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Information on EC 3.5.1.100 - (R)-amidase

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EC Tree
     3 Hydrolases
         3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
             3.5.1 In linear amides
                3.5.1.100 (R)-amidase
IUBMB Comments
In addition (R)-piperidine-3-carboxamide is hydrolysed to (R)-piperidine-3-carboxylic acid and NH3, and (R)-N-tert-butylpiperazine-2-carboxamide is hydrolysed to (R)-piperazine-2-carboxylic acid and tert-butylamine with lower activity. The enzyme does not act on the other amide substrates which are hydrolysed by EC 3.5.1.4 (amidase).
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Word Map
The expected taxonomic range for this enzyme is: Bacteria, Archaea
Synonyms
r-amidase, r-stereoselective amidase, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
(R)-piperazine-2-carboxamide + H2O = (R)-piperazine-2-carboxylate + NH3
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beta-alaninamide + H2O = beta-alanine + NH3
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