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Disease on EC 3.4.21.B45 - kallikrein 14

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Adenocarcinoma
High expression of KLK14 in prostatic adenocarcinoma is associated with elevated risk of prostate-specific antigen relapse.
Adenoma
Parallel overexpression and clinical significance of kallikrein-related peptidases 7 and 14 (KLK7 KLK14) in colon cancer.
Adenoma, Pleomorphic
Human kallikrein 14 (KLK14) expression in salivary gland tumors.
Breast Neoplasms
Enzymatic profiling of human kallikrein 14 using phage-display substrate technology.
Expression and enzymatic characterization of recombinant human kallikrein 14.
Expression of human Kallikrein 14 (KLK14) in breast cancer is associated with higher tumour grades and positive nodal status.
Human kallikrein 14: a new potential biomarker for ovarian and breast cancer.
MSR1 repeats modulate gene expression and affect risk of breast and prostate cancer.
Quantitative analysis of human kallikrein gene 14 expression in breast tumours indicates association with poor prognosis.
Quantitative expression analysis and study of the novel human kallikrein-related peptidase 14 gene (KLK14) in malignant and benign breast tissues.
Significant alterations in the expression pattern of kallikrein-related peptidase genes KLK4, KLK5 and KLK14 after treatment of breast cancer cells with the chemotherapeutic agents epirubicin, docetaxel and methotrexate.
The canine kallikrein-related peptidase 14: structural characterization, alternative splicing and differential expression in mammary cancer.
Carcinogenesis
Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells.
Kallikrein-related peptidase signaling in colon carcinoma cells: Targeting proteinase-activated receptors (PARs).
Kallikrein-related peptidase signaling in colon carcinoma cells: targeting proteinase-activated receptors.
Parallel overexpression and clinical significance of kallikrein-related peptidases 7 and 14 (KLK7 KLK14) in colon cancer.
Carcinoma
Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
Effects of kallikrein-related peptidase 14 gene inhibition by small interfering RNA in ovarian carcinoma cells.
Human kallikrein 14 (KLK14) expression in salivary gland tumors.
Quantitative expression analysis and study of the novel human kallikrein-related peptidase 14 gene (KLK14) in malignant and benign breast tissues.
Carcinoma, Adenoid Cystic
Human kallikrein 14 (KLK14) expression in salivary gland tumors.
Carcinoma, Hepatocellular
Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
Carcinoma, Mucoepidermoid
Human kallikrein 14 (KLK14) expression in salivary gland tumors.
Carcinoma, Renal Cell
Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
Colonic Neoplasms
Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells.
Kallikrein-related peptidase 7 (KLK7) is a proliferative factor that is aberrantly expressed in human colon cancer.
Kallikrein-related peptidase signaling in colon carcinoma cells: Targeting proteinase-activated receptors (PARs).
Kallikrein-related peptidase signaling in colon carcinoma cells: targeting proteinase-activated receptors.
Dermatitis, Atopic
Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients.
Hereditary Complement Deficiency Diseases
Induction of complement c3a receptor responses by kallikrein-related peptidase 14.
Leukemia, Lymphocytic, Chronic, B-Cell
mRNA overexpression of kallikrein-related peptidase 14 (KLK14) is an independent predictor of poor overall survival in chronic lymphocytic leukemia patients.
Lung Neoplasms
Quantitative RT-PCR analysis and immunohistochemical localization of the kallikrein-related peptidases 13 and 14 in lung.
Neoplasm Metastasis
The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.
Neoplasm, Residual
Advanced high-grade serous ovarian cancer: inverse association of KLK13 and KLK14 mRNA levels in tumor tissue and patients' prognosis.
Neoplasms
A Suite of Activity-Based Probes To Dissect the KLK Activome in Drug-Resistant Prostate Cancer.
Advanced high-grade serous ovarian cancer: inverse association of KLK13 and KLK14 mRNA levels in tumor tissue and patients' prognosis.
Cloning of a new member of the human kallikrein gene family, KLK14, which is down-regulated in different malignancies.
Differential expression of the human kallikrein gene 14 (KLK14) in normal and cancerous prostatic tissues.
Effects of kallikrein-related peptidase 14 gene inhibition by small interfering RNA in ovarian carcinoma cells.
Enzymatic profiling of human kallikrein 14 using phage-display substrate technology.
Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14.
Expression of human Kallikrein 14 (KLK14) in breast cancer is associated with higher tumour grades and positive nodal status.
High expression of KLK14 in prostatic adenocarcinoma is associated with elevated risk of prostate-specific antigen relapse.
Human kallikrein 14 (KLK14) expression in salivary gland tumors.
Human kallikrein 14: a new potential biomarker for ovarian and breast cancer.
Human tissue kallikreins and testicular cancer.
In vitro evidence that KLK14 regulates the components of the HGF/Met axis, pro-HGF and HGF-activator inhibitor 1A and 1B.
Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells.
Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin.
Kallikrein-related peptidase signaling in colon carcinoma cells: targeting proteinase-activated receptors.
KLK14 interactions with HAI-1 and HAI-2 serine protease inhibitors: A molecular dynamics and relative free-energy calculations study.
Mutant recombinant serpins as highly specific inhibitors of human kallikrein 14.
Non-combinatorial library screening reveals subsite cooperativity and identifies new high efficiency substrates for kallikrein-related peptidase 14.
Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14.
Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases.
Quantitative analysis of human kallikrein gene 14 expression in breast tumours indicates association with poor prognosis.
Quantitative expression analysis and study of the novel human kallikrein-related peptidase 14 gene (KLK14) in malignant and benign breast tissues.
Quantitative RT-PCR analysis and immunohistochemical localization of the kallikrein-related peptidases 13 and 14 in lung.
Steroid hormone regulation and prognostic value of the human kallikrein gene 14 in ovarian cancer.
The kallikrein 14 gene is down-regulated by androgen receptor signalling and harbours genetic variation that is associated with prostate tumour aggressiveness.
The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.
Neoplasms, Germ Cell and Embryonal
Human tissue kallikreins and testicular cancer.
Netherton Syndrome
Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin.
Toward the first class of suicide inhibitors of kallikreins involved in skin diseases.
Ovarian Neoplasms
Advanced high-grade serous ovarian cancer: inverse association of KLK13 and KLK14 mRNA levels in tumor tissue and patients' prognosis.
Cloning of a new member of the human kallikrein gene family, KLK14, which is down-regulated in different malignancies.
Effects of kallikrein-related peptidase 14 gene inhibition by small interfering RNA in ovarian carcinoma cells.
Human kallikrein 14: a new potential biomarker for ovarian and breast cancer.
Quantitative analysis of human kallikrein gene 14 expression in breast tumours indicates association with poor prognosis.
Steroid hormone regulation and prognostic value of the human kallikrein gene 14 in ovarian cancer.
Prostatic Neoplasms
Differential expression of the human kallikrein gene 14 (KLK14) in normal and cancerous prostatic tissues.
Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14.
High expression of KLK14 in prostatic adenocarcinoma is associated with elevated risk of prostate-specific antigen relapse.
In vitro evidence that KLK14 regulates the components of the HGF/Met axis, pro-HGF and HGF-activator inhibitor 1A and 1B.
Kallikrein gene family as biomarkers for recurrent prostate cancer.
Kallikreins are involved in an miRNA network that contributes to prostate cancer progression.
KLK14 interactions with HAI-1 and HAI-2 serine protease inhibitors: A molecular dynamics and relative free-energy calculations study.
MSR1 repeats modulate gene expression and affect risk of breast and prostate cancer.
The kallikrein 14 gene is down-regulated by androgen receptor signalling and harbours genetic variation that is associated with prostate tumour aggressiveness.
The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.
Psoriasis
Aberrant human tissue kallikrein levels in the stratum corneum and serum of patients with psoriasis: dependence on phenotype, severity and therapy.
Skin Diseases
Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin.
Toward the first class of suicide inhibitors of kallikreins involved in skin diseases.
Transgenic kallikrein 14 mice display major hair shaft defects associated with desmoglein 3 and 4 degradation, abnormal epidermal differentiation and Il-36 signature.
Testicular Neoplasms
Human tissue kallikreins and testicular cancer.
Quantitative analysis of human kallikrein gene 14 expression in breast tumours indicates association with poor prognosis.