Reference on EC 3.4.22.62 - caspase-9
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REF. 
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Duan H.; Orth K.; Chinnaiyan A.M.; Poirier G.G.; Froelich C.J.; He W.W.; Dixit V.M.
ICE-LAP6, a novel member of the ICE/Ced-3 gene family, is activated by the cytotoxic T cell protease granzyme B
J. Biol. Chem.
271
16720-16724
1996
Homo sapiens (P55211)
Srinivasula, S.M.; Fernandes-Alnemri, T.; Zangrilli, J.; Robertson, N.; Armstrong, R.C.; Wang, L.; Trapani, J.A.; Tomaselli, K.J.; Litwack, G.; Alnemri E.S.
The Ced-3/interleukin 1beta converting enzyme-like homolog Mch6 and the lamin-cleaving enzyme Mch2alpha are substrates for the apoptotic mediator CPP32
J. Biol. Chem.
271
27099-27106
1996
Homo sapiens (P55211)
Seol, D.W.; Billiar, T.R.
A caspase-9 variant missing the catalytic site is an endogenous inhibitor of apoptosis
J. Biol. Chem.
274
2072-2076
1999
Homo sapiens (P55211), Homo sapiens
Allan, L.A.; Morrice, N.; Brady, S.; Magee, G.; Pathak, S.; Clarke, P.R.
Inhibition of caspase-9 through phosphorylation at Thr 125 by ERK MAPK
Nat. Cell Biol.
5
647-654
2003
Homo sapiens
Chou, K.C.; Tomasselli, A.G.; Heinrikson, R.L.
Prediction of the tertiary structure of a caspase-9/inhibitor complex
FEBS Lett.
470
249-256
2000
Homo sapiens
Rodriguez, J.; Lazebnik, Y.
Caspase-9 and APAF-1 form an active holoenzyme
Genes Dev.
13
3179-3184
1999
Homo sapiens
Zhivotovsky, B.; Samali, A.; Gahm, A.; Orrenius, S.
Caspases: their intracellular localization and translocation during apoptosis
Cell Death Differ.
6
644-651
1999
Homo sapiens
Pan, G.; O'Rourke, K.; Dixit, V.M.
Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex
J. Biol. Chem.
273
5841-5845
1998
Homo sapiens
Nakajima, K.; Takahashi, A.; Yaoita, Y.
Structure, expression, and function of the Xenopus laevis caspase family
J. Biol. Chem.
275
10484-10491
2000
Xenopus laevis
Garcia-Calvo, M.; Peterson, E.P.; Leiting, B.; Ruel, R.; Nicholson, D.W.; Thornberry, N.A.
Inhibition of human caspases by peptide-based and macromolecular inhibitors
J. Biol. Chem.
273
32608-32613
1998
Homo sapiens
Garcia-Calvo, M.; Peterson, E.P.; Rasper, D.M.; Vaillancourt, J.P.; Zamboni, R.; Nicholson, D.W.; Thornberry, N.A.
Purification and catalytic properties of human caspase family members
Cell Death Differ.
6
362-369
1999
Homo sapiens
Li, P.; Nijhawan, D.; Budihardjo, I.; Srinivasula, S.M.; Ahman, M.; Alnemric, E.S.; Wang, X.
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
Cell
91
479-489
1997
Homo sapiens
Srinivasula, S.M.; Ahmad, M.; Fernandes-Alnemric, T.; Alnemri, E.S.
Autoactivation of procaspase-9 by Apaf-1-mediated oligomerization
Mol. Cell
1
949-957
1998
Homo sapiens
Cardone, M.H.; Roy, N.; Stennicke, H.R.; Salvesen, G.S.; Franke, T.F.; Stanbridge, E.; Frisch, S.; Reed, J.C.
Regulation of cell death protease caspase-9 by phosphorylation
Science
282
1318-1321
1998
Homo sapiens
Chang, H.Y.; Yang, X.
Proteases from cell suicide: functions and regulation of caspases
Microbiol. Mol. Biol. Rev.
64
821-846
2000
Homo sapiens
Thornberry, N.A.; Rano, T.A.; Peterson, E.P.; et al.
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
J. Biol. Chem.
272
17907-17911
1997
Homo sapiens
Soung, Y.H.; Lee, J.W.; Kim, S.Y.; Park, W.S.; Nam, S.W.; Lee, J.Y.; Yoo, N.J.; Lee, S.H.
Mutational analysis of proapoptotic caspase-9 gene in common human carcinomas
APMIS
114
292-297
2006
Homo sapiens
Johnson, C.R.; Jarvis, W.D.
Caspase-9 regulation: an update
Apoptosis
9
423-427
2004
Homo sapiens
Takayama, E.; Higo, T.; Kai, M.; Fukasawa, M.; Nakajima, K.; Hara, H.; Tadakuma, T.; Igarashi, K.; Yaoita, Y.; Shiokawa, K.
Involvement of caspase-9 in execution of the maternal program of apoptosis in Xenopus late blastulae overexpressed with S-adenosylmethionine decarboxylase
Biochem. Biophys. Res. Commun.
325
1367-1375
2004
Xenopus laevis
Marsden, V.S.; Kaufmann, T.; Oreilly, L.A.; Adams, J.M.; Strasser, A.
Apaf-1 and caspase-9 are required for cytokine withdrawal-induced apoptosis of mast cells but dispensable for their functional and clonogenic death
Blood
107
1872-1877
2006
Mus musculus
Lin, L.; Zakeri, Z.
p53, Apaf-1, caspase-3, and -9 are dispensable for Cdk5 activation during cell death
Cell Death Differ.
13
141-150
2006
Mus musculus
Schamberger, C.J.; Gerner, C.; Cerni, C.
Caspase-9 plays a marginal role in serum starvation-induced apoptosis
Exp. Cell Res.
302
115-128
2005
Rattus norvegicus
Cheung, H.H.; Lynn Kelly, N.; Liston, P.; Korneluk, R.G.
Involvement of caspase-2 and caspase-9 in endoplasmic reticulum stress-induced apoptosis: a role for the IAPs
Exp. Cell Res.
312
2347-2357
2006
Homo sapiens
Martelli, A.M.; Cappellini, A.; Tazzari, P.L.; Billi, A.M.; Tassi, C.; Ricci, F.; Fala, F.; Conte, R.
Caspase-9 is the upstream caspase activated by 8-methoxypsoralen and ultraviolet-A radiation treatment of Jurkat T leukemia cells and normal T lymphocytes
Haematologica
89
471-479
2004
Homo sapiens
Kasili, P.M.; Song, J.M.; Vo-Dinh, T.
Optical sensor for the detection of caspase-9 activity in a single cell
J. Am. Chem. Soc.
126
2799-2806
2004
Homo sapiens
Akasaki, Y.; Liu, G.; Matunda, H.H.; Ng, H.; Yuan, X.; Zeng, Z.; Black, K.L.; Yu, J.S.
A peroxisome proliferator-activated receptor-gamma agonist, troglitazone, facilitates caspase-8 and -9 activities by increasing the enzymatic activity of protein-tyrosine phosphatase-1B on human glioma cells
J. Biol. Chem.
281
6165-6174
2006
Homo sapiens
Peluffo, M.C.; Young, K.A.; Stouffer, R.L.
Dynamic expression of caspase-2, -3, -8, and -9 proteins and enzyme activity, but not messenger ribonucleic acid, in the monkey corpus luteum during the menstrual cycle
J. Clin. Endocrinol. Metab.
90
2327-2335
2006
Macaca mulatta
Oberholzer, C.; Tschoeke, S.K.; Moldawer, L.L.; Oberholzer, A.
Local thymic caspase-9 inhibition improves survival during polymicrobial sepsis in mice
J. Mol. Med.
84
389-395
2006
Mus musculus
Wang, P.; Shi, T.; Ma, D.
Cloning of a novel human caspase-9 splice variant containing only the CARD domain
Life Sci.
79
934-940
2006
Homo sapiens (P55211), Homo sapiens
Imao, M.; Nagaki, M.; Imose, M.; Moriwaki, H.
Differential caspase-9-dependent signaling pathway between tumor necrosis factor receptor- and Fas-mediated hepatocyte apoptosis in mice
Liver Int.
26
137-146
2006
Mus musculus
Maglione, V.; Cannella, M.; Gradini, R.; Cislaghi, G.; Squitieri, F.
Huntingtin fragmentation and increased caspase 3, 8, and 9 activities in lymphoblasts with heterozygous and homozygous Huntington's disease mutation
Mech. Ageing Dev.
127
213-216
2006
Homo sapiens
Yin, Q.; Park, H.H.; Chung, J.Y.; Lin, S.C.; Lo, Y.C.; da Graca, L.S.; Jiang, X.; Wu, H.
Caspase-9 holoenzyme is a specific and optimal procaspase-3 processing machine
Mol. Cell
22
259-268
2006
Homo sapiens (P55211)
Pop, C.; Timmer, J.; Sperandio, S.; Salvesen, G.S.
The apoptosome activates caspase-9 by dimerization
Mol. Cell
22
269-275
2006
Homo sapiens
Yi, X.; Wang, J.; Seol, D.W.; Dong, Z.
Characterization of cell clones stably transfected with short form caspase-9: apoptotic resistance and Bcl-XL expression
Mol. Cell. Biochem.
282
1-12
2006
Rattus norvegicus
Mishra, O.P.; Delivoria-Papadopoulos, M.
ATP and cytochrome c-dependent inhibition of caspase-9 activity in the cerebral cortex of newborn piglets
Neurosci. Lett.
364
119-123
2004
Sus scrofa
Mishra, O.P.; Delivoria-Papadopoulos, M.
Effect of neuronal nitric oxide synthase inhibition on caspase-9 activity during hypoxia in the cerebral cortex of newborn piglets
Neurosci. Lett.
401
81-85
2006
Sus scrofa
Lemaire, C.; Godefroy, N.; Costina-Parvu, I.; Rincheval, V.; Renaud, F.; Trotot, P.; Bouleau, S.; Mignotte, B.; Vayssiere, J.L.
Caspase-9 can antagonize p53-induced apoptosis by generating a p76(Rb) truncated form of Rb
Oncogene
24
3297-3308
2005
Rattus norvegicus
Cepero, E.; King, A.M.; Coffey, L.M.; Perez, R.G.; Boise, L.H.
Caspase-9 and effector caspases have sequential and distinct effects on mitochondria
Oncogene
24
6354-6366
2005
Mus musculus
Sadhukhan, R.; Leone, J.W.; Lull, J.; Wang, Z.; Kletzien, R.F.; Heinrikson, R.L.; Tomasselli, A.G.
An efficient method to express and refold a truncated human procaspase-9: a caspase with activity toward Glu-X bonds
Protein Expr. Purif.
46
299-308
2006
Homo sapiens
Peluffo, M.C.; Bussmann, L.; Stouffer, R.L.; Tesone, M.
Expression of caspase-2, -3, -8 and -9 proteins and enzyme activity in the corpus luteum of the rat at different stages during the natural estrous cycle
Reproduction
132
465-475
2006
Rattus norvegicus
Papandile, A.; Tyas, D.; OMalley, D.M.; Warner, C.M.
Analysis of caspase-3, caspase-8 and caspase-9 enzymatic activities in mouse oocytes and zygotes
Zygote
12
57-64
2004
Mus musculus
Lysiak, J.J.; Zheng, S.; Woodson, R.; Turner, T.T.
Caspase-9-dependent pathway to murine germ cell apoptosis: mediation by oxidative stress, BAX, and caspase 2
Cell Tissue Res.
328
411-419
2007
Mus musculus
Saikumar, P.; Mikhailova, M.; Pandeswara, S.L.
Regulation of caspase-9 activity by differential binding to the apoptosome complex
Front. Biosci.
12
3343-3354
2007
Rattus norvegicus
Uchiyama, R.; Kawamura, I.; Fujimura, T.; Kawanishi, M.; Tsuchiya, K.; Tominaga, T.; Kaku, T.; Fukasawa, Y.; Sakai, S.; Nomura, T.; Mitsuyama, M.
Involvement of caspase-9 in the inhibition of necrosis of RAW 264 cells infected with Mycobacterium tuberculosis
Infect. Immun.
75
2894-2902
2007
Mus musculus
Samraj, A.K.; Keil, E.; Ueffing, N.; Schulze-Osthoff, K.; Schmitz, I.
Loss of caspase-9 provides genetic evidence for the type I/II concept of CD95-mediated apoptosis
J. Biol. Chem.
281
29652-29659
2006
Homo sapiens
Furuta, K.; Nakayama, K.; Sugimoto, Y.; Ichikawa, A.; Tanaka, S.
Activation of histidine decarboxylase through post-translational cleavage by caspase-9 in a mouse mastocytoma P-815
J. Biol. Chem.
282
13438-13446
2007
Mus musculus
Chen, M.; Guerrero, A.D.; Huang, L.; Shabier, Z.; Pan, M.; Tan, T.H.; Wang, J.
Caspase-9-induced mitochondrial disruption through cleavage of anti-apoptotic BCL-2 family members
J. Biol. Chem.
282
33888-33895
2007
Homo sapiens
Martin, M.C.; Allan, L.A.; Mancini, E.J.; Clarke, P.R.
The docking interaction of caspase-9 with ERK2 provides a mechanism for the selective inhibitory phosphorylation of caspase-9 at threonine 125
J. Biol. Chem.
283
3854-3865
2008
Homo sapiens
Yun, C.Y.; Liu, S.; Lim, S.F.; Wang, T.; Chung, B.Y.; Jiat Teo, J.; Chuan, K.H.; Soon, A.S.; Goh, K.S.; Song, Z.
Specific inhibition of caspase-8 and -9 in CHO cells enhances cell viability in batch and fed-batch cultures
Metab. Eng.
9
406-418
2007
Cricetulus griseus
Samraj, A.K.; Sohn, D.; Schulze-Osthoff, K.; Schmitz, I.
Loss of caspase-9 reveals its essential role for caspase-2 activation and mitochondrial membrane depolarization
Mol. Biol. Cell
18
84-93
2007
Homo sapiens
Allan, L.A.; Clarke, P.R.
Phosphorylation of caspase-9 by CDK1/cyclin B1 protects mitotic cells against apoptosis
Mol. Cell
26
301-310
2007
Homo sapiens
Gyrd-Hansen, M.; Farkas, T.; Fehrenbacher, N.; Bastholm, L.; Hoyer-Hansen, M.; Elling, F.; Wallach, D.; Flavell, R.; Kroemer, G.; Nylandsted, J.; Jaeaettelae, M.
Apoptosome-independent activation of the lysosomal cell death pathway by caspase-9
Mol. Cell. Biol.
26
7880-7891
2006
Mus musculus
Coen, L.; Le Blay, K.; Rowe, I.; Demeneix, B.A.
Caspase-9 regulates apoptosis/proliferation balance during metamorphic brain remodeling in Xenopus
Proc. Natl. Acad. Sci. USA
104
8502-8507
2007
Xenopus laevis
Loureiro, B.; Brad, A.M.; Hansen, P.J.
Heat shock and tumor necrosis factor-alpha induce apoptosis in bovine preimplantation embryos through a caspase-9-dependent mechanism
Reproduction
133
1129-1137
2007
Bos taurus
Kuckleburg, C.J.; Tiwari, R.; Czuprynski, C.J.
Endothelial cell apoptosis induced by bacteria-activated platelets requires caspase-8 and -9 and generation of reactive oxygen species
Thromb. Haemost.
99
363-372
2008
Bos taurus
Eeva, J.; Nuutinen, U.; Ropponen, A.; Maettoe, M.; Eray, M.; Pellinen, R.; Wahlfors, J.; Pelkonen, J.
The involvement of mitochondria and the caspase-9 activation pathway in rituximab-induced apoptosis in FL cells
Apoptosis
14
687-698
2009
Homo sapiens (P55211)
Yan, X.; Feng, C.; Chen, Q.; Li, W.; Wang, H.; Lv, L.; Smith, G.W.; Wang, J.
Effects of sodium fluoride treatment in vitro on cell proliferation, apoptosis and caspase-3 and caspase-9 mRNA expression by neonatal rat osteoblasts
Arch. Toxicol.
83
451-458
2008
Rattus norvegicus
Yi, J.Y.; Hirabayashi, Y.; Choi, Y.K.; Kodama, Y.; Kanno, J.; Han, J.H.; Inoue, T.; Yoon, B.I.
Benzene activates caspase-4 and -12 at the transcription level, without an association with apoptosis, in mouse bone marrow cells lacking the p53 gene
Arch. Toxicol.
83
795-803
2009
Mus musculus
Day, T.W.; Huang, S.; Safa, A.R.
c-FLIP knockdown induces ligand-independent DR5-, FADD-, caspase-8-, and caspase-9-dependent apoptosis in breast cancer cells
Biochem. Pharmacol.
76
1694-1704
2008
Homo sapiens (P55211)
Kim, S.J.; Shin, B.G.; Choi, I.Y.; Kim, D.H.; Kim, M.C.; Myung, N.Y.; Moon, P.D.; Lee, J.H.; An, H.J.; Kim, N.H.; Lee, J.Y.; So, H.S.; Park, R.K.; Jeong, H.J.; Um, J.Y.; Kim, H.M.; Hong, S.H.
Hwanggunchungyitang prevents cadmium-induced ototoxicity through suppression of the activation of caspase-9 and extracellular signal-related kinase in auditory HEI-OC1 cells
Biol. Pharm. Bull.
32
213-219
2009
Mus musculus (Q9R0T0)
Lee, H.J.; Lee, H.J.; Lee, E.O.; Ko, S.G.; Bae, H.S.; Kim, C.H.; Ahn, K.S.; Lu, J.; Kim, S.H.
Mitochondria-cytochrome C-caspase-9 cascade mediates isorhamnetin-induced apoptosis
Cancer Lett.
270
342-353
2008
Mus musculus (Q9R0T0)
Yamakawa, N.; Takahashi, A.; Mori, E.; Imai, Y.; Furusawa, Y.; Ohnishi, K.; Kirita, T.; Ohnishi, T.
High LET radiation enhances apoptosis in mutated p53 cancer cells through Caspase-9 activation
Cancer Sci.
99
1455-1460
2008
Homo sapiens (P55211), Homo sapiens
Zuo, Y.; Xiang, B.; Yang, J.; Sun, X.; Wang, Y.; Cang, H.; Yi, J.
Oxidative modification of caspase-9 facilitates its activation via disulfide-mediated interaction with APAF-1
Cell Res.
19
449-457
2009
Homo sapiens (P55211)
Laguna, A.; Aranda, S.; Barallobre, M.J.; Barhoum, R.; Fernandez, E.; Fotaki, V.; Delabar, J.M.; de la Luna, S.; de la Villa, P.; Arbones, M.L.
The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development
Dev. Cell
15
841-853
2008
Mus musculus (Q9R0T0), Mus musculus
Arnault, E.; Tosca, L.; Courtot, A.M.; Doussau, M.; Pesty, A.; Finaz, C.; Allemand, I.; Lefevre, B.
Caspase-2(L), caspase-9, and caspase-3 during in vitro maturation and fragmentation of the mouse oocyte
Dev. Dyn.
237
3892-3903
2008
Mus musculus (Q9R0T0), Mus musculus
Jen, C.Y.; Lin, C.Y.; Leu, S.F.; Huang, B.M.
Cordycepin induced MA-10 mouse Leydig tumor cell apoptosis through caspase-9 pathway
Evid. Based. Complement Alternat. Med.
2009
1-10
2009
Mus musculus (Q9R0T0), Mus musculus
Seifert, A.; Allan, L.A.; Clarke, P.R.
DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine
FEBS J.
275
6268-6280
2008
Homo sapiens (P55211), Homo sapiens
Yiang, G.T.; Yu, Y.L.; Hu, S.C.; Chen, M.H.; Wang, J.J.; Wei, C.W.
PKC and MEK pathways inhibit caspase-9/-3-mediated cytotoxicity in differentiated cells
FEBS Lett.
582
881-885
2008
Homo sapiens (P55211)
Tichy, A.; Zaskodova, D.; Pejchal, J.; Rezacova, M.; Osterreicher, J.; Vavrova, J.; Cerman, J.
Gamma irradiation of human leukaemic cells HL-60 and MOLT-4 induces decrease in Mcl-1 and Bid, release of cytochrome c, and activation of caspase-8 and caspase-9
Int. J. Radiat. Biol.
84
523-530
2008
Homo sapiens (P55211), Homo sapiens
Conte da Frota, M.L.; Braganhol, E.; Delgado Canedo, A.; Klamt, F.; Apel, M.A.; Mothes, B.; Lerner, C.; Oliveira Battastini, A.M.; Henriques, A.T.; Fonseca Moreira, J.C.
Extracts of marine sponge Polymastia janeirensis induce oxidative cell death through a caspase-9 apoptotic pathway in human U138MG glioma cell line
Invest. New Drugs
27
440-446
2008
Homo sapiens (P55211), Homo sapiens
McDonnell, M.A.; Abedin, M.J.; Melendez, M.; Platikanova, T.N.; Ecklund, J.R.; Ahmed, K.; Kelekar, A.
Phosphorylation of murine caspase-9 by the protein kinase casein kinase 2 regulates its cleavage by caspase-8
J. Biol. Chem.
283
20149-20158
2008
Mus musculus (Q9R0T0), Mus musculus
Murray, T.V.; McMahon, J.M.; Howley, B.A.; Stanley, A.; Ritter, T.; Mohr, A.; Zwacka, R.; Fearnhead, H.O.
A non-apoptotic role for caspase-9 in muscle differentiation
J. Cell Sci.
121
3786-3793
2008
Mus musculus (Q9R0T0)
Yasuda, Y.; Saito, M.; Yamamura, T.; Yaguchi, T.; Nishizaki, T.
Extracellular adenosine induces apoptosis in Caco-2 human colonic cancer cells by activating caspase-9/-3 via A(2a) adenosine receptors
J. Gastroenterol.
44
56-65
2009
Homo sapiens (P55211), Homo sapiens
de Witte, M.A.; Jorritsma, A.; Swart, E.; Straathof, K.C.; de Punder, K.; Haanen, J.B.; Rooney, C.M.; Schumacher, T.N.
An inducible caspase 9 safety switch can halt cell therapy-induced autoimmune disease
J. Immunol.
180
6365-6373
2008
Mus musculus (Q9R0T0), Mus musculus
Mondragon, L.; Orzaez, M.; Sanclimens, G.; Moure, A.; Arminan, A.; Sepulveda, P.; Messeguer, A.; Vicent, M.J.; Perez-Paya, E.
Modulation of cellular apoptosis with apoptotic protease-activating factor 1 (Apaf-1) inhibitors
J. Med. Chem.
51
521-529
2008
Rattus norvegicus, Homo sapiens (P55211)
Andreoli, V.; Trecroci, F.; La Russa, A.; Valentino, P.; Condino, F.; Latorre, V.; Nistico, R.; Pirritano, D.; Del Giudice, F.; Canino, M.; Cittadella, R.; Quattrone, A.
CASP-9: A susceptibility locus for multiple sclerosis in Italy
J. Neuroimmunol.
210
100-103
2009
Homo sapiens (P55211), Homo sapiens
Checinska, A.; Giaccone, G.; Rodriguez, J.A.; Kruyt, F.A.; Jimenez, C.R.
Comparative proteomics analysis of caspase-9-protein complexes in untreated and cytochrome c/dATP stimulated lysates of NSCLC cells
J. Proteomics
72
575-585
2009
Homo sapiens (P55211)
Aprigliano, I.; Dudas, J.; Ramadori, G.; Saile, B.
Atorvastatin induces apoptosis by a caspase-9-dependent pathway: an in vitro study on activated rat hepatic stellate cells
Liver Int.
28
546-557
2008
Rattus norvegicus, Rattus norvegicus Wistar
Zhao, J.F.; Sun, A.H.; Ruan, P.; Zhao, X.H.; Lu, M.Q.; Yan, J.
Vibrio vulnificus cytolysin induces apoptosis in HUVEC, SGC-7901 and SMMC-7721 cells via caspase-9/3-dependent pathway
Microb. Pathog.
46
194-200
2009
Homo sapiens (P55211), Homo sapiens
Mukherjee, J.J.; Gupta, S.K.; Kumar, S.
Inhibition of benzopyrene-diol-epoxide (BPDE)-induced bax and caspase-9 by cadmium: role of mitogen activated protein kinase
Mutat. Res.
661
41-46
2009
Homo sapiens (P55211), Homo sapiens
Levenbrown, Y.; Ashraf, Q.M.; Maounis, N.; Mishra, O.P.; Delivoria-Papadopoulos, M.
Phosphorylation of caspase-9 in the cytosolic fraction of the cerebral cortex of newborn piglets following hypoxia
Neurosci. Lett.
447
96-99
2008
Sus scrofa
Darwish, R.S.; Amiridze, N.S.
Detectable levels of cytochrome C and activated caspase-9 in cerebrospinal fluid after human traumatic brain injury
Neurocrit. Care
12
337-341
2010
Homo sapiens
Jeong, H.S.; Choi, H.Y.; Lee, E.R.; Kim, J.H.; Jeon, K.; Lee, H.J.; Cho, S.G.
Involvement of caspase-9 in autophagy-mediated cell survival pathway
Biochim. Biophys. Acta
1813
80-90
2011
Homo sapiens
Abou-Kandil, A.; Chamias, R.; Huleihel, M.; Godbey, W.T.; Aboud, M.
Role of caspase 9 in activation of HTLV-1 LTR expression by DNA damaging agents
Cell Cycle
10
3337-3345
2011
Homo sapiens
Wu, Y.; Wang, D.; Wang, X.; Wang, Y.; Ren, F.; Chang, D.; Chang, Z.; Jia, B.
Caspase 3 is activated through caspase 8 instead of caspase 9 during H2O2-induced apoptosis in HeLa cells
Cell. Physiol. Biochem.
27
539-546
2011
Homo sapiens
Mu, Y.; Xiao, X.; Zhang, J.; Ao, J.; Chen, X.
Molecular cloning and functional characterization of caspase 9 in large yellow croaker (Pseudosciaena crocea)
Dev. Comp. Immunol.
34
300-307
2010
Larimichthys crocea
Li, T.; Cui, Z.B.; Ke, X.X.; Tan, J.; Li, F.F.; Li, T.; Wang, X.W.; Cui, H.J.
Essential role for p53 and caspase-9 in DNA damaging drug-induced apoptosis in neuroblastoma IMR32 cells
DNA Cell Biol.
30
1045-1050
2011
Homo sapiens
Du, R.H.; Cui, J.T.; Wang, T.; Zhang, A.H.; Tan, R.X.
Trichothecin induces apoptosis of HepG2 cells via caspase-9 mediated activation of the mitochondrial death pathway
Toxicon
59
143-150
2012
Homo sapiens
Gao, D.; Xu, Z.; Zhang, X.; Wang, H.; Wang, Y.; Min, W.
Molecular cloning, immunohistochemical localization, characterization and expression analysis of caspase-9 from the purse red common carp (Cyprinus carpio) exposed to cadmium
Aquat. Toxicol.
142-143
53-62
2013
Cyprinus carpio
Bourguet, C.B.; Boulay, P.L.; Claing, A.; Lubell, W.D.
Design and synthesis of novel azapeptide activators of apoptosis mediated by caspase-9 in cancer cells
Bioorg. Med. Chem. Lett.
24
3361-3365
2014
Homo sapiens
Huber, K.L.; Ghosh, S.; Hardy, J.A.
Inhibition of caspase-9 by stabilized peptides targeting the dimerization interface
Biopolymers
98
451-465
2012
Homo sapiens
Lu, E.P.; McLellan, M.; Ding, L.; Fulton, R.; Mardis, E.R.; Wilson, R.K.; Miller, C.A.; Westervelt, P.; DiPersio, J.F.; Link, D.C.; Walter, M.J.; Ley, T.J.; Graubert, T.A.
Caspase-9 is required for normal hematopoietic development and protection from alkylator-induced DNA damage in mice
Blood
124
3887-3895
2014
Mus musculus, Mus musculus C57/BL6J
Brentnall, M.; Rodriguez-Menocal, L.; De Guevara, R.L.; Cepero, E.; Boise, L.H.
Caspase-9, caspase-3 and caspase-7 have distinct roles during intrinsic apoptosis
BMC Cell Biol.
14
32
2013
Mus musculus
Nie, C.; Luo, Y.; Zhao, X.; Luo, N.; Tong, A.; Liu, X.; Yuan, Z.; Wang, C.; Wei, Y.
Caspase-9 mediates Puma activation in UCN-01-induced apoptosis
Cell Death Dis.
5
e1495
2014
Homo sapiens
Wuerstle, M.L.; Laussmann, M.A.; Rehm, M.
The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome
Exp. Cell Res.
318
1213-1220
2012
Homo sapiens
Blanch, R.J.; Ahmed, Z.; Thompson, A.R.; Akpan, N.; Snead, D.R.; Berry, M.; Troy, C.M.; Scott, R.A.; Logan, A.
Caspase-9 mediates photoreceptor death after blunt ocular trauma
Invest. Ophthalmol. Vis. Sci.
55
6350-6357
2014
Rattus norvegicus
Huber, K.L.; Hardy, J.A.
Mechanism of zinc-mediated inhibition of caspase-9
Protein Sci.
21
1056-1065
2012
Homo sapiens
Wei, X.; Li, Q.; Han, Z.; Lin, D.; Yu, P.
Differences in caspase-8 and -9 activity and sperm motility in infertile males of Li nationality in China
Int. J. Clin. Exp. Med.
8
4721-4726
2015
Homo sapiens (P55211), Homo sapiens
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