Reference on EC 3.5.1.103 - N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hayward, D.; Wiid, I.; van Helden, P.
Differential expression of mycothiol pathway genes: are they affected by antituberculosis drugs?
IUBMB Life
56
131-138
2004
Mycobacterium tuberculosis (P9WJN3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WJN3)
McCarthy, A.A.; Knijff, R.; Peterson, N.A.; Baker, E.N.
Crystallization and preliminary X-ray analysis of N-acetyl-1-D-myo-inosityl-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis
Acta Crystallogr. Sect. D
59
2316-2318
2003
Mycobacterium tuberculosis (P9WJN3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WJN3)
Nicholas, G.M.; Eckman, L.L.; Kovac, P.; Otero-Quintero, S.; Bewley, C.A.
Synthesis of 1-D- and 1-L-myo-inosityl 2-N-acetamido-2-deoxy-alpha-D-glucopyranoside establishes substrate specificity of the Mycobacterium tuberculosis enzyme AcGI deacetylase
Bioorg. Med. Chem.
11
2641-2647
2003
Mycobacterium tuberculosis (P9WJN3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WJN3)
Gammon, D.W.; Steenkamp, D.J.; Mavumengwana, V.; Marakalala, M.J.; Mudzunga, T.T.; Hunter, R.; Munyololo, M.
Conjugates of plumbagin and phenyl-2-amino-1-thioglucoside inhibit MshB, a deacetylase involved in the biosynthesis of mycothiol
Bioorg. Med. Chem.
18
2501-2514
2010
Mycobacterium tuberculosis
Newton, G.L.; Av-Gay, Y.; Fahey, R.C.
N-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) is a key enzyme in mycothiol biosynthesis
J. Bacteriol.
182
6958-6963
2000
Mycobacterium tuberculosis (P9WJN3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WJN3)
Maynes, J.T.; Garen, C.; Cherney, M.M.; Newton, G.; Arad, D.; Av-Gay, Y.; Fahey, R.C.; James, M.N.
The crystal structure of 1-D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis reveals a zinc hydrolase with a lactate dehydrogenase fold
J. Biol. Chem.
278
47166-47170
2003
Mycobacterium tuberculosis (P9WJN3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WJN3)
McCarthy, A.A.; Peterson, N.A.; Knijff, R.; Baker, E.N.
Crystallization and preliminary X-ray analysis of N-acetyl-1-D-myo-inosityl-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis
J. Mol. Biol.
335
1131-1141
2004
Mycobacterium tuberculosis (P9WJN3), Mycobacterium tuberculosis H37Rv (P9WJN3)
Rawat, M.; Kovacevic, S.; Billman-Jacobe, H.; Av-Gay, Y.
Inactivation of mshB, a key gene in the mycothiol biosynthesis pathway in Mycobacterium smegmatis
Microbiology
149
1341-1349
2003
Mycolicibacterium smegmatis, Mycolicibacterium smegmatis (A0R2I7), Mycolicibacterium smegmatis mc(2)155 / ATCC 700084 (A0R2I7)
Newton, G.L.; Ko, M.; Ta, P.; Av-Gay, Y.; Fahey, R.C.
Purification and characterization of Mycobacterium tuberculosis 1D-myo-inosityl-2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase, MshB, a mycothiol biosynthetic enzyme
Protein Expr. Purif.
47
542-550
2006
Mycobacterium tuberculosis (P9WJN3), Mycobacterium tuberculosis, Mycobacterium tuberculosis H37Rv (P9WJN3)
Huang, X.; Hernick, M.
A fluorescence-based assay for measuring N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase activity
Anal. Biochem.
414
278-281
2011
Mycolicibacterium smegmatis
Huang, X.; Kocabas, E.; Hernick, M.
The activity and cofactor preferences of N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) change depending on environmental conditions
J. Biol. Chem.
286
20275-20282
2011
Mycolicibacterium smegmatis
Huang, X.; Hernick, M.
Examination of mechanism of N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) reveals unexpected role for dynamic tyrosine
J. Biol. Chem.
287
10424-10434
2012
Mycolicibacterium smegmatis
Broadley, S.G.; Gumbart, J.C.; Weber, B.W.; Marakalala, M.J.; Steenkamp, D.J.; Sewell, B.T.
A new crystal form of MshB from Mycobacterium tuberculosis with glycerol and acetate in the active site suggests the catalytic mechanism
Acta Crystallogr. Sect. D
68
1450-1459
2012
Mycobacterium tuberculosis (P9WJN3)
Huang, X.; Hernick, M.
Automated docking studies provide insights into molecular determinants of ligand recognition by N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB)
Biopolymers
101
406-417
2014
Mycobacterium tuberculosis (P9WJN3)
Lamprecht, D.A.; Muneri, N.O.; Eastwood, H.; Naidoo, K.J.; Strauss, E.; Jardine, A.
An enzyme-initiated Smiles rearrangement enables the development of an assay of MshB, the GlcNAc-Ins deacetylase of mycothiol biosynthesis
Org. Biomol. Chem.
10
5278-5288
2012
Mycobacterium tuberculosis (P9WJN3), Mycobacterium tuberculosis
Huang, X.; Hernick, M.
Molecular determinants of N-acetylglucosamine recognition and turnover by N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB)
Biochemistry
54
3784-3790
2015
Mycobacterium tuberculosis (P9WJN3), Mycobacterium tuberculosis ATCC 25618 (P9WJN3)
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