Disease on EC 3.4.21.B45 - kallikrein 14
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Adenocarcinoma
High expression of KLK14 in prostatic adenocarcinoma is associated with elevated risk of prostate-specific antigen relapse.
Adenoma
Parallel overexpression and clinical significance of kallikrein-related peptidases 7 and 14 (KLK7 KLK14) in colon cancer.
Breast Neoplasms
Enzymatic profiling of human kallikrein 14 using phage-display substrate technology.
Breast Neoplasms
Expression and enzymatic characterization of recombinant human kallikrein 14.
Breast Neoplasms
Expression of human Kallikrein 14 (KLK14) in breast cancer is associated with higher tumour grades and positive nodal status.
Breast Neoplasms
Human kallikrein 14: a new potential biomarker for ovarian and breast cancer.
Breast Neoplasms
MSR1 repeats modulate gene expression and affect risk of breast and prostate cancer.
Breast Neoplasms
Quantitative analysis of human kallikrein gene 14 expression in breast tumours indicates association with poor prognosis.
Breast Neoplasms
Quantitative expression analysis and study of the novel human kallikrein-related peptidase 14 gene (KLK14) in malignant and benign breast tissues.
Breast Neoplasms
Significant alterations in the expression pattern of kallikrein-related peptidase genes KLK4, KLK5 and KLK14 after treatment of breast cancer cells with the chemotherapeutic agents epirubicin, docetaxel and methotrexate.
Breast Neoplasms
The canine kallikrein-related peptidase 14: structural characterization, alternative splicing and differential expression in mammary cancer.
Carcinogenesis
Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells.
Carcinogenesis
Kallikrein-related peptidase signaling in colon carcinoma cells: Targeting proteinase-activated receptors (PARs).
Carcinogenesis
Kallikrein-related peptidase signaling in colon carcinoma cells: targeting proteinase-activated receptors.
Carcinogenesis
Parallel overexpression and clinical significance of kallikrein-related peptidases 7 and 14 (KLK7 KLK14) in colon cancer.
Carcinoma
Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
Carcinoma
Effects of kallikrein-related peptidase 14 gene inhibition by small interfering RNA in ovarian carcinoma cells.
Carcinoma
Quantitative expression analysis and study of the novel human kallikrein-related peptidase 14 gene (KLK14) in malignant and benign breast tissues.
Carcinoma, Hepatocellular
Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
Carcinoma, Renal Cell
Diagnostic and prognostic biomarker potential of kallikrein family genes in different cancer types.
Colonic Neoplasms
Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells.
Colonic Neoplasms
Kallikrein-related peptidase 7 (KLK7) is a proliferative factor that is aberrantly expressed in human colon cancer.
Colonic Neoplasms
Kallikrein-related peptidase signaling in colon carcinoma cells: Targeting proteinase-activated receptors (PARs).
Colonic Neoplasms
Kallikrein-related peptidase signaling in colon carcinoma cells: targeting proteinase-activated receptors.
Dermatitis, Atopic
Human tissue kallikrein expression in the stratum corneum and serum of atopic dermatitis patients.
Hereditary Complement Deficiency Diseases
Induction of complement c3a receptor responses by kallikrein-related peptidase 14.
Leukemia, Lymphocytic, Chronic, B-Cell
mRNA overexpression of kallikrein-related peptidase 14 (KLK14) is an independent predictor of poor overall survival in chronic lymphocytic leukemia patients.
Lung Neoplasms
Quantitative RT-PCR analysis and immunohistochemical localization of the kallikrein-related peptidases 13 and 14 in lung.
Neoplasm Metastasis
The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.
Neoplasm, Residual
Advanced high-grade serous ovarian cancer: inverse association of KLK13 and KLK14 mRNA levels in tumor tissue and patients' prognosis.
Neoplasms
A Suite of Activity-Based Probes To Dissect the KLK Activome in Drug-Resistant Prostate Cancer.
Neoplasms
Advanced high-grade serous ovarian cancer: inverse association of KLK13 and KLK14 mRNA levels in tumor tissue and patients' prognosis.
Neoplasms
Cloning of a new member of the human kallikrein gene family, KLK14, which is down-regulated in different malignancies.
Neoplasms
Differential expression of the human kallikrein gene 14 (KLK14) in normal and cancerous prostatic tissues.
Neoplasms
Effects of kallikrein-related peptidase 14 gene inhibition by small interfering RNA in ovarian carcinoma cells.
Neoplasms
Enzymatic profiling of human kallikrein 14 using phage-display substrate technology.
Neoplasms
Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14.
Neoplasms
Expression of human Kallikrein 14 (KLK14) in breast cancer is associated with higher tumour grades and positive nodal status.
Neoplasms
High expression of KLK14 in prostatic adenocarcinoma is associated with elevated risk of prostate-specific antigen relapse.
Neoplasms
In vitro evidence that KLK14 regulates the components of the HGF/Met axis, pro-HGF and HGF-activator inhibitor 1A and 1B.
Neoplasms
Kallikrein-related peptidase 14 acts on proteinase-activated receptor 2 to induce signaling pathway in colon cancer cells.
Neoplasms
Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin.
Neoplasms
Kallikrein-related peptidase signaling in colon carcinoma cells: targeting proteinase-activated receptors.
Neoplasms
KLK14 interactions with HAI-1 and HAI-2 serine protease inhibitors: A molecular dynamics and relative free-energy calculations study.
Neoplasms
Non-combinatorial library screening reveals subsite cooperativity and identifies new high efficiency substrates for kallikrein-related peptidase 14.
Neoplasms
Non-combinatorial library screening reveals subsite cooperativity and identifies new high-efficiency substrates for kallikrein-related peptidase 14.
Neoplasms
Pericellular regulation of prostate cancer expressed kallikrein-related peptidases and matrix metalloproteinases by cell surface serine proteases.
Neoplasms
Quantitative analysis of human kallikrein gene 14 expression in breast tumours indicates association with poor prognosis.
Neoplasms
Quantitative expression analysis and study of the novel human kallikrein-related peptidase 14 gene (KLK14) in malignant and benign breast tissues.
Neoplasms
Quantitative RT-PCR analysis and immunohistochemical localization of the kallikrein-related peptidases 13 and 14 in lung.
Neoplasms
Steroid hormone regulation and prognostic value of the human kallikrein gene 14 in ovarian cancer.
Neoplasms
The kallikrein 14 gene is down-regulated by androgen receptor signalling and harbours genetic variation that is associated with prostate tumour aggressiveness.
Neoplasms
The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.
Netherton Syndrome
Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin.
Netherton Syndrome
Toward the first class of suicide inhibitors of kallikreins involved in skin diseases.
Ovarian Neoplasms
Advanced high-grade serous ovarian cancer: inverse association of KLK13 and KLK14 mRNA levels in tumor tissue and patients' prognosis.
Ovarian Neoplasms
Cloning of a new member of the human kallikrein gene family, KLK14, which is down-regulated in different malignancies.
Ovarian Neoplasms
Effects of kallikrein-related peptidase 14 gene inhibition by small interfering RNA in ovarian carcinoma cells.
Ovarian Neoplasms
Human kallikrein 14: a new potential biomarker for ovarian and breast cancer.
Ovarian Neoplasms
Quantitative analysis of human kallikrein gene 14 expression in breast tumours indicates association with poor prognosis.
Ovarian Neoplasms
Steroid hormone regulation and prognostic value of the human kallikrein gene 14 in ovarian cancer.
Prostatic Neoplasms
Differential expression of the human kallikrein gene 14 (KLK14) in normal and cancerous prostatic tissues.
Prostatic Neoplasms
Expression and functional characterization of the cancer-related serine protease, human tissue kallikrein 14.
Prostatic Neoplasms
High expression of KLK14 in prostatic adenocarcinoma is associated with elevated risk of prostate-specific antigen relapse.
Prostatic Neoplasms
In vitro evidence that KLK14 regulates the components of the HGF/Met axis, pro-HGF and HGF-activator inhibitor 1A and 1B.
Prostatic Neoplasms
Kallikreins are involved in an miRNA network that contributes to prostate cancer progression.
Prostatic Neoplasms
KLK14 interactions with HAI-1 and HAI-2 serine protease inhibitors: A molecular dynamics and relative free-energy calculations study.
Prostatic Neoplasms
MSR1 repeats modulate gene expression and affect risk of breast and prostate cancer.
Prostatic Neoplasms
The kallikrein 14 gene is down-regulated by androgen receptor signalling and harbours genetic variation that is associated with prostate tumour aggressiveness.
Prostatic Neoplasms
The molecular function of kallikrein-related peptidase 14 demonstrates a key modulatory role in advanced prostate cancer.
Psoriasis
Aberrant human tissue kallikrein levels in the stratum corneum and serum of patients with psoriasis: dependence on phenotype, severity and therapy.
Skin Diseases
Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin.
Skin Diseases
Toward the first class of suicide inhibitors of kallikreins involved in skin diseases.
Skin Diseases
Transgenic kallikrein 14 mice display major hair shaft defects associated with desmoglein 3 and 4 degradation, abnormal epidermal differentiation and Il-36 signature.
Testicular Neoplasms
Quantitative analysis of human kallikrein gene 14 expression in breast tumours indicates association with poor prognosis.
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