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Reference on EC 3.4.24.35 - gelatinase B

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Netzel-Arnett, S.; Sang, Q.X.; Moore, W.G.I.; Navre, M.; Birkedal-Hansen, H.; van Wart, H.E.
Comparative sequence specificities of human 72- and 92-kDa gelatinases (type IV collagenases) and PUMP (matrilysin)
Biochemistry
32
6427-6432
1993
Homo sapiens
Manually annotated by BRENDA team
Nguyen, Q.; Murphy, G.; Hughes, C.E.; Mort, J.S.; Roughley, P.J.
Matrix metalloproteinases cleave at two distinct sites on human cartilage link protein
Biochem. J.
295
595-598
1993
Homo sapiens
Manually annotated by BRENDA team
Ochieng, J.; Fridman, R.; Nangia-Makker, P.; Kleiner, D.E.; Liotta, L.A.; Stetler-Stevenson, W.G.; Raz, A.
Galectin-3 is a novel substrate for human matrix metalloproteinases-2 and -9
Biochemistry
33
14109-14114
1994
Homo sapiens
Manually annotated by BRENDA team
Allan, J.A.; Docherty, A.J.P.; Barker, P.J.; Huskisson, N.S.; Reynolds, J.J.; Murphy, G.
Binding of gelatinases A and B to type-I collagen and other matrix components
Biochem. J.
309
299-306
1995
Homo sapiens
Manually annotated by BRENDA team
Imai, K.; Shikata, H.; Okada, Y.
Degradation of vitronectin by matrix metalloproteinases-1, -2, -3, -7 and -9
FEBS Lett.
369
249-251
1995
Homo sapiens
Manually annotated by BRENDA team
Wilhelm, S.M.; Collier, I.E.; Marmer, B.L.; Eisen, A.Z.; Grant, G.A.; Goldberg, G.I.
SV40-transformed human lung fibroblasts secrete a 92-kDa type IV collagenase which is identical to that secreted by normal human macrophages [published erratum appears in J Biol Chem 1990 Dec 25;265(36):22570]
J. Biol. Chem.
264
17213-17221
1989
Homo sapiens
Manually annotated by BRENDA team
O'Connelll, J.P.; Willenbrock, F.; Docherty, A.J.P.; Eaton, D.; Murphy, G.
Analysis of the role of the COOH-terminal domain in the activation, proteolytic activity, and tissue inhibitor of metalloproteinase interactions of gelatinase B
J. Biol. Chem.
269
14967-14973
1994
Homo sapiens
Manually annotated by BRENDA team
McGeehan, G.M.; Bickett, D.M.; Green, M.; Kassel, D.; Wiseman, J.S.; Berman, J.
Characterization of the peptide substrate specificities of interstitial collagenase and 92-kDa gelatinase. Implications for substrate optimization
J. Biol. Chem.
269
32814-32820
1994
Homo sapiens
Manually annotated by BRENDA team
Sires, U.I.; Dublet, B.; Aubert-Foucher, E.; van der Rest, M.; Welgus, H.G.
Degradation of the COL1 domain of type XIV collagen by 92-kDa gelatinase
J. Biol. Chem.
270
1062-1067
1995
Homo sapiens
Manually annotated by BRENDA team
Niyibizi, C.; Chan, R.; Wu, J.J.; Eyre, D.
A 92 kDa gelatinase (MMP-9) cleavage site in native type V collagen
Biochem. Biophys. Res. Commun.
202
328-333
1994
Oryctolagus cuniculus
Manually annotated by BRENDA team
Morel, F.; Berthier, S.; Guillot, M.; Zaoui, P.; Massoubre, C.; Didier, F.; Vignais, P.V.
Human neutrophil gelatinase is a collagenase type IV
Biochem. Biophys. Res. Commun.
191
269-274
1993
Homo sapiens
Manually annotated by BRENDA team
Pourmotabbed, T.; Aelion, J.A.; Tyrrell, D.; Hasty, K.A.; Bu, C.H.; Mainardi, C.L.
Role of the conserved histidine and aspartic acid residues in activity and stabilization of human gelatinase B: an example of matrix metalloproteinases
J. Protein Chem.
14
527-535
1995
Homo sapiens
Manually annotated by BRENDA team
Desrivieres, S.; Lu, H.; Peyri, N.; Soria, C.; Legrand, Y.; Menashi, S.
Activation of the 92 kDa type IV collagenase by tissue kallikrein
J. Cell. Physiol.
157
587-593
1993
Sus scrofa
Manually annotated by BRENDA team
Ochieng, J.; Warfield, P.; Green, B.
Interactions of gelatinases with soluble and immobilized fetuin and asialofetuin
Arch. Biochem. Biophys.
322
250-255
1995
Homo sapiens
Manually annotated by BRENDA team
Makowski, G.S.; Ramsby, M.L.
Binding of matrix metalloproteinase 9 to fibrin is mediated by amorphous calcium-phosphate
Inflammation
22
599-617
1998
Homo sapiens
Manually annotated by BRENDA team
Olson, M.W.; Bernardo, M.M.; Pietila, M.; Gervasi, D.C.; Toth, M.; Kotra, L.P.; Massova, I.; Mobashery, S.; Fridman, R.
Characterization of the monomeric and dimeric forms of latent and active matrix metalloproteinase-9. Differential rates for activation by stromelysin 1
J. Biol. Chem.
275
2661-2668
2000
Homo sapiens (P45452)
Manually annotated by BRENDA team
Kleifeld, O.; Van den Steen, P.E.; Frenkel, A.; Cheng, F.; Jiang, H.L.; Opdenakker, G.; Sagi, I.
Structural characterization of the catalytic active site in the latent and active natural gelatinase B from human neutrophils
J. Biol. Chem.
275
34335-34343
2000
Homo sapiens
Manually annotated by BRENDA team
Kridel, S.J.; Chen, E.; Kotra, L.P.; Howard, E.W.; Mobashery, S.; Smith, J.W.
Substrate hydrolysis by matrix metalloproteinase-9
J. Biol. Chem.
276
20572-20578
2001
Mus musculus
Manually annotated by BRENDA team
Chen, E.I.; Li, W.; Godzik, A.; Howard, E.W.; Smith, J.W.
A residue in the S2 subsite controls substrate selectivity of matrix metalloproteinase-2 and matrix metalloproteinase-9
J. Biol. Chem.
278
17158-17163
2003
Homo sapiens
Manually annotated by BRENDA team
George, H.J.; Marchand, P.; Murphy, K.; Wiswall, B.H.; Dowling, R.; giannaras, J.; Hollis, G.F.; Trzaskos, J.M.; Copeland, R.A.
Recombinant human 92-kDa type IV collagenase/gelatinase from baculovirus-infected insect cells: expression, purification, and characterization
Protein Expr. Purif.
10
154-161
1997
Homo sapiens
Manually annotated by BRENDA team
Xu, X.; Chen, Z.; Wang, Y.; Yamada, Y.; Steffensen, B.
Functional basis for the overlap in ligand interactions and substrate specificities of matrix metalloproteinases-9 and -2
Biochem. J.
392
127-134
2005
Homo sapiens
Manually annotated by BRENDA team
Hu, J.; Van den Steen, P.E.; Houde, M.; Ilenchuk, T.T.; Opdenakker, G.
Inhibitors of gelatinase B/matrix metalloproteinase-9 activity. Comparison of a peptidomimetic and polyhistidine with single-chain derivatives of a neutralizing monoclonal antibody
Biochem. Pharmacol.
67
1001-1009
2004
Homo sapiens
Manually annotated by BRENDA team
Van den Steen, P.E.; Proost, P.; Brand, D.D.; Kang, A.H.; Van Damme, J.; Opdenakker, G.
Generation of glycosylated remnant epitopes from human collagen type II by gelatinase B
Biochemistry
43
10809-10816
2004
Homo sapiens
Manually annotated by BRENDA team
Rossello, A.; Nuti, E.; Orlandini, E.; Carelli, P.; Rapposelli, S.; Macchia, M.; Minutolo, F.; Carbonaro, L.; Albini, A.; Benelli, R.; Cercignani, G.; Murphy, G.; Balsamo, A.
New N-arylsulfonyl-N-alkoxyaminoacetohydroxamic acids as selective inhibitors of gelatinase A (MMP-2)
Bioorg. Med. Chem.
12
2441-2450
2004
Homo sapiens
Manually annotated by BRENDA team
Meyer, E.; Vollmer, J.Y.; Bovey, R.; Stamenkovic, I.
Matrix metalloproteinases 9 and 10 inhibit protein kinase C-potentiated, p53-mediated apoptosis
Cancer Res.
65
4261-4272
2005
Homo sapiens
Manually annotated by BRENDA team
Defawe, O.D.; Kenagy, R.D.; Choi, C.; Wan, S.Y.; Deroanne, C.; Nusgens, B.; Sakalihasan, N.; Colige, A.; Clowes, A.W.
MMP-9 regulates both positively and negatively collagen gel contraction: a nonproteolytic function of MMP-9
Cardiovasc. Res.
66
402-409
2005
Rattus norvegicus
Manually annotated by BRENDA team
Chintala, S.K.; Wang, N.; Diskin, S.; Mattox, C.; Kagemann, L.; Fini, M.E.; Schuman, J.S.
Matrix metalloproteinase gelatinase B (MMP-9) is associated with leaking glaucoma filtering blebs
Exp. Eye Res.
81
429-436
2005
Homo sapiens
Manually annotated by BRENDA team
Descamps, F.J.; Martens, E.; Kangave, D.; Struyf, S.; Geboes, K.; Van Damme, J.; Opdenakker, G.; Abu El-Asrar, A.M.
The activated form of gelatinase B/matrix metalloproteinase-9 is associated with diabetic vitreous hemorrhage
Exp. Eye Res.
83
401-407
2006
Homo sapiens
Manually annotated by BRENDA team
Abu El-Asrar, A.M.; Struyf, S.; Van den Broeck, C.; Van Damme, J.; Opdenakker, G.; Geboes, K.; Kestelyn, P.
Expression of chemokines and gelatinase B in sympathetic ophthalmia
Eye
21
649-657
2006
Homo sapiens
Manually annotated by BRENDA team
Descamps, F.J.; Martens, E.; Proost, P.; Starckx, S.; Van den Steen, P.E.; Van Damme, J.; Opdenakker, G.
Gelatinase B/matrix metalloproteinase-9 provokes cataract by cleaving lens betaB1 crystallin
FASEB J.
19
29-35
2005
Homo sapiens
Manually annotated by BRENDA team
Di Carlo, A.; Terracciano, D.; Mariano, A.; Macchia, V.
Matrix metalloproteinase-2 and matrix metalloproteinase-9 type IV collagenases in serum of patients with pleural effusions
Int. J. Oncol.
26
1363-1368
2005
Homo sapiens
Manually annotated by BRENDA team
Gonzalez-Cuevas, J.; Bueno-Topete, M.; Armendariz-Borunda, J.
Urokinase plasminogen activator stimulates function of active forms of stromelysin and gelatinases (MMP-2 and MMP-9) in cirrhotic tissue
J. Gastroenterol. Hepatol.
21
1544-1554
2006
Rattus norvegicus
Manually annotated by BRENDA team
Di Girolamo, N.; Indoh, I.; Jackson, N.; Wakefield, D.; McNeil, H.P.; Yan, W.; Geczy, C.; Arm, J.P.; Tedla, N.
Human mast cell-derived gelatinase B (matrix metalloproteinase-9) is regulated by inflammatory cytokines: role in cell migration
J. Immunol.
177
2638-2650
2006
Homo sapiens
Manually annotated by BRENDA team
Shimanovich, I.; Mihai, S.; Oostingh, G.J.; Ilenchuk, T.T.; Broecker, E.B.; Opdenakker, G.; Zillikens, D.; Sitaru, C.
Granulocyte-derived elastase and gelatinase B are required for dermal-epidermal separation induced by autoantibodies from patients with epidermolysis bullosa acquisita and bullous pemphigoid
J. Pathol.
204
519-527
2004
Homo sapiens
Manually annotated by BRENDA team
Leveque, T.; Le Pavec, G.; Boutet, A.; Tardieu, M.; Dormont, D.; Gras, G.
Differential regulation of gelatinase A and B and TIMP-1 and -2 by TNFalpha and HIV virions in astrocytes
Microbes Infect.
6
157-163
2004
Homo sapiens
Manually annotated by BRENDA team
Lindberg, R.L.; Sorsa, T.; Tervahartiala, T.; Hoffmann, F.; Mellanen, L.; Kappos, L.; Schaad, U.B.; Leib, S.L.; Leppert, D.
Gelatinase B [matrix metalloproteinase (MMP)-9] and collagenases (MMP-8/-13) are upregulated in cerebrospinal fluid during aseptic and bacterial meningitis in children
Neuropathol. Appl. Neurobiol.
32
304-317
2006
Homo sapiens
Manually annotated by BRENDA team
Di Carlo, A.; Terracciano, D.; Mariano, A.; Macchia, V.
Urinary gelatinase activities (matrix metalloproteinases 2 and 9) in human bladder tumors
Oncol. Rep.
15
1321-1326
2006
Homo sapiens
Manually annotated by BRENDA team
Zhang, L.; Shi, J.; Feng, J.; Klocker, H.; Lee, C.; Zhang, J.
Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer
Prostate Cancer Prostatic. Dis.
7
327-332
2004
Homo sapiens
Manually annotated by BRENDA team
Adair, J.C.; Charlie, J.; Dencoff, J.E.; Kaye, J.A.; Quinn, J.F.; Camicioli, R.M.; Stetler-Stevenson, W.G.; Rosenberg, G.A.
Measurement of gelatinase B (MMP-9) in the cerebrospinal fluid of patients with vascular dementia and Alzheimer disease
Stroke
35
e159-e162
2004
Homo sapiens
Manually annotated by BRENDA team
Unsal, D.; Akyurek, N.; Uner, A.; Erpolat, O.P.; Han, U.; Akmansu, M.; Mentes, B.B.; Dursun, A.
Gelatinase B expression as a prognostic factor in patients with stage II/III rectal carcinoma treated by postoperative adjuvant therapy
Am. J. Clin. Oncol.
31
55-63
2008
Homo sapiens
Manually annotated by BRENDA team
Kim, J.H.; Suk, M.H.; Yoon, D.W.; Lee, S.H.; Hur, G.Y.; Jung, K.H.; Jeong, H.C.; Lee, S.Y.; Lee, S.Y.; Suh, I.B.; Shin, C.; Shim, J.J.; In, K.H.; Yoo, S.H.; Kang, K.H.
Inhibition of matrix metalloproteinase-9 prevents neutrophilic inflammation in ventilator-induced lung injury
Am. J. Physiol. Lung Cell Mol. Physiol.
291
L580-L587
2006
Rattus norvegicus
Manually annotated by BRENDA team
Deshmukh, H.S.; Shaver, C.; Case, L.M.; Dietsch, M.; Wesselkamper, S.C.; Hardie, W.D.; Korfhagen, T.R.; Corradi, M.; Nadel, J.A.; Borchers, M.T.; Leikauf, G.D.
Acrolein-activated matrix metalloproteinase 9 contributes to persistent mucin production
Am. J. Respir. Cell Mol. Biol.
38
446-454
2008
Mus musculus
Manually annotated by BRENDA team
Lau, A.C.; Duong, T.T.; Ito, S.; Yeung, R.S.
Matrix metalloproteinase 9 activity leads to elastin breakdown in an animal model of Kawasaki disease
Arthritis Rheum.
58
854-863
2008
Mus musculus
Manually annotated by BRENDA team
Barbosa, F.; Gerlach, R.F.; Tanus-Santos, J.E.
Matrix metalloproteinase-9 activity in plasma correlates with plasma and whole blood lead concentrations
Basic Clin. Pharmacol. Toxicol.
98
559-564
2006
Homo sapiens
Manually annotated by BRENDA team
Geurts, N.; Martens, E.; Van Aelst, I.; Proost, P.; Opdenakker, G.; Van den Steen, P.E.
Beta-hematin interaction with the hemopexin domain of gelatinase B/MMP-9 provokes autocatalytic processing of the propeptide, thereby priming activation by MMP-3
Biochemistry
47
2689-2699
2008
Homo sapiens
Manually annotated by BRENDA team
Martens, E.; Leyssen, A.; Van Aelst, I.; Fiten, P.; Piccard, H.; Hu, J.; Descamps, F.J.; Van den Steen, P.E.; Proost, P.; Van Damme, J.; Liuzzi, G.M.; Riccio, P.; Polverini, E.; Opdenakker, G.
A monoclonal antibody inhibits gelatinase B/MMP-9 by selective binding to part of the catalytic domain and not to the fibronectin or zinc binding domains
Biochim. Biophys. Acta
1770
178-186
2007
Homo sapiens (P14780), Homo sapiens
Manually annotated by BRENDA team
Moroy, G.; Denhez, C.; El Mourabit, H.; Toribio, A.; Dassonville, A.; Decarme, M.; Renault, J.H.; Mirand, C.; Bellon, G.; Sapi, J.; Alix, A.J.; Hornebeck, W.; Bourguet, E.
Simultaneous presence of unsaturation and long alkyl chain at P1 of Ilomastat confers selectivity for gelatinase A (MMP-2) over gelatinase B (MMP-9) inhibition as shown by molecular modelling studies
Bioorg. Med. Chem.
15
4753-4766
2007
Homo sapiens
Manually annotated by BRENDA team
Mendis, E.; Kim, M.M.; Rajapakse, N.; Kim, S.K.
Carboxy derivatized glucosamine is a potent inhibitor of matrix metalloproteinase-9 in HT1080 cells
Bioorg. Med. Chem. Lett.
16
3105-3110
2006
Homo sapiens
Manually annotated by BRENDA team
Soeder, S.; Roach, H.I.; Oehler, S.; Bau, B.; Haag, J.; Aigner, T.
MMP-9/gelatinase B is a gene product of human adult articular chondrocytes and increased in osteoarthritic cartilage
Clin. Exp. Rheumatol.
24
302-304
2006
Homo sapiens
Manually annotated by BRENDA team
Jeyabalan, A.; Novak, J.; Doty, K.D.; Matthews, J.; Fisher, M.C.; Kerchner, L.J.; Conrad, K.P.
Vascular matrix metalloproteinase-9 mediates the inhibition of myogenic reactivity in small arteries isolated from rats after short-term administration of relaxin
Endocrinology
148
189-197
2007
Rattus norvegicus
Manually annotated by BRENDA team
Zhao, J.X.; Yang, L.P.; Wang, Y.F.; Qin, L.P.; Liu, D.Q.; Bai, C.X.; Nan, X.; Shi, S.S.; Pei, X.J.
Gelatinolytic activity of matrix metalloproteinase-2 and matrix metalloproteinase-9 in rat brain after implantation of 9L rat glioma cells
Eur. J. Neurol.
14
510-516
2007
Rattus norvegicus
Manually annotated by BRENDA team
Lee, Y.M.; Lee, J.J.; Shen, M.Y.; Hsiao, G.; Sheu, J.R.
Inhibitory mechanisms of activated matrix metalloproteinase-9 on platelet activation
Eur. J. Pharmacol.
537
52-58
2006
Homo sapiens
Manually annotated by BRENDA team
Roderfeld, M.; Weiskirchen, R.; Wagner, S.; Berres, M.L.; Henkel, C.; Groetzinger, J.; Gressner, A.M.; Matern, S.; Roeb, E.
Inhibition of hepatic fibrogenesis by matrix metalloproteinase-9 mutants in mice
FASEB J.
20
444-454
2006
Mus musculus, Mus musculus BALB/c
Manually annotated by BRENDA team
Bigg, H.F.; Rowan, A.D.; Barker, M.D.; Cawston, T.E.
Activity of matrix metalloproteinase-9 against native collagen types I and III
FEBS J.
274
1246-1255
2007
Homo sapiens
Manually annotated by BRENDA team
Bergin, P.J.; Raghavan, S.; Svensson, H.; Starckx, S.; Van Aelst, I.; Gjertsson, I.; Opdenakker, G.; Quiding-Jaerbrink, M.
Gastric gelatinase B/matrix metalloproteinase-9 is rapidly increased in Helicobacter felis-induced gastritis
FEMS Immunol. Med. Microbiol.
52
88-98
2008
Mus musculus, Mus musculus C57BL/6
Manually annotated by BRENDA team
Abdallah, M.A.; Kang, S.; Nakajima, S.T.; Gercel-Taylor, C.
Matrix metalloproteinase-9 activity in the plasma of patients after surgical resection of endometriomas
Fertil. Steril.
85
1847-1848
2006
Homo sapiens
Manually annotated by BRENDA team
Peschos, D.; Damala, C.; Stefanou, D.; Tsanou, E.; Assimakopoulos, D.; Vougiouklakis, T.; Charalabopoulos, K.; Agnantis, N.J.
Expression of matrix metalloproteinase-9 (gelatinase B) in benign, premalignant and malignant laryngeal lesions
Histol. Histopathol.
21
603-608
2006
Homo sapiens
Manually annotated by BRENDA team
Cho, Y.B.; Lee, W.Y.; Song, S.Y.; Shin, H.J.; Yun, S.H.; Chun, H.K.
Matrix metalloproteinase-9 activity is associated with poor prognosis in T3-T4 node-negative colorectal cancer
Hum. Pathol.
38
1603-1610
2007
Homo sapiens
Manually annotated by BRENDA team
Kolaczkowska, E.; Chadzinska, M.; Scislowska-Czarnecka, A.; Plytycz, B.; Opdenakker, G.; Arnold, B.
Gelatinase B/matrix metalloproteinase-9 contributes to cellular infiltration in a murine model of zymosan peritonitis
Immunobiology
211
137-148
2006
Mus musculus, Mus musculus BALB/c
Manually annotated by BRENDA team
Kolaczkowska, E.; Arnold, B.; Opdenakker, G.
Gelatinase B/MMP-9 as an inflammatory marker enzyme in mouse zymosan peritonitis: comparison of phase-specific and cell-specific production by mast cells, macrophages and neutrophils
Immunobiology
213
109-124
2008
Mus musculus, Mus musculus C57BL/6
Manually annotated by BRENDA team
Ko, H.M.; Kang, J.H.; Jung, B.; Kim, H.A.; Park, S.J.; Kim, K.J.; Kang, Y.R.; Lee, H.K.; Im, S.Y.
Critical role for matrix metalloproteinase-9 in platelet-activating factor-induced experimental tumor metastasis
Int. J. Cancer
120
1277-1283
2007
Mus musculus
Manually annotated by BRENDA team
Strek, M.; Gorlach, S.; Podsedek, A.; Sosnowska, D.; Koziolkiewicz, M.; Hrabec, Z.; Hrabec, E.
Procyanidin oligomers from Japanese quince (Chaenomeles japonica) fruit inhibit activity of MMP-2 and MMP-9 metalloproteinases
J. Agric. Food Chem.
55
6447-6452
2007
Homo sapiens
Manually annotated by BRENDA team
Vempati, P.; Karagiannis, E.D.; Popel, A.S.
A biochemical model of matrix metalloproteinase 9 activation and inhibition
J. Biol. Chem.
282
37585-37596
2007
Homo sapiens
Manually annotated by BRENDA team
Mazzoni, A.; Mannello, F.; Tay, F.R.; Tonti, G.A.; Papa, S.; Mazzotti, G.; Di Lenarda, R.; Pashley, D.H.; Breschi, L.
Zymographic analysis and characterization of MMP-2 and -9 forms in human sound dentin
J. Dent. Res.
86
436-440
2007
Homo sapiens
Manually annotated by BRENDA team
Malik, M.; Bakshi, C.S.; McCabe, K.; Catlett, S.V.; Shah, A.; Singh, R.; Jackson, P.L.; Gaggar, A.; Metzger, D.W.; Melendez, J.A.; Blalock, J.E.; Sellati, T.J.
Matrix metalloproteinase 9 activity enhances host susceptibility to pulmonary infection with type A and B strains of Francisella tularensis
J. Immunol.
178
1013-1020
2007
Mus musculus, Mus musculus FVB/NJ
Manually annotated by BRENDA team
Ho, T.Y.; Yan, W.; Bagnell, C.A.
Relaxin-induced matrix metalloproteinase-9 expression is associated with activation of the NF-kappaB pathway in human THP-1 cells
J. Leukoc. Biol.
81
1303-1310
2007
Homo sapiens
Manually annotated by BRENDA team
Swarnakar, S.; Mishra, A.; Ganguly, K.; Sharma, A.V.
Matrix metalloproteinase-9 activity and expression is reduced by melatonin during prevention of ethanol-induced gastric ulcer in mice
J. Pineal Res.
43
56-64
2007
Mus musculus, Mus musculus BALB/c
Manually annotated by BRENDA team
Van Ta, Q.; Kim, M.M.; Kim, S.K.
Inhibitory effect of chitooligosaccharides on matrix metalloproteinase-9 in human fibrosarcoma cells (HT1080)
Mar. Biotechnol.
8
593-599
2007
Homo sapiens
Manually annotated by BRENDA team
Thornton, P.; Pinteaux, E.; Allan, S.M.; Rothwell, N.J.
Matrix metalloproteinase-9 and urokinase plasminogen activator mediate interleukin-1-induced neurotoxicity
Mol. Cell. Neurosci.
37
135-142
2008
Rattus norvegicus
Manually annotated by BRENDA team
Garcia-Lopez, G.; Vadillo-Ortega, F.; Merchant-Larios, H.; Maida-Claros, R.; Osorio, M.; Soriano-Becerril, D.; Flores-Herrera, H.; Beltran-Montoya, J.; Garfias-Becerra, Y.; Zaga-Clavellina, V.
Evidence of in vitro differential secretion of 72 and 92 kDa type IV collagenases after selective exposure to lipopolysaccharide in human fetal membranes
Mol. Hum. Reprod.
13
409-418
2007
Homo sapiens
Manually annotated by BRENDA team
Marco, M.; Baz, A.; Fernandez, C.; Gonzalez, G.; Hellman, U.; Salinas, G.; Nieto, A.
A relevant enzyme in granulomatous reaction, active matrix metalloproteinase-9, found in bovine Echinococcus granulosus hydatid cyst wall and fluid
Parasitol. Res.
100
131-139
2006
Bos taurus
Manually annotated by BRENDA team
Ridnour, L.A.; Windhausen, A.N.; Isenberg, J.S.; Yeung, N.; Thomas, D.D.; Vitek, M.P.; Roberts, D.D.; Wink, D.A.
Nitric oxide regulates matrix metalloproteinase-9 activity by guanylyl-cyclase-dependent and -independent pathways
Proc. Natl. Acad. Sci. USA
104
16898-16903
2007
Mus musculus, Mus musculus C57BL/6
Manually annotated by BRENDA team
Rosenblum, G.; Van den Steen, P.E.; Cohen, S.R.; Grossmann, J.G.; Frenkel, J.; Sertchook, R.; Slack, N.; Strange, R.W.; Opdenakker, G.; Sagi, I.
Insights into the structure and domain flexibility of full-length pro-matrix metalloproteinase-9/gelatinase B
Structure
15
1227-1236
2007
Homo sapiens
Manually annotated by BRENDA team
Dragutinovic, V.V.; Radovanovic, N.S.; Izrael-Zivkovic, L.T.; Vrvic, M.M.
Detection of gelatinase B activity in serum of gastric cancer patients
World J. Gastroenterol.
12
105-109
2006
Homo sapiens
Manually annotated by BRENDA team
Bhattacharyya, S.; Tobacman, J.K.
Arylsulfatase B regulates colonic epithelial cell migration by effects on MMP9 expression and RhoA activation
Clin. Exp. Metastasis
26
535-545
2009
Homo sapiens
Manually annotated by BRENDA team
Addabbo, F.; Ratliff, B.; Park, H.C.; Kuo, M.C.; Ungvari, Z.; Csiszar, A.; Ciszar, A.; Krasnikov, B.; Krasnikof, B.; Sodhi, K.; Zhang, F.; Nasjletti, A.; Goligorsky, M.S.
The Krebs cycle and mitochondrial mass are early victims of endothelial dysfunction: proteomic approach
Am. J. Pathol.
174
34-43
2009
Mus musculus
Manually annotated by BRENDA team
Lin, C.K.; Chao, T.K.; Yu, C.P.; Yu, M.H.; Jin, J.S.
The expression of six biomarkers in the four most common ovarian cancers: correlation with clinicopathological parameters
APMIS
117
162-175
2009
Homo sapiens
Manually annotated by BRENDA team
Wagner, S.; Breyholz, H.J.; Hoeltke, C.; Faust, A.; Schober, O.; Schaefers, M.; Kopka, K.
A new 18F-labelled derivative of the MMP inhibitor CGS 27023A for PET: radiosynthesis and initial small-animal PET studies
Appl. Radiat. Isot.
67
606-610
2009
Mus musculus
Manually annotated by BRENDA team
Hlawaty, H.; Jacob, M.P.; Louedec, L.; Letourneur, D.; Brink, C.; Michel, J.B.; Feldman, L.; Baeck, M.
Leukotriene receptor antagonism and the prevention of extracellular matrix degradation during atherosclerosis and in-stent stenosis
Arterioscler. Thromb. Vasc. Biol.
29
518-524
2009
Oryctolagus cuniculus, Homo sapiens
Manually annotated by BRENDA team
Lee, S.R.; Kim, H.Y.; Hong, J.S.; Baek, W.K.; Park, J.W.
PPARgamma agonist pioglitazone reduces matrix metalloproteinase-9 activity and neuronal damage after focal cerebral ischemia
Biochem. Biophys. Res. Commun.
380
17-21
2009
Mus musculus
Manually annotated by BRENDA team
Moore, R.M.; Novak, J.B.; Kumar, D.; Mansour, J.M.; Mercer, B.M.; Moore, J.J.
Alpha-lipoic acid inhibits tumor necrosis factor-induced remodeling and weakening of human fetal membranes
Biol. Reprod.
80
781-787
2009
Homo sapiens
Manually annotated by BRENDA team
Miyanaga, S.; Sakurai, H.; Saiki, I.; Onaka, H.; Igarashi, Y.
Synthesis and evaluation of myxochelin analogues as antimetastatic agents
Bioorg. Med. Chem.
17
2724-2732
2009
Mus musculus
Manually annotated by BRENDA team
Figueira, R.C.; Gomes, L.R.; Neto, J.S.; Silva, F.C.; Silva, I.D.; Sogayar, M.C.
Correlation between MMPs and their inhibitors in breast cancer tumor tissue specimens and in cell lines with different metastatic potential
BMC Cancer
9
20
2009
Homo sapiens (P14780), Homo sapiens
Manually annotated by BRENDA team
Peng, T.L.; Chen, J.; Mao, W.; Song, X.; Chen, M.H.
Aryl hydrocarbon receptor pathway activation enhances gastric cancer cell invasiveness likely through a c-Jun-dependent induction of matrix metalloproteinase-9
BMC Cell Biol.
10
27
2009
Homo sapiens
Manually annotated by BRENDA team
Zhou, L.; Yan, C.; Gieling, R.G.; Kida, Y.; Garner, W.; Li, W.; Han, Y.P.
Tumor necrosis factor-alpha induced expression of matrix metalloproteinase-9 through p21-activated kinase-1
BMC Immunol.
10
15
2009
Homo sapiens
Manually annotated by BRENDA team
Buhler, L.A.; Samara, R.; Guzman, E.; Wilson, C.L.; Krizanac-Bengez, L.; Janigro, D.; Ethell, D.W.
Matrix metalloproteinase-7 facilitates immune access to the CNS in experimental autoimmune encephalomyelitis
BMC Neurosci.
10
17
2009
Mus musculus (P41245)
Manually annotated by BRENDA team
Ding, J.Y.; Kreipke, C.W.; Schafer, P.; Schafer, S.; Speirs, S.L.; Rafols, J.A.
Synapse loss regulated by matrix metalloproteinases in traumatic brain injury is associated with hypoxia inducible factor-1alpha expression
Brain Res.
1268
125-134
2009
Rattus norvegicus (P50282)
Manually annotated by BRENDA team
Chen, B.; Liao, W.Q.; Xu, N.; Xu, H.; Wen, J.Y.; Yu, C.A.; Liu, X.Y.; Li, C.L.; Zhao, S.M.; Campbell, W.
Adiponectin protects against cerebral ischemia-reperfusion injury through anti-inflammatory action
Brain Res.
1273
129-137
2009
Rattus norvegicus
Manually annotated by BRENDA team
Miyake, K.; Shimada, M.; Nishioka, M.; Sugimoto, K.; Batmunkh, E.; Uto, Y.; Nagasawa, H.; Hori, H.
Downregulation of matrix metalloprotease-9 and urokinase plasminogen activator by TX-1877 results in decreased tumor growth and metastasis on xenograft model of rectal cancer
Cancer Chemother. Pharmacol.
64
885-892
2009
Homo sapiens
Manually annotated by BRENDA team
Wu, J.M.; Sheng, H.; Saxena, R.; Skill, N.J.; Bhat-Nakshatri, P.; Yu, M.; Nakshatri, H.; Maluccio, M.A.
NF-kappaB inhibition in human hepatocellular carcinoma and its potential as adjunct to sorafenib based therapy
Cancer Lett.
278
145-155
2009
Homo sapiens
Manually annotated by BRENDA team
Shen, D.; Tang, Q.; Huang, Z.; Chen, Y.; Xiong, R.; Wu, H.; Huang, J.; Feng, S.; Yan, L.; Bian, Z.
The effects of NK4 on viral myocarditis mice
Cardiovasc. Pathol.
18
323-331
2009
Mus musculus
Manually annotated by BRENDA team
Dwivedi, A.; Slater, S.C.; George, S.J.
MMP-9 and -12 cause N-cadherin shedding and thereby beta-catenin signalling and vascular smooth muscle cell proliferation
Cardiovasc. Res.
81
178-186
2009
Mus musculus
Manually annotated by BRENDA team
Bin Hafeez, B.; Adhami, V.M.; Asim, M.; Siddiqui, I.A.; Bhat, K.M.; Zhong, W.; Saleem, M.; Din, M.; Setaluri, V.; Mukhtar, H.
Targeted knockdown of Notch1 inhibits invasion of human prostate cancer cells concomitant with inhibition of matrix metalloproteinase-9 and urokinase plasminogen activator
Clin. Cancer Res.
15
452-459
2009
Homo sapiens
Manually annotated by BRENDA team
Bjarnegard, N.; Arnqvist, H.J.; Lindstroem, T.; Jonasson, L.; Joensson, A.; Laenne, T.
Long-term hyperglycaemia impairs vascular smooth muscle cell function in women with type 1 diabetes mellitus
Diab. Vasc. Dis. Res.
6
25-31
2009
Homo sapiens
Manually annotated by BRENDA team
Reddy, A.B.; Ramana, K.V.; Srivastava, S.; Bhatnagar, A.; Srivastava, S.K.
Aldose reductase regulates high glucose-induced ectodomain shedding of tumor necrosis factor (TNF)-alpha via protein kinase C-delta and TNF-alpha converting enzyme in vascular smooth muscle cells
Endocrinology
150
63-74
2009
Rattus norvegicus
Manually annotated by BRENDA team
Xiao, J.; Shimada, M.; Liu, W.; Hu, D.; Matsumori, A.
Anti-inflammatory effects of eplerenone on viral myocarditis
Eur. J. Heart Fail.
11
349-353
2009
Mus musculus
Manually annotated by BRENDA team
Khademi, M.; Bornsen, L.; Rafatnia, F.; Andersson, M.; Brundin, L.; Piehl, F.; Sellebjerg, F.; Olsson, T.
The effects of natalizumab on inflammatory mediators in multiple sclerosis: prospects for treatment-sensitive biomarkers
Eur. J. Neurol.
16
528-536
2009
Homo sapiens
Manually annotated by BRENDA team
Choi, S.J.; Jung, K.L.; Oh, S.Y.; Kim, J.H.; Roh, C.R.
Cervicovaginal matrix metalloproteinase-9 and cervical ripening in human term parturition
Eur. J. Obstet. Gynecol. Reprod. Biol.
142
43-47
2009
Homo sapiens
Manually annotated by BRENDA team
Jin, G.; Tsuji, K.; Xing, C.; Yang, Y.G.; Wang, X.; Lo, E.H.
CD47 gene knockout protects against transient focal cerebral ischemia in mice
Exp. Neurol.
217
165-170
2009
Mus musculus
Manually annotated by BRENDA team
Assi, K.; Mills, J.; Owen, D.; Ong, C.; St Arnaud, R.; Dedhar, S.; Salh, B.
Integrin-linked kinase regulates cell proliferation and tumour growth in murine colitis-associated carcinogenesis
Gut
57
931-940
2008
Mus musculus
Manually annotated by BRENDA team
Chen, Y.; Zhang, W.; Geng, N.; Tian, K.; Jack Windsor, L.
MMPs, TIMP-2, and TGF-beta1 in the cancerization of oral lichen planus
Head Neck
30
1237-1245
2008
Homo sapiens
Manually annotated by BRENDA team
Meijer, M.J.; Mieremet-Ooms, M.A.; Sier, C.F.; van Hogezand, R.A.; Lamers, C.B.; Hommes, D.W.; Verspaget, H.W.
Matrix metalloproteinases and their tissue inhibitors as prognostic indicators for diagnostic and surgical recurrence in Crohns disease
Inflamm. Bowel Dis.
15
84-92
2009
Homo sapiens
Manually annotated by BRENDA team
Pareja-Santos, A.; Saraiva, T.C.; Costa, E.P.; Santos, M.F.; Zorn, T.T.; Souza, V.M.; Lopes-Ferreira, M.; Lima, C.
Delayed local inflammatory response induced by Thalassophryne nattereri venom is related to extracellular matrix degradation
Int. J. Exp. Pathol.
90
34-43
2009
Mus musculus
Manually annotated by BRENDA team
Saussez, S.; Cludts, S.; Capouillez, A.; Mortuaire, G.; Smetana, K.; Kaltner, H.; Andre, S.; Leroy, X.; Gabius, H.J.; Decaestecker, C.
Identification of matrix metalloproteinase-9 as an independent prognostic marker in laryngeal and hypopharyngeal cancer with opposite correlations to adhesion/growth-regulatory galectins-1 and -7
Int. J. Oncol.
34
433-439
2009
Homo sapiens
Manually annotated by BRENDA team
Cao, J.; Tang, M.; Li, W.L.; Xie, J.; Du, H.; Tang, W.B.; Wang, H.; Chen, X.W.; Xiao, H.; Li, Y.
Upregulation of activator protein-4 in human colorectal cancer with metastasis
Int. J. Surg. Pathol.
17
16-21
2009
Homo sapiens
Manually annotated by BRENDA team
Lawrence, B.J.; Maase, E.L.; Lin, H.K.; Madihally, S.V.
Multilayer composite scaffolds with mechanical properties similar to small intestinal submucosa
J. Biomed. Mater. Res. A
88
634-643
2009
Homo sapiens
Manually annotated by BRENDA team
Alapure, B.V.; Praveen, M.R.; Gajjar, D.; Vasavada, A.R.; Rajkumar, S.; Johar, K.
Matrix metalloproteinase-9 activity in human lens epithelial cells of cortical, posterior subcapsular, and nuclear cataracts
J. Cataract. Refract. Surg.
34
2063-2067
2008
Homo sapiens
Manually annotated by BRENDA team
Adiseshaiah, P.; Vaz, M.; Machireddy, N.; Kalvakolanu, D.V.; Reddy, S.P.
A Fra-1-dependent, matrix metalloproteinase driven EGFR activation promotes human lung epithelial cell motility and invasion
J. Cell. Physiol.
216
405-412
2008
Mus musculus
Manually annotated by BRENDA team
Montagnana, M.; Lippi, G.; Albiero, A.; Scevarolli, S.; Salvagno, G.L.; Franchi, M.; Guidi, G.C.
Evaluation of metalloproteinases 2 and 9 and their inhibitors in physiologic and pre-eclamptic pregnancy
J. Clin. Lab. Anal.
23
88-92
2009
Homo sapiens
Manually annotated by BRENDA team
Itoh, T.; Nakamura, H.; Kishi, J.; Hayakawa, T.
The activation of matrix metalloproteinases by a whole-cell extract from Prevotella nigrescens
J. Endod.
35
55-59
2009
Homo sapiens
Manually annotated by BRENDA team
Zhao, X.; Town, J.R.; Li, F.; Zhang, X.; Cockcroft, D.W.; Gordon, J.R.
ELR-CXC chemokine receptor antagonism targets inflammatory responses at multiple levels
J. Immunol.
182
3213-3222
2009
Homo sapiens
Manually annotated by BRENDA team
Bilousova, T.V.; Dansie, L.; Ngo, M.; Aye, J.; Charles, J.R.; Ethell, D.W.; Ethell, I.M.
Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model
J. Med. Genet.
46
94-102
2009
Mus musculus
Manually annotated by BRENDA team
De Stefano, D.; Nicolaus, G.; Maiuri, M.C.; Cipolletta, D.; Galluzzi, L.; Cinelli, M.P.; Tajana, G.; Iuvone, T.; Carnuccio, R.
NF-kappaB blockade upregulates Bax, TSP-1, and TSP-2 expression in rat granulation tissue
J. Mol. Med.
87
481-492
2009
Rattus norvegicus
Manually annotated by BRENDA team
Chung, I.M.; Ahmad, A.; Ali, M.; Lee, O.K.; Kim, M.Y.; Kim, J.H.; Yoon, D.Y.; Peebles, C.A.; San, K.Y.
Flavonoid glucosides from the hairy roots of Catharanthus roseus
J. Nat. Prod.
72
613-620
2009
Homo sapiens
Manually annotated by BRENDA team
Santra, M.; Santra, S.; Roberts, C.; Zhang, R.L.; Chopp, M.
Doublecortin induces mitotic microtubule catastrophe and inhibits glioma cell invasion
J. Neurochem.
108
231-245
2009
Homo sapiens
Manually annotated by BRENDA team
Castillo, J.; Alvarez-Sabin, J.; Martinez-Vila, E.; Montaner, J.; Sobrino, T.; Vivancos, J.; Vivancos, J.
Inflammation markers and prediction of post-stroke vascular disease recurrence: the MITICO study
J. Neurol.
256
217-224
2009
Homo sapiens
Manually annotated by BRENDA team
Kwon, I.; Kim, E.H.; del Zoppo, G.J.; Heo, J.H.
Ultrastructural and temporal changes of the microvascular basement membrane and astrocyte interface following focal cerebral ischemia
J. Neurosci. Res.
87
668-676
2009
Rattus norvegicus
Manually annotated by BRENDA team
Dai, J.P.; Chen, J.; Bei, Y.F.; Han, B.X.; Wang, S.
Influence of borneol on primary mice oral fibroblasts: a penetration enhancer may be used in oral submucous fibrosis
J. Oral Pathol. Med.
38
276-281
2009
Mus musculus
Manually annotated by BRENDA team
Dai, J.; Louedec, L.; Philippe, M.; Michel, J.B.; Houard, X.
Effect of blocking platelet activation with AZD6140 on development of abdominal aortic aneurysm in a rat aneurysmal model
J. Vasc. Surg.
49
719-727
2009
Rattus norvegicus
Manually annotated by BRENDA team
Poyer, F.; Coquerel, B.; Pegahi, R.; Cazin, L.; Norris, V.; Vannier, J.P.; Lamacz, M.
Secretion of MMP-2 and MMP-9 induced by VEGF autocrine loop correlates with clinical features in childhood acute lymphoblastic leukemia
Leuk. Res.
33
407-417
2009
Homo sapiens
Manually annotated by BRENDA team
Sen, T.; Moulik, S.; Dutta, A.; Choudhury, P.R.; Banerji, A.; Das, S.; Roy, M.; Chatterjee, A.
Multifunctional effect of epigallocatechin-3-gallate (EGCG) in downregulation of gelatinase-A (MMP-2) in human breast cancer cell line MCF-7
Life Sci.
84
194-204
2009
Homo sapiens
Manually annotated by BRENDA team
Solakivi, T.; Kunnas, T.; Kaerkkaeinen, S.; Jaakkola, O.; Nikkari, S.T.
Arachidonic acid increases matrix metalloproteinase 9 secretion and expression in human monocytic MonoMac 6 cells
Lipids Health Dis.
8
11
2009
Homo sapiens
Manually annotated by BRENDA team
Cheng, Y.C.; Chen, L.M.; Chang, M.H.; Chen, W.K.; Tsai, F.J.; Tsai, C.H.; Lai, T.Y.; Kuo, W.W.; Huang, C.Y.; Liu, C.J.
Lipopolysaccharide upregulates uPA, MMP-2 and MMP-9 via ERK1/2 signaling in H9c2 cardiomyoblast cells
Mol. Cell. Biochem.
325
15-23
2009
Rattus norvegicus
Manually annotated by BRENDA team
Leung, J.C.; Chan, L.Y.; Tam, K.Y.; Tang, S.C.; Lam, M.F.; Cheng, A.S.; Chu, K.M.; Lai, K.N.
Regulation of CCN2/CTGF and related cytokines in cultured peritoneal cells under conditions simulating peritoneal dialysis
Nephrol. Dial. Transplant.
24
458-469
2009
Homo sapiens
Manually annotated by BRENDA team
Ranasinghe, H.S.; Williams, C.E.; Christophidis, L.J.; Mitchell, M.D.; Fraser, M.; Scheepens, A.
Proteolytic activity during cortical development is distinct from that involved in hypoxic ischemic injury
Neuroscience
158
732-744
2009
Rattus norvegicus
Manually annotated by BRENDA team
Roomi, M.W.; Monterrey, J.C.; Kalinovsky, T.; Rath, M.; Niedzwiecki, A.
Distinct patterns of matrix metalloproteinase-2 and -9 expression in normal human cell lines
Oncol. Rep.
21
821-826
2009
Homo sapiens
Manually annotated by BRENDA team
Acera, A.; Rocha, G.; Vecino, E.; Lema, I.; Duran, J.A.
Inflammatory markers in the tears of patients with ocular surface disease
Ophthalmic Res.
40
315-321
2008
Homo sapiens
Manually annotated by BRENDA team
Vairaktaris, E.; Serefoglou, Z.; Avgoustidis, D.; Yapijakis, C.; Critselis, E.; Vylliotis, A.; Spyridonidou, S.; Derka, S.; Vassiliou, S.; Nkenke, E.; Patsouris, E.
Gene polymorphisms related to angiogenesis, inflammation and thrombosis that influence risk for oral cancer
Oral Oncol.
45
247-253
2009
Homo sapiens
Manually annotated by BRENDA team
Carneiro, E.; Menezes, R.; Garlet, G.P.; Garcia, R.B.; Bramante, C.M.; Figueira, R.; Sogayar, M.; Granjeiro, J.M.
Expression analysis of matrix metalloproteinase-9 in epithelialized and nonepithelialized apical periodontitis lesions
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod.
107
127-132
2009
Homo sapiens
Manually annotated by BRENDA team
Lee, J.I.; Jin, B.H.; Kim, M.A.; Yoon, H.J.; Hong, S.P.; Hong, S.D.
Prognostic significance of CXCR-4 expression in oral squamous cell carcinoma
Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod.
107
678-684
2009
Homo sapiens
Manually annotated by BRENDA team
Baba, H.; Ohtsuka, Y.; Fujii, T.; Haruna, H.; Nagata, S.; Kobayashi, H.; Yamataka, A.; Shimizu, T.; Miyano, T.; Yamashiro, Y.
Immunological investigation of the hepatic tissue from infants with biliary atresia
Pediatr. Surg. Int.
25
157-162
2009
Homo sapiens
Manually annotated by BRENDA team
Seeger, F.H.; Chen, L.; Spyridopoulos, I.; Altschmied, J.; Aicher, A.; Haendeler, J.
Downregulation of ETS rescues diabetes-induced reduction of endothelial progenitor cells
PLoS ONE
4
e4529
2009
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Higashimoto, Y.; Iwata, T.; Okada, M.; Satoh, H.; Fukuda, K.; Tohda, Y.
Serum biomarkers as predictors of lung function decline in chronic obstructive pulmonary disease
Respir. Med.
103
1231-1238
2009
Homo sapiens
Manually annotated by BRENDA team
Barlas, I.O.; Sezgin, M.; Erdal, M.E.; Sahin, G.; Ankarali, H.C.; Altintas, Z.M.; Tuerkmen, E.
Association of (-1,607) 1G/2G polymorphism of matrix metalloproteinase-1 gene with knee osteoarthritis in the Turkish population (knee osteoarthritis and MMPs gene polymorphisms)
Rheumatol. Int.
29
383-388
2009
Homo sapiens
Manually annotated by BRENDA team
Borthwick, L.A.; Parker, S.M.; Brougham, K.A.; Johnson, G.E.; Gorowiec, M.R.; Ward, C.; Lordan, J.; Corris, P.; Kirby, J.A.; Fisher, A.J.
Epithelial to mesenchymal transition (EMT) and airway remodelling after human lung transplantation
Thorax
64
770-777
2009
Homo sapiens
Manually annotated by BRENDA team
Yeh, M.H.; Kao, S.T.; Hung, C.M.; Liu, C.J.; Lee, K.H.; Yeh, C.C.
Hesperidin inhibited acetaldehyde-induced matrix metalloproteinase-9 gene expression in human hepatocellular carcinoma cells
Toxicol. Lett.
184
204-210
2009
Homo sapiens
Manually annotated by BRENDA team
Meng, D.; Lv, D.D.; Zhuang, X.; Sun, H.; Fan, L.; Shi, X.L.; Fang, J.
Benzo[a]pyrene induces expression of matrix metalloproteinases and cell migration and invasion of vascular smooth muscle cells
Toxicol. Lett.
184
44-49
2009
Rattus norvegicus
Manually annotated by BRENDA team
Sander, A.L.; Henrich, D.; Muth, C.M.; Marzi, I.; Barker, J.H.; Frank, J.M.
In vivo effect of hyperbaric oxygen on wound angiogenesis and epithelialization
Wound Repair Regen.
17
179-184
2009
Mus musculus
Manually annotated by BRENDA team
Romana-Souza, B.; Santos, J.S.; Monte-Alto-Costa, A.
Beta-1 and beta-2, but not alpha-1 and alpha-2, adrenoceptor blockade delays rat cutaneous wound healing
Wound Repair Regen.
17
230-239
2009
Rattus norvegicus
Manually annotated by BRENDA team
Yanti, H.K.; Lee, M.; Kim, D.; Hwang, J.K.
Inhibitory effect of panduratin A on c-Jun N-terminal kinase and activator protein-1 signaling involved in Porphyromonas gingivalis supernatant-stimulated matrix metalloproteinase-9 expression in human oral epidermoid cells
Biol. Pharm. Bull.
32
1770-1775
2009
Homo sapiens
Manually annotated by BRENDA team
Piao, M.S.; Lee, J.K.; Park, C.S.; Ryu, H.S.; Kim, S.H.; Kim, H.S.
Early activation of matrix metalloproteinase-9 is associated with blood-brain barrier disruption after photothrombotic cerebral ischemia in rats
Acta Neurochir. (Wien)
151
1649-1653
2009
Rattus norvegicus
Manually annotated by BRENDA team
Hamada, T.; Duarte, S.; Tsuchihashi, S.; Busuttil, R.W.; Coito, A.J.
Inducible nitric oxide synthase deficiency impairs matrix metalloproteinase-9 activity and disrupts leukocyte migration in hepatic ischemia/reperfusion injury
Am. J. Pathol.
174
2265-2277
2009
Mus musculus
Manually annotated by BRENDA team
Garg, P.; Vijay-Kumar, M.; Wang, L.; Gewirtz, A.T.; Merlin, D.; Sitaraman, S.V.
Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis
Am. J. Physiol. Gastrointest. Liver Physiol.
296
G175-G184
2009
Mus musculus
Manually annotated by BRENDA team
Grierson, C.; Miller, D.; Lapan, P.; Brady, J.
Utility of combining MMP-9 ELISA and MMP-9 activity assay data to monitor plasma enzyme specific-activity
Anal. Biochem.
404
232-234
2010
Homo sapiens
Manually annotated by BRENDA team
Lee, T.Y.; Lee, K.J.; Baik, H.S.
Expression of IL-1beta, MMP-9 and TIMP-1 on the pressure side of gingiva under orthodontic loading
Angle Orthod.
79
733-739
2009
Rattus norvegicus
Manually annotated by BRENDA team
Zyada, M.M.
Expression of matrix metalloproteinase-9 and significance of a macrophage assay in eosinophilic granuloma
Ann. Diagn. Pathol.
13
367-372
2009
Homo sapiens
Manually annotated by BRENDA team
Choi, M.S.; Cho, K.S.; Shin, S.M.; Ko, H.M.; Kwon, K.J.; Shin, C.Y.; Ko, K.H.
ATP induced microglial cell migration through non-transcriptional activation of matrix metalloproteinase-9
Arch. Pharm. Res.
33
257-265
2010
Mus musculus
Manually annotated by BRENDA team
Huang, P.H.; Chen, Y.H.; Wang, C.H.; Chen, J.S.; Tsai, H.Y.; Lin, F.Y.; Lo, W.Y.; Wu, T.C.; Sata, M.; Chen, J.W.; Lin, S.J.
Matrix metalloproteinase-9 is essential for ischemia-induced neovascularization by modulating bone marrow-derived endothelial progenitor cells
Arterioscler. Thromb. Vasc. Biol.
29
1179-1184
2009
Mus musculus
Manually annotated by BRENDA team
Chang, C.J.; Hsu, L.A.; Ko, Y.H.; Chen, P.L.; Chuang, Y.T.; Lin, C.Y.; Liao, C.H.; Pang, J.H.
Thrombin regulates matrix metalloproteinase-9 expression in human monocytes
Biochem. Biophys. Res. Commun.
385
241-246
2009
Homo sapiens
Manually annotated by BRENDA team
Jung, S.K.; Lee, K.W.; Kim, H.Y.; Oh, M.H.; Byun, S.; Lim, S.H.; Heo, Y.S.; Kang, N.J.; Bode, A.M.; Dong, Z.; Lee, H.J.
Myricetin suppresses UVB-induced wrinkle formation and MMP-9 expression by inhibiting Raf
Biochem. Pharmacol.
79
1455-1461
2010
Mus musculus
Manually annotated by BRENDA team
Gessi, S.; Sacchetto, V.; Fogli, E.; Merighi, S.; Varani, K.; Baraldi, P.G.; Tabrizi, M.A.; Leung, E.; Maclennan, S.; Borea, P.A.
Modulation of metalloproteinase-9 in U87MG glioblastoma cells by A3 adenosine receptors
Biochem. Pharmacol.
79
1483-1495
2010
Homo sapiens
Manually annotated by BRENDA team
Yanti, H.; Oh, H.I.; Anggakusuma, H.I.; Hwang, J.K.
Effects of panduratin A isolated from Kaempferia pandurata ROXB. on the expression of matrix metalloproteinase-9 by porphyromonas gingivalis supernatant-induced KB cells
Biol. Pharm. Bull.
32
110-115
2009
Homo sapiens
Manually annotated by BRENDA team
Xue, J.; Hua, Y.N.; Xie, M.L.; Gu, Z.L.
Aspirin inhibits MMP-9 mRNA expression and release via the PPARalpha/gamma and COX-2/mPGES-1-mediated pathways in macrophages derived from THP-1 cells
Biomed. Pharmacother.
64
118-123
2010
Homo sapiens
Manually annotated by BRENDA team
Wang, G.; Guo, Q.; Hossain, M.; Fazio, V.; Zeynalov, E.; Janigro, D.; Mayberg, M.R.; Namura, S.
Bone marrow-derived cells are the major source of MMP-9 contributing to blood-brain barrier dysfunction and infarct formation after ischemic stroke in mice
Brain Res.
1294
183-192
2009
Mus musculus
Manually annotated by BRENDA team
Tan, M.L.; Choong, P.F.; Dass, C.R.
Direct anti-metastatic efficacy by the DNA enzyme Dz13 and downregulated MMP-2, MMP-9 and MT1-MMP in tumours
Cancer Cell Int.
10
9-9
2010
Homo sapiens
Manually annotated by BRENDA team
Hung, W.C.; Tseng, W.L.; Shiea, J.; Chang, H.C.
Skp2 overexpression increases the expression of MMP-2 and MMP-9 and invasion of lung cancer cells
Cancer Lett.
288
156-161
2010
Homo sapiens
Manually annotated by BRENDA team
Takagi, S.; Simizu, S.; Osada, H.
RECK negatively regulates matrix metalloproteinase-9 transcription
Cancer Res.
69
1502-1508
2009
Homo sapiens
Manually annotated by BRENDA team
Massaro, M.; Zampolli, A.; Scoditti, E.; Carluccio, M.A.; Storelli, C.; Distante, A.; De Caterina, R.
Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability
Cardiovasc. Res.
86
311-320
2010
Homo sapiens
Manually annotated by BRENDA team
Mishra, P.K.; Metreveli, N.; Tyagi, S.C.
MMP-9 gene ablation and TIMP-4 mitigate PAR-1-mediated cardiomyocyte dysfunction: a plausible role of dicer and miRNA
Cell Biochem. Biophys.
57
67-76
2010
Mus musculus
Manually annotated by BRENDA team
Lin, C.C.; Kuo, C.T.; Cheng, C.Y.; Wu, C.Y.; Lee, C.W.; Hsieh, H.L.; Lee, I.T.; Yang, C.M.
IL-1beta promotes A549 cell migration via MAPKs/AP-1- and NF-kappaB-dependent matrix metalloproteinase-9 expression
Cell. Signal.
21
1652-1662
2009
Homo sapiens
Manually annotated by BRENDA team
Chen, Y.J.; Chang, W.M.; Liu, Y.W.; Lee, C.Y.; Jang, Y.H.; Kuo, C.D.; Liao, H.F.
A small-molecule metastasis inhibitor, norcantharidin, downregulates matrix metalloproteinase-9 expression by inhibiting Sp1 transcriptional activity in colorectal cancer cells
Chem. Biol. Interact.
181
440-446
2009
Homo sapiens
Manually annotated by BRENDA team
Chou, Y.C.; Sheu, J.R.; Chung, C.L.; Chen, C.Y.; Lin, F.L.; Hsu, M.J.; Kuo, Y.H.; Hsiao, G.
Nuclear-targeted inhibition of NF-kappaB on MMP-9 production by N-2-(4-bromophenyl) ethyl caffeamide in human monocytic cells
Chem. Biol. Interact.
184
403-412
2010
Homo sapiens
Manually annotated by BRENDA team
Lee, E.J.; Kim, S.Y.; Hyun, J.W.; Min, S.W.; Kim, D.H.; Kim, H.S.
Glycitein inhibits glioma cell invasion through down-regulation of MMP-3 and MMP-9 gene expression
Chem. Biol. Interact.
185
18-24
2010
Homo sapiens
Manually annotated by BRENDA team
He, Z.J.; Huang, Z.T.; Chen, X.T.; Zou, Z.J.
Effects of matrix metalloproteinase 9 inhibition on the blood brain barrier and inflammation in rats following cardiopulmonary resuscitation
Chin. Med. Sci.
122
2346-2351
2009
Rattus norvegicus
Manually annotated by BRENDA team
Sakata, K.; Hamaoka, K.; Ozawa, S.; Niboshi, A.; Yahata, T.; Fujii, M.; Hamaoka, A.; Toiyama, K.; Nishida, M.; Itoi, T.
Matrix metalloproteinase-9 in vascular lesions and endothelial regulation in Kawasaki disease
Circ. J.
74
1670-1675
2010
Homo sapiens
Manually annotated by BRENDA team
Gai, X.; Lan, X.; Luo, Z.; Wang, F.; Liang, Y.; Zhang, H.; Zhang, W.; Hou, J.; Huang, M.
Association of MMP-9 gene polymorphisms with atrial fibrillation in hypertensive heart disease patients
Clin. Chim. Acta
408
105-109
2009
Homo sapiens
Manually annotated by BRENDA team
Marcaccini, A.M.; Novaes, A.B.; Meschiari, C.A.; Souza, S.L.; Palioto, D.B.; Sorgi, C.A.; Faccioli, L.H.; Tanus-Santos, J.E.; Gerlach, R.F.
Circulating matrix metalloproteinase-8 (MMP-8) and MMP-9 are increased in chronic periodontal disease and decrease after non-surgical periodontal therapy
Clin. Chim. Acta
409
117-122
2009
Homo sapiens
Manually annotated by BRENDA team
Lau, A.C.; Duong, T.T.; Ito, S.; Wilson, G.J.; Yeung, R.S.
Inhibition of matrix metalloproteinase-9 activity improves coronary outcome in an animal model of Kawasaki disease
Clin. Exp. Immunol.
157
300-309
2009
Mus musculus
Manually annotated by BRENDA team
Anand, S.P.; Selvaraj, P.
Effect of 1, 25 dihydroxyvitamin D(3) on matrix metalloproteinases MMP-7, MMP-9 and the inhibitor TIMP-1 in pulmonary tuberculosis
Clin. Immunol.
133
126-131
2009
Homo sapiens
Manually annotated by BRENDA team
Zhao, S.; Choksuchat, C.; Zhao, Y.; Ballagh, S.A.; Kovalevsky, G.A.; Archer, D.F.
Effects of doxycycline on serum and endometrial levels of MMP-2, MMP-9 and TIMP-1 in women using a levonorgestrel-releasing subcutaneous implant
Contraception
79
469-478
2009
Homo sapiens
Manually annotated by BRENDA team
Dong, X.; Song, Y.N.; Liu, W.G.; Guo, X.L.
MMP-9, a potential target for cerebral ischemic treatment
Curr. Neuropharmacol.
7
269-275
2009
Homo sapiens
Manually annotated by BRENDA team
Sochor, M.; Richter, S.; Schmidt, A.; Hempel, S.; Hopt, U.T.; Keck, T.
Inhibition of matrix metalloproteinase-9 with doxycycline reduces pancreatitis-associated lung injury
Digestion
80
65-73
2009
Rattus norvegicus
Manually annotated by BRENDA team
Yamaguchi, M.; Hayashi, M.; Fujita, S.; Yoshida, T.; Utsunomiya, T.; Yamamoto, H.; Kasai, K.
Low-energy laser irradiation facilitates the velocity of tooth movement and the expressions of matrix metalloproteinase-9, cathepsin K, and alpha(v) beta(3) integrin in rats
Eur. J. Orthod.
32
131-139
2010
Rattus norvegicus
Manually annotated by BRENDA team
Pan, M.H.; Lin, Y.T.; Lin, C.L.; Wei, C.S.; Ho, C.T.; Chen, W.J.
Suppression of heregulin-beta1/HER2-modulated invasive and aggressive phenotype of breast carcinoma by pterostilbene via inhibition of matrix metalloproteinase-9, p38 kinase cascade and Akt activation
Evid. Based. Complement Alternat. Med.
2011
562187
2011
Homo sapiens
Manually annotated by BRENDA team
Nogueira de Melo, A.C.; de Souza, E.P.; Elias, C.G.; dos Santos, A.L.; Branquinha, M.H.; dAvila-Levy, C.M.; dos Reis, F.C.; Costa, T.F.; Lima, A.P.; de Souza Pereira, M.C.; Meirelles, M.N.; Vermelho, A.B.
Detection of matrix metallopeptidase-9-like proteins in Trypanosoma cruzi
Exp. Parasitol.
125
256-263
2010
Trypanosoma cruzi, Trypanosoma cruzi Y
Manually annotated by BRENDA team
Mroczko, B.; Lukaszewicz-Zajac, M.; Guzinska-Ustymowicz, K.; Gryko, M.; Czyzewska, J.; Kemona, A.; Kedra, B.; Szmitkowski, M.
Expression of matrix metalloproteinase-9 in the neoplastic and interstitial inflammatory infiltrate cells in gastric cancer
Folia Histochem. Cytobiol.
47
491-496
2009
Homo sapiens
Manually annotated by BRENDA team
Kim, S.C.; Magesh, V.; Jeong, S.J.; Lee, H.J.; Ahn, K.S.; Lee, H.J.; Lee, E.O.; Kim, S.H.; Lee, M.H.; Kim, J.H.; Kim, S.H.
Ethanol extract of Ocimum sanctum exerts anti-metastatic activity through inactivation of matrix metalloproteinase-9 and enhancement of anti-oxidant enzymes
Food Chem. Toxicol.
48
1478-1482
2010
Mus musculus
Manually annotated by BRENDA team
Choi, J.H.; Han, E.H.; Hwang, Y.P.; Choi, J.M.; Choi, C.Y.; Chung, Y.C.; Seo, J.K.; Jeong, H.G.
Suppression of PMA-induced tumor cell invasion and metastasis by aqueous extract isolated from Prunella vulgaris via the inhibition of NF-kappaB-dependent MMP-9 expression
Food Chem. Toxicol.
48
564-571
2010
Homo sapiens, Mus musculus
Manually annotated by BRENDA team
Li, H.; Mittal, A.; Makonchuk, D.Y.; Bhatnagar, S.; Kumar, A.
Matrix metalloproteinase-9 inhibition ameliorates pathogenesis and improves skeletal muscle regeneration in muscular dystrophy
Hum. Mol. Genet.
18
2584-2598
2009
Mus musculus
Manually annotated by BRENDA team
Qiu, Z.; Dillen, C.; Hu, J.; Verbeke, H.; Struyf, S.; Van Damme, J.; Opdenakker, G.
Interleukin-17 regulates chemokine and gelatinase B expression in fibroblasts to recruit both neutrophils and monocytes
Immunobiology
214
835-842
2009
Mus musculus
Manually annotated by BRENDA team
Kolaczkowska, E.; Koziol, A.; Plytycz, B.; Arnold, B.; Opdenakker, G.
Altered apoptosis of inflammatory neutrophils in MMP-9-deficient mice is due to lower expression and activity of caspase-3
Immunol. Lett.
126
73-82
2009
Mus musculus
Manually annotated by BRENDA team
Heilpern, A.J.; Wertheim, W.; He, J.; Perides, G.; Bronson, R.T.; Hu, L.T.
Matrix metalloproteinase 9 plays a key role in lyme arthritis but not in dissemination of Borrelia burgdorferi
Infect. Immun.
77
2643-2649
2009
Mus musculus
Manually annotated by BRENDA team
Yiqin, Y.; Meilin, X.; Jie, X.; Keping, Z.
Aspirin inhibits MMP-2 and MMP-9 expression and activity through PPARalpha/gamma and TIMP-1-mediated mechanisms in cultured mouse celiac macrophages
Inflammation
32
233-241
2009
Mus musculus
Manually annotated by BRENDA team
Liu, D.S.; Wang, T.; Han, S.X.; Dong, J.J.; Liao, Z.L.; He, G.M.; Chen, L.; Chen, Y.J.; Xu, D.; Hou, Y.; Li, Y.P.; Wen, F.Q.
p38 MAPK and MMP-9 cooperatively regulate mucus overproduction in mice exposed to acrolein fog
Int. Immunopharmacol.
9
1228-1235
2009
Mus musculus
Manually annotated by BRENDA team
Hwang, M.K.; Song, N.R.; Kang, N.J.; Lee, K.W.; Lee, H.J.
Activation of phosphatidylinositol 3-kinase is required for tumor necrosis factor-alpha-induced upregulation of matrix metalloproteinase-9: its direct inhibition by quercetin
Int. J. Biochem. Cell Biol.
41
1592-1600
2009
Mus musculus
Manually annotated by BRENDA team
Bittner, A.; Alcaino, H.; Castro, P.F.; Perez, O.; Corbalan, R.; Troncoso, R.; Chiong, M.; Mellado, R.; Moraga, F.; Zanolli, D.; Winter, J.L.; Zamorano, J.J.; Diaz-Araya, G.; Lavandero, S.
Matrix metalloproteinase-9 activity is associated to oxidative stress in patients with acute coronary syndrome
Int. J. Cardiol.
143
98-100
2009
Homo sapiens
Manually annotated by BRENDA team
Huang, Z.; Wang, L.; Meng, S.; Wang, Y.; Chen, T.; Wang, C.
Berberine reduces both MMP-9 and EMMPRIN expression through prevention of p38 pathway activation in PMA-induced macrophages
Int. J. Cardiol.
146
153-158
2009
Homo sapiens
Manually annotated by BRENDA team
Tagami, K.; Yujiri, T.; Takahashi, T.; Kizuki, N.; Tanaka, Y.; Mitani, N.; Nakamura, Y.; Ariyoshi, K.; Ando, T.; Gondo, T.; Tanizawa, Y.
Increased serum levels of matrix metalloproteinase-9 in acute graft-versus-host disease after allogeneic haematopoietic stem cell transplantation
Int. J. Hematol.
90
248-252
2009
Homo sapiens
Manually annotated by BRENDA team
Aktas, Z.; Gurelik, G.; Goecuen, P.U.; Akyuerek, N.; Onol, M.; Hasanreisoglu, B.
Matrix metalloproteinase-9 expression in retinal ganglion cell layer and effect of topically applied brimonidine tartrate 0.2% therapy on this expression in an endothelin-1-induced optic nerve ischemia model
Int. Ophthalmol.
30
253-259
2010
Oryctolagus cuniculus
Manually annotated by BRENDA team
Cauwe, B.; Martens, E.; Proost, P.; Opdenakker, G.
Multidimensional degradomics identifies systemic autoantigens and intracellular matrix proteins as novel gelatinase B/MMP-9 substrates
Integr. Biol. (Camb.)
1
404-426
2009
Homo sapiens
Manually annotated by BRENDA team
Takagi, H.; Manabe, H.; Kawai, N.; Goto, S.N.; Umemoto, T.
Circulating matrix metalloproteinase-9 concentrations and abdominal aortic aneurysm presence: a meta-analysis
Interact. Cardiovasc. Thorac. Surg.
9
437-440
2009
Homo sapiens
Manually annotated by BRENDA team
Chotikavanich, S.; de Paiva, C.S.; Li, d.e..Q.; Chen, J.J.; Bian, F.; Farley, W.J.; Pflugfelder, S.C.
Production and activity of matrix metalloproteinase-9 on the ocular surface increase in dysfunctional tear syndrome
Invest. Ophthalmol. Vis. Sci.
50
3203-3209
2009
Homo sapiens
Manually annotated by BRENDA team
Kuo, P.T.; Lin, T.P.; Liu, L.C.; Huang, C.H.; Lin, J.K.; Kao, J.Y.; Way, T.D.
Penta-O-galloyl-beta-D-glucose suppresses prostate cancer bone metastasis by transcriptionally repressing EGF-induced MMP-9 expression
J. Agric. Food Chem.
57
3331-3339
2009
Homo sapiens
Manually annotated by BRENDA team
Sessions, D.R.; Vick, M.M.; Fitzgerald, B.P.
Characterization of matrix metalloproteinase-2 and matrix metalloproteinase-9 and their inhibitors in equine granulosa cells in vivo and in vitro
J. Anim. Sci.
87
3955-3966
2009
Equus caballus
Manually annotated by BRENDA team
Ardi, V.C.; Van den Steen, P.E.; Opdenakker, G.; Schweighofer, B.; Deryugina, E.I.; Quigley, J.P.
Neutrophil MMP-9 proenzyme, unencumbered by TIMP-1, undergoes efficient activation in vivo and catalytically induces angiogenesis via a basic fibroblast growth factor (FGF-2)/FGFR-2 pathway
J. Biol. Chem.
284
25854-25866
2009
Homo sapiens
Manually annotated by BRENDA team
Tsai, C.C.; Tzang, B.S.; Chiang, S.Y.; Hsu, G.J.; Hsu, T.C.
Increased expression of Matrix Metalloproteinase 9 in liver from NZB/W F1 mice received antibody against human parvovirus B19 VP1 unique region protein
J. Biomed. Sci.
16
14
2009
Mus musculus
Manually annotated by BRENDA team
Tyagi, N.; Gillespie, W.; Vacek, J.C.; Sen, U.; Tyagi, S.C.; Lominadze, D.
Activation of GABA-A receptor ameliorates homocysteine-induced MMP-9 activation by ERK pathway
J. Cell. Physiol.
220
257-266
2009
Mus musculus
Manually annotated by BRENDA team
Gao, P.; Zhu, Y.; Ling, F.; Shen, F.; Lee, B.; Gabriel, R.A.; Hao, Q.; Yang, G.Y.; Su, H.; Young, W.L.
Nonischemic cerebral venous hypertension promotes a pro-angiogenic stage through HIF-1 downstream genes and leukocyte-derived MMP-9
J. Cereb. Blood Flow Metab.
29
1482-1490
2009
Mus musculus
Manually annotated by BRENDA team
Gaudet, J.G.; Yocum, G.T.; Lee, S.S.; Granat, A.; Mikami, M.; Connolly, E.S.; Heyer, E.J.
MMP-9 levels in elderly patients with cognitive dysfunction after carotid surgery
J. Clin. Neurosci.
17
436-440
2010
Homo sapiens
Manually annotated by BRENDA team
Montreekachon, P.; Chotjumlong, P.; Reutrakul, V.; Krisanaprakornkit, S.
Involvement of cytosolic phospholipase A2alpha in MMP-9 up-regulation
J. Dent. Res.
88
1031-1036
2009
Homo sapiens
Manually annotated by BRENDA team
Yanti, S.C.; Anggakusuma, S.C.; Gwon, S.H.; Hwang, J.K.
Kaempferia pandurata Roxb. inhibits Porphyromonas gingivalis supernatant-induced matrix metalloproteinase-9 expression via signal transduction in human oral epidermoid cells
J. Ethnopharmacol.
123
315-324
2009
Homo sapiens
Manually annotated by BRENDA team
Kim, S.; Kim, S.H.; Hur, S.M.; Lee, S.K.; Kim, W.W.; Kim, J.S.; Kim, J.H.; Choe, J.H.; Nam, S.J.; Lee, J.E.; Yang, J.H.
Silibinin prevents TPA-induced MMP-9 expression by down-regulation of COX-2 in human breast cancer cells
J. Ethnopharmacol.
126
252-257
2009
Homo sapiens
Manually annotated by BRENDA team
Liu, G.; Wang, B.; Zhang, J.; Jiang, H.; Liu, F.
Total panax notoginsenosides prevent atherosclerosis in apolipoprotein E-knockout mice: Role of downregulation of CD40 and MMP-9 expression
J. Ethnopharmacol.
126
350-354
2009
Mus musculus
Manually annotated by BRENDA team
Sheng, F.; Cheng, L.; Zeng, Q.; Gao, W.
Increased expression and activity of MMP-9 in C-reactive protein-induced human THP-1 mononuclear cells is related to activation of nuclear factor kappa-B
J. Huazhong Univ. Sci. Technol. Med. Sci.
29
399-403
2009
Homo sapiens
Manually annotated by BRENDA team
De Paiva, C.S.; Yoon, K.C.; Pangelinan, S.B.; Pham, S.; Puthenparambil, L.M.; Chuang, E.Y.; Farley, W.J.; Stern, M.E.; Li, D.Q.; Pflugfelder, S.C.
Cleavage of functional IL-2 receptor alpha chain (CD25) from murine corneal and conjunctival epithelia by MMP-9
J. Inflamm.
6
31
2009
Mus musculus
Manually annotated by BRENDA team
Lolmede, K.; Campana, L.; Vezzoli, M.; Bosurgi, L.; Tonlorenzi, R.; Clementi, E.; Bianchi, M.E.; Cossu, G.; Manfredi, A.A.; Brunelli, S.; Rovere-Querini, P.
Inflammatory and alternatively activated human macrophages attract vessel-associated stem cells, relying on separate HMGB1- and MMP-9-dependent pathways
J. Leukoc. Biol.
85
779-787
2009
Homo sapiens
Manually annotated by BRENDA team
Zambuzzi, W.F.; Paiva, K.B.; Menezes, R.; Oliveira, R.C.; Taga, R.; Granjeiro, J.M.
MMP-9 and CD68(+) cells are required for tissue remodeling in response to natural hydroxyapatite
J. Mol. Histol.
40
301-309
2009
Rattus norvegicus
Manually annotated by BRENDA team
Catalan, V.; Gomez-Ambrosi, J.; Rodriguez, A.; Ramirez, B.; Silva, C.; Rotellar, F.; Gil, M.J.; Cienfuegos, J.A.; Salvador, J.; Fruehbeck, G.
Increased adipose tissue expression of lipocalin-2 in obesity is related to inflammation and matrix metalloproteinase-2 and metalloproteinase-9 activities in humans
J. Mol. Med.
87
803-813
2009
Homo sapiens
Manually annotated by BRENDA team
Liu, W.; Hendren, J.; Qin, X.J.; Shen, J.; Liu, K.J.
Normobaric hyperoxia attenuates early blood-brain barrier disruption by inhibiting MMP-9-mediated occludin degradation in focal cerebral ischemia
J. Neurochem.
108
811-820
2009
Rattus norvegicus
Manually annotated by BRENDA team
Fernandes, K.S.; Brum, D.G.; Sandrim, V.C.; Guerreiro, C.T.; Barreira, A.A.; Tanus-Santos, J.E.
Matrix metalloproteinase-9 genotypes and haplotypes are associated with multiple sclerosis and with the degree of disability of the disease
J. Neuroimmunol.
214
128-131
2009
Homo sapiens
Manually annotated by BRENDA team
Pul, R.; Kopadze, T.; Skripuletz, T.; Voss, E.V.; Kieseier, B.C.; Stangel, M.
Polyclonal immunoglobulins (IVIg) induce expression of MMP-9 in microglia
J. Neuroimmunol.
217
46-50
2009
Rattus norvegicus
Manually annotated by BRENDA team
Ichiyama, T.; Takahashi, Y.; Matsushige, T.; Kajimoto, M.; Fukunaga, S.; Furukawa, S.
Serum matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 levels in non-herpetic acute limbic encephalitis
J. Neurol.
256
1846-1850
2009
Homo sapiens
Manually annotated by BRENDA team
Amaro, S.; Obach, V.; Cervera, A.; Urra, X.; Gomez-Choco, M.; Planas, A.M.; Chamorro, A.
Course of matrix metalloproteinase-9 isoforms after the administration of uric acid in patients with acute stroke: a proof-of-concept study
J. Neurol.
256
651-656
2009
Homo sapiens
Manually annotated by BRENDA team
Liu, C.H.; You, Z.; Liu, C.M.; Kim, Y.R.; Whalen, M.J.; Rosen, B.R.; Liu, P.K.
Diffusion-weighted magnetic resonance imaging reversal by gene knockdown of matrix metalloproteinase-9 activities in live animal brains
J. Neurosci.
29
3508-3517
2009
Mus musculus (Q2M4J5)
Manually annotated by BRENDA team
Michaluk, P.; Mikasova, L.; Groc, L.; Frischknecht, R.; Choquet, D.; Kaczmarek, L.
Matrix metalloproteinase-9 controls NMDA receptor surface diffusion through integrin beta1 signaling
J. Neurosci.
29
6007-6012
2009
Rattus norvegicus
Manually annotated by BRENDA team
Reyes, R.; Guo, M.; Swann, K.; Shetgeri, S.U.; Sprague, S.M.; Jimenez, D.F.; Barone, C.M.; Ding, Y.
Role of tumor necrosis factor-alpha and matrix metalloproteinase-9 in blood-brain barrier disruption after peripheral thermal injury in rats
J. Neurosurg.
110
1218-1226
2009
Rattus norvegicus
Manually annotated by BRENDA team
Park, J.W.; Hong, J.S.; Lee, K.S.; Kim, H.Y.; Lee, J.J.; Lee, S.R.
Green tea polyphenol (-)-epigallocatechin gallate reduces matrix metalloproteinase-9 activity following transient focal cerebral ischemia
J. Nutr. Biochem.
21
1038-1044
2009
Mus musculus
Manually annotated by BRENDA team
Mizoguchi, H.; Takuma, K.; Fukuzaki, E.; Ibi, D.; Someya, E.; Akazawa, K.H.; Alkam, T.; Tsunekawa, H.; Mouri, A.; Noda, Y.; Nabeshima, T.; Yamada, K.
Matrix metalloprotease-9 inhibition improves amyloid beta-mediated cognitive impairment and neurotoxicity in mice
J. Pharmacol. Exp. Ther.
331
14-22
2009
Mus musculus
Manually annotated by BRENDA team
Kakimoto, K.; Takai, S.; Murano, M.; Ishida, K.; Yoda, Y.; Inoue, T.; Jin, D.; Umegaki, E.; Higuchi, K.
Significance of chymase-dependent matrix metalloproteinase-9 activation on indomethacin-induced small intestinal damages in rats
J. Pharmacol. Exp. Ther.
332
684-689
2010
Rattus norvegicus
Manually annotated by BRENDA team
Cuadrado, E.; Rosell, A.; Penalba, A.; Slevin, M.; Alvarez-Sabin, J.; Ortega-Aznar, A.; Montaner, J.
Vascular MMP-9/TIMP-2 and neuronal MMP-10 up-regulation in human brain after stroke: a combined laser microdissection and protein array study
J. Proteome Res.
8
3191-3197
2009
Homo sapiens
Manually annotated by BRENDA team
Thomas, A.C.; Newby, A.C.
Effect of matrix metalloproteinase-9 knockout on vein graft remodelling in mice
J. Vasc. Res.
47
299-308
2009
Mus musculus
Manually annotated by BRENDA team
Tian, W.; Kyriakides, T.R.
Matrix metalloproteinase-9 deficiency leads to prolonged foreign body response in the brain associated with increased IL-1beta levels and leakage of the blood-brain barrier
Matrix Biol.
28
148-159
2009
Mus musculus
Manually annotated by BRENDA team
Kyriakides, T.R.; Wulsin, D.; Skokos, E.A.; Fleckman, P.; Pirrone, A.; Shipley, J.M.; Senior, R.M.; Bornstein, P.
Mice that lack matrix metalloproteinase-9 display delayed wound healing associated with delayed reepithelization and disordered collagen fibrillogenesis
Matrix Biol.
28
65-73
2009
Mus musculus
Manually annotated by BRENDA team
Zhao, F.; Zhang, Q.; Kang, C.; Cui, X.; Wang, T.; Xu, P.; Zhou, X.; Liu, J.; Song, X.
Suppression of matrix metalloproteinase-9 expression by RNA interference inhibits SGC7901 gastric adenocarcinoma cell growth and invasion in vitro and in vivo
Med. Oncol.
27
774-784
2010
Homo sapiens
Manually annotated by BRENDA team
Madsen, E.L.; Bruun, J.M.; Skogstrand, K.; Hougaard, D.M.; Christiansen, T.; Richelsen, B.
Long-term weight loss decreases the nontraditional cardiovascular risk factors interleukin-18 and matrix metalloproteinase-9 in obese subjects
Metab. Clin. Exp.
58
946-953
2009
Homo sapiens
Manually annotated by BRENDA team
Zhi, H.; Wang, H.; Ren, L.; Shi, Z.; Peng, H.; Cui, L.; Ma, G.; Ye, X.; Feng, Y.; Shen, C.; Zhai, X.; Zhang, C.; Zen, K.; Liu, N.
Functional polymorphisms of matrix metallopeptidase-9 and risk of coronary artery disease in a Chinese population
Mol. Biol. Rep.
37
13-20
2010
Homo sapiens
Manually annotated by BRENDA team
Wilson, T.J.; Nannuru, K.C.; Singh, R.K.
Cathepsin G-mediated activation of pro-matrix metalloproteinase 9 at the tumor-bone interface promotes transforming growth factor-beta signaling and bone destruction
Mol. Cancer Res.
7
1224-1233
2009
Mus musculus
Manually annotated by BRENDA team
Cheng, Y.C.; Kuo, W.W.; Wu, H.C.; Lai, T.Y.; Wu, C.H.; Hwang, J.M.; Wang, W.H.; Tsai, F.J.; Yang, J.J.; Huang, C.Y.; Chu, C.H.
ZAK induces MMP-2 activity via JNK/p38 signals and reduces MMP-9 activity by increasing TIMP-1/2 expression in H9c2 cardiomyoblast cells
Mol. Cell. Biochem.
325
69-77
2009
Homo sapiens
Manually annotated by BRENDA team
Pavlaki, M.; Giannopoulou, E.; Niarakis, A.; Ravazoula, P.; Aletras, A.J.
Walker 256 cancer cells secrete tissue inhibitor of metalloproteinase-free metalloproteinase-9
Mol. Cell. Biochem.
328
189-199
2009
Rattus norvegicus
Manually annotated by BRENDA team
Siskova, Z.; Yong, V.W.; Nomden, A.; van Strien, M.; Hoekstra, D.; Baron, W.
Fibronectin attenuates process outgrowth in oligodendrocytes by mislocalizing MMP-9 activity
Mol. Cell. Neurosci.
42
234-242
2009
Rattus norvegicus
Manually annotated by BRENDA team
Vaisar, T.; Kassim, S.Y.; Gomez, I.G.; Green, P.S.; Hargarten, S.; Gough, P.J.; Parks, W.C.; Wilson, C.L.; Raines, E.W.; Heinecke, J.W.
MMP-9 sheds the beta2 integrin subunit (CD18) from macrophages
Mol. Cell. Proteomics
8
1044-1060
2009
Mus musculus
Manually annotated by BRENDA team
Lee, H.; Park, J.W.; Kim, S.P.; Lo, E.H.; Lee, S.R.
Doxycycline inhibits matrix metalloproteinase-9 and laminin degradation after transient global cerebral ischemia
Neurobiol. Dis.
34
189-198
2009
Mus musculus
Manually annotated by BRENDA team
Kim, G.W.; Kim, H.J.; Cho, K.J.; Kim, H.W.; Cho, Y.J.; Lee, B.I.
The role of MMP-9 in integrin-mediated hippocampal cell death after pilocarpine-induced status epilepticus
Neurobiol. Dis.
36
169-180
2009
Mus musculus
Manually annotated by BRENDA team
Kim, S.Y.; Woo, M.S.; Park, J.S.; Kim, H.S.
Regulation of matrix metalloproteinase-9 gene expression in MPP+- or 6-OHDA-treated human neuroblastoma SK-N-BE(2)C cells
Neurochem. Int.
56
437-442
2010
Homo sapiens
Manually annotated by BRENDA team
Rybakowski, J.K.; Skibinska, M.; Leszczynska-Rodziewicz, A.; Kaczmarek, L.; Hauser, J.
Matrix metalloproteinase-9 gene and bipolar mood disorder
Neuromolecular Med.
11
128-132
2009
Homo sapiens
Manually annotated by BRENDA team
Cheng, G.; Zhang, X.; Gao, D.; Jiang, X.; Dong, W.
Resveratrol inhibits MMP-9 expression by up-regulating PPAR alpha expression in an oxygen glucose deprivation-exposed neuron model
Neurosci. Lett.
451
105-108
2009
Mus musculus
Manually annotated by BRENDA team
Joo, S.H.; Kwon, K.J.; Kim, J.W.; Kim, J.W.; Hasan, M.R.; Lee, H.J.; Han, S.H.; Shin, C.Y.
Regulation of matrix metalloproteinase-9 and tissue plasminogen activator activity by alpha-synuclein in rat primary glial cells
Neurosci. Lett.
469
352-356
2010
Rattus norvegicus
Manually annotated by BRENDA team
Hadassah, J.; Bhuvaneshwari, N.; Rao, U.; Sehgal, P.K.
Evaluation of succinylated collagen bandage lenses in corneal healing by the expression of matrix metalloproteinases (MMP-2 and MMP-9) in tear fluid
Ophthalmic Res.
42
64-72
2009
Homo sapiens
Manually annotated by BRENDA team
Liu, C.J.; Chang, K.W.; Lin, S.C.; Cheng, H.W.
Presurgical serum levels of matrix metalloproteinase-9 and vascular endothelial growth factor in oral squamous cell carcinoma
Oral Oncol.
45
920-925
2009
Homo sapiens
Manually annotated by BRENDA team
Annabi, B.; Lachambre, M.P.; Plouffe, K.; Moumdjian, R.; Beliveau, R.
Propranolol adrenergic blockade inhibits human brain endothelial cells tubulogenesis and matrix metalloproteinase-9 secretion
Pharmacol. Res.
60
438-445
2009
Homo sapiens
Manually annotated by BRENDA team
Kim, S.; Choi, J.H.; Lim, H.I.; Lee, S.K.; Kim, W.W.; Kim, J.S.; Kim, J.H.; Choe, J.H.; Yang, J.H.; Nam, S.J.; Lee, J.E.
Silibinin prevents TPA-induced MMP-9 expression and VEGF secretion by inactivation of the Raf/MEK/ERK pathway in MCF-7 human breast cancer cells
Phytomedicine
16
573-580
2009
Homo sapiens
Manually annotated by BRENDA team
Shinto, L.; Marracci, G.; Baldauf-Wagner, S.; Strehlow, A.; Yadav, V.; Stuber, L.; Bourdette, D.
Omega-3 fatty acid supplementation decreases matrix metalloproteinase-9 production in relapsing-remitting multiple sclerosis
Prostaglandins Leukot. Essent. Fatty Acids
80
131-136
2009
Homo sapiens
Manually annotated by BRENDA team
Konrad, L.; Scheiber, J.A.; Schwarz, L.; Schrader, A.J.; Hofmann, R.
TGF-beta1 and TGF-beta2 strongly enhance the secretion of plasminogen activator inhibitor-1 and matrix metalloproteinase-9 of the human prostate cancer cell line PC-3
Regul. Pept.
155
28-32
2009
Homo sapiens
Manually annotated by BRENDA team
Jiang, Z.; Sui, T.; Wang, B.
Relationships between MMP-2, MMP-9, TIMP-1 and TIMP-2 levels and their pathogenesis in patients with lupus nephritis
Rheumatol. Int.
30
1219-1226
2009
Homo sapiens
Manually annotated by BRENDA team
Rybakowski, J.K.; Skibinska, M.; Kapelski, P.; Kaczmarek, L.; Hauser, J.
Functional polymorphism of the matrix metalloproteinase-9 (MMP-9) gene in schizophrenia
Schizophr. Res.
109
90-93
2009
Homo sapiens
Manually annotated by BRENDA team
Park, K.P.; Rosell, A.; Foerch, C.; Xing, C.; Kim, W.J.; Lee, S.; Opdenakker, G.; Furie, K.L.; Lo, E.H.
Plasma and brain matrix metalloproteinase-9 after acute focal cerebral ischemia in rats
Stroke
40
2836-2842
2009
Rattus norvegicus
Manually annotated by BRENDA team
Fujimura, M.; Watanabe, M.; Narisawa, A.; Shimizu, H.; Tominaga, T.
Increased expression of serum matrix metalloproteinase-9 in patients with moyamoya disease
Surg. Neurol.
72
476-480
2009
Homo sapiens
Manually annotated by BRENDA team
Mikami, Y.; Dobschuetz, E.V.; Sommer, O.; Wellner, U.; Unno, M.; Hopt, U.; Keck, T.
Matrix metalloproteinase-9 derived from polymorphonuclear neutrophils increases gut barrier dysfunction and bacterial translocation in rat severe acute pancreatitis
Surgery
145
147-156
2009
Rattus norvegicus
Manually annotated by BRENDA team
Reiss, M.J.; Han, Y.P.; Garcia, E.; Goldberg, M.; Yu, H.; Garner, W.L.
Matrix metalloproteinase-9 delays wound healing in a murine wound model
Surgery
147
295-302
2010
Homo sapiens
Manually annotated by BRENDA team
Dias-Junior, C.A.; Cau, S.B.; Oliveira, A.M.; Castro, M.M.; Montenegro, M.F.; Gerlach, R.F.; Tanus-Santos, J.E.
Nitrite or sildenafil, but not BAY 41-2272, blunt acute pulmonary embolism-induced increases in circulating matrix metalloproteinase-9 and oxidative stress
Thromb. Res.
124
349-355
2009
Canis lupus familiaris
Manually annotated by BRENDA team
Rahko, E.; Kauppila, S.; Paeaekkoe, P.; Blanco, G.; Apaja-Sarkkinen, M.; Talvensaari-Mattila, A.; Turpeenniemi-Hujanen, T.; Jukkola, A.
Immunohistochemical study of matrix metalloproteinase 9 and tissue inhibitor of matrix metalloproteinase 1 in benign and malignant breast tissue--strong expression in intraductal carcinomas of the breast
Tumour Biol.
30
257-264
2009
Homo sapiens
Manually annotated by BRENDA team
Mandara, M.T.; Pavone, S.; Mandrioli, L.; Bettini, G.; Falzone, C.; Baroni, M.
Matrix metalloproteinase-2 and matrix metalloproteinase-9 expression in canine and feline meningioma
Vet. Pathol.
46
836-845
2009
Canis lupus familiaris, Felis catus
Manually annotated by BRENDA team
Kim, J.Y.; Choeng, H.C.; Ahn, C.; Cho, S.H.
Early and late changes of MMP-2 and MMP-9 in bleomycin-induced pulmonary fibrosis
Yonsei Med. J.
50
68-77
2009
Rattus norvegicus
Manually annotated by BRENDA team
Akers, W.J.; Xu, B.; Lee, H.; Sudlow, G.; Fields, G.B.; Achilefu, S.; Edwards, W.B.
Detection of MMP-2 and MMP-9 activity in vivo with a triple-helical peptide optical probe
Bioconjug. Chem.
23
656-663
2012
Homo sapiens
Manually annotated by BRENDA team
Oshitari, T.; Okuyama, Y.; Miyata, Y.; Kosano, H.; Takahashi, H.; Natsugari, H.
Nobiletin metabolites: synthesis and inhibitory activity against matrix metalloproteinase-9 production
Bioorg. Med. Chem. Lett.
21
4540-4544
2011
Homo sapiens
Manually annotated by BRENDA team
Cha, M.C.; Purslow, P.P.
The activities of MMP-9 and total gelatinase respond differently to substrate coating and cyclic mechanical stretching in fibroblasts and myoblasts
Cell Biol. Int.
34
587-591
2010
Rattus norvegicus
Manually annotated by BRENDA team
Tarr, G.P.; Williams, M.J.; Phillips, L.V.; van Rij, A.M.; Jones, G.T.
Pro-MMP-9/TIMP-1 ratio correlates poorly with a direct assessment of MMP-9 activity
Clin. Biochem.
44
1480-1482
2011
Homo sapiens
Manually annotated by BRENDA team
Ruggiero, E.; Toschi, E.; Federico, M.
The activity of matrix metalloproteinase-9 is part of the mechanism of cell-to-cell HIV-1 endocytosis in dendritic cells
Curr. Drug Discov. Technol.
8
112-118
2011
Homo sapiens
Manually annotated by BRENDA team
Franco, G.C.; Kajiya, M.; Nakanishi, T.; Ohta, K.; Rosalen, P.L.; Groppo, F.C.; Ernst, C.W.; Boyesen, J.L.; Bartlett, J.D.; Stashenko, P.; Taubman, M.A.; Kawai, T.
Inhibition of matrix metalloproteinase-9 activity by doxycycline ameliorates RANK ligand-induced osteoclast differentiation in vitro and in vivo
Exp. Cell Res.
317
1454-1464
2011
Mus musculus, Mus musculus BALB/c
Manually annotated by BRENDA team
Deziel, B.A.; Patel, K.; Neto, C.; Gottschall-Pass, K.; Hurta, R.A.
Proanthocyanidins from the American Cranberry (Vaccinium macrocarpon) inhibit matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in human prostate cancer cells via alterations in multiple cellular signalling pathways
J. Cell. Biochem.
111
742-754
2010
Homo sapiens
Manually annotated by BRENDA team
Awla, D.; Abdulla, A.; Syk, I.; Jeppsson, B.; Regner, S.; Thorlacius, H.
Neutrophil-derived matrix metalloproteinase-9 is a potent activator of trypsinogen in acinar cells in acute pancreatitis
J. Leukoc. Biol.
91
711-719
2011
Mus musculus, Mus musculus C57BL/6
Manually annotated by BRENDA team
Wang, J.; O'Sullivan, S.; Harmon, S.; Keaveny, R.; Radomski, M.W.; Medina, C.; Gilmer, J.F.
Design of barbiturate-nitrate hybrids that inhibit MMP-9 activity and secretion
J. Med. Chem.
55
2154-2162
2012
Homo sapiens
Manually annotated by BRENDA team
Perng, D.W.; Chang, K.T.; Su, K.C.; Wu, Y.C.; Chen, C.S.; Hsu, W.H.; Tsai, C.M.; Lee, Y.C.
Matrix metalloprotease-9 induces transforming growth factor-beta1 production in airway epithelium via activation of epidermal growth factor receptors
Life Sci.
89
204-212
2011
Homo sapiens
Manually annotated by BRENDA team
Rasch, M.G.; Lund, I.K.; Illemann, M.; H?yer-Hansen, G.; Gardsvoll, H.
Purification and characterization of recombinant full-length and protease domain of murine MMP-9 expressed in Drosophila S2 cells
Protein Expr. Purif.
72
87-94
2010
Mus musculus
Manually annotated by BRENDA team
Zaga-Clavellina, V.; Garcia-Lopez, G.; Flores-Pliego, A.; Merchant-Larios, H.; Vadillo-Ortega, F.
In vitro secretion and activity profiles of matrix metalloproteinases, MMP-9 and MMP-2, in human term extra-placental membranes after exposure to Escherichia coli
Reprod. Biol. Endocrinol.
9
13
2011
Homo sapiens
Manually annotated by BRENDA team
Patchigolla, R.; Knudson, W.; Schmid, T.
Matrix metalloproteinase-9 in a unique proteoglycan form in avian embryonic growth plate cartilage
Arch. Biochem. Biophys.
520
42-50
2012
Gallus gallus
Manually annotated by BRENDA team
Vandooren, J.; Born, B.; Solomonov, I.; Zajac, E.; Saldova, R.; Senske, M.; Ugarte-Berzal, E.; Martens, E.; Van Den Steen, P.; Van Damme, J.; Garcia-Pardo, A.; Froeyen, M.; Deryugina, E.; Quigley, J.; Moestrup, S.; Rudd, P.; Sagi, I.; Opdenakker, G.
Circular trimers of gelatinase B/matrix metalloproteinase-9 constitute a distinct population of functional enzyme molecules differentially regulated by tissue inhibitor of metalloproteinases-1
Biochem. J.
465
259-270
2015
Homo sapiens (P14780)
Manually annotated by BRENDA team
Zhu, G.; Kang, L.; Wei, Q.; Cui, X.; Wang, S.; Chen, Y.; Jiang, Y.
Expression and regulation of MMP1, MMP3, and MMP9 in the chicken ovary in response to gonadotropins, sex hormones, and TGFB1
Biol. Reprod.
90
57
2014
Gallus gallus (F1NGT3), Gallus gallus White leghorn (F1NGT3)
Manually annotated by BRENDA team
Musumeci, G.; Magro, G.; Cardile, V.; Coco, M.; Marzagalli, R.; Castrogiovanni, P.; Imbesi, R.; Graziano, A.; Barone, F.; Di Rosa, M.; Castorina, S.; Castorina, A.
Characterization of matrix metalloproteinase-2 and -9, ADAM-10 and N-cadherin expression in human glioblastoma multiforme
Cell Tissue Res.
362
45-60
2015
Homo sapiens (P14780)
Manually annotated by BRENDA team
Monsonego-Ornan, E.; Kosonovsky, J.; Bar, A.; Roth, L.; Fraggi-Rankis, V.; Simsa, S.; Kohl, A.; Sela-Donenfeld, D.
Matrix metalloproteinase 9/gelatinase B is required for neural crest cell migration
Dev. Biol.
364
162-177
2012
Gallus gallus, Gallus gallus Lohman
Manually annotated by BRENDA team
Sands, M.F.
Localization of matrix metalloproteinase (MMP)-9 in lung tissue of a murine model of allergic asthma
Immunol. Invest.
41
87-96
2012
Mus musculus (P41245), Mus musculus, Mus musculus C57BL/6 (P41245)
Manually annotated by BRENDA team
Bellini, T.; Trentini, A.; Manfrinato, M.; Tamborino, C.; Volta, C.; Di Foggia, V.; Fainardi, E.; Dallocchio, F.; Castellazzi, M.
Matrix metalloproteinase-9 activity detected in body fluids is the result of two different enzyme forms
J. Biochem.
151
493-499
2012
Homo sapiens (P14780)
Manually annotated by BRENDA team
Aston-Mourney, K.; Zraika, S.; Udayasankar, J.; Subramanian, S.; Green, P.; Kahn, S.; Hull, R.
Matrix metalloproteinase-9 reduces islet amyloid formation by degrading islet amyloid polypeptide
J. Biol. Chem.
288
3553-3559
2013
Homo sapiens (P14780), Homo sapiens, Mus musculus (P41245), Mus musculus, Mus musculus C57BL/6 x DBA/2 (P41245)
Manually annotated by BRENDA team
Zhao, J.; Li, G.; Zhao, Z.; Wang, J.; Gao, G.; He, S.
Matrix metalloproteinase-9 expression is increased in astrocytic glioma and associated with prognosis of patients
Jpn. J. Clin. Oncol.
42
1060-1065
2012
Homo sapiens (P14780), Homo sapiens
Manually annotated by BRENDA team
Francis, C.E.; Bai, Y.
Differential expression of cyclosporine A-Induced calcineurin isoform-specific matrix metalloproteinase 9 (MMP-9) in renal fibroblasts
Biochem. Biophys. Res. Commun.
503
2549-2554
2018
Mus musculus (P41245)
Manually annotated by BRENDA team
Lesniak-Walentyn, A.; Hrabia, A.
Expression and localization of matrix metalloproteinases (MMP-2, -7, -9) and their tissue inhibitors (TIMP-2, -3) in the chicken oviduct during maturation
Cell Tissue Res.
364
185-197
2016
Gallus gallus (Q9DE15), Gallus gallus, Gallus gallus Hy-Line Brown (Q9DE15)
Manually annotated by BRENDA team
Meffert, P.; Tscheuschler, A.; Beyersdorf, F.; Heilmann, C.; Kocher, N.; Uffelmann, X.; Discher, P.; Rylski, B.; Siepe, M.; Kari, F.A.
Characterization of serum matrix metalloproteinase 2/9 levels in patients with ascending aortic aneurysms
Interact. Cardiovasc. Thorac. Surg.
24
20-26
2017
Homo sapiens (P14780)
Manually annotated by BRENDA team
Ugarte-Berzal, E.; Vandooren, J.; Bailon, E.; Opdenakker, G.; Garcia-Pardo, A.
Inhibition of MMP-9-dependent degradation of gelatin, but not other MMP-9 substrates, by the MMP-9 hemopexin domain blades 1 and 4
J. Biol. Chem.
291
11751-11760
2016
Homo sapiens (P14780)
Manually annotated by BRENDA team
Baez, I.B.; Sampieri, C.L.; Solano, F.C.; Martinez Cazares, M.T.; Montero, H.; Cuevas, R.Z.
Activity of matrix metalloproteinase 2 and 9 isoforms in sputum samples from individuals infected with M. tuberculosis
Microb. Pathog.
135
103607
2019
Homo sapiens (P14780), Homo sapiens
Manually annotated by BRENDA team
Abu Bakar, A.R.; Ripen, A.M.; Merican, A.F.; Mohamad, S.B.
Enzymatic inhibitory activity of Ficus deltoidea leaf extract on matrix metalloproteinase-2, 8 and 9
Nat. Prod. Res.
33
1765-1768
2019
Homo sapiens (P14780)
Manually annotated by BRENDA team
Ugarte-Berzal, E.; Berghmans, N.; Boon, L.; Martens, E.; Vandooren, J.; Cauwe, B.; Thijs, G.; Proost, P.; Van Damme, J.; Opdenakker, G.
Gelatinase B/matrix metalloproteinase-9 is a phase-specific effector molecule, independent from Fas, in experimental autoimmune encephalomyelitis
PLoS ONE
13
e0197944
2018
Mus musculus (P41245)
Manually annotated by BRENDA team
Mohseni, S.; Moghadam, T.T.; Dabirmanesh, B.; Khajeh, K.
Expression, purification, refolding and invitro recovery of active full length recombinant human gelatinase MMP-9 in Escherichia coli
Protein Expr. Purif.
126
42-48
2016
Homo sapiens (P14780), Homo sapiens
Manually annotated by BRENDA team
Nicolai, E.; Sinibaldi, F.; Sannino, G.; Lagana, G.; Basoli, F.; Licoccia, S.; Cozza, P.; Santucci, R.; Piro, M.C.
Omega-3 and omega-6 fatty acids act as inhibitors of the matrix metalloproteinase-2 and matrix metalloproteinase-9 activity
Protein J.
36
278-285
2017
Homo sapiens (P14780)
Manually annotated by BRENDA team
Yuan, G.; Chen, L.; Feng, J.; Yang, G.; Ni, Q.; Xu, X.; Wan, C.; Lindsey, M.; Donly, K.J.; MacDougall, M.; Chen, Z.; Chen, S.
Dentin sialoprotein is a novel substrate of matrix metalloproteinase 9 in vitro and in vivo
Sci. Rep.
7
42449
2017
Mus musculus (P41245), Mus musculus
Manually annotated by BRENDA team