Reference on EC 3.4.22.30 - Caricain
Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Polgar, L.
Isolation of highly active papaya peptidases A and B from commercial chymopapain
Biochim. Biophys. Acta
658
262-269
1981
Carica papaya
Sumner, I.G.; Harris, G.W.; Taylor, M.A.J.; Pickersgill, R.W.; Owen, A.J.; Goodenough, P.W.
Factors effecting the thermostability of cysteine proteinases from Carica papaya
Eur. J. Biochem.
214
129-134
1993
Carica papaya
Goodenough, P.E.; Owen, J.
Chromatographic and electrophoretic analyses of papaya proteinases
Phytochemistry
26
75-79
1987
Carica papaya
-
Brocklehurst, K.; Baines, B.S.; Salih, E.; Hatzoulis, C.
Chymopapain S is chymopapain A
Biochem. J.
221
553-554
1984
Carica papaya
Polgar, L.
Problems of classification of papaya latex proteinases
Biochem. J.
221
555-556
1984
Carica papaya
Brocklehurst, K.; Salih, E.; McKee, R.; Smith, H.
Fresh non-fruit latex of Carica papaya contains papain, multiple forms of chymopapain A and papaya proteinase omega
Biochem. J.
228
525-527
1985
Carica papaya
Barrett, A.J.; Buttle, D.J.
Names and numbers of papaya proteinases
Biochem. J.
228
527
1985
Carica papaya
Dubois, T.; Kleinschmidt, T.; Schnek, A.G.; Looze, Y.; Braunitzer, G.
The thiol proteinases from the latex of Carica papaya L. II. The primary structure of proteinase omega
Biol. Chem. Hoppe-Seyler
369
741-754
1988
Carica papaya
Zucker, S.; Buttle, D.J.; Nicklin, M.J.H.; Barrett, A.J.
The proteolytic activities of chymopapain, papain, and papaya proteinase III
Biochim. Biophys. Acta
828
196-204
1985
Carica papaya
Baines, B.S.; Brocklehurst, K.
Characterization of papaya peptidase A as a cysteine proteinase of Carica papaya L. with active-centre properties that differ from those of papain by using 2,2-dipyridyl disulphide and 4-chloro-7-nitrobenzofurazan as reactivity probes. Use of two-protonic-state electrophiles in the identification of catalytic-site thiol groups
Biochem. J.
205
205-211
1982
Carica papaya
Robinson, G.W.
Isolation and characterization of papaya peptidase A from commercial chymopapain
Biochemistry
14
3695-3700
1975
Carica papaya
Goodenough, P.W.; Owen, J.
Papaya proteinases separated by novel means have been used to generate monoclonal antibodies
Biochem. Soc. Trans.
15
264-265
1987
Carica papaya
-
Baines, B.S.; Brocklehurst, K.; Carey, P.R.; Jarvis, M.; Salih, E.; Storer, A.C.
Chymopapain A. Purification and investigation by covalent chromatography and characterization by two-protonic-state reactivity-probe kinetics, steady-state kinetics and resonance Raman spectroscopy of some dithioacyl derivatives
Biochem. J.
233
119-129
1986
Carica papaya
Schack, P.; Kaarsholm, N.C.
Absence in papaya peptidase A catalyzed hydrolyses of a pKa apprx. 4 present in papain-catalyzed hydrolyses
Biochemistry
23
631-635
1984
Carica papaya
-
Schack, P.; Kaarsholm, N.C.
Subsite differences between the active centres of papaya peptidase A and papain as revealed by affinity chromatography. Purification of papaya peptidase A by ionic-strength-dependent affinity adsorption on an immobilized peptide inhibitor of papain
Biochem. J.
219
727-733
1984
Carica papaya
Sumner, I.G.; Vaughan, A.; Eisenthal, R.; Pickersgill, R.W.; Owen, A.J.; Goodenough, P.W.
Kinetic analysis of papaya proteinase omega
Biochim. Biophys. Acta
1164
243-251
1993
Carica papaya
Topham, C.M.; Salih, E.; Frazao, C.; Kowlessur, D.; Overington, J.P.; Thomas, M.; Brocklehurst, S.M.; Patel, M.; Thomas, E.W.; Brocklehurst, K.
Structure-function relationships in the cysteine proteinases actinidin, papain and papaya proteinase omega. Three-dimensional structure of papaya proteinase omega deduced by knowledge-based modelling and active-centre characteristics determined by two-hydronic-state reactivity probe kinetics and kinetics of catalysis
Biochem. J.
280
79-92
1991
Carica papaya
Kaarsholm, N.C.; Schack, P.
Characterization of papaya peptidase A as an enzyme of extreme basicity
Acta Chem. Scand. B
37
607-611
1983
Carica papaya
Noble, M.A.; Gul, S.; Verma, C.S.; Brocklehurst, K.
Ionization characteristics and chemical influences of aspartic acid residue 158 of papain and caricain determined by structure-related kinetic and computational techniques: multiple electrostatic modulators of active-centre chemistry
Biochem. J.
351
723-733
2000
Carica papaya
Reid, J.D.; Hussain, S.; Sreedharan, S.K.; Bailey, T.S.F.; Pinitglang, S.; Thomas, E.W.; Verma, C.S.; Brocklehurst, K.
Variation in aspects of cysteine proteinase catalytic mechanism deduced by spectroscopic observation of dithioester intermediates, kinetic analysis and molecular dynamics simulations
Biochem. J.
357
343-352
2001
Carica papaya
Pinitglang, S.; Patel, M.; Noble, M.; Sreedharan, S.K.; Verma, C.; Thomas, E.W.; Brocklehurst, K.
Effects of the quality of the P2-S2 hydrophobic contacts on the catalytic activities of papain, caricain and ficin and their generation by electrostatic switches
Biochem. Soc. Trans.
25
88S
1997
Carica papaya
Noble, M.; Abramson, D.; Verma, C.; Brocklehurst, K.
Evidence that the carboxy groups of Asp158 in papain and caricain have abnormally low pKa values and thus do not contribute the key ionizations with pKa 4 that generate catalytic competence
Biochem. Soc. Trans.
25
90S
1997
Carica papaya
Khan, A.; Connerton, I.F.; Cummings, N.J.; Hussain, S.; Noble, M.A.; Taylor, M.A.J.; Thomas, E.W.; Verma, C.; Brocklehurst, K.
The kinetically influential ionizations of caricain D158N revealed by using 4,4'-dipyrimidyl disulfide as a reactivity probe
Biochem. Soc. Trans.
26
S172
1998
Carica papaya
Lopez-Arenas, L.; Solis-Mendiola, S.; Hernandez-Arana, A.
Estimating the degree of expansion in the transition state for protein unfolding: analysis of the pH dependence of the rate constant for caricain denaturation
Biochemistry
38
15936-15943
1999
Carica papaya
Ikeuchi, Y.; Katerelos, N.A.; Goodenough, P.W.
The enhancing of a cysteine proteinase activity at acidic pH by protein engineering, the role of glutamic 50 in the enzyme mechanism of caricain
FEBS Lett.
437
91-96
1998
Carica papaya (P10056), Carica papaya
Azarkan, M.; El Moussaoui, A.; van Wuytswinkel, D.; Dehon, G.; Looze, Y.
Fractionation and purification of the enzymes stored in the latex of Carica papaya
J. Chromatogr. B
790
229-238
2003
Carica papaya
Huet, J.; Looze, Y.; Bartik, K.; Raussens, V.; Wintjens, R.; Boussard, P.
Structural characterization of the papaya cysteine proteinases at low pH
Biochem. Biophys. Res. Commun.
341
620-626
2006
Carica papaya
Azarkan, M.; Dibiani, R.; Baulard, C.; Baeyens-Volant, D.
Effects of mechanical wounding on Carica papaya cysteine endopeptidases accumulation and activity
Int. J. Biol. Macromol.
38
216-224
2006
Carica papaya
Liu, W.; Ye, W.; Wang, Z.; Chao, H.; Lian, J.
Preparation and characterization of a truncated caricain lacking 41 residues from the N-terminal
Protein J.
24
243-251
2005
Carica papaya
Cornell, H.J.; Doherty, W.; Stelmasiak, T.
Papaya latex enzymes capable of detoxification of gliadin
Amino Acids
38
155-165
2009
Carica papaya, Carica papaya (P10056)
Cornell, H.; Stelmasiak, T.
Caricain: A basis for enzyme therapy for coeliac disease
South Afr. J. Sci.
107
75-79
2011
Carica papaya
-
Buddrick, O.; Cornell, H.J.; Small, D.M.
Reduction of toxic gliadin content of wholegrain bread by the enzyme caricain
Food Chem.
170
343-347
2015
Carica papaya (P10056), Carica papaya
html completed