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Acne Vulgaris
Variants in SELL, MRPS36P2, TP63, DDB2, CACNA1H, ADAM19, GNAI1, CDH13 and GABRG2 interact to confer risk of acne in Chinese population.
Alzheimer Disease
ADAM19 is tightly associated with constitutive Alzheimer's disease APP alpha-secretase in A172 cells.
Alzheimer Disease
ADAM19/adamalysin 19 structure, function, and role as a putative target in tumors and inflammatory diseases.
Astrocytoma
ADAM19/adamalysin 19 structure, function, and role as a putative target in tumors and inflammatory diseases.
Brain Neoplasms
ADAM19/adamalysin 19 structure, function, and role as a putative target in tumors and inflammatory diseases.
Brain Neoplasms
Metalloproteinase disintegrins ADAM8 and ADAM19 are highly regulated in human primary brain tumors and their expression levels and activities are associated with invasiveness.
Breast Neoplasms
The elevated transcription of ADAM19 by the oncohistone H2BE76K contributes to oncogenic properties in breast cancer.
Carcinogenesis
Novel insights on m6A RNA methylation in tumorigenesis: a double-edged sword.
Carcinoma
EMT is associated with an epigenetic signature of ECM remodeling genes.
Carcinoma
The elevated transcription of ADAM19 by the oncohistone H2BE76K contributes to oncogenic properties in breast cancer.
Carcinoma, Non-Small-Cell Lung
MiR-145 changes sensitivity of non-small cell lung cancer to gefitinib through targeting ADAM19.
Choriocarcinoma
Dynamic change of Adamalysin 19 (ADAM19) in human placentas and its effects on cell invasion and adhesion in human trophoblastic cells.
Colonic Neoplasms
Role of microRNA-30c targeting ADAM19 in colorectal cancer.
Colorectal Neoplasms
Role of microRNA-30c targeting ADAM19 in colorectal cancer.
Dermatomyositis
The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies.
Endometrial Neoplasms
[Expression and clinical significance of ADAM19 in endometrial carcinoma]
Glioblastoma
ADAM19/adamalysin 19 structure, function, and role as a putative target in tumors and inflammatory diseases.
Glioblastoma
MiR-145 inhibits the epithelial-to-mesenchymal transition via targeting ADAM19 in human glioblastoma.
Glioma
ADAM19/adamalysin 19 structure, function, and role as a putative target in tumors and inflammatory diseases.
Glioma
Metalloproteinase disintegrins ADAM8 and ADAM19 are highly regulated in human primary brain tumors and their expression levels and activities are associated with invasiveness.
Glomerulosclerosis, Focal Segmental
ADAM19 expression in human nephrogenesis and renal disease: Associations with clinical and structural deterioration.
Heart Septal Defects, Ventricular
Essential role for ADAM19 in cardiovascular morphogenesis.
Hemangiosarcoma
Biallelic Dicer1 loss mediated by aP2-Cre drives angiosarcoma.
Insulin Resistance
ADAM19: A Novel Target for Metabolic Syndrome in Humans and Mice.
Kidney Diseases
Upregulation of ADAM19 in chronic allograft nephropathy.
Lung Neoplasms
Long noncoding RNA NORAD regulates lung cancer cell proliferation, apoptosis, migration, and invasion by the miR-30a-5p/ADAM19 axis.
Lung Neoplasms
MiR-145 changes sensitivity of non-small cell lung cancer to gefitinib through targeting ADAM19.
Lung Neoplasms
MiR-153 inhibits migration and invasion of human non-small-cell lung cancer by targeting ADAM19.
Lymphatic Metastasis
Analysis of the clinical significance of DNA methylation in gastric cancer based on a genome-wide high-resolution array.
Lymphoma
Polymorphisms in integrin genes and lymphoma risk.
Metabolic Syndrome
ADAM19: A Novel Target for Metabolic Syndrome in Humans and Mice.
Myositis
The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies.
Myositis, Inclusion Body
The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies.
Nasopharyngeal Carcinoma
MiR-874-3p suppresses cell proliferation and invasion by targeting ADAM19 in nasopharyngeal carcinoma.
Neoplasm Metastasis
Biallelic Dicer1 loss mediated by aP2-Cre drives angiosarcoma.
Neoplasm Metastasis
MiR-145 changes sensitivity of non-small cell lung cancer to gefitinib through targeting ADAM19.
Neoplasms
Aberrant expression of enzymes regulating m6A mRNA methylation: implication in cancer.
Neoplasms
Aberrant transforming growth factor beta1 signaling and SMAD4 nuclear translocation confer epigenetic repression of ADAM19 in ovarian cancer.
Neoplasms
ADAM19/adamalysin 19 structure, function, and role as a putative target in tumors and inflammatory diseases.
Neoplasms
ADAMs in cancer cell proliferation and progression.
Neoplasms
Catalytic properties of ADAM19.
Neoplasms
Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer.
Neoplasms
Metalloproteinase disintegrins ADAM8 and ADAM19 are highly regulated in human primary brain tumors and their expression levels and activities are associated with invasiveness.
Neoplasms
The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies.
Neoplasms
The elevated transcription of ADAM19 by the oncohistone H2BE76K contributes to oncogenic properties in breast cancer.
Neoplasms
Upregulation of ADAM19 in chronic allograft nephropathy.
Neoplasms
[Expression and clinical significance of ADAM19 in endometrial carcinoma]
Obesity
ADAM19: A Novel Target for Metabolic Syndrome in Humans and Mice.
Ovarian Neoplasms
Aberrant transforming growth factor beta1 signaling and SMAD4 nuclear translocation confer epigenetic repression of ADAM19 in ovarian cancer.
Ovarian Neoplasms
Promoter hypermethylation of FBXO32, a novel TGF-beta/SMAD4 target gene and tumor suppressor, is associated with poor prognosis in human ovarian cancer.
Polymyositis
The cell-specific expression of metalloproteinase-disintegrins (ADAMs) in inflammatory myopathies.
Prostatic Neoplasms
Genetic and cellular studies highlight that A Disintegrin and Metalloproteinase 19 is a protective biomarker in human prostate cancer.
Pulmonary Disease, Chronic Obstructive
Genetic underpinnings of lung function and COPD.
Pulmonary Disease, Chronic Obstructive
Genetic Variants in IL6R and ADAM19 are Associated with COPD Severity in a Mexican Mestizo Population.
Pulmonary Disease, Chronic Obstructive
Genome Wide Association Studies Identify CHRNA5/3 and HTR4 in the Development of Airflow Obstruction.
Pulmonary Disease, Chronic Obstructive
The Association of Genome-Wide Significant Spirometric Loci with COPD Susceptibility.
Retinoblastoma
miR-145 suppressed human retinoblastoma cell proliferation and invasion by targeting ADAM19.
Tetralogy of Fallot
PhenomeNET: a whole-phenome approach to disease gene discovery.
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Zhao, M.; Qiu, W.; Li, Y.; Sang, Q.; Wang, Y.
Dynamic change of Adamalysin 19 (ADAM19) in human placentas and its effects on cell invasion and adhesion in human trophoblastic cells
Sci. China C Life Sci.
52
710-718
2009
Homo sapiens
brenda
Tanabe, C.; Hotoda, N.; Sasagawa, N.; Futai, E.; Komano, H.; Ishiura, S.
ADAM19 autolysis is activated by LPS and promotes non-classical secretion of cysteine-rich protein 2
Biochem. Biophys. Res. Commun.
396
927-932
2010
Homo sapiens
brenda
Yoshikawa, A.; Aizaki, Y.; Kusano, K.; Kishi, F.; Susumu, T.; Iida, S.; Ishiura, S.; Nishimura, S.; Shichiri, M.; Senbonmatsu, T.
The (pro)renin receptor is cleaved by ADAM19 in the Golgi leading to its secretion into extracellular space
Hypertens. Res.
34
599-605
2011
Homo sapiens
brenda
Li, J.; Perfetto, M.; Neuner, R.; Bahudhanapati, H.; Christian, L.; Mathavan, K.; Bridges, L.C.; Alfandari, D.; Wei, S.
Xenopus ADAM19 regulates Wnt signaling and neural crest specification by stabilizing ADAM13
Development
145
dev158154
2018
Xenopus tropicalis (Q27JK5)
brenda
Weerasekera, L.; Rudnicka, C.; Sang, Q.X.; Curran, J.E.; Johnson, M.P.; Moses, E.K.; Goering, H.H.; Blangero, J.; Hricova, J.; Schlaich, M.; Matthews, V.B.
ADAM19 A novel target for metabolic syndrome in humans and mice
Mediators Inflamm.
2017
7281986
2017
Mus musculus (O35674), Mus musculus
brenda