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Information on EC 3.4.22.B19 - YopJ protease

for references in articles please use BRENDA:EC3.4.22.B19
preliminary BRENDA-supplied EC number
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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.B19 YopJ protease
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Word Map
The enzyme appears in viruses and cellular organisms
Reaction Schemes
cleaves reversible post-translational modification in form of ubiquitin or a ubiquitin-like protein. It inhibits the host immune response and induces apoptosis by blocking multiple signaling pathways, including the MAPK and NfkappaB pathways in the infected cell
Synonyms
yersinia outer protein, virulence factor yopj, yersinia outer protein j, yersinia outer protein p, yersinia outer protein t, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
cleaves reversible post-translational modification in form of ubiquitin or a ubiquitin-like protein. It inhibits the host immune response and induces apoptosis by blocking multiple signaling pathways, including the MAPK and NfkappaB pathways in the infected cell
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