Acad. Sci. USA
75
3732-3736
1978
Escherichia coli, Escherichia coli W3310
Matthew, M.; Sykes, R.B.
Properties of the beta-lactamase specified by the Pseudomonas plasmid RPL11
J. Bacteriol.
132
341-345
1977
Pseudomonas aeruginosa, Pseudomonas aeruginosa Dalgleish, Pseudomonas aeruginosa PU21 RPL11
Fujii-Kuriyama, Y.; Yamamoto, M.; Sugawara, S.
Purification and properties of beta-lactamase from Proteus morganii
J. Bacteriol.
131
726-734
1977
Morganella morganii, Morganella morganii 1510
Yamamoto, S.; Lampen, J.O.
Purification of plasma membrane penicillinase from Bacillus licheniformis 749/C and comparison with exoenzyme
J. Biol. Chem.
251
4095-4101
1976
Bacillus licheniformis, Bacillus licheniformis 749/C
Johnson, K.; Duez, C.; Frere, J.M.; Ghuysen, J.M.
beta-Lactamases (Actinomycetes species)
Methods Enzymol.
43
687-698
1975
Streptomyces sp., Streptomyces albus, Streptomyces sp. R39
Ross, G.W.
beta-Lactamase (Enterobacter species)
Methods Enzymol.
43
678-687
1975
Enterobacter cloacae, Enterobacter sp., Enterobacter cloacae P99
Richmond, M.H.
beta-Lactamase (Escherichia coli) R+TEM
Methods Enzymol.
43
672-677
1975
Escherichia coli
Richmond, M.H.
beta-Lactamase (Staphylococcus aureus)
Methods Enzymol.
43
664-672
1975
Staphylococcus aureus
Thatcher, D.R.
beta-Lactamase (Bacillus licheniformis)
Methods Enzymol.
43
652-664
1975
Bacillus licheniformis, Bacillus licheniformis 749/C, Bacillus licheniformis 6346/C
-
Thatcher, D.R.
beta-Lactamase (Bacillus cereus)
Methods Enzymol.
43
640-652
1975
Bacillus cereus, Bacillus cereus 569/H/9, Bacillus cereus 5/B
Richmond, M.H.
Immunological techniques for studying beta-lactamases
Methods Enzymol.
43
86-100
1975
Escherichia coli, Staphylococcus aureus
Ogawara, H.; Umezawa, H.
Bacillus cereus beta-lactamase. Reaction with N-bromosuccinimide and the properties of the product
Biochim. Biophys. Acta
391
435-447
1975
Bacillus cereus, Bacillus subtilis
Furth, A.J.
Purification and properties of a constitutive beta-lactamase from Pseudomonas aeruginosa strain Dalgleish
Biochim. Biophys. Acta
377
431-443
1975
Pseudomonas aeruginosa, Pseudomonas aeruginosa Dalgleish
Davies, R.B.; Abrahym, E.P.
Separation, purification and properties of beta-lactamase I and beta-lactamase II from Bacillus cereus 569/H/9
Biochem. J.
143
115-127
1974
Bacillus cereus, Bacillus cereus 569/H/9
Ross, G.W.; Boulton, M.G.
Purification of beta-lactamases on QAE-sephadex
Biochim. Biophys. Acta
309
430-439
1973
Klebsiella aerogenes, Enterobacter cloacae, Enterobacter cloacae P99, Klebsiella aerogenes 1082E
Ogawara, H.; Maeda, K.; Umezawa, H.
A beta-lactamase of Escherichia coli
Biochim. Biophys. Acta
289
203-211
1972
Escherichia coli
Citri, N.
Penicillinase and other beta-lactamases
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
4
23-46
1971
Enterobacter cloacae, Bacillus cereus, Bacillus licheniformis, Escherichia coli, Staphylococcus aureus
-
Pollock, M.R.
Penicillinase
The Enzymes, 2nd Ed (Boyer, P. D. , Lardy, H. , Myrbck, K. , eds. )
4
269-278
1960
Bacillus cereus, Bacillus subtilis
-
Hammond, G.G.; Huber, J.L.; Greenlee, M.L.; Laub, J.B.; Young, K.; Silver, L.L.; Balkovec, J.M.; Pryor, K.A.D.; Wu, J-K.; Leiting, B.; Pompliano, D.L.; Toney,J.H.
Inhibition of IMP-1 metallo-beta-lactamase and sensitisation of IMP-1-producing bacteria by thioester derivates
FEMS Microbiol. Lett.
179
2193-2199
1999
Bacteroides fragilis, Pseudomonas aeruginosa, Pseudomonas aeruginosa Dalgleish, Pseudomonas aeruginosa Cl5673
-
Ben-Mahrez, K.; Limam, F.; Bellaaj, A.; Rejiba, S.; Ben-Hamouda, T.; Alfeddy, N.; Belhadj, C.; Belhadj, O.
Purification and biochemical properties of beta-lactamase from Escherichia coli
J. Toxicol. Toxin Rev.
18
221-228
1999
Escherichia coli
-
Vakulenko, S.B.; Taibi-Tronche, P.; Toth, M.; Massova, I.; Lerner, S.A.; Mobashery, S.
Effects on substrate profile by mutational substitutions at position 164 and 179 of the class A TEMpUC19beta-lactamase from Escherichia coli
J. Biol. Chem.
274
23052-23060
1999
Escherichia coli, Escherichia coli JM83
Guo, F.; Huynh, J.; Dmitrienko, G.I.; Viswanatha, T.; Clarke, A.J.
The role of the non-conserved residue at position 104 of class A beta-lactamases in susceptibility to mechanism-based inhibitors
Biochim. Biophys. Acta
1431
132-147
1999
Bacillus cereus, Staphylococcus aureus, Bacillus cereus 569/H/9, Staphylococcus aureus PC1
Lin, S.; Thomas, M.; Shlaes, D.M.; Rudin, S.D.; Knox, J.R.; Anderson, V.; Bonomo, R.A.
Kinetic analysis of an inhibitor-resistant variant of the OHIO-1 beta-lactamase, an SHV-family class A enzyme
Biochem. J.
333
395-400
1998
Escherichia coli, Escherichia coli DH5-alpha
Rossolini, G.M.; Franceschini, N.; Riccio, M.L.; Mercuri, P.S.; Perilli, M.; Galleni, M.; Frere, J.M.; Amicosante,G.
Characterisation and sequence of the Chryseobacterium (flavobacterium) meningosepticum carbapenemase: a new molecular class B beta-lactamase showing a broad substrate profile
Biochem. J.
332
145-152
1998
Elizabethkingia meningoseptica
-
Crowder, M.W.; Walsh, T.R.; Banovic, L.; Pettit, M.; Spencer, J.
Overexpression, purification, and characterization of the cloned metallo-beta-lactamase L1 from Stenotrophomonas maltophilia
Antimicrob. Agents Chemother.
42
921-926
1998
Stenotrophomonas maltophilia
Wang, Z.; Benkovic, S.
Purification, characterization, and kinetic studies of a soluble Bacteroides fragilis metallo-beta-lactamase that provides multiple antibiotic resistance
J. Biol. Chem.
273
22402-22408
1998
Bacteroides fragilis
Ledent, P.; Duez, C.; Vanhove, M.; Lejeune, A.; Fonze, E.; Charlier, P.; Rhazi-Filali, F.; Thamm, I.; Guillaume, G.; Samyn, B.; Devreese, B.; Van Beeumen, J.; Lamotte-Brasseur, J.; Frere, J.M.
Unexpected influence of a C-terminal His-tag on the processing of an enzyme and on the kinetic and folding parameters
FEBS Lett.
413
194-196
1997
Bacillus licheniformis, Bacillus licheniformis BS3
Peduzzi, J.; Farzaneh, S.; Reynaud, A.; Barthelemy, M.; Labia, R.
Characterization and amino acid sequence analysis of a new oxyimino cephalosporin-hydrolysing class A beta-lactamase from Serratia fonticolc CUV
Biochim. Biophys. Acta
1341
58-70
1997
Serratia fonticola, Serratia fonticola CUV
Toney, J.H.; Wu, J.K.; Overbye, K.M.; Thompson, C.M.; Pompliano, D.L.
High-yield expression, purification, and characterization of active, soluble Bacteroides fragilis metallo-beta-lactamase, CcrA
Protein Expr. Purif.
9
355-362
1997
Bacteroides fragilis
Feller, G.; Zekhnini, Z.; Lamotte-Brasseur, J.; Gerday, C.
Enzymes from cold-adapted microorganisms: the class C beta-lactamase from antarctic psychrophile Psychrobacter immobilis A5
Eur. J. Biochem.
244
186-191
1997
Psychrobacter immobilis, Psychrobacter immobilis A5
Mariotte-Boyer, S.; Nicolas-Chanoine, M.H.; Labia, R.
A kinetic study of NMC-A beta-lactamase, an Ambler class A carbapenemase also hydrolysing cephamycins
FEMS Microbiol. Lett.
143
29-33
1996
Enterobacter cloacae, Enterobacter cloacae NOR-1
Yang, A.; Bush, K.
Biochemical characterization of the carbapenem-hydrolyzing beta-lactamse AsbM1 from Aeromonas sobria AER 14M; a member of a novel subgroup of metallo-beta-lactamases
FEMS Microbiol. Lett.
137
193-200
1996
Aeromonas sobria, Aeromonas sobria AER14M
Walsh, T.R.; Gamblin, S.; Emery, D.; McGowan, A.P.; Bennett, P.M.
Enzyme kinetics and biochemical analysis of ImiS, the metallo-beta-lactamase from Aeromonas sobria 163a
J. Antimicrob. Chemother.
37
423-431
1996
Aeromonas sobria, Aeromonas sobria 163a
Viadiu, H.; Osuna, J.; Fink, A.L.; Soberon, X.
A new TEM beta-lactamase double mutant with broadened specificity reveals substrate-dependent functional interactions
J. Biol. Chem.
270
781-787
1995
Escherichia coli, Escherichia coli JM101
Brun, T.; Peduzzi, J.; Canica, M.M.; Gerard, P.; Nevot, P.; Barthelemy, M.; Labia, R.
Characterization and amino acid sequence of IRT-4, a novel TEM-type enzyme with a decreased susceptibility to beta-lactamase inhibitors
FEMS Microbiol. Lett.
120
111-118
1994
Escherichia coli, Escherichia coli PEY
Bhopale, G.M.; Naik, S.R.
Penicillinase as a potenitial enzyme marker for enzyme linked immunosorbent assay and its application in immunodiagnostics
Hindustan Antibiot. Bull.
35
157-172
1993
Bacillus cereus
Ledent, P.; Raquet, X.; Joris, B.; Van Beeumen, J.; Frere, J.M.
A comparative study of beta-lactamases
Biochem. J.
292
439-443
1993
Escherichia coli, Escherichia coli JM105
-
Hedberg, M.; Lindqvist, L.; Tuner, K.; Nord, C.E.
Effect of beta-lactamase inhibitors on beta-lactamase from anaerobic bacteria
Eur. J. Clin. Microbiol. Infect. Dis.
11
1100-1104
1992
Bacteroides uniformis, Clostridium butyricum, Fusobacterium nucleatum, Fusobacterium nucleatum F21, Bacteroides uniformis B371, Clostridium butyricum NBL3
Thornewell, J.; Waley, G.
Site-directed mutagenesis and substrate-induced inactivation of beta-lactamase I
Biochem. J.
288
1045-1051
1992
Bacillus cereus, Bacillus subtilis, Bacillus cereus 569/H/9
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Hedberg, M.; Lindqvist, L.; Tuner, K.; Nord, C.E.
Effect of clavulanic acid, sulbactam and tazobactam on three different beta-lactamases from Bacteroides uniformes, Clostridium butyricum and Fusobacterium nucleatum
J. Antimicrob. Chemother.
30
17-25
1992
Bacteroides uniformis, Clostridium butyricum, Fusobacterium nucleatum
Eliasson, I.; Kamme, C.; Vang, M.; Waley, S.G.
Characterization of cell-bound papain-soluble beta-lactamases in BRO-1 and BRO-2 producing strains of Moraxella (Branhamella) catarrhalis and Moraxella nonliquefaciens
Eur. J. Clin. Microbiol. Infect. Dis.
11
313-321
1992
Moraxella catarrhalis, Moraxella nonliquefaciens
Zygmunt, D.J.; Stratton, C.W.; Kernodle, D.S.
Characterization of four beta-lactamases produced by Straphylococcus aureus
Antimicrob. Agents Chemother.
36
440-445
1992
Staphylococcus aureus, Staphylococcus aureus PC1
Wang, H.Y.; Zhang, M.; Imanaka, T.
Screening and separation of beta-lactam antibiotics using protein-engineered enzymes
Ann. N. Y. Acad. Sci.
613
376-384
1990
Bacillus licheniformis, Streptomyces sp.
Ellerby, L.M.; Escobar, W.A.; Fink, A.L.; Mitchinson, C.; Wells, J.A.
The role of lysine-234 in beta-lactamase catalysis probed by site directed mutagenesis
Biochemistry
29
5797-5806
1990
Bacillus licheniformis
Kuzin, A.P.; Nukaga, M.; Nukaga, Y.; Hujer, A.; Bonomo, R.A.; Knox, J.R.
Inhibition of the SHV-1 beta-lactamase by sulfones: crystallographic observation of two reaction intermediates with tazobactam
Biochemistry
40
1861-1866
2001
Klebsiella pneumoniae (P0AD64), Klebsiella pneumoniae 15571 (P0AD64)
Lim, D.; Sanschagrin, F.; Passmore, L.; De Castro, L.; Levesque, R.C.; Strynadka, N.C.
Insights into the molecular basis for the carbenicillinase activity of PSE-4 beta-lactamase from crystallographic and kinetic studies
Biochemistry
40
395-402
2001
Pseudomonas aeruginosa (P16897), Pseudomonas aeruginosa
Trehan, I.; Beadle, B.M.; Shoichet, B.K.
Inhibition of AmpC beta-lactamase through a destabilizing interaction in the active site
Biochemistry
40
7992-7999
2001
Escherichia coli (P00811), Escherichia coli, Escherichia coli JM109 (P00811)
Fonze, E.; Vanhove, M.; Dive, G.; Sauvage, E.; Frere, J.M.; Charlier, P.
Crystal structures of the Bacillus licheniformis BS3 class A beta-lactamase and of the acyl-enzyme adduct formed with cefoxitin
Biochemistry
41
1877-1885
2002
Bacillus licheniformis (P00808)
Bell, J.H.; Pratt, R.F.
Mechanism of inhibition of the beta-lactamase of Enterobacter cloacae P99 by 1:1 complexes of vanadate with hydroxamic acids
Biochemistry
41
4329-4338
2002
Enterobacter cloacae (P05364), Enterobacter cloacae P99 (P05364), Enterobacter cloacae P99
Kumar, S.; Adediran, S.A.; Nukaga, M.; Pratt, R.F.
Kinetics of turnover of cefotaxime by the Enterobacter cloacae P99 and GCl beta-lactamases: two free enzyme forms of the P99 beta-lactamase detected by a combination of pre- and post-steady state kinetics
Biochemistry
43
2664-2672
2004
Enterobacter cloacae, Enterobacter cloacae P99, Enterobacter cloacae GC1
Curley, K.; Pratt, R.F.
The oxyanion hole in serine beta-lactamase catalysis: interactions of thiono substrates with the active site
Bioorg. Chem.
28
338-356
2000
Enterobacter cloacae, Enterobacter cloacae P99
Bounaga, S.; Galleni, M.; Laws, A.P.; Page, M.I.
Cysteinyl peptide inhibitors of Bacillus cereus zinc beta-lactamase
Bioorg. Med. Chem.
9
503-510
2001
Bacillus cereus
Denny, B.J.; Lambert, P.A.; West, P.W.J.
The flavonoid galangin inhibits the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia
FEMS Microbiol. Lett.
208
21-24
2002
Stenotrophomonas maltophilia
Garcia-Saez, I.; Hopkins, J.; Papamicael, C.; Franceschini, N.; Amicosante, G.; Rossolini, G.M.; Galleni, M.; Frere, J.M.; Dideberg, O.
The 1.5-A structure of Chryseobacterium meningosepticum zinc beta-lactamase in complex with the inhibitor, D-captopril
J. Biol. Chem.
278
23868-23873
2003
Elizabethkingia meningoseptica
Pagan-Rodriguez, D.; Zhou, X.; Simmons, R.; Bethel, C.R.; Hujer, A.M.; Helfand, M.S.; Jin, Z.; Guo, B.; Anderson, V.E.; Ng, L.M.; Bonomo, R.A.
Tazobactam inactivation of SHV-1 and the inhibitor-resistant Ser130 -->Gly SHV-1 beta-lactamase: insights into the mechanism of inhibition
J. Biol. Chem.
279
19494-19501
2004
Klebsiella pneumoniae
Zhang, Z.; Palzkill, T.
Dissecting the protein-protein interface between beta-lactamase inhibitory protein and class A beta-lactamases
J. Biol. Chem.
279
42860-42866
2004
Bacillus anthracis, Escherichia coli (P62593), Klebsiella pneumoniae (P0AD64), Serratia marcescens
Garrity, J.D.; Carenbauer, A.L.; Herron, L.R.; Crowder, M.W.
Metal binding Asp-120 in metallo-beta-lactamase L1 from Stenotrophomonas maltophilia plays a crucial role in catalysis
J. Biol. Chem.
279
920-927
2004
Stenotrophomonas maltophilia (P52700), Stenotrophomonas maltophilia
Paetzel, M.; Danel, F.; de Castro, L.; Mosimann, S.C.; Page, M.G.; Strynadka, N.C.
Crystal structure of the class D beta-lactamase OXA-10
Nat. Struct. Biol.
7
918-925
2000
Pseudomonas aeruginosa (P14489), Pseudomonas aeruginosa
Huang, W.; Beharry, Z.; Zhang, Z.; Palzkill, T.
A broad-spectrum peptide inhibitor of beta-lactamase identified using phage display and peptide arrays
Protein Eng.
16
853-860
2003
Enterobacter cloacae, Bacillus anthracis, Escherichia coli
Lawung, R.; Prachayasittikul, V.; Bulow, L.
Purification and characterization of a beta-lactamase from Haemophilus ducreyi in Escherichia coli
Protein Expr. Purif.
23
151-158
2001
[Haemophilus] ducreyi
Sun, T.; Nukaga, M.; Mayama, K.; Braswell, E.H.; Knox, J.R.
Comparison of beta-lactamases of classes A and D: 1.5-A crystallographic structure of the class D OXA-1 oxacillinase
Protein Sci.
12
82-91
2003
Escherichia coli
Taylor, S.C.
Development of an immobilised lactamase resolution process for the (+)-gamma-lactam and the ring-opened (-)-amino acid
Chirality Ind.
2
187-188
1997
Microbacterium sp.
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Taylor, S.J.C.; Sutherland, A.G.; Lee, C.; Wisdom, R.; Thomas, S.; Roberts, S.M.; Evans, C.
Chemoenzymatic synthesis of (-)carbovir utilizing a whole cell catalyzed resolution of a 2-azabicyclo[2.2.1]hept-5-en-3-one
J. Chem. Soc. Chem. Commun.
1990
1120-1121
1990
Ralstonia solanacearum
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Wu, S.W.; Liang, Y.H.; Su, X.D.
Expression, purification and crystallization of an extended-spectrum beta-lactamase from Klebsiella oxytoca
Acta Crystallogr. Sect. D
60
326-328
2004
Klebsiella oxytoca
Lee, S.J.; Kim, J.Y.; Jung, H.I.; Suh, P.G.; Lee, H.S.; Lee, S.H.; Cha, S.S.
Crystallization and preliminary X-ray crystallographic analyses of CMY-1 and CMY-10, plasmidic class C beta-lactamases with extended substrate spectrum
Acta Crystallogr. Sect. D
60
382-384
2004
Klebsiella pneumoniae
Sharma, N.; Toney, J.H.; Fitzgerald, P.M.
Expression, purification, crystallization and preliminary X-ray analysis of Aeromonas hydrophilia metallo-beta-lactamase
Acta Crystallogr. Sect. F
61
180-182
2005
Aeromonas hydrophila
Beceiro, A.; Dominguez, L.; Ribera, A.; Vila, J.; Molina, F.; Villanueva, R.; Eiros, J.M.; Bou, G.
Molecular characterization of the gene encoding a new AmpC beta-lactamase in a clinical strain of acinetobacter genomic species 3
Antimicrob. Agents Chemother.
48
1374-1378
2004
Acinetobacter pittii (Q7WZ37)
Higgins, P.G.; Wisplinghoff, H.; Stefanik, D.; Seifert, H.
In vitro activities of the beta-lactamase inhibitors clavulanic acid, sulbactam, and tazobactam alone or in combination with beta-lactams against epidemiologically characterized multidrug-resistant Acinetobacter baumannii strains
Antimicrob. Agents Chemother.
48
1586-1592
2004
Acinetobacter baumannii
Heritier, C.; Poirel, L.; Nordmann, P.
Genetic and biochemical characterization of a chromosome-encoded carbapenem-hydrolyzing ambler class D beta-lactamase from Shewanella algae
Antimicrob. Agents Chemother.
48
1670-1675
2004
Shewanella algae (Q6VCW0), Shewanella algae
Girlich, D.; Naas, T.; Nordmann, P.
Biochemical characterization of the naturally occurring oxacillinase OXA-50 of Pseudomonas aeruginosa
Antimicrob. Agents Chemother.
48
2043-2048
2004
Pseudomonas aeruginosa (Q6PL88), Pseudomonas aeruginosa
Henriques, I.; Moura, A.; Alves, A.; Saavedra, M.J.; Correia, A.
Molecular characterization of a carbapenem-hydrolyzing class A beta-lactamase, SFC-1, from Serratia fonticola UTAD54
Antimicrob. Agents Chemother.
48
2321-2324
2004
Serratia fonticola (Q6JP75), Serratia fonticola, Serratia fonticola UTAD54 (Q6JP75), Serratia fonticola UTAD54
Doi, Y.; Wachino, J.; Ishiguro, M.; Kurokawa, H.; Yamane, K.; Shibata, N.; Shibayama, K.; Yokoyama, K.; Kato, H.; Yagi, T.; Arakawa, Y.
Inhibitor-sensitive AmpC beta-lactamase variant produced by an Escherichia coli clinical isolate resistant to oxyiminocephalosporins and cephamycins
Antimicrob. Agents Chemother.
48
2652-2658
2004
Escherichia coli (Q76DI4), Escherichia coli, Escherichia coli HKY28 (Q76DI4), Escherichia coli HKY28
Caporale, B.; Franceschini, N.; Perilli, M.; Segatore, B.; Rossolini, G.M.; Amicosante, G.
Biochemical characterization of laboratory mutants of extended-spectrum beta-lactamase TEM-60
Antimicrob. Agents Chemother.
48
3579-3582
2004
Providencia stuartii
Castanheira, M.; Toleman, M.A.; Jones, R.N.; Schmidt, F.J.; Walsh, T.R.
Molecular characterization of a beta-lactamase gene, blaGIM-1, encoding a new subclass of metallo-beta-lactamase
Antimicrob. Agents Chemother.
48
4654-4661
2004
Pseudomonas aeruginosa (Q704U4), Pseudomonas aeruginosa
Docquier, J.D.; Lopizzo, T.; Liberatori, S.; Prenna, M.; Thaller, M.C.; Frere, J.M.; Rossolini, G.M.
Biochemical characterization of the THIN-B metallo-beta-lactamase of Janthinobacterium lividum
Antimicrob. Agents Chemother.
48
4778-4783
2004
Janthinobacterium lividum
Munday, C.J.; Boyd, D.A.; Brenwald, N.; Miller, M.; Andrews, J.M.; Wise, R.; Mulvey, M.R.; Hawkey, P.M.
Molecular and kinetic comparison of the novel extended-spectrum beta-lactamases CTX-M-25 and CTX-M-26
Antimicrob. Agents Chemother.
48
4829-4834
2004
Klebsiella pneumoniae (Q8GD10), Klebsiella pneumoniae, Escherichia coli (Q8KSA6), Escherichia coli
Brinas, L.; Moreno, M.A.; Teshager, T.; Saenz, Y.; Porrero, M.C.; Dominguez, L.; Torres, C.
Monitoring and characterization of extended-spectrum beta-lactamases in Escherichia coli strains from healthy and sick animals in Spain in 2003
Antimicrob. Agents Chemother.
49
1262-1264
2005
Escherichia coli
Keith, K.E.; Oyston, P.C.; Crossett, B.; Fairweather, N.F.; Titball, R.W.; Walsh, T.R.; Brown, K.A.
Functional characterization of OXA-57, a class D beta-lactamase from Burkholderia pseudomallei
Antimicrob. Agents Chemother.
49
1639-1641
2005
Burkholderia pseudomallei
Lau, S.K.; Ho, P.L.; Li, M.W.; Tsoi, H.W.; Yung, R.W.; Woo, P.C.; Yuen, K.Y.
Cloning and characterization of a chromosomal class C beta-lactamase and its regulatory gene in Laribacter hongkongensis
Antimicrob. Agents Chemother.
49
1957-1964
2005
Laribacter hongkongensis (Q6GVZ4), Laribacter hongkongensis
Poirel, L.; Brinas, L.; Verlinde, A.; Ide, L.; Nordmann, P.
BEL-1, a novel clavulanic acid-inhibited extended-spectrum beta-lactamase, and the class 1 integron In120 in Pseudomonas aeruginosa
Antimicrob. Agents Chemother.
49
3743-3748
2005
Pseudomonas aeruginosa (Q3SAW3), Pseudomonas aeruginosa
Heritier, C.; Poirel, L.; Fournier, P.E.; Claverie, J.M.; Raoult, D.; Nordmann, P.
Characterization of the naturally occurring oxacillinase of Acinetobacter baumannii
Antimicrob. Agents Chemother.
49
4174-4179
2005
Acinetobacter baumannii (Q5I2N2), Acinetobacter baumannii
Bauvois, C.; Ibuka, A.S.; Celso, A.; Alba, J.; Ishii, Y.; Frere, J.M.; Galleni, M.
Kinetic properties of four plasmid-mediated AmpC beta-lactamases
Antimicrob. Agents Chemother.
49
4240-4246
2005
Escherichia coli
Gacar, G.G.; Midilli, K.; Kolayli, F.; Ergen, K.; Gundes, S.; Hosoglu, S.; Karadenizli, A.; Vahaboglu, H.
Genetic and enzymatic properties of metallo-beta-lactamase VIM-5 from a clinical isolate of Enterobacter cloacae
Antimicrob. Agents Chemother.
49
4400-4403
2005
Enterobacter cloacae (Q4ZE97), Enterobacter cloacae
Quinteira, S.; Sousa, J.C.; Peixe, L.
Characterization of In100, a new integron carrying a metallo-{beta}-lactamase and a carbenicillinase, from Pseudomonas aeruginosa
Antimicrob. Agents Chemother.
49
451-453
2005
Pseudomonas aeruginosa (Q9K2N0), Pseudomonas aeruginosa
Alba, J.; Ishii, Y.; Thomson, K.; Moland, E.S.; Yamaguchi, K.
Kinetics study of KPC-3, a plasmid-encoded class A carbapenem-hydrolyzing beta-lactamase
Antimicrob. Agents Chemother.
49
4760-4762
2005
Escherichia coli
Sauvage, E.; Fonze, E.; Quinting, B.; Galleni, M.; Frere, J.M.; Charlier, P.
Crystal structure of the Mycobacterium fortuitum class A beta-lactamase: structural basis for broad substrate specificity
Antimicrob. Agents Chemother.
50
2516-2521
2006
Mycolicibacterium fortuitum (Q59517), Mycolicibacterium fortuitum
Voha, C.; Docquier, J.D.; Rossolini, G.M.; Fosse, T.
Genetic and biochemical characterization of FUS-1 (OXA-85), a narrow-spectrum class D beta-lactamase from Fusobacterium nucleatum subsp. polymorphum
Antimicrob. Agents Chemother.
50
2673-2679
2006
Fusobacterium nucleatum (Q6XL56), Fusobacterium nucleatum
Wang, F.; Cassidy, C.; Sacchettini, J.C.
Crystal structure and activity studies of the Mycobacterium tuberculosis beta-lactamase reveal its critical role in resistance to beta-lactam antibiotics
Antimicrob. Agents Chemother.
50
2762-2771
2006
Mycobacterium tuberculosis
Power, P.; Galleni, M.; Ayala, J.A.; Gutkind, G.
Biochemical and molecular characterization of three new variants of AmpC beta-lactamases from Morganella morganii
Antimicrob. Agents Chemother.
50
962-967
2006
Morganella morganii subsp. morganii (Q704Y9), Morganella morganii subsp. morganii (Q704Z0), Morganella morganii subsp. morganii (Q705J0), Morganella morganii subsp. morganii PP37 (Q704Y9), Morganella morganii subsp. morganii PP19 (Q705J0), Morganella morganii subsp. morganii PP29 (Q704Z0)
Weng, S.F.; Chao, Y.F.; Lin, J.W.
Identification and characteristic analysis of the ampC gene encoding beta-lactamase from Vibrio fischeri
Biochem. Biophys. Res. Commun.
314
838-843
2004
Aliivibrio fischeri (Q6T3Q5), Aliivibrio fischeri
Lin, J.W.; Weng, S.F.; Chao, Y.F.; Chung, Y.T.
Characteristic analysis of the ampC gene encoding beta-lactamase from Photobacterium phosphoreum
Biochem. Biophys. Res. Commun.
326
539-547
2005
Photobacterium phosphoreum (Q5MJG5), Photobacterium phosphoreum
Simm, A.M.; Loveridge, E.J.; Crosby, J.; Avison, M.B.; Walsh, T.R.; Bennett, P.M.
Bulgecin A: a novel inhibitor of binuclear metallo-beta-lactamases
Biochem. J.
387
585-590
2005
Bacillus cereus, Aeromonas veronii, Stenotrophomonas maltophilia (P52700), Stenotrophomonas maltophilia
Badarau, A.; Llinas, A.; Laws, A.P.; Damblon, C.; Page, M.I.
Inhibitors of metallo-beta-lactamase generated from beta-lactam antibiotics
Biochemistry
44
8578-8589
2005
Bacillus cereus
Jin, W.; Arakawa, Y.; Yasuzawa, H.; Taki, T.; Hashiguchi, R.; Mitsutani, K.; Shoga, A.; Yamaguchi, Y.; Kurosaki, H.; Shibata, N.; Ohta, M.; Goto, M.
Comparative study of the inhibition of metallo-beta-lactamases (IMP-1 and VIM-2) by thiol compounds that contain a hydrophobic group
Biol. Pharm. Bull.
27
851-856
2004
Pseudomonas aeruginosa, Serratia marcescens
Brown, S.; Young, H.K.; Amyes, S.G.
Characterisation of OXA-51, a novel class D carbapenemase found in genetically unrelated clinical strains of Acinetobacter baumannii from Argentina
Clin. Microbiol. Infect.
11
15-23
2005
Acinetobacter baumannii (Q5QT35), Acinetobacter baumannii
Luzzaro, F.; Endimiani, A.; Docquier, J.D.; Mugnaioli, C.; Bonsignori, M.; Amicosante, G.; Rossolini, G.M.; Toniolo, A.
Prevalence and characterization of metallo-beta-lactamases in clinical isolates of Pseudomonas aeruginosa
Diagn. Microbiol. Infect. Dis.
48
131-135
2004
Pseudomonas aeruginosa
Villegas, M.V.; Correa, A.; Perez, F.; Miranda, M.C.; Zuluaga, T.; Quinn, J.P.; Quinn, J.P.
Prevalence and characterization of extended-spectrum beta-lactamases in Klebsiella pneumoniae and Escherichia coli isolates from Colombian hospitals
Diagn. Microbiol. Infect. Dis.
49
217-222
2004
Escherichia coli, Klebsiella pneumoniae
Petrella, S.; Renard, M.; Ziental-Gelus, N.; Clermont, D.; Jarlier, V.; Sougakoff, W.
Characterization of the chromosomal class A beta-lactamase CKO from Citrobacter koseri
FEMS Microbiol. Lett.
254
285-292
2006
Citrobacter koseri, Citrobacter koseri (Q708V3), Citrobacter koseri (Q708V4), Citrobacter koseri (Q8RNV0), Citrobacter koseri (Q9AL74), Citrobacter koseri CK4
Sharma, S.; Mittal, S.; Mallik, S.; Virdi, J.S.
Molecular characterization of beta-lactamase genes blaA and blaB of Yersinia enterocolitica biovar 1A
FEMS Microbiol. Lett.
257
319-327
2006
Yersinia enterocolitica (Q45EY0), Yersinia enterocolitica (Q58G58), Yersinia enterocolitica
Mammeri, H.; Poirel, L.; Nazik, H.; Nordmann, P.
Cloning and functional characterization of the ambler class C beta-lactamase of Yersinia ruckeri
FEMS Microbiol. Lett.
257
57-62
2006
Yersinia ruckeri (Q20I87), Yersinia ruckeri
Kong, K.F.; Jayawardena, S.R.; Del Puerto, A.; Wiehlmann, L.; Laabs, U.; Tuemmler, B.; Mathee, K.
Characterization of poxB, a chromosomal-encoded Pseudomonas aeruginosa oxacillinase
Gene
358
82-92
2005
Pseudomonas aeruginosa
Schiefer, A.M.; Wiegand, I.; Sherwood, K.J.; Wiedemann, B.; Stock, I.
Biochemical and genetic characterization of the beta-lactamases of Y. aldovae, Y. bercovieri, Y. frederiksenii and "Y. ruckeri" strains
Int. J. Antimicrob. Agents
25
496-500
2005
Yersinia aldovae, Yersinia bercovieri, Yersinia frederiksenii, Yersinia ruckeri
Bonnefoy, A.; Dupuis-Hamelin, C.; Steier, V.; Delachaume, C.; Seys, C.; Stachyra, T.; Fairley, M.; Guitton, M.; Lampilas, M.
In vitro activity of AVE1330A, an innovative broad-spectrum non-beta-lactam beta-lactamase inhibitor
J. Antimicrob. Chemother.
54
410-417
2004
Enterobacter cloacae, Escherichia coli, Enterobacter cloacae 293HT6
Sanschagrin, F.; Levesque, R.C.
A specific peptide inhibitor of the class B metallo-beta-lactamase L-1 from Stenotrophomonas maltophilia identified using phage display
J. Antimicrob. Chemother.
55
252-255
2005
Stenotrophomonas maltophilia
Ho, P.L.; Shek, R.H.; Chow, K.H.; Duan, R.S.; Mak, G.C.; Lai, E.L.; Yam, W.C.; Tsang, K.W.; Lai, W.M.
Detection and characterization of extended-spectrum beta-lactamases among bloodstream isolates of Enterobacter spp. in Hong Kong, 2000-2002
J. Antimicrob. Chemother.
55
326-332
2005
Enterobacter hormaechei, Klebsiella aerogenes, Klebsiella aerogenes 255B4, no activity in Enterobacter agglomerans, no activity in Enterobacter asburiae, no activity in Enterobacter cloacae, no activity in Enterobacter gergoviae, no activity in Enterobacter sakazakii
Poirel, L.; Heritier, C.; Nordmann, P.
Genetic and biochemical characterization of the chromosome-encoded class B beta-lactamases from Shewanella livingstonensis (SLB-1) and Shewanella frigidimarina (SFB-1)
J. Antimicrob. Chemother.
55
680-685
2005
Shewanella frigidimarina (Q53BU0), Shewanella frigidimarina, Shewanella livingstonensis (Q53BU1), Shewanella livingstonensis
de la Prieta, M.C.; Francia, M.V.; Seoane, A.; Lobo, J.M.
Characterization of defective beta-lactamase genes in Yersinia enterocolitica
J. Antimicrob. Chemother.
58
661-664
2006
Yersinia enterocolitica, Yersinia enterocolitica (Q01166), Yersinia enterocolitica Y56 (Q01166), Yersinia enterocolitica IP97
Yamaguchi, Y.; Kuroki, T.; Yasuzawa, H.; Higashi, T.; Jin, W.; Kawanami, A.; Yamagata, Y.; Arakawa, Y.; Goto, M.; Kurosaki, H.
Probing the role of Asp-120(81) of metallo-beta-lactamase (IMP-1) by site-directed mutagenesis, kinetic studies, and X-ray crystallography
J. Biol. Chem.
280
20824-20832
2005
Serratia marcescens (P52699)
Black, J.A.; Thomson, K.S.; Buynak, J.D.; Pitout, J.D.
Evaluation of beta-lactamase inhibitors in disk tests for detection of plasmid-mediated AmpC beta-lactamases in well-characterized clinical strains of Klebsiella spp
J. Clin. Microbiol.
43
4168-4171
2005
Klebsiella sp.
Garau, G.; Bebrone, C.; Anne, C.; Galleni, M.; Frere, J.M.; Dideberg, O.
A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem
J. Mol. Biol.
345
785-795
2005
Aeromonas hydrophila (P26918), Aeromonas hydrophila
Perumal, S.K.; Pratt, R.F.
Synthesis and evaluation of ketophosph(on)ates as beta-lactamase inhibitors
J. Org. Chem.
71
4778-4785
2006
Enterobacter cloacae, Escherichia coli, Enterobacter cloacae P99
Liebana, E.; Gibbs, M.; Clouting, C.; Barker, L.; Clifton-Hadley, F.A.; Pleydell, E.; Abdalhamid, B.; Hanson, N.D.; Martin, L.; Poppe, C.; Davies, R.H.
Characterization of beta-lactamases responsible for resistance to extended-spectrum cephalosporins in Escherichia coli and Salmonella enterica strains from food-producing animals in the United Kingdom
Microb. Drug Resist.
10
1-9
2004
Escherichia coli, Salmonella enterica
Docquier, J.D.; Riccio, M.L.; Mugnaioli, C.; Luzzaro, F.; Endimiani, A.; Toniolo, A.; Amicosante, G.; Rossolini, G.M.
IMP-12, a new plasmid-encoded metallo-beta-lactamase from a Pseudomonas putida clinical isolate.
Antimicrob. Agents Chemother.
47
1522-1528
2003
Pseudomonas putida (Q8GIW8), Pseudomonas putida
Poirel, L.; Cabanne, L.; Collet, L.; Nordmann, P.
Class II transposon-borne structure harboring metallo-beta-lactamase gene blaVIM-2 in Pseudomonas putida.
Antimicrob. Agents Chemother.
50
2889-2891
2006
Pseudomonas putida (Q7BJM5), Pseudomonas putida
Lombardi, G.; Luzzaro, F.; Docquier, J.D.; Riccio, M.L.; Perilli, M.; Coli, A.; Amicosante, G.; Rossolini, G.M.; Toniolo, A.
Nosocomial infections caused by multidrug-resistant isolates of Pseudomonas putida producing VIM-1 metallo-beta-lactamase.
J. Clin. Microbiol.
40
4051-4055
2002
Pseudomonas putida (Q8G979), Pseudomonas putida
Horsfall, L.E.; Garau, G.; Lienard, B.M.; Dideberg, O.; Schofield, C.J.; Frere, J.M.; Galleni, M.
Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila
Antimicrob. Agents Chemother.
51
2136-2142
2007
Aeromonas hydrophila (P26918), Aeromonas hydrophila
Perilli, M.; Caporale, B.; Celenza, G.; Pellegrini, C.; Docquier, J.D.; Mezzatesta, M.; Rossolini, G.M.; Stefani, S.; Amicosante, G.
Identification and characterization of a new metallo-beta-lactamase, IND-5, from a clinical isolate of Chryseobacterium indologenes
Antimicrob. Agents Chemother.
51
2988-2990
2006
Chryseobacterium indologenes (Q6JE29), Chryseobacterium indologenes
Girlich, D. ; Leclercq, R. ; Naas, T.; Nordmanni, P.
Molecular and biochemical characterization of the chromosome-encoded class A beta-lactamase BCL-1 from Bacillus clausii
Antimicrob. Agents Chemother.
51
4009-4014
2007
Alkalihalobacillus clausii (A8RR46), Alkalihalobacillus clausii, Alkalihalobacillus clausii NR (A8RR46)
Fonseca, F.; Sarmento, A.C.; Henriques, I.; Samyn, B.; van Beeumen, J.; Domingues,P.; Domingues, M.R.; Saavedra, M.J.; and Correia, A.
Biochemical characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase
Antimicrob. Agents Chemother.
51
4512-4514
2007
Serratia fonticola, Serratia fonticola UTAD54
Meziane-Cherif, D.; Lambert, T.; Dupechez, M.; Courvalin, P.; Galimand, M.
Genetic and biochemical characterization of OXA-63, a new class D beta lactamase from Brachyspira pilosicoli BM4442
Antimicrob. Agents Chemother.
52
1264-1268
2008
Brachyspira pilosicoli (Q50H31), Brachyspira pilosicoli BM4442 (Q50H31), Brachyspira pilosicoli BM4442
Doi, Y.; Poirel, L.; Paterson, D.L.; Nordmann, P.
Characterization of a naturally occurring class D beta-lactamase from Achromobacter xylosoxidans
Antimicrob. Agents Chemother.
52
1952-1956
2008
Achromobacter xylosoxidans (B3FIE3), Achromobacter xylosoxidans
Marchiaro, P.; Tomatis, P.E.; Mussi, M.A.; Pasteran, F.; Viale, A.M; Limansky, A.S.; Vila, A.J.
Biochemical characterization of metallo-beta-lactamase VIM-11 from a Pseudomonas aeruginosa clinical strain
Antimicrob. Agents Chemother.
52
2250-2252
2007
Pseudomonas aeruginosa, Pseudomonas aeruginosa M5109
Banic, S.
Detection of bacterial strains producing sulbactam- or tazobactam-sensitive beta-lactamases by the use of disks containing the inhibitors alone instead of combining them with antibiotics
APMIS
114
3-9
2006
Morganella morganii, Morganella morganii No. 14337
Hugonnet, J.E.; Blanchard, J.S.
Irreversible inhibition of the Mycobacterium tuberculosis beta-lactamase by clavulanate
Biochemistry
46
11998-12004
2007
Mycobacterium tuberculosis
Kontou, M.; Pournaras, S.; Kristo, I.; Ikonomidis, A.; Maniatis, A.N.; Stathopoulos, C.
Molecular cloning and biochemical characterization of VIM-12, a novel hybrid VIM-1/VIM-2 metallo-beta-lactamase from a Klebsiella pneumoniae clinical isolate, reveal atypical substrate specificity
Biochemistry
46
13170-13178
2007
Klebsiella pneumoniae, Klebsiella pneumoniae 2873
Helfand, M.S.; Taracila, M.A.; Totir, M.A.; Bonomo, R.A.; Buynak, J.D.; van den Akker, F.; Carey, P.R.
Raman crystallographic studies of the intermediates formed by Ser130Gly SHV, a beta-lactamase that confers resistance to clinical inhibitors
Biochemistry
46
8689-8699
2007
Klebsiella pneumoniae
Lienard, B.M.; Horsfall, L.E.; Galleni, M.; Frere, J.M.; Schofield, C.J.
Inhibitors of the FEZ-1 metallo-beta-lactamase
Bioorg. Med. Chem. Lett.
17
964-968
2007
Fluoribacter gormanii
Mittal, S.; Mallik, S.; Sharma, S.;Virdi, J.S.
Characteristics of beta-lactamases and their genes (blaA and blaB) in Yersinia intermedia and Y. frederiksenii
BMC Microbiol.
7
25
2007
Yersinia frederiksenii (Q0ZA00), Yersinia frederiksenii (Q1W755), Yersinia frederiksenii, Yersinia intermedia (Q1W756), Yersinia intermedia (Q1W758), Yersinia intermedia, Yersinia frederiksenii C-115 (Q0ZA00), Yersinia frederiksenii C-115 (Q1W755), Yersinia intermedia C-702 (Q1W756), Yersinia intermedia C-702 (Q1W758)
Kurosaki, H.; Yamaquchi, Y.; Yasuzawa, H.; Jin, W.; Yamagata, Y.; Arakawa, Y.
Probing, inhibition, and crystallographic characterization of metallo-beta -lactamase (IMP-1) with fluorescent agents containing dansyl and thiol groups
ChemMedChem
1
969-972
2006
Serratia marcescens (P52699)
Zhao, W.H.; Hu, Z.Q.; Chen, G.; Ito, R.; Shimamura, T.
Hyperproduction of inhibitor-susceptible TEM beta-lactamase is responsible for resistance of Serratia marcescens to beta-lactam-beta-lactamase inhibitor combinations
Chemotherapy
54
31-37
2008
Serratia marcescens
Kanj, S.S.; Corkill, J.E.; Kanafani, Z.A.; Araj, G.F.; Hart, C.A.; Jaafar, R.; Matar, G.M.
Molecular characterisation of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella spp. isolates at a tertiary-care centre in Lebanon
Clin. Microbiol. Infect.
14
501-504
2008
Escherichia coli, Klebsiella sp.
Bae, I.K.; Lee, Y-N.; Jeong, S.H.; Hong, S.G.; Lee, J.H.; Lee, S.H.; Kim, H.J.; Youn, H.
Genetic and biochemical characterization of GES-5, an extended-spectrum class A beta-lactamase from Klebsiella pneumoniae
Diagn. Microbiol. Infect. Dis.
58
465-468
2007
Klebsiella pneumoniae (Q09HD0), Klebsiella pneumoniae, Klebsiella pneumoniae CHAK36 (Q09HD0)
Michaux, C.; Massant, J.; Kerff, F.; Frere, J.M.; Docquier, J.D.; Vandenberghe, I.; Samyn, B.; Pierrard, A.; Feller, G.; Charlier, P.; Van Beeumen, J.; Wouters, J.
Crystal structure of a cold-adapted class C beta-lactamase
FEBS J.
275
1687-1697
2008
Psychrobacter immobilis, Serratia marcescens, Enterobacter cloacae (P05364), Pseudomonas fluorescens (P85302), Pseudomonas fluorescens, Pseudomonas fluorescens TAE4 (P85302), Enterobacter cloacae 908R (P05364)
Hu, G.-Z.; Chen, H.-Y.; Si, H.-B.; Deng, L.-X.; Wei, Z.-Y.; Yuan, L.; Kuang, X.-H.
Phenotypic and molecular characterization of TEM-116 extended-spectrum beta-lactamase produced by a Shigella flexneri clinical isolate from chickens
FEMS Microbiol. Lett.
279
162-166
2008
Shigella flexneri (Q3HLW6), Shigella flexneri
Ishii, Y.; Galleni, M.; Ma, L.; Frere, J.-M.; Yamaguchi, K.
Biochemical characterisation of the CTX-M-14 beta-lactamase
Int. J. Antimicrob. Agents
29
159-164
2007
Escherichia coli, Escherichia coli TUM1121
Rodriguez, M.M.; Power, P.; Bauvois, C.; Di Conza, J.; Ayala, J.A.; Galleni, M.; Gutkind, G.
Characterisation of KLUA-9, a beta-lactamase from extended-spectrum cephalosporin-susceptible Kluyvera ascorbata, and genetic organisation of blaKLUA-9
Int. J. Antimicrob. Agents
29
332-337
2007
Kluyvera ascorbata, Kluyvera ascorbata 68
Wyrembak, P.N.; Babaoglu, K.; Pelto, R.B.; Shoichet, B.K.; Pratt, R.F.
O-aryloxycarbonyl hydroxamates: New beta-lactamase inhibitors that cross-link the active Site
J. Am. Chem. Soc.
129
9548-9549
2007
Enterobacter cloacae, Enterobacter cloacae P99
Yan, J.J.; Hsueh, P.R.; Lu, J.J.; Chan, F.Y.; Ko, W.C.; Wu, J.J.
Characterization of acquired beta-lactamases and their genetic support in multidrug-resistant Pseudomonas aeruginosa isolates in Taiwan: the prevalence of unusual integrons
J. Antimicrob. Chemother.
58
530-536
2006
Pseudomonas aeruginosa, Pseudomonas aeruginosa (Q27JM4), Pseudomonas aeruginosa (Q6QJ55), Pseudomonas aeruginosa (Q7BHJ5), Pseudomonas aeruginosa (Q9F629)
Tsakris, A.; Ikonomidis, A.; Spanakis, N.; Poulou, A.; Pournaras, S.
Characterization of In3Mor, a new integron carrying VIM-1 metallo-beta-lactamase and sat1 gene, from Morganella morganii
J. Antimicrob. Chemother.
59
739-741
2007
Morganella morganii, Morganella morganii A209
Beceiro, A.; Perez-Llarena, F.-J.; Perez, A.; Tomas, M.; Fernandez, A.; Mallo, S.; Villanueva, R.; Bou, G.
Molecular characterization of the gene encoding a new AmpC beta-lactamase in Acinetobacter baylyi
J. Antimicrob. Chemother.
59
996-1000
2007
Acinetobacter baylyi (Q0VJU2), Acinetobacter baylyi
Bhattacharjee, A.; Sen, M.R.; Prakash, P.; Anupurba, S.
Role of beta-lactamase inhibitors in enterobacterial isolates producing extended-spectrum beta-lactamases
J. Antimicrob. Chemother.
61
309-314
2008
Escherichia coli, Klebsiella sp., Proteus mirabilis
Yamaguchi, Y.; Jin, W.; Matsunaga, K.; Ikemizu, S.; Yamagata, Y.; Wachino, J.; Shibata, N.; Arakawa, Y.; Kurosaki, H.
Crystallographic investigation of the inhibition mode of a VIM-2 metallo-beta-lactamase from Pseudomonas aeruginosa by a mercaptocarboxylate inhibitor
J. Med. Chem.
50
6647-6653
2007
Pseudomonas aeruginosa
Nauton, L.; Kahn, R.; Garau, G.; Hernandez, J.F.; Dideberg, O.
Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia
J. Mol. Biol.
375
257-269
2008
Stenotrophomonas maltophilia (P52700), Stenotrophomonas maltophilia
Zhao, W.H.; Hu, Z.Q.; Chen, G.; Matsushita, K.; Fukuchi, K.; Shimamura, T.
Characterization of imipenem-resistant Serratia marcescens producing IMP-type and TEM-type beta-lactamases encoded on a single plasmid
Microbiol. Res.
162
46-52
2007
Serratia marcescens
de Castillo, M.C.; Islas, M.I.; de Nader, O.M.; de Ruiz-Holgado, A.P.
Purification and characterization of beta-lactamase from Neisseria gonorrhoeae from clinical samples
Rev. Latinoam. Microbiol.
43
70-75
2006
Neisseria gonorrhoeae
Garza-Ramos, U.; Morfin-Otero, R.; Sader, H.S.; Jones, R.N.; Hernndez, E.; Rodriguez-Noriega, E.; Sanchez, A.; Carrillo, B.; Esparza-Ahumada, S.; Silva-Sanchez, J.
Metallo-beta-lactamase gene bla(IMP-15) in a class 1 integron, In95, from Pseudomonas aeruginosa clinical isolates from a hospital in Mexico
Antimicrob. Agents Chemother.
52
2943-2946
2008
Pseudomonas aeruginosa, Pseudomonas aeruginosa (Q53CM3), Pseudomonas aeruginosa (Q7AYX1)
Li, H.; Toleman, M.A.; Bennett, P.M.; Jones, R.N.; Walsh, T.R.
Complete Sequence of p07-406, a 24,179-base-pair plasmid harboring the blaVIM-7 metallo-beta-lactamase gene in a Pseudomonas aeruginosa isolate from the United States
Antimicrob. Agents Chemother.
52
3099-3105
2008
Pseudomonas aeruginosa (Q840P9), Pseudomonas aeruginosa
Juan, C.; Beceiro, A.; Gutirrez, O.; Albert, S.; Garau, M.; Prez, J.L.; Bou, G.; Oliver, A.
Characterization of the new metallo-beta-lactamase VIM-13 and its integron-borne gene from a Pseudomonas aeruginosa clinical isolate in Spain
Antimicrob. Agents Chemother.
52
3589-3596
2008
Pseudomonas aeruginosa, Pseudomonas aeruginosa (Q2HY42), Pseudomonas aeruginosa (Q9XAY4), Pseudomonas aeruginosa SL2 (Q2HY42), Pseudomonas aeruginosa SL2 (Q9XAY4)
Takeda, S.; Nakai, T.; Ikeda, F.; Hatano, K.
Overproduction of a metallo-beta-lactamase by a strong promoter causes high-level imipenem resistance in a clinical isolate of Pseudomonas aeruginosa
Chemotherapy
54
181-187
2008
Pseudomonas aeruginosa (Q7DH52), Pseudomonas aeruginosa
Bedenic, B.; Vranes, J.; Sviben, M.; Beader, N.; Kalenic, S.
Postantibiotic and post-beta-lactamase inhibitor effect of carbapenems combined with EDTA against Pseudomonas aeruginosa strains producing VIM-metallo beta-lactamases
Chemotherapy
54
188-193
2008
Pseudomonas aeruginosa
Edalucci, E.; Spinelli, R.; Dolzani, L.; Riccio, M.L.; Dubois, V.; Tonin, E.A.; Rossolini, G.M.; Lagatolla, C.
Acquisition of different carbapenem resistance mechanisms by an epidemic clonal lineage of Pseudomonas aeruginosa
Clin. Microbiol. Infect.
14
88-90
2008
Pseudomonas aeruginosa, Pseudomonas aeruginosa (Q7BHJ5)
Motoshima, M.; Yanagihara, K.; Yamamoto, K.; Morinaga, Y.; Matsuda, J.; Sugahara, K.; Hirakata, Y.; Yamada, Y.; Kohno, S.; Kamihira, S.
Quantitative detection of metallo-beta-lactamase of blaIMP-cluster-producing Pseudomonas aeruginosa by real-time polymerase chain reaction with melting curve analysis for rapid diagnosis and treatment of nosocomial infection
Diagn. Microbiol. Infect. Dis.
61
222-226
2008
Pseudomonas aeruginosa (Q79MP6), Pseudomonas aeruginosa, Pseudomonas aeruginosa blaIMP-cluster-producing (Q79MP6)
Falagas, M.E.; Kanellopoulou, M.D.; Karageorgopoulos, D.E.; Dimopoulos, G.; Rafailidis, P.I.; Skarmoutsou, N.D.; Papafrangas, E.A.
Antimicrobial susceptibility of multidrug-resistant Gram negative bacteria to fosfomycin
Eur. J. Clin. Microbiol. Infect. Dis.
27
439-443
2008
Pseudomonas aeruginosa
Pena, A.; Donato, A.M.; Alves, A.F.; Leito, R.; Cardoso, O.M.
Detection of Pseudomonas aeruginosa producing metallo-beta-lactamase VIM-2 in a central hospital from Portugal
Eur. J. Clin. Microbiol. Infect. Dis.
27
1269-1271
2008
Pseudomonas aeruginosa
Cardoso, O.; Alves, A.F.; Leitao, R.
Metallo-beta-lactamase VIM-2 in Pseudomonas aeruginosa isolates from a cystic fibrosis patient
Int. J. Antimicrob. Agents
31
375-379
2008
Pseudomonas aeruginosa
Chao, Z.; Xiao-Feng, W.; Dan-Hong, S.; Jin-Ping, Y.; Nan-Shan, Z.
Outbreak of Pseudomonas aeruginosa producing IMP-9-type metallo-beta-lactamase in Guangzhou, China
Int. J. Antimicrob. Agents
32
363-365
2008
Pseudomonas aeruginosa (P14489), Pseudomonas aeruginosa
Miyajima, Y.; Hiramatsu, K.; Mizukami, E.; Morinaga, R.; Ishii, H.; Shirai, R.; Kishi, K.; Tokimatsu, I.; Saikawa, T.; Kadota, J.
In vitro and in vivo potency of polymyxin B against IMP-type metallo-beta-lactamase-producing Pseudomonas aeruginosa
Int. J. Antimicrob. Agents
32
437-440
2008
Pseudomonas aeruginosa
Koh, T.H.; Yamaguchi, K.; Ishii, Y.
Characterisation of the metallo-beta-lactamase VIM-6 and its genetic support
Int. J. Antimicrob. Agents
32
446-449
2008
Pseudomonas putida (Q8GCU7), Pseudomonas putida
Yakupogullari, Y.; Poirel, L.; Bernabeu, S.; Kizirgil, A.; Nordmann, P.
Multidrug-resistant Pseudomonas aeruginosa isolate co-expressing extended-spectrum beta-lactamase PER-1 and metallo-beta-lactamase VIM-2 from Turkey
J. Antimicrob. Chemother.
61
221-222
2008
Pseudomonas aeruginosa
Samuelsen, O.; Buar, L.; Giske, C.G.; Simonsen, G.S.; Aasnaes, B.; Sundsfjord, A.
Evaluation of phenotypic tests for the detection of metallo-beta-lactamase-producing Pseudomonas aeruginosa in a low prevalence country
J. Antimicrob. Chemother.
61
827-830
2008
Pseudomonas aeruginosa
Dubois, V.; Arpin, C.; Dupart, V.; Scavelli, A.; Coulange, L.; Andr, C.; Fischer, I.; Grobost, F.; Brochet, J.P.; Lagrange, I.; Dutilh, B.; Jullin, J.; Noury, P.; Larribet, G.; Quentin, C.
Beta-lactam and aminoglycoside resistance rates and mechanisms among Pseudomonas aeruginosa in French general practice (community and private healthcare centres)
J. Antimicrob. Chemother.
62
316-323
2008
Pseudomonas aeruginosa
Kim, J.Y.; Park, Y.J.; Kwon, H.J.; Han, K.; Kang, M.W.; Woo, G.J.
Occurrence and mechanisms of amikacin resistance and its association with beta-lactamases in Pseudomonas aeruginosa: a Korean nationwide study
J. Antimicrob. Chemother.
62
479-483
2008
Pseudomonas aeruginosa
Picao, R.C.; Andrade, S.S.; Nicoletti, A.G.; Campana, E.H.; Moraes, G.C.; Mendes, R.E.; Gales, A.C.
Metallo-beta-Lactamase detection: comparative evaluation of double-disk synergy versus combined disk tests for IMP, GIM, SIM, SPM or VIM-producing isolates
J. Clin. Microbiol.
46
2028-2037
2008
Acinetobacter sp., Enterobacter cloacae, Klebsiella pneumoniae, Pseudomonas aeruginosa, Pseudomonas putida, Serratia marcescens
Cheng, X.; Wang, P.; Wang, Y.; Zhang, H.; Tao, C.; Yang, W.; Liu, M.; Jia, W.
Identification and distribution of the clinical isolates of imipenem-resistant Pseudomonas aeruginosa carrying metallo-beta-lactamase and/or class 1 integron genes
J. Huazhong Univ. Sci. Technol. Med. Sci.
28
235-238
2008
Pseudomonas aeruginosa
Tsuchimochi, N.; Takuma, T.; Shimono, N.; Nagasaki, Y.; Uchida, Y.; Harada, M.
Antimicrobial susceptibility and molecular epidemiological analysis of clinical strains of Pseudomonas aeruginosa
J. Infect. Chemother.
14
99-104
2008
Pseudomonas aeruginosa
Garcia-Saez, I.; Docquier, J.D.; Rossolini, G.M.; Dideberg, O.
The three-dimensional structure of VIM-2, a Zn-beta-lactamase from Pseudomonas aeruginosa in its reduced and oxidised form
J. Mol. Biol.
375
604-611
2008
Pseudomonas aeruginosa (Q9K2N0), Pseudomonas aeruginosa
David, M.; Lemeland, J.F.; Boyer, S.
Emergence of extended-spectrum beta-lactamases in Pseudomonas aeruginosa: about 24 cases at Rouen university hospital
Pathol. Biol.
56
429-434
2008
Pseudomonas aeruginosa
Kalai Blagui, S.; Achour, W.; Abdeladhim, A.; Ben Hassen, A.
Identification of SHV-type extended spectrum beta-lactamase genes in Pseudomonas aeruginosa by PCR-restriction fragment length polymorphism and insertion site restriction-PCR.
Pathol. Biol.
57
420-424
2008
Pseudomonas aeruginosa
Sevillano, E.; Gallego, L.; Garca-Lobo, J.M.
First detection of the OXA-40 carbapenemase in P. aeruginosa isolates, located on a plasmid also found in A. baumannii
Pathol. Biol.
57
493-495
2008
Pseudomonas aeruginosa
Kalai Blagui, S.; Achour, W.; Bejaoui, M.; Abdeladhim, A.; Ben Hassen, A.
Detection of SHV-1 beta-lactamase in Pseudomonas aeruginosa strains by genetic methods
Pathol. Biol.
57
e73-e75
2008
Pseudomonas aeruginosa
Kim, S.; Joo, S.; Yoon, S.; Kim, S.; Moon, J.; Ryu, Y.; Kim, K.K.; Kim, T.D.
Purification, crystallization and preliminary crystallographic analysis of Est-Y29: a novel oligomeric beta-lactamase
Acta Crystallogr. Sect. F
65
310-312
2009
Bacteria
Hu, R.; Huang, K.; Wu, L.; Hsiao, Y.; Yang, T.
Induction of L1 and L2 beta -lactamases of Stenotrophomonas maltophilia
Antimicrob. Agents Chemother.
52
1198-1200
2008
Stenotrophomonas maltophilia (B1NLE9), Stenotrophomonas maltophilia (Q9RBQ1), Stenotrophomonas maltophilia KJ (B1NLE9), Stenotrophomonas maltophilia KJ (Q9RBQ1)
Mendonca, N.; Manageiro, V.; Bonnet, R.; Canica, M.
Biochemical characterization of SHV-55, an extended-spectrum class a beta -lactamase from Klebsiella pneumoniae
Antimicrob. Agents Chemother.
52
1897-1898
2008
Klebsiella pneumoniae (Q4TVR4), Klebsiella pneumoniae
Stoczko, M.; Frere, J.; Rossolini, G.M.; Docquier, J.
Functional diversity among metallo-beta -lactamases: characterization of the CAR-1 enzyme of Erwinia carotovora
Antimicrob. Agents Chemother.
52
2473-2479
2008
Pectobacterium carotovorum (Q6D395), Pectobacterium carotovorum
Samuelsen, O.; Castanheira, M.; Walsh, T.R.; Spencer, J.
Kinetic characterization of VIM-7, a divergent member of the VIM metallo-beta -lactamase family
Antimicrob. Agents Chemother.
52
2905-2908
2008
Pseudomonas aeruginosa (Q840P9)
Sekiguchi, J.; Morita, K.; Kitao, T.; Watanabe, N.; Okazaki, M.; Miyoshi-Akiyama, T.; Kanamori, M.; Kirikae, T.
KHM-1, a novel plasmid-mediated metallo-beta -lactamase from a Citrobacter freundii clinical isolate
Antimicrob. Agents Chemother.
52
4194-4197
2008
Citrobacter freundii (A8R403), Citrobacter freundii
Perilli, M.; Celenza, G.; De Santis, F.; Pellegrini, C.; Forcella, C.; Rossolini, G.M.; Stefani, S.; Amicosante, G.
E240V substitution increases catalytic efficiency toward ceftazidime in a new natural TEM-type extended-spectrum beta -lactamase, TEM-149, from Enterobacter aerogenes and Serratia marcescens clinical isolates
Antimicrob. Agents Chemother.
52
915-919
2008
Klebsiella aerogenes (Q1KY81), Klebsiella aerogenes, Klebsiella aerogenes SS-13 (Q1KY81)
Mammeri, H.; Galleni, M.; Nordmann, P.
Role of the Ser-287-Asn replacement in the hydrolysis spectrum extension of AmpC beta -lactamases in Escherichia coli
Antimicrob. Agents Chemother.
53
323-326
2009
Escherichia coli (P00811), Escherichia coli
Nagano, Y.; Nagano, N.; Wachino, J.; Ishikawa, K.; Arakawa, Y.
Novel chimeric beta -lactamase CTX-M-64, a hybrid of CTX-M-15-like and CTX-M-14 beta -lactamases, found in a Shigella sonnei strain resistant to various oxyimino-cephalosporins, including ceftazidime
Antimicrob. Agents Chemother.
53
69-74
2009
Shigella sonnei (A5LH21), Shigella sonnei, Shigella sonnei UIH-1 (A5LH21)
Poirel, L.; Rodriguez-Martinez, J.; Plesiat, P.; Nordmann, P.
Naturally occurring class A beta -lactamases from the Burkholderia cepacia complex
Antimicrob. Agents Chemother.
53
876-882
2009
Burkholderia cenocepacia (B8R6A5), Burkholderia cenocepacia (C1J897), Burkholderia cenocepacia (C1J899), Burkholderia cenocepacia (C1J8A0)
Leonard, D.A.; Hujer, A.M.; Smith, B.A.; Schneider, K.D.; Bethel, C.R.; Hujer, K.M.; Bonomo, R.A.
The role of OXA-1 beta -lactamase Asp66 in the stabilization of the active-site carbamate group and in substrate turnover
Biochem. J.
410
455-462
2008
Escherichia coli (P13661)
Bebrone, C.; Anne, C.; Kerff, F.; Garau, G.; De Vriendt, K.; Lantin, R.; Devreese, B.; Van Beeumen, J.; Dideberg, O.; Frere, J.; Galleni, M.
Mutational analysis of the zinc- and substrate-binding sites in the CphA metallo-beta -lactamase from Aeromonas hydrophila
Biochem. J.
414
151-159
2008
Aeromonas hydrophila (P26918), Aeromonas hydrophila
Lejeune, A.; Pain, R.H.; Charlier, P.; Frere, J.; Matagne, A.
TEM-1 beta -lactamase folds in a nonhierarchical manner with transient non-native interactions involving the C-terminal region
Biochemistry
47
1186-1193
2008
Escherichia coli, Escherichia coli RB791
Pelto, R.B.; Pratt, R.F.
Kinetics and mechanism of inhibition of a serine beta -lactamase by O-aryloxycarbonyl hydroxamates
Biochemistry
47
12037-12046
2008
Enterobacter cloacae, Enterobacter cloacae P99
Adediran, S.A.; Pratt, R.F.
Inhibition of serine beta -lactamases by vanadate-catechol complexes
Biochemistry
47
9467-9474
2008
Escherichia coli, Enterobacter cloacae (P05364), Enterobacter cloacae P99 (P05364)
Hu, Z.; Spadafora, L.J.; Hajdin, C.E.; Bennett, B.; Crowder, M.W.
Structure and mechanism of copper- and nickel-substituted analogues of metallo-beta -lactamase L1
Biochemistry
48
2981-2989
2009
Escherichia coli
Perumal, S.K.; Adediran, S.A.; Pratt, R.F.
beta -Ketophosphonates as beta -lactamase inhibitors: Intramolecular cooperativity between the hydrophobic subsites of a class D beta -lactamase
Bioorg. Med. Chem.
16
6987-6994
2008
Enterobacter cloacae (Q59401), Enterobacter cloacae P99 (Q59401), Enterobacter cloacae P99, Escherichia coli, Escherichia coli (P13661), Escherichia coli (P62593)
Wang, Q.; Cheng, J.; Chen, Y.; Ye, Y.; Li, J.; Zhang, X.
Characterization of a novel AmpC-type plasmid-mediated beta -lactamase from an Escherichia coli strain isolated in China
Curr. Microbiol.
57
558-563
2008
Escherichia coli (A3RIY0), Escherichia coli, Escherichia coli E384 (A3RIY0), Escherichia coli E384
Ahmed, A.M.; Shimamoto, T.
Emergence of a cefepime- and cefpirome-resistant Citrobacter freundii clinical isolate harbouring a novel chromosomally encoded AmpC beta -lactamase, CMY-37
Int. J. Antimicrob. Agents
32
256-261
2008
Citrobacter freundii, Citrobacter freundii 4306
Chen, Y.; Cheng, J.; Wang, Q.; Ye, Y.; Li, J.; Zhang, X.
ACT-3, a novel plasmid-encoded class C beta -lactamase in a Klebsiella pneumoniae isolate from China
Int. J. Antimicrob. Agents
33
95-96
2009
Klebsiella pneumoniae (A1EGT8), Klebsiella pneumoniae
Hu, Z.; Periyannan, G.; Bennett, B.; Crowder, M.W.
Role of the Zn1 and Zn2 sites in Metallo-beta -lactamase L1
J. Am. Chem. Soc.
130
14207-14216
2008
Stenotrophomonas maltophilia (P52700)
Llarrull, L.I.; Tioni, M.F.; Vila, A.J.
Metal Content and Localization during Turnover in B. cereus Metallo-beta -lactamase
J. Am. Chem. Soc.
130
15842-15851
2008
Bacillus cereus (P04190)
Sharma, N.; Hu, Z.; Crowder, M.W.; Bennett, B.
Conformational changes in the metallo-beta -lactamase ImiS during the catalytic reaction: An EPR spectrokinetic study of Co(II)-spin label interactions
J. Am. Chem. Soc.
130
8215-8222
2008
Aeromonas veronii bv. sobria (O31272)
Perez-Llarena, F.J.; Cartelle, M.; Mallo, S.; Beceiro, A.; Perez, A.; Villanueva, R.; Romero, A.; Bonnet, R.; Bou, G.
Structure-function studies of arginine at position 276 in CTX-M beta -lactamases
J. Antimicrob. Chemother.
61
792-797
2008
Escherichia coli (P28585), Escherichia coli
Badarau, A.; Page, M.I.
Loss of enzyme activity during turnover of the Bacillus cereus beta -lactamase catalyzed hydrolysis of beta -lactams due to loss of zinc ion
J. Biol. Inorg. Chem.
13
919-928
2008
Bacillus cereus (P04190), Bacillus cereus, Bacillus cereus 569/H/9 (P04190)
Fenollar-Ferrer, C.; Frau, J.; Donoso, J.; Munoz, F.
Evolution of class C beta -lactamases: factors influencing their hydrolysis and recognition mechanisms
Theor. Chem. Acc.
121
209-218
2008
Enterobacter cloacae, Enterobacter cloacae P99
-
Shimamura, T.; Nitanai, Y.; Uchiyama, T.; Matsuzawa, H.
Improvement of crystal quality by surface mutations of beta-lactamase Toho-1
Acta Crystallogr. Sect. F
65
379-382
2009
Escherichia coli (Q47066)
Drawz, S.M.; Bethel, C.R.; Doppalapudi, V.R.; Sheri, A.; Pagadala, S.R.; Hujer, A.M.; Skalweit, M.J.; Anderson, V.E.; Chen, S.G.; Buynak, J.D.; Bonomo, R.A.
Penicillin sulfone inhibitors of class D beta-lactamases
Antimicrob. Agents Chemother.
54
1414-1424
2010
Acinetobacter sp., Pseudomonas aeruginosa, plasmid RGN238
De Luca, F.; Giraud-Morin, C.; Rossolini, G.M.; Docquier, J.D.; Fosse, T.
Genetic and biochemical characterization of TRU-1, the endogenous class C beta-lactamase from Aeromonas enteropelogenes
Antimicrob. Agents Chemother.
54
1547-1554
2010
Aeromonas enteropelogenes (B2BSN6), Aeromonas enteropelogenes
Papp-Wallace, K.M.; Taracila, M.; Hornick, J.M.; Hujer, A.M.; Hujer, K.M.; Distler, A.M.; Endimiani, A.; Bonomo, R.A.
Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase
Antimicrob. Agents Chemother.
54
2867-2877
2010
plasmid pBC
Bent, Z.W.; Young, G.M.
Contribution of BlaA and BlaB beta-lactamases to antibiotic susceptibility of Yersinia enterocolitica biovar 1B
Antimicrob. Agents Chemother.
54
4000-4002
2010
Yersinia enterocolitica
Doublet, B.; Robin, F.; Casin, I.; Fabre, L.; Le Fleche, A.; Bonnet, R.; Weill, F.X.
Molecular and biochemical characterization of the natural chromosome-encoded class A beta-lactamase from Pseudomonas luteola
Antimicrob. Agents Chemother.
54
45-51
2010
Pseudomonas luteola (Q670S6), Pseudomonas luteola
Baurin, S.; Vercheval, L.; Bouillenne, F.; Falzone, C.; Brans, A.; Jacquamet, L.; Ferrer, J.L.; Sauvage, E.; Dehareng, D.; Frere, J.M.; Charlier, P.; Galleni, M.; Kerff, F.
Critical role of tryptophan 154 for the activity and stability of class D beta-lactamases
Biochemistry
48
11252-11263
2009
plasmid pGEM-T-easy
Schneider, K.D.; Karpen, M.E.; Bonomo, R.A.; Leonard, D.A.; Powers, R.A.
The 1.4 A crystal structure of the class D beta-lactamase OXA-1 complexed with doripenem
Biochemistry
48
11840-11847
2009
Acinetobacter baumannii
Drawz, S.M.; Bethel, C.R.; Hujer, K.M.; Hurless, K.N.; Distler, A.M.; Caselli, E.; Prati, F.; Bonomo, R.A.
The role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276
Biochemistry
48
4557-4566
2009
synthetic construct
Hanes, M.S.; Jude, K.M.; Berger, J.M.; Bonomo, R.A.; Handel, T.M.
Structural and biochemical characterization of the interaction between KPC-2 beta-lactamase and beta-lactamase inhibitor protein
Biochemistry
48
9185-9193
2009
pBR322 based IG-lambda expression vector
Tremblay, L.W.; Fan, F.; Blanchard, J.S.
Biochemical and structural characterization of Mycobacterium tuberculosis beta-lactamase with the carbapenems ertapenem and doripenem
Biochemistry
49
3766-3773
2010
Mycobacterium tuberculosis (P9WKD3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WKD3)
Ganta, S.R.; Perumal, S.; Pagadala, S.R.; Samuelsen, O.; Spencer, J.; Pratt, R.F.; Buynak, J.D.
Approaches to the simultaneous inactivation of metallo- and serine-beta-lactamases
Bioorg. Med. Chem. Lett.
19
1618-1622
2009
Enterobacter cloacae, Escherichia coli
Hiraiwa, Y.; Morinaka, A.; Fukushima, T.; Kudo, T.
Metallo-beta-lactamase inhibitory activity of phthalic acid derivatives
Bioorg. Med. Chem. Lett.
19
5162-5165
2009
Pseudomonas aeruginosa
Docquier, J.D.; Calderone, V.; De Luca, F.; Benvenuti, M.; Giuliani, F.; Bellucci, L.; Tafi, A.; Nordmann, P.; Botta, M.; Rossolini, G.M.; Mangani, S.
Crystal structure of the OXA-48 beta-lactamase reveals mechanistic diversity among class D carbapenemases
Chem. Biol.
16
540-547
2009
Klebsiella pneumoniae (Q6XEC0)
Sauvage, E.; Zervosen, A.; Dive, G.; Herman, R.; Amoroso, A.; Joris, B.; Fonze, E.; Pratt, R.F.; Luxen, A.; Charlier, P.; Kerff, F.
Structural basis of the inhibition of class A beta-lactamases and penicillin-binding proteins by 6-beta-iodopenicillanate
J. Am. Chem. Soc.
131
15262-15269
2009
Bacillus subtilis
Brown, N.G.; Shanker, S.; Prasad, B.V.; Palzkill, T.
Structural and biochemical evidence that a TEM-1 beta-lactamase N170G active site mutant acts via substrate-assisted catalysis
J. Biol. Chem.
284
33703-33712
2009
plasmid pBG66
Wang, J.; Palzkill, T.; Chow, D.
Structural insight into the kinetics and DELTACp of interactions between TEM-1 beta-lactamase and beta-lactamase inhibitory protein (BLIP)
J. Biol. Chem.
284
595-609
2009
Escherichia coli (P62593)
Brown, T.; Charlier, P.; Herman, R.; Schofield, C.J.; Sauvage, E.
Structural basis for the interaction of lactivicins with serine beta-lactamases
J. Med. Chem.
53
5890-5894
2010
Bacillus licheniformis (P94458)
Hu, R.M.; Chiang, K.H.; Chang, Y.C.; Yang, T.C.
Characterization of the charge variants of L2 beta-lactamase in Stenotrophomonas maltophilia
J. Med. Microbiol.
58
318-321
2009
Stenotrophomonas maltophilia (B5KLI1), Stenotrophomonas maltophilia
De Wals, P.Y.; Doucet, N.; Pelletier, J.N.
High tolerance to simultaneous active-site mutations in TEM-1 beta-lactamase: Distinct mutational paths provide more generalized beta-lactam recognition
Protein Sci.
18
147-160
2009
plasmid pQE32Chl17
Risso, V.A.; Primo, M.E.; Ermacora, M.R.
Re-engineering a beta-lactamase using prototype peptides from a library of local structural motifs
Protein Sci.
18
440-449
2009
Bacillus licheniformis (P00808), Bacillus licheniformis
Lassaux, P.; Traore, D.A.; Loisel, E.; Favier, A.; Docquier, J.D.; Sohier, J.S.; Laurent, C.; Bebrone, C.; Frere, J.M.; Ferrer, J.L.; Galleni, M.
Biochemical and structural characterization of the subclass B1 metallo-beta-lactamase VIM-4
Antimicrob. Agents Chemother.
55
1248-1255
2011
Pseudomonas aeruginosa (Q8KRJ3), Pseudomonas aeruginosa
Borgianni, L.; Prandi, S.; Salden, L.; Santella, G.; Hanson, N.D.; Rossolini, G.M.; Docquier, J.D.
Genetic context and biochemical characterization of the IMP-18 metallo-beta-lactamase identified in a Pseudomonas aeruginosa isolate from the United States
Antimicrob. Agents Chemother.
55
140-145
2011
Pseudomonas aeruginosa (Q5U807), Pseudomonas aeruginosa, Pseudomonas aeruginosa PS297 (Q5U807)
Santella, G.; Docquier, J.D.; Gutkind, G.; Rossolini, G.M.; Radice, M.
Purification and biochemical characterization of IMP-13 metallo-beta-lactamase
Antimicrob. Agents Chemother.
55
399-401
2011
Pseudomonas aeruginosa (Q7WYA8)
Fonseca, F.; Arthur, C.J.; Bromley, E.H.; Samyn, B.; Moerman, P.; Saavedra, M.J.; Correia, A.; Spencer, J.
Biochemical characterization of Sfh-I, a subclass B2 metallo-beta-lactamase from Serratia fonticola UTAD54
Antimicrob. Agents Chemother.
55
5392-5395
2011
Serratia fonticola (Q9RMI1), Serratia fonticola UTAD54 (Q9RMI1), Serratia fonticola UTAD54
Lee, K.; Yum, J.H.; Yong, D.; Jeong, S.H.; Rossolini, G.M.; Docquier, J.D.; Chong, Y.
Biochemical characterization of the TEM-107 extended-spectrum beta-lactamase in a Klebsiella pneumoniae isolate from South Korea
Antimicrob. Agents Chemother.
55
5930-5932
2011
Klebsiella pneumoniae (Q8KQ59), Klebsiella pneumoniae
El Salabi, A.; Borra, P.S.; Toleman, M.A.; Samuelsen, O.; Walsh, T.R.
Genetic and biochemical characterization of a novel metallo-beta-lactamase, TMB-1, from an Achromobacter xylosoxidans strain isolated in Tripoli, Libya
Antimicrob. Agents Chemother.
56
2241-2245
2012
Achromobacter sp. sallbros1 (E7BCS7)
Bonnin, R.A.; Ocampo-Sosa, A.A.; Poirel, L.; Guet-Revillet, H.; Nordmann, P.
Biochemical and genetic characterization of carbapenem-hydrolyzing beta-lactamase OXA-229 from Acinetobacter bereziniae
Antimicrob. Agents Chemother.
56
3923-3927
2012
Acinetobacter bereziniae (I6S7G0), Acinetobacter bereziniae
Matsumoto, T.; Nagata, M.; Ishimine, N.; Kawasaki, K.; Yamauchi, K.; Hidaka, E.; Kasuga, E.; Horiuchi, K.; Oana, K.; Kawakami, Y.; Honda, T.
Characterization of CIA-1, an Ambler class A extended-spectrum beta-lactamase from Chryseobacterium indologenes
Antimicrob. Agents Chemother.
56
588-590
2012
Chryseobacterium indologenes (G9M9P7), Chryseobacterium indologenes, Chryseobacterium indologenes ATCC 29897 (G9M9P7)
Pelto, R.B.; Pratt, R.F.
Serendipitous discovery of alpha-hydroxyalkyl esters as beta-lactamase substrates
Biochemistry
49
10496-10506
2010
Enterobacter cloacae (P05364)
Griffin, D.H.; Richmond, T.K.; Sanchez, C.; Moller, A.J.; Breece, R.M.; Tierney, D.L.; Bennett, B.; Crowder, M.W.
Structural and kinetic studies on metallo-beta-lactamase IMP-1
Biochemistry
50
9125-9134
2011
Serratia marcescens (P52699)
Tan, Q.; Ogawa, A.M.; Painter, R.E.; Park, Y.W.; Young, K.; DiNinno, F.P.
4,7-Dichloro benzothien-2-yl sulfonylaminomethyl boronic acid: first boronic acid-derived beta-lactamase inhibitor with class A, C, and D activity
Bioorg. Med. Chem. Lett.
20
2622-2624
2010
Klebsiella pneumoniae (P0A3M1), Pseudomonas aeruginosa (Q6LBN9), Acinetobacter baumannii (Q8RLA6), Acinetobacter baumannii
Adediran, S.; Cabaret, D.; Lohier, J.; Wakselman, M.; Pratt, R.
Substituted aryl malonamates as new serine beta-lactamase substrates: structure-activity studies
Bioorg. Med. Chem.
18
282-291
2010
Enterobacter cloacae (P05364)
Schlesinger, S.R.; Kim, S.G.; Lee, J.S.; Kim, S.K.
Purification development and characterization of the zinc-dependent metallo-beta-lactamase from Bacillus anthracis
Biotechnol. Lett.
33
1417-1422
2011
Bacillus anthracis
Mohamed, M.S.; Hussein, W.M.; McGeary, R.P.; Vella, P.; Schenk, G.; Abd El-Hameed, R.H.
Synthesis and kinetic testing of new inhibitors for a metallo-beta-lactamase from Klebsiella pneumonia and Pseudomonas aeruginosa
Eur. J. Med. Chem.
46
6075-6082
2011
Klebsiella pneumoniae
Wong, W.T.; Chan, K.C.; So, P.K.; Yap, H.K.; Chung, W.H.; Leung, Y.C.; Wong, K.Y.; Zhao, Y.
Increased structural flexibility at the active site of a fluorophore-conjugated beta-lactamase distinctively impacts its binding toward diverse cephalosporin antibiotics
J. Biol. Chem.
286
31771-31780
2011
Bacillus licheniformis (P00808)
Eidam, O.; Romagnoli, C.; Caselli, E.; Babaoglu, K.; Pohlhaus, D.T.; Karpiak, J.; Bonnet, R.; Shoichet, B.K.; Prati, F.
Design, synthesis, crystal structures, and antimicrobial activity of sulfonamide boronic acids as beta-lactamase inhibitors
J. Med. Chem.
53
7852-7863
2010
Escherichia coli (P00811)
Borra, P.S.; Leiros, H.K.; Ahmad, R.; Spencer, J.; Leiros, I.; Walsh, T.R.; Sundsfjord, A.; Samuelsen, O.
Structural and computational investigations of VIM-7: insights into the substrate specificity of vim metallo-beta-lactamases
J. Mol. Biol.
411
174-189
2011
Pseudomonas aeruginosa (Q840P9), Pseudomonas aeruginosa
Guntas, G.; Kanwar, M.; Ostermeier, M.
Circular permutation in the omega-loop of TEM-1 beta-lactamase results in improved activity and altered substrate specificity
PLoS ONE
7
e35998
2012
Escherichia coli (P62593)
Yi, H.; Cho, K.H.; Cho, Y.S.; Kim, K.; Nierman, W.C.; Kim, H.S.
Twelve Positions in a beta-lactamase that can expand its substrate spectrum with a single amino acid substitution
PLoS ONE
7
e37585
2012
Burkholderia thailandensis
Ke, W.; Laurent, A.H.; Armstrong, M.D.; Chen, Y.; Smith, W.E.; Liang, J.; Wright, C.M.; Ostermeier, M.; van den Akker, F.
Structure of an engineered beta-lactamase maltose binding protein fusion protein: insights into heterotropic allosteric regulation
PLoS ONE
7
e39168
2012
Escherichia coli (P62593)
Mathieu, V.; Fastrez, J.; Soumillion, P.
Engineering allosteric regulation into the hinge region of a circularly permuted TEM-1 beta-lactamase
Protein Eng. Des. Sel.
23
699-709
2010
Escherichia coli
Shimada, A.; Ishikawa, H.; Nakagawa, N.; Kuramitsu, S.; Masui, R.
The first crystal structure of an archaeal metallo-beta-lactamase superfamily protein; ST1585 from Sulfolobus tokodaii
Proteins Struct. Funct. Bioinform.
78
2399-2402
2010
Sulfurisphaera tokodaii (Q970L2), Sulfurisphaera tokodaii
Hanes, M.; Reynolds, K.; Mcnamara, C.; Ghosh, P.; Bonomo, R.; Kirsch, J.; Handel, T.
Specificity and cooperativity at beta-lactamase position 104 in TEM-1/BLIP and SHV-1/BLIP interactions
Proteins Struct. Funct. Bioinform.
79
1267-1276
2011
Klebsiella pneumoniae (P0AD64)
Wachino, J.; Yamaguchi, Y.; Mori, S.; Yamagata, Y.; Arakawa, Y.; Shibayama, K.
Crystallization and preliminary X-ray analysis of the subclass B3 metallo-beta-lactamase SMB-1 that confers carbapenem resistance
Acta Crystallogr. Sect. F
68
343-346
2012
Serratia marcescens
Oguri, T.; Furuyama, T.; Okuno, T.; Ishii, Y.; Tateda, K.; Bonomo, R.A.; Shimizu-Ibuka, A.
Crystal structure of Mox-1, a unique plasmid-mediated class C beta-lactamase with hydrolytic activity towards moxalactam
Antimicrob. Agents Chemother.
58
3914-3920
2014
Klebsiella pneumoniae (Q51578), Klebsiella pneumoniae NU2936 (Q51578)
Ruggiero, M.; Kerff, F.; Herman, R.; Sapunaric, F.; Galleni, M.; Gutkind, G.; Charlier, P.; Sauvage, E.; Power, P.
Crystal structure of the extended-spectrum beta-lactamase PER-2 and insights into the role of specific residues in the interaction with beta-lactams and beta-lactamase inhibitors
Antimicrob. Agents Chemother.
58
5994-6002
2014
Salmonella enterica
Hwang, J.; Cho, K.H.; Song, H.; Yi, H.; Kim, H.S.
Deletion mutations conferring substrate spectrum extension in the class A beta-lactamase
Antimicrob. Agents Chemother.
58
6265-6269
2014
Burkholderia thailandensis
Borgianni, L.; De Luca, F.; Thaller, M.C.; Chong, Y.; Rossolini, G.M.; Docquier, J.D.
Biochemical characterization of the POM-1 metallo-beta-lactamase from Pseudomonas otitidis
Antimicrob. Agents Chemother.
59
1755-1758
2015
Pseudomonas otitidis (E6Y3G9), Pseudomonas otitidis
Xu, H.; Hazra, S.; Blanchard, J.S.
NXL104 irreversibly inhibits the beta-lactamase from Mycobacterium tuberculosis
Biochemistry
51
4551-4557
2012
Mycobacterium tuberculosis
Chow, C.; Xu, H.; Blanchard, J.S.
Kinetic characterization of hydrolysis of nitrocefin, cefoxitin, and meropenem by beta-lactamase from Mycobacterium tuberculosis
Biochemistry
52
4097-4104
2013
Mycobacterium tuberculosis (P9WKD3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WKD3)
Hazra, S.; Xu, H.; Blanchard, J.S.
Tebipenem, a new carbapenem antibiotic, is a slow substrate that inhibits the beta-lactamase from Mycobacterium tuberculosis
Biochemistry
53
3671-3678
2014
Mycobacterium tuberculosis (P9WKD3), Mycobacterium tuberculosis H37Rv (P9WKD3)
Aitha, M.; Marts, A.R.; Bergstrom, A.; Moeller, A.J.; Moritz, L.; Turner, L.; Nix, J.C.; Bonomo, R.A.; Page, R.C.; Tierney, D.L.; Crowder, M.W.
Biochemical, mechanistic, and spectroscopic characterization of metallo-beta-lactamase VIM-2
Biochemistry
53
7321-7331
2014
Pseudomonas aeruginosa (Q9K2N0)
Stewart, N.K.; Smith, C.A.; Frase, H.; Black, D.J.; Vakulenko, S.B.
Kinetic and structural requirements for carbapenemase activity in GES-type beta-lactamases
Biochemistry
54
588-597
2015
Pseudomonas aeruginosa (A0EL75), Pseudomonas aeruginosa (Q7BEB3), Pseudomonas aeruginosa (Q93F76)
Yamaguchi, Y.; Matsueda, S.; Matsunaga, K.; Takashio, N.; Toma-Fukai, S.; Yamagata, Y.; Shibata, N.; Wachino, J.; Shibayama, K.; Arakawa, Y.; Kurosaki, H.
Crystal structure of IMP-2 metallo-beta-lactamase from Acinetobacter spp.: comparison of active-site loop structures between IMP-1 and IMP-2
Biol. Pharm. Bull.
38
96-101
2015
Acinetobacter baumannii (Q9KVZ2)
Zhang, Y.L.; Yang, K.W.; Zhou, Y.J.; LaCuran, A.E.; Oelschlaeger, P.; Crowder, M.W.
Diaryl-substituted azolylthioacetamides: Inhibitor discovery of New Delhi metallo-beta-lactamase-1 (NDM-1)
ChemMedChem
9
2445-2448
2014
Aeromonas veronii, Aeromonas veronii (O31272), Stenotrophomonas maltophilia (E9RIT0), Stenotrophomonas maltophilia, Bacteroides fragilis (P25910), Bacteroides fragilis
Papp-Wallace, K.M.; Mallo, S.; Bethel, C.R.; Taracila, M.A.; Hujer, A.M.; Fernandez, A.; Gatta, J.A.; Smith, K.M.; Xu, Y.; Page, M.G.; Desarbre, E.; Bou, G.; Bonomo, R.A.
A kinetic analysis of the inhibition of FOX-4 beta-lactamase, a plasmid-mediated AmpC cephalosporinase, by monocyclic beta-lactams and carbapenems
J. Antimicrob. Chemother.
69
682-690
2014
Escherichia coli
Dubee, V.; Bernut, A.; Cortes, M.; Lesne, T.; Dorchene, D.; Lefebvre, A.L.; Hugonnet, J.E.; Gutmann, L.; Mainardi, J.L.; Herrmann, J.L.; Gaillard, J.L.; Kremer, L.; Arthur, M.
beta-Lactamase inhibition by avibactam in Mycobacterium abscessus
J. Antimicrob. Chemother.
70
1051-1058
2015
Mycobacteroides abscessus (B1MM83), Mycobacteroides abscessus, Mycobacteroides abscessus CIP 104536 (B1MM83)
Makena, A.; Brem, J.; Pfeffer, I.; Geffen, R.E.; Wilkins, S.E.; Tarhonskaya, H.; Flashman, E.; Phee, L.M.; Wareham, D.W.; Schofield, C.J.
Biochemical characterization of New Delhi metallo-beta-lactamase variants reveals differences in protein stability
J. Antimicrob. Chemother.
70
463-469
2015
Escherichia coli (A0A024FRL9), Escherichia coli (A0A0F6N6D4), Escherichia coli (H6WET3), Escherichia coli (H6WZS9), Escherichia coli (I3VKD5), Escherichia coli (J7I0S9), Escherichia coli (M1VE66), Klebsiella pneumoniae (C7C422), Klebsiella pneumoniae (S5ZIP8), Klebsiella pneumoniae (T2A6Y2), Acinetobacter baumannii (F2YZ26)
Kristiansen, A.; Grgic, M.; Altermark, B.; Leiros, I.
Properties and distribution of a metallo-beta-lactamase (ALI-1) from the fish pathogen Aliivibrio salmonicida LFI1238
J. Antimicrob. Chemother.
70
766-772
2015
Aliivibrio salmonicida (B6EPH0)
Che, T.; Bethel, C.R.; Pusztai-Carey, M.; Bonomo, R.A.; Carey, P.R.
The different inhibition mechanisms of OXA-1 and OXA-24 beta-lactamases are determined by the stability of active site carboxylated lysine
J. Biol. Chem.
289
6152-6164
2014
Acinetobacter baumannii (J9XTR7), Escherichia coli (P13661)
Khan, A.; Faheem, M.; Danishuddin, M.; Khan, A.U.
Evaluation of inhibitory action of novel non beta-lactam inhibitor against Klebsiella pneumoniae carbapenemase (KPC-2)
PLoS ONE
9
e108246
2014
Klebsiella pneumoniae (G3GCC6), Klebsiella pneumoniae, Klebsiella pneumoniae NP6 (G3GCC6)
Cha, S.S.; An, Y.J.
Crystal structure of EstSRT1, a family VIII carboxylesterase displaying hydrolytic activity toward oxyimino cephalosporins
Biochem. Biophys. Res. Commun.
478
818-824
2016
uncultured bacterium, uncultured bacterium (A0A0G2RKR9)
Kusada, H.; Tamaki, H.; Kamagata, Y.; Hanada, S.; Kimura, N.
A novel quorum-quenching N-acylhomoserine lactone acylase from Acidovorax sp. strain MR-S7 mediates antibiotic resistance
Appl. Environ. Microbiol.
83
e00080-17
2017
Acidovorax sp. MR-S7 (AB702957)
Rezai, M.S.; Salehifar, E.; Rafiei, A.; Langaee, T.; Rafati, M.; Shafahi, K.; Eslami, G.
Characterization of multidrug resistant extended-spectrum beta-lactamase-producing Escherichia coli among uropathogens of pediatrics in north of Iran
BioMed Res. Int.
2015
309478
2015
Escherichia coli
White, D.S.; Choy, C.J.; Moural, T.W.; Martin, S.E.; Wang, J.; Gargaro, S.; Kang, C.; Berkman, C.E.
Bis(benzoyl) phosphate inactivators of beta-lactamase C from Mtb
Bioorg. Med. Chem. Lett.
29
2116-2118
2019
Mycobacterium tuberculosis (P9WKD3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WKD3), Mycobacterium tuberculosis ATCC 25618 (P9WKD3)
Koga, V.L.; Maluta, R.P.; da Silveira, W.D.; Ribeiro, R.A.; Hungria, M.; Vespero, E.C.; Nakazato, G.; Kobayashi, R.K.T.
Characterization of CMY-2-type beta-lactamase-producing Escherichia coli isolated from chicken carcasses and human infection in a city of South Brazil
BMC Microbiol.
19
174
2019
Escherichia coli (Q53TY8), Escherichia coli
Kumar, G.; Biswal, S.; Nathan, S.; Ghosh, A.S.
Glutamate residues at positions 162 and 164 influence the beta-lactamase activity of SHV-14 obtained from Klebsiella pneumoniae
FEMS Microbiol. Lett.
365
fnx259
2018
Klebsiella pneumoniae (Q9F918), Klebsiella pneumoniae, Klebsiella pneumoniae MTCC 3384 (Q9F918)
Kumar, G.; Issa, B.; Biswal, S.; Jain, D.; Bhattacharjee, A.; Ghosh, A.S.
Glutamic acid at position 152 and serine at position 191 are the key residues required for the metallo-beta-lactamase activity of NDM-7
Int. J. Antimicrob. Agents
55
105824
2019
Klebsiella pneumoniae (A0A173MZL7), Klebsiella pneumoniae NDM-7 (A0A173MZL7)
Gangadharappa, B.S.; Sharath, R.; Revanasiddappa, P.D.; Chandramohan, V.; Balasubramaniam, M.; Vardhineni, T.P.
Structural insights of metallo-beta-lactamase revealed an effective way of inhibition of enzyme by natural inhibitors
J. Biomol. Struct. Dyn.
38
3757-3771
2019
Serratia marcescens (P52699)
Avci, F.G.; Altinisik, F.E.; Vardar Ulu, D.; Ozkirimli Olmez, E.; Sariyar Akbulut, B.
An evolutionarily conserved allosteric site modulates beta-lactamase activity
J. Enzyme Inhib. Med. Chem.
31
33-40
2016
Escherichia coli (Q6SJ61)
Li, S.; Zhu, Z.C.; Wang, L.; Zhou, Y.F.; Tang, Y.J.; Miao, Z.M.
Prevalence and characterization of extended-spectrum beta-lactamase-producing Enterobacteriaceae in spring waters
Lett. Appl. Microbiol.
61
544-548
2015
Klebsiella pneumoniae (D2D9A0), Klebsiella pneumoniae (Q2PUH3), Klebsiella pneumoniae, Escherichia coli (Q0GA57), Escherichia coli (Q840M4), Escherichia coli (Q9EXV5), Escherichia coli (Q9L5C7), Escherichia coli
Banerjee, A.; Bardhan, R.; Chowdhury, M.; Joardar, S.N.; Isore, D.P.; Batabyal, K.; Dey, S.; Sar, T.K.; Bandyopadhyay, S.; Dutta, T.K.; Samanta, I.
Characterization of beta-lactamase and biofilm producing Enterobacteriaceae isolated from organized and backyard farm ducks
Lett. Appl. Microbiol.
69
110-115
2019
Escherichia coli, Klebsiella pneumoniae, Salmonella sp.
Wei, D.D.; Wan, L.G.; Yu, Y.; Xu, Q.F.; Deng, Q.; Cao, X.W.; Liu, Y.
Characterization of extended-spectrum beta-lactamase, carbapenemase, and plasmid quinolone determinants in Klebsiella pneumoniae isolates carrying distinct types of 16S rRNA methylase genes, and their association with mobile genetic elements
Microb. Drug Resist.
21
186-193
2015
Klebsiella pneumoniae (C7C422), Klebsiella pneumoniae (Q2PUH3), Klebsiella pneumoniae (Q48434), Klebsiella pneumoniae (Q4LDF1), Klebsiella pneumoniae (Q93LQ9), Klebsiella pneumoniae
Porres-Osante, N.; Saenz, Y.; Somalo, S.; Torres, C.
Characterization of beta-lactamases in faecal Enterobacteriaceae recovered from healthy humans in Spain focusing on AmpC polymorphisms
Microb. Ecol.
70
132-140
2015
Citrobacter freundii (A3RLA9), Citrobacter freundii (H6UZZ2), Citrobacter freundii (H6UZZ8), Citrobacter freundii (I3QHT4), Citrobacter freundii (I3QHT7), Citrobacter freundii (X2EXH4), Citrobacter freundii, Citrobacter braakii (K0GES5), Citrobacter braakii (K0GET7), Citrobacter braakii (K0GG60), Citrobacter braakii, Enterobacter cloacae (K0GEV1), Enterobacter cloacae (K0GEV3), Enterobacter cloacae (K0GG70), Enterobacter cloacae (Q8KP20), Enterobacter cloacae (X2EXI0), Enterobacter cloacae (X2EXI1), Enterobacter cloacae (X2EXI6), Enterobacter cloacae
Lee, D.; Das, S.; Dawson, N.L.; Dobrijevic, D.; Ward, J.; Orengo, C.
Novel computational protocols for functionally classifying and characterising serine beta-lactamases
PLoS Comput. Biol.
12
e1004926
2016
Escherichia coli (P62593), Escherichia coli (Q47066)
Bansal, A.; Kar, D.; Pandey, S.D.; Matcha, A.; Kumar, N.G.; Nathan, S.; Ghosh, A.S.
A tyrosine residue along with a glutamic acid of the omega-like loop governs the beta-lactamase activity of MSMEG_4455 in Mycobacterium smegmatis
Protein J.
36
220-227
2017
Mycolicibacterium smegmatis (A0R0P0), Mycolicibacterium smegmatis, Mycolicibacterium smegmatis ATCC 700084 (A0R0P0), Mycolicibacterium smegmatis mc(2)155 (A0R0P0)
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