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Information on EC 3.4.22.36 - caspase-1

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EC Tree
     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.22 Cysteine endopeptidases
                3.4.22.36 caspase-1
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Word Map
  • 3.4.22.36
  • inflammasome
  • caspases
  • pyroptosis
  • pyrin
  • nod-like
  • lipopolysaccharide
  • apoptosis-associated
  • speck-like
  • toll-like
  • card
  • multiprotein
  • nucleotide-binding
  • adaptor
  • pro-il-1
  • danger
  • microglia
  • neuroinflammation
  • leucine-rich
  • tunel
  • domain-containing
  • marrow-derived
  • domain-like
  • interleukin-18
  • autoinflammatory
  • lps-induced
  • flice
  • urate
  • flagellin
  • txnip
  • z-vad-fmk
  • damage-associated
  • anti-fas
  • medicine
  • il-1ra
  • pan-caspase
  • caspase-3-like
  • gout
  • executioner
  • polyadp-ribose
  • lymphopoietin
  • francisella
  • fas-associated
  • prodomains
  • monosodium
  • pathogen-associated
  • nigericin
  • ac-devd-cho
  • disintegrin
  • caspase-activating
  • z-devd-fmk
  • fas-mediated
The enzyme appears in viruses and cellular organisms
Reaction Schemes
Strict requirement for an Asp residue at position P1 and has a preferred cleavage sequence of Tyr-Val-Ala-Asp-/-
Synonyms
caspase 1, effector caspase, casp1, procaspase-1, interleukin-1beta-converting enzyme, interleukin-1 beta converting enzyme, interleukin-1beta converting enzyme, il-1beta-converting enzyme, csp-1, casp-1, more
REACTION
REACTION DIAGRAM
COMMENTARY hide
ORGANISM
UNIPROT
LITERATURE
Strict requirement for an Asp residue at position P1 and has a preferred cleavage sequence of Tyr-Val-Ala-Asp-/-
show the reaction diagram
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